MCID: EXT034
MIFTS: 54

Extrinsic Allergic Alveolitis malady

Rare diseases, Respiratory diseases, Immune diseases categories

Aliases & Classifications for Extrinsic Allergic Alveolitis

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Aliases & Descriptions for Extrinsic Allergic Alveolitis:

Name: Extrinsic Allergic Alveolitis 8 61
Alveolitis 8 44 61
Hypersensitivity Pneumonitis 8 42
Extrinsic Allergic Pneumonia Hypersensitivity Pneumonitis 42
 
Allergic Interstitial Pneumonitis 42
Alveolitis, Extrinsic Allergic 42
Pneumonitis Hypersensitivity 44
Allergic Pneumonitis 42


Classifications:



External Ids:

Disease Ontology8 DOID:841
ICD9CM27 495.9, 495
MeSH33 D000542
NCIt39 C34369
ICD1025 J67, J67.8, J67.9

Summaries for Extrinsic Allergic Alveolitis

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Disease Ontology:8 An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss.

MalaCards based summary: Extrinsic Allergic Alveolitis, also known as alveolitis, is related to allergic bronchopulmonary aspergillosis and pulmonary fibrosis, idiopathic. An important gene associated with Extrinsic Allergic Alveolitis is FCER2 (Fc fragment of IgE, low affinity II, receptor for (CD23)), and among its related pathways are superoxide radicals degradation and IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types. The compounds taurine chloramine and allergens have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and monocytes, and related mouse phenotypes are skeleton and digestive/alimentary.

Related Diseases for Extrinsic Allergic Alveolitis

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Diseases related to Extrinsic Allergic Alveolitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 220)
idRelated DiseaseScoreTop Affiliating Genes
1allergic bronchopulmonary aspergillosis31.1SFTPD, IGHE
2pulmonary fibrosis, idiopathic30.9IL1B, IL8, SFTPD
3aspergillosis30.9CD79A, SFTPD
4sinusitis30.8CD79A, IGHE
5pulmonary fibrosis30.8IL1B, IL8, SOD1, MPO, SFTPD
6pulmonary sarcoidosis30.7ICAM1, TNF, SFTPD
7interstitial lung disease30.7CD79A, IL1B, TNF, SFTPD
8bronchiolitis30.6IL8, FCER2, IGHE
9pulmonary eosinophilia30.5IL8, SFTPD, IGHE
10cork-handlers' disease30.4ALB, IL8, SOD2, MPO
11arthritis30.3IL1B, IL6, IL8, TNF
12hiv-130.3CD14, HP, FCER2, SFTPD
13eosinophilia29.9CD79A, CD14, IL8, IL10, FCER2, MPO
14asthma29.5CD79A, CD14, IL1B, IL8, IL10, ICAM1
15pneumonia29.4CD79A, IL1B, IL6, IL8, IL10, ICAM1
16tuberculosis29.3CD79A, ALB, HP, IL1B, IL10, TNF
17vasculitis29.2CD79A, CD14, ALB, ICAM1, MPO, TNF
18colitis29.1IL1B, IL6, IL8, IL10, CXCL2, MPO
19connective tissue disease28.8CD79A, ALB, IL6, IL10, ICAM1, MPO
20ulcerative colitis28.7CD79A, CD14, IL1B, IL6, IL8, IL10
21rheumatoid arthritis28.5CD79A, CD14, HP, IL1B, IL6, IL8
22atherosclerosis28.2CD14, ALB, HP, IL1B, IL6, IL8
23acute poststreptococcal glomerulonephritis10.6CD79A
24intervertebral disc disease10.6IL1B
25polyarteritis nodosa10.6MPO
26urethritis10.5CD79A
27strongyloidiasis10.5IGHE
28hemoglobinuria10.5HP
29mononeuropathy10.5MPO
30amebiasis10.5CD79A
31prostatitis10.5CD79A
32brucellosis10.5CD79A
33eosinophilic gastroenteritis10.5IGHE
34pyelonephritis10.5CD79A
35muckle-wells syndrome10.5IL1B
36filariasis10.5IGHE
37methemoglobinemia10.5HP
38bird fancier's lung10.5
39farmer's lung10.5
40familial hypersensitivity pneumonitis10.5
41rheumatoid vasculitis10.4ICAM1
42chronic conjunctivitis10.4FCER2, IGHE
43hypersensitivity vasculitis10.4CD79A, MPO
44intrinsic asthma10.4FCER2, IGHE
45conjunctivitis10.4CD79A, IGHE
46immunoglobulin g deficiency10.4CD79A, IGHE
47acute monocytic leukemia10.4CD14, MPO
48selective iga deficiency disease10.4CD79A, IL10
49immunodeficiency, x-linked, with hyper-igm10.4CD79A, IGHE
50cutaneous leishmaniasis10.4IL10, FCER2

Graphical network of the top 20 diseases related to Extrinsic Allergic Alveolitis:



Diseases related to extrinsic allergic alveolitis

Symptoms for Extrinsic Allergic Alveolitis

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Drugs & Therapeutics for Extrinsic Allergic Alveolitis

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Drug clinical trials:

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Search NIH Clinical Center for Extrinsic Allergic Alveolitis

Genetic Tests for Extrinsic Allergic Alveolitis

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Anatomical Context for Extrinsic Allergic Alveolitis

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MalaCards organs/tissues related to Extrinsic Allergic Alveolitis:

31
Lung, Testes, Monocytes, Skin, Myeloid, Nk cells, T cells, Neutrophil

Animal Models for Extrinsic Allergic Alveolitis or affiliated genes

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MGI Mouse Phenotypes related to Extrinsic Allergic Alveolitis:

35 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.1CD14, IL6, IL10, SOD1, TNF, IL1B
2MP:00053818.0IL10, IL6, ALB, TNF, FCER2, ICAM1
3MP:00053918.0ICAM1, IL10, IL6, SOD1, SOD2, TNF
4MP:00053707.7ALB, HP, IL6, IL10, SOD1, SOD2
5MP:00020067.6SOD2, TNF, ALB, ICAM1, IL10, IL6
6MP:00053797.5IL10, SOD1, ICAM1, ALB, IL6, TNF
7MP:00053697.4TNF, MPO, SOD2, SOD1, ICAM1, IL10
8MP:00036317.4SOD2, TNF, SOD1, ICAM1, IL1B, CD79A
9MP:00053857.3IL1B, HP, IL6, IL10, TNF, MPO
10MP:00053847.0ICAM1, TNF, FCER2, SOD2, SOD1, ALB
11MP:00107686.3ICAM1, IL10, IL6, HP, ALB, CD14
12MP:00053975.7IGHE, IL10, ICAM1, SOD1, SOD2, FCER2
13MP:00053875.7FCER2, MPO, TNF, SFTPD, IL1B, SOD2
14MP:00053765.5ALB, SFTPD, TNF, MPO, FCER2, SOD2

Publications for Extrinsic Allergic Alveolitis

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Articles related to Extrinsic Allergic Alveolitis:

(show top 50)    (show all 160)
idTitleAuthorsYear
1
New occupational and environmental causes of asthma and extrinsic allergic alveolitis. (23153603)
2012
2
Acute life-threatening extrinsic allergic alveolitis in a paint controller. (21824996)
2011
3
Significance of specific IgG against sensitizing antigens in extrinsic allergic alveolitis: serological methods in EAA. (21924863)
2011
4
Extrinsic allergic alveolitis: incidence and mortality in the general population. (17307752)
2007
5
Extrinsic allergic alveolitis with eosinophil infiltration induced by 1,1,1,2-tetrafluoroethane (HFC-134a): a case report. (17827848)
2007
6
An unusual case of an acquired acral partial lipodystrophy (Barraquer-Simons syndrome) in a patient with extrinsic allergic alveolitis. (16716174)
2006
7
Production of soluble tumor necrosis factor receptors and tumor necrosis factor-alpha by alveolar macrophages in sarcoidosis and extrinsic allergic alveolitis. (15653992)
2005
8
Blood myeloid and lymphoid dendritic cells reflect Th1/Th2 balance in sarcoidosis and extrinsic allergic alveolitis. (15314973)
2003
9
Extrinsic allergic alveolitis induced by the yeast Debaryomyces hansenii. (12449192)
2002
10
Biochemical characteristics of fluid and cells of bronchoalveolar washings in patients with extrinsic allergic alveolitis]. (12474462)
2002
11
IgG antibodies typical for extrinsic allergic alveolitis--an inter-laboratory quality assessment. (11726311)
2001
12
Respiratory syndrome very similar to extrinsic allergic alveolitis due to Penicillium verrucosum in workers in a cheese factory. (11307594)
2001
13
Pet-fish food lung- a new form of extrinsic allergic alveolitis. (10756166)
2000
14
Effects of erythromycin on experimental extrinsic allergic alveolitis. (10051731)
1999
15
Elevated levels of soluble TNF receptors in bronchoalveolar lavage fluid in extrinsic allergic alveolitis. (10469029)
1999
16
Aerobiological analysis in a salami factory: a possible case of extrinsic allergic alveolitis by Penicillium camembertii. (10421864)
1999
17
Paper mill workers and chronic extrinsic allergic alveolitis. (8623683)
1996
18
Extrinsic allergic alveolitis and asthma in a sawmill worker: case report and review of the literature. (8130843)
1994
19
Expression of the adhesion molecule ICAM-1 on alveolar macrophages and in serum in extrinsic allergic alveolitis. (7903468)
1993
20
Extrinsic allergic alveolitis due to exposure to esparto dust. (1506815)
1992
21
Extrinsic allergic alveolitis: problems in diagnosis and a potential use for computed tomography. (1615180)
1992
22
Extrinsic allergic alveolitis secondary to carmine. (1678130)
1991
23
High-resolution computed tomography in extrinsic allergic alveolitis. (1999081)
1991
24
Mimics of sarcoidosis. Extrinsic allergic alveolitis. (1670003)
1991
25
Clinical guidelines and indications for bronchoalveolar lavage (BAL): extrinsic allergic alveolitis. (2292296)
1990
26
Limitations of hospital discharge diagnoses for surveillance of extrinsic allergic alveolitis. (2343875)
1990
27
Reversible pulmonary arterial hypertension in a 6-year-old girl with extrinsic allergic alveolitis. (2919518)
1989
28
Current concepts on bronchoalveolar lavage cells in extrinsic allergic alveolitis. (3068746)
1988
29
Extrinsic allergic alveolitis caused by a cold water humidifier. (3660296)
1987
30
Mast cells, atypical lymphocytes, and neutrophils in bronchoalveolar lavage in extrinsic allergic alveolitis. Comparison with other interstitial lung diseases. (2432812)
1987
31
Farmers' lung and extrinsic allergic alveolitis. (3684935)
1987
32
Antibody measurement in extrinsic allergic alveolitis. (6723835)
1984
33
Sporobolomyces: a possible cause of extrinsic allergic alveolitis. (6684133)
1983
34
Pulmonary arterial hypertension in extrinsic allergic alveolitis (EAA) (7091903)
1982
35
Bronchoalveolar lavage and transbronchial lung biopsy in sarcoidosis and extrinsic allergic alveolitis. (7173351)
1982
36
Extrinsic allergic alveolitis due to milk allergy: case report and review of the literature. (7065466)
1982
37
Phospholipids and microviscosity study in broncho-alveolar lavage fluids from control subjects and from patients with extrinsic allergic alveolitis. (7285366)
1981
38
Sawmill work and extrinsic allergic alveolitis. (6937828)
1980
39
Trapped air in extrinsic allergic alveolitis. (7444185)
1980
40
Clinical and immunological studies in pulmonary extrinsic allergic alveolitis. (Watson Prize Lecture, Royal College of Physicians and Surgeons, Glasgow, 4 April 1977). (152974)
1978
41
Extrinsic allergic alveolitis from bird exposure. Studies on the immediate hypersensitivity reaction. (563307)
1977
42
Editorial: Extrinsic allergic alveolitis. (1260333)
1976
43
Immunologically mediated lung diseases. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis. (944440)
1976
44
Extrinsic allergic alveolitis in Scottish maltworkers. (1252813)
1976
45
Extrinsic allergic alveolitis. (1089312)
1975
46
Extrinsic allergic alveolitis due to rat serum proteins. (1053443)
1975
47
Extrinsic allergic alveolitis owing to hypersensitivity to chickens-significance of sputum precipitins. (4209494)
1974
48
Extrinsic allergic alveolitis. (4574409)
1973
49
A bovine disease similar to farmer's lung: extrinsic allergic alveolitis. (4252199)
1971
50
Irreversible lung damage in extrinsic allergic alveolitis from pigeon dust inhalation. (5463319)
1970

Variations for Extrinsic Allergic Alveolitis

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Expression for genes affiliated with Extrinsic Allergic Alveolitis

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Search GEO for disease gene expression data for Extrinsic Allergic Alveolitis.

Pathways for genes affiliated with Extrinsic Allergic Alveolitis

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Pathways related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 57)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8SOD2, SOD1
29.7IL6, IL1B
3
Show member pathways
RANKL/RANK Signaling Pathway36
Apoptosis and survival APRIL and BAFF signaling59
9.6ICAM1, FCER2, IL10
49.4IL10, FCER2, IGHE
59.4IL1B, IL8, IL6
69.3SOD1, IL1B, IL6
79.3IL8, IL6, ICAM1
89.2CD14, MPO, IL8, IL6
99.1IL6, IL1B, TNF
10
Show member pathways
9.1ICAM1, IL6, IL8, CD14
11
Show member pathways
9.0SOD2, SOD1, IL8, IL6
128.9TNF, ICAM1, IL1B, MPO
13
Show member pathways
8.9FCER2, CD79A, TNF, CD14, IL1B
14
Show member pathways
8.8IL6, TNF, IL1B, IL10
15
Show member pathways
IL27-mediated signaling events36
8.8IL1B, TNF, IL10, IL6
168.7ICAM1, IL8, IL6, TNF
178.7IL6, FCER2, TNF, IL1B, CD14
188.5CD14, IL1B, IL6, IL10, TNF
198.5IL1B, TNF, IL10, CD14, IL6
20
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
8.5TNF, IL1B, IL6, CD79A, IL10
21
Show member pathways
Immune response MIF in innate immunity response59
8.5IL6, IL8, CD14, TNF, IL1B
22
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways59
Immune response IL 1 signaling pathway59
8.5IL1B, CD14, IL8, TNF, IL6
238.5ICAM1, TNF, MPO, HP, IL6
248.4IL1B, IL6, IL8, TNF, IL10
258.4IL10, IL6, IL8, IL1B, TNF
26
Show member pathways
8.4IL10, IL8, TNF, IL1B, IL6
278.4IL1B, IL6, IL10, ICAM1, TNF
28
Show member pathways
8.4IL1B, IL6, IL10, ICAM1, TNF
29
Show member pathways
8.4IL8, TNF, ICAM1, IL1B, IL6
308.4ICAM1, IL8, IL6, IL1B, TNF
31
Show member pathways
8.3CD14, IL8, CXCL2, IL1B, IL6
32
Show member pathways
Transcription NF kB signaling pathway59
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response59
8.3CD14, IL6, TNF, SFTPD, IL1B, IL8
33
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway59
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB59
Development Angiopoietin Tie2 signaling59
8.3IL1B, MPO, IL6, IL10, TNF, CD14
348.2IL6, IL10, IL1B, CD14, TNF, IL8
35
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
8.2TNF, IL10, IL8, CD14, IL1B, IL6
368.2IL10, TNF, CD14, IL1B, IL6, IL8
37
Show member pathways
8.1SOD2, SOD1, IL8, IL6, IL1B, TNF
388.1IL1B, IL6, IL8, IL10, ICAM1, TNF
398.0IL6, IL10, CXCL2, TNF, IL1B
40
Show member pathways
7.9IL1B, IL6, CXCL2, IL8, TNF
417.9TNF, CXCL2, ICAM1, IL6, IL1B
427.8IL1B, IL8, ICAM1, CXCL2, TNF, CD14
437.7IL1B, CD14, IL6, IL8, TNF, CXCL2
44
Show member pathways
7.6IL6, IL1B, IL8, IL10, CXCL2, TNF
45
Show member pathways
7.6TNF, CXCL2, IL10, IL8, IL6, IL1B
46
Show member pathways
7.6TNF, IL8, CXCL2, IL1B, IL6, IL10
477.6IL1B, IL6, ICAM1, CXCL2, TNF, IL8
48
Show member pathways
thioredoxin pathway36
7.2MPO, SOD2, ICAM1, IL6, IL1B, SOD1
49
Show member pathways
6.9IL1B, IL6, IL8, IL10, CXCL2, SOD2

Compounds for genes affiliated with Extrinsic Allergic Alveolitis

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Compounds related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 303)
idCompoundScoreTop Affiliating Genes
1taurine chloramine448.8TNF, MPO, IL8, IL6, IL1B
2allergens448.8FCER2, SFTPD, IGHE, IL10, CD79A, CD14
3methacholine44 50 1110.7CD14, IL8, ICAM1, CD79A, MPO, IGHE
4mip 1alpha448.7IL10, TNF, IL8, IL6, IL1B
5okt3448.6CD79A, TNF, FCER2, ICAM1, IL6, IL10
6lipoteichoic acid448.5IL1B, CD14, IL6, IL8, IL10, TNF
75 aminosalicylic acid448.5IL8, IL10, MPO, TNF, IL1B
8sulfasalazine28 44 50 1111.5TNF, MPO, ICAM1, IL8, IL1B, HP
9triptolide448.5IL1B, ICAM1, IL8, TNF, CD14, IL6
10peptidoglycan44 289.4TNF, IL1B, CD14, IL6, IL8, IL10
11rantes448.4CXCL2, IL10, ICAM1, CD14, IL8, IL1B
12diphenyleneiodonium448.3SOD2, SOD1, ICAM1, IL8, IL1B, MPO
13gm-csf44 289.3IL6, IL1B, CD14, IL8, IL10, TNF
14polymyxin b448.2TNF, ICAM1, IL10, IL8, IL6, IL1B
15budesonide44 50 1110.2IL1B, IL8, IGHE, SFTPD, TNF, MPO
16il-12448.1TNF, IL10, IL8, IL1B, IL6
17fmlp448.1ICAM1, IL8, CD14, IL1B, FCER2, MPO
18herbimycin a44 609.0IL8, IL1B, ICAM1, FCER2, TNF, IL6
19pdtc447.9TNF, FCER2, SOD2, SOD1, ICAM1, IL8
20ascorbic acid44 248.9CD79A, HP, IGHE, ICAM1, ALB, SOD1
21ulinastatin447.9MPO, SOD1, ICAM1, IL10, IL8, IL6
22calcitriol44 60 24 1110.9CD14, IL10, SOD2, FCER2, TNF, ALB
23ivig447.9ALB, CD79A, IGHE, TNF, IL10, IL6
24hydrocortisone44 1 60 1110.9TNF, IGHE, FCER2, IL10, IL8, IL6
258-isoprostane447.9TNF, MPO, SOD1, ICAM1, IL10, IL8
26vitamin d447.8CD79A, CD14, ALB, HP, IL6, IL10
27pentoxifylline44 118.7TNF, MPO, ICAM1, IL10, IL8, IL6
28tarc447.7CXCL2, ICAM1, IL10, IL8, IGHE, TNF
29groalpha447.7TNF, CXCL2, ICAM1, IL10, IL8, IL6
30ccl344 288.6TNF, IL1B, IL6, IL10, IL8, CXCL2
31neopterin447.6TNF, FCER2, ICAM1, IL10, IL8, IL6
32creatinine447.5ALB, SOD2, MPO, SOD1, IL6, HP
33hyaluronic acid44 248.5CD79A, IL6, HP, ALB, IL1B, IL8
34methotrexate50 44 119.5IL6, SOD2, IL10, IL1B, ALB, CD79A
35prednisolone44 28 119.5IGHE, SFTPD, TNF, MPO, IL10, IL6
36sb 20358044 608.3IL1B, FCER2, CXCL2, ICAM1, IL10, TNF
37indomethacin44 28 60 1110.2IL1B, CD79A, ALB, IL6, SOD1, SOD2
38cyclosporin a44 28 609.2CD79A, IL10, IGHE, TNF, CD14, HP
39cycloheximide447.2CD14, IL6, IL8, ICAM1, SOD2, TNF
40fibrinogen447.1TNF, CXCL2, IL6, ALB, CD14, CD79A
41ly294002447.1TNF, SOD2, CD14, IL6, IL8, CXCL2
42endotoxin447.0ICAM1, IL10, IL8, IL6, IL1B, HP
43h2o2446.9CXCL2, SOD1, SOD2, MPO, TNF, IL8
44pge2446.4MPO, FCER2, CXCL2, ICAM1, IL10, IL8
45histamine44 28 248.3IGHE, SFTPD, TNF, MPO, FCER2, ICAM1
46n acetylcysteine446.3IL6, IL1B, CD79A, IL8, ICAM1, IGHE
47nitric oxide44 24 118.0HP, IL1B, ICAM1, CXCL2, SOD1, SOD2
48vegf445.8CD14, HP, IL1B, IL6, CD79A, ICAM1
49dexamethasone44 50 28 118.7SFTPD, IGHE, CD79A, TNF, FCER2, SOD2
50lactate445.1IGHE, SFTPD, TNF, MPO, FCER2, SOD2

GO Terms for genes affiliated with Extrinsic Allergic Alveolitis

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Cellular components related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1membrane raftGO:00451219.4CD79A, CD14, TNF
2external side of plasma membraneGO:00098978.5TNF, FCER2, ICAM1, IL6, CD79A
3extracellular vesicular exosomeGO:00700627.9MPO, FCER2, SOD1, ICAM1, HP, ALB
4extracellular regionGO:00055765.8IGHE, SFTPD, TNF, SOD1, CXCL2, IL8
5extracellular spaceGO:00056155.4CD14, SFTPD, TNF, MPO, SOD1, CXCL2

Biological processes related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idNameGO IDScoreTop Affiliating Genes
1response to superoxideGO:000030310.2SOD2, SOD1
2hydrogen peroxide biosynthetic processGO:005066510.1SOD2, SOD1
3superoxide anion generationGO:004255410.1SOD1, SOD2
4positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292510.0TNF, FCER2
5defense response to bacteriumGO:004274210.0HP, IL10, SFTPD
6response to copper ionGO:004668810.0SOD1, ICAM1
7sequestering of triglycerideGO:003073010.0IL1B, TNF
8response to hydrogen peroxideGO:004254210.0SOD1, SOD2, HP
9response to electrical stimulusGO:005160210.0SOD2, IL6
10removal of superoxide radicalsGO:001943010.0MPO, SOD2, SOD1
11positive regulation of calcidiol 1-monooxygenase activityGO:006055910.0IL1B, TNF
12positive regulation of fever generationGO:00316229.9TNF, IL1B
13receptor biosynthetic processGO:00328009.9TNF, IL10
14positive regulation of heterotypic cell-cell adhesionGO:00341169.9TNF, IL1B
15negative regulation of cytokine secretion involved in immune responseGO:00027409.9IL10, TNF
16positive regulation of chemokine biosynthetic processGO:00450809.9IL1B, TNF
17superoxide metabolic processGO:00068019.9SOD2, SOD1
18regulation of I-kappaB kinase/NF-kappaB signalingGO:00431229.9TNF, IL1B
19positive regulation of membrane protein ectodomain proteolysisGO:00510449.8IL1B, TNF
20negative regulation of lipid catabolic processGO:00509959.8TNF, IL1B
21response to ethanolGO:00454719.8SOD1, ICAM1, CD14
22response to heatGO:00094089.8CD14, IL6, SOD1
23muscle cell cellular homeostasisGO:00467169.8IL6, SOD1
24regulation of mitochondrial membrane potentialGO:00518819.8SOD2, SOD1
25epithelial cell proliferation involved in salivary gland morphogenesisGO:00606649.8TNF, IL6
26negative regulation of lipid storageGO:00108889.8TNF, IL6
27positive regulation of cytokine secretionGO:00507159.7TNF, IL10, CD14
28response to lipopolysaccharideGO:00324969.7SOD2, MPO, IL6
29negative regulation of growth of symbiont in hostGO:00441309.7IL10, MPO, TNF
30response to nutrient levelsGO:00316679.7IL6, SOD1
31response to activityGO:00148239.7TNF, SOD2, IL10
32embryonic digestive tract developmentGO:00485669.7IL8, TNF
33cellular response to lipopolysaccharideGO:00712229.6ICAM1, IL10, IL8, CD14
34positive regulation of chemokine productionGO:00327229.6TNF, IL6
35negative regulation of fat cell differentiationGO:00455999.5IL6, SOD2, TNF
36response to mechanical stimulusGO:00096129.5MPO, IL6, TNF
37positive regulation of interleukin-6 productionGO:00327559.5TNF, IL6, IL1B
38activation of MAPK activityGO:00001879.5SOD1, TNF, IL1B
39response to glucocorticoidGO:00513849.4IL10, TNF, IL6
40response to molecule of bacterial originGO:00022379.4IL8, IL10, CXCL2
41positive regulation of cytokine productionGO:00018199.3TNF, SOD1
42positive regulation of NF-kappaB import into nucleusGO:00423469.3TNF, IL1B
43positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.2TNF, IL10, IL6, IL1B
44positive regulation of NF-kappaB transcription factor activityGO:00510929.2IL6, ICAM1, IL1B, TNF
45negative regulation of apoptotic processGO:00430668.9MPO, IL10, IL6, ALB
46negative regulation of cell proliferationGO:00082858.9IL8, TNF, SOD2, IL6, IL1B
47positive regulation of nitric oxide biosynthetic processGO:00454298.9TNF, IL1B, IL6, ICAM1, SOD2
48immune responseGO:00069558.8CXCL2, IGHE, IL1B, IL8
49response to drugGO:00424938.5SOD2, IL6, SOD1, ICAM1, IL10, TNF
50inflammatory responseGO:00069547.8IL1B, CD14, IL6, IL8, IL10, TNF

Molecular functions related to Extrinsic Allergic Alveolitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1antioxidant activityGO:00162099.7ALB, HP
2superoxide dismutase activityGO:00047849.7SOD2, SOD1
3cytokine activityGO:00051258.8IL1B, IL6, IL10, TNF
4protein bindingGO:00055155.9SFTPD, TNF, SOD1, CXCL2, ICAM1, IL8

Sources for Extrinsic Allergic Alveolitis

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet