HP
MCID: EXT034
MIFTS: 55

Extrinsic Allergic Alveolitis (HP) malady

Categories: Rare diseases, Respiratory diseases, Immune diseases

Aliases & Classifications for Extrinsic Allergic Alveolitis

Aliases & Descriptions for Extrinsic Allergic Alveolitis:

Name: Extrinsic Allergic Alveolitis 12 14 69
Alveolitis 12 52 14 69
Alveolitis, Extrinsic Allergic 50 42
Hypersensitivity Pneumonitis 12 50
Extrinsic Allergic Pneumonia Hypersensitivity Pneumonitis 50
Allergic Interstitial Pneumonitis 50
Pneumonitis Hypersensitivity 52
Allergic Pneumonitis 50
Hp 50

Classifications:



External Ids:

Disease Ontology 12 DOID:841
ICD10 33 J67.9 J67 J67.8
ICD9CM 35 495 495.9
MeSH 42 D000542
NCIt 47 C34369
UMLS 69 C0002390

Summaries for Extrinsic Allergic Alveolitis

Disease Ontology : 12 An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. Symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss.

MalaCards based summary : Extrinsic Allergic Alveolitis, also known as alveolitis, is related to pulmonary tuberculosis and glucosephosphate dehydrogenase deficiency, and has symptoms including hemoptysis An important gene associated with Extrinsic Allergic Alveolitis is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Omeprazole and Ciprofloxacin have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and monocytes, and related phenotypes are hematopoietic system and homeostasis/metabolism

Related Diseases for Extrinsic Allergic Alveolitis

Diseases related to Extrinsic Allergic Alveolitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 352)
id Related Disease Score Top Affiliating Genes
1 pulmonary tuberculosis 31.9 CCL5 CXCL8 IL10 IL6
2 glucosephosphate dehydrogenase deficiency 31.6 ALB IL1B IL6
3 dysentery 31.5 CD79A MPO PI3
4 parasitic protozoa infectious disease 31.0 CXCL8 CXCR3 IL10 IL1B IL6
5 asbestosis 30.1 ALB CXCL8 IL10 IL6
6 allergic bronchopulmonary aspergillosis 30.0 ALB CCL2 CXCL8 IL6
7 tuberculosis 29.8 CCL2 IL10 IL1B IL6
8 hypersensitivity pneumonitis, familial 12.1
9 hantavirus pulmonary syndrome 11.9
10 house allergic alveolitis 11.8
11 pancreatitis, hereditary 11.5
12 hermansky-pudlak syndrome 2 11.5
13 bird fancier's lung 11.5
14 farmer's lung 11.5
15 hermansky-pudlak syndrome 1 11.4
16 hermansky-pudlak syndrome 11.4
17 malaria 11.3
18 hermansky-pudlak syndrome 3 11.3
19 hermansky-pudlak syndrome 7 11.3
20 hermansky-pudlak syndrome 6 11.3
21 hermansky-pudlak syndrome 5 11.3
22 hermansky-pudlak syndrome 9 11.3
23 hermansky-pudlak syndrome 8 11.3
24 hermansky-pudlak syndrome 4 11.3
25 trypanosomiasis 11.2
26 ventilation pneumonitis 11.1
27 bagassosis 11.1
28 malt worker's lung 11.1
29 mushroom workers' lung 11.1
30 sick building syndrome 11.1
31 cork-handlers' disease 11.1
32 anhaptoglobinemia 11.0
33 coronary artery disease 10.9
34 plasmodium falciparum malaria 10.9
35 favism 10.9
36 hemochromatosis 10.9
37 crohn's disease 10.9
38 hemolytic anemia 10.9
39 paroxysmal nocturnal hemoglobinuria 10.9
40 artery disease 10.9
41 hellp syndrome 10.9
42 hemoglobinuria 10.9
43 congenital disorder of glycosylation, type in 10.8
44 ceroid lipofuscinosis, neuronal, 3 10.8
45 scurvy 10.8
46 mastitis 10.8
47 methemoglobinemia 10.8
48 bronchopneumonia 10.8
49 guillain-barre syndrome 10.8
50 megaloblastic anemia 10.8

Comorbidity relations with Extrinsic Allergic Alveolitis via Phenotypic Disease Network (PDN):


Heart Disease Postinflammatory Pulmonary Fibrosis

Graphical network of the top 20 diseases related to Extrinsic Allergic Alveolitis:



Diseases related to Extrinsic Allergic Alveolitis

Symptoms & Phenotypes for Extrinsic Allergic Alveolitis

UMLS symptoms related to Extrinsic Allergic Alveolitis:


hemoptysis

MGI Mouse Phenotypes related to Extrinsic Allergic Alveolitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10 SOD2 CXCR3 FCER2 IL10 IL1B IL2RA
2 homeostasis/metabolism MP:0005376 9.9 SOD2 CXCR3 FCER2 IL10 IL1B IL2RA
3 immune system MP:0005387 9.73 FCER2 IL10 IL1B IL2RA IL6 CCL2
4 neoplasm MP:0002006 9.17 SOD2 CXCR3 IL10 IL1B ALB IL6

Drugs & Therapeutics for Extrinsic Allergic Alveolitis

Drugs for Extrinsic Allergic Alveolitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 307)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 1 73590-58-6 4594
2
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
3
Tetracycline Approved, Vet_approved Phase 4,Phase 1 60-54-8 5353990
4
Ipratropium Approved Phase 4 22254-24-6, 60205-81-4 43232
5
Budesonide Approved Phase 4 51333-22-3 63006 5281004
6
Azithromycin Approved Phase 4,Phase 3,Phase 2 83905-01-5 55185 53477736 447043
7
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2 26787-78-0 33613 2171
8
Vancomycin Approved Phase 4 1404-90-6 441141 14969
9
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
10
Metronidazole Approved Phase 4 443-48-1 4173
11
Imipenem Approved Phase 4 74431-23-5 104838
12
Cefotaxime Approved Phase 4,Phase 2 63527-52-6 456256 5742673
13
Cefoxitin Approved Phase 4,Phase 2 35607-66-0 441199
14
Colistin Approved Phase 4,Phase 1 1264-72-8, 1066-17-7 5311054
15
Lymecycline Approved Phase 4 992-21-2 5280963
16
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
17
Zinc Approved Phase 4,Phase 3 7440-66-6 32051 23994
18
Ceftriaxone Approved Phase 4,Phase 3 73384-59-5 5479530 5361919
19
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
20
Oseltamivir Approved Phase 4 204255-11-8, 196618-13-0 65028
21
Sulfamethoxazole Approved Phase 4,Phase 3,Phase 2,Phase 1 723-46-6 5329
22
Dapsone Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 80-08-0 2955
23
Trimethoprim Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 738-70-5 5578
24
Meropenem Approved, Investigational Phase 4,Phase 3 119478-56-7 64778 441130
25
Varenicline Approved, Investigational Phase 4 249296-44-4 5310966
26
Omalizumab Approved, Investigational Phase 4 242138-07-4
27
Mupirocin Approved, Investigational, Vet_approved Phase 4 12650-69-0 446596
28
Telithromycin Approved Phase 4,Phase 3 191114-48-4 5462516
29
Cefuroxime Approved Phase 4 55268-75-2 5361202 5479529
30
Oxacillin Approved Phase 4 66-79-5 6196
31
Fluconazole Approved Phase 4 86386-73-4 3365
32
Cefdinir Approved Phase 4 91832-40-5 6915944
33
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757 53477783
34
Norgestimate Approved Phase 4 35189-28-7 6540478
35
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
36
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
37
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
38
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 58-05-9 54575, 6560146 143
39
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 59-30-3 6037
40 mometasone furoate Phase 4 83919-23-7
41 Clavulanic Acid Phase 4,Phase 2
42
Salmeterol xinafoate Phase 4 94749-08-3 56801
43 Tiotropium Bromide Phase 4 136310-93-5
44
Fluticasone Phase 4,Phase 3,Phase 2 90566-53-3, 80474-14-2 62924 22833648
45 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1
46 Fluticasone Propionate, Salmeterol Xinafoate Drug Combination Phase 4
47 Adrenergic Agents Phase 4
48 Formoterol Fumarate Phase 4
49 Adrenergic Agonists Phase 4
50 Adrenergic beta-2 Receptor Agonists Phase 4

Interventional clinical trials:

(show top 50) (show all 254)
id Name Status NCT ID Phase
1 SDD for Eradicating CRKP Carriage Unknown status NCT01761487 Phase 4
2 Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD) Unknown status NCT01822106 Phase 4
3 Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis Unknown status NCT01820026 Phase 4
4 Diverticulitis: Antibiotics or Close Observation? Unknown status NCT01111253 Phase 4
5 Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma Unknown status NCT00576069 Phase 4
6 Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced Unknown status NCT01661985 Phase 4
7 Comparison Between Amoxycillin/Clavulanic Acid and Oxacillin/Ceftriaxone for Community Acquired-pneumonia Completed NCT01166932 Phase 4
8 Gradual Initiation of Sulfamethoxazole/Trimethoprim as Primary Pneumocystis Carinii Pneumonia Prophylaxis Completed NCT00000816 Phase 4
9 The Population Pharmacokinetics of Imipenem in Patients With Ventilator-associated Pneumonia Completed NCT01489124 Phase 4
10 The Pharmacodynamics of Meropenem in Patient With Ventilator-associated Pneumonia Completed NCT02615041 Phase 4
11 The Pharmacodynamics of Doripenem Between 4-hour and 1-hour Infusion in Patients With Ventilator-associated Pneumonia Completed NCT01467648 Phase 4
12 Rapid Empiric Treatment With Oseltamivir Study (RETOS) Completed NCT01248715 Phase 4
13 PERSPECTIVE: Telithromycin - Acute Exacerbation of Chronic Bronchitis Completed NCT00132938 Phase 4
14 Prevention of RSV Infections in Bone Marrow Transplant Recipients Completed NCT00001903 Phase 4
15 Efficacy of Omalizumab in Adults (18-60 Years of Age) With Moderate-Severe, Persistent Allergic Asthma, Despite Receiving Inhaled Corticosteroids and Long Acting Beta-agonists Completed NCT00670930 Phase 4
16 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. Completed NCT01694108 Phase 4
17 Proteomic Profiling for Influenza Completed NCT00133588 Phase 4
18 Smoking Cessation Intervention in Respiratory Inpatients Completed NCT02922387 Phase 4
19 Mupirocin Ointment to Eliminate Nasal Carriage of Staphylococcus Aureus in HIV Infection Completed NCT00801879 Phase 4
20 The Effect of Prasugrel on Bronchial Hyperreactivity and on Markers of Inflammation in Patients With Chronic Asthma Completed NCT01305369 Phase 4
21 Acute Otitis Media (AOM) Therapy Trial in Young Children Completed NCT00377260 Phase 4
22 Exubera Large Simple Trial To Evaluate Long-Term Pulmonary And Cardiovascular Safety Completed NCT00359801 Phase 4
23 AZithromycin Against pLacebo in Exacerbations of Asthma Completed NCT01444469 Phase 4
24 Partnership for Rapid Elimination of Trachoma Completed NCT00792922 Phase 4
25 Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome Recruiting NCT02550080 Phase 4
26 Early Fluconazole Treatment for Coccidiodomycosis Pneumonia Recruiting NCT02663674 Phase 4
27 Trial to Evaluate Beta-Lactam Antimicrobial Therapy of Community Acquired Pneumonia in Children Recruiting NCT02891915 Phase 4
28 An Imaging Study Using PET/CT to Characterize the Effect of Intravenous Reslizumab on Airway Inflammation Recruiting NCT02937168 Phase 4
29 Study to Proof the Clinical and Bacteriological Non-inferiority of Ampicillin/Amoxicillin Versus Moxifloxacin in Hospitalized Patients With Non-severe Community-acquired Pneumonia Terminated NCT00887276 Phase 4
30 Development of Tuberculosis Diagnostic Kit Unknown status NCT00311207 Phase 3
31 Indiaclen Short Course Amoxycillin Therapy for Pneumonia With Wheeze Completed NCT00407394 Phase 3
32 New Antibiotic to Treat Patients With Community-acquired Pneumonia Due to a Specific Bacteria (S. Pneumoniae Pneumonia) Completed NCT00035269 Phase 3
33 Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Completed NCT00001013 Phase 3
34 A Study of Trimetrexate With Leucovorin Rescue for AIDS Patients Who Are Refractory to Standard Therapies for Pneumocystis Carinii Pneumonia Completed NCT00000724 Phase 3
35 A Treatment Protocol for the Use of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia and Serious Intolerance to Approved Therapies Completed NCT00001016 Phase 3
36 A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDS Completed NCT00000715 Phase 3
37 Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Completed NCT00001014 Phase 3
38 A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT) Completed NCT00000727 Phase 3
39 An Open, Prospective, Multicenter Study of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia (PCP) and Serious Intolerance to Approved Therapies Completed NCT00000714 Phase 3
40 ICMR-Indiaclen Trial on Amoxycillin vs Cotrimoxazole for Non-Severe Pneumonia Completed NCT00396526 Phase 3
41 A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or Sulfonamides Completed NCT00001028 Phase 3
42 Serological Response to Antipneumococcal Vaccination and Impact on Streptococcus Pneumoniae Nasal Carriage in HIV Adults Completed NCT02123433 Phase 3
43 Role of Oral Chlorhexidine Gel in Prevention of Ventilator Associated Pneumonia Completed NCT00597688 Phase 3
44 A Randomized, Comparative, Prospective Study of Daily Trimethoprim / Sulfamethoxazole (TMS) and Thrice-Weekly TMS for Prophylaxis Against PCP in HIV-Infected Patients Completed NCT00000748 Phase 3
45 A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or Sulfonamides Completed NCT00000802 Phase 3
46 A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS Completed NCT00000640 Phase 3
47 A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients Completed NCT00000991 Phase 3
48 Potent Antiviral Therapy for Critically Ill HIV Infected Patients Admitted to Intensive Care Completed NCT00028327 Phase 3
49 A Randomized, Unblinded Trial of Zidovudine Versus ddC in the Treatment of Patients Status Post PCP Who Received Long-Term Zidovudine Therapy in Protocol ACTG 002 Completed NCT00000682 Phase 3
50 Role of Antibiotics to Reduce Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax Completed NCT01127880 Phase 2, Phase 3

Search NIH Clinical Center for Extrinsic Allergic Alveolitis

Cochrane evidence based reviews: alveolitis, extrinsic allergic

Genetic Tests for Extrinsic Allergic Alveolitis

Anatomical Context for Extrinsic Allergic Alveolitis

MalaCards organs/tissues related to Extrinsic Allergic Alveolitis:

39
Lung, Testes, Monocytes, T Cells, Neutrophil, Skin, Myeloid

Publications for Extrinsic Allergic Alveolitis

Articles related to Extrinsic Allergic Alveolitis:

(show top 50) (show all 161)
id Title Authors Year
1
Spotlight on the diagnosis of extrinsic allergic alveolitis (hypersensitivity pneumonitis). ( 25914724 )
2015
2
PAR-2, IL-4R, TGF-I^ and TNF-I+ in bronchoalveolar lavage distinguishes extrinsic allergic alveolitis from sarcoidosis. ( 25009615 )
2014
3
Influence of age on manifestation, VC and TLCO values and bronchoalveolar lavage cell counts of sarcoidosis and extrinsic allergic alveolitis: Fibrotic response as a hallmark of aging? ( 24406019 )
2014
4
Hypersensitivity pneumonitis (extrinsic allergic alveolitis): A Canadian historical perspective. ( 25299221 )
2014
5
Role of interleukin 4 and its receptor in clinical presentation of chronic extrinsic allergic alveolitis: a pilot study. ( 23721656 )
2013
6
Linear and nonlinear analysis of base lung sound in extrinsic allergic alveolitis patients in comparison to healthy subjects. ( 23591730 )
2013
7
Surfactant protein A in chronic extrinsic allergic alveolitis. ( 22654012 )
2012
8
New occupational and environmental causes of asthma and extrinsic allergic alveolitis. ( 23153603 )
2012
9
Extrinsic allergic alveolitis as an uncommon diagnostic pitfall in lung cytology. ( 21656702 )
2012
10
Acute life-threatening extrinsic allergic alveolitis in a paint controller. ( 21824996 )
2011
11
Mortality trends in asbestosis, extrinsic allergic alveolitis and sarcoidosis in England and Wales. ( 21704503 )
2011
12
Significance of specific IgG against sensitizing antigens in extrinsic allergic alveolitis: serological methods in EAA. ( 21924863 )
2011
13
Angiogenic activity of sera from extrinsic allergic alveolitis patients in relation to clinical, radiological, and functional pulmonary changes. ( 20607270 )
2010
14
Extrinsic allergic alveolitis with an atypical immune expression. ( 19280076 )
2009
15
Clinical features and prognosis in 21 patients with extrinsic allergic alveolitis. ( 20120765 )
2009
16
Extrinsic allergic alveolitis: incidence and mortality in the general population. ( 17307752 )
2007
17
Extrinsic allergic alveolitis with eosinophil infiltration induced by 1,1,1,2-tetrafluoroethane (HFC-134a): a case report. ( 17827848 )
2007
18
An unusual case of an acquired acral partial lipodystrophy (Barraquer-Simons syndrome) in a patient with extrinsic allergic alveolitis. ( 16716174 )
2006
19
Extrinsic allergic alveolitis. ( 16635083 )
2006
20
Extrinsic allergic alveolitis: comparative study of the bronchoalveolar lavage profiles and radiological presentation. ( 16954458 )
2006
21
Involvement of eicosanoids and surfactant protein D in extrinsic allergic alveolitis. ( 16319337 )
2005
22
Cockade-like structures in alveolar macrophages in extrinsic allergic alveolitis. ( 15753634 )
2005
23
Extrinsic allergic alveolitis (hypersensitivity pneumonitis) caused by Sphingobacterium spiritivorum from the water reservoir of a steam iron. ( 16145174 )
2005
24
Extrinsic allergic alveolitis caused by misting fountains. ( 15950134 )
2005
25
Production of soluble tumor necrosis factor receptors and tumor necrosis factor-alpha by alveolar macrophages in sarcoidosis and extrinsic allergic alveolitis. ( 15653992 )
2005
26
Cockade-like structures in alveolar macrophages in extrinsic allergic alveolitis - another piece in the puzzle? ( 15753631 )
2005
27
Extrinsic allergic alveolitis: inhibitory effects of pentoxifylline on cytokine production by alveolar macrophages. ( 14989392 )
2004
28
Extrinsic allergic alveolitis with IgA deficiency. ( 15689306 )
2004
29
Extrinsic allergic alveolitis in practice. ( 15114816 )
2004
30
[Preliminary study on effect of pentoxifylline in treatment of extrinsic allergic alveolitis]. ( 15061967 )
2004
31
The HRCT features of extrinsic allergic alveolitis. ( 16088561 )
2003
32
Blood myeloid and lymphoid dendritic cells reflect Th1/Th2 balance in sarcoidosis and extrinsic allergic alveolitis. ( 15314973 )
2003
33
[Biochemical characteristics of fluid and cells of bronchoalveolar washings in patients with extrinsic allergic alveolitis]. ( 12474462 )
2002
34
Extrinsic allergic alveolitis induced by the yeast Debaryomyces hansenii. ( 12449192 )
2002
35
Respiratory syndrome very similar to extrinsic allergic alveolitis due to Penicillium verrucosum in workers in a cheese factory. ( 11307594 )
2001
36
IgG antibodies typical for extrinsic allergic alveolitis--an inter-laboratory quality assessment. ( 11726311 )
2001
37
Sulfasalazine-induced extrinsic allergic alveolitis in a patient with psoriatic arthritis. ( 11726310 )
2001
38
Extrinsic allergic alveolitis from a proteolytic enzyme. ( 11345286 )
2001
39
Extrinsic allergic alveolitis caused by cabreuva wood dust. ( 11031353 )
2000
40
Extrinsic allergic alveolitis in domestic environments (Domestic allergic alveolitis) caused by mouldy tapestry ( 10756168 )
2000
41
Pet-fish food lung- a new form of extrinsic allergic alveolitis. ( 10756166 )
2000
42
A family with extrinsic allergic alveolitis caused by wild city pigeons: A case report. ( 10799626 )
2000
43
Histologically proven extrinsic allergic alveolitis with severe obstructive pulmonary emphysema ( 10756171 )
2000
44
Effects of erythromycin on experimental extrinsic allergic alveolitis. ( 10051731 )
1999
45
Mucosal immunity in extrinsic allergic alveolitis: salivary immunoglobulins and antibody against inhaled avian antigens among pigeon breeders. ( 10383597 )
1999
46
BN 52021 decreases alveolar macrophage-mediated lung injury in experimental extrinsic allergic alveolitis. ( 10704058 )
1999
47
Elevated levels of soluble TNF receptors in bronchoalveolar lavage fluid in extrinsic allergic alveolitis. ( 10469029 )
1999
48
Aerobiological analysis in a salami factory: a possible case of extrinsic allergic alveolitis by Penicillium camembertii. ( 10421864 )
1999
49
Manganese superoxide dismutase, but not CuZn superoxide dismutase, is highly expressed in the granulomas of pulmonary sarcoidosis and extrinsic allergic alveolitis. ( 9700139 )
1998
50
BN 52021 (a platelet activating factor-receptor antagonist) decreases alveolar macrophage-mediated lung injury in experimental extrinsic allergic alveolitis. ( 9705608 )
1998

Variations for Extrinsic Allergic Alveolitis

Expression for Extrinsic Allergic Alveolitis

Search GEO for disease gene expression data for Extrinsic Allergic Alveolitis.

Pathways for Extrinsic Allergic Alveolitis

Pathways related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

(show all 48)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.99 CCL2 CCL5 CD79A CXCL8 FCER2 IL10
2
Show member pathways
13.53 CCL2 CCL5 CXCL8 CXCR3 FCER2 IL10
3
Show member pathways
13.48 CCL2 CCL5 CXCL8 IL10 IL1B IL2RA
4
Show member pathways
13.35 CCL2 CCL5 CXCL8 CXCR3 IL10 IL1B
5
Show member pathways
13.3 CCL2 CCL5 CXCL8 FCER2 IL10 IL1B
6
Show member pathways
13.2 CCL2 CCL5 CXCL8 CXCR3 IL10 IL1B
7
Show member pathways
12.93 CCL2 CCL5 CXCL8 IL1B IL6
8
Show member pathways
12.82 CXCL8 IL10 IL1B IL2RA IL6
9
Show member pathways
12.8 CCL2 CCL5 CXCL8 IL10 IL1B IL6
10
Show member pathways
12.73 CCL2 CCL5 CXCL8 IL1B IL2RA IL6
11
Show member pathways
12.58 CCL2 IL10 IL1B IL6 MPO
12
Show member pathways
12.54 IL10 IL1B IL2RA IL6
13 12.41 CCL2 CCL5 CD79A IL10 IL1B IL2RA
14
Show member pathways
12.31 CCL2 CXCL8 IL1B IL6
15
Show member pathways
12.18 CXCL8 IL1B IL6 SFTPD
16 12.17 CXCL8 IL10 IL1B IL6
17
Show member pathways
12.14 CXCL8 IL10 IL1B IL6
18
Show member pathways
12.01 CCL2 CCL5 CXCL8 CXCR3
19 11.99 CCL2 CXCL8 IL1B IL6
20 11.93 CCL2 CCL5 IL1B IL6
21 11.92 CD79A IL10 IL2RA IL6 MPO
22
Show member pathways
11.9 IL10 IL1B IL6
23 11.89 CXCL8 IL1B IL6
24 11.89 CCL2 CXCL8 IL1B IL6
25 11.86 FCER2 IL1B IL2RA IL6
26 11.85 CXCL8 IL10 IL1B IL6
27
Show member pathways
11.83 ALB CCL2 CCL5 IL1B IL6 MPO
28 11.8 CXCL8 IL1B IL6
29 11.79 CCL2 CCL5 CXCL8 IL1B IL6
30 11.75 CXCR3 IL10 IL1B IL2RA
31 11.74 IL10 IL1B IL6
32 11.71 CXCL8 IL10 IL1B IL6
33 11.7 IL10 IL2RA IL6
34 11.69 CCL2 CXCL8 FCER2 IL10 IL1B IL6
35 11.68 IL10 IL2RA IL6
36
Show member pathways
11.64 CXCL8 IL1B IL6
37 11.58 CXCL8 IL1B IL6
38 11.52 CCL2 CCL5 CXCL8 IL1B IL6
39 11.37 IL10 IL1B IL6
40 11.36 IL10 IL1B IL6
41 11.36 CCL5 IL1B IL6
42 11.34 CCL2 CXCL8 IL6
43 11.34 CCL2 CXCL8 IL10 IL1B IL6
44 11.27 IL10 IL1B IL6
45 11.11 CCL2 CCL5 CXCL8 IL10 IL1B IL6
46 10.89 CCL2 IL1B MPO
47 10.87 IL1B IL6
48 10.86 CCL2 CCL5 CXCL8 FCER2 IL10 IL1B

GO Terms for Extrinsic Allergic Alveolitis

Cellular components related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 ALB CCL2 CCL5 CXCL8 IL10 IL1B
2 external side of plasma membrane GO:0009897 9.55 CD79A CXCR3 FCER2 IL2RA IL6
3 extracellular region GO:0005576 9.36 ALB CCL2 CCL5 CXCL8 FCER2 IL10

Biological processes related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

(show all 42)
id Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.98 CCL2 IL10 IL6 SOD2
2 cell surface receptor signaling pathway GO:0007166 9.95 CCL2 CD79A CXCR3 IL2RA
3 MAPK cascade GO:0000165 9.94 CCL2 CCL5 IL1B IL2RA
4 chemotaxis GO:0006935 9.88 CCL2 CCL5 CXCL8 CXCR3
5 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.85 IL10 IL1B IL6
6 cellular response to organic cyclic compound GO:0071407 9.81 CCL2 CCL5 IL1B
7 response to glucocorticoid GO:0051384 9.8 CCL2 IL10 IL6
8 cellular response to lipopolysaccharide GO:0071222 9.8 CCL2 CXCL8 IL10 IL6
9 response to mechanical stimulus GO:0009612 9.79 CCL2 IL6 MPO
10 cellular response to tumor necrosis factor GO:0071356 9.78 CCL2 CCL5 CXCL8 IL6
11 response to activity GO:0014823 9.77 CCL2 IL10 SOD2
12 aging GO:0007568 9.77 CCL2 IL10 IL6 MPO SOD2
13 cellular response to interleukin-1 GO:0071347 9.76 CCL2 CCL5 CXCL8 IL6
14 positive regulation of nitric oxide biosynthetic process GO:0045429 9.75 IL1B IL6 SOD2
15 monocyte chemotaxis GO:0002548 9.74 CCL2 CCL5 IL6
16 cellular response to estradiol stimulus GO:0071392 9.73 CCL2 IL10 IL6
17 chemokine-mediated signaling pathway GO:0070098 9.73 CCL2 CCL5 CXCL8 CXCR3
18 negative regulation of T cell proliferation GO:0042130 9.72 IL10 IL2RA SFTPD
19 protein kinase B signaling GO:0043491 9.71 CCL2 CCL5 IL1B
20 neutrophil chemotaxis GO:0030593 9.71 CCL2 CCL5 CXCL8 IL1B
21 lipopolysaccharide-mediated signaling pathway GO:0031663 9.7 CCL2 CCL5 IL1B
22 immune response GO:0006955 9.7 CCL2 CCL5 CXCL8 IL10 IL1B IL2RA
23 positive regulation of monocyte chemotaxis GO:0090026 9.69 CCL2 CCL5
24 cellular response to fibroblast growth factor stimulus GO:0044344 9.69 CCL2 CCL5 CXCL8
25 negative regulation of growth of symbiont in host GO:0044130 9.68 IL10 MPO
26 positive regulation of macrophage chemotaxis GO:0010759 9.68 CCL2 CCL5
27 cellular response to hepatocyte growth factor stimulus GO:0035729 9.68 IL10 IL6
28 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.67 CCL2 FCER2
29 removal of superoxide radicals GO:0019430 9.67 MPO SOD2
30 response to molecule of bacterial origin GO:0002237 9.66 CXCL8 IL10
31 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.66 IL10 IL1B
32 PERK-mediated unfolded protein response GO:0036499 9.65 CCL2 CXCL8
33 negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 9.65 CCL5 CXCL8
34 neutrophil activation GO:0042119 9.64 CCL5 CXCL8
35 response to yeast GO:0001878 9.61 IL6 MPO
36 regulation of vascular endothelial growth factor production GO:0010574 9.6 CCL2 IL6
37 positive regulation of T cell proliferation GO:0042102 9.56 CCL5 IL1B IL2RA IL6
38 macrophage chemotaxis GO:0048246 9.5 CCL2 CCL5 SFTPD
39 response to lipopolysaccharide GO:0032496 9.43 CCL2 IL10 IL1B IL6 MPO SOD2
40 inflammatory response GO:0006954 9.23 CCL2 CCL5 CXCL8 CXCR3 IL10 IL1B
41 negative regulation of apoptotic process GO:0043066 10.02 ALB IL10 IL6 MPO SOD2
42 negative regulation of cell proliferation GO:0008285 10 CXCL8 IL10 IL1B IL6 SOD2

Molecular functions related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.13 CCL2 CCL5 CXCL8
2 cytokine activity GO:0005125 9.1 CCL2 CCL5 CXCL8 IL10 IL1B IL6

Sources for Extrinsic Allergic Alveolitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....