MCID: ESC003
MIFTS: 59

Escobar Syndrome malady

Categories: Genetic diseases, Rare diseases, Eye diseases, Fetal diseases

Aliases & Classifications for Escobar Syndrome

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Aliases & Descriptions for Escobar Syndrome:

Name: Escobar Syndrome 49 11 45 22 23 51 67
Multiple Pterygium Syndrome 10 45 22 23 67
Pterygium 10 12 36 65
Pterygium Syndrome 45 23 67
Evmps 45 51 67
Autosomal Recessive Non-Lethal Multiple Pterygium Syndrome 45 51
Autosomal Recessive Multiple Pterygium Syndrome 45 51
Multiple Pterygium Syndrome, Escobar Variant 67 24
Escobar Variant Multiple Pterygium Syndrome 45 51
 
Pterygium Colli Syndrome 45 67
Pterygium Universale 45 67
Multiple Pterygium Syndrome, Non-Lethal Type 67
Nonlethal Type Multiple Pterygium Syndrome 67
Multiple Pterygium Syndrome Nonlethal Type 45
Multiple Pterygium Syndrome Escobar Type 45
Familial Pterygium Syndrome 23
Surfer's Eye 10

Characteristics:

Orphanet epidemiological data:

51
escobar syndrome:
Inheritance: Autosomal recessive; Age of onset: Infancy,Neonatal

HPO:

61
escobar syndrome:
Inheritance: autosomal recessive inheritance


Classifications:



External Ids:

OMIM49 265000
Disease Ontology10 DOID:0002116, DOID:0080110
ICD9CM29 372.4, 372.40
MeSH36 D011625
Orphanet51 2990
ICD10 via Orphanet28 Q79.8
MedGen34 CN031762
UMLS65 C0033999

Summaries for Escobar Syndrome

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UniProtKB/Swiss-Prot:67 Multiple pterygium syndrome, Escobar variant: Non-lethal form of arthrogryposis multiplex congenita. It is an autosomal recessive condition characterized by excessive webbing (pterygia), congenital contractures (arthrogryposis), and scoliosis. Variable other features include intrauterine death, congenital respiratory distress, short stature, faciocranial dysmorphism, ptosis, low-set ears, arachnodactyly and cryptorchism in males. Congenital contractures are common and may be caused by reduced fetal movements at sensitive times of development. Possible causes of decreased fetal mobility include space constraints such as oligohydramnion, drugs, metabolic conditions or neuromuscular disorders including myasthenia gravis.

MalaCards based summary: Escobar Syndrome, also known as multiple pterygium syndrome, is related to popliteal pterygium syndrome 1 and multiple pterygium syndrome, lethal type, and has symptoms including amniotic constriction ring, symphalangism affecting the phalanges of the hand and finger syndactyly. An important gene associated with Escobar Syndrome is CHRNG (Cholinergic Receptor Nicotinic Gamma Subunit), and among its related pathways are Succinylcholine Pathway, Pharmacokinetics/Pharmacodynamics and Postsynaptic nicotinic acetylcholine receptors. Affiliated tissues include skin, eye and lung, and related mouse phenotype respiratory system.

Disease Ontology:10 A genetic disease that is characterized by permanently bent fingers (camptodactyly), short stature, rocker-bottom or club feet, joints that are bent in a fixed position (contractures), union or webbing of the skin between the fingers (syndactyly), and/or webbing of the neck, inside bend of the elbows, back of the knees and armpits.

NIH Rare Diseases:45 Multiple pterygium syndrome, escobar type is characterized by webbing of the neck, elbows, and/or knees, and joint contractures. symptoms of escobar syndrome are present from birth. it can be caused by mutations in the chrng gene. it tends to be inherited in an autosomal recessive fashion. last updated: 1/29/2010

Genetics Home Reference:23 Multiple pterygium syndrome is a condition that is evident before birth with webbing of the skin (pterygium) at the joints and a lack of muscle movement (akinesia) before birth. Akinesia frequently results in muscle weakness and joint deformities called contractures that restrict the movement of joints (arthrogryposis). As a result, multiple pterygium syndrome can lead to further problems with movement such as arms and legs that cannot fully extend.

OMIM:49 Multiple pterygium syndromes comprise a group of multiple congenital anomaly disorders characterized by webbing... (265000) more...

Wikipedia:68 Multiple pterygium syndrome is a cutaneous condition inherited in an autosomal dominant fashion. more...

Related Diseases for Escobar Syndrome

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Diseases in the Escobar Syndrome family:

Escobar Syndrome, Type B

Diseases related to Escobar Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 62)
idRelated DiseaseScoreTop Affiliating Genes
1popliteal pterygium syndrome 133.2IRF6, SATB2
2multiple pterygium syndrome, lethal type32.0CHRNA1, CHRND, CHRNG, RAPSN
3van der woude syndrome30.7IRF6, SATB2
4popliteal pterygium syndrome 2, lethal type12.2
5antecubital pterygium12.2
6pterygium of the conjunctiva and cornea12.0
7double pterygium12.0
8escobar syndrome, type b11.9
9central pterygium11.8
10progressive peripheral pterygium11.8
11multiple pterygium syndrome x-linked11.8
12pterygium colli mental retardation digital anomalies11.8
13autosomal dominant popliteal pterygium syndrome11.8
14pterygium colli-intellectual disability-digital anomalies syndrome11.8
15spondylohypoplasia, arthrogryposis and popliteal pterygium11.8
16chrna1-related multiple pterygium syndrome, lethal type11.8
17chrnd-related multiple pterygium syndrome, lethal type11.8
18multiple pterygium syndrome, dominant11.8
19pterygium of the conjunctiva, familial form11.8
20x-linked lethal multiple pterygium syndrome11.8
21arthrogryposis, distal, type 811.1
22blepharophimosis, epicanthus inversus, and ptosis, type 110.8
23noonan syndrome 110.8
24bart-pumphrey syndrome10.8
25fetal akinesia deformation sequence10.4
26pinguecula10.4
27endotheliitis10.3
28scleritis10.3
29interstitial lung disease10.2CHRND, CHRNG
30myasthenic syndrome, congenital, 1a, slow-channel10.2CHRNA1, CHRND
31myasthenic syndrome, congenital, 1b, fast-channel10.2CHRNA1, CHRND
32slti salem syndrome10.2CHRNA1, CHRND
33astigmatism10.1
34irf6-related disorders10.1
35cataract10.1
36conjunctivochalasis10.0
37specific bursitis often of occupational origin10.0CHRNA1, CHRND, CHRNG
38keratitis9.9
39burns9.9
40leprosy9.9
41nail-patella syndrome9.9
42cleft lip9.9
43scoliosis9.8
44esophageal atresia9.8
45esophagitis9.8
46nemaline myopathy9.8
47myopathy9.8
48lung disease9.8
49malignant hyperthermia9.8
50lip disease9.8IRF6, SATB2

Graphical network of the top 20 diseases related to Escobar Syndrome:



Diseases related to escobar syndrome

Symptoms for Escobar Syndrome

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Symptoms by clinical synopsis from OMIM:

265000

Clinical features from OMIM:

265000

Symptoms:

 51 (show all 64)
  • webbed neck/pterygium colli
  • sternal/sternum anomalies
  • pectus excavatum
  • scoliosis
  • cutaneous/amniotic bands/webbing of joints
  • syndactyly of fingers/interdigital palm
  • symphalangy of fingers
  • restricted joint mobility/joint stiffness/ankylosis
  • autosomal recessive inheritance
  • microcephaly
  • long face
  • facial structural asymmetry/facial hemiatrophy/facial hemihypertrophy
  • hypertelorism
  • downslanted palpebral fissures/anti-mongoloid slanting palpebral fissures
  • micrognathia/retrognathia/micrognathism/retrognathism
  • pointed chin
  • anomalies of eyelids, eyelashes and lacrimal system
  • ptosis
  • epicanthic folds
  • telecanthus/canthal dystopy
  • cleft lip and palate
  • high vaulted/narrow palate
  • low set ears/posteriorly rotated ears
  • hearing loss/hypoacusia/deafness
  • anomalies of spine, vertebrae and pelvis
  • vertebral segmentation anomaly/hemivertebrae
  • absent/hypotonic/flaccid abdominal wall muscles
  • umbilical hernia
  • arthrogryposis
  • popliteal web
  • camptodactyly of fingers
  • foot anomalies
  • skin hypoplasia/aplasia/atrophy
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • late puberty/hypogonadism/hypogenitalism
  • movement disorder
  • short stature/dwarfism/nanism
  • intrauterine growth retardation
  • dolichocephaly/scaphocephaly
  • pterygion
  • strabismus/squint
  • long philtrum
  • anomalies of tongue, gingiva and oral mucosa
  • cleft palate without cleft lip/submucosal cleft palate/bifid uvula
  • anomalies of ear and hearing
  • conductive deafness/hearing loss
  • anomalies of the ribs
  • spina bifida occulta
  • inguinal/inguinoscrotal/crural hernia
  • capillary hemangioma/nevus/naevus flammeus/port-wine stain
  • low hair line (back)
  • structural anomalies of the digestive tract
  • hypoplastic lungs/pulmonary hypoplasia/agenesis
  • aortic valve anomaly/incompetence/insufficiency/regurgitation/bicuspid
  • congenital cardiac anomaly/malformation/cardiopathy
  • aortic dilatation/dilation
  • clitoris/labia majora/labia minora/female external genitalia hypoplasia
  • micropenis/small penis/agenesis
  • undescended/ectopic testes/cryptorchidia/unfixed testes
  • hypoplastic scrotum/hemiscrotum/scrotal ridges
  • abnormal gait
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • muscle hypotrophy/atrophy/dystrophy/agenesis/amyotrophy
  • failure to thrive/difficulties for feeding in infancy/growth delay

HPO human phenotypes related to Escobar Syndrome:

(show all 98)
id Description Frequency HPO Source Accession
1 amniotic constriction ring hallmark (90%) HP:0009775
2 symphalangism affecting the phalanges of the hand hallmark (90%) HP:0009773
3 finger syndactyly hallmark (90%) HP:0006101
4 scoliosis hallmark (90%) HP:0002650
5 limitation of joint mobility hallmark (90%) HP:0001376
6 pectus excavatum hallmark (90%) HP:0000767
7 webbed neck hallmark (90%) HP:0000465
8 camptodactyly of finger typical (50%) HP:0100490
9 aplasia/hypoplasia of the abdominal wall musculature typical (50%) HP:0010318
10 popliteal pterygium typical (50%) HP:0009756
11 aplasia/hypoplasia of the skin typical (50%) HP:0008065
12 short stature typical (50%) HP:0004322
13 vertebral segmentation defect typical (50%) HP:0003422
14 arthrogryposis multiplex congenita typical (50%) HP:0002804
15 respiratory insufficiency typical (50%) HP:0002093
16 abnormality of the foot typical (50%) HP:0001760
17 umbilical hernia typical (50%) HP:0001537
18 intrauterine growth retardation typical (50%) HP:0001511
19 ptosis typical (50%) HP:0000508
20 telecanthus typical (50%) HP:0000506
21 downslanted palpebral fissures typical (50%) HP:0000494
22 low-set, posteriorly rotated ears typical (50%) HP:0000368
23 micrognathia typical (50%) HP:0000347
24 facial asymmetry typical (50%) HP:0000324
25 hypertelorism typical (50%) HP:0000316
26 pointed chin typical (50%) HP:0000307
27 epicanthus typical (50%) HP:0000286
28 long face typical (50%) HP:0000276
29 microcephaly typical (50%) HP:0000252
30 cognitive impairment occasional (7.5%) HP:0100543
31 hypoplasia of penis occasional (7.5%) HP:0008736
32 aplasia/hypoplasia of the lungs occasional (7.5%) HP:0006703
33 spina bifida occulta occasional (7.5%) HP:0003298
34 skeletal muscle atrophy occasional (7.5%) HP:0003202
35 low posterior hairline occasional (7.5%) HP:0002162
36 abnormality of the abdominal organs occasional (7.5%) HP:0002012
37 aortic dilatation occasional (7.5%) HP:0001724
38 abnormality of the aortic valve occasional (7.5%) HP:0001646
39 gait disturbance occasional (7.5%) HP:0001288
40 abnormality of the ribs occasional (7.5%) HP:0000772
41 strabismus occasional (7.5%) HP:0000486
42 conductive hearing impairment occasional (7.5%) HP:0000405
43 long philtrum occasional (7.5%) HP:0000343
44 dolichocephaly occasional (7.5%) HP:0000268
45 cleft palate occasional (7.5%) HP:0000175
46 abnormality of female external genitalia occasional (7.5%) HP:0000055
47 scrotal hypoplasia occasional (7.5%) HP:0000046
48 cryptorchidism occasional (7.5%) HP:0000028
49 anterior clefting of vertebral bodies HP:0009761
50 antecubital pterygium HP:0009760
51 neck pterygia HP:0009759
52 intercrural pterygium HP:0009757
53 popliteal pterygium HP:0009756
54 diaphragmatic eventration HP:0009110
55 absence of labia majora HP:0008729
56 dysplastic patella HP:0006446
57 patellar aplasia HP:0006443
58 bilateral camptodactyly HP:0005617
59 exostosis of the external auditory canal HP:0004459
60 short stature HP:0004322
61 dislocated radial head HP:0003083
62 fused cervical vertebrae HP:0002949
63 hip dislocation HP:0002827
64 kyphosis HP:0002808
65 arthrogryposis multiplex congenita HP:0002804
66 downturned corners of mouth HP:0002714
67 scoliosis HP:0002650
68 neonatal respiratory distress HP:0002643
69 hypoplastic nipples HP:0002557
70 pulmonary hypoplasia HP:0002089
71 talipes calcaneovalgus HP:0001884
72 rocker bottom foot HP:0001838
73 camptodactyly of toe HP:0001836
74 talipes equinovarus HP:0001762
75 decreased fetal movement HP:0001558
76 umbilical hernia HP:0001537
77 arachnodactyly HP:0001166
78 syndactyly HP:0001159
79 axillary pterygia HP:0001060
80 rib fusion HP:0000902
81 long clavicles HP:0000890
82 congenital diaphragmatic hernia HP:0000776
83 ptosis HP:0000508
84 downslanted palpebral fissures HP:0000494
85 abnormality of the neck HP:0000464
86 conductive hearing impairment HP:0000405
87 low-set ears HP:0000369
88 micrognathia HP:0000347
89 long philtrum HP:0000343
90 hypertelorism HP:0000316
91 epicanthus HP:0000286
92 long face HP:0000276
93 high palate HP:0000218
94 cleft palate HP:0000175
95 narrow mouth HP:0000160
96 hypospadias HP:0000047
97 cryptorchidism HP:0000028
98 inguinal hernia HP:0000023

UMLS symptoms related to Escobar Syndrome:


conjunctival opacity, conjunctival bleb, mass of eye structure, joint swelling, arthralgia

Drugs & Therapeutics for Escobar Syndrome

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Drugs for Escobar Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 122)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Dexamethasoneapproved, investigationalPhase 4190950-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Baycadron
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
Dexameth
Dexamethansone
 
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone acetate
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone sodium phosphate
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamethsone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
Ozurdex
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
2
Ethinyl EstradiolapprovedPhase 465957-63-65991
Synonyms:
17 alpha-Ethinylestradiol
17 alpha-Ethynylestradiol
17 alpha-Ethynyloestradiol
17 alpha-ethinyestradiol
17-Ethinyl-3,17-estradiol
17-Ethinyl-3,17-oestradiol
17-Ethinylestradiol
17-Ethynylestradiol
17-Ethynylestradiol ram
17-Ethynyloestradiol
17-alpha-Ethinyl-17-beta-estradiol
17-alpha-Ethynyl-17-beta-oestradiol
17-alpha-Ethynylestradiol
17-alpha-Ethynylestradiol-17-beta
17-alpha-ethynyl estradiol
17-ethinyl-3,17-estradiol
17-ethinyl-3,17-oestradiol
17-ethinylestradiol
17.alpha.-Ethinyl-17.beta.-estradiol
17.alpha.-Ethinylestradiol
17.alpha.-Ethynyl-17.beta.-oestradiol
17.alpha.-Ethynylestradiol
17.alpha.-Ethynylestradiol-l7.beta.
17.alpha.-Ethynyloestradiol
17.alpha.-Ethynyloestradiol-17.beta.
17a-Ethinyl-17b-estradiol
17a-Ethinylestradiol
17a-Ethynyl-17b-oestradiol
17a-Ethynylestradiol
17a-Ethynylestradiol-l7b
17a-Ethynyloestradiol
17a-Ethynyloestradiol-17b
17alpha-Ethinyl estradiol
17alpha-Ethinylestradiol
17alpha-Ethinylestradiol-17beta
17alpha-Ethynylestradiol
17alpha-Ethynyloestradiol
17alpha-Ethynyloestradiol-17beta
17α-ethynylestradiol
406932-93-2
46263_FLUKA
46263_RIEDEL
57-63-6
77538-56-8
AC-2169
AC1L1LK6
AI3-52941
Aethinyloestradiolum
Aethinyoestradiol
Aethinyoestradiol [German]
Alora
Amenoron
Amenorone
Anovlar
BIDD:ER0162
BRN 2419975
Bio-0610
C07534
CCRIS 286
CHEBI:4903
CHEMBL691
CID5991
CPD000058319
Certostat
Chee-O-Gen
Chee-O-Genf
Cyclosa
D004997
D00554
DB00977
Dicromil
Diognat-E
Diogyn E
Diogyn-E
Diprol
Dyloform
E4876_SIGMA
EE
EE(sub 2)
EE2
EINECS 200-342-2
EO
ETHINYLESTRADIOL
Effik Brand of Ethinyl Estradiol
Ertonyl
Esclim
Esteed
Estigyn
Estinyl
Estinyl (TN)
Eston-E
Estopherol
Estoral
Estoral (Orion)
Estoral (VAN)
Estoral [Orion]
Estoral {[Orion]}
Estorals
Estradiol, Ethinyl
Estradiol, Ethynyl
Estring
Estrogen
Ethidol
Ethinoral
Ethinyl E2
Ethinyl Estradiol Hemihydrate
Ethinyl Estradiol [USP]
 
Ethinyl Estradiol, (8 alpha)-Isomer
Ethinyl Oestradiol Effik
Ethinyl estradiol
Ethinyl estradiol (USP)
Ethinyl-Oestradiol Effik
Ethinyl-Oestranol
Ethinyl-oestranol
Ethinylestradiol
Ethinylestradiol (JP15/INN)
Ethinylestradiol Jenapharm
Ethinylestradiol [INN:BAN:JAN]
Ethinylestradiolum
Ethinylestradiolum [INN-Latin]
Ethinylestriol
Ethinyloestradiol
Ethinyloestradiol [Steroidal oestrogens]
Ethy 11
Ethynyl estradiol
Ethynylestradiol
Ethynylestradiol, Ethinyl Estradiol
Ethynyloestradiol
Eticyclin
Eticyclol
Eticylol
Etinestrol
Etinestryl
Etinilestradiol
Etinilestradiol [INN-Spanish]
Etinilestradiolo
Etinilestradiolo [DCIT]
Etinoestryl
Etistradiol
Etivex
Evra
Feminone
Fempatch
Follicoral
Ginestrene
Gynodiol
Gynolett
HMS2051I19
HSDB 3587
Halodrin
Hemihydrate, Ethinyl Estradiol
Inestra
Innofem
Jenapharm Brand of Ethinyl Estradiol
Jenapharm, Ethinylestradiol
Kolpolyn
LMST02010036
LS-231
Linoral
Lynoral
MLS000028479
MLS000758274
Marvelon
Menolyn
Menostar
Mercilon
Microfollin
Microfollin Forte
MolPort-001-794-636
NCGC00091533-01
NCGC00091533-04
NCGC00091533-05
NCI60_000234
NSC-10973
NSC10973
Neo-Estrone
Nogest-S
Novestrol
OVULEN-21
OVULEN-28
Oradiol
Orestralyn
Orestrayln
Organon Brand of Ethinyl Estradiol
Ortho-Cyclen
Ovex
Oviol
PUBERTAL ETHINYL ESTRADIOL STUDY
Palonyl
Perovex
Primogyn
Primogyn C
Primogyn M
Progynon C
Progynon M
Prosexol
S1625_Selleck
SAM001247008
SGCUT00127
SMR000058319
Schering Brand of Ethinyl Estradiol
Spanestrin
Thiuram E
Thiuranide
UNII-423D2T571U
Vagifem
Varnoline
WLN: L E5 B666TTT&J E1 FQ F1UU1 OQ
Ylestrol
component of Demulen
component of Oracon
component of Ortrel
ethinyl estradiol
ethynyl estradiol
to_000048
3
MetforminapprovedPhase 41645657-24-9, 1115-70-414219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMBG
DMGG
Diabefagos
Diabetosan
Diabex
Diaformin
Dianben
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Meguan
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin Hydrochloride
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
Obimet
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
4
Cyproterone Acetateapproved, investigationalPhase 439427-51-0
Synonyms:
Androcur
 
Cyproterone
Cyproterone 17-O-acetate
5
Tobramycinapproved, investigationalPhase 411132986-56-45496, 36294
Synonyms:
1-Epitobramycin
11098-01-4
11111-45-8
3'-Deoxykanamycin B
3'-Deoxykanamycin b
32986-56-4
34337-51-4
37321-13-4
49842-07-1 (Sulfate)
54330-95-9
70322-33-7
79645-27-5
A 12253A
AB00513858
AC1L1KGY
AC1L1VI0
AC1O7GFJ
AC1Q2AOW
AKOS000715235
Aktob
BAS 00463364
BIDD:GT0503
BPBio1_000647
BRN 1357507
BSPBio_000587
BSPBio_002036
Bethkis
Brulamycin
C00397
C18H37N5O9
CAS-32986-56-4
CHEBI:28864
CHEBI:533587
CHEMBL1747
CID11340303
CID36294
CID5496
CID6604388
CID9804613
CID9934285
CPD000058793
D00063
DB00684
Deoxykanamycin B
Distobram
EINECS 251-322-5
Gotabiotic
HMS1569N09
HMS2090B16
HMS2092M17
HSDB 3259
KBio2_001552
KBio2_004120
KBio2_006688
KBio3_001536
KBioGR_001104
KBioSS_001552
Kitabis Pak
LS-146940
LS-187329
Lilly 47663
MLS000069544
MolPort-001-934-131
MolPort-003-665-548
MolPort-003-939-629
NCGC00016814-01
NCGC00178852-01
NCGC00178852-02
NEBRAMYCIN
NF 6
NSC 180514
 
NSC180514
Nebcin
Nebcin (Sulfate)
Nebicin
Nebramycin 6
Nebramycin VI
Nebramycin factir 6
Nebramycin factor 6
Nebramycin-Faktor 6
O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine
Obracin
Obramycin
Prestwick0_000544
Prestwick1_000544
Prestwick2_000544
Prestwick3_000544
Prestwick_850
S2514_Selleck
SAM001246911
SMR000058793
SPBio_000295
SPBio_002508
SPECTRUM1500579
SPRC-AB01
STK182610
Spectrum2_000078
Spectrum3_000588
Spectrum4_000752
Spectrum5_001038
Spectrum_001072
Sybryx
T4014_SIGMA
TOA-(1-6)2TB-(4-1)TOC
TOA-(1-6)TOB-(4-1)TOC
TOBRAMYCIN SULFATE
TOY
Tenebrimycin
Tenemycin
Tobacin
Tobi
Tobi Podhaler
Tobracin
Tobracin (TN)
Tobracin (tn)
Tobradex
Tobradistin
Tobralex
Tobramaxin
Tobramicin
Tobramicina
Tobramicina [INN-Spanish]
Tobramitsetin
Tobramycetin
Tobramycin
Tobramycin (JP15/USP)
Tobramycin Sulfate
Tobramycin [USAN:BAN:INN:JAN]
Tobramycin for Inhalation
Tobramycin solution for inhalation
Tobramycin, Free Base
Tobramycine
Tobramycine [INN-French]
Tobramycinum
Tobramycinum [INN-Latin]
Tobrased
Tobrasone
Tobrex
Tobrex (TN)
Tobrex (tn)
UNII-VZ8RRZ51VK
tobramycin
tobramycin solution for inhalation
6
Bevacizumabapproved, investigationalPhase 4, Phase 2, Phase 3, Phase 11875216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
7
Miconazoleapproved, investigationalPhase 4, Phase 2302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
8
Estradiolapproved, investigationalPhase 4109450-28-25757, 53477783
Synonyms:
(+)-3,17b-Estradiol
(17b)-Estra-1,3,5(10)-triene-3,17-diol
(17beta)-Estra-1,3,5(10)-triene-3,17-diol
.alpha.-Estradiol
.alpha.-Oestradiol
.beta.-Estradiol
.beta.-Oestradiol
1,3,5[10]-Estratriene-3,17beta-diol 3-sulfate
1,3,5[10]-Estratriene-3,17beta-diol 3-sulphate
13b-Methyl-1,3,5(10)-gonatriene-3,17b-ol
17 beta-Estradiol
17-.BETA.-Estradiol
17-E
17-beta
17-beta-OH-estradiol
17-beta-estradiol
17.beta.-Estradiol
17.beta.-Oestradiol
17E
17b-Estradiol
17b-Oestradiol
17beta Oestradiol
17beta oestradiol
17beta-Estra-1,3,5(10)-triene-3,17-diol
17beta-Estradiol
17beta-Oestradiol
1jgl
1qkt
1qku
2d06
3,17-Epidihydroxyestratriene
3,17-beta-Estradiol
3,17-beta-Oestradiol
3,17.beta.-Estradiol
3,17b-Dihydroxyestra-1,3,5(10)-triene
3,17b-Estradiol
3,17beta-Estradiol
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulfate
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulphate
50-28-2
73459-61-7
873662-39-6
AC-10460
AC1L1L2K
Aerodiol
Agofollin
Alora
Altrad
Amnestrogen
Aquadiol
B-Estradiol
BEDOs
BIDD:ER0125
BIDD:PXR0065
BPBio1_000532
BSPBio_000482
BSPBio_001065
Bardiol
Benzhormovarine
Beta-estradiol
Bio-0812
Bio-E-Gel
Bio1_000403
Bio1_000892
Bio1_001381
Bio2_000363
Bio2_000843
C00951
C18H24O2
CCRIS 280
CHEBI:16469
CHEMBL135
CID5757
CMC_11154
CPD-352
CPD000059126
Climaderm
Climara
Climara (TN)
Climara Forte
Compudose
Compudose 200
Compudose 365
Corpagen
D-3,17beta-Estradiol
D-Estradiol
D-Oestradiol
D00105
DB00783
Depo-estradiol
Dermestril
Destradiol
Dihydro-Theelin
Dihydrofollicular hormone
Dihydrofolliculin
Dihydromenformon
Dihydrotheelin
Dihydroxyesterin
Dihydroxyestrin
Dihydroxyoestrin
Dimenformon
Diogyn
Diogynets
Divigel
Divigel (TN)
E 2
E 8875
E(sub 2)
E0025
E1024_SIGMA
E1132_SIGMA
E2257_SIGMA
E2758_SIGMA
E8875_SIGMA
EINECS 200-023-8
EU-0100503
Elestrin
Encore
Epiestriol 50
Esclim
Estra-1,3,5(10)-triene-3,17b-diol
Estrace
Estrace (TN)
Estraderm
Estraderm (TN)
Estraderm MX
Estraderm TTS
Estraderm TTS 100
Estraderm TTS 50
Estradiol
Estradiol Transdermal System
Estradiol Valerate
Estradiol [USAN:INN]
Estradiol acetate
Estradiol benzoate
Estradiol cypionate
Estradiol valerate
Estradiol-17 beta
Estradiol-17-beta
Estradiol-17.beta.
Estradiol-17beta
Estradiol-3,17beta
Estradiolo
Estradiolo [DCIT]
Estradiolum
Estradiolum [INN]
Estradot
Estraldine
Estrapak 50
Estrasorb
Estrasorb (TN)
Estreva
Estrifam
Estring
Estring (TN)
Estring Vaginal Ring
Estring vaginal ring
Estroclim
Estroclim 50
Estrodiolum
Estrofem 2
 
Estrofem Forte
Estrogel
Estrogel (TN)
Estrogel HBF
Estrovite
Evamist
Evorel
Extrasorb
Femanest
Femestral
Femestrol
Femogen
Fempatch
Femring
Femtrace
Femtran
Follicyclin
Gelestra
Ginedisc
Ginosedol
GynPolar
Gynergon
Gynestrel
Gynodiol
Gynoestryl
HMS1362E07
HMS1569I04
HMS1792E07
HMS1990E07
HMS2051C17
HMS2090E18
HSDB 3589
IDI1_002118
Innofem
Innofem (TN)
KBio2_000405
KBio2_002269
KBio2_002973
KBio2_004837
KBio2_005541
KBio2_007405
KBio3_000769
KBio3_000770
KBio3_002749
KBioGR_000405
KBioGR_002269
KBioSS_000405
KBioSS_002270
LMST02010001
LS-137
Lamdiol
Lio-Oid
Lopac0_000503
MLS000069494
MLS000758312
MLS001076331
Macrodiol
Macrol
Menest
Menorest
Menostar
Microdiol
Minivelle
MolPort-001-794-632
NCGC00091544-00
NCGC00091544-01
NCGC00091544-02
NCGC00091544-04
NCGC00091544-05
NCGC00091544-06
NCGC00091544-07
NCGC00091544-08
NCGC00091544-09
NCGC00091544-12
NCGC00179321-01
NCGC00179321-02
NSC-9895
NSC9895
Nordicol
Oesclim
Oestergon
Oestra-1,3,5(10)-triene-3,17b-diol
Oestradiol
Oestradiol Berco
Oestradiol R
Oestradiol-17-beta
Oestradiol-17.beta.
Oestradiol-17beta
Oestradiolum
Oestrogel
Oestroglandol
Oestrogynal
Ovahormon
Ovasterol
Ovastevol
Ovociclina
Ovocyclin
Ovocycline
Ovocylin
Perlatanol
Polyestradiol
Prestwick0_000441
Prestwick1_000441
Prestwick2_000441
Prestwick3_000441
Prestwick_207
Primofol
Profoliol
Profoliol B
Progynon
Progynon DH
Progynon-DH
S-21400
S1709_Selleck
SAM001247032
SK-Estrogens
SL-1100
SMP1_000121
SMR000059126
SPBio_002421
Sandrena 1
Sandrena Gel
Sisare Gel
Spectrum5_002055
Syndiol
Systen
Tradelia
Trial SAT
Trocosone
UNII-4TI98Z838E
VIVELLE-DOT
Vagifem
Vagifem (TN)
Vivelle
Vivelle (TN)
Vivelle Dot
Vivelle-dot
Zerella
Zesteem
Zesteen
Zumenon
[2,4,6,7-3H]-E2
[3H]-estradiol
[3H]]estradiol
b-Estradiol
beta-Estradiol
beta-Estradiol 3-sulfate
beta-Estradiol 3-sulphate
bmse000642
cMAP_000005
cis-Estradiol
cis-Oestradiol
component of Menrium
delta-Estradiol
delta-Oestradiol
estradiol
estradiol-17beta
nchembio.168-comp3
nchembio.76-comp2
nchembio775-comp2
nchembio794-comp6
nchembio860-comp1
progynon
9
FluorouracilapprovedPhase 4168451-21-83385
Synonyms:
1-fluoro-1h-pyrimidine-2,4-dione
1004-03-1
1upf
2,4-Dihydroxy-5-fluoropyrimidine
2,4-Dioxo-5-fluoropryimidine
2,4-Dioxo-5-fluoropyrimidine
47576_FLUKA
4921-97-5
5 FU Lederle
5 FU medac
5 Fluorouracil
5 Fluorouracil biosyn
5 HU Hexal
5-FU
5-FU (TN)
5-FU Lederle
5-FU medac
5-Faracil
5-Fluor-2,4(1H,3H)-pyrimidindion
5-Fluor-2,4(1H,3H)-pyrimidindion [Czech]
5-Fluor-2,4-dihydroxypyrimidin
5-Fluor-2,4-dihydroxypyrimidin [Czech]
5-Fluor-2,4-pyrimidindiol
5-Fluor-2,4-pyrimidindiol [Czech]
5-Fluoracil
5-Fluoracil [German]
5-Fluoracyl
5-Fluoro-2,4(1H,3H)-pyrimidinedione
5-Fluoro-2,4-pyrimidinedione
5-Fluoropyrimidin-2,4-diol
5-Fluoropyrimidine-2,4-dione
5-Fluorouracil
5-Fluorouracil-biosyn
5-Fluoruracil
5-Fluoruracil [German]
5-Fluracil
5-Ftouracyl
5-HU Hexal
5-fluoro uracil
5-fluoro-1H-pyrimidine-2,4-dione
5-fluoropyrimidine-2,4(1H,3H)-dione
5-fluorouracil
51-21-8
5FU
79108-01-3
AC-11201
AC1L1FTE
AC1Q4N2X
AI3-25297
AKOS000119162
AKOS003237897
AccuSite
Actino-Hermal
Adrucil
Adrucil (TN)
Allergan Brand of Fluorouracil
Arumel
BB_NC-0576
BSPBio_002048
C07649
C4H3FN2O2
CCRIS 2582
CHEBI:46345
CHEMBL185
CID3385
CPD0-1327
CPD000038082
CSP Brand of Fluorouracil
Carac
Carac (TN)
Carzonal
Cinco FU
Cytosafe
D005472
D00584
DB00544
Dakota Brand of Fluorouracil
Dakota, Fluorouracile
Dermatech Brand of Fluorouracil
Dermik Brand of Fluorouracil
DivK1c_000054
EINECS 200-085-6
EU-0100536
Effluderm
Effluderm (free base)
Efudex
Efudix
Efurix
F 6627
F0151
F6627_SIGMA
F8423_SIGMA
FT-0082524
FU
Ferrer Brand of Fluorouracil
Fiverocil
Fluoro Uracil
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoro-uracile
Fluoro-uracilo
Fluoroblastin
Fluoroplex
Fluoroplex (TN)
Fluorouracil
Fluorouracil (JP15/USP/INN)
Fluorouracil GRY
Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt
Fluorouracil Teva Brand
Fluorouracil [USAN:INN:BAN:JAN]
 
Fluorouracil-GRY
Fluorouracile
Fluorouracile Dakota
Fluorouracile [DCIT]
Fluorouracilo
Fluorouracilo Ferrer Far
Fluorouracilo [INN-Spanish]
Fluorouracilum
Fluorouracilum [INN-Latin]
Fluoruracil
Fluouracil
Flurablastin
Fluracedyl
Fluracil
Fluracilum
Fluri
Fluril
Fluro Uracil
Fluroblastin
Flurodex
Flurouracil
Flurox
Ftoruracil
Gry Brand of Fluorouracil
HMS1920O18
HMS2090I04
HMS2091F19
HMS500C16
HSDB 3228
Haemato Brand of Fluorouracil
Haemato fu
Haemato-fu
Hexal Brand of Fluorouracil
I07-0022
ICN Brand of Fluorouracil
IDI1_000054
IN1335
KBio1_000054
KBio2_001321
KBio2_003889
KBio2_006457
KBio3_001268
KBioGR_001253
KBioSS_001321
Kecimeton
LS-153
Lopac-F-6627
Lopac0_000536
MLS000069498
MLS002415705
MolPort-000-156-102
MolPort-003-990-447
MolPort-004-758-143
MolPort-004-758-144
MolPort-005-861-486
NCGC00015442-01
NCGC00015442-03
NCGC00015442-10
NCGC00091349-01
NCGC00091349-02
NCGC00091349-03
NCGC00091349-04
NCGC00091349-05
NCGC00091349-07
NCGC00091349-08
NCI60_001652
NINDS_000054
NSC 19893
NSC-19893
NSC19893
Neocorp Brand of Fluorouracil
Neofluor
Onkofluor
Onkoworks Brand of Fluorouracil
Phthoruracil
Phtoruracil
Queroplex
Ribofluor
Riemser Brand of Fluorouracil
Ro 2-9757
Ro-2-9757
Roche Brand of Fluorouracil
S1209_Selleck
SAM002264615
SMR000038082
SPBio_000291
SPECTRUM1500305
STK297802
Spectrum2_000076
Spectrum3_000434
Spectrum4_000557
Spectrum5_000718
Spectrum_000841
T5233394
TL8006093
Teva Brand of Fluorouracil
Timazin
U 8953
U-8953
UNII-U3P01618RT
UPCMLD-DP130
UPCMLD-DP130:001
URF
Ulup
WLN: T6MVMVJ EF
ZINC00897110
biosyn Brand of Fluorouracil
fluorouracil
inhibits thymilidate synthetase
medac Brand of Fluorouracil
nchembio.90-comp3
nchembio809-comp6
ribosepharm Brand of Fluorouracil
tetratogen
10
CyproteronePhase 4392098-66-05284537
Synonyms:
(1R,3aS,3bR,7aR,8aS,8bS,8cS,10aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one
2098-66-0
6-Chlor-delta(6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron
6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron
6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron [German]
6-chloro-17-hydroxy-1beta,2beta-dihydro-3'H-cyclopropa[1,2]pregna-4,6-diene-3,20-dione
AC-6213
AC1L1EZB
AC1L27WO
Apo-cyproterone
BAY 94-8367
BAY94-8367
BSPBio_003462
C22H27ClO3
CHEBI:50742
CHEMBL142130
CID10044976
CID16417
CID3015
CID5284537
CID5702275
Ciproterona
Ciproterona Servycal
Ciproterona Servycal (TN)
Ciproterona [INN-Spanish]
Ciproterone
Ciproterone [DCIT]
CyPat
Cyproteron
Cyproterone (INN)
Cyproterone [INN:BAN]
 
Cyproterone acetate
Cyproteronum
Cyproteronum [INN-Latin]
D07766
DB04839
DivK1c_000786
Gen-Cyproterone
HMS1922K16
HMS502H08
IDI1_000786
KBio1_000786
KBio2_002052
KBio2_004620
KBio2_007188
KBio3_002966
KBioGR_001485
KBioSS_002052
LS-58798
MolPort-003-981-177
MolPort-005-932-862
NCGC00178048-01
NINDS_000786
Novo-cyproterone
SH 80881
SPBio_001594
SPECTRUM1503921
Spectrum2_001597
Spectrum3_001901
Spectrum4_000853
Spectrum5_001362
Spectrum_001572
UNII-E61Q31EK2F
cyproterone
11Contraceptive AgentsPhase 41706
12TetrahydrozolinePhase 4, Phase 3542
13Androgen AntagonistsPhase 4252
14AndrogensPhase 41162
15Contraceptive Agents, MalePhase 4202
16Contraceptives, OralPhase 43734
17EstrogensPhase 42144
18Anti-Bacterial AgentsPhase 4, Phase 2, Phase 19140
19Antibiotics, AntitubercularPhase 4, Phase 2, Phase 15971
20MitomycinsPhase 4, Phase 2219
21Nucleic Acid Synthesis InhibitorsPhase 4, Phase 23836
22Alkylating AgentsPhase 4, Phase 23582
23Polyestradiol phosphatePhase 41095
24Estradiol 3-benzoatePhase 41094
25Estradiol valeratePhase 41094979-32-8
26Protease InhibitorsPhase 44558
27Hypoglycemic AgentsPhase 44503
28Estradiol 17 beta-cypionatePhase 41094
29Peripheral Nervous System AgentsPhase 4, Phase 318510
30Immunologic FactorsPhase 4, Phase 2, Phase 3, Phase 118483
31Dermatologic AgentsPhase 4, Phase 24555
32Immunosuppressive AgentsPhase 4, Phase 210422
33Anti-Allergic AgentsPhase 4, Phase 31312
34Angiogenesis InhibitorsPhase 4, Phase 2, Phase 3, Phase 13688
35CyclosporinsPhase 4, Phase 2873
36Calcineurin InhibitorsPhase 4, Phase 21223
37Angiogenesis Modulating AgentsPhase 4, Phase 2, Phase 3, Phase 13611
38Antifungal AgentsPhase 4, Phase 23015
39Anti-Infective AgentsPhase 4, Phase 2, Phase 117220
40Antirheumatic AgentsPhase 4, Phase 3, Phase 28496
41Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 1, Phase 28478
42AntiemeticsPhase 43213
43HormonesPhase 4, Phase 1, Phase 211748
44Antineoplastic Agents, HormonalPhase 44256
45Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 1, Phase 29988
46
Loteprednol EtabonatePhase 44482034-46-6444025
Synonyms:
82034-46-6
AC1L9FKJ
AKOS005145741
Alrex
Alrex, Lotemax, Loteprednol etabonate
CDDD-5604
CHEBI:31784
CHEMBL1200865
CID444025
CPD000469178
D01689
DB00873
HGP-1
HMS2051F16
IDR-90102
IDR-90103
 
Locort
Loteflam
Lotemax
Lotemax (TN)
Loteprednol etabonate
Loteprednol etabonate (JAN/USAN)
Loterox
MLS001424221
MolPort-003-848-424
NCGC00164594-01
P-5604
S1669_Selleck
SAM001246630
SMR000469178
ZINC03920673
chloromethyl (8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
chloromethyl 17alpha-[(ethoxycarbonyl)oxy]-11beta-hydroxy-3-oxoandrosta-1,4-diene-17beta-carboxylate
47Ophthalmic SolutionsPhase 4, Phase 31006
48HIV Protease InhibitorsPhase 44558
49Hormone AntagonistsPhase 4, Phase 1, Phase 210002
50glucocorticoidsPhase 4, Phase 1, Phase 23896

Interventional clinical trials:

(show top 50)    (show all 66)
idNameStatusNCT IDPhase
1Role of Sub-Conjunctival Bevacizumab in Post Pterygium Excision ManagementCompletedNCT01736449Phase 4
2Efficacy of Topical Cyclosporine 0.05% in the Prevention of Ocular Surface Inflammation Secondary to PterygiaCompletedNCT00383396Phase 4
3Intraocular Pressure With Loteprednol and DexamethasoneCompletedNCT00781300Phase 4
4Effects of Metformin vs Oral Contraceptives on CV Risk Markers in PCOSCompletedNCT00428311Phase 4
5Pterygium Head Body MMC1: Two Different Surgical Procedures and Their Effect on Endothelial Cell Count.Not yet recruitingNCT02641132Phase 4
6Strategies for Management of Recurrent PterygiumNot yet recruitingNCT02530801Phase 4
7Intralesional Ranibizumab on Pterygium Vascularity, Size and Recurrence Rate: a Pilot StudyCompletedNCT02342392Phase 2, Phase 3
8To Compare Fibrin Glue and Suture in Primary Pterygium Excision With Amniotic Membrane TransplantationCompletedNCT00457223Phase 2, Phase 3
9Subconjunctival Bevacizumab and Recurrent PterygiumCompletedNCT01744756Phase 2, Phase 3
10Topical Bevacizumab for Preventing Recurrent PterygiumCompletedNCT01311960Phase 3
11Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in China Beijing HospitalCompletedNCT00320762Phase 3
12Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in Beijing Remin HospitalCompletedNCT00321035Phase 3
13Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in China Zhong-Shan HospitalCompletedNCT00320957Phase 3
14Evaluation of Tranilast to Treat Pterygium Before ExcisionCompletedNCT01003613Phase 3
15Pterygium Treatment Using Single Beta-therapy as Adjuvant Treatment Compared to Conjunctival AutograftCompletedNCT01024257Phase 3
16Autologous ex Vivo Conjunctival Epithelial Cell Expansion for Ocular Surface TransplantationCompletedNCT00346450Phase 3
17Comparison of Glue With Sutures for Pterygium SurgeryRecruitingNCT00326560Phase 3
18Intralesional Bevacizumab Injection on Primary PterygiumRecruitingNCT01380678Phase 3
19Ologen(Oculusgen)-Glaucoma and Pterygium Historical Control Study in China Shanghai Sixth People's HospitalRecruitingNCT00478790Phase 3
20Mindfulness-based Eating in Patients With Irritable Bowel SyndromeRecruitingNCT02681666Phase 3
21Efficacy of Thoracic Paravertebral Block in the Reduction of Acute Post-surgical Pain in Patients With Breast CancerRecruitingNCT02609321Phase 3
22Comparison Amongst Scleral, Corneal and Amniotic Membrane Grafts to Restore Scleral ThinningEnrolling by invitationNCT00801073Phase 2, Phase 3
23The Use of Natural Latex Biomembrane in Ocular Surface ReconstructionCompletedNCT01250353Phase 2
24Safety Study of Avastin Used as Adjunctive Therapy in Pterygium SurgeryCompletedNCT01115517Phase 2
25The Effect of Bevacizumab (Avastin) on PterygiumCompletedNCT00592176Phase 2
26Safety and Efficacy of Cyclosporine Ophthalmic Emulsion in Patients With Primary PterygiumCompletedNCT01109056Phase 2
27Corneal Epithelium Repair and Therapy Using Autologous Limbal Stem Cell TransplantationRecruitingNCT02148016Phase 1, Phase 2
28Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF InjectionRecruitingNCT02486484Phase 2
29Cultivated Stem Cell Transplantation for the Treatment of Limbal Stem Cell DeficiencyActive, not recruitingNCT00845117Phase 1, Phase 2
30Assessment of the Efficacy of Ocular Dipyridamole in the Treatment of Dry Eye Symptomology in Subjects With PterygiumNot yet recruitingNCT02782260Phase 2
31Bevacizumab for Primary Pterygium TreatmentCompletedNCT01686529Phase 1
32Bevacizumab Injection for Recurrent PterygiumCompletedNCT02007174Phase 1
33Assessment of Fibrin Glue in Pterygium Surgery and Other Forms of External Eye SurgeryCompletedNCT00344201Phase 1
34Ranibizumab for the Inhibition of Neovascularization in PterygiaCompletedNCT00768963Phase 1
35Efficacy and Safety of Sub-tenon Ranibizumab for Recurrent PterygiaCompletedNCT01169909Phase 1
36Amniotic Membrane Associated With Conjunctival Autograft Versus Conjunctival Autograft for Recurrent PterygiaEnrolling by invitationNCT00802620Phase 1
37The Application of Fibrin Glue in Ocular Surface DiseasesWithdrawnNCT00155402Phase 1
38Conjunctival Autologous Transplantation Using Fibrin Glue in Primary PterygiaCompletedNCT00949728
39Determinants of Pterygium Occurrence and Recurrence in a Rural African PopulationCompletedNCT00713180
40Clinical Analysis of Recurrence Patterns Following Conjunctival Autografts for Pterygium SurgeryCompletedNCT02059837
41Comparison Between Sutureless and Glue Free Versus Sutured Limbal Conjunctival Autograft in Primary Pterygium SurgeryCompletedNCT02009072
42Different Surgical Techniques for Pterygium SurgeryCompletedNCT02002338
43Recurrent Pterygium Surgery Using Mitomycin C With Limbal Conjunctival or Amniotic MembraneCompletedNCT01319721
44Rotational Narrow Strip Versus Full Conjunctival Graft in Pterygium ExcisionCompletedNCT01083927
45Polyglactin Sutures Versus Nylon Sutures for Suturing of Conjunctival Autograft in Pterygium Surgery: a Randomised Controlled TrialCompletedNCT00391573
46Randomized Controlled Trial of Subconjunctival Bevacizumab Injection in Impending Recurrent PterygiumCompletedNCT01288404
47ICG Angiography in Amniotic Membrane Graft and Conjunctival Autograft After Pterygium ExcisionCompletedNCT00383825
48The Application of Fibrin Glue (Tissucol Duo Quick) in External Eye SurgeriesCompletedNCT02138019
49Different Hemostasis According to the Anesthetic AgentsCompletedNCT02151305
50Comparison of Subconjuctival Versus Topical Bevacizumab as Adjunct Therapy to TrabeculectomyCompletedNCT01425112

Search NIH Clinical Center for Escobar Syndrome


Cochrane evidence based reviews: pterygium

Genetic Tests for Escobar Syndrome

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Genetic tests related to Escobar Syndrome:

id Genetic test Affiliating Genes
1 Escobar Syndrome22
2 Multiple Pterygium Syndrome22

Anatomical Context for Escobar Syndrome

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MalaCards organs/tissues related to Escobar Syndrome:

33
Skin, Eye, Lung, Testes, Prostate, Endothelial, Tongue

Animal Models for Escobar Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Escobar Syndrome:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.5CHRNG, RAPSN, SATB2, TBX22

Publications for Escobar Syndrome

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Articles related to Escobar Syndrome:

(show all 20)
idTitleAuthorsYear
1
Chronic abdominal pain in a patient with escobar syndrome. (25196531)
2015
2
Orthopaedic manifestations and treatment outcome of two siblings with Escobar syndrome and homozygous mutations in the CHRNG gene. (25411939)
2015
3
Escobar syndrome with heterotaxia and esophageal atresia: case report. (25365855)
2014
4
Nonlethal multiple pterygium syndrome: Escobar syndrome. (24472885)
2014
5
Is webbing (pterygia) a constant feature in patients with Escobar syndrome? (24254455)
2013
6
Airway management in Escobar syndrome: A formidable challenge. (24403623)
2013
7
Neuromotor synapses in Escobar syndrome. (24038971)
2013
8
Clinical phenotype and the lack of mutations in the CHRNG, CHRND, and CHRNA1 genes in two Indian families with Escobar syndrome. (23448903)
2013
9
Anesthetic approach to a patient with multiple pterygium (Escobar) syndrome. (22486906)
2012
10
Escobar syndrome mimicing congenital patellar syndrome. (25610221)
2012
11
Anesthesic management for escobar syndrome: case report. (21541234)
2011
12
Escobar syndrome in three male patients of same family. (21814339)
2011
13
Escobar syndrome: is this child prone to malignant hyperthermia? (19076525)
2009
14
Absence of beta-tropomyosin is a new cause of Escobar syndrome associated with nemaline myopathy. (19155175)
2009
15
Lumbar epidural anesthesia for the child with Escobar syndrome. (16719892)
2006
16
Escobar syndrome is a prenatal myasthenia caused by disruption of the acetylcholine receptor fetal gamma subunit. (16826520)
2006
17
Escobar syndrome (multiple pterygium syndrome) associated with thoracic kyphoscoliosis, lordoscoliosis, and severe restrictive lung disease: a case report. (18751807)
2005
18
Escobar syndrome. (15330967)
2004
19
Extensor-tendon hypoplasia and multiple pterygia: Escobar syndrome in a 7-year-old boy. (12479430)
2002
20
Scoliosis in Escobar syndrome (multiple pterygium syndrome). Description of two cases. (9009416)
1996

Variations for Escobar Syndrome

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UniProtKB/Swiss-Prot genetic disease variations for Escobar Syndrome:

67
id Symbol AA change Variation ID SNP ID
1CHRNGp.Val107GlyVAR_030753
2CHRNGp.Arg239CysVAR_030755

Clinvar genetic disease variations for Escobar Syndrome:

5
id Gene Variation Type Significance SNP ID Assembly Location
1CHRNGNM_005199.4(CHRNG): c.13C> T (p.Gln5Ter)single nucleotide variantPathogenicrs267606725GRCh37Chr 2, 233404470: 233404470
2CHRNGNM_005199.4(CHRNG): c.715C> T (p.Arg239Cys)single nucleotide variantPathogenicrs121912670GRCh37Chr 2, 233407702: 233407702
3CHRNGNM_005199.4(CHRNG): c.301_309dupAGGGTGCCGduplicationPathogenicrs863223313GRCh37Chr 2, 233405372: 233405380
4CHRNGNM_005199.4(CHRNG): c.1408C> T (p.Arg470Ter)single nucleotide variantPathogenicrs121912671GRCh37Chr 2, 233410280: 233410280
5CHRNGNM_005199.4(CHRNG): c.320T> G (p.Val107Gly)single nucleotide variantPathogenicrs267606726GRCh37Chr 2, 233405391: 233405391
6CHRNGNM_005199.4(CHRNG): c.136C> T (p.Arg46Ter)single nucleotide variantPathogenicrs121912672GRCh37Chr 2, 233404782: 233404782
7CHRNGNM_005199.4(CHRNG): c.753_754delCTdeletionPathogenicrs767503038GRCh37Chr 2, 233407740: 233407741
8CHRNGNM_005199.4(CHRNG): c.117dupC (p.Asn40Glnfs)duplicationPathogenicrs797044677GRCh37Chr 2, 233404763: 233404763
9CHRNGNM_005199.4(CHRNG): c.428C> G (p.Pro143Arg)single nucleotide variantPathogenicrs765746795GRCh37Chr 2, 233406161: 233406161
10CHRNGCHRNG, 1-BP DUP, 459AduplicationPathogenic

Expression for genes affiliated with Escobar Syndrome

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Search GEO for disease gene expression data for Escobar Syndrome.

Pathways for genes affiliated with Escobar Syndrome

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GO Terms for genes affiliated with Escobar Syndrome

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Biological processes related to Escobar Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1neuromuscular synaptic transmissionGO:000727410.0CHRNA1, CHRND
2cation transportGO:00068129.9CHRNA1, CHRND
3ion transportGO:00068119.4CHRNA1, CHRND, CHRNG
4cation transmembrane transportGO:00986559.3CHRNA1, CHRND, CHRNG
5synaptic transmission, cholinergicGO:00072719.3CHRNA1, CHRND, CHRNG

Molecular functions related to Escobar Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular ligand-gated ion channel activityGO:00052309.3CHRNA1, CHRND, CHRNG
2acetylcholine receptor activityGO:00154649.2CHRNA1, CHRND, CHRNG

Sources for Escobar Syndrome

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet