MCID: EXT052
MIFTS: 26

Extraskeletal Ewing Sarcoma malady

Cancer diseases, Rare diseases, Neuronal diseases categories

Summaries for Extraskeletal Ewing Sarcoma

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MalaCards based summary: Extraskeletal Ewing Sarcoma, also known as extraosseous ewings sarcoma-primitive neuroepithelial tumor, is related to sarcoma and ewing sarcoma. An important gene associated with Extraskeletal Ewing Sarcoma is SMARCA5 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5), and among its related pathways is Transcriptional misregulation in cancer. Affiliated tissues include thyroid and breast, and related mouse phenotypes are tumorigenesis and hematopoietic system.

Aliases & Classifications for Extraskeletal Ewing Sarcoma

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Extraskeletal Ewing Sarcoma, Aliases & Descriptions:

Name: Extraskeletal Ewing Sarcoma 47
Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor 60
Extraosseous Ewing Sarcoma 47
 
Extraskeletal Ewing Tumor 47
Extraosseous Ewing Tumor 47
Eoe 47


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Neuronal diseases
Orphanet: 47 
Rare tumors


External Ids:

Orphanet47 370334

Related Diseases for Extraskeletal Ewing Sarcoma

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Graphical network of diseases related to Extraskeletal Ewing Sarcoma:



Diseases related to extraskeletal ewing sarcoma

Symptoms for Extraskeletal Ewing Sarcoma

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Drugs & Therapeutics for Extraskeletal Ewing Sarcoma

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Drug clinical trials:

Search ClinicalTrials for Extraskeletal Ewing Sarcoma

Search NIH Clinical Center for Extraskeletal Ewing Sarcoma

Genetic Tests for Extraskeletal Ewing Sarcoma

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Anatomical Context for Extraskeletal Ewing Sarcoma

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MalaCards organs/tissues related to Extraskeletal Ewing Sarcoma:

31
Thyroid, Breast

Animal Models for Extraskeletal Ewing Sarcoma or affiliated genes

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MGI Mouse Phenotypes related to Extraskeletal Ewing Sarcoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.8FLI1, SMARCA5, EWSR1
2MP:00053978.5ERG, FLI1, EWSR1
3MP:00053808.3ERG, FLI1, SMARCA5
4MP:00107687.9EWSR1, SMARCA5, FLI1, ERG

Publications for Extraskeletal Ewing Sarcoma

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Articles related to Extraskeletal Ewing Sarcoma:

(show all 22)
idTitleAuthorsYear
1
Primary spinal intradural extraskeletal Ewing sarcoma mimicking a giant nerve sheath tumor: case report and review of the literature. (25674292)
2014
2
An unusual tumor of the breast - extraskeletal ewing sarcoma. (24791212)
2014
3
Multimodality imaging features, metastatic pattern and clinical outcome in adult extraskeletal Ewing sarcoma: experience in 26 patients. (24734938)
2014
4
Retraction note to: CT and MR findings in a neuroforaminal extraskeletal Ewing sarcoma mimicking benign nerve sheath tumor. Ir J Med Sci (2012) 181:123-5. (24136179)
2013
5
Extraskeletal Ewing sarcoma in children and adolescents: impact of narrow but negative surgical margin. (23982393)
2013
6
Primary extraskeletal Ewing sarcoma involving the carotid artery: a case report and review of the current literature. (22613280)
2012
7
Primary metastasized extraskeletal Ewing sarcoma of the vulva: report of a case and review of the literature. (21805144)
2012
8
CT and MR findings in a neuroforaminal extraskeletal Ewing sarcoma mimicking benign nerve sheath tumor. (20676795)
2012
9
Extraskeletal Ewing sarcoma of the mesocolon in a child. (22974628)
2012
10
Metastatic renal extraskeletal Ewing sarcoma in complete remission for the last 8 years. (20535010)
2012
11
Requesting clarifications concerning the case report on 'extraskeletal Ewing sarcoma of the sinonasal tract. (23361294)
2012
12
A novel t(4;22)(q31;q12) produces an EWSR1-SMARCA5 fusion in extraskeletal Ewing sarcoma/primitive neuroectodermal tumor. (21113140)
2011
13
A to Z of extraskeletal Ewing sarcoma family of tumors in adults: imaging features of primary disease, metastatic patterns, and treatment responses. (22109315)
2011
14
Clinical features and outcomes in patients with extraskeletal Ewing sarcoma. (21692057)
2011
15
A case of extraskeletal Ewing sarcoma originating from the visceral pleura. (24391423)
2011
16
Extraskeletal Ewing sarcoma of the abdominal wall. (18818133)
2008
17
Image of the month--quiz case. Retroperitoneal extraskeletal Ewing sarcoma. (18490564)
2008
18
Radiological findings of atypical extraskeletal Ewing sarcoma. (18569849)
2008
19
Spinal epidural extraskeletal Ewing sarcoma. (17316801)
2007
20
Spinal epidural extraskeletal Ewing sarcoma in an adolescent boy: a case report. (16517542)
2006
21
Extraskeletal Ewing sarcoma mimicking a thyroid nodule. (17042696)
2006
22
Primitive neuroectodermal tumor and extraskeletal Ewing sarcoma arising primarily around the spinal column: report of four cases and a review of the literature. (14520055)
2003

Variations for Extraskeletal Ewing Sarcoma

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Expression for genes affiliated with Extraskeletal Ewing Sarcoma

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Search GEO for disease gene expression data for Extraskeletal Ewing Sarcoma.

Pathways for genes affiliated with Extraskeletal Ewing Sarcoma

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Pathways related to Extraskeletal Ewing Sarcoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
18.5ERG, FLI1, EWSR1

Compounds for genes affiliated with Extraskeletal Ewing Sarcoma

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GO Terms for genes affiliated with Extraskeletal Ewing Sarcoma

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Cellular components related to Extraskeletal Ewing Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nucleusGO:00056348.0ERG, FLI1, SMARCA5, EWSR1

Biological processes related to Extraskeletal Ewing Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcription from RNA polymerase II promoterGO:00063669.1ERG, FLI1
2cell differentiationGO:00301548.8ERG, FLI1
3regulation of transcription from RNA polymerase II promoterGO:00063578.5ERG, FLI1, SMARCA5

Molecular functions related to Extraskeletal Ewing Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1sequence-specific DNA binding RNA polymerase II transcription factor activityGO:00009818.8ERG, FLI1
2DNA bindingGO:00036778.6ERG, FLI1, SMARCA5

Products for genes affiliated with Extraskeletal Ewing Sarcoma

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Sources for Extraskeletal Ewing Sarcoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet