HP
MCID: EXT034
MIFTS: 55

Extrinsic Allergic Alveolitis (HP) malady

Respiratory, Immune categories

Summaries for Extrinsic Allergic Alveolitis

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss.

MalaCards: Extrinsic Allergic Alveolitis, also known as hypersensitivity pneumonitis, is related to allergic asthma and asthma. An important gene associated with Extrinsic Allergic Alveolitis is SFTPD (surfactant protein D), and among its related pathways are B cell receptor signaling pathway and Senescence and Autophagy. The compounds cycloheximide and pentoxifylline have been mentioned in the context of this disorder. Related mouse phenotypes are vision/eye and nervous system.

Wikipedia:64 Hypersensitivity pneumonitis (HP; also called extrinsic allergic alveolitis, EAA) is an inflammation of... more...

Aliases & Classifications for Extrinsic Allergic Alveolitis

Sources:
8Disease Ontology, 49Orphanet, 61UMLS, 43NIH Rare Diseases, 45Novoseek, 57SNOMED-CT, 27ICD9CM, 40NCIt, 35MeSH, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet, 36MESH via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory, Immune


Characteristics (Orphanet epidemiological data):

49
extrinsic allergic alveolitis:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

extrinsic allergic alveolitis 8 49 61
hypersensitivity pneumonitis 8 43 49
alveolitis 8 45 61
extrinsic allergic pneumonia hypersensitivity pneumonitis 43
allergic interstitial pneumonitis 43
alveolitis, extrinsic allergic 43
pneumonitis hypersensitivity 45
allergic pneumonitis 43
hp 49


External Ids:

Disease Ontology8 DOID:841
ICD9CM27 495.9, 495
NCIt40 C34369
MeSH35 D000542
ICD10 via Orphanet26 J67
SNOMED-CT via Orphanet58 37471005
UMLS via Orphanet62 C0002390
MESH via Orphanet36 D000542
ICD1025 J67, J67.8, J67.9

Related Diseases for Extrinsic Allergic Alveolitis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Extrinsic Allergic Alveolitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 463)
idRelated DiseaseScoreTop Affiliating Genes
1allergic asthma30.8FCER2, IL8, IL10, CD14, IGHE, ICAM1
2asthma30.7TGFB1, FCER2, IL1B, IL8, IL10, CD79A
3idiopathic pulmonary fibrosis30.7TGFB1, IL1B, IL8, SFTPD
4celiac disease30.4CD79A
5aspergillosis30.4CD79A, SFTPD
6allergic bronchopulmonary aspergillosis30.4IGHE, SFTPD
7cork-handlers' disease30.4ALB, IL8, MPO, SOD2
8pulmonary sarcoidosis30.4TNF, ICAM1, SFTPD
9psoriatic arthritis30.4IL1B, HLA-DRB1, TNF
10arthritis30.4IL6, IL1B, IL8, TNF
11atherosclerosis30.4TGFB1, ALB, IL6, IL1B, IL8, IL10
12crohn's disease30.3ALB, TNF
13pulmonary tuberculosis30.3IL10, HP, CD14, HLA-DRB1
14plasmodium falciparum malaria30.3IL10, HP, HLA-DRB1, ICAM1
15type 1 diabetes30.3ALB, IL1B, CD79A, HLA-DRB1
16sickle cell disease30.1HP
17hemochromatosis30.1HP
18acute poststreptococcal glomerulonephritis30.1CD79A
19hellp syndrome30.1HP
20hemoglobinuria30.1HP
21autoimmune hemolytic anemia30.1HP, CD79A
22polymyalgia rheumatica30.1HLA-DRB1
23coronary artery disease,30.1IL6, HP, CD14, ICAM1
24diabetic nephropathy30.1TGFB1, ALB, HP, SOD2
25bronchiolitis obliterans30.1IL8
26sinusitis30.1CD79A, IGHE
27bronchiolitis30.1FCER2, IL8, IGHE
28juvenile rheumatoid arthritis30.1IL6, HLA-DRB1, TNF
29colorectal cancer30.0TGFB1, CD14
30thrombocytopenia30.0ALB, IL6, HP, CD79A
31cystic fibrosis30.0ALB, IL8, HP, MPO, SFTPD
32hepatitis c30.0TGFB1, IL10, HP, HLA-DRB1, TNF
33vascular disease30.0IL6, IL1B, IL8, IL10, HP, TNF
34tuberculosis30.0ALB, IL1B, IL10, HP, CD79A, HLA-DRB1
35kawasaki disease29.9FCER2
36acute myocardial infarction29.9CD14
37gout29.9IL1B
38wilson disease29.9SOD1
39splenomegaly29.9HP
40kaposi's sarcoma29.9IL6
41coronary heart disease29.9IL6
42biliary atresia29.9TGFB1
43hepatopulmonary syndrome29.9ALB
44down syndrome29.9SOD1, SOD2
45viral hepatitis29.9CD14, HLA-DRB1
46thyroiditis29.9CD79A, HLA-DRB1
47bullous pemphigoid29.9FCER2, CD79A, IGHE
48adenocarcinoma29.9TGFB1, SOD2, SFTPD
49nephritis29.9ALB, CD79A, MPO
50thrombocytosis29.9IL6, IL1B, HP

Graphical network of the top 20 diseases related to Extrinsic Allergic Alveolitis:



Diseases related to extrinsic allergic alveolitis

Clinical Features for Extrinsic Allergic Alveolitis

Drugs & Therapeutics for Extrinsic Allergic Alveolitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Extrinsic Allergic Alveolitis

Genetic Tests for Extrinsic Allergic Alveolitis

Anatomical Context for Extrinsic Allergic Alveolitis

Animal Models for Extrinsic Allergic Alveolitis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

Publications for Extrinsic Allergic Alveolitis

Sources:
51PubMed
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Articles related to Extrinsic Allergic Alveolitis:

(show top 50)    (show all 158)
idTitleAuthorsYear
1
Influence of age on manifestation, VC and TLCO values and bronchoalveolar lavage cell counts of sarcoidosis and extrinsic allergic alveolitis: Fibrotic response as a hallmark of aging? (24406019)
2014
2
Acute life-threatening extrinsic allergic alveolitis in a paint controller. (21824996)
2011
3
Extrinsic allergic alveolitis: incidence and mortality in the general population. (17307752)
2007
4
Extrinsic allergic alveolitis (hypersensitivity pneumonitis) caused by Sphingobacterium spiritivorum from the water reservoir of a steam iron. (16145174)
2005
5
Cockade-like structures in alveolar macrophages in extrinsic allergic alveolitis - another piece in the puzzle? (15753631)
2005
6
Preliminary study on effect of pentoxifylline in treatment of extrinsic allergic alveolitis]. (15061967)
2004
7
Extrinsic allergic alveolitis in practice. (15114816)
2004
8
The HRCT features of extrinsic allergic alveolitis. (16088561)
2003
9
Extrinsic allergic alveolitis induced by the yeast Debaryomyces hansenii. (12449192)
2002
10
Biochemical characteristics of fluid and cells of bronchoalveolar washings in patients with extrinsic allergic alveolitis]. (12474462)
2002
11
IgG antibodies typical for extrinsic allergic alveolitis--an inter-laboratory quality assessment. (11726311)
2001
12
Extrinsic allergic alveolitis from a proteolytic enzyme. (11345286)
2001
13
Histologically proven extrinsic allergic alveolitis with severe obstructive pulmonary emphysema (10756171)
2000
14
A family with extrinsic allergic alveolitis caused by wild city pigeons: A case report. (10799626)
2000
15
Aerobiological analysis in a salami factory: a possible case of extrinsic allergic alveolitis by Penicillium camembertii. (10421864)
1999
16
Manganese superoxide dismutase, but not CuZn superoxide dismutase, is highly expressed in the granulomas of pulmonary sarcoidosis and extrinsic allergic alveolitis. (9700139)
1998
17
BN 52021 (a platelet activating factor-receptor antagonist) decreases alveolar macrophage-mediated lung injury in experimental extrinsic allergic alveolitis. (9705608)
1998
18
Paper mill workers and chronic extrinsic allergic alveolitis. (8623683)
1996
19
Experimental extrinsic allergic alveolitis and pulmonary angiitis induced by intratracheal or intravenous challenge with Corynebacterium parvum in sensitized rats. (8863677)
1996
20
Extrinsic allergic alveolitis and eosinophilic lung disease. (8832043)
1996
21
Air-trapping in extrinsic allergic alveolitis on computed tomography. (8893635)
1996
22
Extrinsic allergic alveolitis due to exposure to esparto dust. (1506815)
1992
23
Enhancement of the antigen-presenting function of monocytes by cholesterol: possible relevance to inflammatory mechanisms in extrinsic allergic alveolitis and atherosclerosis. (1370928)
1992
24
Extrinsic allergic alveolitis secondary to carmine. (1678130)
1991
25
Cellular modifications in the BAL-fluid in exposed farmers to antigens of extrinsic allergic alveolitis. (1669999)
1991
26
Limitations of hospital discharge diagnoses for surveillance of extrinsic allergic alveolitis. (2343875)
1990
27
Effect of smoking on the lipid composition of lung lining fluid and relationship between immunostimulatory lipids, inflammatory cells and foamy macrophages in extrinsic allergic alveolitis. (2090475)
1990
28
Transfer of 99mTc DTPA and bronchoalveolar lavage findings in patients with asymptomatic extrinsic allergic alveolitis. (2168589)
1990
29
Effect of lung T lymphocytes on fibroblasts in idiopathic pulmonary fibrosis and extrinsic allergic alveolitis. (2392789)
1990
30
Extrinsic allergic alveolitis caused by esparto (Stipa tenacissima). (2088103)
1990
31
Pathogenesis of extrinsic allergic alveolitis and pulmonary fibrosis induced by streptomyces thermohygroscopicus. (2517075)
1989
32
Histologic diagnosis of extrinsic allergic alveolitis. (3389449)
1988
33
Extrinsic allergic alveolitis caused by a cold water humidifier. (3660296)
1987
34
Farmers' lung and extrinsic allergic alveolitis. (3684935)
1987
35
Peripheral blood NK cells in patients with extrinsic allergic alveolitis: phenotype and function. (2437628)
1986
36
Bronchoalveolar lavage and transbronchial lung biopsy in sarcoidosis and extrinsic allergic alveolitis. (7173351)
1982
37
Extrinsic allergic alveolitis (hypersensitivity pneumonitis): immunopathology. (6984394)
1982
38
The inspiratory "squawk" in extrinsic allergic alveolitis and other pulmonary fibroses. (7170682)
1982
39
Extrinsic allergic alveolitis--management of established cases. (6962073)
1982
40
Hypersensitivity penumonitis (extrinsic allergic alveolitis). (7028022)
1981
41
Site and type of impaired lung function in extrinsic allergic alveolitis. (7394349)
1980
42
Extrinsic allergic alveolitis in a sawmill worker. A case report. (7001618)
1980
43
Immunopathological mechanisms involved in extrinsic allergic alveolitis. (6161532)
1980
44
Antigens implicated in the pathogenesis of extrinsic allergic alveolitis. (416062)
1978
45
Immunologically mediated lung diseases. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis. (944440)
1976
46
Extrinsic allergic alveolitis in Scottish maltworkers. (1252813)
1976
47
Letter: Extrinsic allergic alveolitis. (953591)
1976
48
Extrinsic allergic alveolitis. (4851992)
1974
49
Extrinsic allergic alveolitis. (4558051)
1972
50
Coffee worker's lung. A new example of extrinsic allergic alveolitis. (4922066)
1970

Genetic Variations for Extrinsic Allergic Alveolitis

Expression for genes affiliated with Extrinsic Allergic Alveolitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Extrinsic Allergic Alveolitis

Search GEO for disease gene expression data for Extrinsic Allergic Alveolitis.

Pathways for genes affiliated with Extrinsic Allergic Alveolitis

Sources:
30KEGG, 38NCBI BioSystems Database, 53R&D Systems, 52QIAGEN, 54Reactome, 12EMD Millipore
See all sources

Pathways related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show top 50)    (show all 54)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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10.2CD79A
210.2IL8
310.2IL1B
410.1SOD1
5
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10.1IL6
6
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10.0HLA-DRB1
79.9SOD1, SOD2
8
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9.7CXCL2
9
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9.6SOD2, SOD1, IL8
109.6IL6, IL8, CD14
119.5IL8, IL6, IL1B
129.5IGHE, FCER2, IL10
139.4ICAM1, HLA-DRB1, IL10
149.4IL1B, IL8, IL10, CD14
159.4CD14, IL8, MPO, IL6
169.4SFTPD, CD14, MPO, HLA-DRB1
179.2IL10, ICAM1, HLA-DRB1, FCER2
18
Hide members
9.2CD14, CXCL2, SOD2
199.2HLA-DRB1, CXCL2
209.1ICAM1, IL1B, MPO, TNF
21
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9.0CXCL2, TGFB1
229.0TNF, ICAM1, IL6, IL8
238.9CXCL2, IL1B, IL8, CD14
24
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8.8TNF, CD14, IL8, IL1B, IL6
25
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8.8IL8, IL1B, IL6, CD14, TNF
268.8IL6, ICAM1, TNF, MPO, HP
278.8IL1B, IL10, CD14, TNF, IL6
288.7IL1B, IL6, TNF, IL10, IL8
298.7IL6, IL10, IL8, IL1B, TNF
30
Cytokine production by Th17 cells in CF (Mouse model)
8.7IL8, TGFB1, IL6, CD14, ICAM1
318.7TNF, IL1B, IL6, ICAM1, IL10
32
Hide members
8.7IGHE, FCER2, CD79A, ICAM1, TNF
33
Immune response Bacterial infections in normal airways
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8.6SFTPD, TNF, IL8, IL1B, IL6, CD14
34
Development PDGF signaling via STATs and NF-kB
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8.5TNF, MPO, CD14, IL10, IL1B, IL6
35
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8.5TNF, HLA-DRB1, CD14, CD79A, FCER2, IL1B
36
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8.5IL6, IL1B, IL8, TNF, CD14, IL10
378.5CD14, IL1B, IL8, IL10, IL6, TNF
388.5CXCL2, IL8, IL6, IL1B, CD14
398.4FCER2, TNF, IL1B, CD14, HLA-DRB1, IL6
408.4IL10, TGFB1, CD14, TNF, HLA-DRB1
41
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8.4IL1B, IL10, IL6, TNF, TGFB1
42
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8.2HLA-DRB1, IL8, IL1B, IL6, TNF, ICAM1
43
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8.2TNF, IL6, IL1B, IL10, ICAM1, HLA-DRB1
44
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8.2CXCL2, IL8, TNF, IL6, IL1B
458.1CXCL2, IL1B, IL6, TNF, ICAM1
46
Hide members
8.0HLA-DRB1, IL6, IL1B, CD79A, CD14, IGHE
478.0IL8, IL1B, CXCL2, ICAM1, CD14, TNF
487.7IL1B, MPO, ALB, TNF, ICAM1, IL6
497.5IL1B, TNF, CXCL2, TGFB1, IL6, ICAM1
50
Hide members
7.3TGFB1, IL6, IL1B, IL8, IL10, TNF

Compounds for genes affiliated with Extrinsic Allergic Alveolitis

Sources:
45Novoseek, 11DrugBank, 2BitterDB, 60Tocris Bioscience, 29IUPHAR, 50PharmGKB, 24HMDB
See all sources

Compounds related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show top 50)    (show all 253)
idCompoundScoreTop Affiliating Genes
1cycloheximide4510.6SOD2
2pentoxifylline45 1111.4CD14, MPO
3ulinastatin4510.1ICAM1, MPO, HP
4ivig4510.0CD79A, IGHE
5hydrocortisone45 2 60 1112.8IL8, IGHE, FCER2
6endotoxin459.8CXCL2, ICAM1
7okt3459.6IL6, IL10, ICAM1, FCER2
8gm-csf45 2910.6ICAM1, TNF, CD14, IL10
9prednisolone45 29 1111.5SFTPD, MPO, IGHE, CD14, CD79A
10pge2459.4TGFB1, CXCL2
11cyclosporin a45 29 6011.3ICAM1, IGHE, CD14, CD79A, HP
12diphenyleneiodonium459.2SOD2, SOD1, MPO, IL1B, TGFB1
13allergens459.1FCER2, HLA-DRB1, IL10, IGHE, SFTPD
14taurine chloramine459.0IL6, IL1B, IL8, MPO, TNF
15mip 1alpha458.9TNF, IL6, IL8, IL10, IL1B
16gold sodium thiomalate458.9IL1B, IL8, CD14, HLA-DRB1, TNF
17lipoteichoic acid458.8CD14, IL8, IL1B, IL10, TNF, IL6
18pdtc458.8SOD2, SOD1, IL8, IL1B, IL6, TGFB1
19triptolide458.8CD14, TNF, IL8, IL1B, ICAM1, IL6
20sulfasalazine45 29 50 1111.7HP, IL8, IL1B, CD79A, MPO, TNF
21il-12458.7TNF, IL10, IL8, IL1B, IL6
22vitamin d458.7IL6, IGHE, CD14, CD79A, HP, IL10
23polymyxin b458.6TNF, CD14, IL8, IL1B, IL6, ICAM1
24peptidoglycan45 299.6IL10, CD14, IL1B, TNF, IL8, IL6
255 aminosalicylic acid458.6MPO, TNF, IL8, IL10, IL1B
26budesonide45 50 1110.5IGHE, IL8, IL1B, MPO, TNF, ICAM1
27methacholine45 119.4ICAM1, MPO, IGHE, CD14, CD79A, IL8
288-isoprostane458.3SOD1, ICAM1, TNF, MPO, HP, IL10
29il 10458.3IL6, TGFB1, IL1B, IL8, IL10, TNF
30creatinine458.2HP, ALB, TGFB1, CD79A, CD14, IGHE
31herbimycin a45 609.2CD14, FCER2, ICAM1, TNF, IL8, IL1B
32groalpha458.0IL6, IL1B, ICAM1, TNF, CXCL2, IL8
33neopterin457.9HP, IL10, IL8, IL1B, FCER2, CD79A
34ascorbic acid45 248.9IGHE, SOD2, MPO, ICAM1, HP, ALB
35ccl345 298.9TNF, IL6, IL1B, IL8, IL10, ICAM1
36tarc457.9IL8, IL10, CXCL2, TNF, IGHE, ICAM1
37calcitriol45 60 11 2410.7ALB, IL6, IL1B, IL10, CD14, TNF
38rantes457.6ICAM1, CD14, CXCL2, IL1B, IL6, TGFB1
39sp 60012545 608.5TNF, ICAM1, IL1B, IL6, TGFB1, IL8
40dexamethasone45 50 29 1110.5FCER2, SFTPD, SOD2, IGHE, CD14, CXCL2
41actinomycin d457.3SOD2, TNF, IGHE, HP, IL8, IL1B
42hyaluronic acid45 248.3IL6, ALB, TGFB1, IL1B, IL8, HP
43sb 20358045 608.1TGFB1, IL6, IL1B, IL8, IL10, CXCL2
44methotrexate45 50 119.0ALB, TGFB1, SOD2, TNF, HLA-DRB1, IGHE
45ly294002456.9TNF, TGFB1, IL6, IL8, IL10, CXCL2
46n acetylcysteine456.7ICAM1, TNF, MPO, IGHE, CD79A, CXCL2
47nitric oxide45 11 248.6FCER2, IL6, IL1B, IL8, IL10, CXCL2
48histamine45 29 248.2IL6, FCER2, ALB, TGFB1, IL1B, IL8
49vegf455.7IGHE, CD79A, HP, CXCL2, IL10, IL8
50lactate455.2MPO, SFTPD, SOD2, SOD1, TGFB1, ALB

GO Terms for genes affiliated with Extrinsic Allergic Alveolitis

Sources:
16Gene Ontology
See all sources

Cellular components related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098978.3TNF, HLA-DRB1, CD79A, IL6, FCER2, ICAM1
2extracellular spaceGO:0056155.2TGFB1, SFTPD, SOD1, ICAM1, TNF, MPO
3extracellular regionGO:0055765.2CD14, IGHE, TNF, SOD1, SFTPD, HP

Biological processes related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show all 45)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of cytokine secretion involved in immune responseGO:00274010.5IL10
2response to superoxideGO:00030310.2SOD2, SOD1
3removal of superoxide radicalsGO:01943010.1SOD2, SOD1, MPO
4positive regulation of humoral immune response mediated by circulating immunoglobulinGO:00292510.1FCER2, TNF
5receptor biosynthetic processGO:03280010.0TNF, IL10
6positive regulation of calcidiol 1-monooxygenase activityGO:06055910.0TNF, IL1B
7response to hydrogen peroxideGO:04254210.0SOD2, SOD1, HP
8sequestering of triglycerideGO:03073010.0TNF, IL1B
9positive regulation of heterotypic cell-cell adhesionGO:03411610.0IL1B, TNF
10positive regulation of fever generationGO:03162210.0TNF, IL1B
11hydrogen peroxide biosynthetic processGO:05066510.0SOD1, SOD2
12response to heatGO:0094089.9SOD1, CD14, IL6
13positive regulation of cytokine secretionGO:0507159.9IL10, CD14, TNF
14response to activityGO:0148239.8SOD2, TNF, IL10
15negative regulation of growth of symbiont in hostGO:0441309.8IL10, MPO, TNF
16negative regulation of lipid storageGO:0108889.8IL6, TNF
17cellular response to lipopolysaccharideGO:0712229.8ICAM1, CD14, IL10, IL8
18epithelial cell proliferation involved in salivary gland morphogenesisGO:0606649.8IL6, TNF
19positive regulation of chemokine biosynthetic processGO:0450809.8IL1B, TNF
20positive regulation of superoxide anion generationGO:0329309.7TGFB1, SOD1
21positive regulation of interleukin-6 productionGO:0327559.6TNF, IL1B, IL6
22regulation of I-kappaB kinase/NF-kappaB cascadeGO:0431229.6TNF, IL1B
23response to molecule of bacterial originGO:0022379.5IL8, IL10, CXCL2
24response to glucocorticoid stimulusGO:0513849.5TNF, IL10, IL6
25lipopolysaccharide-mediated signaling pathwayGO:0316639.4TGFB1, IL1B, TNF
26cellular response to organic cyclic compoundGO:0714079.4TNF, IL1B, TGFB1
27protein kinase B signaling cascadeGO:0434919.4TGFB1, IL1B, TNF
28positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.4TNF, IL10, IL1B, IL6
29negative regulation of T cell proliferationGO:0421309.4TGFB1, IL10, HLA-DRB1, SFTPD
30MAPK cascadeGO:0001659.3TGFB1, IL1B, TNF
31positive regulation of peptidyl-serine phosphorylationGO:0331389.3TNF, IL6, TGFB1
32cytokine-mediated signaling pathwayGO:0192219.3ICAM1, HLA-DRB1, IL1B, IL6
33positive regulation of nitric oxide biosynthetic processGO:0454299.2SOD2, ICAM1, TNF, IL1B, IL6
34negative regulation of fat cell differentiationGO:0455999.2SOD2, TNF, IL6, TGFB1
35positive regulation of protein kinase B signaling cascadeGO:0518979.1TNF, IL6, TGFB1
36platelet degranulationGO:0025769.1TGFB1, ALB, SOD1
37positive regulation of protein phosphorylationGO:0019349.0TGFB1, IL1B, TNF
38platelet activationGO:0301689.0SOD1, IL6, ALB, TGFB1
39positive regulation of NF-kappaB transcription factor activityGO:0510928.8ICAM1, TNF, IL1B, IL6, TGFB1
40negative regulation of cell proliferationGO:0082858.6TGFB1, IL6, IL1B, IL8, TNF, SOD2
41positive regulation of transcription, DNA-dependentGO:0458938.6TGFB1, IL6, IL1B, IL10, TNF
42immune responseGO:0069558.5IL1B, IL8, CXCL2, IGHE, HLA-DRB1
43positive regulation of apoptotic processGO:0430658.3TGFB1, IL6, TNF, SOD1
44response to drugGO:0424938.2SOD2, SOD1, ICAM1, TNF, IL10, IL6
45inflammatory responseGO:0069547.5TGFB1, TNF, CD14, CXCL2, IL10, IL8

Molecular functions related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1superoxide dismutase activityGO:0047849.9SOD1, SOD2
2cytokine activityGO:0051258.7IL6, IL1B, IL10, TNF

Products for genes affiliated with Extrinsic Allergic Alveolitis

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Sources for Extrinsic Allergic Alveolitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet