MCID: ESP024
MIFTS: 59

Esophagitis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Esophagitis

MalaCards integrated aliases for Esophagitis:

Name: Esophagitis 12 29 52 42 14 69
Acute Esophagitis 12 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11963
ICD10 33 K20 K20.9
ICD9CM 35 530.1 530.10
MeSH 42 D004941
NCIt 47 C9224
UMLS 69 C0014868

Summaries for Esophagitis

MalaCards based summary : Esophagitis, also known as acute esophagitis, is related to vacterl association and choroiditis, and has symptoms including pain in esophagus (finding) An important gene associated with Esophagitis is CCL26 (C-C Motif Chemokine Ligand 26), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Budesonide and Omeprazole have been mentioned in the context of this disorder. Affiliated tissues include lung, lymph node and endothelial, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 72 Esophagitis (or oesophagitis) is inflammation of the esophagus. It may be acute or chronic. Acute... more...

Related Diseases for Esophagitis

Diseases in the Esophagitis family:

Bacterial Esophagitis Viral Esophagitis

Diseases related to Esophagitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 745)
id Related Disease Score Top Affiliating Genes
1 vacterl association 32.2 CXCL8 IL1B IL6 TGFB1
2 choroiditis 29.9 CXCL8 IL1B IL6
3 eosinophilic gastroenteritis 29.9 CXCL8 HRH2 IL1B PTGS2
4 lymphoma 29.8 IL13 IL1B IL5 IL6
5 hidradenitis 29.7 CXCL8 IL1B PTGS2
6 acute pancreatitis 29.7 CXCL8 IL1B IL6 PTGS2
7 pulmonary embolism 29.7 CXCL8 IL1B IL6
8 churg-strauss syndrome 29.5 CXCL8 IL1B IL5
9 hidradenitis suppurativa 29.2 CCL11 CXCL8
10 sinusitis 28.9 CXCL8 DSG1 IL1B TGFB1
11 rheumatoid arthritis 28.9 CXCL8 IL1B IL6 PTGS2 TGFB1
12 epidermolysis bullosa 28.5 CCL11 DSG1 IL13 IL5 TSLP
13 colon adenocarcinoma 28.4 CCL11 CXCL8 IL1B IL5 IL6
14 malaria 27.4 CCL11 CXCL8 IL13 IL1B IL5 IL6
15 asthma 25.2 CCL11 CCL26 CCR3 CXCL8 HRH2 IL13
16 esophageal cancer 12.4
17 tylosis with esophageal cancer 12.2
18 esophageal atresia 12.2
19 esophageal candidiasis 12.2
20 barrett esophagus/esophageal adenocarcinoma 12.1
21 esophageal disease 12.1
22 esophageal atresia/tracheoesophageal fistula 12.1
23 esophagitis, eosinophilic, 1 12.0
24 esophageal varix 12.0
25 esophageal adenosquamous carcinoma 12.0
26 esophageal adenoid cystic carcinoma 12.0
27 achalasia, familial esophageal 11.9
28 peptic esophagitis 11.9
29 esophageal tuberculosis 11.8
30 proton-pump inhibitor-responsive esophageal eosinophilia 11.8
31 viral esophagitis 11.8
32 esophageal diverticulosis 11.8
33 fungal esophagitis 11.8
34 esophageal basaloid squamous cell carcinoma 11.8
35 bacterial esophagitis 11.8
36 esophageal duplication cyst 11.8
37 congenital esophageal diverticulum 11.8
38 esophageal lipoma 11.7
39 esophageal leukoplakia 11.7
40 esophageal neuroendocrine tumor 11.7
41 anophthalmia-esophageal atresia-genital abnormalities syndrome 11.7
42 achalasia 11.7
43 gastroesophageal reflux 11.7
44 esophageal cancer, childhood 11.6
45 esophagitis, eosinophilic, 2 11.6
46 mucoepidermoid esophageal carcinoma 11.6
47 tracheoesophageal fistula with or without esophageal atresia 11.6
48 leiomyomatosis, esophageal and vulval, with nephropathy 11.6
49 feingold syndrome 1 11.6
50 crest syndrome 11.6

Comorbidity relations with Esophagitis via Phenotypic Disease Network (PDN): (show top 50) (show all 111)


Active Peptic Ulcer Disease Acute Cystitis
Acute Maxillary Sinusitis Acute Pancreatitis
Alcoholic Gastritis Allergic Rhinitis
Anxiety Disorder Atrophic Gastritis
Basilar Artery Insufficiency Benign Essential Hypertension
Benign Paroxysmal Positional Nystagmus Bronchiectasis
Bronchitis Bronchopneumonia
Cerebrovascular Disease Cholecystitis
Cholestasis Chronic Kidney Failure
Chronic Maxillary Sinusitis Chronic Myocardial Ischemia
Chronic Pulmonary Heart Disease Chronic Rhinitis
Chylomicron Retention Disease Conversion Disorder
Crohn's Disease Cystitis
Deficiency Anemia Dependent Personality Disorder
Dermatomycosis Diabetic Polyneuropathy
Duodenitis Dyskinesia of Esophagus
Dysthymic Disorder Esophageal Cancer
Esophageal Candidiasis Esophageal Disease
Esophageal Varix First-Degree Atrioventricular Block
Gallbladder Disease Gastrin Secretion Abnormality
Gastritis, Familial Giant Hypertrophic Gastroesophageal Reflux
Generalized Anxiety Disorder Generalized Atherosclerosis
Heart Disease Hepatitis
Hyperlipidemia, Familial Combined Hyperlipoproteinemia Type Iv
Hypertension, Essential Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis

Graphical network of the top 20 diseases related to Esophagitis:



Diseases related to Esophagitis

Symptoms & Phenotypes for Esophagitis

UMLS symptoms related to Esophagitis:


pain in esophagus (finding)

MGI Mouse Phenotypes related to Esophagitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.11 CCL11 CCR3 IL13 IL1B IL5 IL6
2 homeostasis/metabolism MP:0005376 10.06 PTGS2 SOD2 TGFB1 TP53 TSLP CCR3
3 digestive/alimentary MP:0005381 10.01 HRH2 IL13 IL5 IL6 PTGS2 TGFB1
4 immune system MP:0005387 10 IL13 IL1B IL5 IL6 PTGS2 SOD2
5 adipose tissue MP:0005375 9.91 DSG1 IL6 PTGS2 SOD2 TGFB1 TP53
6 integument MP:0010771 9.76 IL13 IL1B IL6 PTGS2 SOD2 TGFB1
7 neoplasm MP:0002006 9.5 IL1B IL5 IL6 PTGS2 SOD2 TGFB1
8 respiratory system MP:0005388 9.28 CCL11 CCR3 IL13 IL5 IL6 PTGS2

Drugs & Therapeutics for Esophagitis

Drugs for Esophagitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 259)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Budesonide Approved Phase 4,Phase 3,Phase 2 51333-22-3 63006 5281004
2
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 73590-58-6 4594
3
Domperidone Approved, Investigational, Vet_approved Phase 4 57808-66-9 3151
4
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
5
Pantoprazole Approved Phase 4,Phase 3,Phase 2 102625-70-7 4679
6
Dexlansoprazole Approved Phase 4,Phase 3,Phase 1,Phase 2 138530-94-6, 103577-45-3 9578005
7
Lansoprazole Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 103577-45-3 3883
8
Rabeprazole Approved, Investigational Phase 4,Phase 3,Phase 2 117976-89-3 5029
9
Esomeprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 161796-78-7, 119141-88-7 4594 9579578
10
Pemetrexed Approved, Investigational Phase 4,Phase 3,Phase 2 150399-23-8, 137281-23-3 446556 60843
11
Ranitidine Approved Phase 4,Phase 1 66357-59-3, 66357-35-5 3001055
12
Trimebutine Approved Phase 4 39133-31-8
13
Verapamil Approved Phase 4 52-53-9 2520
14
Menthol Approved Phase 4,Phase 3 2216-51-5 16666
15
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
16
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2 58-05-9 143 6006
17 Rebamipide Investigational Phase 4 90098-04-7
18
Maleic acid Experimental Phase 4 110-16-7 444266
19 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Phase 1
20 Cromolyn Sodium Phase 4
21 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
22 Anti-Allergic Agents Phase 4,Phase 3,Phase 2,Phase 1
23 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
24 Autonomic Agents Phase 4,Phase 3,Phase 2
25 Bronchodilator Agents Phase 4,Phase 3,Phase 2
26 Dermatologic Agents Phase 4,Phase 3,Phase 2
27
Fluticasone Phase 4,Phase 3,Phase 2 90566-53-3, 80474-14-2 62924 22833648
28 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
29 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
30 Hormones Phase 4,Phase 3,Phase 2,Phase 1
31 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
32 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
33 Antacids Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
34 Antiemetics Phase 4
35 Anti-Ulcer Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
36 Dopamine Agents Phase 4
37 Dopamine Antagonists Phase 4
38 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
39 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
40
Proton pump inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
41 Protective Agents Phase 4,Phase 2,Phase 1
42 Omeprazole, sodium bicarbonate drug combination Phase 4
43 Antioxidants Phase 4,Phase 2,Phase 1
44 Pepsin A Phase 4
45
Bilirubin Phase 4 635-65-4 5280352
46 Folic Acid Antagonists Phase 4,Phase 3,Phase 2
47 N-Methylaspartate Phase 4
48 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
49 Vitamin B Complex Phase 4,Phase 3,Phase 2
50 Ranitidine bismuth citrate Phase 4,Phase 1

Interventional clinical trials:

(show top 50) (show all 365)

id Name Status NCT ID Phase Drugs
1 Oral Cromolyn Sodium for the Treatment of Eosinophilic Esophagitis Unknown status NCT02371941 Phase 4 oral cromolyn sodium;Placebo
2 Dietetic Versus Topical Steroids for Pediatric Eosinophilic Esophagitis Unknown status NCT01846962 Phase 4 Budesonide;Fluticasone
3 Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD) Unknown status NCT01822106 Phase 4
4 Research of Efficient Use of Omeprazole in Combination With Domperidone in Gastroesophageal Reflux Disease of Mild to Moderate Severity Unknown status NCT02140073 Phase 4 omeprazole+domperidone SR;omeprazole
5 Intravenous (IV) Pantoprazole in Erosive Esophagitis Completed NCT00133770 Phase 4 pantoprazole
6 An Efficacy Study to Compare the Treatment Effects of Rabeprazole and Lansoprazole Depending on the Genotyping of CYP2C19 in Treating Reflux Esophagitis Completed NCT01008696 Phase 4 Rabeprazole;Lansoprazole
7 A Multicenter, Randomized, Double Blind, Double Dummy, Parallel-Group Efficacy Study Comparing 8 Weeks of Treatment With Esomeprazole Magnesium (40mg qd) to Lansoprazole (30mg qd) for the Healing of Erosive Esophagitis in Patients With Moderate or Severe Completed NCT00641602 Phase 4 Esomeprazole;Lansoprazole
8 Rate of Complete Symptom Relief, Prevention of Symptom Relapse: Grades A and B Esophagitis of Esomeprazole Therapy Completed NCT01874535 Phase 4 Esomeprazole 40 mg
9 Impact of Timing on the Efficacy of Zegerid 40 mg in Healing Reflux Esophagitis: A Pilot Study Completed NCT00693225 Phase 4 Omeprazole/sodium bicarbonate
10 NEXIUM® in the Treatment of Moderate and Severe Erosive Esophagitis Completed NCT00206180 Phase 4 esomeprazole magnesium (oral medication)
11 The Study to Evaluate Efficacy and Safety of Newrabell® Tab.(Rabeprazole Sodium) 10mg b.i.d in Refractory GERD Completed NCT01860482 Phase 4 Newrabell® Tablet 10mg
12 A Study to Evaluate REbamiPide as an Adjuvant Regimen to Heal erosIve Reflux Esophagitis Completed NCT02755753 Phase 4 Lansoprazole;Rebamipide;Rebamipide-placebo
13 Esomeprazole for Treatment of GERD in Pediatric Patients Completed NCT00228527 Phase 4 Esomeprazole (Nexium)
14 Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group Comparison of the Remission Rates of Once Daily Treatment With Esomeprazole 20mg and Lansoprazole 15mg for 6 Months in Patients Whose EE Has Been Healed Completed NCT00644735 Phase 4 Esomeprazole;Lansoprazole
15 An Open-Label Study of Once-Daily Oral Administration of Esomeprazole 40 mg in Patients With Symptoms of Gastroesophageal Reflux Disease (GERD) Completed NCT00242736 Phase 4 Esomeprazole
16 Role of Pepsin Assay in Wheezy Infants Completed NCT02685436 Phase 4 Omeprazole and domperidone
17 To Assess the Efficacy of Esomeprazole 20mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole Completed NCT01397084 Phase 4 esomeprazole 20 mg
18 Dexlansoprazole in Asian Participants With Gastroesophageal Reflux Disease Completed NCT02351960 Phase 4 Dexlansoprazole
19 The Prospective Study on the Effect of Ilaprazole in Non-erosive Reflux Disease Patients; Focused on Histologic Findings and Inflammatory Biomarker Completed NCT02666976 Phase 4 Ilaprazole
20 An Open-Label Trial of Dexlansoprazole 60mg for the Relief of Heartburn During the Fasting Month of Ramadan Completed NCT03079050 Phase 4 Dexlansoprazole 60 MG
21 Study to Assess Management Strategies for the Use of Esomeprazole (Nexium) in Helicobacter Pylori Infected Patients Completed NCT00574925 Phase 4 Esomeprazole
22 A Study of Rabeprazole and Pantoprazole on Stomach Acid and Esophageal Acid Exposure in Patients With Gastroesophageal Reflux Disease (GERD) and a History of Nighttime Heartburn Completed NCT00237367 Phase 4 rabeprazole and pantoprazole
23 Do Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux Predict Response to Treatment? Completed NCT00444145 Phase 4 Prevacid
24 Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD) Completed NCT00872755 Phase 4
25 Chemotherapy for Patients With Non-Small Cell Lung Cancer Completed NCT00380718 Phase 4 pemetrexed
26 Trimebutine Maleate Combined With Rabeprazole in Patients With Grade A or B Reflux Esophagitis Whose Symptoms Refractory to Rabeprazole Recruiting NCT02986685 Phase 4 Trimebutine Maleate;rabeprazole
27 Vonoprazan Study of Investigating the Effect on Sleep Disturbance Associated With Reflux Esophagitis- Exploratory Evaluation Recruiting NCT03116841 Phase 4 Vonoprazan
28 Prevention of Silent Cerebral Thromboembolism by Oral Anticoagulation With Dabigatran After Pulmonary Vein Isolation for Atrial Fibrillation Recruiting NCT02067182 Phase 4 Dabigatran
29 Vonoprazan Study in Patients With Erosive Esophagitis to Evaluate Long-term Safety Active, not recruiting NCT02679508 Phase 4 Vonoprazan;Lansoprazole
30 Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD) Active, not recruiting NCT01110811 Phase 4
31 Treatment Effect Between Dexlansoprazole and Double-dose Lansoprazole in Obesity Patients With Reflux Esophagitis Enrolling by invitation NCT02759393 Phase 4 Dexlansoprazole;Lansoprazole
32 The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump Inhibitors Terminated NCT01404832 Phase 4 Treat with lansoprazole 30 mg BID for 2 weeks, endoscopic examination with esophageal biopsy for patients with persistent symptoms
33 Lansoprazole Preventing Gastroduodenal Stress Ulcerations Terminated NCT00220909 Phase 4 Lansoprazole
34 Dexilant Treatment in Gastrointestinal Reflux Disease (GERD Related Non Cardiac Chest Pain Withdrawn NCT01637571 Phase 4 Dexilant;Dexilant Placebo
35 A Trial of Reconstruction After Distal Gastrectomy for Gastric Cancer Unknown status NCT01065688 Phase 3
36 Endoscopic Fundoplication Versus Proton Pump Inhibitors for GERD Treatment Unknown status NCT00857597 Phase 3 Proton Pump Inhibitors; active control
37 Reflux Esophagitis Phase III Study (Initial Treatment) Completed NCT00633932 Phase 3 Esomeprazole;Esomeprazole;Omeprazole
38 Reflux Esophagitis Phase III Study (Maintenance Treatment) Completed NCT00634114 Phase 3 Esomeprazole;Esomeprazole;Omeprazole
39 Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis Completed NCT00251719 Phase 3 Dexlansoprazole MR;Dexlansoprazole MR;Lansoprazole
40 Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis Completed NCT00251693 Phase 3 Dexlansoprazole MR;Dexlansoprazole MR;Lansoprazole
41 Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Erosive Esophagitis Completed NCT02456935 Phase 3 CJ-12420 100 mg QD;Esomeprazole 40 mg QD
42 Efficacy and Safety of Dexlansoprazole MR on Maintaining Healing in Subjects With Healed Erosive Esophagitis Completed NCT00255164 Phase 3 Dexlansoprazole MR;Dexlansoprazole MR;Placebo
43 Comparison of Dexlansoprazole MR to Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis Completed NCT00255151 Phase 3 Dexlansoprazole MR;Dexlansoprazole MR;Placebo
44 Efficacy and Safety of Dexlansoprazole MR Compared to Placebo on Maintaining Healing in Subjects With Healed Erosive Esophagitis Completed NCT00321737 Phase 3 Dexlansoprazole MR;Dexlansoprazole MR;Placebo
45 Study to Confirm the Safety and Efficacy of CJ-12420 in Patients With Erosive Esophagitis Completed NCT03006874 Phase 3 CJ-12420 100mg QD;Esomeprazole 40mg;CJ-12420 50mg QD
46 Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Erosive Esophagitis Completed NCT01452698 Phase 3 TAK-438;Placebo;Lansoprazole;Placebo
47 Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Maintenance Treatment of Healed Erosive Esophagitis Completed NCT01459367 Phase 3 TAK-438;TAK-438;Lansoprazole
48 Efficacy and Safety of Oral Once-Daily Vonoprazan (TAK-438) in Participants With Erosive Esophagitis Completed NCT02388724 Phase 3 Vonoprazan;Lansoprazole;Vonoprazan Placebo;Lansoprazole Placebo
49 A Multi-center, Randomized, Double-blind Phase III Clinical Trial to Assess and Compare to the Efficacy and Safety of Lafutidine, Famotidine and Omeprazole-referenced in Korean Erosive Esophagitis Patients Completed NCT01499368 Phase 3 Lafutidine;Famotidine;Omeprazole
50 Open-Label Extension Study of Reslizumab in Pediatric Subjects With Eosinophilic Esophagitis Completed NCT00635089 Phase 3 reslizumab

Search NIH Clinical Center for Esophagitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: esophagitis

Genetic Tests for Esophagitis

Genetic tests related to Esophagitis:

id Genetic test Affiliating Genes
1 Esophagitis 29

Anatomical Context for Esophagitis

MalaCards organs/tissues related to Esophagitis:

39
Lung, Lymph Node, Endothelial, Testes, Liver, Colon, Bone

Publications for Esophagitis

Articles related to Esophagitis:

(show top 50) (show all 8828)
id Title Authors Year
1
Vitamin D Signaling Pathways Confer the Susceptibility of Esophageal Squamous Cell Carcinoma in a Northern Chinese Population. ( 28362172 )
2017
2
A ligand-based and enediyne-energized bispecific fusion protein targeting epidermal growth factor receptor and insulin-like growth factor-1 receptor shows potent antitumor efficacy against esophageal cancer. ( 28498434 )
2017
3
Management of esophageal gastrointestinal stromal tumor: review of one hundred seven patients. ( 28881878 )
2017
4
Comparative evaluation of target volumes defined by deformable and rigid registration of diagnostic PET/CT to planning CT in primary esophageal cancer. ( 28072693 )
2017
5
Downregulation of esophageal cancer-related gene 4 promotes proliferation and migration of hepatocellular carcinoma. ( 28927132 )
2017
6
RICTOR expression in esophageal squamous cell carcinoma and its clinical significance. ( 28132115 )
2017
7
Peroral endoscopic myotomy for an achalasia patient with multiple esophageal diverticula. ( 27967203 )
2017
8
Intramural esophageal bronchogenic cyst mimicking achalasia in a toddler. ( 27822780 )
2017
9
Expression of hypoxia inducible factor 1 alpha and its clinical significance in esophageal carcinoma: A meta-analysis. ( 28671053 )
2017
10
Endosonographic features of esophageal tuberculosis presenting as a subepithelial lesion. ( 28139030 )
2017
11
Endoscopic submucosal dissection of a huge esophageal atypical lipomatous tumor (well-differentiated liposarcoma) with a 4-year recurrence-free survival. ( 28719927 )
2017
12
The effects of air pollution on mortality and clinicopathological features of esophageal cancer. ( 28489588 )
2017
13
Esophageal diverticulosis. ( 28747951 )
2017
14
P53 and SOX2 Protein Expression Predicts Esophageal Adenocarcinoma in Response to Neoadjuvant Chemoradiotherapy. ( 28059963 )
2017
15
DNA Methylation Status of PAX1 and ZNF582 in Esophageal Squamous Cell Carcinoma. ( 28241446 )
2017
16
Overexpressed PTOV1 associates with tumorigenesis and progression of esophageal squamous cell carcinoma. ( 28651486 )
2017
17
Effects of silenced PAR-2 on cell proliferation, invasion and metastasis of esophageal cancer. ( 28943918 )
2017
18
Future Directions in Improving Outcomes for Patients with Gastric and Esophageal Cancer. ( 28501093 )
2017
19
Esophageal Injury and Atrioesophageal Fistula Caused by Ablation for Atrial Fibrillation. ( 28947480 )
2017
20
Statin use after esophageal cancer diagnosis and survival: A population based cohort study. ( 28486205 )
2017
21
IL-6/STAT3/TWIST inhibition reverses ionizing radiation-induced EMT and radioresistance in esophageal squamous carcinoma. ( 28061440 )
2017
22
Downregulation of ST6GALNAC1 is associated with esophageal squamous cell carcinoma development. ( 28035351 )
2017
23
Endoscopic ultrasound in diagnosis of esophageal tuberculosis: 10-year experience at a tertiary care center. ( 28575247 )
2017
24
Gastrointestinal: Unusual endoscopic finding in a patient with dysphagia and gastro-esophageal reflux. ( 28948705 )
2017
25
Esophageal Cancer Diagnosed by Thyroid Scintigraphy. ( 28525453 )
2017
26
Intermittent pneumatic compression in combination with low-molecular weight heparin in the prevention of venous thromboembolic events in esophageal cancer surgery. ( 28054341 )
2017
27
Ulcerative Gastritis and Esophagitis in Two Children with Sarcina ventriculi Infection. ( 28913339 )
2017
28
Dosimetric comparison to the heart and cardiac substructure in a large cohort of esophageal cancer patients treated with proton beam therapy or Intensity-modulated radiation therapy. ( 28917586 )
2017
29
Lymphocytic esophagitis: A rare finding in adult patients with dysphagia and food impaction. ( 28089355 )
2017
30
Dosimetric predictors for acute esophagitis during radiation therapy for lung cancer: Results of a large statewide observational study. ( 28919249 )
2017
31
Esophageal squamous papillomas with focal dermal hypoplasia and eosinophilic esophagitis. ( 28405153 )
2017
32
Discrepancy Between Clinical and Pathologic Nodal Status of Esophageal Cancer and Impact on Prognosis and Therapeutic Strategy. ( 28948524 )
2017
33
Giant Esophageal Liposarcoma. ( 28840446 )
2017
34
Esophageal Atresia/Tracheoesophageal Fistula Repair Complicated by Tracheomalacia: A Case Report of Successful Management of Respiratory Distress Using Caudal Morphine. ( 28410264 )
2017
35
Esophageal chemical clearance and baseline impedance values in patients with chronic autoimmune atrophic gastritis and gastro-esophageal reflux disease. ( 28487082 )
2017
36
Review of surgical and anesthetic management for esophageal atresia with tracheoesophageal fistula, unilateral pulmonary agenesis and dextrocardia. ( 28417152 )
2017
37
Esophageal Cancer: Genomic and Molecular Characterization, Stem Cell Compartment and Clonal Evolution. ( 28930282 )
2017
38
Thoracoscopic Surgery in a Patient with Multiple Esophageal Carcinomas after Surgery for Esophageal Achalasia. ( 28951795 )
2017
39
Angiolipoma: a rare esophageal submucosal tumor. ( 28237393 )
2017
40
Folate intake, serum folate levels and esophageal cancer risk: an overall and dose-response meta-analysis. ( 28060731 )
2017
41
miR-202 Promotes Cell Apoptosis in Esophageal Squamous Cell Carcinoma by Targeting HSF2. ( 28277193 )
2017
42
Metabolic Perturbation and Potential Markers in Patients with Esophageal Cancer. ( 28512469 )
2017
43
Thoracic skeletal anomalies following surgical treatment of esophageal atresia. Lessons from a national cohort. ( 28778692 )
2017
44
ZEB1 induced miR-99b/let-7e/miR-125a cluster promotes invasion and metastasis in esophageal squamous cell carcinoma. ( 28408353 )
2017
45
The expression and significance of HOX transcript antisense RNA and epithelial-mesenchymal transition-related factors in esophageal squamous cell carcinoma. ( 28260072 )
2017
46
Solute Carrier Family 39 Member 6 Gene Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-Kinase Signaling, and Up-regulating Genes That RegulateA Metastasis. ( 28209530 )
2017
47
Vav1 expression is increased in esophageal squamous cell carcinoma and indicates poor prognosis. ( 28336434 )
2017
48
RESPONSE TO LETTER TO THE EDITOR: Boerhaave syndrome - case report. A case of acute necrotizing esophagitis Black esophagus: new insights and multicenter international experience in 2014. ( 28443952 )
2017
49
Original Research: miR-194 inhibits proliferation and invasion and promotes apoptosis by targeting KDM5B in esophageal squamous cell carcinoma cells. ( 27480251 )
2017
50
SQLE induces epithelial-to-mesenchymal transition by regulating of miR-133b in esophageal squamous cell carcinoma. ( 28069586 )
2017

Variations for Esophagitis

Expression for Esophagitis

Search GEO for disease gene expression data for Esophagitis.

Pathways for Esophagitis

Pathways related to Esophagitis according to GeneCards Suite gene sharing:

(show top 50) (show all 58)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
14.01 CCL11 CXCL8 DSG1 IL13 IL1B IL5
2
Show member pathways
13.82 CCL11 CCL26 CCR3 CXCL8 IL13 IL1B
3
Show member pathways
13.53 CCL11 CCL26 CXCL8 IL13 IL1B IL5
4
Show member pathways
13.41 CCL11 CCL26 CCR3 CXCL8 IL13 IL1B
5
Show member pathways
13.37 CCL11 CCL26 CCR3 CXCL8 IL13 IL1B
6
Show member pathways
13.35 CCL11 CXCL8 IL13 IL1B IL5 IL6
7
Show member pathways
13.27 CCL11 CCL26 CCR3 CXCL8 IL13 IL1B
8
Show member pathways
12.85 CCL11 CXCL8 IL13 IL1B IL5 IL6
9
Show member pathways
12.78 CXCL8 IL13 IL1B IL6 TP53
10 12.67 CXCL8 IL6 PTGS2 TGFB1 TP53
11
Show member pathways
12.59 IL13 IL1B IL5 IL6 TGFB1
12
Show member pathways
12.43 IL13 IL1B IL5 TP53
13
Show member pathways
12.41 IL1B IL5 IL6 TGFB1
14
Show member pathways
12.33 CCL11 CCL26 CCR3 CXCL8
15
Show member pathways
12.31 CCL11 CXCL8 IL13 IL1B IL5 IL6
16
Show member pathways
12.28 CXCL8 IL1B IL6 PTGS2 TP53
17
Show member pathways
12.21 IL13 IL5 IL6 TSLP
18
Show member pathways
12.18 CCL11 CXCL8 IL1B IL6
19 12.18 IL6 PTGS2 TGFB1 TP53
20 12.17 CXCL8 IL13 IL1B IL6
21
Show member pathways
12.17 CXCL8 IL13 IL1B IL5 IL6
22
Show member pathways
12.04 IL13 IL1B IL5 TP53
23
Show member pathways
12.03 CCL11 CCL26 CCR3 CXCL8
24 12.01 CXCL8 IL1B IL6 PTGS2 TGFB1 TP53
25 11.97 CCR3 IL5 IL6
26 11.96 SOD2 TGFB1 TP53
27 11.96 CXCL8 IL1B IL6 TGFB1 TP53
28 11.93 IL1B IL6 PTGS2
29 11.93 CXCL8 IL1B IL6 TGFB1
30
Show member pathways
11.92 IL1B IL6 TGFB1
31 11.91 CXCL8 IL1B IL6 TGFB1
32
Show member pathways
11.89 IL1B IL6 TGFB1
33 11.88 IL1B IL5 IL6
34 11.88 CXCL8 IL1B IL6 TGFB1
35 11.87 CXCL8 IL1B PTGS2
36
Show member pathways
11.85 CXCL8 IL6 TGFB1
37 11.82 CXCL8 IL1B IL6
38 11.82 CXCL8 IL13 IL5 IL6 TP53
39 11.81 IL13 IL1B IL5 TSLP
40
Show member pathways
11.75 CXCL8 IL5 PTGS2
41 11.75 CXCL8 IL1B IL6
42 11.75 IL1B IL6 TGFB1
43 11.71 IL5 IL6 TGFB1
44
Show member pathways
11.7 CXCL8 IL1B IL6 PTGS2
45 11.66 CCL11 CCL26 IL5
46 11.61 CCL11 CXCL8 IL13 IL1B IL6 PTGS2
47 11.6 CXCL8 IL1B IL6
48 11.6 CXCL8 IL6 PTGS2 TGFB1 TP53
49 11.57 CXCL8 IL1B IL6 TGFB1
50 11.57 CXCL8 IL13 IL1B IL6 PTGS2

GO Terms for Esophagitis

Cellular components related to Esophagitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 CCL11 CCL26 CXCL8 IL13 IL1B IL5
2 extracellular space GO:0005615 9.28 CCL11 CCL26 CXCL8 IL13 IL1B IL5

Biological processes related to Esophagitis according to GeneCards Suite gene sharing:

(show all 33)
id Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.96 IL6 PTGS2 SOD2 TGFB1
2 positive regulation of cell proliferation GO:0008284 9.92 IL5 IL6 PTGS2 TGFB1
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.9 CCL11 CCL26 IL6 TGFB1
4 aging GO:0007568 9.89 IL6 PTGS2 SOD2 TGFB1
5 chemotaxis GO:0006935 9.87 CCL11 CCL26 CCR3 CXCL8
6 cellular response to tumor necrosis factor GO:0071356 9.85 CCL11 CCL26 CXCL8 IL6
7 positive regulation of angiogenesis GO:0045766 9.84 CCL11 CCR3 CXCL8 IL1B
8 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.83 IL1B IL5 IL6
9 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.81 IL6 PTGS2 TGFB1
10 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.81 IL5 IL6 TGFB1 TP53
11 movement of cell or subcellular component GO:0006928 9.8 CXCL8 IL13 PTGS2
12 cellular response to mechanical stimulus GO:0071260 9.8 IL13 IL1B PTGS2 TGFB1
13 response to lipopolysaccharide GO:0032496 9.8 IL13 IL1B IL6 PTGS2 SOD2
14 positive regulation of endothelial cell proliferation GO:0001938 9.79 CCL11 CCL26 CCR3
15 positive regulation of smooth muscle cell proliferation GO:0048661 9.78 IL13 IL6 PTGS2
16 cellular response to interleukin-1 GO:0071347 9.78 CCL11 CCL26 CXCL8 IL6
17 positive regulation of cell migration GO:0030335 9.76 CCL11 CCL26 SOD2 TGFB1
18 negative regulation of fat cell differentiation GO:0045599 9.75 IL6 SOD2 TGFB1
19 monocyte chemotaxis GO:0002548 9.73 CCL11 CCL26 IL6
20 chemokine-mediated signaling pathway GO:0070098 9.73 CCL11 CCL26 CCR3 CXCL8
21 positive regulation of vascular endothelial growth factor production GO:0010575 9.7 IL1B PTGS2 TGFB1
22 negative regulation of cell proliferation GO:0008285 9.7 CXCL8 IL1B IL6 PTGS2 SOD2 TGFB1
23 neutrophil chemotaxis GO:0030593 9.67 CCL11 CCL26 CXCL8 IL1B
24 positive regulation of chemotaxis GO:0050921 9.65 CCL26 TGFB1
25 positive regulation of immunoglobulin secretion GO:0051024 9.64 IL5 IL6
26 positive regulation of histone deacetylation GO:0031065 9.64 TGFB1 TP53
27 response to manganese ion GO:0010042 9.62 PTGS2 SOD2
28 positive regulation of nitric oxide biosynthetic process GO:0045429 9.62 IL1B IL6 PTGS2 SOD2
29 positive regulation of fever generation GO:0031622 9.58 IL1B PTGS2
30 response to radiation GO:0009314 9.56 CCL11 PTGS2 SOD2 TGFB1
31 immune response GO:0006955 9.56 CCL11 CCL26 CXCL8 HRH2 IL13 IL1B
32 inflammatory response GO:0006954 9.32 CCL11 CCL26 CCR3 CXCL8 IL13 IL1B
33 positive regulation of transcription, DNA-templated GO:0045893 10.05 IL1B IL5 IL6 TGFB1 TP53

Molecular functions related to Esophagitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.55 CYP2C19 PTGS2 SOD2 TGFB1 TP53
2 chemokine activity GO:0008009 9.43 CCL11 CCL26 CXCL8
3 cytokine activity GO:0005125 9.28 CCL11 CCL26 CXCL8 IL13 IL1B IL5
4 CCR3 chemokine receptor binding GO:0031728 8.96 CCL11 CCL26

Sources for Esophagitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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