MCID: ERY004
MIFTS: 42

Erysipelas malady

Rare diseases, Infectious diseases categories

Aliases & Classifications for Erysipelas

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Aliases & Descriptions for Erysipelas:

Name: Erysipelas 8 42 10 44 61


Classifications:



External Ids:

Disease Ontology8 DOID:11330
ICD9CM27 035
MeSH33 D004886
ICD1025 A46

Summaries for Erysipelas

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Wikipedia:64 Erysipelas (/?r??s?p?l?s/; Greek ???????????red skin; also known as \"Ignis sacer\", \"holy fire\", and... more...

MalaCards based summary: Erysipelas is related to familial mediterranean fever, ar and pneumonia. An important gene associated with Erysipelas is PI3 (peptidase inhibitor 3, skin-derived), and among its related pathways are Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways and NF-kappa B signaling pathway. The compounds silicone and glutaraldehyde have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and breast, and related mouse phenotypes are integument and skeleton.

Related Diseases for Erysipelas

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Diseases related to Erysipelas via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 95)
idRelated DiseaseScoreTop Affiliating Genes
1familial mediterranean fever, ar30.3TNF, MEFV
2pneumonia30.0PI3, TNF, PIK3C2A
3vasculitis30.0MEFV, TNF, CD40LG
4skin disease29.8ELN, TNF, PI3
5ischemia29.8PIK3C2A, BDKRB1, AZU1
6hepatitis c29.5CD40LG, TNF
7cellulitis10.7
8arthritis10.5
9calcinosis10.4PIK3C2A
10palindromic rheumatism10.4MEFV
11lymphedema10.4
12polyarteritis nodosa10.3MEFV
13erysipeloid10.3
14breast cancer10.3
15fasciitis10.3
16schnitzler syndrome10.3CD40LG
17hemorrhagic fever10.3CD40LG
18scrub typhus10.2CD40LG
19necrotizing fasciitis10.2
20scarlet fever10.2
21acute respiratory distress syndrome10.2PI3, TNF
22periodic fever, familial10.2MEFV, TNF
23lupus erythematosus10.2
24discoid lupus erythematosus10.2
25blau syndrome10.2MEFV, TNF
26respiratory failure10.1TNF, PIK3C2A
27bacteremia10.1
28mycosis fungoides10.1
29cholera10.1
30lymphangitis10.1
31tinea pedis10.1
32dermatitis10.1
33elephantiasis10.1
34influenza10.1
35myocarditis10.1
36sarcoma10.1
37hennekam syndrome10.1
38st anthony's fire10.1
39tumor necrosis factor receptor 1 associated periodic syndrome10.1
40leptospirosis10.1CD40LG, PIK3C2A
41behcet's disease10.1TNF, MEFV
42dengue disease10.0CD40LG, PIK3C2A
43peritonitis10.0TNF, AZU1, MEFV
44pulmonary disease, chronic obstructive10.0ELN, TNF, PI3
45cork-handlers' disease10.0ELN, PI3, TNF
46spondyloarthropathy 110.0TNF, CD40LG
47vascular disease9.9ELN, PIK3C2A, TNF
48microcephaly with or without chorioretinopathy, lymphedema, or mental retardation9.9
49poikiloderma, hereditary fibrosing, with tendon contractures, myopathy, and pulmonary fibrosis9.9
50cholestasis-lymphedema syndrome9.9

Graphical network of the top 20 diseases related to Erysipelas:



Diseases related to erysipelas

Symptoms for Erysipelas

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Drugs & Therapeutics for Erysipelas

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Drug clinical trials:

Search ClinicalTrials for Erysipelas

Search NIH Clinical Center for Erysipelas

Genetic Tests for Erysipelas

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Anatomical Context for Erysipelas

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MalaCards organs/tissues related to Erysipelas:

31
Skin, Testes, Breast, Colon, Eye, Bone, Lymph node, Spleen, Retina, Heart, Thyroid, Monocytes, B cells, Pituitary, Neutrophil

Animal Models for Erysipelas or affiliated genes

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MGI Mouse Phenotypes related to Erysipelas:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.6BDKRB1, CD40LG, MEFV, TNF
2MP:00053908.4TNF, ELN, MEFV, CD40LG
3MP:00053877.9PIK3C2A, TNF, MEFV, CD40LG, BDKRB1
4MP:00053767.6BDKRB1, CD40LG, MEFV, ELN, TNF, PIK3C2A
5MP:00107687.6PIK3C2A, TNF, ELN, MEFV, CD40LG, BDKRB1

Publications for Erysipelas

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Articles related to Erysipelas:

(show top 50)    (show all 503)
idTitleAuthorsYear
1
Erysipelothrix rhusiopathiae contamination in the poultry house environment during erysipelas outbreaks in organic laying hen flocks. (24661145)
2014
2
Erysipelas-like Erythema in a Patient with Familial Mediterranean Fever. (25362709)
2014
3
Prevalence of Met-203 type spaA variant in Erysipelothrix rhusiopathiae isolates and the efficacy of swine erysipelas vaccines in Japan. (24405986)
2014
4
Erysipelas in a free-range layer flock with conjunctival oedema as an unusual clinical sign. (24881267)
2014
5
Risk of deep vein thrombosis in patients with cellulitis and erysipelas: a systematic review and meta-analysis. (23948644)
2013
6
The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of firmicutes and the organism's intracellular adaptations. (21478354)
2011
7
Characterization of Erysipelothrix species isolates from clinically affected pigs, environmental samples, and vaccine strains from six recent swine erysipelas outbreaks in the United States. (20719987)
2010
8
Erysipelas: a common potentially dangerous infection. (17994173)
2007
9
Risk factors for erysipelas of the leg in Tunisia: a multicenter case-control study. (16484815)
2006
10
A blistering disease: bullous erysipelas. (16880441)
2006
11
Oedema as a risk factor for multiple episodes of cellulitis/erysipelas of the lower leg: a series with community follow-up. (17034523)
2006
12
Bullous erysipelas: clinical presentation, staphylococcal involvement and methicillin resistance. (16319471)
2006
13
Erysipelas after breast cancer treatment (26 cases). (16409908)
2005
14
Wound healing of chronic leg ulcers under the influence of erysipelas. (14965798)
2004
15
Cellulitis and erysipelas. (15865787)
2004
16
Oral pristinamycin versus standard penicillin regimen to treat erysipelas in adults: randomised, non-inferiority, open trial. (12386036)
2002
17
Lymphoscintigraphic evaluation in patients after erysipelas. (11191659)
2000
18
Erysipelas and tinea pedis. (10948816)
2000
19
Erysipelas in malleefowl. (10451726)
1999
20
Erysipelas: clinical and bacteriologic spectrum and serological aspects. (8922808)
1996
21
St. Anthony's fire: an eponym for ergotism, not erysipelas. (7604780)
1995
22
Pre-septal cellulitis and facial erysipelas due to Moraxella species. (7955474)
1994
23
Streptococcal arthritis and erysipelas complicating dental extraction. (8422570)
1993
24
Facial erysipelas: report of a case and review of the literature. (1890524)
1991
25
Erysipelas. (2228369)
1990
26
Erysipelas complicating chronic discoid lupus erythematosus of the face--a case report and review of erysipelas. (2680180)
1989
27
Study of granulocyte function of peripheral blood in recurrent erysipelas. (2612708)
1989
28
Lucigenin-amplified chemiluminescence in blood and synovial fluid phagocytes of pigs with erysipelas arthritis. (4096165)
1985
29
Prophylactic antibiotics in recurrent erysipelas. (2857399)
1985
30
Serotypes of Erysipelothrix rhusiopathiae strains isolated from slaughter pigs affected with chronic erysipelas. (6748441)
1984
31
Septic prepatellar bursitis due to erysipelas. (7306248)
1981
32
In defense of erysipelas vaccine. (7364625)
1980
33
Granulomatous lesions in pigs associated with the use of an oil-based erysipelas vaccine. (614024)
1977
34
The histochemistry of prefascial lymph vessels in recurrent erysipelas. (4148228)
1973
35
Leukocyte migration test in recurrent erysipelas. (4120805)
1973
36
Triple sugar iron agar as an aid in the diagnosis of erysipelas. (13598680)
1958
37
Modified Swine Erysipelas Vaccine. (17649050)
1958
38
The incidence of arthritis in swine following vaccination for swine erysipelas. (13498229)
1958
39
Experimental evaluation of culture and serum vaccination for the control of swine erysipelas. V. Vaccination of weanling pigs using a change in the dosage relationship of culture and serum. (13201496)
1954
40
Studies of Swine Erysipelas. II. Cultural Characteristics and Virulence of Strains of Erysipelothrix Rhusiopathiae Isolated in Canada. (17648553)
1952
41
Erysipelas in turkeys; a case report. (18124860)
1949
42
DIFFERENTIAL diagnosis of swine erysipelas. (20988172)
1946
43
SPECIES SPECIFIC IMMUNITY TO HEMOLYTIC STREPTOCOCCUS INFECTIONS INDUCED IN WHITE MICE BY IMMUNIZATION WITH AN R VARIANT OF AN ERYSIPELAS STRAIN : The Significance of Cell Autolysis in Relation to Antibody Response. (16560103)
1938
44
Erysipelas. (18744161)
1937
45
The Statistics of Erysipelas in England and Wales. (20475199)
1933
46
Relationship of the Streptococci Causing Erysipelas. (18012891)
1929
47
Syphilitic Meningo-Myelitis: Erysipelas: Recovery. (20759725)
1901
48
Seasonable Influences in Erysipelas, with Statistics. (21409070)
1895
49
A Case of Erysipelas Neonatorum Treated by Antistreptococcic Serum. (20755865)
1895
50
Vitiligo as a Sequela of Influenza and Erysipelas. (20753304)
1891

Variations for Erysipelas

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Expression for genes affiliated with Erysipelas

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Search GEO for disease gene expression data for Erysipelas.

Pathways for genes affiliated with Erysipelas

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Pathways related to Erysipelas according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6MEFV, TNF
29.5CD40LG, TNF
3
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
9.5CD40LG, TNF
4
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway59
9.5CD40LG, TNF
59.5CD40LG, TNF
6
Show member pathways
9.3PIK3C2A, TNF

Compounds for genes affiliated with Erysipelas

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Compounds related to Erysipelas according to GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1silicone4410.0ELN, CD40LG
2glutaraldehyde449.9ELN, CD40LG
3blys449.9CD40LG, TNF
4hydroxychloroquine44 1110.9TNF, CD40LG
5il-12449.9TNF, CD40LG
6lactose44 1110.8ELN, CD40LG
7sulfasalazine28 44 50 1112.8TNF, CD40LG
8doxycycline44 1110.8CD40LG, ELN
9mycophenolate mofetil44 50 1111.8TNF, CD40LG
10hirudin449.7PIK3C2A, CD40LG
11erythromycin44 1 50 1112.6PIK3C2A, CD40LG
12neopterin449.6TNF, CD40LG
13okt3449.5ELN, CD40LG, TNF
14theophylline44 28 24 1112.5CD40LG, ELN
15melphalan44 50 1111.5TNF, PIK3C2A
16rituximab44 50 1111.5CD40LG, TNF
17dermatan sulfate449.5AZU1, ELN
18n acetylcysteine449.5CD40LG, ELN, TNF
19indomethacin44 28 60 1112.4TNF, CD40LG, ELN
20sb 20358044 6010.4PI3, BDKRB1, TNF
21ascorbic acid44 2410.3ELN, CD40LG, PIK3C2A
22thromboxane a244 2410.3BDKRB1, PIK3C2A
23fenofibrate44 50 1111.3PIK3C2A, TNF, CD40LG
24atorvastatin44 50 28 24 1113.3PIK3C2A, CD40LG, TNF
25ly294002449.3PIK3C2A, TNF, PI3
26hyaluronic acid44 2410.2CD40LG, ELN, AZU1
27histamine44 28 2411.2CD40LG, PI3, TNF, ELN
28dexamethasone44 50 28 1112.1CD40LG, PI3, ELN, TNF
29creatinine449.1CD40LG, ELN, PIK3C2A
30polysaccharide449.1ELN, CD40LG, AZU1
31aspartate449.1CD40LG, ELN, PIK3C2A
32actinomycin d449.0CD40LG, TNF, ELN, BDKRB1
33genistein44 28 60 1 24 1114.0TNF, ELN, BDKRB1, CD40LG
34cyclosporin a44 28 6011.0CD40LG, TNF, PIK3C2A, PI3
35ivig448.9ELN, TNF, PIK3C2A, CD40LG
36fibrinogen448.9CD40LG, TNF, PIK3C2A, ELN
37lactate448.9PIK3C2A, TNF, ELN, CD40LG
38endotoxin448.8TNF, MEFV, CD40LG, AZU1
39cycloheximide448.7BDKRB1, ELN, TNF
40superoxide44 249.6AZU1, PI3, TNF, PIK3C2A
41heparin44 28 24 1111.6CD40LG, AZU1, ELN, PIK3C2A
42arginine448.6AZU1, PIK3C2A, ELN, CD40LG
43glutamate448.5AZU1, ELN, PIK3C2A, CD40LG
44oxygen44 249.5TNF, PIK3C2A, AZU1, PI3
45lipid448.4TNF, PIK3C2A, PI3, AZU1
46retinoic acid44 249.4ELN, TNF, PI3, AZU1, CD40LG
47serine448.3CD40LG, PI3, ELN, AZU1, TNF
48tyrosine448.2PIK3C2A, MEFV, BDKRB1, AZU1, PI3
49vegf448.1AZU1, PIK3C2A, TNF, ELN, CD40LG
50calcium44 50 24 1111.1PIK3C2A, ELN, AZU1, PI3, BDKRB1

GO Terms for genes affiliated with Erysipelas

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Biological processes related to Erysipelas according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1organ morphogenesisGO:00098879.5ELN, TNF
2regulation of immunoglobulin secretionGO:00510239.5TNF, CD40LG
3response to mechanical stimulusGO:00096129.1BDKRB1, TNF
4protein kinase C-activating G-protein coupled receptor signaling pathwayGO:00072059.0BDKRB1, AZU1
5inflammatory responseGO:00069547.8BDKRB1, CD40LG, MEFV, TNF, AZU1

Molecular functions related to Erysipelas according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:00051649.5CD40LG, TNF

Sources for Erysipelas

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet