MCID: ERY004
MIFTS: 41

Erysipelas malady

Categories: Rare diseases, Infectious diseases, Skin diseases

Aliases & Classifications for Erysipelas

Aliases & Descriptions for Erysipelas:

Name: Erysipelas 12 50 29 52 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11330
ICD10 33 A46
ICD9CM 35 035
MeSH 42 D004886
UMLS 69 C0014733

Summaries for Erysipelas

MalaCards based summary : Erysipelas is related to fasciitis and cellulitis, and has symptoms including exanthema An important gene associated with Erysipelas is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Defensins and C-MYB transcription factor network. The drugs Vancomycin and Penicillin V have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and breast.

Wikipedia : 71 Erysipelas (/ɛrᵻˈsɪpələs/; Greek ἐρυσίπελας, \"red skin\"; also known as \"ignis... more...

Related Diseases for Erysipelas

Diseases related to Erysipelas via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 123)
id Related Disease Score Top Affiliating Genes
1 fasciitis 29.9 ELANE TNF
2 cellulitis 10.3
3 low compliance bladder 10.2 CALCA TNF
4 chromoblastomycosis 10.2 ELANE TNF
5 senile reticular retinal degeneration 10.2 CALCA TNF
6 dancing eyes-dancing feet syndrome 10.2 ELANE ELN
7 benign focal seizures of adolescence 10.2 ELANE ELN
8 optic nerve glioma 10.2 ELANE ELN
9 bardet-biedl syndrome 8 10.2 ELANE ELN
10 radial hypoplasia, triphalangeal thumbs and hypospadias 10.2 ELANE TNF
11 cerebellar disease 10.2 PI3 TNF
12 pulmonary embolism and infarction 10.2 ELANE PI3
13 brucella suis brucellosis 10.2 ELANE PI3
14 central nervous system lymphoma 10.2 CALCA TNF
15 myeloid neoplasms associated with pdgfrb rearrangement 10.2 MEFV TNF
16 tau syndrome 10.2 MEFV TNF
17 infantile hypotonia 10.2 CALCA TNF
18 candidiasis, familial, 4, autosomal recessive 10.2 MEFV TNF
19 mechanical lagophthalmos 10.1 MEFV TNF
20 epidermolysis bullosa dystrophica, ad 10.1 CALCA GUSB
21 atelosteogenesis ii 10.1 ELANE PI3
22 meier-gorlin syndrome 3 10.1 MEFV TNF
23 dermatomycosis 10.1 MEFV TNF
24 benign neonatal seizures 10.1 MEFV TNF
25 malignant histiocytosis 10.1 MEFV TNF
26 gonococcal endophthalmia 10.1 MEFV TNF
27 pyloric stenosis, infantile hypertrophic, 2 10.1 MEFV TNF
28 histiocytoma 10.1 MEFV TNF
29 arthritis 10.1
30 strawberry gallbladder 10.1 MEFV TNF
31 patau syndrome 10.1 MEFV TNF
32 alcoholic hepatitis 10.1 ELANE ELN TNF
33 retinitis pigmentosa 51 10.1 ELANE ELN TNF
34 major depressive disorder and accelerated response to antidepressant drug treatment 10.1 ELANE ELN TNF
35 pancreas lymphoma 10.1 MEFV TNF
36 radial defect robin sequence 10.1 ELANE PI3 TNF
37 uveitis 10.1 LYZ TNF
38 hemangioma of orbit 10.1 ELANE PI3 TNF
39 ulcerative proctitis 10.1 LYZ TNF
40 adnp syndrome 10.1 ELANE PI3 TNF
41 stenosis of lacrimal sac 10.1 ELANE GUSB TNF
42 histiocytosis 10.0 ELANE GUSB TNF
43 renal adenoma 10.0 LYZ TNF
44 infancy electroclinical syndrome 10.0 ELANE TNF
45 bubonic plague 10.0 CALCA LYZ
46 renal oncocytoma 10.0 ELANE ELN
47 acute cor pulmonale 10.0 CALCA ELANE PI3
48 myiasis 10.0 MEFV TNF
49 conjunctival vascular disease 10.0 LYZ TNF
50 malignant testicular leydig cell tumor 10.0 ELANE LYZ

Graphical network of the top 20 diseases related to Erysipelas:



Diseases related to Erysipelas

Symptoms & Phenotypes for Erysipelas

UMLS symptoms related to Erysipelas:


exanthema

Drugs & Therapeutics for Erysipelas

Drugs for Erysipelas (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Vancomycin Approved Phase 4 1404-90-6 441141 14969
2
Penicillin V Approved, Vet_approved Phase 4 87-08-1 6869
3
Daptomycin Approved, Investigational Phase 4,Phase 2 103060-53-3 16129629
4
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613 2171
5 penicillins Phase 4
6 Anti-Bacterial Agents Phase 4,Phase 2
7 Anti-Infective Agents Phase 4,Phase 2
8 Antibiotics, Antitubercular Phase 4
9 Floxacillin Phase 4
10 Antitubercular Agents Phase 4
11
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
12 glucocorticoids Phase 2
13 Hormone Antagonists Phase 2
14 Hormones Phase 2
15 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
16 Anti-Inflammatory Agents Phase 2
17 Antineoplastic Agents, Hormonal Phase 2
18 Torezolid Phase 2
19 Torezolid phosphate Phase 2
20 Dermatologic Agents Phase 2
21
Linezolid Approved, Investigational 165800-03-3 441401
22
Dimenhydrinate Approved 523-87-5 441281
23
Menthol Approved 2216-51-5 16666
24 methicillin

Interventional clinical trials:

(show all 12)
id Name Status NCT ID Phase
1 RCT to Investigate if Prophylactic Antibiotics Prevent Further Episodes of Cellulitis (Erysipelas) of the Leg Completed NCT00552799 Phase 4
2 Study Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in Cellulitis or Erysipelas Completed NCT00295178 Phase 4
3 Duration of ANtibiotic Therapy for CEllulitis Recruiting NCT02032654 Phase 4
4 Short Course of Amoxicillin for Erysipelas Terminated NCT01059123 Phase 4
5 The Use of Oral Steroids in the Treatment of Cellulitis Unknown status NCT00893048 Phase 2
6 A Phase 2 Safety and Exploratory Skin Lesion Measurement of TR-701 FA Study Completed NCT01519778 Phase 2
7 The Effect of the Cosmetic Cream NMBM on Leg Ulcers - a Pilot Study Completed NCT01770509 Phase 1, Phase 2
8 Efficacy and Safety Study of Brilacidin to Treat Serious Skin Infections Completed NCT02052388 Phase 2
9 Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo Recruiting NCT02902822 Phase 2
10 Fat Grafting Used for the Treatment of Breast Cancer Related Lymphedema in China Recruiting NCT02981485 Phase 2
11 Sivextro in Acute Bacterial Skin and Skin Structure Infection (ABSSSI) in Hospitalized Patients. A Global Observational Study Recruiting NCT02991131
12 Effectiveness of Fluoroscopy-guided MLD for Treatment of BCRL Recruiting NCT02609724

Search NIH Clinical Center for Erysipelas

Cochrane evidence based reviews: erysipelas

Genetic Tests for Erysipelas

Genetic tests related to Erysipelas:

id Genetic test Affiliating Genes
1 Erysipelas 29

Anatomical Context for Erysipelas

MalaCards organs/tissues related to Erysipelas:

39
Skin, Testes, Breast, Colon, Neutrophil, B Cells, Pituitary

Publications for Erysipelas

Articles related to Erysipelas:

(show top 50) (show all 529)
id Title Authors Year
1
Pathogenic characterization of Erysipelothrix rhusiopathiae Met-203 type SpaA strains from chronic and subacute swine erysipelas in Japan. ( 27773881 )
2017
2
Low sensitivity of needle aspiration cultures in patients with cellulitis/erysipelas. ( 27652151 )
2016
3
Dermatologic Diseases in 8 of the Cantigas of Holy Mary of Alfonso X the Learned - Part 2: Genital Mutilation, Scrofuloderma, Scabies, Erysipelas, and the Ailments of the King. ( 27156179 )
2016
4
Familial Mediterranean fever patients may have unmet need for treatment of erysipelas-like erythema. ( 27782864 )
2016
5
How to treat a fulminant erysipelas and sepsis caused by Myroides odoratimimus: case report and literature review. ( 27765000 )
2016
6
A Fatal Case of "Bullous Erysipelas-like" Pseudomonas Vasculitis. ( 26955132 )
2016
7
Impetigo, Erysipelas and Cellulitis ( 26866211 )
2016
8
Complicated Skin and Skin Structure Infection After Erysipelas: Urgent Need for Antibiosis and Surgery. ( 26933116 )
2016
9
Pseudo-erysipelas: A new atypical cutaneous manifestation of parvovirus B19 primary infection. ( 26791960 )
2016
10
The effects of amoxicillin, ceftiofur, doxycycline, tiamulin and tulathromycin on swine humoral immune response induced by erysipelas vaccination. ( 27072375 )
2016
11
Meta-analysis of randomised trials comparing a penicillin or cephalosporin with a macrolide or lincosamide in the treatment of cellulitis or erysipelas. ( 27085865 )
2016
12
Complete genome sequence of Erysipelothrix rhusiopathiae strain GXBY-1 isolated from acute swine erysipelas outbreaks in south China. ( 27222802 )
2016
13
High Incidence of Erysipelas After Surgical Treatment for Vulvar Carcinoma: An Observational Study. ( 26807636 )
2016
14
Cellulitis and erysipelas: prevention. ( 26580894 )
2015
15
Risk factors associated with abscess formation among patient with leg erysipelas (cellulitis) in sub-Saharan Africa: a multicenter study. ( 26666633 )
2015
16
Erysipelas, a large retrospective study of aetiology and clinical presentation. ( 26424182 )
2015
17
Safety and efficacy of a new octavalent combined Erysipelas, Parvo and Leptospira vaccine in gilts against Leptospira interrogans serovar Pomona associated disease and foetal death. ( 26100922 )
2015
18
Risk factors associated with a reduced response in the treatment of erysipelas. ( 25706926 )
2015
19
Erysipelas in turkeys, sheep and pigs. ( 25792678 )
2015
20
Endogenous endophthalmitis secondary to erysipelas. ( 26123459 )
2015
21
Diagnosis and management of cellulitis and erysipelas. ( 26255928 )
2015
22
Pseudo-kaposi sarcoma (acroangiodermatitis): occurring after bullous erysipelas. ( 26295854 )
2015
23
Erysipelas Outbreaks in Flocks of Geese in Poland--Biochemical and Genetic Analyses of the Isolates. ( 26478164 )
2015
24
Synergic effect of erysipelas on aggression to the lymphatic system in patients submitted to the excision of a saphenous vein. ( 26344512 )
2015
25
Use of procalcitonin, C-reactive protein and white blood cell count to distinguish between lower limb erysipelas and deep vein thrombosis in the emergency department: A prospective observational study. ( 25982244 )
2015
26
Characterization of <i>Erysipelothrix rhusiopathiae</i> strains isolated from acute swine erysipelas outbreaks in Eastern China. ( 25649849 )
2015
27
An unusual erysipelas-like presentation. ( 24456958 )
2014
28
Microorganisms of the toe web and their importance for erysipelas of the leg. ( 24961650 )
2014
29
Recurrent erysipelas--risk factors and clinical presentation. ( 24884840 )
2014
30
Erysipelas as a superinfection of an oral lymphangioma. ( 24793202 )
2014
31
Pretibial erysipelas-like erythema as the primary manifestation of renal cell carcinoma, a paraneoplastic manifestation. ( 24556357 )
2014
32
Erysipelas and myocarditis. ( 24502912 )
2014
33
Penicillin as a therapeutic option in the treatment of in-hospital erysipelas. ( 24566577 )
2014
34
Erysipelas-like Erythema in a Patient with Familial Mediterranean Fever. ( 25362709 )
2014
35
Erysipelothrix rhusiopathiae contamination in the poultry house environment during erysipelas outbreaks in organic laying hen flocks. ( 24661145 )
2014
36
Unusual presentation of chikungunya virus infection with concomintant erysipelas in a returning traveler from the Caribbean: a case report. ( 25734165 )
2014
37
Prevalence of Met-203 type spaA variant in Erysipelothrix rhusiopathiae isolates and the efficacy of swine erysipelas vaccines in Japan. ( 24405986 )
2014
38
Erysipelas in a free-range layer flock with conjunctival oedema as an unusual clinical sign. ( 24881267 )
2014
39
Complete genome assembly and characterization of an outbreak strain of the causative agent of swine erysipelas--Erysipelothrix rhusiopathiae SY1027. ( 24993343 )
2014
40
Erysipelas in a numbat (Myrmecobius fasciatus). ( 23505731 )
2013
41
Erysipelas-like erythema of familial Mediterranean fever syndrome: a case report with emphasis on histopathologic diagnostic clues. ( 23521609 )
2013
42
Erysipelas-like erythema as the presenting feature of familial Mediterranean fever. ( 22243424 )
2013
43
Risk of deep vein thrombosis in patients with cellulitis and erysipelas: a systematic review and meta-analysis. ( 23948644 )
2013
44
Erysipelas-like erythema as a cutaneous sign of familial Mediterranean fever: a case report and review of the histopathologic findings. ( 23317997 )
2013
45
Erysipelas in laying hens is associated with housing system. ( 23542656 )
2013
46
Genetic susceptibility to non-necrotizing erysipelas/cellulitis. ( 23437094 )
2013
47
Leukocytoclastic vasculitis secondary to erysipelas: an unusual case of noncryoglobulinemic vasculitis in a hepatitis C patient. ( 23872543 )
2013
48
Incidence of deep vein thrombosis in erysipelas or cellulitis of the lower extremities. ( 22913433 )
2013
49
Risk factors for abscess formation in patients with superficial cellulitis (erysipelas) of the leg. ( 23210619 )
2013
50
A case of diffuse large B-cell lymphoma misdiagnosed as an erysipelas of the face. ( 24278087 )
2013

Variations for Erysipelas

Expression for Erysipelas

Search GEO for disease gene expression data for Erysipelas.

Pathways for Erysipelas

GO Terms for Erysipelas

Cellular components related to Erysipelas according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 CALCA ELANE GUSB LYZ TNF
2 specific granule lumen GO:0035580 9.26 ELANE LYZ
3 extracellular region GO:0005576 9.17 CALCA ELANE ELN GUSB LYZ PI3
4 azurophil granule lumen GO:0035578 9.13 ELANE GUSB LYZ

Biological processes related to Erysipelas according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.54 ELANE LYZ TNF
2 inflammatory response GO:0006954 9.46 CALCA LYZ MEFV TNF
3 positive regulation of smooth muscle cell proliferation GO:0048661 9.43 ELANE TNF
4 positive regulation of MAP kinase activity GO:0043406 9.4 ELANE TNF
5 positive regulation of interleukin-8 production GO:0032757 9.32 CALCA TNF
6 negative regulation of growth of symbiont in host GO:0044130 9.26 ELANE TNF
7 positive regulation of interleukin-8 biosynthetic process GO:0045416 8.96 ELANE TNF
8 antimicrobial humoral response GO:0019730 8.8 ELANE LYZ PI3

Sources for Erysipelas

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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