MCID: ERY004
MIFTS: 43

Erysipelas malady

Infectious diseases category

Summaries for Erysipelas

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63Wikipedia, 32MalaCards
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Wikipedia:63 Erysipelas (/ɛrɨˈsɪpələs/; Greek ἐρυσίπελας—red skin; also known as \"Ignis sacer\",... more...

MalaCards: Erysipelas is related to familial mediterranean fever and necrotizing fasciitis. An important gene associated with Erysipelas is PI3 (peptidase inhibitor 3, skin-derived). The compounds hydroxychloroquine and blys have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and breast, and related mouse phenotype mortality/aging.

Aliases & Classifications for Erysipelas

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8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 60UMLS, 27ICD9CM, 34MeSH, 56SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

erysipelas 8 42 10 44 60


External Ids:

Disease Ontology8 DOID:11330
ICD9CM27 035
MeSH34 D004886
ICD1025 A46

Related Diseases for Erysipelas

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17GeneCards, 18GeneDecks
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Diseases related to Erysipelas via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 104)
idRelated DiseaseScoreTop Affiliating Genes
1familial mediterranean fever30.3TNF, MEFV
2necrotizing fasciitis30.2SPEG
3vasculitis30.1CD40LG, MEFV, TNF
4dermatitis30.0PIK3C2A
5myotonic dystrophy29.8PIK3C2A
6crohn's disease29.8TNF
7pharyngitis29.8SPEG
8ischemia29.8PIK3C2A, BDKRB1, AZU1
9pneumonia29.8PIK3C2A, PI3, TNF
10skin disease29.7TNF, PI3, ELN
11cellulitis10.6
12arthritis10.5
13lymphedema10.3
14erysipeloid10.3
15breast cancer10.2
16fasciitis10.2
17scarlet fever10.2
18lupus erythematosus10.1
19cholera10.0
20lymphangitis10.0
21mycosis fungoides10.0
22tinea pedis10.0
23elephantiasis10.0
24influenza10.0
25sarcoma10.0
26myocardial infarction10.0PIK3C2A
27diphtheria10.0AZU1
28hyperuricemia10.0PIK3C2A
29disseminated intravascular coagulation10.0PIK3C2A
30pyoderma gangrenosum10.0MEFV
31pericarditis10.0MEFV
32brucellosis10.0MEFV
33palindromic rheumatism10.0MEFV
34primary hyperoxaluria10.0TNF
35polyarteritis nodosa10.0MEFV
36galactosemia10.0TNF
37amyloidosis10.0MEFV
38acute myocardial infarction10.0MEFV, PIK3C2A
39autoimmune hemolytic anemia10.0CD40LG
40schnitzler syndrome10.0CD40LG
41endometriosis10.0ELN
42antiphospholipid syndrome10.0CD40LG
43schistosomiasis10.0CD40LG
44tumor necrosis factor receptor-associated periodic syndrome10.0TNF, MEFV
45multiple sclerosis10.0TNF
46toxic shock syndrome10.0SPEG, TNF
47tetanus10.0CD40LG
48blau syndrome10.0MEFV, TNF
49periodontal disease10.0TNF
50leptospirosis10.0PIK3C2A, CD40LG

Graphical network of the top 20 diseases related to Erysipelas:



Diseases related to erysipelas

Clinical Features for Erysipelas

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Drugs & Therapeutics for Erysipelas

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Erysipelas

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Anatomical Context for Erysipelas

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32MalaCards
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MalaCards organs/tissues related to Erysipelas:

32
Skin, Testes, Breast, Colon, Eye, B cells, Monocytes, Thyroid, Heart, Retina, Spleen, Lymph node, Bone, Pituitary

Animal Models for Erysipelas or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Erysipelas:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107687.3ELN, SPEG, CD40LG, MEFV, PIK3C2A, PHGDH

Publications for Erysipelas

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50PubMed
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Articles related to Erysipelas:

(show top 50)    (show all 491)
idTitleAuthorsYear
1
Erysipelas-like erythema as the presenting feature of familial Mediterranean fever. (22243424)
2013
2
A case of diffuse large B-cell lymphoma misdiagnosed as an erysipelas of the face. (24278087)
2013
3
Recurrent erysipelas secondary to a late prosthetic femoropopliteal bypass infection. (22377936)
2013
4
The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of firmicutes and the organism's intracellular adaptations. (21478354)
2011
5
Hypertriglyceridemic pancreatitis in infant with erysipelas. (22067359)
2011
6
Epidemiological data and comorbidities of 428 patients hospitalized with erysipelas. (20147345)
2010
7
Cellulitis and erysipelas. (19450336)
2008
8
Mycosis fungoides mimicking erysipelas. (18248497)
2008
9
Erysipelas-like inflammation following breast surgery. (17399657)
2007
10
Erysipelas of the left upper limb occurring after elbow dislocation. (17083864)
2006
11
Oral vaccination against swine erysipelas--field experiences in Croatia. (16475549)
2006
12
Oral pristinamycin versus standard penicillin regimen to treat erysipelas in adults: randomised, non-inferiority, open trial. (12386036)
2002
13
The CD14+CD16+ monocytes in erysipelas are expanded and show reduced cytokine production. (11981819)
2002
14
Erysipelas-like erythema of familial Mediterranean fever: clinicopathologic correlation. (10775856)
2000
15
Erysipelas in a free-ranging Hawaiian crow (Corvus hawaiiensis). (10396650)
1999
16
Treatment and control by vaccination of erysipelas in farmed emus (Dromaius novohollandiae). (9631698)
1998
17
An outbreak of urticarial form of swine erysipelas in a medium-scale piggery in Kiambu District, Kenya. (9760400)
1998
18
Erysipelas. (2228369)
1990
19
Comparison of inoculation regimes for the experimental production of swine erysipelas arthritis. I. Clinical, pathological and bacteriological findings. (2775064)
1989
20
Actinobacillus suis septicemia in mature swine: two outbreaks resembling erysipelas. (17423473)
1989
21
Cartilage destruction mechanisms: initial changes in the proteoglycan pattern in Erysipelas arthritis of pigs in vivo and chondrocyte repair reaction in vitro. (3354384)
1988
22
Epidemiological, bacteriological and complicating features of erysipelas. (3810046)
1986
23
The value of bacteriology and serology in the diagnosis of cellulitis and erysipelas. (4005155)
1985
24
Erysipelas after venectomy for coronary artery bypass surgery. (6607240)
1983
25
Idiopathic erysipelas. A case presentation. (7054264)
1982
26
Septic prepatellar bursitis due to erysipelas. (7306248)
1981
27
Facial erysipelas in the immunocompromised host. Report of two cases. (7458384)
1981
28
Effect of antibiotics on the immune system of animals. III. Experiments in pgis immunized with live and inactivated swine erysipelas vaccines. (7258020)
1981
29
An improved quantitative method for the study of fibrinolysis in the skin as exemplified in patients with leukocytoclastic vasculitis and erysipelas. (6163272)
1980
30
Necrotizing erysipelas of the eyelids. (453744)
1979
31
The erysipelas problem. II. The properties and aetiological role of streptococcus strains isolated from erysipelas and other dermal diseases. (5600728)
1967
32
HYPERSENSITIVITY IN ERYSIPELAS ARTHRITIS OF SWINE. III. PASSIVE TRANSFER OF HYPERSENSITIVITY WITH IMMUNE SERUM. (14103217)
1964
33
Present status of prophylactic vaccination in swine erysipelas. (13538894)
1958
34
Erysipelas-like lesions of the lower extremities. (13564127)
1958
35
Control of an erysipelas outbreak in turkeys with a bacterin. (13295128)
1956
36
Tinea pedis and relapsing erysipelas. (13306015)
1956
37
Swine Immunity With Erysipelas Bacterin. (17648883)
1956
38
Erysipelas vaccine avirulent (EVA) a new agent for erysipelas control. (13271238)
1955
39
Studies on arthritis in swine. I. Experimental erysipelas and chronic arthritis in swine. (13238735)
1955
40
Two cases of erysipelas in the white Pekin duck. (13150762)
1954
41
Studies of Swine Erysipelas. II. Cultural Characteristics and Virulence of Strains of Erysipelothrix Rhusiopathiae Isolated in Canada. (17648553)
1952
42
Studies of Swine Erysipelas. IV. Serological Diagnosis in Swine. (17648571)
1952
43
An improved swine erysipelas vaccine: a review of recent developments by European investigators. (14936440)
1952
44
The efficacy of penicillin and 2-sulfanilamido-5-methyl-1,3,4, thiodiazole (lucosil) in the treatment of erysipelas. (14837702)
1951
45
Swine erysipelas infection in man. (18904103)
1948
46
Chronic erysipeloid (swine erysipelas) in a man; the effect of treatment with penicillin. (20251976)
1947
47
SPECIES SPECIFIC IMMUNITY TO HEMOLYTIC STREPTOCOCCUS INFECTIONS INDUCED IN WHITE MICE BY IMMUNIZATION WITH AN R VARIANT OF AN ERYSIPELAS STRAIN : The Significance of Cell Autolysis in Relation to Antibody Response. (16560103)
1938
48
TREATMENT OF ERYSIPELAS BY INJECTIONS OF MILK. (20776673)
1932
49
Antistreptococcus Serum in Erysipelas. (20759090)
1900
50
Erysipelas and Vaccination. (20748898)
1878

Genetic Variations for Erysipelas

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Expression for genes affiliated with Erysipelas

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Erysipelas

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Pathways for genes affiliated with Erysipelas

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Compounds for genes affiliated with Erysipelas

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44Novoseek, 11DrugBank, 49PharmGKB, 28IUPHAR, 24HMDB, 59Tocris Bioscience, 2BitterDB
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Compounds related to Erysipelas according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1hydroxychloroquine44 1111.0CD40LG, TNF
2blys4410.0CD40LG, TNF
3silicone449.8ELN, CD40LG
4okt3449.8ELN, CD40LG, TNF
5fenofibrate44 49 1111.7CD40LG, PIK3C2A, TNF
6atorvastatin44 49 28 11 2413.6TNF, PIK3C2A, CD40LG
7histamine44 28 2411.5TNF, PI3, CD40LG, ELN
8superoxide44 2410.5PI3, TNF, AZU1
9il-12449.5CD40LG, TNF
10ivig449.4ELN, CD40LG, PIK3C2A, TNF
11fibrinogen449.4TNF, PIK3C2A, CD40LG, ELN
12hyaluronic acid44 2410.3AZU1, CD40LG, ELN
13cyclosporin a44 28 5911.3TNF, PI3, PIK3C2A, CD40LG
14endotoxin449.3AZU1, TNF, MEFV, CD40LG
15lactate449.2TNF, PIK3C2A, CD40LG, ELN
16actinomycin d449.1BDKRB1, TNF, CD40LG, ELN
17genistein44 28 59 2 11 2414.1ELN, CD40LG, TNF, BDKRB1
18vegf448.8ELN, CD40LG, PIK3C2A, TNF, AZU1
19heparin44 28 11 2411.8ELN, CD40LG, PIK3C2A, AZU1
20retinoic acid44 249.7ELN, CD40LG, PI3, TNF, AZU1
21serine448.5AZU1, TNF, PHGDH, PI3, CD40LG, ELN

GO Terms for genes affiliated with Erysipelas

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16Gene Ontology
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Biological processes related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of immunoglobulin secretionGO:0510239.8CD40LG, TNF
2inflammatory responseGO:0069548.0CD40LG, MEFV, TNF, BDKRB1, AZU1

Molecular functions related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.8CD40LG, TNF

Products for genes affiliated with Erysipelas

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Erysipelas

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet