MCID: EXT010
MIFTS: 49

Extramedullary Plasmacytoma malady

Categories: Cancer diseases, Immune diseases, Blood diseases

Aliases & Classifications for Extramedullary Plasmacytoma

Aliases & Descriptions for Extramedullary Plasmacytoma:

Name: Extramedullary Plasmacytoma 12 14 69
Plasmacytoma, Extramedullary 12
Extraosseous Plasmacytoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3720
ICD10 33 C90.2 C90.20
NCIt 47 C4002
UMLS 69 C0278619

Summaries for Extramedullary Plasmacytoma

MalaCards based summary : Extramedullary Plasmacytoma, also known as plasmacytoma, extramedullary, is related to plasmacytoma and anaplastic plasmacytoma. An important gene associated with Extramedullary Plasmacytoma is B2M (Beta-2-Microglobulin), and among its related pathways/superpathways are Akt Signaling and Cytokine Signaling in Immune system. The drugs Dexamethasone and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include thyroid, bone and colon, and related phenotypes are cardiovascular system and cellular

Related Diseases for Extramedullary Plasmacytoma

Diseases related to Extramedullary Plasmacytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 129)
id Related Disease Score Top Affiliating Genes
1 plasmacytoma 12.1
2 anaplastic plasmacytoma 11.1
3 multiple myeloma 10.4
4 thyroiditis 10.3
5 male infertility 10.2 BCL2 CCND1
6 coloboma of eyelid 10.2 B2M BCL2
7 encephalitis 10.2 B2M MYOM2
8 verrucous carcinoma 10.2 B2M MYOM2
9 microcystic adenoma 10.2 BCL2 CCND1
10 his bundle tachycardia 10.1 BCL2 CCND1
11 childhood vagina botryoid rhabdomyosarcoma 10.1 B2M MYOM2
12 venezuelan equine encephalitis 10.1 B2M MYOM2
13 primary ciliary dyskinesia 10.1 B2M IL6
14 colorectal cancer, hereditary nonpolyposis, type 6 10.1 BCL2 IL6
15 extramedullary soft tissue plasmacytoma 10.1
16 hereditary alpha tryptasemia syndrome 10.1 B2M IL6
17 generalized atherosclerosis 10.1 IL6 MYOM2
18 bipolar i disorder 10.1 IL6 MYOM2
19 acute cor pulmonale 10.1 IL6 MYOM2
20 nodular prostate 10.1 BCL2 IL6
21 tonsillitis 10.1
22 statin toxicity 10.1 BCL2 CCND1
23 primary tubular proximal acidosis 10.1 BCL2 IL2
24 clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly 10.1 BCL2 IL2
25 dextrocardia 10.1 IL6 MYOM2
26 plummer's disease 10.1 B2M IL6
27 central nervous system origin vertigo 10.1 B2M IL2
28 laryngotracheoesophageal cleft type 2 10.1 IL2 IL6
29 inclusion conjunctivitis 10.1 B2M IL2
30 labyrinthine bilateral reactive loss 10.1 IL2 IL6
31 cerebellar liponeurocytoma 10.1 BCL2 IL2
32 st. louis encephalitis 10.1 IL2 MYOM2
33 tinea capitis 10.1 IL2 IL6
34 clostridium difficile colitis 10.1 IL2 IL6
35 lung adenoid cystic carcinoma 10.1 BCL2 CCND1
36 early yaws 10.1 B2M IL6
37 cyclosporiasis 10.1 IL2 IL6
38 myotubular myopathy, x-linked 10.1 CCND1 CDKN1A
39 cervical verrucous carcinoma 10.0 CCND1 CDKN1A
40 hepatitis 10.0 IL2 IL6
41 lymphoma 10.0
42 mediastinitis 10.0
43 endogenous depression 10.0 IL2 MYOM2
44 stickler syndrome, type v 10.0 IL2 IL6
45 orbital osteomyelitis 10.0 IL2 IL6
46 sinusitis 10.0
47 cervicitis 10.0
48 amyloidosis 10.0
49 lip cancer 10.0 B2M BCL2
50 childhood pleomorphic rhabdomyosarcoma 10.0 B2M IL6 MYOM2

Graphical network of the top 20 diseases related to Extramedullary Plasmacytoma:



Diseases related to Extramedullary Plasmacytoma

Symptoms & Phenotypes for Extramedullary Plasmacytoma

MGI Mouse Phenotypes related to Extramedullary Plasmacytoma:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.97 B2M BCL2 CCND1 CDKN1A IL2 IL6
2 cellular MP:0005384 9.95 B2M BCL2 CCND1 CDKN1A IL2 IL6
3 digestive/alimentary MP:0005381 9.93 B2M BCL2 CCND1 CDKN1A IL2 IL6
4 endocrine/exocrine gland MP:0005379 9.91 BCL2 CCND1 CDKN1A IL2 IL6 B2M
5 hematopoietic system MP:0005397 9.88 B2M BCL2 CCND1 CDKN1A IL2 IL6
6 immune system MP:0005387 9.85 CCND1 CDKN1A IL2 IL6 B2M BCL2
7 neoplasm MP:0002006 9.73 B2M BCL2 CCND1 CDKN1A IL2 IL6
8 integument MP:0010771 9.72 B2M BCL2 CCND1 CDKN1A IL6
9 reproductive system MP:0005389 9.63 B2M BCL2 CCND1 CDKN1A IL2 IL6
10 respiratory system MP:0005388 9.35 BCL2 CCND1 CDKN1A IL2 IL6
11 vision/eye MP:0005391 9.02 BCL2 CCND1 CDKN1A IL2 IL6

Drugs & Therapeutics for Extramedullary Plasmacytoma

Drugs for Extramedullary Plasmacytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 221)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2 50-02-2 5743
2
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1 23214-92-8 31703
3
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
4
Bortezomib Approved, Investigational Phase 3,Phase 2,Phase 1 179324-69-7 387447 93860
5
Ketamine Approved, Vet_approved Phase 3 6740-88-1 3821
6
Heparin Approved, Investigational Phase 3 9005-49-6 772 46507594
7
Iron Approved Phase 3,Phase 1,Phase 2 7439-89-6 23925
8
Morphine Approved, Investigational Phase 3 57-27-2 5288826
9
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
10
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 22916-47-8 4189
11
Ondansetron Approved Phase 3 99614-02-5 4595
12
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
13
Dextromethorphan Approved Phase 3 125-71-3 5360696 5362449
14
Dalteparin Approved Phase 3 9041-08-1
15
Darbepoetin alfa Approved, Investigational Phase 3,Phase 2 11096-26-7, 209810-58-2
16
Caspofungin Approved Phase 3,Phase 2 179463-17-3, 162808-62-0 468682 2826718
17
Guaifenesin Approved, Vet_approved Phase 3 93-14-1 3516
18
Ginseng Approved, Nutraceutical Phase 3 50647-08-0
19
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1 31703
20 Dexamethasone acetate Phase 3,Phase 2 1177-87-3
21 Analgesics Phase 3
22 Alkylating Agents Phase 3,Phase 2,Phase 1
23 glucocorticoids Phase 3,Phase 2,Phase 1
24
protease inhibitors Phase 3,Phase 2,Phase 1
25 Gastrointestinal Agents Phase 3,Phase 2,Phase 1
26 Neurotransmitter Agents Phase 3,Phase 2
27 HIV Protease Inhibitors Phase 3,Phase 2,Phase 1
28 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
29 Hormone Antagonists Phase 3,Phase 2,Phase 1
30 Dexamethasone 21-phosphate Phase 3,Phase 2
31 Anesthetics Phase 3
32 Hormones Phase 3,Phase 2,Phase 1
33 Anesthetics, Dissociative Phase 3
34 Anesthetics, General Phase 3
35 Anesthetics, Intravenous Phase 3
36 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
37 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
38 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
39 Excitatory Amino Acid Antagonists Phase 3
40 Excitatory Amino Acids Phase 3
41 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
42 Proteasome Inhibitors Phase 3,Phase 1
43 Antiemetics Phase 3,Phase 2,Phase 1
44 Anti-Inflammatory Agents Phase 3,Phase 2,Phase 1
45 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
46 Antirheumatic Agents Phase 3,Phase 2,Phase 1
47 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
48 BB 1101 Phase 3,Phase 2
49 Autonomic Agents Phase 3,Phase 2,Phase 1
50 Antineoplastic Agents, Hormonal Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 68)
id Name Status NCT ID Phase
1 CDD Plus Bortezomib or CDDin Relapsed or Refractory Multiple Myeloma With Extramedullary Plasmacytoma Unknown status NCT02336386 Phase 3
2 Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain Unknown status NCT01316744 Phase 3
3 Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer Completed NCT00661999 Phase 3
4 Darbepoetin Alfa Compared With Epoetin Alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer Completed NCT00070382 Phase 3
5 Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment Completed NCT00006348 Phase 3
6 Treatment for Chronic Pain in Patients With Advanced Cancer Completed NCT00003687 Phase 3
7 Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter Completed NCT00006083 Phase 3
8 St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer Completed NCT00005805 Phase 3
9 Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial Completed NCT00750009 Phase 3
10 American Ginseng in Treating Patients With Fatigue Caused by Cancer Completed NCT00719563 Phase 3
11 Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain Completed NCT00666211 Phase 3
12 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3
13 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3
14 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3
15 Beta Alethine in Treating Patients With Myeloma Unknown status NCT00006466 Phase 1, Phase 2
16 Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer Completed NCT00489203 Phase 2
17 SWOG-9239 Reduction of Immunosuppression Plus Interferon Alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant Completed NCT00002657 Phase 2
18 Epoetin Alfa or Darbepoetin Alfa in Treating Patients With Anemia Caused by Chemotherapy Completed NCT00416624 Phase 2
19 Peripheral Blood Lymphocyte Therapy to Prevent Lymphoproliferative Disorders Caused by Epstein-Barr Virus in Patients Who Have Undergone Transplantation Completed NCT00005606 Phase 2
20 Interleukin-2 Plus Interferon Alfa in Treating Adults With Metastatic Cancer Completed NCT00002504 Phase 2
21 Epoetin Alfa in Treating Patients With Anemia Who Are Undergoing Chemotherapy for Cancer Completed NCT00255749 Phase 2
22 Non-Ablative Allo HSCT For Hematologic Malignancies or SAA Completed NCT00006379 Phase 2
23 Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer Completed NCT00003406 Phase 1, Phase 2
24 Peripheral Stem Cell Transplantation in Treating Patients With Breast Cancer or Hematologic Cancer Completed NCT00006225 Phase 1, Phase 2
25 Bone Marrow Transplantation in Treating Patients With Hematologic Cancer Completed NCT00005804 Phase 2
26 Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer Completed NCT00245037 Phase 1, Phase 2
27 Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer Completed NCT00823524 Phase 1, Phase 2
28 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2
29 Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant Completed NCT00110045 Phase 2
30 Pomalidomide, Ixazomib Citrate, and Dexamethasone in Treating Patients With Previously Treated Multiple Myeloma or Plasma Cell Leukemia Recruiting NCT02547662 Phase 2
31 Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma Recruiting NCT01849783 Phase 2
32 Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow Recruiting NCT00003838 Phase 2
33 S0340 MRI and Fludeoxyglucose F18 PET in Diagnosing Solitary Plasmacytoma Terminated NCT00109889 Phase 2
34 Velcade Combined With High-Dose Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Terminated NCT00337506 Phase 2
35 Antimicrobial Solution or Saline Solution in Maintaining Catheter Patency and Preventing Catheter-Related Blood Infections in Patients With Malignancies Withdrawn NCT01101412 Phase 1, Phase 2
36 Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer Unknown status NCT00004036 Phase 1
37 Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy Completed NCT00890747 Phase 1
38 Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction Completed NCT00025415 Phase 1
39 PS-341 in Treating Patients With Advanced Cancer Completed NCT00006362 Phase 1
40 Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Therapy Completed NCT00005634 Phase 1
41 Decitabine in Treating Patients With Melanoma or Other Advanced Cancer Completed NCT00002980 Phase 1
42 Interleukin-12 Followed by Interferon Alfa in Treating Patients With Advanced Cancer Completed NCT00003451 Phase 1
43 Combination Chemotherapy in Treating Patients With Advanced Cancer Completed NCT00003331 Phase 1
44 Monoclonal Antibody Therapy in Treating Patients With Advanced Cancer Completed NCT00003082 Phase 1
45 Stem Cell Transplantation in Treating Patients With Hematologic Cancer Completed NCT00004904 Phase 1
46 Pyroxamide in Treating Patients With Advanced Cancer Completed NCT00042900 Phase 1
47 EMD 121974 in Treating Patients With Locally Advanced or Metastatic Cancer Completed NCT00004258 Phase 1
48 Bone Marrow and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer Completed NCT00004232 Phase 1
49 Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced Cancer Completed NCT00036790 Phase 1
50 Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer Recruiting NCT01137643 Phase 1

Search NIH Clinical Center for Extramedullary Plasmacytoma

Genetic Tests for Extramedullary Plasmacytoma

Anatomical Context for Extramedullary Plasmacytoma

MalaCards organs/tissues related to Extramedullary Plasmacytoma:

39
Thyroid, Bone, Colon, Breast, Pancreas, Lymph Node, Tonsil

Publications for Extramedullary Plasmacytoma

Articles related to Extramedullary Plasmacytoma:

(show top 50) (show all 510)
id Title Authors Year
1
Oral extramedullary plasmacytoma in a HIV positive patient. ( 27894848 )
2017
2
Extramedullary Plasmacytoma of the Oral Cavity in a Young Man: a Case Report. ( 27284562 )
2016
3
Atrophoderma of Pasini and Pierini associated with extramedullary plasmacytoma. ( 27443586 )
2016
4
Extramedullary Plasmacytoma Diagnosed in an HIV-Positive Patient by an Unusual Clinical Presentation. ( 27980867 )
2016
5
Retroperitoneal laparoscopic management of a solitary extramedullary plasmacytoma associated with human immunodeficiency virus infection: A case report. ( 26870281 )
2016
6
Extramedullary Plasmacytoma of the Gallbladder Detected on Fluorine 18-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography. ( 27761300 )
2016
7
Extramedullary plasmacytoma of the gingiva. ( 26887880 )
2016
8
Extramedullary Plasmacytoma of the Maxilla Simulating a Maxillary Radicular Cyst: Quick Diagnosis and Management. ( 27054435 )
2016
9
Multiple primary cutaneous plasmacytoma a decade after a nasal solitary extramedullary plasmacytoma: a puzzling case. ( 27980740 )
2016
10
Feline Respiratory Extramedullary Plasmacytoma with Lymph Node Metastasis and Intrahistiocytic Amyloid. ( 28017340 )
2016
11
Extramedullary Plasmacytoma Presenting With Acute Airway Compromise, Treated With Emergent Rigid Bronchoscopic Resection. ( 27058726 )
2016
12
Extramedullary Plasmacytoma of the Paranasal Sinuses: Combining Surgery with External Radiotherapy. ( 27066407 )
2016
13
Solitary Extramedullary Plasmacytoma of the Maxillary Sinus, Progressing to Smoldering Multiple Myeloma with Multifocal Skeletal Involvement, which Resolved Completely Following Chemotherapy Alone. ( 27408443 )
2016
14
Establishment of an innovative staging system for extramedullary plasmacytoma. ( 27717354 )
2016
15
Primary Plurifocal Extramedullary Plasmacytoma of Breast. ( 27059937 )
2016
16
Primary Extramedullary Plasmacytoma in the Gastroduodenal Canal Associated With Epstein-Barr Virus-Associated Adenocarcinoma of the Stomach: A Case Report. ( 27466321 )
2016
17
Unusual Cause of Sphenoidal Sinus Mass: Extramedullary Plasmacytoma. ( 27779089 )
2016
18
Treatment and outcomes for primary cutaneous extramedullary plasmacytoma: a case series. ( 28050154 )
2016
19
Apparent diffusion coefficient map of a case of extramedullary plasmacytoma. ( 27200157 )
2016
20
Extramedullary Plasmacytoma Mimicking Pancreatic Cancer: An Unusual Presentation. ( 27847663 )
2016
21
Endoscopic ultrasound-fine needle aspiration: A novel way to diagnose a solitary extramedullary plasmacytoma of the liver. ( 27080614 )
2016
22
Double Extramedullary Plasmacytoma of the Stomach with a Long-term Endoscopic Follow-up. ( 27980257 )
2016
23
18F-FDG PET/CT Metabolic Activity in a Patient With Solitary Extramedullary Plasmacytoma of the Lung. ( 26462042 )
2015
24
Extramedullary plasmacytoma of the small intestine. ( 25760181 )
2015
25
Extramedullary plasmacytoma mimicking colon carcinoma: an unusual presentation and review of the literature. ( 26498668 )
2015
26
The t(11;14)(q13;q32) Translocation as a Poor Prognostic Parameter for Autologous Stem Cell Transplantation in Myeloma Patients With Extramedullary Plasmacytoma. ( 25812994 )
2015
27
Solitary Extramedullary Plasmacytoma of the Orbital Apex and Dura Masquerading as Idiopathic Inflammation. ( 26226234 )
2015
28
Unusual Extramedullary Plasmacytoma: A Rare but Possible Cause of Lymphadenopathy in Chronic Lymphocytic Leukemia. ( 26236345 )
2015
29
Primary extramedullary plasmacytoma of ovary: Report of a rare neoplasm. ( 26881544 )
2015
30
Pulmonary plasmacytoma with endobronchial extension: A rare presentation of solitary extramedullary plasmacytoma: A case report and brief review of literature. ( 26881595 )
2015
31
Unusual coexistence of extramedullary plasmacytoma and nasopharyngeal carcinoma in nasopharynx. ( 26376733 )
2015
32
Extramedullary plasmacytoma of the cricoid cartilage with solitary plasmacytoma of the rib. ( 25748689 )
2015
33
A 65-year old female with synchronous HIV and Extramedullary Plasmacytoma of Maxillary sinus. ( 26499825 )
2015
34
Radioresistant Extramedullary Plasmacytoma of the Maxillary Sinus: A Case Report and review article. ( 26788481 )
2015
35
Extramedullary plasmacytoma of the gallbladder diagnosed by endoscopic ultrasound fine needle aspiration (EUS-FNA). ( 25830051 )
2015
36
Non Secretory Multiple Myeloma With Extensive Extramedullary Plasmacytoma: A Diagnostic Dilemma. ( 26528383 )
2015
37
Extramedullary plasmacytoma of the cricoid cartilage progressing to multiple myeloma: A case report. ( 25789038 )
2015
38
Extramedullary plasmacytoma: an unusual neoplasm in a HIV-positive patient. ( 26400264 )
2015
39
Effect of definitive radiotherapy on the long-term outcome in patients with solitary extramedullary plasmacytoma. ( 26450521 )
2015
40
Solitary extramedullary plasmacytoma of thoracic epidural space presenting with dorsal compressive myelopathy: A case report and review of literature. ( 26167030 )
2015
41
A rare case of extramedullary plasmacytoma arising from posterior mediastinum. ( 26905159 )
2015
42
Computed tomography findings of a solitary extramedullary plasmacytoma of the spleen: A case report and literature review. ( 25435962 )
2015
43
A frontal extramedullary plasmacytoma mimicking parafalcine meningioma. ( 25748937 )
2015
44
Sinonasal extramedullary plasmacytoma: a population-based incidence and survival analysis. ( 25951123 )
2015
45
Extramedullary plasmacytoma associated with an ectopic tooth in the nasal cavity. ( 26535832 )
2015
46
An extramedullary plasmacytoma in the testicle: A case report and review of the literature. ( 26085896 )
2015
47
Recurrent extramedullary plasmacytoma in asymptomatic multiple myeloma: a case report. ( 25880694 )
2015
48
Prognostic factors of laryngeal solitary extramedullary plasmacytoma: a case report and review of literature. ( 26045749 )
2015
49
Irradiation combined with surgery for function preservation in the treatment of extramedullary plasmacytoma of the left labia majora during pregnancy: A case report. ( 26722319 )
2015
50
Extramedullary plasmacytoma in the right pulmonary hilum. ( 26811561 )
2015

Variations for Extramedullary Plasmacytoma

Expression for Extramedullary Plasmacytoma

Search GEO for disease gene expression data for Extramedullary Plasmacytoma.

Pathways for Extramedullary Plasmacytoma

Pathways related to Extramedullary Plasmacytoma according to GeneCards Suite gene sharing:

(show all 46)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.19 BCL2 CCND1 CDKN1A IL2 IL6
2
Show member pathways
12.91 B2M BCL2 CCND1 CDKN1A IL2 IL6
3
Show member pathways
12.82 BCL2 CCND1 CDKN1A IL6
4
Show member pathways
12.66 B2M CCND1 IL2 IL6
5
Show member pathways
12.59 CCND1 CDKN1A IL2 IL6
6
Show member pathways
12.54 BCL2 CCND1 CDKN1A IL2 IL6
7 12.46 BCL2 CCND1 CDKN1A IL6
8
Show member pathways
12.41 BCL2 CCND1 CDKN1A
9
Show member pathways
12.41 BCL2 IL2 IL6
10
Show member pathways
12.37 BCL2 CDKN1A IL2 IL6
11 12.34 BCL2 CCND1 CDKN1A
12
Show member pathways
12.2 BCL2 CCND1 CDKN1A
13 12.17 CCND1 CDKN1A IL2 IL6
14
Show member pathways
12.1 BCL2 CCND1 CDKN1A
15 12.09 BCL2 CCND1 CDKN1A IL2 IL6
16 12.03 CCND1 CDKN1A IL6
17
Show member pathways
11.97 CCND1 CDKN1A IL6
18 11.95 BCL2 CCND1 CDKN1A
19
Show member pathways
11.93 CCND1 CDKN1A IL6
20 11.91 BCL2 CCND1 CDKN1A
21 11.85 CCND1 IL2 IL6
22 11.82 BCL2 CCND1 CDKN1A
23 11.78 BCL2 CDKN1A IL6
24 11.73 BCL2 CCND1 IL6
25 11.72 BCL2 CDKN1A IL6
26 11.61 CDKN1A IL2 IL6
27 11.61 BCL2 CCND1 CDKN1A IL6
28
Show member pathways
11.59 BCL2 CCND1 CDKN1A IL2 IL6
29 11.58 BCL2 CCND1 CDKN1A
30
Show member pathways
11.47 CCND1 IL2 IL6
31 11.44 BCL2 CCND1 CDKN1A
32 11.39 CCND1 CDKN1A
33 11.35 BCL2 CDKN1A
34 11.35 BCL2 CCND1 IL6
35 11.33 CCND1 CDKN1A
36 11.29 CCND1 CDKN1A IL6
37
Show member pathways
11.28 BCL2 IL2
38 11.22 CCND1 IL6
39 11.21 CCND1 IL6
40 11.18 CCND1 CDKN1A
41 11.15 IL2 IL6
42 11.07 BCL2 IL2
43 11.05 BCL2 IL2 IL6
44
Show member pathways
11 BCL2 CDKN1A
45 10.92 BCL2 IL6
46 10.73 BCL2 CCND1 CDKN1A IL2 IL6

GO Terms for Extramedullary Plasmacytoma

Cellular components related to Extramedullary Plasmacytoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cyclin-dependent protein kinase holoenzyme complex GO:0000307 8.62 CCND1 CDKN1A

Biological processes related to Extramedullary Plasmacytoma according to GeneCards Suite gene sharing:

(show all 23)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.73 BCL2 CDKN1A IL2 IL6
2 positive regulation of cell proliferation GO:0008284 9.71 BCL2 CCND1 IL2 IL6
3 humoral immune response GO:0006959 9.61 BCL2 IL6
4 cell growth GO:0016049 9.61 BCL2 IL6
5 defense response to Gram-negative bacterium GO:0050829 9.6 B2M IL6
6 animal organ regeneration GO:0031100 9.59 CCND1 CDKN1A
7 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.58 IL2 IL6
8 T cell differentiation GO:0030217 9.58 BCL2 IL2
9 response to organonitrogen compound GO:0010243 9.57 CCND1 CDKN1A
10 response to steroid hormone GO:0048545 9.56 BCL2 CCND1
11 cellular response to organic substance GO:0071310 9.55 BCL2 CCND1
12 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.54 BCL2 IL2
13 response to organic cyclic compound GO:0014070 9.54 CCND1 CDKN1A IL6
14 T cell differentiation in thymus GO:0033077 9.52 B2M BCL2
15 negative regulation of G1/S transition of mitotic cell cycle GO:2000134 9.51 BCL2 CDKN1A
16 regulation of cell cycle GO:0051726 9.5 BCL2 CCND1 CDKN1A
17 response to X-ray GO:0010165 9.49 CCND1 CDKN1A
18 response to iron ion GO:0010039 9.48 BCL2 CCND1
19 response to corticosterone GO:0051412 9.46 CCND1 CDKN1A
20 response to drug GO:0042493 9.35 B2M BCL2 CCND1 CDKN1A IL6
21 positive regulation of B cell proliferation GO:0030890 9.33 BCL2 CDKN1A IL2
22 positive regulation of immunoglobulin secretion GO:0051024 9.26 IL2 IL6
23 response to glucocorticoid GO:0051384 8.92 BCL2 CCND1 CDKN1A IL6

Molecular functions related to Extramedullary Plasmacytoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cyclin-dependent protein serine/threonine kinase activity GO:0004693 8.62 CCND1 CDKN1A

Sources for Extramedullary Plasmacytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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