EOE
MCID: ESP035
MIFTS: 40

Esophagitis, Eosinophilic, 1 (EOE) malady

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Esophagitis, Eosinophilic, 1

About this section
Sources:
11Disease Ontology, 12diseasecard, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 32ICD9CM, 39MeSH, 40MESH via Orphanet, 45NCIt, 52OMIM, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Esophagitis, Eosinophilic, 1:

Name: Esophagitis, Eosinophilic, 1 52 12
Eosinophilic Esophagitis 11 54 39 13 68
 
Eoe 54

Characteristics:

Orphanet epidemiological data:

54
eosinophilic esophagitis:
Inheritance: Multigenic/multifactorial,Not applicable; Prevalence: 1-5/10000 (Canada),1-5/10000 (Japan),1-5/10000 (Spain),1-5/10000 (Europe),1-5/10000 (United States),1-9/100000 (Switzerland),1-5/10000 (Switzerland); Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

OMIM52 610247
Disease Ontology11 DOID:13922
ICD1030 K20.0
ICD9CM32 530.13
MeSH39 D057765
SNOMED-CT62 235599003
NCIt45 C27105
Orphanet54 ORPHA73247
ICD10 via Orphanet31 K20
MESH via Orphanet40 D057765
UMLS via Orphanet69 C0341106

Summaries for Esophagitis, Eosinophilic, 1

About this section
OMIM:52 Eosinophilic esophagitis (EOE) has an incidence of approximately 1 per 10,000 people. Symptoms include difficulty... (610247) more...

MalaCards based summary: Esophagitis, Eosinophilic, 1, also known as eosinophilic esophagitis, is related to eosinophilic enteropathy and esophagitis, and has symptoms including vomiting, epigastric pain and failure to thrive. An important gene associated with Esophagitis, Eosinophilic, 1 is EOE1 (Esophagitis, Eosinophilic), and among its related pathways are OX40 Pathway and Cytokines and Inflammatory Response. Affiliated tissues include esophagus, and related mouse phenotypes are respiratory system and hematopoietic system.

Disease Ontology:11 An esophagitis characterized by inflammation involving eosinophils located in esophagus.

Related Diseases for Esophagitis, Eosinophilic, 1

About this section

Diseases in the Esophagitis, Eosinophilic, 1 family:

Esophagitis, Eosinophilic, 2

Diseases related to Esophagitis, Eosinophilic, 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 121)
idRelated DiseaseScoreTop Affiliating Genes
1eosinophilic enteropathy11.1
2esophagitis10.9
3autosomal dominant intellectual disability 3010.9
4extraskeletal ewing sarcoma10.8
5dahlberg borer newcomer syndrome10.2IL13, IL5
6aortic atherosclerosis10.2IL13, IL5
7renal hypertension10.2IL13, IL5
8hypercementosis10.2IL13, IL5
9spastic paraplegia 3a, autosomal dominant10.2IL13, IL5
10peptidic growth factors deficiency10.2CCL11, IL5
11natural killer cell leukemia10.2CCL11, IL5
12exudative vitreoretinopathy 2, x-linked10.2IL13, IL5
13paracoccidioidomycosis10.2ATP4A, IER3IP1
14indian plum allergy10.2IL13, IL5
15gastroesophageal reflux10.2
16latent syphilis10.2CCL11, IL5
17luminal breast carcinoma10.2IL13, IL5
18necrotizing gastritis10.1CCL11, IL5
19lactose intolerance10.1IL13, IL5
20askin's tumor10.1IL13, IL5
21lacrimal apparatus disease10.1ATP4A, EPC2
22smooth muscle tumor10.1IL13, IL5
23cutaneous fibrous histiocytoma10.1CCL11, IL5
24astrocytoma10.1CCL26, IL5
25celiac disease10.1
26prostate small cell carcinoma10.1IL13, IL5
27food allergy10.1
28cerebral primitive neuroectodermal tumor10.1CCL11, IL5, TSLP
29apricot allergy10.1CCL11, IL5, TSLP
30thelaziasis10.1CCL11, IL13, IL5
31metal allergy10.1IL13, IL5
32lymphoblastic leukemia10.1CCL11, IL13, IL5
33spastic diplegia10.1CCL11, IL13, IL5
34dysphagia10.1
35visceral steatosis10.1CCL11, IL13, IL5
36intravascular angioleiomyoma10.1CCL11, IL13, IL5
37ethmoid sinusitis10.1CCL11, IL13, IL5
38childhood malignant mesenchymoma10.1CCL11, IL13, IL5
39inflamed seborrheic keratosis10.1CCL11, IL13, IL5
40hydrophthalmos10.1CCL11, IL13, IL5
41thyroid hyalinizing trabecular adenoma10.0CCL11, IL13, IL5
42acute dacryoadenitis10.0CCL11, IL13, IL5
43pulmonary tuberculosis10.0CCL11, IL13, IL5
44birth defects10.0CCL11, IL13, IL5
45bare lymphocyte syndrome, type i10.0CCL11, IL13, IL5
46malignant peritoneal solitary fibrous tumor10.0CCL11, IL13, IL5
47glucocorticoid resistance10.0CCL11, IL13, IL5
48rectum squamous cell carcinoma10.0CCL11, IL13, IL5
49duodenal somatostatinoma10.0IL13, IL5
50hypersensitivity vasculitis10.0IL5, STAT6

Graphical network of the top 20 diseases related to Esophagitis, Eosinophilic, 1:



Diseases related to esophagitis, eosinophilic, 1

Symptoms & Phenotypes for Esophagitis, Eosinophilic, 1

About this section

Symptoms by clinical synopsis from OMIM:

610247

Clinical features from OMIM:

610247

Human phenotypes related to Esophagitis, Eosinophilic, 1:

 64
id Description HPO Frequency HPO Source Accession
1 failure to thrive64 HP:0001508
2 vomiting64 HP:0002013
3 dysphagia64 HP:0002015
4 esophagitis64 HP:0100633

UMLS symptoms related to Esophagitis, Eosinophilic, 1:


vomiting, epigastric pain

MGI Mouse Phenotypes related to Esophagitis, Eosinophilic, 1 according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.1CCL11, IL13, IL5, STAT6, TSLP
2MP:00053978.0ATP4A, CCL11, IL13, IL5, POSTN, STAT6
3MP:00053878.0ATP4A, CCL11, IL13, IL5, POSTN, STAT6

Drugs & Therapeutics for Esophagitis, Eosinophilic, 1

About this section

Drugs for Esophagitis, Eosinophilic, 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 107)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
BudesonideapprovedPhase 4, Phase 3, Phase 243251333-22-363006, 5281004
Synonyms:
(11-beta,16-alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione
(11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione
(4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
(R,S)-11b,16a,17,21,tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with buty raldehyde
(RS)-(11beta,16alpha)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione
(RS)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde
(S)-16alpha,17-(Butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
11beta,21-dihydroxy-16alpha,17alpha-(butane-1,1-diyldioxy)pregna-1,4-diene-3,20-dione
16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione
16,17-Butylidenebis(oxy)-11-,21-dihydroxypregna-1,4-diene-3,20-dione
16-alpha,17-alpha-Butylidenedioxy-11-beta,21-dihydroxy-1,4-pregnadiene-3,20-dione
16alpha(R),17-(Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
16alpha-,17alpha--butylidenedioxypregna-1,4-diene-11beta-,21-diol-3,20-dione
51333-22-3
AC-4697
AC1L1DQE
AC1L1Y6Y
AC1L22VC
AC1MHWI7
B 7777
B7777_SIGMA
BPBio1_000523
BRD-A34299591-001-03-4
BRD-A82238138-001-01-7
BSPBio_000475
BSPBio_002160
Bidien
Bio-0010
Budecort Inhaler
Budenofalk
Budeson
Budesonide (JAN/USAN/INN)
Budesonide Easyhaler
Budesonide MMX
Budesonide [USAN:INN:BAN:JAN]
Budesonido
Budesonido [INN-Spanish]
Budesonidum
Budesonidum [INN-Latin]
Budiair
Budicort
C25H34O6
CCRIS 5230
CHEBI:3207
CHEBI:656601
CHEMBL1370
CID2462
CID3033890
CID40000
CID5281004
CID63006
CPD000058337
Cortivent
D00246
DB01222
Desowen
Dexbudesonide
Dexbudesonide [INN]
DivK1c_000475
EINECS 257-139-7
EINECS 257-160-1
EINECS 257-161-7
EU-0100174
Entocort
Entocort EC
Entocort EC (TN)
Giona Easyhaler
HMS1569H17
HMS1921I22
HMS2094I13
HMS501H17
Horacort
 
IDI1_000475
Inflammide
KBio1_000475
KBio3_001660
KBioGR_001361
LS-187734
LS-7235
Lopac0_000174
MAP-0010
MLS000028507
MLS001077323
MLS002207112
Micronyl
Miflonide
MolPort-002-529-265
MolPort-003-666-332
MolPort-003-986-909
NCGC00015165-03
NCGC00021318-03
NCGC00021318-06
NCGC00089747-02
NCGC00089747-03
NCGC00089747-04
NCGC00178789-01
NINDS_000475
Noex
Preferid
Pregna-1,4-diene-3,20-dione, 16,17-butylidenebis(oxy)-11,21-dihydroxy-, (11beta,16alpha(R))-, and 16alpha,17-((S)-Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
Prestwick0_000518
Prestwick1_000518
Prestwick2_000518
Prestwick3_000518
Prestwick_840
Pulmaxan
Pulmaxan turbohaler
Pulmicort
Pulmicort (TN)
Pulmicort Flexhaler
Pulmicort Nebuamp
Pulmicort Respules
Pulmicort Topinasal
Pulmicort Turbuhaler
Pulmicort turbuhaler
Respules
Rhinocort
Rhinocort Aqua
Rhinocort Turbuhaler
Rhinocort alpha
Rhinocort, Pulmicort , Entocort, Symbicort, Noex. Entocort EC, Budesonide
Rhinosol
S 1320
S-1320
S1286_Selleck
SAM002699898
SMR000058337
SPBio_000586
SPBio_002396
SPECTRUM1500813
ST51039033
Spectrum2_000623
Spectrum3_000620
Spectrum4_000821
Spectrum5_001738
Spirocort
TL8003397
Tridesilon
UDB
UNII-168L5HT37P
UNII-2HI1006KPH
UNII-Q3OKS62Q6X
Unit dose budesonide
ZINC03938751
ZINC04097286
budesonide
2
Lansoprazoleapproved, investigationalPhase 4, Phase 2, Phase 1218103577-45-33883
Synonyms:
103577-45-3
2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole
2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)benzimidazole
2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)-1H-benzimidazole
2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole
2-[({3-methyl-4-[(2,2,2-trifluoroethyl)oxy]pyridin-2-yl}methyl)sulfinyl]-1H-benzimidazole
2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole
2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl] methyl] sulfinyl] benzimidazole
2-[[[3-methyl-4-(2,2,2-trifluroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole
A 65006
A-65006
AB00052388
ABT-006
AC1L1GX8
AG 1749
AG-1749
Abbot Brand of Lansoprazole
Agopton
Almirall Brand of Lansoprazole
Amarin
Aprazol
BIDD:GT0006
BPBio1_001194
BRD-A49172652-001-05-7
BRN 4333393
BSPBio_001084
BSPBio_001830
Bamalite
Bio-0824
Biuret
Biuret Gr
Biuret Reagent
Biuret Reagent Solution
Blason
C058687
C16H14F3N3O2S
CAS-103577-45-3
CG-4801
CHEBI:6375
CHEMBL480
CID3883
CPD000058469
Compraz
D00355
DB00448
Dakar
DivK1c_000920
EU-0100709
FT-0082011
HMS1571G06
HMS1922M04
HMS2052F05
HMS2093M07
HMS502N22
HSDB 7204
Hoechst Brand of Lansoprazole
Hormona Brand of Lansoprazole
I06-0018
IDI1_000920
Ilsatec
KBio1_000920
KBio2_002060
KBio2_004628
KBio2_007196
KBio3_001330
KBioGR_001491
KBioSS_002060
Ketian
L 8533
L8533_SIGMA
LS-33080
Lancid
Lanfast
Lanproton
Lansopep
Lansophed
Lansoprazol
Lansoprazol [INN-Spanish]
Lansoprazole
Lansoprazole (JAN/USP/INN)
Lansoprazole [USAN:BAN:INN]
Lansoprazole [Usan:Ban:Inn]
Lansoprazolum
Lansoprazolum [INN-Latin]
Lansox
Lanston
 
Lanz
Lanzo
Lanzol
Lanzol-30
Lanzopral
Lanzor
Lanzul
Lapraz
Lasoprol
Lederle Brand of Lansoprazole
Limpidex
Linamarin
Lopac-L-8533
Lopac0_000709
MLS-0003247.0001
MLS000069705
MLS000759405
MLS001074170
Mesactol
MolPort-003-666-508
MolPort-006-394-760
Monolitum
NCGC00015615-01
NCGC00015615-02
NCGC00015615-03
NCGC00015615-06
NCGC00015615-11
NCGC00023826-03
NCGC00023826-04
NCGC00023826-05
NCGC00023826-06
NCGC00023826-07
NINDS_000920
Ogast
Ogastro
Opiren
Prestwick0_001072
Prestwick1_001072
Prestwick2_001072
Prestwick3_001072
PrevOnco
Prevacid
Prevacid (TN)
Prevacid I.V
Prevacid I.V.
Prevacid Iv
Prevacid SoluTab
Prevacid Solutab
Prevacid, Prevacid NapraPAC, Prevacid SoluTab, Lansoprazole
Prevpac
Prezal
Pro Ulco
Promeco
Promeco Brand of Lansoprazole
Promp
Prosogan
S1354_Selleck
SAM001246544
SMR000058469
SPBio_000488
SPBio_002992
SPECTRUM1503926
STK621169
Salvar Brand of Lansoprazole
Spectrum2_000444
Spectrum3_000295
Spectrum4_000856
Spectrum5_001521
Spectrum_001580
Suprecid
TAK 390MR
TAK-390MR
TAK390MR
TAP Brand of Lansoprazole
TL8000155
Takeda Brand of Lansoprazole
Takepron
Tecnobio Brand of Lansoprazole
UNII-0K5C5T2QPG
Ulpax
Vinas Brand of Lansoprazole
Wyeth Brand of Lansoprazole
Zoprol
Zoton
lansoprazole
lansoprazole sulphone
lanzoprazole
3
MentholapprovedPhase 426062216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
4Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 113180
5HormonesPhase 4, Phase 3, Phase 2, Phase 114415
6Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 113168
7Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 223689
8Anti-Asthmatic AgentsPhase 4, Phase 3, Phase 2, Phase 13488
9
FluticasonePhase 4, Phase 3, Phase 264490566-53-3, 80474-14-262924, 22833648
Synonyms:
90566-53-3
AC-456
AC1NSJZT
Asmatil
Axotide
BIDD:GT0819
Brethal
C07815
CHEMBL1201396
CID5311101
Cultivate
Cutivate
D07981
Flixonase
Flixonase Nasal Spray
Flixotide
Flixotide Disk
 
Flixotide Disks
Flixotide Inhaler
Flonase
Flovent
Flovent Diskus
Flovent Rotadisk
Fluinol
Flunase
Flusonal
Fluspiral
Fluticaps
Fluticaps (TN)
Fluticasone (INN)
Fluticasonpropionat Allen
Flutide
Flutivate
MolPort-006-666-449
S-(fluoromethyl) (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carbothioate
fluticasone
10glucocorticoidsPhase 4, Phase 3, Phase 2, Phase 15103
11Dermatologic AgentsPhase 4, Phase 3, Phase 25806
12Cromolyn SodiumPhase 417
13Anti-Allergic AgentsPhase 4, Phase 3, Phase 2, Phase 11522
14Respiratory System AgentsPhase 4, Phase 3, Phase 2, Phase 14997
15Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 2, Phase 110729
16Bronchodilator AgentsPhase 4, Phase 3, Phase 22965
17Autonomic AgentsPhase 4, Phase 3, Phase 210150
18Gastrointestinal AgentsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 18402
19
DexlansoprazolePhase 4, Phase 2, Phase 1218138530-94-6, 103577-45-39578005
Synonyms:
138530-94-6
CHEMBL1201863
CID9578005
D08903
Dexlansoprazole (INN/USAN)
KS-1075
 
Kapidex
MolPort-002-885-834
T 168390
TAK 390
UNII-UYE4T5I70X
ZINC00599734
dexlansoprazole
20AntacidsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 11842
21
Proton pump inhibitorsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 11123
Synonyms:
 
PPIs
22Anti-Ulcer AgentsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 11842
23Soy BeanNutraceuticalPhase 4, Phase 2, Phase 3, Early Phase 1554
24OliveNutraceuticalPhase 4278
25
MontelukastapprovedPhase 3, Phase 1270158966-92-85281040
Synonyms:
(R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
(R-(e))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
1-((((1R)-1-(3-((1E)-2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
1-[[[(1 R)-1-[3-[(1e)-2-(7-chloro-2-Quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid
151767-02-1 (sodium)
158966-92-8
2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
AC1NQXXW
Apxi toxin
BIDD:GT0394
Brondilat
Brondilat (TN)
C07482
C35H36ClNO3S
CHEBI:50730
CHEMBL787
CID5281040
 
D08229
DB00471
HMS2089D07
HSDB 7582
LS-173539
MK 0476
MK-0476
Montair
Montelukast
Montelukast (INN)
Montelukast [INN:BAN]
Montelukastum
Montélukast
Singulair
Singular
UNII-MHM278SD3E
montelukast
sodium 1-(((1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropylacetate
{1-[({(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetic acid
26
Esomeprazoleapproved, investigationalPhase 2, Phase 3333161796-78-7, 119141-88-74594, 9579578
Synonyms:
( -)-Omeprazole
(-)-Omeprazole
(-)-omeprazole
(S)-(-)-Omeprazole
(S)-(−)-omeprazole
(S)-Omeprazole
(S)-omeprazole
(s)-omeprazole
(−)-omeprazole
119141-88-7
119141-89-8
131959-78-9
172964-80-6
193469-77-1
2-(((3,5-Dimethyl-4-methoxy-2-pyridyl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole
2-({[3,5-dimethyl-4-(methyloxy)pyridin-2-yl]methyl}sulfinyl)-5-(methyloxy)-1H-benzimidazole
326602-80-6
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole
5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1-methyl-1H-benzimidazole
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
73590-58-6
AC-401
AC1L1IIJ
AGI-010
AKOS005066653
AULCER
Antra
Antra MUPS
Audazol
Axagon
BIDD:GT0020
BIDD:GT0189
BPBio1_000425
BRD-A55962179-001-04-9
BSPBio_000385
Belmazol
Bio-0888
C07324
CAS-73590-58-6
CCRIS 7099
CHEBI:50275
CHEBI:519601
CHEBI:7772
CHEMBL1503
CID4594
CID9568614
CID9579578
CPD000058847
Ceprandal
D00455
D07917
DB00338
DB00736
DM-3458
Danlox
Demeprazol
Desec
Dizprazol
Dudencer
Elgam
Emeproton
Emilok
Epirazole
Erbolin
Esomeprazol
Esomeprazole
Esomeprazole (INN)
Esomeprazole Sodium
Esomeprazole [INN:BAN]
Esomeprazolum
Esomperazole
Esopral
Exter
Gasec
Gastrimut
Gastroloc
Gibancer
H 168-68
H 168/68
H-168/68
H168/68
HMS1528I05
HMS1569D07
HMS2052G17
HMS2090E16
HMS2090F11
HSDB 3575
I06-0705
IDI1_032523
InChI=1/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20
Indurgan
Inexium paranova
Inexium paranova (TN)
Inhibitron
Inhipump
LS-185188
LS-7629
Lensor
Logastric
Lomac
Losec
Losec, Omesec, Prilosec, Zegerid, Omeprazole
Lucen
MLS000069373
MLS001076112
MLS001424148
Maybridge4_002645
Mepral
 
Miol
Miracid
MolPort-003-666-741
MolPort-003-807-515
MolPort-003-849-702
MolPort-005-943-880
Mopral
Morecon
NCGC00016925-01
NCGC00016925-02
NCGC00021522-03
NCGC00021522-04
NCGC00021522-05
Nexiam
Nexium
Nexium Control
Nexium IV
Nilsec
Nopramin
Nuclosina
O0359
O104_SIGMA
OMEP
OMZ
Ocid
Olexin
Olit
Omapren
Omebeta
Omebeta 20
Omed
Omegast
Omepradex
Omepral
Omeprazol
Omeprazol [INN-Spanish]
Omeprazole (JAN/USP/INN)
Omeprazole S-form
Omeprazole [USAN:INN:BAN:JAN]
Omeprazole delayed-release
Omeprazole magnesium
Omeprazolum
Omeprazolum [INN-Latin]
Omeprazon
Omeprazone
Omeprol
Omesek
Omez
Omezol
Omezolan
Omid
Omisec
Omizac
Ompanyt
Ortanol
Osiren
Ozoken
Paprazol
Parizac
Pepticum
Pepticus
Peptilcer
Perprazole
Prazentol
Prazidec
Prazolit
Prestwick0_000493
Prestwick1_000493
Prestwick2_000493
Prestwick3_000493
Prestwick_808
Prilosec
Prilosec (TN)
Prilosec OTC
Procelac
Proclor
Prysma
Ramezol
Regulacid
Result
S1389_Selleck
SAM001246900
SAN-15
SMR000058847
SPBio_002306
STK623746
Sanamidol
Secrepina
TL8005099
Tedec Ulceral
UNII-KG60484QX9
UNII-N3PA6559FT
UPCMLD-DP075
UPCMLD-DP075:001
Ulceral
Ulcesep
Ulcometion
Ulcozol
Ulcsep
Ulsen
Ultop
Ulzol
Victrix
ZINC04693574
ZINC04693575
Zefxon
Zegerid
Zepral
Zimor
Zoltum
esomeprazol
esomeprazole
esomeprazolum
omeprazole
Ésoméprazole
27Leukotriene AntagonistsPhase 3, Phase 1293
28
InfliximabapprovedPhase 2392170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
29
Omalizumabapproved, investigationalPhase 2, Phase 1145242138-07-4
Synonyms:
242138-07-4
D05251
Ig gamma-1 chain C region
Omalizumab
 
Omalizumab (USAN/INN)
Omalizumab (genetical recombination)
Omalizumab (genetical recombination) (JAN)
Xolair
Xolair (TN)
30
LosartanapprovedPhase 2286114798-26-43961
Synonyms:
(2-Butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol
114798-26-4
124750-99-8 (mono-potassium salt)
1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
2-Butyl-4-chloro-1-((2'-(1H-etrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-methanol
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl-1H-imidazole-5-methanol
2-N-Butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole
2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5ylphenyl)benzyl]imidazole-5-methanol
2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole
2-n-butyl-4-chloro-5-hydroxymethyl-1-[[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl]methyl]imidazole
AC1L1H3Q
BIDD:GT0286
BRD-K76205745-001-02-5
BSPBio_002695
C07072
C22H23ClN6O
CHEBI:6541
CHEMBL191
CID3961
CL23623
Cozaar
D08146
DB00678
DUP 89
DuP 89
DuP-753
HMS1922J13
HMS2093E22
Hyzaar
I14-9710
Jsp001094
KBio2_002193
 
KBio2_004761
KBio2_007329
KBio3_001915
KBioGR_001611
KBioSS_002193
L000351
LOSARTAN POTASSIUM
LS-78746
Lacidipine
Lortaan
Losartan
Losartan (INN)
Losartan Potassium
Losartan [INN:BAN]
Losartan monopotassium salt
Losartic
Losartic (TN)
MK-954
MK954
MolPort-003-666-553
NCGC00095125-01
NCGC00095125-02
NCGC00095125-03
Oprea1_644635
SPBio_001893
SPECTRUM1504268
Spectrum2_001677
Spectrum3_000998
Spectrum4_001126
Spectrum5_001466
Spectrum_001713
UNII-JMS50MPO89
[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
losartan
losartan potassium
31
BethanecholapprovedPhase 24674-38-42370
Synonyms:
(2-Hydroxypropyl)trimethylammonium carbamate
1-Propanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl- (9CI)
2-((Aminocarbonyl)oxy)-N,N,N-trimethyl-1-propanaminium
2-(Carbamoyloxy)-N,N,N-trimethylpropan-1-aminium
2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium
2-Carbamoyloxypropyl-trimethylazanium
2-carbamoyloxypropyl(trimethyl)azanium
2-carbamoyloxypropyl-trimethylazanium
590-63-6 (chloride)
674-38-4
AB00053794
AC1L1DJ2
Amidopropyldimethylbetaine
Ammonium, (2-hydroxypropyl)trimethyl-, carbamate (ester)
BPBio1_001196
BRN 1773706
BSPBio_001086
BSPBio_001902
BTC
Besacholine
Bethaine Choline Chloride
Bethanechol
Bethanechol Chloride
Bethanecol
C06850
C7H17N2O2
CHEBI:3084
CHEMBL1482
CID2370
Carbamoyl-beta-methylcholine
Carbamyl-beta-methylcholine
Carbamylmethylcholine Chloride
DB01019
 
DivK1c_000179
HMS2089I08
IDI1_000179
KBio1_000179
KBio2_000504
KBio2_003072
KBio2_005640
KBio3_001402
KBioGR_000690
KBioSS_000504
LS-18498
Lopac0_000304
Myotonine chloride
NCGC00015245-06
NCGC00089770-02
NCGC00163217-01
NINDS_000179
Prestwick0_001073
Prestwick1_001073
Prestwick2_001073
Prestwick3_001073
SPBio_000204
SPBio_002993
Spectrum2_000132
Spectrum3_000311
Spectrum4_000255
Spectrum5_000892
Spectrum_000084
UNII-004F72P8F4
Urabeth
beta-Methyl Carbachol Chloride
bethanechol
carbamoyl-β-methylcholine
carbamyl-β-methylcholine
32Neurotransmitter AgentsPhase 218340
33interferonsPhase 1, Phase 22175
34Pharmaceutical SolutionsPhase 28192
35Indoleacetic AcidsPhase 212
36AntibodiesPhase 2, Phase 16394
37Antirheumatic AgentsPhase 210956
38ImmunoglobulinsPhase 2, Phase 16394
39Antibodies, MonoclonalPhase 2, Phase 14039
40Anti-Arrhythmia AgentsPhase 23093
41Angiotensin II Type 1 Receptor BlockersPhase 21091
42
Angiotensin IIPhase 2117868521-88-0, 11128-99-765143, 172198
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
43Angiotensin Receptor AntagonistsPhase 21191
44Antihypertensive AgentsPhase 24207
45AngiotensinogenPhase 21177
46Vasoconstrictor AgentsPhase 22122
47mometasone furoatePhase 217883919-23-7
48Cholinergic AgentsPhase 23992
49
Mannitolapproved, investigationalPhase 128069-65-8453, 6251
Synonyms:
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
(L)-Mannitol
1,2,3,4,5,6-Hexanehexol
123897-58-5
133-43-7
15719_ALDRICH
15719_RIEDEL
33440_RIEDEL
33440_SIGMA
36413-61-3
4-01-00-02841 (Beilstein Handbook Reference)
5149-40-6
63559_FLUKA
63559_SIGMA
63560_FLUKA
63565_FLUKA
63565_SIGMA
69-65-8
75398-80-0
85085-15-0
87-78-5
AB1002081
AC-12776
AC1L1M49
AC1Q28E5
AI3-19511
AR-1J3861
Ambap69-65-8
BRN 1721898
C00392
C6H14O6
CCRIS 369
CHEBI:16899
CHEMBL689
CID6251
Cordycepate
Cordycepic acid
D-(-)-Mannitol
D-Mannitol
D-Mannitol (JP15)
D-mannite
D-mannitol
D00062
D008353
DL-Mannitol
Diosmol
ED1D1E61-FEFB-430A-AFDC-D1F4A957FC3D
EINECS 200-711-8
EINECS 201-770-2
Fraxinine
HSDB 714
Hexahydroxyhexane
Hexanhexol
Invenex
Isotol
LS-1588
LS-89250
M0044
M1902_SIGMA
M4125_SIAL
M8429_SIAL
M9546_SIAL
M9647_SIAL
MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER
MANNITOL 15% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.45%
 
MANNITOL 25%
MANNITOL 5% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.12%
MLS001335977
MLS001335978
MTL
Manicol
Manitol
Maniton S
Maniton-S
Manna Sugar
Manna sugar
Mannazucker
Mannidex
Mannidex 16700
Mannigen
Mannistol
Mannit
Mannit p
Mannite
Mannitol
Mannitol (USP)
Mannitol (VAN)
Mannitol 10%
Mannitol 10% In Plastic Container
Mannitol 15%
Mannitol 15% In Plastic Container
Mannitol 20%
Mannitol 20% In Plastic Container
Mannitol 5%
Mannitol 5% In Plastic Container
Mannitol [USAN]
Mannitolum
Mannogem 2080
Marine Crystal
Marine crystal
MolPort-003-927-039
Mushroom sugar
NCGC00164246-01
NCI-C50362
NSC 407017
NSC 9256
OSMITROL 10% IN WATER IN PLASTIC CONTAINER
OSMITROL 15% IN WATER IN PLASTIC CONTAINER
OSMITROL 20% IN WATER IN PLASTIC CONTAINER
OSMITROL 5% IN WATER IN PLASTIC CONTAINER
Osmitrol
Osmitrol (TN)
Osmitrol 10% In Water
Osmitrol 15% In Water
Osmitrol 20% In Water
Osmitrol 5% In Water
Osmofundin
Osmosal
Resectisol
Resectisol In Plastic Container
SDM No. 35
SMR000857324
SORBITOL-MANNITOL IN PLASTIC CONTAINER
Sorbitol-Mannitol
TL806434
UNII-3OWL53L36A
ZINC02041302
bmse000099
cpd without stereochemical designation
e 421
e-421
e421
manita
mannitol
50
LactuloseapprovedPhase 11014618-18-211333
Synonyms:
(2S,3R,4S,5R,6R)-2-[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
4-O-b-D-Galactopyranosyl-D-Fructofuranose
4-O-b-D-Galactopyranosyl-D-fructose
4-O-beta-D-Galactopyranosyl-D-Fructofuranose
4-O-beta-D-Galactopyranosyl-D-fructofuranose
4-O-beta-D-Galactopyranosyl-D-fructose
4-O-beta-delta-Galactopyranosyl-delta-Fructofuranose
4-O-beta-delta-Galactopyranosyl-delta-fructose
 
Bifiteral
Cephulac
D-Lactulose
Lactulosa
Lactulose
Lactulosum
delta-Lactulose
lactulosa
lactulosum

Interventional clinical trials:

(show top 50)    (show all 112)
idNameStatusNCT IDPhase
1Oral Cromolyn Sodium for the Treatment of Eosinophilic EsophagitisUnknown statusNCT02371941Phase 4
2Dietetic Versus Topical Steroids for Pediatric Eosinophilic EsophagitisUnknown statusNCT01846962Phase 4
3The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump InhibitorsTerminatedNCT01404832Phase 4
4Open-Label Extension Study of Reslizumab in Pediatric Subjects With Eosinophilic EsophagitisCompletedNCT00635089Phase 3
5Efficacy and Safety Study of Reslizumab to Treat Eosinophilic Esophagitis in Subjects Aged 5 to 18 YearsCompletedNCT00538434Phase 2, Phase 3
6Budesonide Orodispersible Tablet vs. Placebo in Active Eosinophilic EsophagitisCompletedNCT02434029Phase 3
7A Study Comparing Swallowed Flovent and Placebo in Patients With Eosinophilic DisordersCompletedNCT00266578Phase 3
8The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic EsophagitisCompletedNCT00728481Phase 2, Phase 3
9Maintenance of Remission With Budesonide Orodispersible Tablets vs. Placebo in Eosinophilic EsophagitisRecruitingNCT02493335Phase 3
10A Placebo- Controlled Study in Adolescents and Adults With Eosinophilic Esophagitis (EoE) Measuring Histologic Response and Determine if Reduction in Dysphagia is AchievedRecruitingNCT02605837Phase 3
11An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE)RecruitingNCT02736409Phase 3
12Eosinophilic Esophagitis (EoE) Intervention Trial-Randomized 1 Food Elimination vs. 4 Food Elimination Diet Followed by Swallowed GlucocorticoidsRecruitingNCT02610816Phase 2, Phase 3
13SOFEED: Six Food vs. One Food Eosinophilic Esophagitis Diet StudyRecruitingNCT02778867Phase 2, Phase 3
14Eosinophilic Esophagitis Treatment: Montelukast vs FluticasoneActive, not recruitingNCT01702701Phase 3
15Safety and Efficacy of Three Doses of Oral Fluticasone Propionate in Adults With Eosinophilic EsophagitisNot yet recruitingNCT02873468Phase 2, Phase 3
16A Study of Flovent in Patients With Eosinophilic EsophagitisCompletedNCT00426283Phase 2
17Budesonide for Eosinophilic EsophagitisCompletedNCT00271349Phase 2
18Dose-Ranging Study of Oral Viscous Budesonide in Pediatrics With Eosinophilic EsophagitisCompletedNCT00762073Phase 2
19Topical Steroid Treatment for Eosinophilic EsophagitisCompletedNCT00275561Phase 2
20Use of Topical Budesonide in the Treatment of Eosinophilic EsophagitisCompletedNCT00638456Phase 2
21Proof of Concept Study of OC000459 in Eosinophilic EsophagitisCompletedNCT01056783Phase 2
22Dose Ranging Study of RPC4046 in Eosinophilic EsophagitisCompletedNCT02098473Phase 2
23Budesonide Effervescent Tablets vs. Viscous Budesonide Suspension vs. Placebo in Eosinophilic EsophagitisCompletedNCT02280616Phase 2
24Safety and Tolerability Study of Oral EUR-1100 to Treat Eosinophilic EsophagitisCompletedNCT01386112Phase 1, Phase 2
25Efficacy and Safety of QAX576 in Patients With Eosinophilic EsophagitisCompletedNCT01022970Phase 2
26A Pilot Study of the Treatment of Eosinophilic Esophagitis With OmalizumabCompletedNCT00123630Phase 2
27Comparison of Esomeprazole to Aerosolized, Swallowed Fluticasone for Eosinophilic EsophagitisCompletedNCT00123656Phase 2
28Off Label Use of Infliximab in Adult Patients With Severe Eosinophilic EsophagitisCompletedNCT00523354Phase 2
29OBS in Adolescent and Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an Open Label ExtensionCompletedNCT01642212Phase 2
30Intravenous Mepolizumab In Children With Eosinophilic EsophagitisCompletedNCT00358449Phase 2
31An Evaluation Of Mepolizumab In Therapy Of Eosinophilic Oesophagitis In Adult PatientsCompletedNCT00274703Phase 2
32Omalizumab to Treat Eosinophilic GastroenteritisCompletedNCT00084097Phase 2
33Anti-Interleukin-5 Antibody to Treat Hypereosinophilic SyndromeCompletedNCT00017862Phase 2
34Anti-Interleukin-5 (IL-5) Study for Hypereosinophilic SyndromeCompletedNCT00266565Phase 1, Phase 2
35Eosinophilic Esophagitis Clinical Therapy Comparison TrialRecruitingNCT01821898Phase 2
36An Open-Label Trial of Losartan Potassium in Participants With Eosinophilic Esophagitis (EoE)RecruitingNCT03029091Phase 2
37Milk Patch for Eosinophilic EsophagitisActive, not recruitingNCT02579876Phase 2
38Study of Dupilumab in Adult Patients With Active Eosinophilic Esophagitis (EoE)Active, not recruitingNCT02379052Phase 2
39Testing Effectiveness of Losartan in Patients With EoE With or Without a CTDActive, not recruitingNCT01808196Phase 2
40Mometasone-furoate for Treatment of Eosinophilic Esophagitis - a Randomized Placebo Controlled Study.Enrolling by invitationNCT02113267Phase 2
41Bethanechol for Eosinophilic EsophagitisTerminatedNCT02058537Phase 2
42Predictors of Proton Pump Inhibitor (PPI) Response in Eosinophilic EsophagitisWithdrawnNCT01479231Phase 1, Phase 2
43Evaluation of the Safety and Effectiveness of Tailored Transoral Incisionless Fundoplication (TIF) Using EsophyX for the Treatment of GERDWithdrawnNCT01025739Phase 2
44Observational Field Study of Acute Esophageal Food Bolus Impaction by Mean Esophageal Manometry and 24h-pH-monitoringUnknown statusNCT01447823Phase 1
45Intestinal Permeability in Response to Treatment in Eosinophilic Esophagitis PatientsCompletedNCT01641913Phase 1
46Identifying Responders to Xolair (Omalizumab) Using Eosinophilic Esophagitis as a Disease ModelCompletedNCT01040598Phase 1
47Trial of Montelukast in Eosinophilic EsophagitisCompletedNCT00511316Phase 1
48A Randomized Double Blind Placebo Controlled Study of the Effect of Swallowed Beclomethasone Dipropionate on Inflammatory Markers in Adult Patients With Eosinophilic EsophagitisCompletedNCT01016223Phase 1
49Study to Identify Non-Invasive Markers of Gastrointestinal AllergyCompletedNCT00272818Phase 1
50Using Spectrally Encoded Confocal Microscopy (SECM) to Image the EsophagusRecruitingNCT02202590Phase 1

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Cochrane evidence based reviews: eosinophilic esophagitis

Genetic Tests for Esophagitis, Eosinophilic, 1

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Anatomical Context for Esophagitis, Eosinophilic, 1

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FMA organs/tissues related to Esophagitis, Eosinophilic, 1:

17
Esophagus

Publications for Esophagitis, Eosinophilic, 1

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Variations for Esophagitis, Eosinophilic, 1

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Expression for genes affiliated with Esophagitis, Eosinophilic, 1

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Search GEO for disease gene expression data for Esophagitis, Eosinophilic, 1.

Pathways for genes affiliated with Esophagitis, Eosinophilic, 1

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GO Terms for genes affiliated with Esophagitis, Eosinophilic, 1

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Cellular components related to Esophagitis, Eosinophilic, 1 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056157.7ATP4A, CCL11, CCL26, IL13, IL5, POSTN

Biological processes related to Esophagitis, Eosinophilic, 1 according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1lymphocyte chemotaxisGO:004824710.3CCL11, CCL26
2monocyte chemotaxisGO:000254810.2CCL11, CCL26
3positive regulation of actin filament polymerizationGO:003083810.2CCL11, CCL26
4positive regulation of B cell proliferationGO:003089010.1IL13, IL5
5cellular response to tumor necrosis factorGO:00713569.9CCL11, CCL26, POSTN
6positive regulation of receptor activityGO:20002739.7CCL11, CCL26
7immune responseGO:00069559.6CCL11, CCL26, IL13, IL5
8inflammatory responseGO:00069549.5CCL11, CCL26, IL13, IL5

Molecular functions related to Esophagitis, Eosinophilic, 1 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1CCR chemokine receptor bindingGO:004802010.3CCL11, CCL26
2CCR3 chemokine receptor bindingGO:003172810.3CCL11, CCL26
3chemokine activityGO:000800910.3CCL11, CCL26
4receptor agonist activityGO:00480189.7CCL11, CCL26
5cytokine activityGO:00051258.9CCL11, CCL26, IL13, IL5, TSLP

Sources for Esophagitis, Eosinophilic, 1

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet