MCID: EXT034
MIFTS: 64

Extrinsic Allergic Alveolitis malady

Rare diseases, Respiratory diseases, Immune diseases categories
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Summaries for Extrinsic Allergic Alveolitis

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Disease Ontology:8 An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss.

MalaCards based summary: Extrinsic Allergic Alveolitis, also known as alveolitis, is related to allergic bronchopulmonary aspergillosis and idiopathic pulmonary fibrosis. An important gene associated with Extrinsic Allergic Alveolitis is FCER2 (Fc fragment of IgE, low affinity II, receptor for (CD23)), and among its related pathways are superoxide radicals degradation and IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types. The compounds taurine chloramine and allergens have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and monocytes, and related mouse phenotypes are skeleton and digestive/alimentary.

Wikipedia:65 Hypersensitivity pneumonitis (HP; also called extrinsic allergic alveolitis, EAA) is an inflammation of... more...

Aliases & Classifications for Extrinsic Allergic Alveolitis

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Extrinsic Allergic Alveolitis, Aliases & Descriptions:

Name: Extrinsic Allergic Alveolitis 8 62
Alveolitis 8 44 62
Allergic Interstitial Pneumonitis 42 62
Hypersensitivity Pneumonitis 8 42
 
Allergic Pneumonitis 42 62
Extrinsic Allergic Pneumonia Hypersensitivity Pneumonitis 42
Alveolitis, Extrinsic Allergic 42
Pneumonitis Hypersensitivity 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Respiratory diseases, Immune diseases


External Ids:

Disease Ontology8 DOID:841
ICD9CM27 495.9, 495
NCIt39 C34369
MeSH34 D000542
ICD1025 J67, J67.8, J67.9

Related Diseases for Extrinsic Allergic Alveolitis

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Diseases related to Extrinsic Allergic Alveolitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 227)
idRelated DiseaseScoreTop Affiliating Genes
1allergic bronchopulmonary aspergillosis31.1SFTPD, IGHE
2idiopathic pulmonary fibrosis31.1IL1B, IL8, SFTPD
3sarcoidosis31.0CD14, IL1B, ICAM1, FCER2, TNF, SFTPD
4aspergillosis30.9CD79A, SFTPD
5sinusitis30.8CD79A, IGHE
6pulmonary fibrosis30.8IL1B, IL8, SOD1, MPO, SFTPD
7pulmonary sarcoidosis30.7ICAM1, TNF, SFTPD
8interstitial lung disease30.7CD79A, IL1B, TNF, SFTPD
9bronchiolitis30.6IL8, FCER2, IGHE
10pulmonary eosinophilia30.5IL8, SFTPD, IGHE
11hypertension30.4CD79A, ALB, ICAM1
12cork-handlers' disease30.4ALB, IL8, SOD2, MPO
13arthritis30.3IL1B, IL6, IL8, TNF
14adult respiratory distress syndrome30.2IL8, TNF
15eosinophilia29.9CD79A, CD14, IL8, IL10, FCER2, MPO
16asthma29.5CD79A, CD14, IL1B, IL8, IL10, ICAM1
17glomerulonephritis29.5CD79A, ALB, IL1B, ICAM1, MPO
18pneumonia29.4CD79A, IL1B, IL6, IL8, IL10, ICAM1
19tuberculosis29.3CD79A, ALB, HP, IL1B, IL10, TNF
20vasculitis29.2CD79A, CD14, ALB, ICAM1, MPO, TNF
21colitis29.1IL1B, IL6, IL8, IL10, CXCL2, MPO
22connective tissue disease28.8CD79A, ALB, IL6, IL10, ICAM1, MPO
23ulcerative colitis28.7CD79A, CD14, IL1B, IL6, IL8, IL10
24rheumatoid arthritis28.5CD79A, CD14, HP, IL1B, IL6, IL8
25atherosclerosis28.2CD14, ALB, HP, IL1B, IL6, IL8
26acute poststreptococcal glomerulonephritis10.6CD79A
27degenerative disc disease10.6IL1B
28polyarteritis nodosa10.6MPO
29familial hypersensitivity pneumonitis10.5
30urethritis10.5CD79A
31hemoglobinuria10.5HP
32strongyloidiasis10.5IGHE
33mononeuropathy10.5MPO
34amebiasis10.5CD79A
35prostatitis10.5CD79A
36brucellosis10.5CD79A
37eosinophilic gastroenteritis10.5IGHE
38pyelonephritis10.5CD79A
39muckle-wells syndrome10.5IL1B
40filariasis10.5IGHE
41methemoglobinemia10.5HP
42farmer's lung10.5
43bird fancier's lung10.5
44rheumatoid vasculitis10.4ICAM1
45chronic conjunctivitis10.4FCER2, IGHE
46hypersensitivity vasculitis10.4CD79A, MPO
47intrinsic asthma10.4FCER2, IGHE
48conjunctivitis10.4CD79A, IGHE
49immunoglobulin g deficiency10.4CD79A, IGHE
50acute monoblastic leukemia10.4CD14, MPO

Graphical network of the top 20 diseases related to Extrinsic Allergic Alveolitis:



Diseases related to extrinsic allergic alveolitis

Symptoms for Extrinsic Allergic Alveolitis

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Drugs & Therapeutics for Extrinsic Allergic Alveolitis

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Drug clinical trials:

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Genetic Tests for Extrinsic Allergic Alveolitis

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Anatomical Context for Extrinsic Allergic Alveolitis

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MalaCards organs/tissues related to Extrinsic Allergic Alveolitis:

32
Lung, Testes, Monocytes, Skin, Myeloid, Nk cells, T cells, Neutrophil

Animal Models for Extrinsic Allergic Alveolitis or affiliated genes

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MGI Mouse Phenotypes related to Extrinsic Allergic Alveolitis:

36 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.1CD14, IL1B, IL6, IL10, SOD1, TNF
2MP:00053818.0TNF, FCER2, ICAM1, IL10, IL6, ALB
3MP:00053918.0TNF, SOD2, SOD1, ICAM1, IL10, IL6
4MP:00053707.7TNF, SOD2, SOD1, IL10, IL6, HP
5MP:00020067.6TNF, SOD2, ICAM1, IL10, IL6, IL1B
6MP:00053797.5TNF, SOD1, ICAM1, IL10, IL6, ALB
7MP:00053697.4TNF, MPO, SOD2, SOD1, ICAM1, IL10
8MP:00036317.4TNF, SOD2, SOD1, ICAM1, IL10, IL6
9MP:00053857.3TNF, MPO, SOD2, SOD1, ICAM1, IL10
10MP:00053847.0TNF, FCER2, SOD2, SOD1, ICAM1, IL10
11MP:00107686.3SFTPD, TNF, MPO, FCER2, SOD2, SOD1
12MP:00053975.7CD79A, IGHE, SFTPD, TNF, MPO, FCER2
13MP:00053875.7SOD2, FCER2, MPO, TNF, SFTPD, IGHE
14MP:00053765.5SOD2, FCER2, MPO, TNF, SFTPD, IGHE

Publications for Extrinsic Allergic Alveolitis

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Articles related to Extrinsic Allergic Alveolitis:

(show top 50)    (show all 159)
idTitleAuthorsYear
1
New occupational and environmental causes of asthma and extrinsic allergic alveolitis. (23153603)
2012
2
Acute life-threatening extrinsic allergic alveolitis in a paint controller. (21824996)
2011
3
Significance of specific IgG against sensitizing antigens in extrinsic allergic alveolitis: serological methods in EAA. (21924863)
2011
4
Extrinsic allergic alveolitis: incidence and mortality in the general population. (17307752)
2007
5
Extrinsic allergic alveolitis with eosinophil infiltration induced by 1,1,1,2-tetrafluoroethane (HFC-134a): a case report. (17827848)
2007
6
An unusual case of an acquired acral partial lipodystrophy (Barraquer-Simons syndrome) in a patient with extrinsic allergic alveolitis. (16716174)
2006
7
Production of soluble tumor necrosis factor receptors and tumor necrosis factor-alpha by alveolar macrophages in sarcoidosis and extrinsic allergic alveolitis. (15653992)
2005
8
Blood myeloid and lymphoid dendritic cells reflect Th1/Th2 balance in sarcoidosis and extrinsic allergic alveolitis. (15314973)
2003
9
Extrinsic allergic alveolitis induced by the yeast Debaryomyces hansenii. (12449192)
2002
10
Biochemical characteristics of fluid and cells of bronchoalveolar washings in patients with extrinsic allergic alveolitis]. (12474462)
2002
11
IgG antibodies typical for extrinsic allergic alveolitis--an inter-laboratory quality assessment. (11726311)
2001
12
Respiratory syndrome very similar to extrinsic allergic alveolitis due to Penicillium verrucosum in workers in a cheese factory. (11307594)
2001
13
Pet-fish food lung- a new form of extrinsic allergic alveolitis. (10756166)
2000
14
Effects of erythromycin on experimental extrinsic allergic alveolitis. (10051731)
1999
15
Elevated levels of soluble TNF receptors in bronchoalveolar lavage fluid in extrinsic allergic alveolitis. (10469029)
1999
16
Aerobiological analysis in a salami factory: a possible case of extrinsic allergic alveolitis by Penicillium camembertii. (10421864)
1999
17
Paper mill workers and chronic extrinsic allergic alveolitis. (8623683)
1996
18
Extrinsic allergic alveolitis and asthma in a sawmill worker: case report and review of the literature. (8130843)
1994
19
Expression of the adhesion molecule ICAM-1 on alveolar macrophages and in serum in extrinsic allergic alveolitis. (7903468)
1993
20
Extrinsic allergic alveolitis due to exposure to esparto dust. (1506815)
1992
21
Extrinsic allergic alveolitis: problems in diagnosis and a potential use for computed tomography. (1615180)
1992
22
Extrinsic allergic alveolitis secondary to carmine. (1678130)
1991
23
High-resolution computed tomography in extrinsic allergic alveolitis. (1999081)
1991
24
Mimics of sarcoidosis. Extrinsic allergic alveolitis. (1670003)
1991
25
Clinical guidelines and indications for bronchoalveolar lavage (BAL): extrinsic allergic alveolitis. (2292296)
1990
26
Limitations of hospital discharge diagnoses for surveillance of extrinsic allergic alveolitis. (2343875)
1990
27
Reversible pulmonary arterial hypertension in a 6-year-old girl with extrinsic allergic alveolitis. (2919518)
1989
28
Current concepts on bronchoalveolar lavage cells in extrinsic allergic alveolitis. (3068746)
1988
29
Extrinsic allergic alveolitis caused by a cold water humidifier. (3660296)
1987
30
Mast cells, atypical lymphocytes, and neutrophils in bronchoalveolar lavage in extrinsic allergic alveolitis. Comparison with other interstitial lung diseases. (2432812)
1987
31
Farmers' lung and extrinsic allergic alveolitis. (3684935)
1987
32
Antibody measurement in extrinsic allergic alveolitis. (6723835)
1984
33
Sporobolomyces: a possible cause of extrinsic allergic alveolitis. (6684133)
1983
34
Pulmonary arterial hypertension in extrinsic allergic alveolitis (EAA) (7091903)
1982
35
Bronchoalveolar lavage and transbronchial lung biopsy in sarcoidosis and extrinsic allergic alveolitis. (7173351)
1982
36
Extrinsic allergic alveolitis due to milk allergy: case report and review of the literature. (7065466)
1982
37
Phospholipids and microviscosity study in broncho-alveolar lavage fluids from control subjects and from patients with extrinsic allergic alveolitis. (7285366)
1981
38
Sawmill work and extrinsic allergic alveolitis. (6937828)
1980
39
Trapped air in extrinsic allergic alveolitis. (7444185)
1980
40
Clinical and immunological studies in pulmonary extrinsic allergic alveolitis. (Watson Prize Lecture, Royal College of Physicians and Surgeons, Glasgow, 4 April 1977). (152974)
1978
41
Extrinsic allergic alveolitis from bird exposure. Studies on the immediate hypersensitivity reaction. (563307)
1977
42
Editorial: Extrinsic allergic alveolitis. (1260333)
1976
43
Immunologically mediated lung diseases. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis. (944440)
1976
44
Extrinsic allergic alveolitis in Scottish maltworkers. (1252813)
1976
45
Extrinsic allergic alveolitis. (1089312)
1975
46
Extrinsic allergic alveolitis due to rat serum proteins. (1053443)
1975
47
Extrinsic allergic alveolitis owing to hypersensitivity to chickens-significance of sputum precipitins. (4209494)
1974
48
Extrinsic allergic alveolitis. (4574409)
1973
49
A bovine disease similar to farmer's lung: extrinsic allergic alveolitis. (4252199)
1971
50
Irreversible lung damage in extrinsic allergic alveolitis from pigeon dust inhalation. (5463319)
1970

Variations for Extrinsic Allergic Alveolitis

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Expression for genes affiliated with Extrinsic Allergic Alveolitis

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Expression patterns in normal tissues for genes affiliated with Extrinsic Allergic Alveolitis

Search GEO for disease gene expression data for Extrinsic Allergic Alveolitis.

Pathways for genes affiliated with Extrinsic Allergic Alveolitis

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Pathways related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8SOD2, SOD1
29.7IL1B, IL6
3
Show member pathways
RANKL/RANK Signaling Pathway37
Apoptosis and survival APRIL and BAFF signaling60
9.6FCER2, ICAM1, IL10
49.4IGHE, FCER2, IL10
59.4IL8, IL6, IL1B
69.4IL1B, IL6, IL8
79.3SOD1, IL6, IL1B
89.3IL6, IL8, ICAM1
99.2MPO, IL8, IL6, CD14
109.1IL1B, IL6, TNF
11
Show member pathways
9.1CD14, IL6, IL8, ICAM1
12
Show member pathways
9.0IL6, IL8, SOD1, SOD2
138.9TNF, MPO, ICAM1, IL1B
14
Show member pathways
8.9CD79A, CD14, IL1B, FCER2, TNF
15
Show member pathways
8.8IL1B, IL6, IL10, TNF
16
Show member pathways
IL27-mediated signaling events37
8.8TNF, IL10, IL6, IL1B
178.7TNF, ICAM1, IL8, IL6
188.7TNF, FCER2, IL6, IL1B, CD14
198.5CD14, IL1B, IL6, IL10, TNF
208.5TNF, IL10, IL6, IL1B, CD14
21
Show member pathways
BCR signaling pathway37
TCR Signaling Pathway37
8.5TNF, IL10, IL6, IL1B, CD79A
22
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways60
Immune response IL 1 signaling pathway60
8.5TNF, IL8, IL6, IL1B, CD14
23
Show member pathways
Immune response MIF in innate immunity response60
8.5TNF, IL8, IL6, IL1B, CD14
248.5TNF, MPO, ICAM1, IL6, HP
25
Show member pathways
8.4TNF, IL10, IL8, IL6, IL1B
268.4TNF, IL10, IL8, IL6, IL1B
278.4TNF, IL10, IL8, IL6, IL1B
288.4TNF, ICAM1, IL10, IL6, IL1B
29
Show member pathways
8.4TNF, ICAM1, IL10, IL6, IL1B
308.4TNF, ICAM1, IL8, IL6, IL1B
31
Show member pathways
8.4TNF, ICAM1, IL8, IL6, IL1B
32
Show member pathways
8.3CXCL2, IL8, IL6, IL1B, CD14
33
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
8.3SFTPD, TNF, IL8, IL6, IL1B, CD14
34
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
8.3TNF, MPO, IL10, IL6, IL1B, CD14
358.2TNF, IL10, IL8, IL6, IL1B, CD14
36
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
8.2TNF, IL10, IL8, IL6, IL1B, CD14
378.2TNF, IL10, IL8, IL6, IL1B, CD14
38
Show member pathways
8.1TNF, SOD2, SOD1, IL8, IL6, IL1B
398.1TNF, ICAM1, IL10, IL8, IL6, IL1B
408.0TNF, CXCL2, IL10, IL6, IL1B
41
Show member pathways
7.9TNF, CXCL2, IL8, IL6, IL1B
427.9IL1B, IL6, ICAM1, CXCL2, TNF
437.8TNF, CXCL2, ICAM1, IL8, IL1B, CD14
447.7TNF, CXCL2, IL8, IL6, IL1B, CD14
45
Show member pathways
7.6TNF, CXCL2, IL10, IL8, IL6, IL1B
46
Show member pathways
7.6TNF, CXCL2, IL10, IL8, IL6, IL1B
47
Show member pathways
7.6TNF, CXCL2, IL10, IL8, IL6, IL1B
487.6TNF, CXCL2, ICAM1, IL8, IL6, IL1B
49
Show member pathways
thioredoxin pathway37
7.2ALB, TNF, MPO, SOD2, SOD1, ICAM1
50
Show member pathways
6.9TNF, FCER2, SOD2, CXCL2, IL10, IL8

Compounds for genes affiliated with Extrinsic Allergic Alveolitis

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Compounds related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show top 50)    (show all 303)
idCompoundScoreTop Affiliating Genes
1taurine chloramine448.8TNF, MPO, IL8, IL6, IL1B
2allergens448.8FCER2, SFTPD, IGHE, IL10, CD79A, CD14
3methacholine44 50 1110.7CD14, IL8, ICAM1, CD79A, MPO, IGHE
4mip 1alpha448.7IL10, TNF, IL8, IL6, IL1B
5okt3448.6CD79A, TNF, FCER2, ICAM1, IL6, IL10
6lipoteichoic acid448.5IL1B, CD14, IL6, IL8, IL10, TNF
75 aminosalicylic acid448.5IL8, IL10, MPO, TNF, IL1B
8sulfasalazine28 44 50 1111.5TNF, MPO, ICAM1, IL8, IL1B, HP
9triptolide448.5IL1B, ICAM1, IL8, TNF, CD14, IL6
10peptidoglycan44 289.4TNF, IL1B, CD14, IL6, IL8, IL10
11rantes448.4CXCL2, IL10, ICAM1, CD14, IL8, IL1B
12diphenyleneiodonium448.3SOD2, SOD1, ICAM1, IL8, IL1B, MPO
13gm-csf44 289.3IL6, IL1B, CD14, IL8, IL10, TNF
14polymyxin b448.2TNF, ICAM1, IL10, IL8, IL6, IL1B
15budesonide44 50 1110.2IL1B, IL8, IGHE, SFTPD, TNF, MPO
16il-12448.1TNF, IL10, IL8, IL1B, IL6
17fmlp448.1ICAM1, IL8, CD14, IL1B, FCER2, MPO
18herbimycin a44 619.0IL8, IL1B, ICAM1, FCER2, TNF, IL6
19pdtc447.9TNF, FCER2, SOD2, SOD1, ICAM1, IL8
20ascorbic acid44 248.9CD79A, HP, IGHE, ICAM1, ALB, SOD1
21ulinastatin447.9MPO, SOD1, ICAM1, IL10, IL8, IL6
22calcitriol44 61 24 1110.9CD14, IL10, SOD2, FCER2, TNF, ALB
23ivig447.9ALB, CD79A, IGHE, TNF, IL10, IL6
24hydrocortisone44 2 61 1110.9TNF, IGHE, FCER2, IL10, IL8, IL6
258-isoprostane447.9TNF, MPO, SOD1, ICAM1, IL10, IL8
26vitamin d447.8CD79A, CD14, ALB, HP, IL6, IL10
27pentoxifylline44 118.7TNF, MPO, ICAM1, IL10, IL8, IL6
28tarc447.7CXCL2, ICAM1, IL10, IL8, IGHE, TNF
29groalpha447.7TNF, CXCL2, ICAM1, IL10, IL8, IL6
30ccl344 288.6TNF, IL1B, IL6, IL10, IL8, CXCL2
31neopterin447.6TNF, FCER2, ICAM1, IL10, IL8, IL6
32creatinine447.5ALB, SOD2, MPO, SOD1, IL6, HP
33hyaluronic acid44 248.5CD79A, IL6, HP, ALB, IL1B, IL8
34methotrexate50 44 119.5IL6, SOD2, IL10, IL1B, ALB, CD79A
35prednisolone44 28 119.5IGHE, SFTPD, TNF, MPO, IL10, IL6
36sb 20358044 618.3IL1B, FCER2, CXCL2, ICAM1, IL10, TNF
37indomethacin44 28 61 1110.2IL1B, CD79A, ALB, IL6, SOD1, SOD2
38cyclosporin a44 28 619.2CD79A, IL10, IGHE, TNF, CD14, HP
39cycloheximide447.2CD14, IL6, IL8, ICAM1, SOD2, TNF
40fibrinogen447.1TNF, CXCL2, IL6, ALB, CD14, CD79A
41ly294002447.1TNF, SOD2, CD14, IL6, IL8, CXCL2
42endotoxin447.0ICAM1, IL10, IL8, IL6, IL1B, HP
43h2o2446.9CXCL2, SOD1, SOD2, MPO, TNF, IL8
44pge2446.4MPO, FCER2, CXCL2, ICAM1, IL10, IL8
45histamine44 28 248.3IGHE, SFTPD, TNF, MPO, FCER2, ICAM1
46n acetylcysteine446.3IL6, IL1B, CD79A, IL8, ICAM1, IGHE
47nitric oxide44 24 118.0HP, IL1B, ICAM1, CXCL2, SOD1, SOD2
48vegf445.8CD14, HP, IL1B, IL6, CD79A, ICAM1
49dexamethasone44 50 28 118.7SFTPD, IGHE, CD79A, TNF, FCER2, SOD2
50lactate445.1IGHE, SFTPD, TNF, MPO, FCER2, SOD2

GO Terms for genes affiliated with Extrinsic Allergic Alveolitis

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Cellular components related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1membrane raftGO:0451219.4CD79A, CD14, TNF
2external side of plasma membraneGO:0098978.5TNF, FCER2, ICAM1, IL6, CD79A
3extracellular vesicular exosomeGO:0700627.9MPO, FCER2, SOD1, ICAM1, HP, ALB
4extracellular regionGO:0055765.8IGHE, SFTPD, TNF, SOD1, CXCL2, IL8
5extracellular spaceGO:0056155.4CD14, SFTPD, TNF, MPO, SOD1, CXCL2

Biological processes related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show top 50)    (show all 52)
idNameGO IDScoreTop Affiliating Genes
1response to superoxideGO:00030310.2SOD2, SOD1
2hydrogen peroxide biosynthetic processGO:05066510.1SOD2, SOD1
3superoxide anion generationGO:04255410.0SOD2, SOD1
4positive regulation of humoral immune response mediated by circulating immunoglobulinGO:00292510.0TNF, FCER2
5defense response to bacteriumGO:04274210.0SFTPD, IL10, HP
6response to copper ionGO:04668810.0ICAM1, SOD1
7sequestering of triglycerideGO:03073010.0IL1B, TNF
8removal of superoxide radicalsGO:01943010.0SOD1, SOD2, MPO
9response to hydrogen peroxideGO:04254210.0HP, SOD1, SOD2
10positive regulation of calcidiol 1-monooxygenase activityGO:06055910.0IL1B, TNF
11positive regulation of heterotypic cell-cell adhesionGO:0341169.9TNF, IL1B
12positive regulation of fever generationGO:0316229.9TNF, IL1B
13response to electrical stimulusGO:0516029.9IL6, SOD2
14receptor biosynthetic processGO:0328009.9IL10, TNF
15negative regulation of cytokine secretion involved in immune responseGO:0027409.9TNF, IL10
16positive regulation of chemokine biosynthetic processGO:0450809.9TNF, IL1B
17superoxide metabolic processGO:0068019.9SOD1, SOD2
18regulation of I-kappaB kinase/NF-kappaB signalingGO:0431229.9IL1B, TNF
19regulation of mitochondrial membrane potentialGO:0518819.9SOD2, SOD1
20positive regulation of membrane protein ectodomain proteolysisGO:0510449.8IL1B, TNF
21negative regulation of lipid catabolic processGO:0509959.8TNF, IL1B
22response to ethanolGO:0454719.8CD14, ICAM1, SOD1
23response to heatGO:0094089.8SOD1, IL6, CD14
24epithelial cell proliferation involved in salivary gland morphogenesisGO:0606649.8TNF, IL6
25muscle cell cellular homeostasisGO:0467169.8SOD1, IL6
26negative regulation of lipid storageGO:0108889.8TNF, IL6
27positive regulation of cytokine secretionGO:0507159.7CD14, IL10, TNF
28response to lipopolysaccharideGO:0324969.7MPO, SOD2, IL6
29negative regulation of growth of symbiont in hostGO:0441309.7IL10, MPO, TNF
30embryonic digestive tract developmentGO:0485669.7TNF, IL8
31response to activityGO:0148239.7TNF, SOD2, IL10
32cellular response to lipopolysaccharideGO:0712229.6ICAM1, IL10, IL8, CD14
33positive regulation of chemokine productionGO:0327229.6IL6, TNF
34response to nutrient levelsGO:0316679.6SOD1, IL6
35negative regulation of fat cell differentiationGO:0455999.5TNF, SOD2, IL6
36response to mechanical stimulusGO:0096129.5TNF, MPO, IL6
37positive regulation of interleukin-6 productionGO:0327559.5IL1B, IL6, TNF
38activation of MAPK activityGO:0001879.5TNF, SOD1, IL1B
39response to glucocorticoidGO:0513849.4IL6, IL10, TNF
40response to molecule of bacterial originGO:0022379.4CXCL2, IL10, IL8
41positive regulation of cytokine productionGO:0018199.3TNF, SOD1
42positive regulation of NF-kappaB import into nucleusGO:0423469.3IL1B, TNF
43positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.2TNF, IL10, IL6, IL1B
44positive regulation of NF-kappaB transcription factor activityGO:0510929.2TNF, ICAM1, IL6, IL1B
45negative regulation of apoptotic processGO:0430668.9ALB, IL6, IL10, MPO
46negative regulation of cell proliferationGO:0082858.9IL1B, IL6, IL8, SOD2, TNF
47positive regulation of nitric oxide biosynthetic processGO:0454298.9IL1B, IL6, ICAM1, SOD2, TNF
48immune responseGO:0069558.8IL1B, IL8, CXCL2, IGHE
49response to drugGO:0424938.5TNF, SOD2, SOD1, ICAM1, IL10, IL6
50inflammatory responseGO:0069547.8TNF, CXCL2, IL10, IL8, IL6, IL1B

Molecular functions related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1antioxidant activityGO:0162099.7ALB, HP
2superoxide dismutase activityGO:0047849.7SOD2, SOD1
3cytokine activityGO:0051258.8IL1B, IL6, IL10, TNF
4protein bindingGO:0055155.9SFTPD, TNF, SOD1, CXCL2, ICAM1, IL8

Products for genes affiliated with Extrinsic Allergic Alveolitis

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  • Antibodies
  • Proteins
  • Lysates

Sources for Extrinsic Allergic Alveolitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet