MCID: ESP006
MIFTS: 20

Esophageal Adenosquamous Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Esophageal Adenosquamous Carcinoma

MalaCards integrated aliases for Esophageal Adenosquamous Carcinoma:

Name: Esophageal Adenosquamous Carcinoma 12 14 69

Classifications:



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Disease Ontology 12 DOID:5625
NCIt 46 C27421
UMLS 69 C2063886

Summaries for Esophageal Adenosquamous Carcinoma

Disease Ontology : 12 An esophageal carcinoma that derives from squamous cells and gland-like cells.

MalaCards based summary : Esophageal Adenosquamous Carcinoma is related to squamous cell carcinoma and mucoepidermoid esophageal carcinoma. An important gene associated with Esophageal Adenosquamous Carcinoma is WWOX (WW Domain Containing Oxidoreductase), and among its related pathways/superpathways are G12-G13 in Cellular Signaling and Adhesion. Related phenotype is no phenotypic analysis.

Related Diseases for Esophageal Adenosquamous Carcinoma

Diseases related to Esophageal Adenosquamous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 29.1 CDH1 CEACAM5 WWOX
2 mucoepidermoid esophageal carcinoma 10.2 CEACAM5 WWOX
3 malignant spiradenoma 10.1 CEACAM5 KRT5
4 bile duct mucoepidermoid carcinoma 10.1 CEACAM5 KRT5
5 prostate squamous cell carcinoma 10.1 CEACAM5 KRT5
6 breast adenomyoepithelioma 10.1 CEACAM5 KRT5
7 breast myoepithelial neoplasm 10.1 CEACAM5 KRT5
8 esophagitis 10.1
9 adenosquamous carcinoma 10.1
10 malignant biphasic mesothelioma 10.1 CEACAM5 KRT5
11 cervical clear cell adenocarcinoma 10.1 CEACAM5 KRT5
12 alveolar periostitis 10.1 JUN WWOX
13 cloacogenic carcinoma 10.1 CEACAM5 KRT5
14 meibomian cyst 10.0 CEACAM5 JUN
15 esophagus squamous cell carcinoma 9.9 CDH1 WWOX
16 gastric cardia carcinoma 9.9 CDH1 WWOX
17 breast cystic hypersecretory carcinoma 9.9 CDH1 KRT5
18 gastric signet ring cell adenocarcinoma 9.9 CDH1 CEACAM5
19 microinvasive gastric cancer 9.9 CDH1 CEACAM5
20 chondroid chordoma 9.9 CDH1 CEACAM5
21 lymphoepithelioma-like carcinoma 9.9 CDH1 KRT5
22 infiltrative basal cell carcinoma 9.9 CDH1 CEACAM5
23 lipid-rich carcinoma 9.9 CDH1 KRT5
24 papillary adenocarcinoma 9.8 CDH1 CEACAM5
25 pre-malignant neoplasm 9.8 CDH1 KRT5
26 bile duct adenocarcinoma 9.8 CDH1 CEACAM5
27 gastrointestinal system benign neoplasm 9.8 CDH1 CEACAM5
28 intestinal benign neoplasm 9.8 CDH1 CEACAM5
29 spindle cell carcinoma 9.8 CDH1 KRT5
30 in situ carcinoma 9.8 CDH1 KRT5
31 malignant ovarian surface epithelial-stromal neoplasm 9.8 CDH1 CEACAM5
32 ovary epithelial cancer 9.8 CDH1 CEACAM5
33 ductal carcinoma in situ 9.8 CDH1 KRT5
34 pancreas adenocarcinoma 9.8 CDH1 CEACAM5
35 colorectal adenocarcinoma 9.7 CDH1 CEACAM5
36 ovarian cancer 1 9.7 CDH1 CEACAM5
37 female reproductive organ cancer 9.7 CDH1 CEACAM5
38 mesothelioma, malignant 9.7 CDH1 CEACAM5
39 endocrine gland cancer 9.7 CDH1 CEACAM5
40 colon adenocarcinoma 9.6 CDH1 CEACAM5
41 gallbladder cancer 9.6 CDH1 CEACAM5
42 gastrointestinal system cancer 9.6 CDH1 CEACAM5 WWOX
43 breast squamous cell carcinoma 9.5 CDH1 CEACAM5 KRT5
44 breast metaplastic carcinoma 9.5 CDH1 CEACAM5 KRT5
45 malignant epithelial mesothelioma 9.5 CDH1 CEACAM5 KRT5
46 lung cancer susceptibility 3 9.4 CDH1 CEACAM5 JUN
47 cholangiocarcinoma 9.4 CDH1 CEACAM5
48 cell type cancer 9.2 CDH1 CEACAM5 KRT5 WWOX
49 esophageal cancer 9.1 CDH1 CEACAM5 JUN WWOX
50 gastric cancer 9.0 CDH1 CEACAM5 JUN

Graphical network of the top 20 diseases related to Esophageal Adenosquamous Carcinoma:



Diseases related to Esophageal Adenosquamous Carcinoma

Symptoms & Phenotypes for Esophageal Adenosquamous Carcinoma

MGI Mouse Phenotypes related to Esophageal Adenosquamous Carcinoma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 8.92 CDH1 JUN KRT5 WWOX

Drugs & Therapeutics for Esophageal Adenosquamous Carcinoma

Search Clinical Trials , NIH Clinical Center for Esophageal Adenosquamous Carcinoma

Genetic Tests for Esophageal Adenosquamous Carcinoma

Anatomical Context for Esophageal Adenosquamous Carcinoma

Publications for Esophageal Adenosquamous Carcinoma

Articles related to Esophageal Adenosquamous Carcinoma:

# Title Authors Year
1
Esophageal adenosquamous carcinoma mimicking acantholytic squamous cell carcinoma. ( 29085501 )
2017
2
Primary esophageal adenosquamous carcinoma: a retrospective analysis of 24 cases. ( 24127755 )
2013
3
Esophageal adenosquamous carcinoma in a cat. ( 11217072 )
2001

Variations for Esophageal Adenosquamous Carcinoma

Expression for Esophageal Adenosquamous Carcinoma

Search GEO for disease gene expression data for Esophageal Adenosquamous Carcinoma.

Pathways for Esophageal Adenosquamous Carcinoma

Pathways related to Esophageal Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.41 CDH1 JUN
2 11.34 CDH1 CEACAM5
3 11.07 JUN KRT5
4 10.85 CDH1 JUN
5 10.3 CDH1 JUN

GO Terms for Esophageal Adenosquamous Carcinoma

Biological processes related to Esophageal Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to organic substance GO:0010033 8.62 CDH1 JUN

Sources for Esophageal Adenosquamous Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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