Essential Tremor malady
Categories: Genetic diseases, Rare diseases, Neuronal diseases
Aliases & Descriptions for Essential Tremor:
Global: Genetic diseases, Rare diseases
Anatomical: Neuronal diseases
NIH Rare Diseases:46 Essential tremor is the most common movement disorder. it is characterized by involuntary and rhythmic shaking (tremor), especially in the hands, without any other signs or symptoms. it is distinguished from tremor that results from other disorders or known causes, such as tremors seen with parkinson disease or head trauma. most cases of essential tremor are hereditary. there are five forms of essential tremor that are based on different genetic causes. several genes as well as lifestyle and environmental factors likely play a role in a person's risk of developing this complex condition. in mild cases, treatment may not be necessary. in cases where symptoms interfere with daily living, medications may help to relieve symptoms. last updated: 9/12/2014
MalaCards based summary: Essential Tremor, also known as benign essential tremor, is related to hereditary essential tremor 5 and sensorineural hearing loss-early graying-essential tremor syndrome, and has symptoms including essential and other specified forms of tremor, essential and other specified forms of tremor and myoclonus. An important gene associated with Essential Tremor is DRD3 (Dopamine Receptor D3), and among its related pathways are Alpha-synuclein signaling and Parkinsons Disease Pathway. The drugs propranolol and propranolol hydrochloride have been mentioned in the context of this disorder. Affiliated tissues include brain, cerebellum and cortex.
Disease Ontology:11 A movement disorder that causes involuntary tremors, especially in the hands. it occurs alone without other neurological signs and symptoms.
Genetics Home Reference:24 Essential tremor is a movement disorder that causes involuntary, rhythmic shaking (tremor), especially in the hands. It is distinguished from tremor that results from other disorders or known causes, such as Parkinson disease or head trauma. Essential tremor usually occurs alone, without other neurological signs or symptoms. However, some experts think that essential tremor can include additional features, such as mild balance problems.
OMIM:50 Essential tremor may be the most common human movement disorder. The main feature of essential tremor is postural... (190300) more...
NINDS:47 Tremor is an unintentional, somewhat rhythmic, muscle movement involving to-and-fro movements (oscillations) of one or more parts of the body. Essential tremor (previously called benign essential tremor) is the most common form of abnormal tremor. (In some people, tremor is a symptom of a neurological disorder or appears as a side effect of certain drugs.)
UniProtKB/Swiss-Prot:68 Tremor, hereditary essential 1: A common movement disorder mainly characterized by postural tremor of the arms. Head, legs, trunk, voice, jaw, and facial muscles also may be involved. The condition can be aggravated by emotions, hunger, fatigue and temperature extremes, and may cause a functional disability or even incapacitation. Inheritance is autosomal dominant.
Wikipedia:69 Essential tremor (ET, also referred to as benign tremor, familial tremor, or idiopathic tremor) is the... more...
UMLS symptoms related to Essential Tremor:essential and other specified forms of tremor, myoclonus, tremor, senile tremor, asterixis, action tremor, static tremor, tremor, neonatal, head titubation, physiological tremor, tremor nec in icd9cm_2014, orthostatic tremor, hyperexplexia
Drugs for Essential Tremor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):(show top 50) (show all 53)
Interventional clinical trials:(show top 50) (show all 191)
Search NIH Clinical Center for Essential Tremor
Inferred drug relations via UMLS66/NDF-RT44:
MalaCards organs/tissues related to Essential Tremor:34
Brain, Cerebellum, Cortex, Testes, Thalamus, Eye, Spinal cord
Articles related to Essential Tremor:(show top 50) (show all 657)
Search GEO for disease gene expression data for Essential Tremor.
Cellular components related to Essential Tremor according to GeneCards Suite gene sharing:
Biological processes related to Essential Tremor according to GeneCards Suite gene sharing:(show all 31)
Molecular functions related to Essential Tremor according to GeneCards Suite gene sharing:
29ICD10 via Orphanet
38MESH via Orphanet
51OMIM via Orphanet
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
67UMLS via Orphanet