MCID: ERY004
MIFTS: 43

Erysipelas malady

Infectious diseases category

Summaries for Erysipelas

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63Wikipedia, 32MalaCards
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Wikipedia:63 Erysipelas (/ɛrɨˈsɪpələs/; Greek ἐρυσίπελας—red skin; also known as \"Ignis sacer\",... more...

MalaCards: Erysipelas is related to familial mediterranean fever and necrotizing fasciitis. An important gene associated with Erysipelas is PI3 (peptidase inhibitor 3, skin-derived). The compounds hydroxychloroquine and blys have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and breast, and related mouse phenotype mortality/aging.

Aliases & Classifications for Erysipelas

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8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 60UMLS, 27ICD9CM, 34MeSH, 56SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

erysipelas 8 42 10 44 60


External Ids:

Disease Ontology8 DOID:11330
ICD9CM27 035
MeSH34 D004886
ICD1025 A46

Related Diseases for Erysipelas

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17GeneCards, 18GeneDecks
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Diseases related to Erysipelas via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 104)
idRelated DiseaseScoreTop Affiliating Genes
1familial mediterranean fever30.3TNF, MEFV
2necrotizing fasciitis30.2SPEG
3vasculitis30.1CD40LG, MEFV, TNF
4dermatitis30.0PIK3C2A
5myotonic dystrophy29.8PIK3C2A
6crohn's disease29.8TNF
7pharyngitis29.8SPEG
8ischemia29.8PIK3C2A, BDKRB1, AZU1
9pneumonia29.8PIK3C2A, PI3, TNF
10skin disease29.7TNF, PI3, ELN
11cellulitis10.6
12arthritis10.5
13lymphedema10.3
14erysipeloid10.3
15breast cancer10.2
16fasciitis10.2
17scarlet fever10.2
18lupus erythematosus10.1
19cholera10.0
20lymphangitis10.0
21mycosis fungoides10.0
22tinea pedis10.0
23elephantiasis10.0
24influenza10.0
25sarcoma10.0
26myocardial infarction10.0PIK3C2A
27diphtheria10.0AZU1
28hyperuricemia10.0PIK3C2A
29disseminated intravascular coagulation10.0PIK3C2A
30pyoderma gangrenosum10.0MEFV
31pericarditis10.0MEFV
32brucellosis10.0MEFV
33palindromic rheumatism10.0MEFV
34primary hyperoxaluria10.0TNF
35polyarteritis nodosa10.0MEFV
36galactosemia10.0TNF
37amyloidosis10.0MEFV
38acute myocardial infarction10.0MEFV, PIK3C2A
39autoimmune hemolytic anemia10.0CD40LG
40schnitzler syndrome10.0CD40LG
41endometriosis10.0ELN
42antiphospholipid syndrome10.0CD40LG
43schistosomiasis10.0CD40LG
44tumor necrosis factor receptor-associated periodic syndrome10.0TNF, MEFV
45multiple sclerosis10.0TNF
46toxic shock syndrome10.0SPEG, TNF
47tetanus10.0CD40LG
48blau syndrome10.0MEFV, TNF
49periodontal disease10.0TNF
50leptospirosis10.0PIK3C2A, CD40LG

Graphical network of the top 20 diseases related to Erysipelas:



Diseases related to erysipelas

Clinical Features for Erysipelas

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Drugs & Therapeutics for Erysipelas

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Erysipelas

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Anatomical Context for Erysipelas

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32MalaCards
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MalaCards organs/tissues related to Erysipelas:

32
Skin, Testes, Breast, Colon, Eye, B cells, Monocytes, Thyroid, Heart, Retina, Spleen, Lymph node, Bone, Pituitary

Animal Models for Erysipelas or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Erysipelas:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107687.3ELN, SPEG, CD40LG, MEFV, PIK3C2A, PHGDH

Publications for Erysipelas

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50PubMed
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Articles related to Erysipelas:

(show top 50)    (show all 491)
idTitleAuthorsYear
1
Genetic susceptibility to non-necrotizing erysipelas/cellulitis. (23437094)
2013
2
Erysipelas in a numbat (Myrmecobius fasciatus). (23505731)
2013
3
Capsular polysaccharide of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, and its modification with phosphorylcholine. (22949554)
2012
4
Outbreak of swine erysipelas in a semi-intensive wild boar farm in Spain. (21649879)
2011
5
Erysipelas caused by group A streptococcus activates the contact system and induces the release of heparin-binding protein. (20107486)
2010
6
Elements of renal injury in patients with erysipelas. (21428183)
2010
7
Elephantiasis, elastin, and chronic wound healing: 19th century and contemporary viewpoints relevant to hypotheses concerning lymphedema, leprosy, erysipelas, and psoriasis--review and reflections. (19499764)
2009
8
Risk factors for erysipelas of the leg in Tunisia: a multicenter case-control study. (16484815)
2006
9
Burden of illness of bacterial cellulitis and erysipelas of the leg in the Netherlands. (16898907)
2006
10
Involvement of Staphylococcus aureus in Erysipelas. (16319465)
2006
11
Helicobacter cinaedi-associated bacteraemia and erysipelas in an immunocompetent host: a diagnostic challenge. (16051580)
2005
12
Complicated mycosis fungoides mimicking facial erysipelas. (15949025)
2005
13
Cellulitis and erysipelas. (15652104)
2004
14
Cellulitis and erysipelas. (12230764)
2002
15
Collaborative study for the establishment of erysipelas ELISA coating antigen. European Biological Reference Preparation batch no. 1. (11705102)
2001
16
Wound erysipelas following appendectomy caused by group B beta-hemolytic Streptococcus (Streptococcus agalactiae). (12594879)
2001
17
Erysipelas melanomatosum. (10461656)
1999
18
Serovar, pathogenicity and antimicrobial susceptibility of erysipelothrix rhusiopathiae isolates from farmed wild boars (Sus scrofa) affected with septicemic erysipelas in Japan. (10607512)
1999
19
Sodium selenite as prophylaxis against erysipelas in secondary lymphedema. (9703790)
1998
20
Erysipelas-like mercury exanthem. (9197976)
1997
21
St. Anthony's fire: an eponym for ergotism, not erysipelas. (7604780)
1995
22
Erysipelas in quail and suspected erysipeloid in processing plant employees. (7794182)
1995
23
Secondary milia following bullous erysipelas. (7867383)
1994
24
Erysipelas in caged laying chickens and suspected erysipeloid in animal caretakers. (8507697)
1993
25
Skin concentrations of phenoxymethylpenicillin in patients with erysipelas. (1563809)
1992
26
Monoclonal antibodies preventing the development of polyarthritis in rats induced by experimental infection with erysipelas bacteria. (1570491)
1992
27
Ocular erysipelas. (1520122)
1992
28
Study of granulocyte function of peripheral blood in recurrent erysipelas. (2612708)
1989
29
Use of a live oral vaccine to immunize turkeys against erysipelas. (3202763)
1988
30
Necrotic bullous erysipelas. (3279727)
1988
31
Possible genetic variation in resistance of turkeys to erysipelas and fowl cholera. (6487197)
1984
32
In defense of erysipelas vaccine. (7364625)
1980
33
Erysipelas: facial lymphangitis. (265381)
1977
34
Erysipelas serum titration with sheep red blood cells passively sensitized with a cellular extract. (4743874)
1973
35
Plasma glucose, hydrocortisone, and insulin levels in acute swine erysipelas. (5121720)
1971
36
Erysipelas in the guinea-fowl. (5102155)
1971
37
Studies of Swine Erysipelas. V. Presence Of Erysipelothrix Rhusiopathiae in Apparently Healthy Pigs. (17648675)
1953
38
Recurrent, fixed erysipelas-like dermatophytid; ineffectiveness of antibiotics reported in a case. (13091418)
1953
39
Studies of Swine Erysipelas. III. Antigenic Characteristics of Strains of Erysipelothrix Rhusiopathiae Isolated in Different Areas in Canada. (17648567)
1952
40
Studies of Swine Erysipelas. I. Literature Review and Survey of Erysipelothrix Rhusiopathiae Infection in Canada. (17648552)
1952
41
Outbreak of acute swine erysipelas in a Southland piggery. (14838808)
1951
42
Swine erysipelas in turkeys infects man with erysipeloid. (18119845)
1949
43
Food handler's infection (swine erysipelas) in man. (18131686)
1949
44
Discussion on swine erysipelas infection, Erysipelothrix rhusiopathiae, in man and animals. (18864715)
1948
45
Erysipelas in Infants. (21433819)
1939
46
Erysipelas Successfully cured by Subcutaneous Injection of Cows' Milk. (20315207)
1924
47
A NOTE ON THE TREATMENT OF CUTANEOUS ERYSIPELAS WITH BRILLIANT GREEN. (20770071)
1920
48
The Treatment of Inoperable Sarcoma by Bacterial Toxins (the Mixed Toxins of the Streptococcus erysipelas and the Bacillus prodigiosus). (19974799)
1910
49
Vitiligo as a Sequela of Influenza and Erysipelas. (20753304)
1891
50
On the Use of the Nitrate of Silver in the Cure of Erysipelas. (20794266)
1847

Genetic Variations for Erysipelas

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Expression for genes affiliated with Erysipelas

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Erysipelas

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Pathways for genes affiliated with Erysipelas

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Compounds for genes affiliated with Erysipelas

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44Novoseek, 11DrugBank, 49PharmGKB, 28IUPHAR, 24HMDB, 59Tocris Bioscience, 2BitterDB
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Compounds related to Erysipelas according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1hydroxychloroquine44 1111.0CD40LG, TNF
2blys4410.0CD40LG, TNF
3silicone449.8ELN, CD40LG
4okt3449.8ELN, CD40LG, TNF
5fenofibrate44 49 1111.7CD40LG, PIK3C2A, TNF
6atorvastatin44 49 28 11 2413.6TNF, PIK3C2A, CD40LG
7histamine44 28 2411.5TNF, PI3, CD40LG, ELN
8superoxide44 2410.5PI3, TNF, AZU1
9il-12449.5CD40LG, TNF
10ivig449.4ELN, CD40LG, PIK3C2A, TNF
11fibrinogen449.4TNF, PIK3C2A, CD40LG, ELN
12hyaluronic acid44 2410.3AZU1, CD40LG, ELN
13cyclosporin a44 28 5911.3TNF, PI3, PIK3C2A, CD40LG
14endotoxin449.3AZU1, TNF, MEFV, CD40LG
15lactate449.2TNF, PIK3C2A, CD40LG, ELN
16actinomycin d449.1BDKRB1, TNF, CD40LG, ELN
17genistein44 28 59 2 11 2414.1ELN, CD40LG, TNF, BDKRB1
18vegf448.8ELN, CD40LG, PIK3C2A, TNF, AZU1
19heparin44 28 11 2411.8ELN, CD40LG, PIK3C2A, AZU1
20retinoic acid44 249.7ELN, CD40LG, PI3, TNF, AZU1
21serine448.5AZU1, TNF, PHGDH, PI3, CD40LG, ELN

GO Terms for genes affiliated with Erysipelas

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16Gene Ontology
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Biological processes related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of immunoglobulin secretionGO:0510239.8CD40LG, TNF
2inflammatory responseGO:0069548.0CD40LG, MEFV, TNF, BDKRB1, AZU1

Molecular functions related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.8CD40LG, TNF

Products for genes affiliated with Erysipelas

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Erysipelas

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet