MCID: ERY004
MIFTS: 41

Erysipelas malady

Infectious category

Summaries for Erysipelas

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Erysipelas (/ɛrɨˈsɪpələs/; Greek ἐρυσίπελας—red skin; also known as \"Ignis sacer\",... more...

MalaCards: Erysipelas is related to familial mediterranean fever and necrotizing fasciitis. An important gene associated with Erysipelas is PI3 (peptidase inhibitor 3, skin-derived). The compounds hydroxychloroquine and blys have been mentioned in the context of this disorder. Affiliated tissues include whole blood, lymph node and spleen, and related mouse phenotype mortality/aging.

Aliases & Classifications for Erysipelas

Sources:
8Disease Ontology, 43NIH Rare Diseases, 10DISEASES, 45Novoseek, 61UMLS, 27ICD9CM, 35MeSH, 57SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious


Aliases & Descriptions:

erysipelas 8 43 10 45 61


External Ids:

Disease Ontology8 DOID:11330
ICD9CM27 035
MeSH35 D004886
ICD1025 A46

Related Diseases for Erysipelas

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Erysipelas via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 82)
idRelated DiseaseScoreTop Affiliating Genes
1familial mediterranean fever30.4TNF, MEFV
2necrotizing fasciitis30.3SPEG
3vasculitis30.2CD40LG, MEFV, TNF
4pharyngitis29.8SPEG
5cellulitis10.7
6arthritis10.5
7erysipeloid10.3
8scarlet fever10.2
9discoid lupus erythematosus10.2
10cholera10.1
11lymphangitis10.1
12mycosis fungoides10.1
13tinea pedis10.1
14urticaria10.1
15bacteremia10.1
16myocardial infarction10.0PIK3C2A
17diphtheria10.0AZU1
18hyperuricemia10.0PIK3C2A
19disseminated intravascular coagulation10.0PIK3C2A
20pyoderma gangrenosum10.0MEFV
21pericarditis10.0MEFV
22brucellosis10.0MEFV
23palindromic rheumatism10.0MEFV
24myotonic dystrophy10.0PIK3C2A
25primary hyperoxaluria10.0TNF
26polyarteritis nodosa10.0MEFV
27crohn's disease10.0TNF
28galactosemia10.0TNF
29amyloidosis10.0MEFV
30acute myocardial infarction10.0MEFV, PIK3C2A
31autoimmune hemolytic anemia10.0CD40LG
32schnitzler syndrome10.0CD40LG
33endometriosis10.0ELN
34antiphospholipid syndrome10.0CD40LG
35schistosomiasis10.0CD40LG
36tumor necrosis factor receptor-associated periodic syndrome10.0TNF, MEFV
37multiple sclerosis10.0TNF
38toxic shock syndrome10.0SPEG, TNF
39tetanus10.0CD40LG
40dermatitis10.0PIK3C2A
41ischemia10.0PIK3C2A, BDKRB1, AZU1
42blau syndrome10.0MEFV, TNF
43periodontal disease10.0TNF
44pneumonia10.0PIK3C2A, PI3, TNF
45leptospirosis10.0PIK3C2A, CD40LG
46myeloma10.0CD40LG
47glomerulonephritis10.0CD40LG, AZU1
48adult respiratory distress syndrome10.0PI3, TNF
49peritonitis10.0MEFV, TNF, AZU1
50melanoma10.0AZU1, TNF, MEFV

Graphical network of the top 20 diseases related to Erysipelas:



Diseases related to erysipelas

Clinical Features for Erysipelas

Drugs & Therapeutics for Erysipelas

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Erysipelas

Search CenterWatch for Erysipelas

Genetic Tests for Erysipelas

Anatomical Context for Erysipelas

Sources:
33MalaCards
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MalaCards organs/tissues related to Erysipelas:

33
Whole blood, Lymph node, Spleen, Retina, Heart, Colon, Thyroid, Breast, Skin, Monocytes, T cells, B cells, Pituitary

Animal Models for Erysipelas or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Erysipelas:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107687.3ELN, SPEG, CD40LG, MEFV, PIK3C2A, PHGDH

Publications for Erysipelas

Sources:
51PubMed
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Articles related to Erysipelas:

(show top 50)    (show all 492)
idTitleAuthorsYear
1
Risk of deep vein thrombosis in patients with cellulitis and erysipelas: a systematic review and meta-analysis. (23948644)
2013
2
Leukocytoclastic vasculitis secondary to erysipelas: an unusual case of noncryoglobulinemic vasculitis in a hepatitis C patient. (23872543)
2013
3
Association of erysipelas with acute renal failure. (20508989)
2011
4
First case of erysipelas in a free-ranging bottlenose dolphin (Tursiops truncatus) stranded in the Mediterranean Sea. (22303633)
2011
5
Erysipelas-like erythema with familial Mediterranean fever. (21352275)
2011
6
Analysis of epidemiology, clinical features and management of erysipelas. (20931671)
2010
7
Blistering erysipelas: not a rare entity. (18946616)
2008
8
Erysipelas: a common potentially dangerous infection. (17994173)
2007
9
Rheological properties of erythrocytes in patients suffering from erysipelas. Examination with LORCA device. (16614462)
2006
10
Osteoarticular complications of erysipelas. (14726873)
2004
11
Antibiotic use in patients with erysipelas: a retrospective study. (11692544)
2001
12
Anal colonization of group G beta-hemolytic streptococci in relapsing erysipelas of the lower extremity. (10524984)
1999
13
Risk factors for erysipelas of the leg (cellulitis): case-control study. (10364117)
1999
14
Distant cutaneous manifestation of Crohn's disease presenting as a granulomatous erysipelas-like lesion. (10188155)
1999
15
Erysipelas--its occurrence and clinical aspects in Prague, 1993. A retrospective study. (9331609)
1997
16
Pre-septal cellulitis and facial erysipelas due to Moraxella species. (7955474)
1994
17
The red face: erysipelas. (8348445)
1993
18
Facial erysipelas: report of a case and review of the literature. (1890524)
1991
19
Prophylactic antibiotics in erysipelas. (2861358)
1985
20
An outbreak of erysipelas in chukars. (4074250)
1985
21
Serotypes of Erysipelothrix rhusiopathiae strains isolated from slaughter pigs affected with chronic erysipelas. (6748441)
1984
22
Cross protection in mice and swine immunized with live erysipelas vaccine to challenge exposure with strains of Erysipelothrix rhusiopathiae of various serotypes. (6497110)
1984
23
A report of swine erysipelas in a litter of piglets. (6533307)
1984
24
Diagnosis and successful treatment of subacute erysipelas in a captive dolphin. (6655661)
1983
25
An erysipelas-like scalp cellulitis due to haemophilus influenzae type b. (6965310)
1980
26
Erysipelas. (840657)
1977
27
Erysipelas in egg-laying chickens: clinical, pathological and bacteriological investigations. (18777293)
1975
28
Maintenance and protective effect of 131-I-labeled anti-swine erysipelas serum in blood of specific-pathogen-free piglets. (4098402)
1970
29
Problems of erysipelas. 3. Streptococcal vaccine treatment of relapsing erysipelas. (5678738)
1968
30
Vaccination of Swine with erysipelas vaccine (live culture-modified) by the oral route. (17421791)
1966
31
Chronic Erysipelothrix rhusiopathiae infection in laboratory rats. I. Attempts to produce chronic erysipelas by the injection of killed organisms. (5322918)
1965
32
HYPERSENSITIVITY IN ERYSIPELAS ARTHRITIS OF SWINE. II. HYPERSENSITIZATION OF SWINE WITH STERILE ERYSIPELOTHRIX ANTIGENS. (14103216)
1964
33
EXPERIMENTAL EVALUATION OF AN AVIRULENT ORAL ERYSIPELAS VACCINE. (14075410)
1963
34
Joint changes in swine erysipelas. (13624058)
1959
35
The mortality from Erysipelas over the last hundred years in Antigua, the West Indies. (13660000)
1958
36
An emulsion-type erysipelas bacterin. I. Duration of immunity in pigs vaccinated at weaning. (13394829)
1957
37
Laboratory studies on erysipelas. II. Use of various cultures in production of infection in pigs by skin scarification. (13283239)
1956
38
ANOTHER milestone; an immunity test for erysipelas. (13096441)
1953
39
Experimental evaluation of culture and serum vaccination for the control of swine erysipelas. IV. Gilts vaccinated with culture and serum before breeding, and its immunizing effect on their offspring. (13108805)
1953
40
Immunization of Turkeys against Swine Erysipelas with Several Types of Bacterins. (17648605)
1952
41
DIFFERENTIAL diagnosis of swine erysipelas. (20988172)
1946
42
Swine erysipelas. (20988104)
1946
43
Chemotherapy of Swine Erysipelas: Trials using Sulfanilamide, Sulfapyridine and Sulfathianzole in Experimental Infection of Mice. (17648130)
1945
44
Sulphanilamide in Erysipelas. (20781678)
1938
45
Prontosil in Erysipelas. (20780782)
1937
46
A Study of Variation in Hemolytic Streptococci from Scarlet Fever and Erysipelas: Preliminary Report. (16559673)
1933
47
Erysipelas in Children. (20317481)
1929
48
IX. Contribution to the Study of Sarcoma of the Femur: Periosteal Round-Celled Sarcoma of the Femur, Involving Two-Thirds of the Shaft, with Very Extensive Multiple Metastases-Apparent Cure by the Mixed Toxins of Erysipelas and Bacillus Prodigiosus. Well 10(1/2) Years, when a Malignant Tumor (Sarcoma and Epithelioma) Developed in the Thigh at the Site of an Old X-Ray Dermatitis. (17863042)
1913
49
On the Use of Antistreptococcus Serum in Puerperal Septicaemia and Erysipelas. (20758874)
1900
50
Erysipelas of the Pharynx and Larynx. (20753570)
1892

Genetic Variations for Erysipelas

Expression for genes affiliated with Erysipelas

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Erysipelas

Search GEO for disease gene expression data for Erysipelas.

Pathways for genes affiliated with Erysipelas

Compounds for genes affiliated with Erysipelas

Sources:
45Novoseek, 11DrugBank, 50PharmGKB, 29IUPHAR, 24HMDB, 60Tocris Bioscience, 2BitterDB
See all sources

Compounds related to Erysipelas according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1hydroxychloroquine45 1111.0CD40LG, TNF
2blys4510.0CD40LG, TNF
3silicone459.8ELN, CD40LG
4okt3459.8ELN, CD40LG, TNF
5fenofibrate45 50 1111.7CD40LG, PIK3C2A, TNF
6atorvastatin45 50 29 11 2413.6TNF, PIK3C2A, CD40LG
7histamine45 29 2411.5TNF, PI3, CD40LG, ELN
8superoxide45 2410.5PI3, TNF, AZU1
9il-12459.5CD40LG, TNF
10ivig459.4ELN, CD40LG, PIK3C2A, TNF
11fibrinogen459.4TNF, PIK3C2A, CD40LG, ELN
12hyaluronic acid45 2410.3AZU1, CD40LG, ELN
13cyclosporin a45 29 6011.3TNF, PI3, PIK3C2A, CD40LG
14endotoxin459.3AZU1, TNF, MEFV, CD40LG
15lactate459.2TNF, PIK3C2A, CD40LG, ELN
16actinomycin d459.1BDKRB1, TNF, CD40LG, ELN
17genistein45 29 60 2 11 2414.1ELN, CD40LG, TNF, BDKRB1
18vegf458.8ELN, CD40LG, PIK3C2A, TNF, AZU1
19heparin45 29 11 2411.8ELN, CD40LG, PIK3C2A, AZU1
20retinoic acid45 249.7ELN, CD40LG, PI3, TNF, AZU1
21serine458.5AZU1, TNF, PHGDH, PI3, CD40LG, ELN

GO Terms for genes affiliated with Erysipelas

Sources:
16Gene Ontology
See all sources

Biological processes related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of immunoglobulin secretionGO:0510239.8CD40LG, TNF
2inflammatory responseGO:0069548.0CD40LG, MEFV, TNF, BDKRB1, AZU1

Molecular functions related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.8CD40LG, TNF

Products for genes affiliated with Erysipelas

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Erysipelas

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet