MCID: ERY004
MIFTS: 50

Erysipelas malady

Rare diseases, Infectious diseases, Skin diseases categories

Summaries for Erysipelas

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66Wikipedia, 34MalaCards
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Wikipedia:66 Erysipelas (/?r??s?p?l?s/; Greek ???????????red skin; also known as \"Ignis sacer\", \"holy fire\", and... more...

MalaCards: Erysipelas is related to familial mediterranean fever and vasculitis. An important gene associated with Erysipelas is PI3 (peptidase inhibitor 3, skin-derived), and among its related pathways are Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways and NF-kappa B signaling pathway. The compounds silicone and glutaraldehyde have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and breast, and related mouse phenotypes are integument and skeleton.

Aliases & Classifications for Erysipelas

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9Disease Ontology, 44NIH Rare Diseases, 11DISEASES, 46Novoseek, 63UMLS, 36MeSH, 28ICD9CM, 59SNOMED-CT, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases
Anatomical: Skin diseases


Aliases & Descriptions:

erysipelas 9 44 11 46 63


External Ids:

Disease Ontology9 DOID:11330
MeSH36 D004886
ICD9CM28 035
ICD1026 A46

Related Diseases for Erysipelas

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18GeneCards, 19GeneDecks
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Diseases related to Erysipelas via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 94)
idRelated DiseaseScoreTop Affiliating Genes
1familial mediterranean fever30.4TNF, MEFV
2vasculitis30.2MEFV, TNF, CD40LG
3pneumonia29.9PI3, TNF, PIK3C2A
4ischemia29.8PIK3C2A, BDKRB1, AZU1
5skin disease29.8ELN, TNF, PI3
6hepatitis c29.8CD40LG, TNF
7cellulitis10.6
8arthritis10.5
9lymphedema10.4
10erysipeloid10.3
11breast cancer10.3
12fasciitis10.3
13necrotizing fasciitis10.2
14scarlet fever10.1
15lupus erythematosus10.1
16discoid lupus erythematosus10.1
17calcinosis10.1PIK3C2A
18palindromic rheumatism10.1MEFV
19polyarteritis nodosa10.1MEFV
20schnitzler syndrome10.1CD40LG
21hemorrhagic fever10.1CD40LG
22scrub typhus10.1CD40LG
23cholera10.1
24lymphangitis10.1
25mycosis fungoides10.1
26tinea pedis10.1
27dermatitis10.1
28elephantiasis10.1
29influenza10.1
30sarcoma10.1
31st anthony's fire10.1
32bacteremia10.1
33adult respiratory distress syndrome10.0PI3, TNF
34periodic fever, familial, autosomal dominant10.0MEFV, TNF
35blau syndrome10.0MEFV, TNF
36respiratory failure10.0TNF, PIK3C2A
37behcet's disease10.0TNF, MEFV
38leptospirosis10.0CD40LG, PIK3C2A
39dengue disease10.0CD40LG, PIK3C2A
40septic shock10.0PIK3C2A, TNF
41sepsis10.0PI3, AZU1, TNF
42peritonitis10.0TNF, AZU1, MEFV
43pulmonary disease, chronic obstructive10.0ELN, TNF, PI3
44ankylosing spondylitis10.0TNF, CD40LG
45cork-handlers' disease10.0ELN, PI3, TNF
46vascular disease10.0ELN, PIK3C2A, TNF
47thrombocytopenia10.0AZU1, CD40LG, PIK3C2A
48connective tissue disease10.0TNF, CD40LG
49iga glomerulonephritis10.0MEFV, CD40LG
50rheumatic disease10.0MEFV, CD40LG, TNF

Graphical network of the top 20 diseases related to Erysipelas:



Diseases related to erysipelas

Symptoms for Erysipelas

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Drugs & Therapeutics for Erysipelas

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Erysipelas

Drug clinical trials:

Search ClinicalTrials for Erysipelas

Search NIH Clinical Center for Erysipelas

Search CenterWatch for Erysipelas

Genetic Tests for Erysipelas

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Anatomical Context for Erysipelas

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34MalaCards
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MalaCards organs/tissues related to Erysipelas:

34
Skin, Testes, Breast, Colon, Eye, B cells, Monocytes, Thyroid, Heart, Retina, Spleen, Lymph node, Bone, Pituitary

Animal Models for Erysipelas or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Erysipelas:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.6BDKRB1, CD40LG, MEFV, TNF
2MP:00053908.4TNF, ELN, MEFV, CD40LG
3MP:00053877.9PIK3C2A, TNF, MEFV, CD40LG, BDKRB1
4MP:00053767.6BDKRB1, CD40LG, MEFV, ELN, TNF, PIK3C2A
5MP:00107687.6PIK3C2A, TNF, ELN, MEFV, CD40LG, BDKRB1

Publications for Erysipelas

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53PubMed
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Articles related to Erysipelas:

(show top 50)    (show all 487)
idTitleAuthorsYear
1
Prevalence of Met-203 type spaA variant in Erysipelothrix rhusiopathiae isolates and the efficacy of swine erysipelas vaccines in Japan. (24405986)
2014
2
Risk of deep vein thrombosis in patients with cellulitis and erysipelas: a systematic review and meta-analysis. (23948644)
2013
3
Capsular polysaccharide of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, and its modification with phosphorylcholine. (22949554)
2012
4
The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of firmicutes and the organism's intracellular adaptations. (21478354)
2011
5
Characterization of Erysipelothrix species isolates from clinically affected pigs, environmental samples, and vaccine strains from six recent swine erysipelas outbreaks in the United States. (20719987)
2010
6
Erysipelas: a common potentially dangerous infection. (17994173)
2007
7
Risk factors for erysipelas of the leg in Tunisia: a multicenter case-control study. (16484815)
2006
8
A blistering disease: bullous erysipelas. (16880441)
2006
9
Oedema as a risk factor for multiple episodes of cellulitis/erysipelas of the lower leg: a series with community follow-up. (17034523)
2006
10
Bullous erysipelas: clinical presentation, staphylococcal involvement and methicillin resistance. (16319471)
2006
11
Erysipelas after breast cancer treatment (26 cases). (16409908)
2005
12
Wound healing of chronic leg ulcers under the influence of erysipelas. (14965798)
2004
13
Cellulitis and erysipelas. (15865787)
2004
14
Oral pristinamycin versus standard penicillin regimen to treat erysipelas in adults: randomised, non-inferiority, open trial. (12386036)
2002
15
Lymphoscintigraphic evaluation in patients after erysipelas. (11191659)
2000
16
Erysipelas and tinea pedis. (10948816)
2000
17
Erysipelas in malleefowl. (10451726)
1999
18
Erysipelas: clinical and bacteriologic spectrum and serological aspects. (8922808)
1996
19
St. Anthony's fire: an eponym for ergotism, not erysipelas. (7604780)
1995
20
Erysipelas in quail and suspected erysipeloid in processing plant employees. (7794182)
1995
21
Pre-septal cellulitis and facial erysipelas due to Moraxella species. (7955474)
1994
22
Streptococcal arthritis and erysipelas complicating dental extraction. (8422570)
1993
23
Facial erysipelas: report of a case and review of the literature. (1890524)
1991
24
Erysipelas. (2228369)
1990
25
Erysipelas complicating chronic discoid lupus erythematosus of the face--a case report and review of erysipelas. (2680180)
1989
26
Study of granulocyte function of peripheral blood in recurrent erysipelas. (2612708)
1989
27
Lucigenin-amplified chemiluminescence in blood and synovial fluid phagocytes of pigs with erysipelas arthritis. (4096165)
1985
28
Prophylactic antibiotics in recurrent erysipelas. (2857399)
1985
29
Serotypes of Erysipelothrix rhusiopathiae strains isolated from slaughter pigs affected with chronic erysipelas. (6748441)
1984
30
Septic prepatellar bursitis due to erysipelas. (7306248)
1981
31
In defense of erysipelas vaccine. (7364625)
1980
32
Granulomatous lesions in pigs associated with the use of an oil-based erysipelas vaccine. (614024)
1977
33
The histochemistry of prefascial lymph vessels in recurrent erysipelas. (4148228)
1973
34
Leukocyte migration test in recurrent erysipelas. (4120805)
1973
35
Triple sugar iron agar as an aid in the diagnosis of erysipelas. (13598680)
1958
36
Modified Swine Erysipelas Vaccine. (17649050)
1958
37
The incidence of arthritis in swine following vaccination for swine erysipelas. (13498229)
1958
38
Laboratory studies on erysipelas. II. Use of various cultures in production of infection in pigs by skin scarification. (13283239)
1956
39
Experimental evaluation of culture and serum vaccination for the control of swine erysipelas. V. Vaccination of weanling pigs using a change in the dosage relationship of culture and serum. (13201496)
1954
40
Studies of Swine Erysipelas. II. Cultural Characteristics and Virulence of Strains of Erysipelothrix Rhusiopathiae Isolated in Canada. (17648553)
1952
41
Erysipelas in turkeys; a case report. (18124860)
1949
42
DIFFERENTIAL diagnosis of swine erysipelas. (20988172)
1946
43
SPECIES SPECIFIC IMMUNITY TO HEMOLYTIC STREPTOCOCCUS INFECTIONS INDUCED IN WHITE MICE BY IMMUNIZATION WITH AN R VARIANT OF AN ERYSIPELAS STRAIN : The Significance of Cell Autolysis in Relation to Antibody Response. (16560103)
1938
44
Erysipelas. (18744161)
1937
45
The Statistics of Erysipelas in England and Wales. (20475199)
1933
46
Relationship of the Streptococci Causing Erysipelas. (18012891)
1929
47
Syphilitic Meningo-Myelitis: Erysipelas: Recovery. (20759725)
1901
48
Seasonable Influences in Erysipelas, with Statistics. (21409070)
1895
49
A Case of Erysipelas Neonatorum Treated by Antistreptococcic Serum. (20755865)
1895
50
Vitiligo as a Sequela of Influenza and Erysipelas. (20753304)
1891

Variations for Erysipelas

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Expression for genes affiliated with Erysipelas

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Erysipelas

Search GEO for disease gene expression data for Erysipelas.

Pathways for genes affiliated with Erysipelas

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51PathCards, 56Reactome, 39NCBI BioSystems Database, 31KEGG, 61Thomson Reuters, 52PharmGKB
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Pathways related to Erysipelas according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6MEFV, TNF
29.5CD40LG, TNF
3
Show member pathways
Calcium signaling in the CD4+ TCR pathway39
9.5CD40LG, TNF
4
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway61
9.5CD40LG, TNF
59.5CD40LG, TNF
6
Show member pathways
9.3PIK3C2A, TNF

Compounds for genes affiliated with Erysipelas

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46Novoseek, 12DrugBank, 30IUPHAR, 52PharmGKB, 3BitterDB, 25HMDB, 62Tocris Bioscience
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Compounds related to Erysipelas according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1silicone4610.0ELN, CD40LG
2glutaraldehyde469.9ELN, CD40LG
3hydroxychloroquine46 1210.9TNF, CD40LG
4blys469.9TNF, CD40LG
5il-12469.9CD40LG, TNF
6lactose46 1210.8CD40LG, ELN
7sulfasalazine30 46 52 1212.8CD40LG, TNF
8doxycycline46 1210.8ELN, CD40LG
9mycophenolate mofetil46 52 1211.8CD40LG, TNF
10hirudin469.7PIK3C2A, CD40LG
11erythromycin46 3 52 1212.6CD40LG, PIK3C2A
12neopterin469.6TNF, CD40LG
13okt3469.5TNF, ELN, CD40LG
14theophylline46 30 25 1212.5CD40LG, ELN
15melphalan46 52 1211.5TNF, PIK3C2A
16rituximab46 52 1211.5CD40LG, TNF
17dermatan sulfate469.5ELN, AZU1
18n acetylcysteine469.5CD40LG, ELN, TNF
19indomethacin46 30 62 1212.4CD40LG, ELN, TNF
20sb 20358046 6210.4BDKRB1, TNF, PI3
21ascorbic acid46 2510.3PIK3C2A, ELN, CD40LG
22thromboxane a246 2510.3BDKRB1, PIK3C2A
23fenofibrate46 52 1211.3CD40LG, TNF, PIK3C2A
24atorvastatin46 52 30 25 1213.3PIK3C2A, TNF, CD40LG
25ly294002469.3TNF, PIK3C2A, PI3
26hyaluronic acid46 2510.2CD40LG, ELN, AZU1
27histamine46 30 2511.2CD40LG, ELN, TNF, PI3
28dexamethasone46 52 30 1212.1CD40LG, ELN, TNF, PI3
29creatinine469.1PIK3C2A, ELN, CD40LG
30polysaccharide469.1CD40LG, ELN, AZU1
31aspartate469.1CD40LG, ELN, PIK3C2A
32actinomycin d469.0TNF, ELN, CD40LG, BDKRB1
33genistein46 30 62 3 25 1214.0TNF, ELN, CD40LG, BDKRB1
34cyclosporin a46 30 6211.0CD40LG, TNF, PIK3C2A, PI3
35ivig468.9CD40LG, ELN, TNF, PIK3C2A
36fibrinogen468.9PIK3C2A, TNF, ELN, CD40LG
37lactate468.9PIK3C2A, TNF, ELN, CD40LG
38endotoxin468.8CD40LG, MEFV, TNF, AZU1
39cycloheximide468.7TNF, ELN, BDKRB1
40superoxide46 259.6AZU1, PI3, PIK3C2A, TNF
41heparin46 30 25 1211.6CD40LG, ELN, PIK3C2A, AZU1
42arginine468.6CD40LG, ELN, PIK3C2A, AZU1
43glutamate468.5AZU1, PIK3C2A, ELN, CD40LG
44oxygen46 259.5AZU1, PI3, PIK3C2A, TNF
45lipid468.4AZU1, PI3, PIK3C2A, TNF
46retinoic acid46 259.4CD40LG, ELN, TNF, PI3, AZU1
47serine468.3AZU1, PI3, TNF, ELN, CD40LG
48tyrosine468.2AZU1, PI3, PIK3C2A, MEFV, BDKRB1
49vegf468.1AZU1, PIK3C2A, TNF, ELN, CD40LG
50calcium46 52 25 1211.1AZU1, PI3, PIK3C2A, ELN, BDKRB1

GO Terms for genes affiliated with Erysipelas

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17Gene Ontology
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Biological processes related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1organ morphogenesisGO:0098879.5ELN, TNF
2regulation of immunoglobulin secretionGO:0510239.5TNF, CD40LG
3response to mechanical stimulusGO:0096129.1BDKRB1, TNF
4protein kinase C-activating G-protein coupled receptor signaling pathwayGO:0072059.0BDKRB1, AZU1
5inflammatory responseGO:0069547.8BDKRB1, CD40LG, MEFV, TNF, AZU1

Molecular functions related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.5CD40LG, TNF

Products for genes affiliated with Erysipelas

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Sources for Erysipelas

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet