MCID: EXT034
MIFTS: 54

Extrinsic Allergic Alveolitis malady

Rare diseases, Respiratory diseases, Immune diseases categories

Aliases & Classifications for Extrinsic Allergic Alveolitis

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Extrinsic Allergic Alveolitis, Aliases & Descriptions:

Name: Extrinsic Allergic Alveolitis 9 60
Alveolitis 9 43 60
Hypersensitivity Pneumonitis 9 41
Extrinsic Allergic Pneumonia Hypersensitivity Pneumonitis 41
 
Allergic Interstitial Pneumonitis 41
Alveolitis, Extrinsic Allergic 41
Pneumonitis Hypersensitivity 43
Allergic Pneumonitis 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Respiratory diseases, Immune diseases


External Ids:

Disease Ontology9 DOID:841
ICD9CM27 495.9, 495
MeSH33 D000542
NCIt38 C34369
ICD1025 J67, J67.8, J67.9

Summaries for Extrinsic Allergic Alveolitis

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Disease Ontology:9 An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss.

MalaCards based summary: Extrinsic Allergic Alveolitis, also known as alveolitis, is related to allergic bronchopulmonary aspergillosis and pulmonary fibrosis, idiopathic. An important gene associated with Extrinsic Allergic Alveolitis is FCER2 (Fc fragment of IgE, low affinity II, receptor for (CD23)), and among its related pathways are superoxide radicals degradation and IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types. The compounds taurine chloramine and allergens have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and monocytes, and related mouse phenotypes are skeleton and digestive/alimentary.

Related Diseases for Extrinsic Allergic Alveolitis

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Diseases related to Extrinsic Allergic Alveolitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 220)
idRelated DiseaseScoreTop Affiliating Genes
1allergic bronchopulmonary aspergillosis31.1SFTPD, IGHE
2pulmonary fibrosis, idiopathic30.9IL1B, IL8, SFTPD
3aspergillosis30.9CD79A, SFTPD
4sinusitis30.8CD79A, IGHE
5pulmonary fibrosis30.8IL1B, IL8, SOD1, MPO, SFTPD
6pulmonary sarcoidosis30.7ICAM1, TNF, SFTPD
7interstitial lung disease30.7CD79A, IL1B, TNF, SFTPD
8bronchiolitis30.6IL8, FCER2, IGHE
9pulmonary eosinophilia30.5IL8, SFTPD, IGHE
10cork-handlers' disease30.4ALB, IL8, SOD2, MPO
11arthritis30.3IL1B, IL6, IL8, TNF
12hiv-130.3CD14, HP, FCER2, SFTPD
13eosinophilia29.9CD79A, CD14, IL8, IL10, FCER2, MPO
14asthma29.5CD79A, CD14, IL1B, IL8, IL10, ICAM1
15pneumonia29.4CD79A, IL1B, IL6, IL8, IL10, ICAM1
16tuberculosis29.3CD79A, ALB, HP, IL1B, IL10, TNF
17vasculitis29.2CD79A, CD14, ALB, ICAM1, MPO, TNF
18colitis29.1IL1B, IL6, IL8, IL10, CXCL2, MPO
19connective tissue disease28.8CD79A, ALB, IL6, IL10, ICAM1, MPO
20ulcerative colitis28.7CD79A, CD14, IL1B, IL6, IL8, IL10
21rheumatoid arthritis28.5CD79A, CD14, HP, IL1B, IL6, IL8
22atherosclerosis28.2CD14, ALB, HP, IL1B, IL6, IL8
23acute poststreptococcal glomerulonephritis10.6CD79A
24intervertebral disc disease10.6IL1B
25polyarteritis nodosa10.6MPO
26urethritis10.5CD79A
27strongyloidiasis10.5IGHE
28hemoglobinuria10.5HP
29mononeuropathy10.5MPO
30amebiasis10.5CD79A
31prostatitis10.5CD79A
32brucellosis10.5CD79A
33eosinophilic gastroenteritis10.5IGHE
34pyelonephritis10.5CD79A
35muckle-wells syndrome10.5IL1B
36filariasis10.5IGHE
37methemoglobinemia10.5HP
38bird fancier's lung10.5
39farmer's lung10.5
40familial hypersensitivity pneumonitis10.5
41rheumatoid vasculitis10.4ICAM1
42chronic conjunctivitis10.4FCER2, IGHE
43hypersensitivity vasculitis10.4CD79A, MPO
44intrinsic asthma10.4FCER2, IGHE
45conjunctivitis10.4CD79A, IGHE
46immunoglobulin g deficiency10.4CD79A, IGHE
47acute monocytic leukemia10.4CD14, MPO
48selective iga deficiency disease10.4CD79A, IL10
49immunodeficiency, x-linked, with hyper-igm10.4CD79A, IGHE
50cutaneous leishmaniasis10.4IL10, FCER2

Graphical network of the top 20 diseases related to Extrinsic Allergic Alveolitis:



Diseases related to extrinsic allergic alveolitis

Symptoms for Extrinsic Allergic Alveolitis

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Drugs & Therapeutics for Extrinsic Allergic Alveolitis

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Drug clinical trials:

Search ClinicalTrials for Extrinsic Allergic Alveolitis

Search NIH Clinical Center for Extrinsic Allergic Alveolitis

Genetic Tests for Extrinsic Allergic Alveolitis

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Anatomical Context for Extrinsic Allergic Alveolitis

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MalaCards organs/tissues related to Extrinsic Allergic Alveolitis:

31
Lung, Testes, Monocytes, Skin, Myeloid, Nk cells, T cells, Neutrophil

Animal Models for Extrinsic Allergic Alveolitis or affiliated genes

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MGI Mouse Phenotypes related to Extrinsic Allergic Alveolitis:

35 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.1CD14, IL1B, IL6, IL10, SOD1, TNF
2MP:00053818.0TNF, FCER2, ICAM1, IL10, IL6, ALB
3MP:00053918.0TNF, SOD2, SOD1, ICAM1, IL10, IL6
4MP:00053707.7TNF, SOD2, SOD1, IL10, IL6, HP
5MP:00020067.6TNF, SOD2, ICAM1, IL10, IL6, IL1B
6MP:00053797.5TNF, SOD1, ICAM1, IL10, IL6, ALB
7MP:00053697.4TNF, MPO, SOD2, SOD1, ICAM1, IL10
8MP:00036317.4TNF, SOD2, SOD1, ICAM1, IL10, IL6
9MP:00053857.3TNF, MPO, SOD2, SOD1, ICAM1, IL10
10MP:00053847.0TNF, FCER2, SOD2, SOD1, ICAM1, IL10
11MP:00107686.3SFTPD, TNF, MPO, FCER2, SOD2, SOD1
12MP:00053975.7CD79A, IGHE, SFTPD, TNF, MPO, FCER2
13MP:00053875.7SOD2, FCER2, MPO, TNF, SFTPD, IGHE
14MP:00053765.5SOD2, FCER2, MPO, TNF, SFTPD, IGHE

Publications for Extrinsic Allergic Alveolitis

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Articles related to Extrinsic Allergic Alveolitis:

(show top 50)    (show all 160)
idTitleAuthorsYear
1
New occupational and environmental causes of asthma and extrinsic allergic alveolitis. (23153603)
2012
2
Acute life-threatening extrinsic allergic alveolitis in a paint controller. (21824996)
2011
3
Significance of specific IgG against sensitizing antigens in extrinsic allergic alveolitis: serological methods in EAA. (21924863)
2011
4
Extrinsic allergic alveolitis: incidence and mortality in the general population. (17307752)
2007
5
Extrinsic allergic alveolitis with eosinophil infiltration induced by 1,1,1,2-tetrafluoroethane (HFC-134a): a case report. (17827848)
2007
6
An unusual case of an acquired acral partial lipodystrophy (Barraquer-Simons syndrome) in a patient with extrinsic allergic alveolitis. (16716174)
2006
7
Production of soluble tumor necrosis factor receptors and tumor necrosis factor-alpha by alveolar macrophages in sarcoidosis and extrinsic allergic alveolitis. (15653992)
2005
8
Blood myeloid and lymphoid dendritic cells reflect Th1/Th2 balance in sarcoidosis and extrinsic allergic alveolitis. (15314973)
2003
9
Extrinsic allergic alveolitis induced by the yeast Debaryomyces hansenii. (12449192)
2002
10
Biochemical characteristics of fluid and cells of bronchoalveolar washings in patients with extrinsic allergic alveolitis]. (12474462)
2002
11
IgG antibodies typical for extrinsic allergic alveolitis--an inter-laboratory quality assessment. (11726311)
2001
12
Respiratory syndrome very similar to extrinsic allergic alveolitis due to Penicillium verrucosum in workers in a cheese factory. (11307594)
2001
13
Pet-fish food lung- a new form of extrinsic allergic alveolitis. (10756166)
2000
14
Effects of erythromycin on experimental extrinsic allergic alveolitis. (10051731)
1999
15
Elevated levels of soluble TNF receptors in bronchoalveolar lavage fluid in extrinsic allergic alveolitis. (10469029)
1999
16
Aerobiological analysis in a salami factory: a possible case of extrinsic allergic alveolitis by Penicillium camembertii. (10421864)
1999
17
Paper mill workers and chronic extrinsic allergic alveolitis. (8623683)
1996
18
Extrinsic allergic alveolitis and asthma in a sawmill worker: case report and review of the literature. (8130843)
1994
19
Expression of the adhesion molecule ICAM-1 on alveolar macrophages and in serum in extrinsic allergic alveolitis. (7903468)
1993
20
Extrinsic allergic alveolitis due to exposure to esparto dust. (1506815)
1992
21
Extrinsic allergic alveolitis: problems in diagnosis and a potential use for computed tomography. (1615180)
1992
22
Extrinsic allergic alveolitis secondary to carmine. (1678130)
1991
23
High-resolution computed tomography in extrinsic allergic alveolitis. (1999081)
1991
24
Mimics of sarcoidosis. Extrinsic allergic alveolitis. (1670003)
1991
25
Clinical guidelines and indications for bronchoalveolar lavage (BAL): extrinsic allergic alveolitis. (2292296)
1990
26
Limitations of hospital discharge diagnoses for surveillance of extrinsic allergic alveolitis. (2343875)
1990
27
Reversible pulmonary arterial hypertension in a 6-year-old girl with extrinsic allergic alveolitis. (2919518)
1989
28
Current concepts on bronchoalveolar lavage cells in extrinsic allergic alveolitis. (3068746)
1988
29
Extrinsic allergic alveolitis caused by a cold water humidifier. (3660296)
1987
30
Mast cells, atypical lymphocytes, and neutrophils in bronchoalveolar lavage in extrinsic allergic alveolitis. Comparison with other interstitial lung diseases. (2432812)
1987
31
Farmers' lung and extrinsic allergic alveolitis. (3684935)
1987
32
Antibody measurement in extrinsic allergic alveolitis. (6723835)
1984
33
Sporobolomyces: a possible cause of extrinsic allergic alveolitis. (6684133)
1983
34
Pulmonary arterial hypertension in extrinsic allergic alveolitis (EAA) (7091903)
1982
35
Bronchoalveolar lavage and transbronchial lung biopsy in sarcoidosis and extrinsic allergic alveolitis. (7173351)
1982
36
Extrinsic allergic alveolitis due to milk allergy: case report and review of the literature. (7065466)
1982
37
Phospholipids and microviscosity study in broncho-alveolar lavage fluids from control subjects and from patients with extrinsic allergic alveolitis. (7285366)
1981
38
Sawmill work and extrinsic allergic alveolitis. (6937828)
1980
39
Trapped air in extrinsic allergic alveolitis. (7444185)
1980
40
Clinical and immunological studies in pulmonary extrinsic allergic alveolitis. (Watson Prize Lecture, Royal College of Physicians and Surgeons, Glasgow, 4 April 1977). (152974)
1978
41
Extrinsic allergic alveolitis from bird exposure. Studies on the immediate hypersensitivity reaction. (563307)
1977
42
Editorial: Extrinsic allergic alveolitis. (1260333)
1976
43
Immunologically mediated lung diseases. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis. (944440)
1976
44
Extrinsic allergic alveolitis in Scottish maltworkers. (1252813)
1976
45
Extrinsic allergic alveolitis. (1089312)
1975
46
Extrinsic allergic alveolitis due to rat serum proteins. (1053443)
1975
47
Extrinsic allergic alveolitis owing to hypersensitivity to chickens-significance of sputum precipitins. (4209494)
1974
48
Extrinsic allergic alveolitis. (4574409)
1973
49
A bovine disease similar to farmer's lung: extrinsic allergic alveolitis. (4252199)
1971
50
Irreversible lung damage in extrinsic allergic alveolitis from pigeon dust inhalation. (5463319)
1970

Variations for Extrinsic Allergic Alveolitis

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Expression for genes affiliated with Extrinsic Allergic Alveolitis

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Search GEO for disease gene expression data for Extrinsic Allergic Alveolitis.

Pathways for genes affiliated with Extrinsic Allergic Alveolitis

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Pathways related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 57)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8SOD2, SOD1
29.7IL1B, IL6
3
Show member pathways
RANKL/RANK Signaling Pathway36
Apoptosis and survival APRIL and BAFF signaling58
9.6FCER2, ICAM1, IL10
49.4IGHE, FCER2, IL10
59.4IL1B, IL6, IL8
69.3SOD1, IL6, IL1B
79.3IL6, IL8, ICAM1
89.2MPO, IL8, IL6, CD14
99.1IL1B, IL6, TNF
10
Show member pathways
9.1CD14, IL6, IL8, ICAM1
11
Show member pathways
9.0IL6, IL8, SOD1, SOD2
128.9TNF, MPO, ICAM1, IL1B
13
Show member pathways
8.9CD79A, CD14, IL1B, FCER2, TNF
14
Show member pathways
8.8IL1B, IL6, IL10, TNF
15
Show member pathways
IL27-mediated signaling events36
8.8TNF, IL10, IL6, IL1B
168.7TNF, ICAM1, IL8, IL6
178.7TNF, FCER2, IL6, IL1B, CD14
188.5CD14, IL1B, IL6, IL10, TNF
198.5TNF, IL10, IL6, IL1B, CD14
20
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
8.5TNF, IL10, IL6, IL1B, CD79A
21
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways58
Immune response IL 1 signaling pathway58
8.5TNF, IL8, IL6, IL1B, CD14
22
Show member pathways
Immune response MIF in innate immunity response58
8.5TNF, IL8, IL6, IL1B, CD14
238.5TNF, MPO, ICAM1, IL6, HP
24
Show member pathways
8.4TNF, IL10, IL8, IL6, IL1B
258.4TNF, IL10, IL8, IL6, IL1B
268.4TNF, IL10, IL8, IL6, IL1B
278.4TNF, ICAM1, IL10, IL6, IL1B
28
Show member pathways
8.4TNF, ICAM1, IL10, IL6, IL1B
298.4TNF, ICAM1, IL8, IL6, IL1B
30
Show member pathways
8.4TNF, ICAM1, IL8, IL6, IL1B
31
Show member pathways
8.3CXCL2, IL8, IL6, IL1B, CD14
32
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
8.3SFTPD, TNF, IL8, IL6, IL1B, CD14
33
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
8.3TNF, MPO, IL10, IL6, IL1B, CD14
348.2TNF, IL10, IL8, IL6, IL1B, CD14
35
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
8.2TNF, IL10, IL8, IL6, IL1B, CD14
368.2TNF, IL10, IL8, IL6, IL1B, CD14
37
Show member pathways
8.1TNF, SOD2, SOD1, IL8, IL6, IL1B
388.1TNF, ICAM1, IL10, IL8, IL6, IL1B
398.0TNF, CXCL2, IL10, IL6, IL1B
40
Show member pathways
7.9TNF, CXCL2, IL8, IL6, IL1B
417.9IL1B, IL6, ICAM1, CXCL2, TNF
427.8TNF, CXCL2, ICAM1, IL8, IL1B, CD14
437.7TNF, CXCL2, IL8, IL6, IL1B, CD14
44
Show member pathways
7.6TNF, CXCL2, IL10, IL8, IL6, IL1B
45
Show member pathways
7.6TNF, CXCL2, IL10, IL8, IL6, IL1B
46
Show member pathways
7.6TNF, CXCL2, IL10, IL8, IL6, IL1B
477.6TNF, CXCL2, ICAM1, IL8, IL6, IL1B
48
Show member pathways
thioredoxin pathway36
7.2ALB, TNF, MPO, SOD2, SOD1, ICAM1
49
Show member pathways
6.9TNF, FCER2, SOD2, CXCL2, IL10, IL8

Compounds for genes affiliated with Extrinsic Allergic Alveolitis

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Compounds related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 303)
idCompoundScoreTop Affiliating Genes
1taurine chloramine438.8TNF, MPO, IL8, IL6, IL1B
2allergens438.8FCER2, SFTPD, IGHE, IL10, CD79A, CD14
3methacholine43 49 1210.7CD14, IL8, ICAM1, CD79A, MPO, IGHE
4mip 1alpha438.7IL10, TNF, IL8, IL6, IL1B
5okt3438.6CD79A, TNF, FCER2, ICAM1, IL6, IL10
6lipoteichoic acid438.5IL1B, CD14, IL6, IL8, IL10, TNF
75 aminosalicylic acid438.5IL8, IL10, MPO, TNF, IL1B
8sulfasalazine28 43 49 1211.5TNF, MPO, ICAM1, IL8, IL1B, HP
9triptolide438.5IL1B, ICAM1, IL8, TNF, CD14, IL6
10peptidoglycan43 289.4TNF, IL1B, CD14, IL6, IL8, IL10
11rantes438.4CXCL2, IL10, ICAM1, CD14, IL8, IL1B
12diphenyleneiodonium438.3SOD2, SOD1, ICAM1, IL8, IL1B, MPO
13gm-csf43 289.3IL6, IL1B, CD14, IL8, IL10, TNF
14polymyxin b438.2TNF, ICAM1, IL10, IL8, IL6, IL1B
15budesonide43 49 1210.2IL1B, IL8, IGHE, SFTPD, TNF, MPO
16il-12438.1TNF, IL10, IL8, IL1B, IL6
17fmlp438.1ICAM1, IL8, CD14, IL1B, FCER2, MPO
18herbimycin a43 599.0IL8, IL1B, ICAM1, FCER2, TNF, IL6
19pdtc437.9TNF, FCER2, SOD2, SOD1, ICAM1, IL8
20ascorbic acid43 248.9CD79A, HP, IGHE, ICAM1, ALB, SOD1
21ulinastatin437.9MPO, SOD1, ICAM1, IL10, IL8, IL6
22calcitriol43 59 24 1210.9CD14, IL10, SOD2, FCER2, TNF, ALB
23ivig437.9ALB, CD79A, IGHE, TNF, IL10, IL6
24hydrocortisone43 2 59 1210.9TNF, IGHE, FCER2, IL10, IL8, IL6
258-isoprostane437.9TNF, MPO, SOD1, ICAM1, IL10, IL8
26vitamin d437.8CD79A, CD14, ALB, HP, IL6, IL10
27pentoxifylline43 128.7TNF, MPO, ICAM1, IL10, IL8, IL6
28tarc437.7CXCL2, ICAM1, IL10, IL8, IGHE, TNF
29groalpha437.7TNF, CXCL2, ICAM1, IL10, IL8, IL6
30ccl343 288.6TNF, IL1B, IL6, IL10, IL8, CXCL2
31neopterin437.6TNF, FCER2, ICAM1, IL10, IL8, IL6
32creatinine437.5ALB, SOD2, MPO, SOD1, IL6, HP
33hyaluronic acid43 248.5CD79A, IL6, HP, ALB, IL1B, IL8
34methotrexate49 43 129.5IL6, SOD2, IL10, IL1B, ALB, CD79A
35prednisolone43 28 129.5IGHE, SFTPD, TNF, MPO, IL10, IL6
36sb 20358043 598.3IL1B, FCER2, CXCL2, ICAM1, IL10, TNF
37indomethacin43 28 59 1210.2IL1B, CD79A, ALB, IL6, SOD1, SOD2
38cyclosporin a43 28 599.2CD79A, IL10, IGHE, TNF, CD14, HP
39cycloheximide437.2CD14, IL6, IL8, ICAM1, SOD2, TNF
40fibrinogen437.1TNF, CXCL2, IL6, ALB, CD14, CD79A
41ly294002437.1TNF, SOD2, CD14, IL6, IL8, CXCL2
42endotoxin437.0ICAM1, IL10, IL8, IL6, IL1B, HP
43h2o2436.9CXCL2, SOD1, SOD2, MPO, TNF, IL8
44pge2436.4MPO, FCER2, CXCL2, ICAM1, IL10, IL8
45histamine43 28 248.3IGHE, SFTPD, TNF, MPO, FCER2, ICAM1
46n acetylcysteine436.3IL6, IL1B, CD79A, IL8, ICAM1, IGHE
47nitric oxide43 24 128.0HP, IL1B, ICAM1, CXCL2, SOD1, SOD2
48vegf435.8CD14, HP, IL1B, IL6, CD79A, ICAM1
49dexamethasone43 49 28 128.7SFTPD, IGHE, CD79A, TNF, FCER2, SOD2
50lactate435.1IGHE, SFTPD, TNF, MPO, FCER2, SOD2

GO Terms for genes affiliated with Extrinsic Allergic Alveolitis

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Cellular components related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1membrane raftGO:00451219.4CD79A, CD14, TNF
2external side of plasma membraneGO:00098978.5TNF, FCER2, ICAM1, IL6, CD79A
3extracellular vesicular exosomeGO:00700627.9MPO, FCER2, SOD1, ICAM1, HP, ALB
4extracellular regionGO:00055765.8IGHE, SFTPD, TNF, SOD1, CXCL2, IL8
5extracellular spaceGO:00056155.4CD14, SFTPD, TNF, MPO, SOD1, CXCL2

Biological processes related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idNameGO IDScoreTop Affiliating Genes
1response to superoxideGO:000030310.2SOD2, SOD1
2hydrogen peroxide biosynthetic processGO:005066510.1SOD2, SOD1
3superoxide anion generationGO:004255410.0SOD2, SOD1
4positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292510.0TNF, FCER2
5defense response to bacteriumGO:004274210.0SFTPD, IL10, HP
6response to copper ionGO:004668810.0ICAM1, SOD1
7sequestering of triglycerideGO:003073010.0IL1B, TNF
8removal of superoxide radicalsGO:001943010.0SOD1, SOD2, MPO
9response to hydrogen peroxideGO:004254210.0HP, SOD1, SOD2
10positive regulation of calcidiol 1-monooxygenase activityGO:006055910.0IL1B, TNF
11positive regulation of heterotypic cell-cell adhesionGO:00341169.9TNF, IL1B
12positive regulation of fever generationGO:00316229.9TNF, IL1B
13response to electrical stimulusGO:00516029.9IL6, SOD2
14receptor biosynthetic processGO:00328009.9IL10, TNF
15negative regulation of cytokine secretion involved in immune responseGO:00027409.9TNF, IL10
16positive regulation of chemokine biosynthetic processGO:00450809.9TNF, IL1B
17superoxide metabolic processGO:00068019.9SOD1, SOD2
18regulation of I-kappaB kinase/NF-kappaB signalingGO:00431229.9IL1B, TNF
19regulation of mitochondrial membrane potentialGO:00518819.9SOD2, SOD1
20positive regulation of membrane protein ectodomain proteolysisGO:00510449.8IL1B, TNF
21negative regulation of lipid catabolic processGO:00509959.8TNF, IL1B
22response to ethanolGO:00454719.8CD14, ICAM1, SOD1
23response to heatGO:00094089.8SOD1, IL6, CD14
24epithelial cell proliferation involved in salivary gland morphogenesisGO:00606649.8TNF, IL6
25muscle cell cellular homeostasisGO:00467169.8SOD1, IL6
26negative regulation of lipid storageGO:00108889.8TNF, IL6
27positive regulation of cytokine secretionGO:00507159.7CD14, IL10, TNF
28response to lipopolysaccharideGO:00324969.7MPO, SOD2, IL6
29negative regulation of growth of symbiont in hostGO:00441309.7IL10, MPO, TNF
30embryonic digestive tract developmentGO:00485669.7TNF, IL8
31response to activityGO:00148239.7TNF, SOD2, IL10
32cellular response to lipopolysaccharideGO:00712229.6ICAM1, IL10, IL8, CD14
33positive regulation of chemokine productionGO:00327229.6IL6, TNF
34response to nutrient levelsGO:00316679.6SOD1, IL6
35negative regulation of fat cell differentiationGO:00455999.5TNF, SOD2, IL6
36response to mechanical stimulusGO:00096129.5TNF, MPO, IL6
37positive regulation of interleukin-6 productionGO:00327559.5IL1B, IL6, TNF
38activation of MAPK activityGO:00001879.5TNF, SOD1, IL1B
39response to glucocorticoidGO:00513849.4IL6, IL10, TNF
40response to molecule of bacterial originGO:00022379.4CXCL2, IL10, IL8
41positive regulation of cytokine productionGO:00018199.3TNF, SOD1
42positive regulation of NF-kappaB import into nucleusGO:00423469.3IL1B, TNF
43positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.2TNF, IL10, IL6, IL1B
44positive regulation of NF-kappaB transcription factor activityGO:00510929.2TNF, ICAM1, IL6, IL1B
45negative regulation of apoptotic processGO:00430668.9ALB, IL6, IL10, MPO
46negative regulation of cell proliferationGO:00082858.9IL1B, IL6, IL8, SOD2, TNF
47positive regulation of nitric oxide biosynthetic processGO:00454298.9IL1B, IL6, ICAM1, SOD2, TNF
48immune responseGO:00069558.8IL1B, IL8, CXCL2, IGHE
49response to drugGO:00424938.5TNF, SOD2, SOD1, ICAM1, IL10, IL6
50inflammatory responseGO:00069547.8TNF, CXCL2, IL10, IL8, IL6, IL1B

Molecular functions related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1antioxidant activityGO:00162099.7ALB, HP
2superoxide dismutase activityGO:00047849.7SOD2, SOD1
3cytokine activityGO:00051258.8IL1B, IL6, IL10, TNF
4protein bindingGO:00055155.9SFTPD, TNF, SOD1, CXCL2, ICAM1, IL8

Products for genes affiliated with Extrinsic Allergic Alveolitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Extrinsic Allergic Alveolitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet