EOE
MCID: EXT052
MIFTS: 30

Extraskeletal Ewing Sarcoma (EOE) malady

Cancer diseases, Rare diseases categories
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Summaries for Extraskeletal Ewing Sarcoma

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MalaCards based summary: Extraskeletal Ewing Sarcoma, also known as EOE, is related to sarcoma and neuroectodermal tumor. An important gene associated with Extraskeletal Ewing Sarcoma is SMARCA5 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5), and among its related pathways is Transcriptional misregulation in cancer. Affiliated tissues include thyroid and breast, and related mouse phenotypes are tumorigenesis and hematopoietic system.

Aliases & Classifications for Extraskeletal Ewing Sarcoma

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Extraskeletal Ewing Sarcoma, Aliases & Descriptions:

Name: Extraskeletal Ewing Sarcoma 48
Eoe 48 62
Extraskeletal Ewing's Sarcoma 62
Extra-Osseous Ewing's Sarcoma 62
 
Extraosseous Ewing Sarcoma 48
Extraosseous Ewing's Tumor 62
Extraskeletal Ewing Tumor 48
Extraosseous Ewing Tumor 48


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Orphanet: 48 
Rare tumors


Related Diseases for Extraskeletal Ewing Sarcoma

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Graphical network of diseases related to Extraskeletal Ewing Sarcoma:



Diseases related to extraskeletal ewing sarcoma

Symptoms for Extraskeletal Ewing Sarcoma

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Drugs & Therapeutics for Extraskeletal Ewing Sarcoma

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Drug clinical trials:

Search ClinicalTrials for Extraskeletal Ewing Sarcoma

Search NIH Clinical Center for Extraskeletal Ewing Sarcoma

Genetic Tests for Extraskeletal Ewing Sarcoma

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Anatomical Context for Extraskeletal Ewing Sarcoma

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MalaCards organs/tissues related to Extraskeletal Ewing Sarcoma:

32
Thyroid, Breast

Animal Models for Extraskeletal Ewing Sarcoma or affiliated genes

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MGI Mouse Phenotypes related to Extraskeletal Ewing Sarcoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.8EWSR1, SMARCA5, FLI1
2MP:00053978.5ERG, FLI1, EWSR1
3MP:00053808.3ERG, FLI1, SMARCA5
4MP:00107687.9ERG, EWSR1, SMARCA5, FLI1

Publications for Extraskeletal Ewing Sarcoma

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Articles related to Extraskeletal Ewing Sarcoma:

(show all 20)
idTitleAuthorsYear
1
An unusual tumor of the breast - extraskeletal ewing sarcoma. (24791212)
2014
2
Multimodality imaging features, metastatic pattern and clinical outcome in adult extraskeletal Ewing sarcoma: experience in 26 patients. (24734938)
2014
3
Retraction note to: CT and MR findings in a neuroforaminal extraskeletal Ewing sarcoma mimicking benign nerve sheath tumor. Ir J Med Sci (2012) 181:123-5. (24136179)
2013
4
Extraskeletal Ewing sarcoma in children and adolescents: impact of narrow but negative surgical margin. (23982393)
2013
5
Primary extraskeletal Ewing sarcoma involving the carotid artery: a case report and review of the current literature. (22613280)
2012
6
Primary metastasized extraskeletal Ewing sarcoma of the vulva: report of a case and review of the literature. (21805144)
2012
7
CT and MR findings in a neuroforaminal extraskeletal Ewing sarcoma mimicking benign nerve sheath tumor. (20676795)
2012
8
Extraskeletal Ewing sarcoma of the mesocolon in a child. (22974628)
2012
9
Requesting clarifications concerning the case report on 'extraskeletal Ewing sarcoma of the sinonasal tract. (23361294)
2012
10
A novel t(4;22)(q31;q12) produces an EWSR1-SMARCA5 fusion in extraskeletal Ewing sarcoma/primitive neuroectodermal tumor. (21113140)
2011
11
A to Z of extraskeletal Ewing sarcoma family of tumors in adults: imaging features of primary disease, metastatic patterns, and treatment responses. (22109315)
2011
12
Clinical features and outcomes in patients with extraskeletal Ewing sarcoma. (21692057)
2011
13
A case of extraskeletal Ewing sarcoma originating from the visceral pleura. (24391423)
2011
14
Extraskeletal Ewing sarcoma of the abdominal wall. (18818133)
2008
15
Image of the month--quiz case. Retroperitoneal extraskeletal Ewing sarcoma. (18490564)
2008
16
Radiological findings of atypical extraskeletal Ewing sarcoma. (18569849)
2008
17
Spinal epidural extraskeletal Ewing sarcoma. (17316801)
2007
18
Spinal epidural extraskeletal Ewing sarcoma in an adolescent boy: a case report. (16517542)
2006
19
Extraskeletal Ewing sarcoma mimicking a thyroid nodule. (17042696)
2006
20
Primitive neuroectodermal tumor and extraskeletal Ewing sarcoma arising primarily around the spinal column: report of four cases and a review of the literature. (14520055)
2003

Variations for Extraskeletal Ewing Sarcoma

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Expression for genes affiliated with Extraskeletal Ewing Sarcoma

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Expression patterns in normal tissues for genes affiliated with Extraskeletal Ewing Sarcoma

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Pathways for genes affiliated with Extraskeletal Ewing Sarcoma

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Pathways related to Extraskeletal Ewing Sarcoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
18.5ERG, FLI1, EWSR1

Compounds for genes affiliated with Extraskeletal Ewing Sarcoma

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GO Terms for genes affiliated with Extraskeletal Ewing Sarcoma

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Cellular components related to Extraskeletal Ewing Sarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleusGO:0056348.0ERG, FLI1, SMARCA5, EWSR1

Biological processes related to Extraskeletal Ewing Sarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription from RNA polymerase II promoterGO:0063669.1ERG, FLI1
2cell differentiationGO:0301548.8ERG, FLI1
3regulation of transcription from RNA polymerase II promoterGO:0063578.5ERG, FLI1, SMARCA5

Molecular functions related to Extraskeletal Ewing Sarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1sequence-specific DNA binding RNA polymerase II transcription factor activityGO:0009818.8ERG, FLI1
2DNA bindingGO:0036778.6ERG, FLI1, SMARCA5

Products for genes affiliated with Extraskeletal Ewing Sarcoma

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Sources for Extraskeletal Ewing Sarcoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet