MCID: ERY004
MIFTS: 49

Erysipelas malady

Rare diseases, Infectious diseases categories

Summaries for Erysipelas

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Wikipedia:65 Erysipelas (/?r??s?p?l?s/; Greek ???????????red skin; also known as \"Ignis sacer\", \"holy fire\", and... more...

MalaCards based summary: Erysipelas is related to vasculitis and familial mediterranean fever, ar. An important gene associated with Erysipelas is PI3 (peptidase inhibitor 3, skin-derived), and among its related pathways are Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways and NF-kappa B signaling pathway. The compounds silicone and glutaraldehyde have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and breast, and related mouse phenotypes are integument and skeleton.

Aliases & Classifications for Erysipelas

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Erysipelas, Aliases & Descriptions:

Name: Erysipelas 10 43 12 45 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases


External Ids:

Disease Ontology10 DOID:11330
ICD9CM29 035
MeSH35 D004886
ICD1027 A46

Related Diseases for Erysipelas

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Diseases related to Erysipelas via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 95)
idRelated DiseaseScoreTop Affiliating Genes
1vasculitis30.2CD40LG, MEFV, TNF
2familial mediterranean fever, ar30.1MEFV, TNF
3pneumonia29.9TNF, PIK3C2A, PI3
4skin disease29.9PI3, TNF, ELN
5ischemia29.9BDKRB1, PIK3C2A, AZU1
6hepatitis c29.8CD40LG, TNF
7cellulitis10.7
8arthritis10.5
9lymphedema10.4
10erysipeloid10.3
11breast cancer10.3
12fasciitis10.3
13necrotizing fasciitis10.2
14scarlet fever10.2
15lupus erythematosus10.2
16discoid lupus erythematosus10.2
17bacteremia10.1
18mycosis fungoides10.1
19cholera10.1
20lymphangitis10.1
21tinea pedis10.1
22dermatitis10.1
23elephantiasis10.1
24influenza10.1
25myocarditis10.1
26sarcoma10.1
27hennekam syndrome10.1
28st anthony's fire10.1
29tumor necrosis factor receptor 1 associated periodic syndrome10.1
30calcinosis10.0PIK3C2A
31palindromic rheumatism10.0MEFV
32polyarteritis nodosa10.0MEFV
33schnitzler syndrome10.0CD40LG
34hemorrhagic fever10.0CD40LG
35scrub typhus10.0CD40LG
36acute respiratory distress syndrome10.0TNF, PI3
37periodic fever, familial10.0TNF, MEFV
38blau syndrome10.0MEFV, TNF
39respiratory failure10.0PIK3C2A, TNF
40leptospirosis10.0PIK3C2A, CD40LG
41behcet's disease10.0MEFV, TNF
42dengue disease10.0CD40LG, PIK3C2A
43peritonitis10.0MEFV, TNF, AZU1
44pulmonary disease, chronic obstructive10.0ELN, TNF, PI3
45cork-handlers' disease10.0ELN, TNF, PI3
46spondyloarthropathy 110.0CD40LG, TNF
47vascular disease10.0ELN, TNF, PIK3C2A
48thrombocytopenia10.0AZU1, PIK3C2A, CD40LG
49iga glomerulonephritis10.0MEFV, CD40LG
50connective tissue disease10.0TNF, CD40LG

Graphical network of the top 20 diseases related to Erysipelas:



Diseases related to erysipelas

Symptoms for Erysipelas

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Drugs & Therapeutics for Erysipelas

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Drug clinical trials:

Search ClinicalTrials for Erysipelas

Search NIH Clinical Center for Erysipelas

Genetic Tests for Erysipelas

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Anatomical Context for Erysipelas

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MalaCards organs/tissues related to Erysipelas:

33
Skin, Testes, Breast, Colon, Eye, Bone, Lymph node, Spleen, Retina, Heart, Thyroid, Monocytes, B cells, Pituitary, Neutrophil

Animal Models for Erysipelas or affiliated genes

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MGI Mouse Phenotypes related to Erysipelas:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.6BDKRB1, CD40LG, MEFV, TNF
2MP:00053908.4TNF, ELN, MEFV, CD40LG
3MP:00053877.9PIK3C2A, TNF, MEFV, CD40LG, BDKRB1
4MP:00053767.6BDKRB1, CD40LG, MEFV, ELN, TNF, PIK3C2A
5MP:00107687.6PIK3C2A, TNF, ELN, MEFV, CD40LG, BDKRB1

Publications for Erysipelas

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Articles related to Erysipelas:

(show top 50)    (show all 503)
idTitleAuthorsYear
1
Erysipelothrix rhusiopathiae contamination in the poultry house environment during erysipelas outbreaks in organic laying hen flocks. (24661145)
2014
2
Erysipelas-like Erythema in a Patient with Familial Mediterranean Fever. (25362709)
2014
3
Prevalence of Met-203 type spaA variant in Erysipelothrix rhusiopathiae isolates and the efficacy of swine erysipelas vaccines in Japan. (24405986)
2014
4
Erysipelas in a free-range layer flock with conjunctival oedema as an unusual clinical sign. (24881267)
2014
5
Risk of deep vein thrombosis in patients with cellulitis and erysipelas: a systematic review and meta-analysis. (23948644)
2013
6
The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of firmicutes and the organism's intracellular adaptations. (21478354)
2011
7
Characterization of Erysipelothrix species isolates from clinically affected pigs, environmental samples, and vaccine strains from six recent swine erysipelas outbreaks in the United States. (20719987)
2010
8
Erysipelas: a common potentially dangerous infection. (17994173)
2007
9
Risk factors for erysipelas of the leg in Tunisia: a multicenter case-control study. (16484815)
2006
10
A blistering disease: bullous erysipelas. (16880441)
2006
11
Oedema as a risk factor for multiple episodes of cellulitis/erysipelas of the lower leg: a series with community follow-up. (17034523)
2006
12
Bullous erysipelas: clinical presentation, staphylococcal involvement and methicillin resistance. (16319471)
2006
13
Erysipelas after breast cancer treatment (26 cases). (16409908)
2005
14
Wound healing of chronic leg ulcers under the influence of erysipelas. (14965798)
2004
15
Cellulitis and erysipelas. (15865787)
2004
16
Oral pristinamycin versus standard penicillin regimen to treat erysipelas in adults: randomised, non-inferiority, open trial. (12386036)
2002
17
Lymphoscintigraphic evaluation in patients after erysipelas. (11191659)
2000
18
Erysipelas and tinea pedis. (10948816)
2000
19
Erysipelas in malleefowl. (10451726)
1999
20
Erysipelas: clinical and bacteriologic spectrum and serological aspects. (8922808)
1996
21
St. Anthony's fire: an eponym for ergotism, not erysipelas. (7604780)
1995
22
Pre-septal cellulitis and facial erysipelas due to Moraxella species. (7955474)
1994
23
Streptococcal arthritis and erysipelas complicating dental extraction. (8422570)
1993
24
Facial erysipelas: report of a case and review of the literature. (1890524)
1991
25
Erysipelas. (2228369)
1990
26
Erysipelas complicating chronic discoid lupus erythematosus of the face--a case report and review of erysipelas. (2680180)
1989
27
Study of granulocyte function of peripheral blood in recurrent erysipelas. (2612708)
1989
28
Lucigenin-amplified chemiluminescence in blood and synovial fluid phagocytes of pigs with erysipelas arthritis. (4096165)
1985
29
Prophylactic antibiotics in recurrent erysipelas. (2857399)
1985
30
Serotypes of Erysipelothrix rhusiopathiae strains isolated from slaughter pigs affected with chronic erysipelas. (6748441)
1984
31
Septic prepatellar bursitis due to erysipelas. (7306248)
1981
32
In defense of erysipelas vaccine. (7364625)
1980
33
Granulomatous lesions in pigs associated with the use of an oil-based erysipelas vaccine. (614024)
1977
34
The histochemistry of prefascial lymph vessels in recurrent erysipelas. (4148228)
1973
35
Leukocyte migration test in recurrent erysipelas. (4120805)
1973
36
Triple sugar iron agar as an aid in the diagnosis of erysipelas. (13598680)
1958
37
Modified Swine Erysipelas Vaccine. (17649050)
1958
38
The incidence of arthritis in swine following vaccination for swine erysipelas. (13498229)
1958
39
Experimental evaluation of culture and serum vaccination for the control of swine erysipelas. V. Vaccination of weanling pigs using a change in the dosage relationship of culture and serum. (13201496)
1954
40
Studies of Swine Erysipelas. II. Cultural Characteristics and Virulence of Strains of Erysipelothrix Rhusiopathiae Isolated in Canada. (17648553)
1952
41
Erysipelas in turkeys; a case report. (18124860)
1949
42
DIFFERENTIAL diagnosis of swine erysipelas. (20988172)
1946
43
SPECIES SPECIFIC IMMUNITY TO HEMOLYTIC STREPTOCOCCUS INFECTIONS INDUCED IN WHITE MICE BY IMMUNIZATION WITH AN R VARIANT OF AN ERYSIPELAS STRAIN : The Significance of Cell Autolysis in Relation to Antibody Response. (16560103)
1938
44
Erysipelas. (18744161)
1937
45
The Statistics of Erysipelas in England and Wales. (20475199)
1933
46
Relationship of the Streptococci Causing Erysipelas. (18012891)
1929
47
Syphilitic Meningo-Myelitis: Erysipelas: Recovery. (20759725)
1901
48
Seasonable Influences in Erysipelas, with Statistics. (21409070)
1895
49
A Case of Erysipelas Neonatorum Treated by Antistreptococcic Serum. (20755865)
1895
50
Vitiligo as a Sequela of Influenza and Erysipelas. (20753304)
1891

Variations for Erysipelas

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Expression for genes affiliated with Erysipelas

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Search GEO for disease gene expression data for Erysipelas.

Pathways for genes affiliated with Erysipelas

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Pathways related to Erysipelas according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6MEFV, TNF
29.5CD40LG, TNF
3
Show member pathways
Calcium signaling in the CD4+ TCR pathway38
9.5CD40LG, TNF
4
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway60
9.5CD40LG, TNF
59.5CD40LG, TNF
6
Show member pathways
9.3PIK3C2A, TNF

Compounds for genes affiliated with Erysipelas

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Compounds related to Erysipelas according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1silicone4510.0ELN, CD40LG
2glutaraldehyde459.9ELN, CD40LG
3hydroxychloroquine45 1310.9TNF, CD40LG
4blys459.9TNF, CD40LG
5il-12459.9CD40LG, TNF
6lactose45 1310.8CD40LG, ELN
7sulfasalazine30 45 51 1312.8CD40LG, TNF
8doxycycline45 1310.8ELN, CD40LG
9mycophenolate mofetil45 51 1311.8CD40LG, TNF
10hirudin459.7PIK3C2A, CD40LG
11erythromycin45 3 51 1312.6CD40LG, PIK3C2A
12neopterin459.6TNF, CD40LG
13okt3459.5TNF, ELN, CD40LG
14theophylline45 30 26 1312.5CD40LG, ELN
15melphalan45 51 1311.5TNF, PIK3C2A
16rituximab45 51 1311.5CD40LG, TNF
17dermatan sulfate459.5ELN, AZU1
18n acetylcysteine459.5CD40LG, ELN, TNF
19indomethacin45 30 61 1312.4CD40LG, ELN, TNF
20sb 20358045 6110.4BDKRB1, TNF, PI3
21ascorbic acid45 2610.3PIK3C2A, ELN, CD40LG
22thromboxane a245 2610.3BDKRB1, PIK3C2A
23fenofibrate45 51 1311.3CD40LG, TNF, PIK3C2A
24atorvastatin45 51 30 26 1313.3PIK3C2A, TNF, CD40LG
25ly294002459.3TNF, PIK3C2A, PI3
26hyaluronic acid45 2610.2CD40LG, ELN, AZU1
27histamine45 30 2611.2CD40LG, ELN, TNF, PI3
28dexamethasone45 51 30 1312.1CD40LG, ELN, TNF, PI3
29creatinine459.1PIK3C2A, ELN, CD40LG
30polysaccharide459.1CD40LG, ELN, AZU1
31aspartate459.1CD40LG, ELN, PIK3C2A
32actinomycin d459.0TNF, ELN, CD40LG, BDKRB1
33genistein45 30 61 3 26 1314.0TNF, ELN, CD40LG, BDKRB1
34cyclosporin a45 30 6111.0CD40LG, TNF, PIK3C2A, PI3
35ivig458.9CD40LG, ELN, TNF, PIK3C2A
36fibrinogen458.9PIK3C2A, TNF, ELN, CD40LG
37lactate458.9PIK3C2A, TNF, ELN, CD40LG
38endotoxin458.8CD40LG, MEFV, TNF, AZU1
39cycloheximide458.7TNF, ELN, BDKRB1
40superoxide45 269.6AZU1, PI3, PIK3C2A, TNF
41heparin45 30 26 1311.6CD40LG, ELN, PIK3C2A, AZU1
42arginine458.6CD40LG, ELN, PIK3C2A, AZU1
43glutamate458.5AZU1, PIK3C2A, ELN, CD40LG
44oxygen45 269.5AZU1, PI3, PIK3C2A, TNF
45lipid458.4AZU1, PI3, PIK3C2A, TNF
46retinoic acid45 269.4CD40LG, ELN, TNF, PI3, AZU1
47serine458.3AZU1, PI3, TNF, ELN, CD40LG
48tyrosine458.2AZU1, PI3, PIK3C2A, MEFV, BDKRB1
49vegf458.1AZU1, PIK3C2A, TNF, ELN, CD40LG
50calcium45 51 26 1311.1AZU1, PI3, PIK3C2A, ELN, BDKRB1

GO Terms for genes affiliated with Erysipelas

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Biological processes related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1organ morphogenesisGO:00098879.5ELN, TNF
2regulation of immunoglobulin secretionGO:00510239.5TNF, CD40LG
3response to mechanical stimulusGO:00096129.1BDKRB1, TNF
4protein kinase C-activating G-protein coupled receptor signaling pathwayGO:00072059.0BDKRB1, AZU1
5inflammatory responseGO:00069547.8BDKRB1, CD40LG, MEFV, TNF, AZU1

Molecular functions related to Erysipelas according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:00051649.5CD40LG, TNF

Products for genes affiliated with Erysipelas

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Sources for Erysipelas

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet