MCID: ERY004
MIFTS: 42

Erysipelas malady

Rare diseases, Infectious diseases categories

Aliases & Classifications for Erysipelas

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Erysipelas, Aliases & Descriptions:

Name: Erysipelas 9 41 11 43 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases


External Ids:

Disease Ontology9 DOID:11330
ICD9CM27 035
MeSH33 D004886
ICD1025 A46

Summaries for Erysipelas

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Wikipedia:63 Erysipelas (/?r??s?p?l?s/; Greek ???????????red skin; also known as \"Ignis sacer\", \"holy fire\", and... more...

MalaCards based summary: Erysipelas is related to familial mediterranean fever, ar and pneumonia. An important gene associated with Erysipelas is PI3 (peptidase inhibitor 3, skin-derived), and among its related pathways are Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways and NF-kappa B signaling pathway. The compounds silicone and glutaraldehyde have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and breast, and related mouse phenotypes are integument and skeleton.

Related Diseases for Erysipelas

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Diseases related to Erysipelas via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 95)
idRelated DiseaseScoreTop Affiliating Genes
1familial mediterranean fever, ar30.3TNF, MEFV
2pneumonia30.0PI3, TNF, PIK3C2A
3vasculitis30.0MEFV, TNF, CD40LG
4skin disease29.8ELN, TNF, PI3
5ischemia29.8PIK3C2A, BDKRB1, AZU1
6hepatitis c29.5CD40LG, TNF
7cellulitis10.7
8arthritis10.5
9calcinosis10.4PIK3C2A
10palindromic rheumatism10.4MEFV
11lymphedema10.4
12polyarteritis nodosa10.3MEFV
13erysipeloid10.3
14breast cancer10.3
15fasciitis10.3
16schnitzler syndrome10.3CD40LG
17hemorrhagic fever10.3CD40LG
18scrub typhus10.2CD40LG
19necrotizing fasciitis10.2
20scarlet fever10.2
21acute respiratory distress syndrome10.2PI3, TNF
22periodic fever, familial10.2MEFV, TNF
23lupus erythematosus10.2
24discoid lupus erythematosus10.2
25blau syndrome10.2MEFV, TNF
26respiratory failure10.1TNF, PIK3C2A
27bacteremia10.1
28mycosis fungoides10.1
29cholera10.1
30lymphangitis10.1
31tinea pedis10.1
32dermatitis10.1
33elephantiasis10.1
34influenza10.1
35myocarditis10.1
36sarcoma10.1
37hennekam syndrome10.1
38st anthony's fire10.1
39tumor necrosis factor receptor 1 associated periodic syndrome10.1
40leptospirosis10.1CD40LG, PIK3C2A
41behcet's disease10.1TNF, MEFV
42dengue disease10.0CD40LG, PIK3C2A
43peritonitis10.0TNF, AZU1, MEFV
44pulmonary disease, chronic obstructive10.0ELN, TNF, PI3
45cork-handlers' disease10.0ELN, PI3, TNF
46spondyloarthropathy 110.0TNF, CD40LG
47vascular disease9.9ELN, PIK3C2A, TNF
48microcephaly with or without chorioretinopathy, lymphedema, or mental retardation9.9
49poikiloderma, hereditary fibrosing, with tendon contractures, myopathy, and pulmonary fibrosis9.9
50cholestasis-lymphedema syndrome9.9

Graphical network of the top 20 diseases related to Erysipelas:



Diseases related to erysipelas

Symptoms for Erysipelas

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Drugs & Therapeutics for Erysipelas

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Drug clinical trials:

Search ClinicalTrials for Erysipelas

Search NIH Clinical Center for Erysipelas

Genetic Tests for Erysipelas

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Anatomical Context for Erysipelas

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MalaCards organs/tissues related to Erysipelas:

31
Skin, Testes, Breast, Colon, Eye, Bone, Lymph node, Spleen, Retina, Heart, Thyroid, Monocytes, B cells, Pituitary, Neutrophil

Animal Models for Erysipelas or affiliated genes

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MGI Mouse Phenotypes related to Erysipelas:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.6BDKRB1, CD40LG, MEFV, TNF
2MP:00053908.4TNF, ELN, MEFV, CD40LG
3MP:00053877.9BDKRB1, MEFV, TNF, CD40LG, PIK3C2A
4MP:00053767.6MEFV, TNF, ELN, CD40LG, BDKRB1, PIK3C2A
5MP:00107687.6MEFV, TNF, BDKRB1, PIK3C2A, CD40LG, ELN

Publications for Erysipelas

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Articles related to Erysipelas:

(show top 50)    (show all 503)
idTitleAuthorsYear
1
Erysipelothrix rhusiopathiae contamination in the poultry house environment during erysipelas outbreaks in organic laying hen flocks. (24661145)
2014
2
Erysipelas-like Erythema in a Patient with Familial Mediterranean Fever. (25362709)
2014
3
Prevalence of Met-203 type spaA variant in Erysipelothrix rhusiopathiae isolates and the efficacy of swine erysipelas vaccines in Japan. (24405986)
2014
4
Erysipelas in a free-range layer flock with conjunctival oedema as an unusual clinical sign. (24881267)
2014
5
Risk of deep vein thrombosis in patients with cellulitis and erysipelas: a systematic review and meta-analysis. (23948644)
2013
6
The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of firmicutes and the organism's intracellular adaptations. (21478354)
2011
7
Characterization of Erysipelothrix species isolates from clinically affected pigs, environmental samples, and vaccine strains from six recent swine erysipelas outbreaks in the United States. (20719987)
2010
8
Erysipelas: a common potentially dangerous infection. (17994173)
2007
9
Risk factors for erysipelas of the leg in Tunisia: a multicenter case-control study. (16484815)
2006
10
A blistering disease: bullous erysipelas. (16880441)
2006
11
Oedema as a risk factor for multiple episodes of cellulitis/erysipelas of the lower leg: a series with community follow-up. (17034523)
2006
12
Bullous erysipelas: clinical presentation, staphylococcal involvement and methicillin resistance. (16319471)
2006
13
Erysipelas after breast cancer treatment (26 cases). (16409908)
2005
14
Wound healing of chronic leg ulcers under the influence of erysipelas. (14965798)
2004
15
Cellulitis and erysipelas. (15865787)
2004
16
Oral pristinamycin versus standard penicillin regimen to treat erysipelas in adults: randomised, non-inferiority, open trial. (12386036)
2002
17
Lymphoscintigraphic evaluation in patients after erysipelas. (11191659)
2000
18
Erysipelas and tinea pedis. (10948816)
2000
19
Erysipelas in malleefowl. (10451726)
1999
20
Erysipelas: clinical and bacteriologic spectrum and serological aspects. (8922808)
1996
21
St. Anthony's fire: an eponym for ergotism, not erysipelas. (7604780)
1995
22
Pre-septal cellulitis and facial erysipelas due to Moraxella species. (7955474)
1994
23
Streptococcal arthritis and erysipelas complicating dental extraction. (8422570)
1993
24
Facial erysipelas: report of a case and review of the literature. (1890524)
1991
25
Erysipelas. (2228369)
1990
26
Erysipelas complicating chronic discoid lupus erythematosus of the face--a case report and review of erysipelas. (2680180)
1989
27
Study of granulocyte function of peripheral blood in recurrent erysipelas. (2612708)
1989
28
Lucigenin-amplified chemiluminescence in blood and synovial fluid phagocytes of pigs with erysipelas arthritis. (4096165)
1985
29
Prophylactic antibiotics in recurrent erysipelas. (2857399)
1985
30
Serotypes of Erysipelothrix rhusiopathiae strains isolated from slaughter pigs affected with chronic erysipelas. (6748441)
1984
31
Septic prepatellar bursitis due to erysipelas. (7306248)
1981
32
In defense of erysipelas vaccine. (7364625)
1980
33
Granulomatous lesions in pigs associated with the use of an oil-based erysipelas vaccine. (614024)
1977
34
The histochemistry of prefascial lymph vessels in recurrent erysipelas. (4148228)
1973
35
Leukocyte migration test in recurrent erysipelas. (4120805)
1973
36
Triple sugar iron agar as an aid in the diagnosis of erysipelas. (13598680)
1958
37
Modified Swine Erysipelas Vaccine. (17649050)
1958
38
The incidence of arthritis in swine following vaccination for swine erysipelas. (13498229)
1958
39
Experimental evaluation of culture and serum vaccination for the control of swine erysipelas. V. Vaccination of weanling pigs using a change in the dosage relationship of culture and serum. (13201496)
1954
40
Studies of Swine Erysipelas. II. Cultural Characteristics and Virulence of Strains of Erysipelothrix Rhusiopathiae Isolated in Canada. (17648553)
1952
41
Erysipelas in turkeys; a case report. (18124860)
1949
42
DIFFERENTIAL diagnosis of swine erysipelas. (20988172)
1946
43
SPECIES SPECIFIC IMMUNITY TO HEMOLYTIC STREPTOCOCCUS INFECTIONS INDUCED IN WHITE MICE BY IMMUNIZATION WITH AN R VARIANT OF AN ERYSIPELAS STRAIN : The Significance of Cell Autolysis in Relation to Antibody Response. (16560103)
1938
44
Erysipelas. (18744161)
1937
45
The Statistics of Erysipelas in England and Wales. (20475199)
1933
46
Relationship of the Streptococci Causing Erysipelas. (18012891)
1929
47
Syphilitic Meningo-Myelitis: Erysipelas: Recovery. (20759725)
1901
48
Seasonable Influences in Erysipelas, with Statistics. (21409070)
1895
49
A Case of Erysipelas Neonatorum Treated by Antistreptococcic Serum. (20755865)
1895
50
Vitiligo as a Sequela of Influenza and Erysipelas. (20753304)
1891

Variations for Erysipelas

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Expression for genes affiliated with Erysipelas

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Search GEO for disease gene expression data for Erysipelas.

Pathways for genes affiliated with Erysipelas

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Pathways related to Erysipelas according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6MEFV, TNF
29.5CD40LG, TNF
3
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
9.5CD40LG, TNF
4
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway58
9.5CD40LG, TNF
59.5CD40LG, TNF
6
Show member pathways
9.3PIK3C2A, TNF

Compounds for genes affiliated with Erysipelas

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Compounds related to Erysipelas according to GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1silicone4310.0ELN, CD40LG
2glutaraldehyde439.9ELN, CD40LG
3hydroxychloroquine43 1210.9TNF, CD40LG
4blys439.9TNF, CD40LG
5il-12439.9CD40LG, TNF
6lactose43 1210.8CD40LG, ELN
7sulfasalazine28 43 49 1212.8CD40LG, TNF
8doxycycline43 1210.8ELN, CD40LG
9mycophenolate mofetil43 49 1211.8CD40LG, TNF
10hirudin439.7PIK3C2A, CD40LG
11erythromycin43 2 49 1212.6CD40LG, PIK3C2A
12neopterin439.6TNF, CD40LG
13okt3439.5TNF, ELN, CD40LG
14theophylline43 28 24 1212.5CD40LG, ELN
15melphalan43 49 1211.5TNF, PIK3C2A
16rituximab43 49 1211.5CD40LG, TNF
17dermatan sulfate439.5ELN, AZU1
18n acetylcysteine439.5CD40LG, ELN, TNF
19indomethacin43 28 59 1212.4CD40LG, ELN, TNF
20sb 20358043 5910.4BDKRB1, TNF, PI3
21ascorbic acid43 2410.3PIK3C2A, ELN, CD40LG
22thromboxane a243 2410.3BDKRB1, PIK3C2A
23fenofibrate43 49 1211.3CD40LG, TNF, PIK3C2A
24atorvastatin43 49 28 24 1213.3PIK3C2A, TNF, CD40LG
25ly294002439.3TNF, PIK3C2A, PI3
26hyaluronic acid43 2410.2CD40LG, ELN, AZU1
27histamine43 28 2411.2CD40LG, ELN, TNF, PI3
28dexamethasone43 49 28 1212.1CD40LG, ELN, TNF, PI3
29creatinine439.1PIK3C2A, ELN, CD40LG
30polysaccharide439.1CD40LG, ELN, AZU1
31aspartate439.1CD40LG, ELN, PIK3C2A
32actinomycin d439.0TNF, ELN, CD40LG, BDKRB1
33genistein43 28 59 2 24 1214.0TNF, ELN, CD40LG, BDKRB1
34cyclosporin a43 28 5911.0CD40LG, TNF, PIK3C2A, PI3
35ivig438.9CD40LG, ELN, TNF, PIK3C2A
36fibrinogen438.9PIK3C2A, TNF, ELN, CD40LG
37lactate438.9PIK3C2A, TNF, ELN, CD40LG
38endotoxin438.8CD40LG, MEFV, TNF, AZU1
39cycloheximide438.7TNF, ELN, BDKRB1
40superoxide43 249.6AZU1, PI3, PIK3C2A, TNF
41heparin43 28 24 1211.6CD40LG, ELN, PIK3C2A, AZU1
42arginine438.6CD40LG, ELN, PIK3C2A, AZU1
43glutamate438.5AZU1, PIK3C2A, ELN, CD40LG
44oxygen43 249.5AZU1, PI3, PIK3C2A, TNF
45lipid438.4AZU1, PI3, PIK3C2A, TNF
46retinoic acid43 249.4CD40LG, ELN, TNF, PI3, AZU1
47serine438.3AZU1, PI3, TNF, ELN, CD40LG
48tyrosine438.2AZU1, PI3, PIK3C2A, MEFV, BDKRB1
49vegf438.1AZU1, PIK3C2A, TNF, ELN, CD40LG
50calcium43 49 24 1211.1AZU1, PI3, PIK3C2A, ELN, BDKRB1

GO Terms for genes affiliated with Erysipelas

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Biological processes related to Erysipelas according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1organ morphogenesisGO:00098879.5ELN, TNF
2regulation of immunoglobulin secretionGO:00510239.5TNF, CD40LG
3response to mechanical stimulusGO:00096129.1BDKRB1, TNF
4protein kinase C-activating G-protein coupled receptor signaling pathwayGO:00072059.0BDKRB1, AZU1
5inflammatory responseGO:00069547.8BDKRB1, CD40LG, MEFV, TNF, AZU1

Molecular functions related to Erysipelas according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:00051649.5CD40LG, TNF

Products for genes affiliated with Erysipelas

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Sources for Erysipelas

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet