MCID: ESP002
MIFTS: 42

Esophageal Varix malady

Rare diseases, Cardiovascular diseases categories
Download this MalaCard

Summaries for Esophageal Varix

About this section


Fully expand this MalaCard
MalaCards based summary: Esophageal Varix, also known as esophageal varices, is related to liver cirrhosis and hypertension. An important gene associated with Esophageal Varix is SST (somatostatin), and among its related pathways are Selenium Pathway and FOXA2 and FOXA3 transcription factor networks. The compounds amphetamine and gelofusine have been mentioned in the context of this disorder. Affiliated tissues include liver, and related mouse phenotypes are digestive/alimentary and normal.

Aliases & Classifications for Esophageal Varix

About this section

Esophageal Varix, Aliases & Descriptions:

Name: Esophageal Varix 8 10
Esophageal Varices 8 42 44 62
Bleeding Esophageal Varices 8 44 62
Esophageal Varices Without Mention of Bleeding 8 62
Esophageal Varices Without Bleeding 8 62
 
Esophageal Varices with Bleeding 8 62
Esophageal Varices in Disease Classified Elsewhere, with Bleeding 8
Esophageal Varices with Bleeding in Disease Ec 8
Bleeding Oesophageal Varices 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Cardiovascular diseases


External Ids:

Disease Ontology8 DOID:112
NCIt39 C78282
ICD9CM27 456.0

Related Diseases for Esophageal Varix

About this section

Graphical network of the top 20 diseases related to Esophageal Varix:



Diseases related to esophageal varix

Symptoms for Esophageal Varix

About this section

Drugs & Therapeutics for Esophageal Varix

About this section

Drug clinical trials:

Search ClinicalTrials for Esophageal Varix

Search NIH Clinical Center for Esophageal Varix

Genetic Tests for Esophageal Varix

About this section

Anatomical Context for Esophageal Varix

About this section

MalaCards organs/tissues related to Esophageal Varix:

32
Liver

Animal Models for Esophageal Varix or affiliated genes

About this section

MGI Mouse Phenotypes related to Esophageal Varix:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.5ALB, SST, F2
2MP:00028737.9EVL, ALB, SST, F2
3MP:00053767.7F2, SST, ALB, EVL

Publications for Esophageal Varix

About this section

Articles related to Esophageal Varix:

(show all 30)
idTitleAuthorsYear
1
Gastrointestinal: Hepatocellular carcinoma in an esophageal varix. (25404106)
2014
2
Esophageal varix predictive performance of lower esophageal Doppler signals during the swallowing process. (24951299)
2014
3
Stroke after percutaneous transhepatic variceal obliteration of esophageal varix in Caroli syndrome. (24348664)
2013
4
Extended hemangioma from pharynx to esophagus that could be misdiagnosed as an esophageal varix on endoscopy. (24164602)
2013
5
Vascular lesion in an adult mimicking esophageal varix. (23159366)
2013
6
Variceal transection of esophageal varix using the ESD method: new treatment technique for esophageal varix (with video). (22365437)
2012
7
Achalasia cardia with esophageal varix managed with endoscopic ultrasound-guided botulinum toxin injection. (22180005)
2011
8
Hepatic veno-occlusive disease followed by esophageal varix rupture after hematopoietic stem cell transplantation in a 4-year-old boy with stage 4 neuroblastoma. (18176184)
2008
9
Ultrasound system to measure esophageal varix pressure: an in vitro validation study. (15626729)
2005
10
Portal venous flow pattern as a useful tool for predicting esophageal varix bleeding in cirrhotic patients. (15986878)
2005
11
The banding of an esophageal varix. (16151545)
2005
12
Three-dimensional esophageal varix model quantification of variceal volume by high-resolution endoluminal US. (10882970)
2000
13
White ball sign after ligation of the esophageal varix bleeding point. (10625824)
2000
14
Surgery for esophageal varix bleeding in cirrhotic patients during the era of liver transplants. (10500632)
1999
15
Two cases of esophageal varix caused by local hyperdynamic state of gastric arteries. (10430342)
1999
16
Post-inflammatory polyps of esophagus: a rare sequela of endoscopic injection sclerotherapy for esophageal varix. (8293932)
1993
17
Results of experimental endoscopic esophageal varix ligation. (3341642)
1988
18
Solitary esophageal varix simulating a neoplasm. (3248091)
1988
19
Endoscopic esophageal varix ligation: preliminary clinical experience. (3259195)
1988
20
Endoscopic esophageal varix ligation: technique and preliminary results in children. (3266244)
1988
21
Critical evaluation of a pressure-sensitive capsule for measurement of esophageal varix pressure. Studies in vitro and in canine mesenteric vessels. (3557007)
1987
22
Esophageal varix hemorrhage and sclerotherapy--animal studies. (3519190)
1986
23
Idiopathic esophageal varix. (6602526)
1983
24
THORACIC DUCT CANNULATION FOR CONTROL OF ESOPHAGEAL VARIX HEMORRHAGE. A PRELIMINARY REPORT. (14226387)
1965
25
GASTRIC SECRETION IN LIVER DISEASE AND ESOPHAGEAL VARIX RUPTURE. (14052010)
1963
26
PATHOGENESIS OF ESOPHAGEAL VARIX RUPTURE. A STUDY BASED ON GROSS AND MICROSCOPIC EXAMINATION OF THE ESOPHAGUS AT THE TIME OF BLEEDING. (14042680)
1963
27
Pathogenesis of esophageal varix rupture. (13762024)
1961
28
The use of surgical pituitrin in the control of esophageal varix bleeding; an experimental study and report of two cases. (13324606)
1956
29
Severe bleeding of an esophageal varix controlled by oxycel. (18132775)
1949
30
The esophageal varix; a report of 115 cases. (20266943)
1947

Variations for Esophageal Varix

About this section

Expression for genes affiliated with Esophageal Varix

About this section
Expression patterns in normal tissues for genes affiliated with Esophageal Varix

Search GEO for disease gene expression data for Esophageal Varix.

Pathways for genes affiliated with Esophageal Varix

About this section

Pathways related to Esophageal Varix according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
thioredoxin pathway37
9.0ALB, F2
29.0ALB, F2

Compounds for genes affiliated with Esophageal Varix

About this section

Compounds related to Esophageal Varix according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1amphetamine44 50 1111.6SST, F2
2gelofusine449.5SST, ALB
35-hydroxytryptamine449.5F2, SST
4dtpa449.5SST, ALB
5captopril44 61 50 28 1113.4ALB, SST
6naloxone44 28 50 1112.4SST, ALB
7cefotetan44 1110.4F2, ALB
8dextran 70449.4ALB, F2
9hepaplastin449.4F2, ALB
10cefoperazone44 1110.4ALB, F2
11acenocoumarol44 50 1111.4ALB, F2
12phenprocoumon44 50 1111.4F2, ALB
13phenylbutazone44 1110.4F2, ALB
14hydroxyethyl starch449.4F2, ALB
15antipyrine44 1110.4ALB, F2
16warfarin44 50 24 1112.3ALB, F2
17kininogen449.3ALB, F2
18thyroxine44 2410.3ALB, SST
19polyethylene glycol449.3F2, ALB
20homocysteine44 2410.3ALB, F2
21epinephrine44 24 1111.2SST, F2
22citrate449.2ALB, F2
23hyaluronic acid44 2410.1ALB, F2
24histamine44 28 2411.1ALB, SST
25calcitriol44 61 24 1112.1ALB, F2
26methotrexate50 44 1111.0F2, ALB
27terlipressin44 119.9ALB, SST, F2
28lactate448.8ALB, SST, F2
29fibrinogen448.7ALB, F2

GO Terms for genes affiliated with Esophageal Varix

About this section

Cellular components related to Esophageal Varix according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:0725628.9ALB, F2
2extracellular regionGO:0055768.5ALB, SST, F2
3extracellular spaceGO:0056158.2ALB, SST, F2

Biological processes related to Esophageal Varix according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet activationGO:0301689.0ALB, F2
2response to nutrientGO:0075848.8ALB, SST
3cell surface receptor signaling pathwayGO:0071668.7EVL, SST, F2

Products for genes affiliated with Esophageal Varix

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Esophageal Varix

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet