MCID: EXT022
MIFTS: 40

Exotropia malady

Eye diseases category

Summaries for Exotropia

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63Wikipedia, 32MalaCards
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Wikipedia:63 Exotropia (from Greek εξοτρὀπια, εξο \"exo\" meaning \"to exit\" or \"move out of\" and... more...

MalaCards: Exotropia, also known as divergent concomitant strabismus, is related to esotropia and congenital nystagmus. An important gene associated with Exotropia is PHOX2A (paired-like homeobox 2a). The compound tunicamycin have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and thyroid, and related mouse phenotype respiratory system.

Aliases & Classifications for Exotropia

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 39NCIt, 27ICD9CM, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

exotropia 8 10 60
divergent concomitant strabismus 8
exotropia, unspecified 8
unspecified exotropia 8
divergent strabismus 8
exotropia nos 8


External Ids:

Disease Ontology8 DOID:1143
NCIt39 C34601
ICD9CM27 378.1, 378.10
MeSH34 D005099
ICD1025 H50.1

Related Diseases for Exotropia

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Exotropia:



Diseases related to exotropia

Clinical Features for Exotropia

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Drugs & Therapeutics for Exotropia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Exotropia

Drug clinical trials:

Search ClinicalTrials for Exotropia

Search NIH Clinical Center for Exotropia

Search CenterWatch for Exotropia

Genetic Tests for Exotropia

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Anatomical Context for Exotropia

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32MalaCards
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MalaCards organs/tissues related to Exotropia:

32
Eye, Testes, Thyroid

Animal Models for Exotropia or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Exotropia:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.0ACAN, PHOX2B, PHOX2A, FOXC2

Publications for Exotropia

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Sources:
50PubMed
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Articles related to Exotropia:

(show top 50)    (show all 495)
idTitleAuthorsYear
1
A prospective study of fusional convergence parameters in Chinese patients with intermittent exotropia. (23911127)
2013
2
Management of large V-pattern exotropia with minimal or no inferior oblique overaction. (24215805)
2013
3
Authors' response: After intermittent exotropia surgery, consecutive esotropia: good or bad? by K K Shoaib. (23493567)
2013
4
Consecutive exotropia. (21724060)
2011
5
Health-related quality of life in parents of children with intermittent exotropia. (21419677)
2011
6
Visual suppression in intermittent exotropia during binocular alignment. (21220559)
2011
7
Evaluation of factors influencing distance stereoacuity on Frisby-Davis Distance Test (FD2) in intermittent exotropia. (20935306)
2011
8
Stability of near stereoacuity in childhood intermittent exotropia. (22108358)
2011
9
Supermaximal recession and resection in large-angle sensory exotropia. (21461229)
2011
10
Postoperative convergence after recovery from general anesthesia in exotropia surgery. (20964275)
2011
11
Comparison of outcomes of unilateral lateral rectus recession for exotropia between first and second operations. (21976940)
2011
12
Magnetic resonance imaging of the medial rectus muscle of patients with consecutive exotropia after medial rectus muscle recession. (20541264)
2010
13
Is initial overcorrection after surgical correction for intermittent exotropia necessary? (20128547)
2010
14
Outcome study of unilateral lateral rectus recession for small to moderate angle intermittent exotropia in children. (19873943)
2010
15
Comparison of quality-of-life instruments in childhood intermittent exotropia. (20417138)
2010
16
Age-related changes of phoria myopia in patients with intermittent exotropia. (19184303)
2009
17
The occurrence of monofixational exotropia after exotropia surgery. (19285655)
2009
18
Role of the equator in the early overcorrection of intermittent exotropia. (19213274)
2009
19
Consecutive exotropia: does one size fit all? (19470998)
2009
20
Diagnostic occlusion test in intermittent exotropia. (18929306)
2008
21
Timing of surgery for primary exotropia in children. (17564939)
2007
22
Consecutive esotropia in intermittent exotropia patients with immediate postoperative overcorrection more than 17 prism diopters. (17804921)
2007
23
Distance stereoacuity in intermittent exotropia. (16885187)
2007
24
Re-recession of the lateral rectus muscles in patients with recurrent exotropia. (16678753)
2006
25
'Largest angle to target' in surgery for intermittent exotropia. (15688062)
2005
26
Potential diagnostic dilemmas using the multifocal electroretinogram in intermittent exotropia. (15317720)
2004
27
The downside of [too much] freedom and liberty: chaos? Plus V-exotropia; screening in France; slipped muscles; a new test for torsion. (15320859)
2004
28
Interventions for intermittent distance exotropia. (12804487)
2003
29
Usefulness of the preoperative prism adaptation test in patients with intermittent exotropia. (12691230)
2003
30
When the patient says no. Management of exotropia with hemianopic visual field defects. (14521505)
2003
31
Consecutive exotropia following strabismus surgery. (12207126)
2002
32
Corneal birth trauma: a cause for sensory exotropia. (11116710)
2000
33
Distance alternate-letter suppression test for objective assessment of sensorial status in intermittent exotropia. (10744198)
2000
34
Botulinum toxin therapy in exotropia. (10366068)
1999
35
Fresnel prism treatment of sensory exotropia with restoration of sensory and motor fusion. (10079453)
1999
36
Slanted lateral rectus recession for exotropia with convergence weakness. (10328402)
1999
37
Exotropia secondary to vitreous hemorrhage. (9085109)
1997
38
Development of compensating exotropia with anomalous retinal correspondence after early infancy in congenital homonymous hemianopia. (7494160)
1995
39
Management of intermittent exotropia using a combination of vision therapy and surgery. (2768754)
1989
40
Intermittent exotropia. (4077421)
1985
41
Accommodation dynamics in divergence excess exotropia. (6706505)
1984
42
Early surgery of infantile exotropia. (6659036)
1983
43
Auditory biofeedback and intermittent exotropia. (7108096)
1982
44
Lateral incomitancy in intermittent exotropia: cause and surgical therapy. (485918)
1979
45
Intermittent exotropia: diagnosis and management. (4719307)
1973
46
Intermittent exotropia. (5155055)
1971
47
A and V patterns in exotropia. An electromyographic study of horizontal rectus muscles. (5635564)
1968
48
Treatment of overcorrected intermittent exotropia. (5659315)
1968
49
SURGICAL RESULTS IN INTERMITTENT EXOTROPIA. (14067267)
1963
50
The surgical treatment of exotropia resulting from anterior internuclear ophthalmoplegia. A practical evaluation of some surgical techniques. (14789933)
1950

Genetic Variations for Exotropia

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Expression for genes affiliated with Exotropia

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Exotropia

Search GEO for disease gene expression data for Exotropia.

Pathways for genes affiliated with Exotropia

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Compounds for genes affiliated with Exotropia

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44Novoseek, 59Tocris Bioscience
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Compounds related to Exotropia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1tunicamycin44 5910.7LMLN, DPAGT1

GO Terms for genes affiliated with Exotropia

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Sources:
16Gene Ontology
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Cellular components related to Exotropia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear chromatinGO:0007909.8PHOX2B, PHOX2A

Biological processes related to Exotropia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1noradrenergic neuron differentiationGO:0033579.9PHOX2B, PHOX2A
2dopaminergic neuron differentiationGO:0715429.8PHOX2B, PHOX2A
3sympathetic nervous system developmentGO:0484859.7PHOX2B, PHOX2A
4positive regulation of transcription from RNA polymerase II promoterGO:0459448.8FOXC2, PHOX2A, PHOX2B, MC1R
5cell adhesionGO:0071558.6ACAN, LMLN, AMTN

Molecular functions related to Exotropia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II regulatory region sequence-specific DNA bindingGO:0009779.8PHOX2B, PHOX2A

Products for genes affiliated with Exotropia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Exotropia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet