MCID: EXT022
MIFTS: 33

Exotropia malady

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Exotropia

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Aliases & Descriptions for Exotropia:

Name: Exotropia 10 12 65
Divergent Concomitant Strabismus 10
 
Divergent Strabismus 10

Classifications:



External Ids:

Disease Ontology10 DOID:1143
ICD1027 H50.1, H50.10
ICD9CM29 378.1, 378.10
MeSH36 D005099
NCIt42 C34601
UMLS65 C0015310

Summaries for Exotropia

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Wikipedia:68 Exotropia (from Greek exo meaning \"outward\" and trope meaning \"a turning\"),divergent squint or wall... more...

MalaCards based summary: Exotropia, also known as divergent concomitant strabismus, is related to alternating exotropia and monocular exotropia. An important gene associated with Exotropia is ACAN (Aggrecan). Affiliated tissues include eye, lung and prostate.

Related Diseases for Exotropia

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Graphical network of the top 20 diseases related to Exotropia:



Diseases related to exotropia

Symptoms for Exotropia

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Drugs & Therapeutics for Exotropia

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Drugs for Exotropia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AcetylcholineexperimentalPhase 468951-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
Miochol E
O-Acetylcholine
acetylcholine chloride
2Neurotransmitter AgentsPhase 414795
3AbobotulinumtoxinAPhase 4588
4Pharmaceutical SolutionsPhase 47004
5Neuromuscular AgentsPhase 4922
6Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 318510
7OnabotulinumtoxinAPhase 4588
8IncobotulinumtoxinAPhase 4599
9Botulinum Toxins, Type APhase 4588
10Botulinum ToxinsPhase 4616
11Cholinergic AgentsPhase 43243
12
Bupivacaineapproved, investigationalPhase 2, Phase 39642180-92-92474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Hydrochloride
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
DepoBupivacaine
 
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
Exparel
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
Racemic bupivacaine
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Vivacaine
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
13
EpinephrineapprovedPhase 2, Phase 383451-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
14Epinephryl boratePhase 2, Phase 3834
15RacepinephrinePhase 2, Phase 3834
16Anesthetics, LocalPhase 2, Phase 32347
17AnestheticsPhase 2, Phase 37385
18Central Nervous System DepressantsPhase 2, Phase 310016

Interventional clinical trials:

(show all 16)
idNameStatusNCT IDPhase
1Comparison of Two Treatments for Strabismus Correction: Botulinum Toxin A Associated to Surgery and Surgery AloneCompletedNCT01460355Phase 4
2A Pilot Clinical Trial of Overminus Spectacle Therapy for Intermittent ExotropiaCompletedNCT02223650Phase 2, Phase 3
3Orthoptic Changes Following Photorefractive KeratectomyCompletedNCT01279993Phase 3
4Bupivacaine Injection of Eye Muscles to Treat StrabismusRecruitingNCT01616108Phase 2, Phase 3
5Study of Non-surgical Treatment Versus Observation in Asian Children With Intermittent ExotropiaTerminatedNCT01267500Phase 2
6Early Results of Slanted Recession of the Lateral Rectus Muscle for Intermittent Exotropia With Convergence WeaknessCompletedNCT02131792
7Observation Versus Occlusion Therapy for Intermittent ExotropiaCompletedNCT01032330
8Surgery and Convergence Insufficiency Intermittent ExotropiaCompletedNCT01435876
9Lateral Rectus Muscle and Anterior Segment Optical Coherence Tomography (AS-OCT)CompletedNCT02383381
10Study of Surgical Treatment Versus Observation in Children With Moderate Intermittent ExotropiaRecruitingNCT02736526
11Controlled Intermittent Alternate Occlusion (CIAO) Therapy for Intermittent ExotropiaRecruitingNCT02466659
12Protective Effect of Biodegradable Collagen Implant (Ologen) in Scleral Thinning After Strabismus SurgeryRecruitingNCT02699580
13Strabismus Surgery and Driving AbilityRecruitingNCT02570555
14Assessing the Functional and Psychosocial Impact of Strabismus in Asian Children Using the AS-20 and IXTQ QuestionnairesRecruitingNCT01608828
15Bilateral Lateral Rectus Recession Versus Unilateral Recess-Resect for Intermittent ExotropiaActive, not recruitingNCT01032603
16Lateral Rectus Muscle and Anterior Segment Optical Coherence Tomography (AS-OCT) in Two Recession SurgeriesNot yet recruitingNCT02450162

Search NIH Clinical Center for Exotropia

Genetic Tests for Exotropia

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Anatomical Context for Exotropia

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MalaCards organs/tissues related to Exotropia:

33
Eye, Lung, Prostate, Breast, T cells, Pituitary, Liver

Animal Models for Exotropia or affiliated genes

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Publications for Exotropia

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Articles related to Exotropia:

(show top 50)    (show all 554)
idTitleAuthorsYear
1
Parental Stress in Families of Children With Autism and Other Developmental Disabilities. (25862740)
2015
2
Comparison of Cardiorespiratory Responses During Aquatic and Land Treadmill Exercise in Patients With Coronary Artery Disease. (25407597)
2014
3
Protective ventilation of preterm lambs exposed to acute chorioamnionitis does not reduce ventilation-induced lung or brain injury. (25379714)
2014
4
Recommendations for HLA-B*15:02 and HLA-A*31:01 genetic testing to reduce the risk of carbamazepine-induced hypersensitivity reactions. (24597466)
2014
5
FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents. (25071006)
2014
6
Association of polymorphisms in microRNA machinery genes (DROSHA, DICER1, RAN, and XPO5) with risk of idiopathic primary ovarian insufficiency in Korean women. (23549446)
2013
7
Outcome of management of otosclerosis by stapedotomy compared to stapedectomy in a jordanian population. (23386943)
2013
8
Severe invasive listeriosis--case report. (23272533)
2012
9
Barrett's esophagus: treatments of adenocarcinomas II. (21950818)
2011
10
IgA pemphigus and pustular psoriasis: a possible relation. (21233060)
2011
11
Mitral valve replacement via right thoracotomy approach for prevention of mediastinitis in a female patient with long-term uncontrolled diabetes mellitus: a case report. (20478046)
2010
12
Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells. (19054297)
2009
13
Lattice corneal dystrophy, gelsolin type (Meretoja's syndrome). (19832730)
2009
14
Education and imaging. Hepatobiliary and pancreatic: Large cavernous hemangioma with obstructive jaundice. (19646022)
2009
15
Lyme arthritis presenting as transient synovitis of the hip. (18519920)
2008
16
High frequency of submicroscopic chromosomal imbalances in patients with syndromic craniosynostosis detected by a combined approach of microsatellite segregation analysis, multiplex ligation-dependent probe amplification and array-based comparative genome hybridisation. (18456720)
2008
17
Structure and function of beta -1,4-galactosyltransferase. (18393823)
2008
18
Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells. (18006848)
2007
19
Analysis of two imported cases of yellow fever infection from Ivory Coast and The Gambia to Germany and Belgium. (16036176)
2005
20
The diagnostic role of urinary N-acetyl-beta-D-glucosaminidase (NAG) activity in the detection of renal tubular impairment. (16259316)
2005
21
Effect of ketoconazole on the pharmacokinetics and safety of telithromycin and clarithromycin in older subjects with renal impairment. (15792396)
2005
22
Mutant torsinA, which causes early-onset primary torsion dystonia, is redistributed to membranous structures enriched in vesicular monoamine transporter in cultured human SH-SY5Y cells. (15593317)
2005
23
Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway. (14729063)
2004
24
Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb. (12646568)
2003
25
Clinical pharmacokinetics of statins. (12949632)
2003
26
Regulatory regions driving developmental and tissue-specific expression of the essential pancreatic gene pdx1. (11784003)
2001
27
Vaccination against bubonic and pneumonic plague. (11457543)
2001
28
Human homologues of yeast vacuolar protein sorting 29 and 35. (11062004)
2000
29
Activation of NADPH oxidase in Alzheimer's disease brains. (10873554)
2000
30
The ubiquitin carboxy-terminal hydrolase-L1 gene S18Y polymorphism does not confer protection against idiopathic Parkinson's disease. (11027850)
2000
31
Regression of myocardial fibrosis in hypertensive heart disease: diverse effects of various antihypertensive drugs. (10773237)
2000
32
Epidemiology of dystrophinopathies in North-West Tuscany: a molecular genetics-based revisitation. (10466417)
1999
33
Malignant peripheral nerve sheath tumor in a water moccasin (Agkistrodon piscivorus). (9580548)
1998
34
Predisposition of Wolfram syndrome heterozygotes to psychiatric illness. (9491819)
1998
35
Early temporalis muscle transposition for the management of facial paralysis. (7666737)
1995
36
Lesions in oculocerebrorenal syndrome. (7847233)
1994
37
Premature arrest of myelin formation in transgenic mice with increased proteolipid protein gene dosage. (7512350)
1994
38
A phase I study of escalating interferon alpha-2a combined with 5-fluorouracil and leucovorin in patients with gastrointestinal malignancies. (8217238)
1993
39
Effect of betaine on HSP70 expression and cell survival during adaptation to osmotic stress. (8343134)
1993
40
Low order correlations of lipoprotein(a) with other blood lipids and with coagulation and fibrinolysis parameters in hypertensive and diabetic patients. (1386533)
1992
41
Anticardiolipin antibodies and the risk for ischemic stroke and venous thrombosis. (1443986)
1992
42
Acrorenal syndrome: further observations. (1342854)
1992
43
Chromosomal localization of the human osteocalcin gene. (2785029)
1989
44
Sequence organization of the human int-2 gene and its expression in teratocarcinoma cells. (2470007)
1989
45
Treatment of intractable coccygodynia by transsacral ammonium chloride injection. (4934170)
1971
46
Progeria; report of a case. (13578348)
1958
47
48
49
50

Variations for Exotropia

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Expression for genes affiliated with Exotropia

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Search GEO for disease gene expression data for Exotropia.

Pathways for genes affiliated with Exotropia

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GO Terms for genes affiliated with Exotropia

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Biological processes related to Exotropia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1dopaminergic neuron differentiationGO:00715429.6PHOX2A, PHOX2B

Sources for Exotropia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet