MCID: ERY004
MIFTS: 50

Erysipelas malady

Rare diseases, Infectious diseases, Skin diseases categories
Download this MalaCard

Summaries for Erysipelas

About this section


Fully expand this MalaCard
Wikipedia:65 Erysipelas (/?r??s?p?l?s/; Greek ???????????red skin; also known as \"Ignis sacer\", \"holy fire\", and... more...

MalaCards based summary: Erysipelas is related to familial mediterranean fever and pneumonia. An important gene associated with Erysipelas is PI3 (peptidase inhibitor 3, skin-derived), and among its related pathways are Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways and NF-kappa B signaling pathway. The compounds silicone and glutaraldehyde have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and breast, and related mouse phenotypes are integument and skeleton.

Aliases & Classifications for Erysipelas

About this section

Erysipelas, Aliases & Descriptions:

Name: Erysipelas 8 42 10 44 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases
Anatomical: Skin diseases


External Ids:

Disease Ontology8 DOID:11330
ICD9CM27 035
MeSH34 D004886
ICD1025 A46

Related Diseases for Erysipelas

About this section

Diseases related to Erysipelas via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 96)
idRelated DiseaseScoreTop Affiliating Genes
1familial mediterranean fever30.7TNF, MEFV
2pneumonia30.0PI3, TNF, PIK3C2A
3vasculitis30.0MEFV, TNF, CD40LG
4ischemia29.8PIK3C2A, BDKRB1, AZU1
5skin disease29.8ELN, TNF, PI3
6hepatitis c29.5CD40LG, TNF
7cellulitis10.7
8arthritis10.5
9calcinosis10.4PIK3C2A
10palindromic rheumatism10.4MEFV
11lymphedema10.4
12polyarteritis nodosa10.4MEFV
13erysipeloid10.3
14schnitzler syndrome10.3CD40LG
15breast cancer10.3
16fasciitis10.3
17hemorrhagic fever10.3CD40LG
18scrub typhus10.3CD40LG
19necrotizing fasciitis10.2
20scarlet fever10.2
21adult respiratory distress syndrome10.2PI3, TNF
22periodic fever, familial, autosomal dominant10.2MEFV, TNF
23blau syndrome10.2MEFV, TNF
24respiratory failure10.2TNF, PIK3C2A
25lupus erythematosus10.2
26discoid lupus erythematosus10.2
27behcet's disease10.1TNF, MEFV
28leptospirosis10.1CD40LG, PIK3C2A
29mycosis fungoides10.1
30cholera10.1
31lymphangitis10.1
32tinea pedis10.1
33dermatitis10.1
34elephantiasis10.1
35influenza10.1
36myocarditis10.1
37sarcoma10.1
38st anthony's fire10.1
39bacteremia10.1
40dengue disease10.1CD40LG, PIK3C2A
41septic shock10.0PIK3C2A, TNF
42sepsis10.0PI3, AZU1, TNF
43peritonitis10.0TNF, AZU1, MEFV
44chronic obstructive pulmonary disease10.0ELN, TNF, PI3
45ankylosing spondylitis10.0TNF, CD40LG
46cork-handlers' disease10.0ELN, PI3, TNF
47vascular disease10.0ELN, PIK3C2A, TNF
48thrombocytopenia9.9AZU1, CD40LG, PIK3C2A
49b-cell lymphomas9.9
50crohn's disease9.9

Graphical network of the top 20 diseases related to Erysipelas:



Diseases related to erysipelas

Symptoms for Erysipelas

About this section

Drugs & Therapeutics for Erysipelas

About this section

Drug clinical trials:

Search ClinicalTrials for Erysipelas

Search NIH Clinical Center for Erysipelas

Genetic Tests for Erysipelas

About this section

Anatomical Context for Erysipelas

About this section

MalaCards organs/tissues related to Erysipelas:

32
Skin, Testes, Breast, Colon, Eye, Bone, Lymph node, Spleen, Retina, Heart, Thyroid, Monocytes, B cells, Pituitary, Neutrophil

Animal Models for Erysipelas or affiliated genes

About this section

MGI Mouse Phenotypes related to Erysipelas:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.6BDKRB1, CD40LG, MEFV, TNF
2MP:00053908.4TNF, ELN, MEFV, CD40LG
3MP:00053877.9PIK3C2A, TNF, MEFV, CD40LG, BDKRB1
4MP:00053767.6BDKRB1, CD40LG, MEFV, ELN, TNF, PIK3C2A
5MP:00107687.6PIK3C2A, TNF, ELN, MEFV, CD40LG, BDKRB1

Publications for Erysipelas

About this section

Articles related to Erysipelas:

(show top 50)    (show all 495)
idTitleAuthorsYear
1
Erysipelothrix rhusiopathiae contamination in the poultry house environment during erysipelas outbreaks in organic laying hen flocks. (24661145)
2014
2
Erysipelas-like Erythema in a Patient with Familial Mediterranean Fever. (25362709)
2014
3
Prevalence of Met-203 type spaA variant in Erysipelothrix rhusiopathiae isolates and the efficacy of swine erysipelas vaccines in Japan. (24405986)
2014
4
Risk of deep vein thrombosis in patients with cellulitis and erysipelas: a systematic review and meta-analysis. (23948644)
2013
5
Capsular polysaccharide of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, and its modification with phosphorylcholine. (22949554)
2012
6
The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of firmicutes and the organism's intracellular adaptations. (21478354)
2011
7
Characterization of Erysipelothrix species isolates from clinically affected pigs, environmental samples, and vaccine strains from six recent swine erysipelas outbreaks in the United States. (20719987)
2010
8
Erysipelas: a common potentially dangerous infection. (17994173)
2007
9
Risk factors for erysipelas of the leg in Tunisia: a multicenter case-control study. (16484815)
2006
10
A blistering disease: bullous erysipelas. (16880441)
2006
11
Oedema as a risk factor for multiple episodes of cellulitis/erysipelas of the lower leg: a series with community follow-up. (17034523)
2006
12
Bullous erysipelas: clinical presentation, staphylococcal involvement and methicillin resistance. (16319471)
2006
13
Erysipelas after breast cancer treatment (26 cases). (16409908)
2005
14
Wound healing of chronic leg ulcers under the influence of erysipelas. (14965798)
2004
15
Cellulitis and erysipelas. (15865787)
2004
16
Oral pristinamycin versus standard penicillin regimen to treat erysipelas in adults: randomised, non-inferiority, open trial. (12386036)
2002
17
Lymphoscintigraphic evaluation in patients after erysipelas. (11191659)
2000
18
Erysipelas and tinea pedis. (10948816)
2000
19
Erysipelas in malleefowl. (10451726)
1999
20
Erysipelas: clinical and bacteriologic spectrum and serological aspects. (8922808)
1996
21
St. Anthony's fire: an eponym for ergotism, not erysipelas. (7604780)
1995
22
Pre-septal cellulitis and facial erysipelas due to Moraxella species. (7955474)
1994
23
Streptococcal arthritis and erysipelas complicating dental extraction. (8422570)
1993
24
Facial erysipelas: report of a case and review of the literature. (1890524)
1991
25
Erysipelas. (2228369)
1990
26
Erysipelas complicating chronic discoid lupus erythematosus of the face--a case report and review of erysipelas. (2680180)
1989
27
Study of granulocyte function of peripheral blood in recurrent erysipelas. (2612708)
1989
28
Lucigenin-amplified chemiluminescence in blood and synovial fluid phagocytes of pigs with erysipelas arthritis. (4096165)
1985
29
Prophylactic antibiotics in recurrent erysipelas. (2857399)
1985
30
Serotypes of Erysipelothrix rhusiopathiae strains isolated from slaughter pigs affected with chronic erysipelas. (6748441)
1984
31
Septic prepatellar bursitis due to erysipelas. (7306248)
1981
32
In defense of erysipelas vaccine. (7364625)
1980
33
Granulomatous lesions in pigs associated with the use of an oil-based erysipelas vaccine. (614024)
1977
34
The histochemistry of prefascial lymph vessels in recurrent erysipelas. (4148228)
1973
35
Leukocyte migration test in recurrent erysipelas. (4120805)
1973
36
Triple sugar iron agar as an aid in the diagnosis of erysipelas. (13598680)
1958
37
Modified Swine Erysipelas Vaccine. (17649050)
1958
38
The incidence of arthritis in swine following vaccination for swine erysipelas. (13498229)
1958
39
Experimental evaluation of culture and serum vaccination for the control of swine erysipelas. V. Vaccination of weanling pigs using a change in the dosage relationship of culture and serum. (13201496)
1954
40
Studies of Swine Erysipelas. II. Cultural Characteristics and Virulence of Strains of Erysipelothrix Rhusiopathiae Isolated in Canada. (17648553)
1952
41
Erysipelas in turkeys; a case report. (18124860)
1949
42
DIFFERENTIAL diagnosis of swine erysipelas. (20988172)
1946
43
SPECIES SPECIFIC IMMUNITY TO HEMOLYTIC STREPTOCOCCUS INFECTIONS INDUCED IN WHITE MICE BY IMMUNIZATION WITH AN R VARIANT OF AN ERYSIPELAS STRAIN : The Significance of Cell Autolysis in Relation to Antibody Response. (16560103)
1938
44
Erysipelas. (18744161)
1937
45
The Statistics of Erysipelas in England and Wales. (20475199)
1933
46
Relationship of the Streptococci Causing Erysipelas. (18012891)
1929
47
Syphilitic Meningo-Myelitis: Erysipelas: Recovery. (20759725)
1901
48
Seasonable Influences in Erysipelas, with Statistics. (21409070)
1895
49
A Case of Erysipelas Neonatorum Treated by Antistreptococcic Serum. (20755865)
1895
50
Vitiligo as a Sequela of Influenza and Erysipelas. (20753304)
1891

Variations for Erysipelas

About this section

Expression for genes affiliated with Erysipelas

About this section
Expression patterns in normal tissues for genes affiliated with Erysipelas

Search GEO for disease gene expression data for Erysipelas.

Pathways for genes affiliated with Erysipelas

About this section

Pathways related to Erysipelas according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6MEFV, TNF
29.5CD40LG, TNF
3
Show member pathways
Calcium signaling in the CD4+ TCR pathway37
9.5CD40LG, TNF
4
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway60
9.5CD40LG, TNF
59.5CD40LG, TNF
6
Show member pathways
9.3PIK3C2A, TNF

Compounds for genes affiliated with Erysipelas

About this section

Compounds related to Erysipelas according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1silicone4410.0ELN, CD40LG
2glutaraldehyde449.9ELN, CD40LG
3hydroxychloroquine44 1110.9TNF, CD40LG
4blys449.9TNF, CD40LG
5il-12449.9CD40LG, TNF
6lactose44 1110.8CD40LG, ELN
7sulfasalazine28 44 50 1112.8CD40LG, TNF
8doxycycline44 1110.8ELN, CD40LG
9mycophenolate mofetil44 50 1111.8CD40LG, TNF
10hirudin449.7PIK3C2A, CD40LG
11erythromycin44 2 50 1112.6CD40LG, PIK3C2A
12neopterin449.6TNF, CD40LG
13okt3449.5TNF, ELN, CD40LG
14theophylline44 28 24 1112.5CD40LG, ELN
15melphalan44 50 1111.5TNF, PIK3C2A
16rituximab44 50 1111.5CD40LG, TNF
17dermatan sulfate449.5ELN, AZU1
18n acetylcysteine449.5CD40LG, ELN, TNF
19indomethacin44 28 61 1112.4CD40LG, ELN, TNF
20sb 20358044 6110.4BDKRB1, TNF, PI3
21ascorbic acid44 2410.3PIK3C2A, ELN, CD40LG
22thromboxane a244 2410.3BDKRB1, PIK3C2A
23fenofibrate44 50 1111.3CD40LG, TNF, PIK3C2A
24atorvastatin44 50 28 24 1113.3PIK3C2A, TNF, CD40LG
25ly294002449.3TNF, PIK3C2A, PI3
26hyaluronic acid44 2410.2CD40LG, ELN, AZU1
27histamine44 28 2411.2CD40LG, ELN, TNF, PI3
28dexamethasone44 50 28 1112.1CD40LG, ELN, TNF, PI3
29creatinine449.1PIK3C2A, ELN, CD40LG
30polysaccharide449.1CD40LG, ELN, AZU1
31aspartate449.1CD40LG, ELN, PIK3C2A
32actinomycin d449.0TNF, ELN, CD40LG, BDKRB1
33genistein44 28 61 2 24 1114.0TNF, ELN, CD40LG, BDKRB1
34cyclosporin a44 28 6111.0CD40LG, TNF, PIK3C2A, PI3
35ivig448.9CD40LG, ELN, TNF, PIK3C2A
36fibrinogen448.9PIK3C2A, TNF, ELN, CD40LG
37lactate448.9PIK3C2A, TNF, ELN, CD40LG
38endotoxin448.8CD40LG, MEFV, TNF, AZU1
39cycloheximide448.7TNF, ELN, BDKRB1
40superoxide44 249.6AZU1, PI3, PIK3C2A, TNF
41heparin44 28 24 1111.6CD40LG, ELN, PIK3C2A, AZU1
42arginine448.6CD40LG, ELN, PIK3C2A, AZU1
43glutamate448.5AZU1, PIK3C2A, ELN, CD40LG
44oxygen44 249.5AZU1, PI3, PIK3C2A, TNF
45lipid448.4AZU1, PI3, PIK3C2A, TNF
46retinoic acid44 249.4CD40LG, ELN, TNF, PI3, AZU1
47serine448.3AZU1, PI3, TNF, ELN, CD40LG
48tyrosine448.2AZU1, PI3, PIK3C2A, MEFV, BDKRB1
49vegf448.1AZU1, PIK3C2A, TNF, ELN, CD40LG
50calcium44 50 24 1111.1AZU1, PI3, PIK3C2A, ELN, BDKRB1

GO Terms for genes affiliated with Erysipelas

About this section

Biological processes related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1organ morphogenesisGO:0098879.5ELN, TNF
2regulation of immunoglobulin secretionGO:0510239.5CD40LG, TNF
3response to mechanical stimulusGO:0096129.1BDKRB1, TNF
4protein kinase C-activating G-protein coupled receptor signaling pathwayGO:0072059.0BDKRB1, AZU1
5inflammatory responseGO:0069547.8BDKRB1, CD40LG, MEFV, TNF, AZU1

Molecular functions related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.5CD40LG, TNF

Products for genes affiliated with Erysipelas

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Erysipelas

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet