MCID: EXT031
MIFTS: 24

Extraosseous Ewing's Sarcoma malady

Summaries for Extraosseous Ewing's Sarcoma

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33MalaCards
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MalaCards: Extraosseous Ewing's Sarcoma, also known as extraosseous ewing's sarcoma/peripheral primitive neuroectodermal tumor, is related to extraskeletal ewing sarcoma and extraosseous ewings sarcoma-primitive neuroepithelial tumor. An important gene associated with Extraosseous Ewing's Sarcoma is MYF6 (myogenic factor 6 (herculin)), and among its related pathways is Transcriptional misregulation in cancer. The compounds arginine and cyclic amp have been mentioned in the context of this disorder. Related mouse phenotype tumorigenesis.

Aliases & Classifications for Extraosseous Ewing's Sarcoma

Sources:
61UMLS, 8Disease Ontology, 10DISEASES, 45Novoseek, 40NCIt
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Aliases & Descriptions:

extraosseous ewing's sarcoma 8
extraosseous ewing's sarcoma/peripheral primitive neuroectodermal tumor 8
extraosseous ewings sarcoma-primitive neuroepithelial tumor 61
extraosseous ewings sarcoma 10
sarcoma extraosseous ewings 45


External Ids:

Disease Ontology8 DOID:4232
NCIt40 C27293

Related Diseases for Extraosseous Ewing's Sarcoma

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Extraosseous Ewing's Sarcoma:



Diseases related to extraosseous ewing's sarcoma

Clinical Features for Extraosseous Ewing's Sarcoma

Drugs & Therapeutics for Extraosseous Ewing's Sarcoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Extraosseous Ewing's Sarcoma

Drug clinical trials:

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Search CenterWatch for Extraosseous Ewing's Sarcoma

Genetic Tests for Extraosseous Ewing's Sarcoma

Anatomical Context for Extraosseous Ewing's Sarcoma

Animal Models for Extraosseous Ewing's Sarcoma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Extraosseous Ewing's Sarcoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.9ETV4, MYF6, EWSR1

Publications for Extraosseous Ewing's Sarcoma

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51PubMed
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Articles related to Extraosseous Ewing's Sarcoma:

(show all 42)
idTitleAuthorsYear
1
Extraosseous Ewing's sarcoma arising in the perineal region (Rectovaginal Septum): A case report with respect to the usefulness of cytological examination. (24106051)
2013
2
An Unusual Location of Extraosseous Ewing's Sarcoma. (23898272)
2013
3
A rare case of extraosseous Ewing sarcoma primarily arising in the ovary. (24286435)
2013
4
Primary intradural extraosseous Ewing's sarcoma of the lumbar spine presenting with acute bleeding. (23472623)
2013
5
Extraosseous Ewing sarcoma and peripheral primitive neuroectodermal tumor of the thyroid gland: Case report and review. (23599116)
2013
6
Extraosseous Ewing's sarcoma of the pancreas. (21892669)
2012
7
Metastatic extraosseous Ewing's sarcoma (EES)/primitive neuroectodermal tumor (PNET) of the kidney: 8-year durable response after induction and maintenance chemotherapy. (22503609)
2012
8
Radiology-pathology conference: primary perinephric and renal extraosseous Ewing's sarcoma. (22226450)
2012
9
Spinal intradural extraosseous Ewing's sarcoma. (21464880)
2011
10
Localized extraosseous Ewing's sarcoma of the chest wall resected by video-assisted thoracoscopic surgery. (21170637)
2010
11
Extraosseous Ewing's sarcoma. (19999924)
2009
12
Primary Intradural Extraosseous Ewing's Sarcoma. (19352481)
2009
13
Extraosseous Ewing's sarcoma / primitive neuroectodermal tumor of the sacral nerve plexus. (19881073)
2009
14
Extraosseous Ewing's sarcoma: 25 years later. (18779607)
2008
15
A spontaneously ruptured primitive neuroectodermal tumor/extraosseous Ewing's sarcoma of the kidney with renal vein tumor thrombus. (17310314)
2007
16
Extraosseous Ewing's sarcoma. (17947735)
2007
17
Primary spinal epidural extraosseous Ewing's sarcoma mimicking a spinal abscess. (17786790)
2007
18
Laparoscopic removal of extraosseous Ewing's sarcoma of the kidney in a pediatric patient. (16494555)
2006
19
Primitive neurectodermal tumors: a case of extraosseous Ewing's sarcoma of the small intestine and review of the literature. (17309187)
2006
20
Protocol for the examination of specimens from pediatric and adult patients with osseous and extraosseous ewing sarcoma family of tumors, including peripheral primitive neuroectodermal tumor and ewing sarcoma. (15974809)
2005
21
Extraosseous Ewing's sarcoma of the kidney. (12187048)
2002
22
The first report of extraosseous Ewing's sarcoma in the rectovaginal septum. (12400989)
2002
23
Primary spinal epidural extraosseous Ewing's sarcoma: report of five cases and literature review. (11531770)
2001
24
Primary vulvar and vaginal extraosseous Ewing's sarcoma/peripheral neuroectodermal tumor: diagnostic confirmation with CD99 immunostaining and reverse transcriptase-polymerase chain reaction. (10782405)
2000
25
MR imaging of pancreatic metastasis from extraosseous Ewing's sarcoma. (10630390)
2000
26
A case with extraosseous Ewing's sarcoma: a late effect related to bone marrow transplantation for thalassemia or a component of a familial cancer syndrome? (10914053)
2000
27
High-dose induction chemoradiotherapy followed by autologous bone marrow transplantation as consolidation therapy in rhabdomyosarcoma, extraosseous Ewing's sarcoma, and undifferentiated sarcoma. (9586881)
1998
28
Paravertebral extraosseous Ewing's sarcoma. (10216655)
1998
29
Primary endocervical extraosseous Ewing's sarcoma/PNET. (9475198)
1998
30
Diagnostic difficulties in extraosseous Ewing's sarcoma: a proposal for diagnostic criteria. (9125062)
1997
31
A novel chimera gene between EWS and E1A-F, encoding the adenovirus E1A enhancer-binding protein, in extraosseous Ewing's sarcoma. (8605035)
1996
32
Extraosseous Ewing's sarcoma in the foot. (7550196)
1995
33
Extraosseous Ewing's sarcoma. (7704678)
1995
34
Patterns of differentiation in extraosseous Ewing's sarcoma cells. An in vitro study. (7507797)
1994
35
Primary meningeal extraosseous Ewing's sarcoma: case report. (7936137)
1994
36
Retroperitoneal extraosseous Ewing's sarcoma with renal involvement: US and MRI findings. (8348407)
1993
37
Extraosseous Ewing's sarcoma: report of a case and review of literature. (1372194)
1992
38
Primary spinal epidural extraosseous Ewing's sarcoma. (2065287)
1991
39
Extraosseous Ewing's sarcoma. A study of 42 cases. (2776115)
1989
40
Extraosseous Ewing's sarcoma. Computed tomography evaluation before and after chemotherapy. (2766077)
1989
41
Pathologic features of extraosseous Ewing's sarcoma: a report from the Intergroup Rhabdomyosarcoma Study. (3284809)
1988
42
Extraosseous Ewing's sarcoma versus primitive rhabdomyosarcoma: diagnostic criteria and clinical correlation. (3759073)
1986

Genetic Variations for Extraosseous Ewing's Sarcoma

Expression for genes affiliated with Extraosseous Ewing's Sarcoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Extraosseous Ewing's Sarcoma

Search GEO for disease gene expression data for Extraosseous Ewing's Sarcoma.

Pathways for genes affiliated with Extraosseous Ewing's Sarcoma

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30KEGG
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Pathways related to Extraosseous Ewing's Sarcoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3ETV4, EWSR1

Compounds for genes affiliated with Extraosseous Ewing's Sarcoma

Sources:
45Novoseek, 24HMDB
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Compounds related to Extraosseous Ewing's Sarcoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1arginine458.8S100B, EWSR1, ETV4
2cyclic amp45 249.7S100B, EWSR1, ETV4
3paraffin458.5S100B, EWSR1, CD99
4vegf458.3S100B, ETV4, CD99

GO Terms for genes affiliated with Extraosseous Ewing's Sarcoma

Products for genes affiliated with Extraosseous Ewing's Sarcoma

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Sources for Extraosseous Ewing's Sarcoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet