MCID: EXT010
MIFTS: 58

Extramedullary Plasmacytoma malady

Cancer diseases category

Summaries for Extramedullary Plasmacytoma

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34MalaCards
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MalaCards: Extramedullary Plasmacytoma, also known as plasmacytoma, extramedullary, is related to plasmacytoma and multiple myeloma. An important gene associated with Extramedullary Plasmacytoma is IL2RB (interleukin 2 receptor, beta), and among its related pathways are IL-7 Signaling and its Primary Biological Effects in Different Immune Cell Types and IL12-mediated signaling events. The compounds optimax and bryostatin 1 have been mentioned in the context of this disorder. Affiliated tissues include bone, thyroid and colon, and related mouse phenotypes are vision/eye and liver/biliary system.

Aliases & Classifications for Extramedullary Plasmacytoma

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9Disease Ontology, 63UMLS, 59SNOMED-CT, 41NCIt, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

extramedullary plasmacytoma 9 63
plasmacytoma, extramedullary 9
extraosseous plasmacytoma 9


External Ids:

Disease Ontology9 DOID:3720
NCIt41 C4002
ICD1026 C90.2

Related Diseases for Extramedullary Plasmacytoma

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18GeneCards, 19GeneDecks
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Diseases related to Extramedullary Plasmacytoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 141)
idRelated DiseaseScoreTop Affiliating Genes
1plasmacytoma32.2IL6, B2M, IGKC
2multiple myeloma31.1B2M, CCND1, IL6, BCL2L1
3myeloma30.8CDKN1A, IGKC, BCL2L1, BCL2, IL6, IL2
4malt lymphoma30.5IGKC, CCND1, BCL2
5plasma cell leukemia30.3CCND1, IL6
6sarcoidosis30.3BCL2L1, IL2RB, IL2
7kaposi's sarcoma30.2IL6
8adenoma30.2CCND1, IFI27, BCL2, CDKN1A
9hodgkin's lymphoma30.2IL2, IL2RB, BCL2, BCL2L1
10adenocarcinoma30.0VEGFA, CCND1, IFI27, BCL2, BCL2L1, CDKN1A
11breast cancer30.0VEGFA, CCND1, IFI27, IL2, BCL2, BCL2L1
12melanoma29.9VEGFA, CCND1, IFI27, IL2, IL2RB, BCL2
13leukemia29.8IGKC, B2M, CCND1, IFI27, IL2, IL2RB
14thyroiditis10.7
15tonsillitis10.5
16mediastinitis10.5
17amyloidosis10.4
18cervicitis10.4
19sinusitis10.4
20intussusception10.3
21nasopharyngitis10.3
22obstructive jaundice10.3
23pancreatitis10.3
24sarcoma10.3
25cardiac tamponade10.2
26extrahepatic cholestasis10.2
27cholestasis10.2
28plasmablastic lymphoma10.2
29crohn's disease10.1
30tolosa-hunt syndrome10.1
31oral squamous cell carcinoma10.1
32exophthalmos10.1
33sialadenitis10.1
34ulcerative colitis10.1
35duodenitis10.1
36adenoiditis10.1
37papillary carcinoma10.1
38choroiditis10.1
39orbital cellulitis10.1
40multinodular goiter10.1
41macroglobulinemia10.1
42solitary osseous plasmacytoma10.1
43cellulitis10.1
44dacryocystitis10.1
45dermatomyositis10.1
46gingival overgrowth10.1
47gingivitis10.1
48goiter10.1
49islet cell tumor10.1
50lymphadenitis10.1

Graphical network of the top 20 diseases related to Extramedullary Plasmacytoma:



Diseases related to extramedullary plasmacytoma

Symptoms for Extramedullary Plasmacytoma

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Drugs & Therapeutics for Extramedullary Plasmacytoma

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Extramedullary Plasmacytoma

Drug clinical trials:

Search ClinicalTrials for Extramedullary Plasmacytoma

Search NIH Clinical Center for Extramedullary Plasmacytoma

Search CenterWatch for Extramedullary Plasmacytoma

Genetic Tests for Extramedullary Plasmacytoma

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Anatomical Context for Extramedullary Plasmacytoma

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34MalaCards
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MalaCards organs/tissues related to Extramedullary Plasmacytoma:

34
Bone, Thyroid, Colon, Breast, Pancreas, Tongue, Lymph node, Tonsil, Heart, Small intestine, Skin, Salivary gland, Bone marrow, Lung, Liver, Adrenal gland, Trachea, Skeletal muscle, Testis, Kidney, B cells, Spinal cord, Pituitary

Animal Models for Extramedullary Plasmacytoma or affiliated genes

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38MGI
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Publications for Extramedullary Plasmacytoma

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53PubMed
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Articles related to Extramedullary Plasmacytoma:

(show top 50)    (show all 438)
idTitleAuthorsYear
1
Extramedullary plasmacytoma in the lung of a Doberman pinscher dog. (24381343)
2014
2
Primary extramedullary plasmacytoma of the heart: a rare manifestation of plasmacellular tumor. (24386583)
2013
3
Pathology quiz case 2. Extramedullary plasmacytoma (EMP). (23429957)
2013
4
Dacryocystitis provoked by recurrence of extramedullary plasmacytoma of the orbit: a case report. (20437877)
2010
5
Extramedullary plasmacytoma of the tongue base: a case report and clinical review of head and neck plasmacytoma. (20737375)
2010
6
Radiotherapy for extramedullary plasmacytoma of the head and neck. (18707826)
2009
7
Synchronous oral squamous cell carcinoma and extramedullary plasmacytoma of the tonsil. (19570691)
2009
8
Incidental detection of concurrent extramedullary plasmacytoma and amyloidoma of the nasopharynx on [18F]fluorodeoxyglucose positron emission tomography/computed tomography. (19001338)
2008
9
Extramedullary plasmacytoma in the maxillary sinus. (19037537)
2008
10
Extramedullary plasmacytoma of the tonsil diagnosed by fine-needle aspiration cytology. (18164414)
2008
11
Extramedullary plasmacytoma of the nasal sinus cavities. (17162133)
2007
12
Multifocal extramedullary plasmacytoma with paraproteinemia, pleural involvement and retroperitoneal lymphadenopathy: an uncommon pattern of relapse of solitary osseous plasmacytoma. (16496148)
2006
13
Cytopathology of extramedullary plasmacytoma of the bladder: a case report. (16780033)
2006
14
Extramedullary plasmacytoma of the salivary gland in two Syrian hamsters (Mesocricetus auratus). (16301579)
2005
15
Extramedullary plasmacytoma immunoglobulin D (lambda) in the chest wall and the subglottic region. (15867795)
2005
16
Primary extramedullary plasmacytoma and multiple myeloma: phenotypic differences revealed by immunohistochemical analysis. (15586381)
2005
17
A case of extramedullary plasmacytoma arising from the posterior mediastinum. (16134775)
2005
18
Uterine extramedullary plasmacytoma in a dog. (15200080)
2004
19
Unilateral exophthalmos caused by an extramedullary plasmacytoma: a case report. (23365508)
2003
20
Solitary extramedullary plasmacytoma of the premaxilla. (12780455)
2003
21
A case of Crow-Fukase syndrome with extramedullary plasmacytoma: marked clinical deterioration following a biopsy to plasmacytoma]. (12884826)
2003
22
Extramedullary plasmacytoma of the submandibular gland. (11779340)
2001
23
A case of retroperitoneal extramedullary plasmacytoma with multiple metastases. (11368939)
2000
24
Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts. (10618630)
2000
25
Extramedullary plasmacytoma of the orbit. (11037925)
2000
26
Clinical outcome of extramedullary plasmacytoma. (10629591)
2000
27
Extramedullary plasmacytoma of the head and neck associated with the human immunodeficiency virus. (9473836)
1998
28
Intestinal extramedullary plasmacytoma associated with amyloid deposition in three dogs: an ultrastructural and immunoelectron microscopic study. (9887482)
1998
29
Extramedullary plasmacytoma: a localized or systemic disease? (9441581)
1998
30
Histologic diagnosis and surgical management of primary extramedullary plasmacytoma in the middle ear cavity. (8817034)
1996
31
Fine-needle aspiration of pancreatic extramedullary plasmacytoma: possible confusion with islet cell tumor. (7924813)
1994
32
Extramedullary plasmacytoma of the heart presenting as cardiac emergency. Review of literature. (8092116)
1994
33
Extramedullary plasmacytoma of the head and neck. (7850655)
1994
34
Primary cutaneous extramedullary plasmacytoma secreting lambda IgG. (8403475)
1993
35
Metastatic extramedullary plasmacytoma of the colon and rectum in a dog. (7693631)
1993
36
A rare case of extramedullary plasmacytoma in the mediastinum. (1300172)
1992
37
Solitary conjunctival extramedullary plasmacytoma. (2350120)
1990
38
Extramedullary plasmacytoma of the testicle. Sonographic appearance and ultrasonically guided biopsy. (2198076)
1990
39
Unusual presentations of extramedullary plasmacytoma in the head and neck. (3343553)
1988
40
Anaplastic solitary extramedullary plasmacytoma of the cecum. Report of a case confirmed by immunoperoxidase staining. (3315510)
1987
41
Extramedullary plasmacytoma of the lung. (4005784)
1985
42
Extramedullary plasmacytoma of the bladder: a case report and review of literature. (7083118)
1982
43
Extramedullary plasmacytoma of the head and neck. (6792654)
1981
44
Extramedullary plasmacytoma of the parotid gland. (7359969)
1980
45
Mediastinal extramedullary plasmacytoma. (7375991)
1980
46
Extramedullary plasmacytoma of the gastrointestinal tract in a renal transplant recipient. (380262)
1979
47
Extramedullary plasmacytoma of the colon: a rare cause of intussusception. (889191)
1977
48
Solitary extramedullary plasmacytoma of the head and neck. (1198778)
1975
49
The extramedullary plasmacytoma, benign or malignant? (4500485)
1972
50
Extramedullary plasmacytoma of the head and neck. (5659409)
1968

Variations for Extramedullary Plasmacytoma

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Expression for genes affiliated with Extramedullary Plasmacytoma

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Extramedullary Plasmacytoma

Search GEO for disease gene expression data for Extramedullary Plasmacytoma.

Pathways for genes affiliated with Extramedullary Plasmacytoma

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Sources:
51PathCards, 55R&D Systems, 54QIAGEN, 39NCBI BioSystems Database, 61Thomson Reuters, 31KEGG, 56Reactome, 5Cell Signaling Technology, 58SinoBiological, 13EMD Millipore
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Pathways related to Extramedullary Plasmacytoma according to GeneCards/GeneDecks:

(show top 50)    (show all 78)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5BCL2L1, BCL2
2
Show member pathways
Immune response IL 12 induced IFN gamma production61
9.5B2M, IL2, IL2RB
3
Show member pathways
Ras signaling in the CD4+ TCR pathway39
9.5B2M, IL2RB, IL2
49.4CCND1, BCL2, CDKN1A
59.4CDKN1A, CCND1, BCL2
6
Show member pathways
Signal transduction PTEN pathway61
9.4CCND1, CDKN1A, BCL2
7
Show member pathways
9.4IL2RB, IL2, BCL2
8
Show member pathways
IL-2 Signaling pathway39
9.4IL2, IL2RB, BCL2
9
Show member pathways
PLK2 and PLK4 events39
Polo-like kinase signaling events in the cell cycle39
9.4CDKN1A, IL6, CCND1
10
Show member pathways
Translation Non genomic rapid action of Androgen Receptor61
9.4CCND1, IL6, CDKN1A
11
Show member pathways
9.4IL6, IL2RB, IL2
129.3IL6, CCND1, IL2
139.3CCND1, IL6, BCL2
14
Show member pathways
Development Thrombopoetin signaling via JAK STAT pathway61
9.3CDKN1A, CCND1, BCL2L1
159.3IL2, CDKN1A, IL6
169.3CDKN1A, IL6, BCL2
179.2BCL2L1, BCL2, CCND1
189.2VEGFA, CDKN1A, BCL2
19
Show member pathways
Apoptosis and survival Apoptotic TNF family pathways61
9.2BCL2L1, BCL2, CDKN1A
209.2CCND1, BCL2L1, IL6
219.2IL2, BCL2L1, BCL2
22
Show member pathways
9.1CCND1, BCL2, IL2, IL2RB
23
Show member pathways
9.1BCL2L1, BCL2, IL6
24
Show member pathways
9.1IL6, IL2RB, CCND1, IL2
25
Show member pathways
9.0IL6, CCND1, B2M, IL2
268.9BCL2, CDKN1A, CCND1, VEGFA
27
Show member pathways
Signaling Pathways in Glioblastoma39
8.9VEGFA, CDKN1A, BCL2, CCND1
288.9VEGFA, CCND1, CDKN1A, BCL2
29
Show member pathways
8.9BCL2L1, BCL2, CDKN1A, CCND1
30
Show member pathways
IL2 signaling events mediated by STAT539
8.9BCL2L1, IL2RB, BCL2, IL2
31
Show member pathways
Immune response IL 22 signaling pathway61
G protein signaling N RAS regulation pathway61
8.9IL2, IL2RB, BCL2L1, BCL2
328.9IL6, CDKN1A, IL2RB, BCL2L1
338.9CCND1, IL6, BCL2L1, CDKN1A
34
Show member pathways
8.8CDKN1A, BCL2L1, CCND1, VEGFA
358.7VEGFA, CDKN1A, BCL2, IL6
36
Show member pathways
IL-9 Signaling Pathway39
Development Thrombopoietin regulated cell processes61
IL-7 Signaling Pathway39
Immune response IL 9 signaling pathway61
8.7CDKN1A, IL2, IL2RB, CCND1, IL6
37
Show member pathways
8.7IL6, BCL2L1, BCL2, IL2
38
Show member pathways
Toll-like receptor signaling pathway39
Regulation of toll-like receptor signaling pathway39
8.6BCL2, CDKN1A, IL6, CCND1, IL2
39
Show member pathways
Proteasome Degradation39
Immune response Antigen presentation by MHC class I61
8.6CDKN1A, BCL2L1, CCND1, BCL2, B2M
40
Show member pathways
Type III interferon signaling39
8.5IL6, BCL2L1, CCND1, IL2, IL2RB
41
Show member pathways
Immune response IL 4 signaling pathway61
Signal transduction AKT signaling61
8.5BCL2L1, IGKC, CCND1, CDKN1A
42
Show member pathways
8.4IL6, IL2, IL2RB, IFI27, B2M
43
Show member pathways
IL23-mediated signaling events39
Immune response IL 10 signaling pathway61
Angiopoietin receptor Tie2-mediated signaling39
Development PDGF signaling via STATs and NF kB61
Development Angiopoietin Tie2 signaling61
8.4CDKN1A, BCL2L1, BCL2, IL6, IL2
44
Show member pathways
8.3IL2, CCND1, IL2RB, IL6, BCL2, CDKN1A
458.2BCL2L1, CDKN1A, IL2, IL2RB, IL6, CCND1
46
Show member pathways
8.1IL2, IL6, CDKN1A, BCL2L1, CCND1, BCL2
477.9CCND1, BCL2L1, CDKN1A, BCL2, IL6, VEGFA
48
Show member pathways
7.8IL2RB, CDKN1A, BCL2L1, BCL2, IL6, IL2
49
Show member pathways
7.6IL2, CDKN1A, IL2RB, IL6, BCL2, BCL2L1
507.3CDKN1A, VEGFA, CCND1, IL2, IL2RB, IL6

Compounds for genes affiliated with Extramedullary Plasmacytoma

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Sources:
46Novoseek, 62Tocris Bioscience, 30IUPHAR, 52PharmGKB, 12DrugBank, 25HMDB, 3BitterDB
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Compounds related to Extramedullary Plasmacytoma according to GeneCards/GeneDecks:

(show top 50)    (show all 202)
idCompoundScoreTop Affiliating Genes
1optimax469.5CDKN1A, CCND1, IFI27
2bryostatin 1469.2IL2RB, BCL2, BCL2L1, CDKN1A
32,5-oligoadenylate469.0IL6, IL2RB, IL2, B2M
4eb 108946 6210.0CCND1, IFI27, CDKN1A, BCL2
5ciglitazone46 309.9CCND1, CDKN1A, BCL2L1, IL6
6geldanamycin46 52 62 1211.8CCND1, CDKN1A, BCL2L1, IL2RB, VEGFA
7adriamycin468.8CCND1, BCL2, BCL2L1, CDKN1A, B2M
8triptolide468.8BCL2, VEGFA, IL2, IL6
9rituximab46 52 1210.8BCL2L1, IL6, IL2, B2M, BCL2
10flavopiridol46 129.8CDKN1A, VEGFA, BCL2L1, CCND1, BCL2
11sp 60012546 629.8CCND1, BCL2L1, CDKN1A, BCL2, IL6
12gm-csf46 309.8IL2, IL6, BCL2L1, VEGFA
13gemcitabine46 52 1210.7BCL2L1, CCND1, CDKN1A, VEGFA, BCL2
14indole-3-carbinol468.7BCL2L1, BCL2, IFI27, CDKN1A, CCND1
15sulindac46 129.7IFI27, CDKN1A, BCL2L1, CCND1, BCL2
16roscovitine468.7IFI27, CCND1, BCL2, BCL2L1, CDKN1A
17adpribose468.6CCND1, IFI27, BCL2, BCL2L1, CDKN1A
18troglitazone46 30 62 1211.6CDKN1A, CCND1, IL6, IFI27, BCL2
19egcg468.6BCL2, VEGFA, CCND1, CDKN1A, BCL2L1
20gefitinib46 52 1210.5CCND1, IFI27, CDKN1A, BCL2L1, VEGFA
21thalidomide46 52 62 1211.4VEGFA, CCND1, B2M, IL6, BCL2L1, IL2
22retinoid468.4CCND1, IL2RB, CDKN1A, BCL2, BCL2L1, IFI27
23bortezomib46 52 1210.4BCL2, CCND1, CDKN1A, BCL2L1, VEGFA, IL6
24curcumin468.3VEGFA, CDKN1A, IL6, BCL2, BCL2L1, CCND1
25butyrate468.3IFI27, CCND1, B2M, BCL2L1, BCL2, CDKN1A
26imatinib46 52 1210.3CDKN1A, BCL2L1, BCL2, CCND1, VEGFA
27sb 20358046 629.3VEGFA, CCND1, CDKN1A, BCL2L1, BCL2, IL6
28cyclophosphamide46 52 1210.3B2M, VEGFA, IL2, BCL2, IL2RB
29quercetin46 62 25 1211.2BCL2L1, BCL2, IFI27, CCND1, IL2
30resveratrol46 62 25 1211.2BCL2L1, BCL2, IFI27, CCND1, CDKN1A, VEGFA
31mg 13246 629.2BCL2L1, BCL2, CDKN1A, VEGFA, IFI27, CCND1
32thymidine46 259.2CCND1, IL2RB, B2M, CDKN1A, IL6, IL2
3315-deoxy-delta-12,14-prostaglandin j2468.1CCND1, VEGFA, IFI27, CDKN1A, BCL2L1, IL6
34pd 98,059468.1CCND1, CDKN1A, BCL2L1, IL6, BCL2, IFI27
35paclitaxel46 52 1210.1CDKN1A, BCL2L1, VEGFA, CCND1, IFI27, BCL2
36actinomycin d468.0IL6, CDKN1A, VEGFA, BCL2L1, IL2, BCL2
37tamoxifen46 52 30 1211.0BCL2, VEGFA, CCND1, IFI27, IL2RB, CDKN1A
38thymidylate467.9CCND1, IFI27, BCL2L1, VEGFA, CDKN1A, BCL2
39doxorubicin46 52 129.8CCND1, B2M, VEGFA, CDKN1A, BCL2L1, BCL2
40paraffin467.8IFI27, CCND1, B2M, CDKN1A, BCL2L1, BCL2
41ly294002467.7IFI27, VEGFA, CCND1, IL6, BCL2, BCL2L1
42retinoic acid46 258.6CCND1, CDKN1A, BCL2L1, BCL2, IL6, IL2RB
43dexamethasone46 52 30 1210.6BCL2, BCL2L1, IL6, IL2RB, VEGFA, IFI27
44rapamycin467.5IFI27, BCL2L1, BCL2, IL2, CCND1, VEGFA
45n acetylcysteine467.5BCL2L1, VEGFA, BCL2, IL6, IL2RB, IFI27
46cycloheximide467.4CDKN1A, BCL2L1, BCL2, IL6, IL2RB, IL2
47estrogen467.4IFI27, IL6, B2M, BCL2, VEGFA, CCND1
48cisplatin46 52 62 1210.2BCL2, CDKN1A, BCL2L1, IL2RB, VEGFA, IL2
49vegf466.8CDKN1A, IL2, BCL2L1, B2M, VEGFA, CCND1
50genistein46 30 62 3 25 1211.8BCL2, IL6, IL2RB, IL2, IFI27, BCL2L1

GO Terms for genes affiliated with Extramedullary Plasmacytoma

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17Gene Ontology
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Cellular components related to Extramedullary Plasmacytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein kinase holoenzyme complexGO:0003079.9CDKN1A, CCND1
2external side of plasma membraneGO:0098979.1IL6, IL2RB, B2M
3mitochondrial outer membraneGO:0057418.9BCL2L1, BCL2, IFI27
4extracellular regionGO:0055768.0B2M, VEGFA, IL2, IL6, IGKC
5extracellular spaceGO:0056157.9IGKC, B2M, VEGFA, IL2, IL6

Biological processes related to Extramedullary Plasmacytoma according to GeneCards/GeneDecks:

(show all 30)
idNameGO IDScoreTop Affiliating Genes
1response to organonitrogen compoundGO:01024310.1CCND1, CDKN1A
2response to iron ionGO:01003910.1CCND1, BCL2
3response to corticosteroneGO:05141210.1CCND1, CDKN1A
4positive regulation of immunoglobulin secretionGO:05102410.0IL6, IL2
5mammary gland alveolus developmentGO:06074910.0CCND1, VEGFA
6T cell differentiation in thymusGO:0330779.9BCL2, B2M
7regulation of mitochondrial membrane permeabilityGO:0469029.9BCL2L1, BCL2
8negative regulation of anoikisGO:20008119.8BCL2, BCL2L1
9negative regulation of autophagyGO:0105079.8BCL2, BCL2L1
10regulation of mitochondrial membrane potentialGO:0518819.8BCL2L1, BCL2
11negative regulation of intrinsic apoptotic signaling pathwayGO:20012439.8BCL2L1, BCL2
12release of cytochrome c from mitochondriaGO:0018369.7BCL2L1, BCL2
13positive regulation of B cell proliferationGO:0308909.7CDKN1A, BCL2, IL2
14cellular response to DNA damage stimulusGO:0069749.7CDKN1A, BCL2, CCND1
15positive regulation of intrinsic apoptotic signaling pathwayGO:20012449.7BCL2, BCL2L1
16negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:20012409.6BCL2, BCL2L1
17growthGO:0400079.6VEGFA, BCL2L1
18intrinsic apoptotic signaling pathwayGO:0971939.5CDKN1A, BCL2L1, BCL2
19extrinsic apoptotic signaling pathway in absence of ligandGO:0971929.5BCL2L1, BCL2, IL2
20neuron apoptotic processGO:0514029.5BCL2, BCL2L1
21nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayGO:0358729.5BCL2L1, BCL2
22positive regulation of peptidyl-serine phosphorylationGO:0331389.5VEGFA, IL6, BCL2
23ovarian follicle developmentGO:0015419.4VEGFA, BCL2, BCL2L1
24lactationGO:0075959.4CCND1, VEGFA
25retina homeostasisGO:0018959.2IGKC, B2M
26cytokine-mediated signaling pathwayGO:0192219.2IL6, IL2RB, IFI27, B2M
27response to drugGO:0424939.0B2M, CCND1, IL6, BCL2, CDKN1A
28positive regulation of cell proliferationGO:0082848.9VEGFA, IL2, IL6, BCL2L1
29innate immune responseGO:0450878.4IGKC, B2M, BCL2, BCL2L1, CDKN1A
30negative regulation of apoptotic processGO:0430668.0CDKN1A, BCL2L1, BCL2, IL6, IL2RB, IL2

Molecular functions related to Extramedullary Plasmacytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1BH3 domain bindingGO:0514349.5BCL2L1, BCL2
2cytokine activityGO:0051259.1IL6, IL2, VEGFA
3growth factor activityGO:0080838.8VEGFA, IL2, IL6
4identical protein bindingGO:0428028.6BCL2L1, BCL2, VEGFA, B2M

Products for genes affiliated with Extramedullary Plasmacytoma

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Sources for Extramedullary Plasmacytoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet