MCID: ESP020
MIFTS: 50

Esophageal Atresia malady

Categories: Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Esophageal Atresia

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Aliases & Descriptions for Esophageal Atresia:

Name: Esophageal Atresia 11 48 27 50 39 13 68
Congenital Imperforate Esophagus 11
Congenital Atresia of Esophagus 11
 
Imperforate Esophagus 11
Oesophageal Atresia 11

Classifications:



External Ids:

Disease Ontology11 DOID:10485
ICD1030 Q39.0
MeSH39 D004933
NCIt45 C87072

Summaries for Esophageal Atresia

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Wikipedia:71 Esophageal atresia (or Oesophageal atresia) is a congenital medical condition (birth defect) that... more...

MalaCards based summary: Esophageal Atresia, also known as congenital imperforate esophagus, is related to esophageal atresia/tracheoesophageal fistula and tracheoesophageal fistula with or without esophageal atresia. An important gene associated with Esophageal Atresia is SHH (Sonic Hedgehog), and among its related pathways are Tgif disruption of Shh signaling and Development_Hedgehog and PTH signaling pathways in bone and cartilage development. Affiliated tissues include lung, colon and heart, and related mouse phenotypes are taste/olfaction and hearing/vestibular/ear.

Related Diseases for Esophageal Atresia

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Diseases related to Esophageal Atresia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 110)
idRelated DiseaseScoreTop Affiliating Genes
1esophageal atresia/tracheoesophageal fistula12.4
2tracheoesophageal fistula with or without esophageal atresia12.0
3anophthalmia esophageal atresia cryptorchidism11.9
4esophageal atresia coloboma talipes11.9
5anophthalmia-esophageal atresia-genital abnormalities syndrome11.9
6microphthalmia, syndromic 311.8
7tracheoesophageal fistula11.8
8vater/vacterl association11.4
9esophagitis11.0
10fanconi anemia, complementation group b10.9
11arroyo garcia cimadevilla syndrome10.9
12anosmia, isolated congenital10.2GLI3, SHH
13cloacal exstrophy10.2GLI3, LPP
14congenital diaphragmatic hernia10.2
15gastroesophageal reflux10.1
16rhabdomyosarcoma, embryonal, 210.1MYCN, SHH
17cornelia de lange syndrome 510.1CHD7, SHH, SOX2
18tracheomalacia10.1
19pulmonary atresia with intact ventricular septum10.1CHD7, EFTUD2, SHH
20thyroid dyshormonogenesis 310.1CHD7, FOXF1
21intellectual developmental disorder with persistence of fetal hemoglobin10.1GLI2, GLI3
22aica-ribosiduria due to atic deficiency10.1GLI3, NOG
23nodular goiter10.1GLI3, MYCN, SOX2
24t cell immunodeficiency primary10.1GLI3, NOG
25duodenitis10.1
26polydactyly, preaxial, type iv10.0GLI2, GLI3
27polydactyly, postaxial, types a1 and b10.0GLI2, GLI3, SHH
28breasts and/or nipples, aplasia or hypoplasia of, 210.0GLI2, GLI3, SHH
29duodenal atresia10.0
30horner's syndrome10.0GLI2, GLI3, SHH
31orchitis10.0GLI2, GLI3, SHH
32imperforate anus10.0
33microphthalmia10.0
34hypertrophic pyloric stenosis10.0
35pyloric stenosis10.0
36right aortic arch10.0
37colorectal cancer, hereditary nonpolyposis, type 210.0GLI2, SHH
38tricho odonto onychodysplasia syndactyly dominant type10.0CHD7, GLI3, NOG, SHH
39malignant oculomotor nerve tumor9.9FOXF1, SHH
40heart disease9.9
41pharyngitis9.9
42laryngitis9.9
43situs inversus9.9
44dysphagia9.9
45extragonadal germ cell cancer9.9GLI2, GLI3, MYCN, SHH
46digeorge syndrome9.8
47lung agenesis9.8
48tracheal stenosis9.8
49tricuspid atresia9.7
50omphalocele9.7

Graphical network of the top 20 diseases related to Esophageal Atresia:



Diseases related to esophageal atresia

Symptoms & Phenotypes for Esophageal Atresia

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MGI Mouse Phenotypes related to Esophageal Atresia according to GeneCards Suite gene sharing:

41 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053949.7GLI3, NOG, SHH, SOX2
2MP:00053778.8CHD7, GLI2, GLI3, NOG, SHH, SOX2
3MP:00053718.5CHD7, GLI2, GLI3, MYCN, NOG, SHH
4MP:00053828.4CHD7, GLI2, GLI3, MYCN, NOG, SHH
5MP:00028738.4GLI2, GLI3, MYCN, NOG, SHH, SOX2
6MP:00053918.2CHD7, GLI2, GLI3, MYCN, NOG, SHH
7MP:00053908.1CHD7, GLI2, GLI3, MYCN, NOG, SHH
8MP:00053698.0CHD7, FOXF1, GLI2, MYCN, NOG, SHH
9MP:00053807.9CHD7, FOXF1, GLI2, GLI3, MYCN, NOG
10MP:00107717.9GAL, GLI2, GLI3, NOG, SHH, SOX2
11MP:00053887.6CHD7, FOXF1, GLI2, GLI3, MYCN, NOG
12MP:00053817.5CHD7, FOXF1, GLI2, GLI3, MYCN, NOG
13MP:00036317.4CHD7, GAL, GLI2, GLI3, MYCN, NOG
14MP:00053796.9CHD7, FANCB, GAL, GLI2, GLI3, NOG
15MP:00107686.8CHD7, EFTUD2, FOXF1, GLI2, GLI3, LPP
16MP:00053786.7CHD7, FANCB, GAL, GLI2, GLI3, MYCN
17MP:00053896.3CHD7, FANCB, GAL, GLI2, GLI3, LPP
18MP:00053846.1CHD7, FANCB, GAL, GLI2, GLI3, LPP
19MP:00053765.9CHD7, EFTUD2, FANCB, GAL, GLI2, GLI3

Drugs & Therapeutics for Esophageal Atresia

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Drugs for Esophageal Atresia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Omeprazoleapproved, investigational, vet_approvedPhase 334873590-58-64594
Synonyms:
( -)-Omeprazole
(-)-Omeprazole
(S)-(-)-Omeprazole
(S)-Omeprazole
119141-89-8
131959-78-9
172964-80-6
2,3,5-Trimethylpyridine/Omeprazole
2-(((3,5-Dimethyl-4-methoxy-2-pyridyl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole
2-({[3,5-dimethyl-4-(methyloxy)pyridin-2-yl]methyl}sulfinyl)-5-(methyloxy)-1H-benzimidazole
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
73590-58-6
AC-401
AC1L1IIJ
AGI-010
AKOS005066653
AULCER
Antra
Antra MUPS
Audazol
Aulcer
Axagon
BIDD:GT0189
BPBio1_000425
BRD-A55962179-001-04-9
BSPBio_000385
Belmazol
Bio-0888
C07324
CAS-73590-58-6
CCRIS 7099
CHEBI:519601
CHEBI:7772
CHEMBL1503
CID4594
CPD000058847
Ceprandal
D00455
DB00338
DB00736
DM-3458
Danlox
Demeprazol
Desec
Dizprazol
Dudencer
Elgam
Emeproton
Emilok
Epirazole
Erbolin
Esomeprazole
Esomperazole
Esopral
Exter
Gasec
Gastrimut
Gastroloc
Gibancer
H 168-68
H 168/68
H-168/68
H168/68
HMS1528I05
HMS1569D07
HMS2052G17
HMS2090E16
HMS2090F11
HSDB 3575
I06-0705
IDI1_032523
Indurgan
Inhibitron
Inhipump
LS-7629
Lensor
Logastric
Lomac
Losec
Losec, Omesec, Prilosec, Zegerid, Omeprazole
Lucen
MLS000069373
MLS001076112
MLS001424148
Maybridge4_002645
Mepral
Miol
Miracid
MolPort-003-666-741
MolPort-003-807-515
MolPort-003-849-702
Mopral
Morecon
NCGC00016925-01
 
NCGC00016925-02
NCGC00021522-03
NCGC00021522-04
NCGC00021522-05
Nexiam
Nexium
Nexium IV
Nilsec
Nopramin
Nuclosina
O0359
O104_SIGMA
OMEP
OMP
OMZ
Ocid
Olexin
Olit
Omapren
Omebeta
Omebeta 20
Omed
Omegast
Omepradex
Omepral
Omeprazol
Omeprazol [INN-Spanish]
Omeprazole
Omeprazole (JAN/USP/INN)
Omeprazole Pellets
Omeprazole [USAN:INN:BAN:JAN]
Omeprazole delayed-release
Omeprazole magnesium
Omeprazolum
Omeprazolum [INN-Latin]
Omeprazon
Omeprazone
Omeprol
Omesek
Omez
Omezol
Omezolan
Omid
Omisec
Omizac
Ompanyt
Ortanol
Osiren
Ozoken
Paprazol
Parizac
Pepticum
Pepticus
Peptilcer
Prazentol
Prazidec
Prazolit
Prestwick0_000493
Prestwick1_000493
Prestwick2_000493
Prestwick3_000493
Prestwick_808
Prilosec
Prilosec (TN)
Prilosec OTC
Procelac
Proclor
Prysma
Ramezol
Regulacid
Result
S1389_Selleck
SAM001246900
SAN-15
SMR000058847
SPBio_002306
STK623746
Sanamidol
Secrepina
TL8005099
Tedec Ulceral
UNII-KG60484QX9
UPCMLD-DP075
UPCMLD-DP075:001
Ulceral
Ulcesep
Ulcometion
Ulcozol
Ulcsep
Ulsen
Ultop
Ulzol
Victrix
Zefxon
Zegerid
Zepral
Zimor
Zoltum
esomeprazol
omeprazole
2AntacidsPhase 31842
3
Proton pump inhibitorsPhase 31123
Synonyms:
 
PPIs
4Anti-Ulcer AgentsPhase 31842
5Gastrointestinal AgentsPhase 38402
6Pharmaceutical SolutionsPhase 28192
7Parenteral Nutrition SolutionsPhase 2160
8Soybean oil, phospholipid emulsionPhase 276
9Fat Emulsions, IntravenousPhase 297
10Omega 3 Fatty AcidNutraceuticalPhase 21018
11Soy BeanNutraceuticalPhase 2554
12
Nitric Oxideapproved61710102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
13
Ropivacaineapproved79384057-95-471273, 175805
Synonyms:
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
(S)-(−)-1-propyl-2',6'-pipecoloxylidide
(S)-ropivacaine
84057-95-4
98717-15-8
AC1L41QM
AC1L41QN
BIDD:GT0203
C07532
C17H26N2O.HCl
CHEBI:8890
CHEMBL1077896
CID175804
CID175805
CPD000469137
D08490
I14-176
L-N-n-propylpipecolic acid-2,6-xylidide
LS-113954
 
MLS001401363
MolPort-003-983-292
NCGC00164597-01
Naropin
Naropin (TN)
ROPIVACAINE HCl
Ropivacaina
Ropivacaina [INN-Spanish]
Ropivacaina [Spanish]
Ropivacaine
Ropivacaine [INN]
Ropivacaine hydrochloride
Ropivacaine monohydrochloride
Ropivacainum
Ropivacainum [INN-Latin]
S-Ropivacaine
SAM001246524
SMR000469137
ST51051452
ropivacaine monohydrochloride,
ropivacaine monohydrochloride, (S)-isomer
14Vitamins5282
15Trace Elements6001
16Micronutrients6001
17Peripheral Nervous System Agents23689
18Central Nervous System Depressants13403
19Anesthetics, Local3492
20Anesthetics9596
21lysineNutraceutical98

Interventional clinical trials:

(show all 13)
idNameStatusNCT IDPhase
1Rectal and Oral Omeprazole Treatment of Reflux Disease in Infants.Unknown statusNCT00226044Phase 3
2Omega 3 Fatty Acid Treatment for Pediatric Musculoskeletal HealthNot yet recruitingNCT03127345Phase 2
3Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood GasesUnknown statusNCT01467245
4Esophageal Atresia: Metaplasia, BarrettCompletedNCT02495051
5Chewing in Children With Repaired Esophageal Atresia-tracheoesophageal FistulaCompletedNCT03026491
6Study in Children With the Diagnosis of Congenital Diaphragmatic Hernia (CDH) and Oesophageal Atresia (EA)CompletedNCT02466451
7Determination of Lysine Requirement in the Parenterally Fed NeonateCompletedNCT00779753
8National Register of Oesophageal AtresiaRecruitingNCT02883725
9Dumping Syndrome After Operation of Esophageal Atresia Type IIIRecruitingNCT02525705
10Innovative Approaches to Assessment of Pain Control and Sedation in the NICURecruitingNCT03057782
11Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic SurgeryEnrolling by invitationNCT02033772
12Individualized Management for Long Gap Esophageal AtresiaNot yet recruitingNCT03023865
13Blood Ropivacaine Concentrations Following Nerve Block in Infants and Toddlers Undergoing Esophageal Atresia RepairNot yet recruitingNCT02860091

Search NIH Clinical Center for Esophageal Atresia


Cochrane evidence based reviews: esophageal atresia

Genetic Tests for Esophageal Atresia

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Genetic tests related to Esophageal Atresia:

id Genetic test Affiliating Genes
1 Esophageal Atresia27

Anatomical Context for Esophageal Atresia

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MalaCards organs/tissues related to Esophageal Atresia:

36
Lung, Colon, Heart, Trachea, Brain, Pancreas, Bone

Publications for Esophageal Atresia

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Articles related to Esophageal Atresia:

(show top 50)    (show all 717)
idTitleAuthorsYear
1
Brain Oxygenation During Thoracoscopic Repair of Long Gap Esophageal Atresia. (28058473)
2017
2
Thoracoscopic surgery for esophageal atresia. (28064362)
2017
3
Risk Factors for Anastomotic Strictures after Esophageal Atresia Repair: Prophylactic Proton Pump Inhibitors Do Not Reduce the Incidence of Strictures. (27769086)
2017
4
New Variant of Esophageal Atresia. (28083495)
2017
5
Esophageal Atresia with or without Tracheoesophageal Fistula (EA/TEF): Association of Different EA/TEF Subtypes with Specific Co-occurring Congenital Anomalies and Implications for Diagnostic Workup. (28061520)
2017
6
Dilations of anastomotic strictures over time after repair of esophageal atresia. (27844168)
2017
7
Quality of Life after Surgical Treatment for Esophageal Atresia: Long-Term Outcome of 154 Patients. (28061521)
2017
8
Two-Stage Thoracoscopic Repair of Long-Gap Esophageal Atresia Using Internal Traction Is Safe and Feasible. (27792528)
2017
9
Preliminary Study of Video-Based Pediatric Endoscopic Surgical Skill Assessment Using a Neonatal Esophageal Atresia/Tracheoesophageal Fistula Model. (27858521)
2017
10
Prevalence, characteristics, and survival of children with esophageal atresia: A 32-year population-based study including 1,417,724 consecutive newborns. (26931365)
2016
11
Ulcerative Colitis in Colonic Interposition for Esophageal Atresia. (27847835)
2016
12
A new approach for the management of esophageal atresia without tracheo-esophageal fistula. (27365910)
2016
13
Esophageal atresia with tracheoesophageal fistula in a patient with 7q35-36.3 deletion including SHH gene. (27614115)
2016
14
Perioperative management and outcomes of esophageal atresia and tracheoesophageal fistula. (27993359)
2016
15
Evaluation of the intraoperative risk factors for esophageal anastomotic complications after primary repair of esophageal atresia with tracheoesophageal fistula. (27461430)
2016
16
Impaired VEGF Signaling in Lungs with Hypoplastic Esophageal Atresia and Effects on Branching Morphogenesis. (27372649)
2016
17
An Unusual Case of Foreign Body Lodged in the Laryngopharynx of Neonate with Esophageal Atresia. (26793600)
2016
18
Role of glycopyrrolate in healing of anastomotic dehiscence after primary repair of esophageal atresia in a low resource setting-A randomized controlled study. (27939204)
2016
19
Thoracoscopic repair of esophageal atresia with tracheoesophageal fistula: Basics of technique and its nuances. (27365905)
2016
20
Thoracoscopic Esophageal Atresia with Tracheoesophageal Fistula Repair: The First Iranian Group Report, Passing the Learning Curve. (27471677)
2016
21
Environmental factors in the etiology of isolated and nonisolated esophageal atresia in a Chinese population: A case-control study. (27494675)
2016
22
Routine post-operative esophagram is not necessary after repair of esophageal atresia. (28057296)
2016
23
Weekday vs. weekend repair of esophageal atresia and tracheoesophageal fistula. (26932247)
2016
24
Late Complication of Esophageal Atresia/Tracheoesophageal Fistula Repair. (27139297)
2016
25
Pure Esophageal Atresia without a Gap: An Unusual Variant. (27123408)
2016
26
Is fundoplication required after the Foker procedure for long gap esophageal atresia? (28063681)
2016
27
Validation of an inanimate low cost model for training minimal invasive surgery (MIS) of esophageal atresia with tracheoesophageal fistula (AE/TEF) repair. (27530889)
2016
28
An approximation technique for primary anastomosis (Gazi method) in selected cases of long gap esophageal atresia. (26961289)
2016
29
Prevalence of Barrett Esophagus in Adolescents and Young Adults With Esophageal Atresia. (27163954)
2016
30
Swallowing Dysfunction and Quality of Life in Adults With Surgically Corrected Esophageal Atresia/Tracheoesophageal Fistula as Infants: Forty Years of Follow-up. (27607100)
2016
31
Transition of Patients with Esophageal Atresia to Adult Care: Results of a Transition-Specific Education Program. (27522121)
2016
32
An Unusual Passage of a Nasogastric Tube in Esophageal Atresia. (26794469)
2016
33
The management of newborns with esophageal atresia and right aortic arch: A systematic review or still unsolved problem. (26592954)
2016
34
Posttraumatic Stress Reactions in Parents of Children Esophageal Atresia. (26953589)
2016
35
Gastric tube esophageal reconstruction in children with esophageal atresia and caustic stricture Study of clinical value based on 25 single-center. Centre experience. (27872426)
2016
36
Coping strategies used by children and adolescents born with esophageal atresia - a focus group study obtaining the child and parent perspective. (27469614)
2016
37
Assessment of Clinical Symptoms and Multichannel Intraluminal Impedance and pH Monitoring in Children After Thoracoscopic Repair of Esophageal Atresia and Distal Tracheoesophageal Fistula. (28028956)
2016
38
Functional residual capacity and lung clearance index in infants treated for esophageal atresia and tracheoesophageal fistula. (26607967)
2016
39
Outcomes of thoracoscopy versus thoracotomy for esophageal atresia with tracheoesophageal fistula repair: A PRISMA-compliant systematic review and meta-analysis. (27472740)
2016
40
Long Upper Pouch in Esophageal Atresia: A Rare Variant. (26793598)
2016
41
Esophageal Atresia: Future Directions for Research on the Digestive Tract. (27533315)
2016
42
Long-term morbidity in adolescents and young adults with surgically treated esophageal atresia. (28028638)
2016
43
Repair of esophageal atresia with proximal fistula using endoscopic magnetic compression anastomosis (magnamosis) after staged lengthening. (27012861)
2016
44
Fluoroscopic balloon dilatation for anastomotic strictures in patients with esophageal atresia: A fifteen-year single centre UK experience. (27032608)
2016
45
END-TO-END VERSUS END-TO-SIDE ANASTOMOSIS IN THE TREATMENT OF ESOPHAGEAL ATRESIA OR TRACHEO-ESOPHAGEAL FISTULA. (27120740)
2016
46
Creation of an animal model for long gap pure esophageal atresia. (27838766)
2016
47
Esophageal Atresia with Tracheoesophageal Fistula. (27387366)
2016
48
Categorization and repair of recurrent and acquired tracheoesophageal fistulae occurring after esophageal atresia repair. (27616617)
2016
49
Long-term pulmonary function in esophageal atresia-A case-control study. (27164020)
2016
50
An assessment of quality of life of operated cases of esophageal atresia in the community. (27365908)
2016

Variations for Esophageal Atresia

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Expression for genes affiliated with Esophageal Atresia

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Search GEO for disease gene expression data for Esophageal Atresia.

Pathways for genes affiliated with Esophageal Atresia

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GO Terms for genes affiliated with Esophageal Atresia

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Cellular components related to Esophageal Atresia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ciliary baseGO:00975469.6GLI2, GLI3

Biological processes related to Esophageal Atresia according to GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idNameGO IDScoreTop Affiliating Genes
1embryonic skeletal system developmentGO:004870610.7NOG, SHH
2embryonic hindlimb morphogenesisGO:003511610.7CHD7, SHH
3artery developmentGO:006084010.7GLI3, SHH
4embryonic morphogenesisGO:004859810.6GLI3, SHH
5embryonic organ developmentGO:004856810.6GLI3, SHH
6metanephros developmentGO:000165610.6GLI3, SHH
7negative regulation of alpha-beta T cell differentiationGO:004663910.6GLI3, SHH
8negative thymic T cell selectionGO:004506010.6GLI3, SHH
9neuron fate commitmentGO:004866310.6GLI3, SHH
10oligodendrocyte differentiationGO:004870910.6GLI3, SHH
11positive regulation of alpha-beta T cell differentiationGO:004663810.6GLI3, SHH
12positive regulation of neuroblast proliferationGO:000205210.6GLI3, SHH
13positive regulation of protein import into nucleusGO:004230710.6GLI3, SHH
14embryonic foregut morphogenesisGO:004861710.6FOXF1, SHH
15epithelial tube branching involved in lung morphogenesisGO:006044110.6FOXF1, SHH
16lung lobe morphogenesisGO:006046310.6FOXF1, SHH
17somite developmentGO:006105310.6NOG, SHH
18pancreas developmentGO:003101610.6FOXF1, SHH
19negative regulation of astrocyte differentiationGO:004871210.5MYCN, NOG
20dorsal/ventral neural tube patterningGO:002190410.5GLI2, SHH
21T cell differentiation in thymusGO:003307710.5GLI3, SHH
22hindbrain developmentGO:003090210.5GLI2, SHH
23renal system developmentGO:007200110.5FOXF1, SHH
24respiratory tube developmentGO:003032310.5FOXF1, SHH
25osteoblast developmentGO:000207610.5GLI2, SHH
26positive regulation of T cell differentiation in thymusGO:003308910.5GLI2, SHH
27trachea developmentGO:006043810.5FOXF1, SHH
28prostatic bud formationGO:006051310.4GLI2, NOG
29mammary gland developmentGO:003087910.4GLI2, GLI3
30smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferationGO:002193810.4GLI2, SHH
31negative regulation of cell differentiationGO:004559610.4GLI3, NOG, SHH
32proximal/distal pattern formationGO:000995410.4GLI2, GLI3
33forebrain developmentGO:003090010.3GLI3, SHH, SOX2
34lung morphogenesisGO:006042510.3FOXF1, NOG, SHH
35inner ear developmentGO:004883910.3GLI3, SHH, SOX2
36camera-type eye developmentGO:004301010.3CHD7, GLI3, SHH
37regulation of gene expressionGO:001046810.3GLI3, SHH, SOX2
38palate developmentGO:006002110.3CHD7, GLI3, SHH
39negative regulation of gene expressionGO:001062910.3MYCN, NOG, SHH
40smoothened signaling pathway involved in dorsal/ventral neural tube patterningGO:006083110.3GLI2, GLI3
41smoothened signaling pathway involved in spinal cord motor neuron cell fate specificationGO:002177610.3GLI2, GLI3
42smoothened signaling pathway involved in ventral spinal cord interneuron specificationGO:002177510.3GLI2, GLI3
43embryonic digestive tract morphogenesisGO:004855710.2FOXF1, GLI3, SHH
44osteoblast differentiationGO:000164910.1GLI2, NOG, SOX2
45pituitary gland developmentGO:002198310.1GLI2, NOG, SOX2
46positive regulation of mesenchymal cell proliferationGO:000205310.1FOXF1, MYCN, SHH
47anatomical structure developmentGO:004885610.1GLI2, GLI3, SHH
48anterior/posterior pattern specificationGO:000995210.1GLI2, GLI3, SHH
49developmental growthGO:004858910.1GLI2, GLI3, SHH
50hindgut morphogenesisGO:000744210.1GLI2, GLI3, SHH

Molecular functions related to Esophageal Atresia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1promoter-specific chromatin bindingGO:199084110.3CHD7, GLI2
2sequence-specific DNA bindingGO:00435659.6FOXF1, GLI2, GLI3, SOX2
3transcription regulatory region DNA bindingGO:00442129.2FOXF1, GLI2, SOX2
4transcription factor activity, sequence-specific DNA bindingGO:00037009.0FOXF1, GLI2, GLI3, MYCN, SOX2

Sources for Esophageal Atresia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
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41MGI
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46NDF-RT
49NINDS
50Novoseek
52OMIM
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63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet