Aliases & Classifications for Esophageal Varix

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Esophageal Varix, Aliases & Descriptions:

Name: Esophageal Varix 9 11
Esophageal Varices 9 41 43 60
Bleeding Esophageal Varices 9 43 60
Esophageal Varices Without Bleeding 9 60
Esophageal Varices in Disease Classified Elsewhere, with Bleeding 9
 
Esophageal Varices with Bleeding in Disease Ec 9
Esophageal Varices Without Mention of Bleeding 9
Esophageal Varices with Bleeding 9
Bleeding Oesophageal Varices 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


External Ids:

Disease Ontology9 DOID:112
ICD9CM27 456.0
NCIt38 C78282

Summaries for Esophageal Varix

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MalaCards based summary: Esophageal Varix, also known as esophageal varices, is related to portal hypertension and alcoholic liver cirrhosis. An important gene associated with Esophageal Varix is SST (somatostatin), and among its related pathways are Selenium Pathway and FOXA2 and FOXA3 transcription factor networks. The compounds amphetamine and gelofusine have been mentioned in the context of this disorder. Affiliated tissues include liver, and related mouse phenotypes are digestive/alimentary and normal.

Related Diseases for Esophageal Varix

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Diseases related to Esophageal Varix via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 95)
idRelated DiseaseScoreTop Affiliating Genes
1portal hypertension30.8F2, SST, ALB
2alcoholic liver cirrhosis30.5F2, ALB
3liver cirrhosis30.4F2, ALB
4primary biliary cirrhosis30.4ALB, F2
5hepatitis b30.4ALB, F2
6pancreatitis30.3ALB, SST
7hepatitis30.3ALB, F2
8hypersplenism30.2EVL, F2
9hepatorenal syndrome30.2F2, ALB
10alcoholic hepatitis30.2F2, ALB
11liver disease29.9ALB, SST, F2
12esophagitis10.9
13biliary atresia10.4
14myelofibrosis10.4
15blindness10.3
16wolman disease10.3
17dysfibrinogenemia10.3F2
18splenic artery aneurysm10.3
19aneurysm10.3
20pulmonary hypertension10.2
21gaucher's disease10.2
22hepatic coma10.2
23felty's syndrome10.2
24mediastinitis10.2
25superior vena cava syndrome10.2
26budd-chiari syndrome10.1
27hepatocellular carcinoma10.1
28glycogen storage disease iv10.1
29adams-oliver syndrome 510.1
30wilson disease10.1
31neuroblastoma10.1
32polycystic kidney and hepatic disease10.1
33cirrhosis, cryptogenic10.1
34hemangioma10.1
35hematopoietic stem cell transplantation10.1
36hereditary hemorrhagic telangiectasia10.1
37cystic echinococcosis10.1
38achalasia10.1
39alveolar echinococcosis10.1
40adams-oliver syndrome10.1
41homocystinuria due to cbs deficiency10.1
42short bowel syndrome10.1SST, ALB
43diarrhea10.1SST, ALB
44adult respiratory distress syndrome10.1
45behcet's disease10.1
46duodenal ulcer10.1
47caroli disease10.1
48angiodysplasia10.1
49gastric ulcer10.1
50portal vein thrombosis10.1

Graphical network of the top 20 diseases related to Esophageal Varix:



Diseases related to esophageal varix

Symptoms for Esophageal Varix

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Drugs & Therapeutics for Esophageal Varix

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Drug clinical trials:

Search ClinicalTrials for Esophageal Varix

Search NIH Clinical Center for Esophageal Varix

Genetic Tests for Esophageal Varix

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Anatomical Context for Esophageal Varix

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MalaCards organs/tissues related to Esophageal Varix:

31
Liver

Animal Models for Esophageal Varix or affiliated genes

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MGI Mouse Phenotypes related to Esophageal Varix:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.5ALB, F2, SST
2MP:00028737.9F2, SST, ALB, EVL
3MP:00053767.7EVL, F2, SST, ALB

Publications for Esophageal Varix

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Articles related to Esophageal Varix:

(show all 31)
idTitleAuthorsYear
1
Emergency treatment of esophageal varix incarceration in the endoscope and ligation device during endoscopic variceal rubber band ligation. (25550983)
2014
2
Gastrointestinal: Hepatocellular carcinoma in an esophageal varix. (25404106)
2014
3
Esophageal varix predictive performance of lower esophageal Doppler signals during the swallowing process. (24951299)
2014
4
Stroke after percutaneous transhepatic variceal obliteration of esophageal varix in Caroli syndrome. (24348664)
2013
5
Extended hemangioma from pharynx to esophagus that could be misdiagnosed as an esophageal varix on endoscopy. (24164602)
2013
6
Vascular lesion in an adult mimicking esophageal varix. (23159366)
2013
7
Variceal transection of esophageal varix using the ESD method: new treatment technique for esophageal varix (with video). (22365437)
2012
8
Achalasia cardia with esophageal varix managed with endoscopic ultrasound-guided botulinum toxin injection. (22180005)
2011
9
Hepatic veno-occlusive disease followed by esophageal varix rupture after hematopoietic stem cell transplantation in a 4-year-old boy with stage 4 neuroblastoma. (18176184)
2008
10
Ultrasound system to measure esophageal varix pressure: an in vitro validation study. (15626729)
2005
11
Portal venous flow pattern as a useful tool for predicting esophageal varix bleeding in cirrhotic patients. (15986878)
2005
12
The banding of an esophageal varix. (16151545)
2005
13
Three-dimensional esophageal varix model quantification of variceal volume by high-resolution endoluminal US. (10882970)
2000
14
White ball sign after ligation of the esophageal varix bleeding point. (10625824)
2000
15
Surgery for esophageal varix bleeding in cirrhotic patients during the era of liver transplants. (10500632)
1999
16
Two cases of esophageal varix caused by local hyperdynamic state of gastric arteries. (10430342)
1999
17
Post-inflammatory polyps of esophagus: a rare sequela of endoscopic injection sclerotherapy for esophageal varix. (8293932)
1993
18
Results of experimental endoscopic esophageal varix ligation. (3341642)
1988
19
Solitary esophageal varix simulating a neoplasm. (3248091)
1988
20
Endoscopic esophageal varix ligation: preliminary clinical experience. (3259195)
1988
21
Endoscopic esophageal varix ligation: technique and preliminary results in children. (3266244)
1988
22
Critical evaluation of a pressure-sensitive capsule for measurement of esophageal varix pressure. Studies in vitro and in canine mesenteric vessels. (3557007)
1987
23
Esophageal varix hemorrhage and sclerotherapy--animal studies. (3519190)
1986
24
Idiopathic esophageal varix. (6602526)
1983
25
THORACIC DUCT CANNULATION FOR CONTROL OF ESOPHAGEAL VARIX HEMORRHAGE. A PRELIMINARY REPORT. (14226387)
1965
26
GASTRIC SECRETION IN LIVER DISEASE AND ESOPHAGEAL VARIX RUPTURE. (14052010)
1963
27
PATHOGENESIS OF ESOPHAGEAL VARIX RUPTURE. A STUDY BASED ON GROSS AND MICROSCOPIC EXAMINATION OF THE ESOPHAGUS AT THE TIME OF BLEEDING. (14042680)
1963
28
Pathogenesis of esophageal varix rupture. (13762024)
1961
29
The use of surgical pituitrin in the control of esophageal varix bleeding; an experimental study and report of two cases. (13324606)
1956
30
Severe bleeding of an esophageal varix controlled by oxycel. (18132775)
1949
31
The esophageal varix; a report of 115 cases. (20266943)
1947

Variations for Esophageal Varix

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Expression for genes affiliated with Esophageal Varix

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Search GEO for disease gene expression data for Esophageal Varix.

Pathways for genes affiliated with Esophageal Varix

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Pathways related to Esophageal Varix according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
thioredoxin pathway36
9.0ALB, F2
29.0ALB, F2

Compounds for genes affiliated with Esophageal Varix

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Compounds related to Esophageal Varix according to GeneCards Suite gene sharing:

(show all 29)
idCompoundScoreTop Affiliating Genes
1amphetamine43 49 1211.6SST, F2
2gelofusine439.5SST, ALB
35-hydroxytryptamine439.5F2, SST
4dtpa439.5SST, ALB
5captopril43 59 49 28 1213.4ALB, SST
6naloxone43 28 49 1212.4SST, ALB
7cefotetan43 1210.4F2, ALB
8dextran 70439.4ALB, F2
9hepaplastin439.4F2, ALB
10cefoperazone43 1210.4ALB, F2
11acenocoumarol43 49 1211.4ALB, F2
12phenprocoumon43 49 1211.4F2, ALB
13phenylbutazone43 1210.4F2, ALB
14hydroxyethyl starch439.4F2, ALB
15antipyrine43 1210.4ALB, F2
16warfarin43 49 24 1212.3ALB, F2
17kininogen439.3ALB, F2
18thyroxine43 2410.3ALB, SST
19polyethylene glycol439.3F2, ALB
20homocysteine43 2410.3ALB, F2
21epinephrine43 24 1211.2SST, F2
22citrate439.2ALB, F2
23hyaluronic acid43 2410.1ALB, F2
24histamine43 28 2411.1ALB, SST
25calcitriol43 59 24 1212.1ALB, F2
26methotrexate49 43 1211.0F2, ALB
27terlipressin43 129.9ALB, SST, F2
28lactate438.8ALB, SST, F2
29fibrinogen438.7ALB, F2

GO Terms for genes affiliated with Esophageal Varix

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Cellular components related to Esophageal Varix according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:00725628.9ALB, F2
2extracellular regionGO:00055768.5ALB, SST, F2
3extracellular spaceGO:00056158.2ALB, SST, F2

Biological processes related to Esophageal Varix according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet activationGO:00301689.0ALB, F2
2response to nutrientGO:00075848.8ALB, SST
3cell surface receptor signaling pathwayGO:00071668.7EVL, SST, F2

Products for genes affiliated with Esophageal Varix

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  • Antibodies
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  • Antibodies
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  • Kits and Assays

Sources for Esophageal Varix

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet