MCID: EXT022
MIFTS: 37

Exotropia malady

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Exotropia

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Aliases & Descriptions for Exotropia:

Name: Exotropia 10 12 65
Divergent Concomitant Strabismus 10
 
Divergent Strabismus 10

Classifications:



External Ids:

Disease Ontology10 DOID:1143
ICD1027 H50.1, H50.10
ICD9CM29 378.1, 378.10
MeSH36 D005099
NCIt42 C34601
UMLS65 C0015310

Summaries for Exotropia

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Wikipedia:68 Exotropia (from Greek exo meaning \"outward\" and trope meaning \"a turning\"),divergent squint or wall... more...

MalaCards based summary: Exotropia, also known as divergent concomitant strabismus, is related to hypotropia and alternating exotropia. An important gene associated with Exotropia is ACAN (Aggrecan). Affiliated tissues include eye, breast and heart.

Related Diseases for Exotropia

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Diseases related to Exotropia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 60)
idRelated DiseaseScoreTop Affiliating Genes
1hypotropia29.7CHN1, ROBO3
2alternating exotropia12.2
3monocular exotropia12.0
4esotropia10.4
5strabismus10.4
6meckel syndrome 310.3CHN1, KIF21A
7autism susceptibility 1710.3KIF21A, PHOX2A
8cyclotropia10.2CHN1, KIF21A
9sclerosteosis10.2ACAN, FBN1
10sensorineural hearing loss10.2KIF21A, PHOX2A
11retinitis10.1
12myopia10.1
13internuclear ophthalmoplegia10.1
14ophthalmoplegia10.1
15hypertropia10.1
16partial third-nerve palsy10.0CHN1, KIF21A, PHOX2A
17total circumpapillary dystrophy of choroid10.0CHN1, KIF21A, PHOX2A
18ametropic amblyopia10.0CHN1, KIF21A, PHOX2A
19clear cell adenoma10.0KIF21A, PHOX2A
20lipid-rich carcinoma10.0CHN1, KIF21A, PHOX2A
21water-clear cell adenoma10.0CHN1, KIF21A, PHOX2A
22amblyopia9.9
23accommodative esotropia9.9
24idiopathic scoliosis9.9FBN1, ROBO3
25bone resorption disease9.9ACAN, FBN1, ROBO3
26keratoconus9.8
27ptosis9.8
28refractive error9.8
29neurologic diseases9.8
30gallbladder disease9.8KIF21A, PHOX2A
31medulloblastoma9.7
32attention deficit-hyperactivity disorder9.7
33crouzon syndrome9.7
34marfan syndrome9.7
35cataract9.7
36diamond-blackfan anemia9.7
37myasthenia gravis9.7
38retinitis pigmentosa9.7
39cone dystrophy9.7
40tetanus9.7
41choroiditis9.7
42accommodative spasm9.7
43presbyopia9.7
44astigmatism9.7
45duane retraction syndrome9.7
46abnormal retinal correspondence9.7
47congenital toxoplasmosis9.7
48dermoid cyst9.7
49cavernous sinus meningioma9.7
50eye disease9.7

Graphical network of the top 20 diseases related to Exotropia:



Diseases related to exotropia

Symptoms for Exotropia

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Drugs & Therapeutics for Exotropia

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Drugs for Exotropia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AcetylcholineexperimentalPhase 468951-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
Miochol E
O-Acetylcholine
acetylcholine chloride
2Neurotransmitter AgentsPhase 414795
3AbobotulinumtoxinAPhase 4588
4Pharmaceutical SolutionsPhase 47004
5Neuromuscular AgentsPhase 4922
6Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 318510
7OnabotulinumtoxinAPhase 4588
8IncobotulinumtoxinAPhase 4599
9Botulinum Toxins, Type APhase 4588
10Botulinum ToxinsPhase 4616
11Cholinergic AgentsPhase 43243
12
Bupivacaineapproved, investigationalPhase 2, Phase 39642180-92-92474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Hydrochloride
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
DepoBupivacaine
 
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
Exparel
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
Racemic bupivacaine
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Vivacaine
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
13
EpinephrineapprovedPhase 2, Phase 383451-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
14Epinephryl boratePhase 2, Phase 3834
15RacepinephrinePhase 2, Phase 3834
16Anesthetics, LocalPhase 2, Phase 32347
17AnestheticsPhase 2, Phase 37385
18Central Nervous System DepressantsPhase 2, Phase 310016

Interventional clinical trials:

(show all 16)
idNameStatusNCT IDPhase
1Comparison of Two Treatments for Strabismus Correction: Botulinum Toxin A Associated to Surgery and Surgery AloneCompletedNCT01460355Phase 4
2A Pilot Clinical Trial of Overminus Spectacle Therapy for Intermittent ExotropiaCompletedNCT02223650Phase 2, Phase 3
3Orthoptic Changes Following Photorefractive KeratectomyCompletedNCT01279993Phase 3
4Bupivacaine Injection of Eye Muscles to Treat StrabismusRecruitingNCT01616108Phase 2, Phase 3
5Study of Non-surgical Treatment Versus Observation in Asian Children With Intermittent ExotropiaTerminatedNCT01267500Phase 2
6Early Results of Slanted Recession of the Lateral Rectus Muscle for Intermittent Exotropia With Convergence WeaknessCompletedNCT02131792
7Observation Versus Occlusion Therapy for Intermittent ExotropiaCompletedNCT01032330
8Surgery and Convergence Insufficiency Intermittent ExotropiaCompletedNCT01435876
9Lateral Rectus Muscle and Anterior Segment Optical Coherence Tomography (AS-OCT)CompletedNCT02383381
10Study of Surgical Treatment Versus Observation in Children With Moderate Intermittent ExotropiaRecruitingNCT02736526
11Controlled Intermittent Alternate Occlusion (CIAO) Therapy for Intermittent ExotropiaRecruitingNCT02466659
12Protective Effect of Biodegradable Collagen Implant (Ologen) in Scleral Thinning After Strabismus SurgeryRecruitingNCT02699580
13Strabismus Surgery and Driving AbilityRecruitingNCT02570555
14Assessing the Functional and Psychosocial Impact of Strabismus in Asian Children Using the AS-20 and IXTQ QuestionnairesRecruitingNCT01608828
15Bilateral Lateral Rectus Recession Versus Unilateral Recess-Resect for Intermittent ExotropiaActive, not recruitingNCT01032603
16Lateral Rectus Muscle and Anterior Segment Optical Coherence Tomography (AS-OCT) in Two Recession SurgeriesNot yet recruitingNCT02450162

Search NIH Clinical Center for Exotropia

Genetic Tests for Exotropia

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Anatomical Context for Exotropia

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MalaCards organs/tissues related to Exotropia:

33
Eye, Breast, Heart, Testes, Lung, Bone, Prostate

Animal Models for Exotropia or affiliated genes

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Publications for Exotropia

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Articles related to Exotropia:

(show top 50)    (show all 579)
idTitleAuthorsYear
1
Long-term Cosmetic Alignment Following Surgery for Esotropia Versus Exotropia in Childhood: A Comparison Using Survival Curves. (26444493)
2015
2
Bilateral superior rectus transposition for congenital exotropia associated withA anomalous medial rectusA muscles. (26486030)
2015
3
Improvement in fusion and stereopsis following surgery for intermittent exotropia. (25643371)
2015
4
Efficacy of Botulinum Toxin in the treatment of Intermittent Exotropia. (25313677)
2014
5
Traditional and reduced recession surgical dosage for bilateral lateral rectus recession for infantile exotropia. (24825843)
2014
6
Lateral incomitancy and surgical results in intermittent exotropia. (24831714)
2014
7
The clinical course of recurrent intermittent exotropia following one or two surgeries over 24 months postoperatively. (24788017)
2014
8
Unilateral strabismus surgery in patients with exotropia results in postoperative lateral incomitance. (25498465)
2014
9
Evaluation of FD2 (Frisby Davis distance) stereotest in surgical management of intermittent exotropia. (23902676)
2013
10
A prospective study of fusional convergence parameters in Chinese patients with intermittent exotropia. (23911127)
2013
11
Acute onset of upbeat nystagmus, exotropia, and internuclear ophthalmoplegia--a tell-tale of ponto-mesencephalic infarct. (23830476)
2013
12
Analysis of risk factors for consecutive exotropia and review of the literature. (23641958)
2013
13
Ocular torsion among patients with intermittent exotropia: relationships with disease severity factors. (23022165)
2013
14
Risk factors for consecutive exotropia. (24079667)
2013
15
Age-related changes of phoria myopia in patients with intermittent exotropia. (19184303)
2009
16
Reversal of unilateral medial rectus recession and lateral rectus resection for the correction of consecutive exotropia. (19471001)
2009
17
Sensory adaptation in exophoria and exotropia. (21149193)
2009
18
The Comparison of outcomes between lateral rectus muscles re-recession and medial rectus muscles resection in recurrent exotropia. (18612229)
2008
19
Quality of life in intermittent exotropia: child and parent concerns. (19001219)
2008
20
Increasing exotropia and decreasing vision in a school-aged boy. (18029273)
2007
21
The use of the Newcastle Control Score in the management of intermittent exotropia. (17020901)
2007
22
Recession-resection combined with intraoperative botulinum toxin A chemodenervation for exotropia following subtotal ruptured of medial rectus muscle. (16628422)
2007
23
Interventions for intermittent exotropia. (16856017)
2006
24
The natural history of surgically untreated intermittent exotropia-looking into the distant future. (16814175)
2006
25
Interventions for intermittent distance exotropia. (12804487)
2003
26
Field expansion for homonymous hemianopia by optically induced peripheral exotropia. (11014672)
2000
27
Treatment for "A" and "V" exotropia by slanting muscle insertions. (10974302)
2000
28
Grand rounds #51: a case of consecutive exotropia after medial rectus recession for Duane syndrome. (9780416)
1998
29
Long-term results of botulinum toxin in consecutive and secondary exotropia: outcome in patients initially treated with botulinum toxin. (10532736)
1998
30
Exotropia secondary to vitreous hemorrhage. (9085109)
1997
31
Infantile exotropia. (8965243)
1996
32
The outcome of strabismus surgery in childhood exotropia. (8925940)
1996
33
Excess cyclovergence in patients with intermittent exotropia. (8560798)
1995
34
Secondary exotropia: a retrospective analysis of matched cases. (8350225)
1993
35
Treatment options in intermittent exotropia: a critical appraisal. (1594200)
1992
36
The use of part-time occlusion for early onset unilateral exotropia. (2709283)
1989
37
Orthophorization after occlusion-induced exotropia. (3777126)
1986
38
Intermittent exotropia. (4077421)
1985
39
Stimulus and response AC/A ratios in intermittent exotropia of the divergence-excess type. (7082610)
1982
40
Undercorrected exotropia. (7162766)
1982
41
The effect of preoperative convergence exercises on the surgical outcome of primary exotropia. (555804)
1979
42
Orthoptic treatment of constant and intermittent exotropia. (749588)
1978
43
Therapeutic uses of prisms in undercorrected intermittent exotropia. (5155079)
1971
44
INTERMITTENT EXOTROPIA. (14166229)
1964
45
RIGHT-ANGLE EXOTROPIA. (14233724)
1964
46
Surgical results following the recession-resection operation for intermittent exotropia. (13866485)
1962
47
48
49
50

Variations for Exotropia

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Expression for genes affiliated with Exotropia

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Search GEO for disease gene expression data for Exotropia.

Pathways for genes affiliated with Exotropia

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GO Terms for genes affiliated with Exotropia

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Biological processes related to Exotropia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1dopaminergic neuron differentiationGO:00715429.6PHOX2A, PHOX2B

Sources for Exotropia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet