HP
MCID: EXT034
MIFTS: 65

Extrinsic Allergic Alveolitis (HP) malady

Respiratory diseases, Immune diseases categories

Summaries for Extrinsic Allergic Alveolitis

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss.

MalaCards: Extrinsic Allergic Alveolitis, also known as hypersensitivity pneumonitis, is related to sarcoidosis and allergic asthma. An important gene associated with Extrinsic Allergic Alveolitis is SFTPD (surfactant protein D), and among its related pathways are B cell receptor signaling pathway and Senescence and Autophagy. The compounds cycloheximide and pentoxifylline have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and monocytes, and related mouse phenotypes are vision/eye and nervous system.

Wikipedia:63 Hypersensitivity pneumonitis (HP; also called extrinsic allergic alveolitis, EAA) is an inflammation of... more...

Aliases & Classifications for Extrinsic Allergic Alveolitis

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8Disease Ontology, 48Orphanet, 60UMLS, 42NIH Rare Diseases, 44Novoseek, 56SNOMED-CT, 27ICD9CM, 39NCIt, 34MeSH, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet, 35MESH via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases, Immune diseases


Characteristics (Orphanet epidemiological data):

48
extrinsic allergic alveolitis:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

extrinsic allergic alveolitis 8 48 60
hypersensitivity pneumonitis 8 42 48
alveolitis 8 44 60
extrinsic allergic pneumonia hypersensitivity pneumonitis 42
allergic interstitial pneumonitis 42
alveolitis, extrinsic allergic 42
pneumonitis hypersensitivity 44
allergic pneumonitis 42
hp 48


External Ids:

Disease Ontology8 DOID:841
ICD9CM27 495.9, 495
NCIt39 C34369
MeSH34 D000542
ICD10 via Orphanet26 J67.0, J67.2, J67.3 J67.4, J67.5, J67.6, J67.7, J67.8, J67.9, J67.1, more
SNOMED-CT via Orphanet57 37471005
UMLS via Orphanet61 C0002390
MESH via Orphanet35 D000542
ICD1025 J67, J67.8, J67.9

Related Diseases for Extrinsic Allergic Alveolitis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Extrinsic Allergic Alveolitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 482)
idRelated DiseaseScoreTop Affiliating Genes
1sarcoidosis31.1FCER2, IL1B, CD14, HLA-DRB1, TNF, ICAM1
2allergic asthma30.7FCER2, IL8, IL10, CD14, IGHE, ICAM1
3pulmonary fibrosis30.7TGFB1, IL1B, IL8, MPO, SOD1, SFTPD
4asthma30.7TGFB1, FCER2, IL1B, IL8, IL10, CD79A
5idiopathic pulmonary fibrosis30.6TGFB1, IL1B, IL8, SFTPD
6hypertension30.6TGFB1, ALB, CD79A, ICAM1
7pneumonia30.6TGFB1, IL6, IL1B, IL8, IL10, CXCL2
8celiac disease30.4CD79A
9aspergillosis30.4CD79A, SFTPD
10allergic bronchopulmonary aspergillosis30.4IGHE, SFTPD
11interstitial lung disease30.4TGFB1, IL8, SFTPD
12cork-handlers' disease30.4ALB, IL8, MPO, SOD2
13pulmonary sarcoidosis30.4TNF, ICAM1, SFTPD
14psoriatic arthritis30.4IL1B, HLA-DRB1, TNF
15arthritis30.4IL6, IL1B, IL8, TNF
16atherosclerosis30.3TGFB1, ALB, IL6, IL1B, IL8, IL10
17malaria30.2ALB, FCER2, IL10, HP, HLA-DRB1, TNF
18crohn's disease30.2ALB, TNF
19pulmonary tuberculosis30.2IL10, HP, CD14, HLA-DRB1
20plasmodium falciparum malaria30.2IL10, HP, HLA-DRB1, ICAM1
21type 1 diabetes30.2ALB, IL1B, CD79A, HLA-DRB1
22eosinophilia30.1FCER2, IL8, IL10, CD79A, CD14, IGHE
23sickle cell disease30.1HP
24hemochromatosis30.1HP
25acute poststreptococcal glomerulonephritis30.1CD79A
26hellp syndrome30.1HP
27hemoglobinuria30.1HP
28cholangitis30.1ALB
29autoimmune hemolytic anemia30.1HP, CD79A
30protein-energy malnutrition30.1ALB
31polymyalgia rheumatica30.1HLA-DRB1
32mastitis30.1ALB, IL1B, IL8, HP
33coronary artery disease30.1IL6, HP, CD14, ICAM1
34diabetic nephropathy30.1TGFB1, ALB, HP, SOD2
35ischemia30.1CXCL2, HP, CD14, MPO, ICAM1, SOD1
36hepatitis30.1TGFB1, ALB, HLA-DRB1
37liver cirrhosis30.1TGFB1, ALB, CD14, HLA-DRB1
38bronchiolitis obliterans30.0IL8
39bronchiolitis30.0FCER2, IL8, IGHE
40juvenile rheumatoid arthritis30.0IL6, HLA-DRB1, TNF
41diabetes mellitus30.0TGFB1, ALB, IL6, IL1B, HP, CD79A
42myositis30.0ICAM1
43purpura30.0CD79A
44pulmonary eosinophilia30.0IL8, IGHE, SFTPD
45multiple myeloma30.0IL6
46rheumatoid arthritis30.0FCER2, IL6, IL1B, IL8, IL10, HP
47colorectal cancer30.0TGFB1, CD14
48ovarian cancer30.0TGFB1, HP
49schizophrenia30.0CD14, HLA-DRB1
50lung cancer30.0TGFB1, ALB

Graphical network of the top 20 diseases related to Extrinsic Allergic Alveolitis:



Diseases related to extrinsic allergic alveolitis

Clinical Features for Extrinsic Allergic Alveolitis

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Drugs & Therapeutics for Extrinsic Allergic Alveolitis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Extrinsic Allergic Alveolitis

Search NIH Clinical Center for Extrinsic Allergic Alveolitis

Search CenterWatch for Extrinsic Allergic Alveolitis

Genetic Tests for Extrinsic Allergic Alveolitis

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Anatomical Context for Extrinsic Allergic Alveolitis

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32MalaCards
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MalaCards organs/tissues related to Extrinsic Allergic Alveolitis:

32
Lung, Testes, Monocytes, Skin, Myeloid, T cells, Nk cells

Animal Models for Extrinsic Allergic Alveolitis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Extrinsic Allergic Alveolitis:

36 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053919.6SOD1, SOD2
2MP:00036319.5SOD1, TGFB1
3MP:00053699.3ICAM1, TGFB1, SOD1
4MP:00053859.0SOD2, IL1B, IL10, HP, MPO, SOD1
5MP:00053768.2HP, CD79A, IGHE, ICAM1, SOD1, FCER2
6MP:00053817.7TGFB1, ALB, FCER2, IL6, TNF, ICAM1
7MP:00020067.6TNF, HP, IL10, ICAM1, IL1B, IL6
8MP:00053707.6SOD2, SOD1, TNF, HP, IL10, IL6
9MP:00053847.0SOD2, SOD1, ICAM1, TNF, CD79A, HP
10MP:00107686.2SOD1, SFTPD, TGFB1, ALB, SOD2, IL6
11MP:00053976.1SOD2, SOD1, ICAM1, TNF, MPO, IGHE
12MP:00053875.6IGHE, ICAM1, HP, CD79A, SFTPD, SOD2

Publications for Extrinsic Allergic Alveolitis

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50PubMed
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Articles related to Extrinsic Allergic Alveolitis:

(show top 50)    (show all 158)
idTitleAuthorsYear
1
Linear and nonlinear analysis of base lung sound in extrinsic allergic alveolitis patients in comparison to healthy subjects. (23591730)
2013
2
Role of interleukin 4 and its receptor in clinical presentation of chronic extrinsic allergic alveolitis: a pilot study. (23721656)
2013
3
Extrinsic allergic alveolitis: incidence and mortality in the general population. (17307752)
2007
4
Extrinsic allergic alveolitis with eosinophil infiltration induced by 1,1,1,2-tetrafluoroethane (HFC-134a): a case report. (17827848)
2007
5
Cockade-like structures in alveolar macrophages in extrinsic allergic alveolitis - another piece in the puzzle? (15753631)
2005
6
Preliminary study on effect of pentoxifylline in treatment of extrinsic allergic alveolitis]. (15061967)
2004
7
Extrinsic allergic alveolitis: inhibitory effects of pentoxifylline on cytokine production by alveolar macrophages. (14989392)
2004
8
Extrinsic allergic alveolitis in practice. (15114816)
2004
9
Blood myeloid and lymphoid dendritic cells reflect Th1/Th2 balance in sarcoidosis and extrinsic allergic alveolitis. (15314973)
2003
10
IgG antibodies typical for extrinsic allergic alveolitis--an inter-laboratory quality assessment. (11726311)
2001
11
Pet-fish food lung- a new form of extrinsic allergic alveolitis. (10756166)
2000
12
Effects of erythromycin on experimental extrinsic allergic alveolitis. (10051731)
1999
13
Aerobiological analysis in a salami factory: a possible case of extrinsic allergic alveolitis by Penicillium camembertii. (10421864)
1999
14
Clozapine-induced extrinsic allergic alveolitis. (9926066)
1998
15
Lung and blood T-cell receptor repertoire in extrinsic allergic alveolitis. (9150312)
1997
16
Experimental extrinsic allergic alveolitis and pulmonary angiitis induced by intratracheal or intravenous challenge with Corynebacterium parvum in sensitized rats. (8863677)
1996
17
Air-trapping in extrinsic allergic alveolitis on computed tomography. (8893635)
1996
18
Relationship between plasma cell levels and profile of bronchoalveolar lavage fluid in patients with subacute extrinsic allergic alveolitis. (8105558)
1993
19
A role for IgE in extrinsic allergic alveolitis? (1387827)
1992
20
Radiographic grading of extrinsic allergic alveolitis. A comparison between a modified ILO classification and a descriptive method. (1742127)
1991
21
Provocation tests in extrinsic allergic alveolitis in mushroom workers. (2030812)
1991
22
Effect of smoking on the lipid composition of lung lining fluid and relationship between immunostimulatory lipids, inflammatory cells and foamy macrophages in extrinsic allergic alveolitis. (2090475)
1990
23
Extrinsic allergic alveolitis caused by esparto (Stipa tenacissima). (2088103)
1990
24
Reversible pulmonary arterial hypertension in a 6-year-old girl with extrinsic allergic alveolitis. (2919518)
1989
25
Current concepts on bronchoalveolar lavage cells in extrinsic allergic alveolitis. (3068746)
1988
26
Farmers' lung and extrinsic allergic alveolitis. (3684935)
1987
27
Bronchoalveolar lavage in extrinsic allergic alveolitis. (3322873)
1987
28
Lymphocyte subpopulations in extrinsic allergic alveolitis. (3488003)
1986
29
A current view of pigeon fancier's lung. A model for pulmonary extrinsic allergic alveolitis. (6754135)
1982
30
Extrinsic allergic alveolitis--management of established cases. (6962073)
1982
31
Hypersensitivity penumonitis (extrinsic allergic alveolitis). (7028022)
1981
32
Sarcoidosis or extrinsic allergic alveolitis? (7313339)
1981
33
Extrinsic allergic alveolitis caused by pigeon breeding at a high altitude (2,240 meters). Hemodynamic behavior of pulmonary circulation. (7305116)
1981
34
Sawmill work and extrinsic allergic alveolitis. (6937828)
1980
35
Site and type of impaired lung function in extrinsic allergic alveolitis. (7394349)
1980
36
Extrinsic allergic alveolitis in a sawmill worker. A case report. (7001618)
1980
37
Asthma and extrinsic allergic alveolitis due to Merulius lacrymans. (709798)
1978
38
Antigens implicated in the pathogenesis of extrinsic allergic alveolitis. (416062)
1978
39
Mechanical properties of the lung in extrinsic allergic alveolitis. (684667)
1978
40
Basics of pulmonary immunology and hypersensitivity pneumonitis (extrinsic allergic alveolitis) [proceedings]. (585681)
1977
41
Immunologically mediated lung diseases. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis. (944440)
1976
42
Extrinsic allergic alveolitis in Scottish maltworkers. (1252813)
1976
43
Extrinsic allergic alveolitis after Aspergillus fumigatus inhalation. Evidence of a type IV immunologic pathogenesis. (795300)
1976
44
Letter: Extrinsic allergic alveolitis. (953591)
1976
45
Extrinsic allergic alveolitis owing to hypersensitivity to chickens-significance of sputum precipitins. (4209494)
1974
46
Letter: Extrinsic allergic alveolitis. (4419926)
1974
47
Lesions experimentally produced by fungi implicated in extrinsic allergic alveolitis. (4531447)
1974
48
Extrinsic allergic alveolitis. (4492994)
1973
49
A bovine disease similar to farmer's lung: extrinsic allergic alveolitis. (4252199)
1971
50
Coffee worker's lung. A new example of extrinsic allergic alveolitis. (4922066)
1970

Genetic Variations for Extrinsic Allergic Alveolitis

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Expression for genes affiliated with Extrinsic Allergic Alveolitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Extrinsic Allergic Alveolitis

Search GEO for disease gene expression data for Extrinsic Allergic Alveolitis.

Pathways for genes affiliated with Extrinsic Allergic Alveolitis

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29KEGG, 37NCBI BioSystems Database, 52R&D Systems, 51QIAGEN, 53Reactome, 12EMD Millipore
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Pathways related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show top 50)    (show all 54)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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10.2CD79A
210.2IL8
310.2IL1B
410.1SOD1
5
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10.1IL6
6
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10.0HLA-DRB1
79.9SOD1, SOD2
8
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9.7CXCL2
9
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9.6SOD2, SOD1, IL8
109.6IL6, IL8, CD14
119.5IL8, IL6, IL1B
129.5IGHE, FCER2, IL10
139.4ICAM1, HLA-DRB1, IL10
149.4IL1B, IL8, IL10, CD14
159.4CD14, IL8, MPO, IL6
169.4SFTPD, CD14, MPO, HLA-DRB1
179.2IL10, ICAM1, HLA-DRB1, FCER2
18
Hide members
9.2CD14, CXCL2, SOD2
199.2HLA-DRB1, CXCL2
209.1ICAM1, IL1B, MPO, TNF
21
Hide members
9.0CXCL2, TGFB1
229.0TNF, ICAM1, IL6, IL8
238.9CXCL2, IL1B, IL8, CD14
24
Hide members
8.8TNF, CD14, IL8, IL1B, IL6
25
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8.8IL8, IL1B, IL6, CD14, TNF
268.8IL6, ICAM1, TNF, MPO, HP
278.8IL1B, IL10, CD14, TNF, IL6
288.7IL1B, IL6, TNF, IL10, IL8
298.7IL6, IL10, IL8, IL1B, TNF
30
Cytokine production by Th17 cells in CF (Mouse model)
8.7IL8, TGFB1, IL6, CD14, ICAM1
318.7TNF, IL1B, IL6, ICAM1, IL10
32
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8.7IGHE, FCER2, CD79A, ICAM1, TNF
33
Immune response Bacterial infections in normal airways
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8.6SFTPD, TNF, IL8, IL1B, IL6, CD14
34
Development PDGF signaling via STATs and NF-kB
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8.5TNF, MPO, CD14, IL10, IL1B, IL6
35
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8.5TNF, HLA-DRB1, CD14, CD79A, FCER2, IL1B
36
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8.5IL6, IL1B, IL8, TNF, CD14, IL10
378.5CD14, IL1B, IL8, IL10, IL6, TNF
388.5CXCL2, IL8, IL6, IL1B, CD14
398.4FCER2, TNF, IL1B, CD14, HLA-DRB1, IL6
408.4IL10, TGFB1, CD14, TNF, HLA-DRB1
41
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8.4IL1B, IL10, IL6, TNF, TGFB1
42
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8.2HLA-DRB1, IL8, IL1B, IL6, TNF, ICAM1
43
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8.2TNF, IL6, IL1B, IL10, ICAM1, HLA-DRB1
44
Hide members
8.2CXCL2, IL8, TNF, IL6, IL1B
458.1CXCL2, IL1B, IL6, TNF, ICAM1
46
Hide members
8.0HLA-DRB1, IL6, IL1B, CD79A, CD14, IGHE
478.0IL8, IL1B, CXCL2, ICAM1, CD14, TNF
487.7IL1B, MPO, ALB, TNF, ICAM1, IL6
497.5IL1B, TNF, CXCL2, TGFB1, IL6, ICAM1
50
Hide members
7.3TGFB1, IL6, IL1B, IL8, IL10, TNF

Compounds for genes affiliated with Extrinsic Allergic Alveolitis

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Sources:
44Novoseek, 11DrugBank, 2BitterDB, 59Tocris Bioscience, 28IUPHAR, 49PharmGKB, 24HMDB
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Compounds related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show top 50)    (show all 253)
idCompoundScoreTop Affiliating Genes
1cycloheximide4410.6SOD2
2pentoxifylline44 1111.4CD14, MPO
3ulinastatin4410.1ICAM1, MPO, HP
4ivig4410.0CD79A, IGHE
5hydrocortisone44 2 59 1112.8IL8, IGHE, FCER2
6endotoxin449.8CXCL2, ICAM1
7okt3449.6IL6, IL10, ICAM1, FCER2
8gm-csf44 2810.6ICAM1, TNF, CD14, IL10
9prednisolone44 28 1111.5SFTPD, MPO, IGHE, CD14, CD79A
10pge2449.4TGFB1, CXCL2
11cyclosporin a44 28 5911.3ICAM1, IGHE, CD14, CD79A, HP
12diphenyleneiodonium449.2SOD2, SOD1, MPO, IL1B, TGFB1
13allergens449.1FCER2, HLA-DRB1, IL10, IGHE, SFTPD
14taurine chloramine449.0IL6, IL1B, IL8, MPO, TNF
15mip 1alpha448.9TNF, IL6, IL8, IL10, IL1B
16gold sodium thiomalate448.9IL1B, IL8, CD14, HLA-DRB1, TNF
17lipoteichoic acid448.8CD14, IL8, IL1B, IL10, TNF, IL6
18pdtc448.8SOD2, SOD1, IL8, IL1B, IL6, TGFB1
19triptolide448.8CD14, TNF, IL8, IL1B, ICAM1, IL6
20sulfasalazine44 28 49 1111.7HP, IL8, IL1B, CD79A, MPO, TNF
21il-12448.7TNF, IL10, IL8, IL1B, IL6
22vitamin d448.7IL6, IGHE, CD14, CD79A, HP, IL10
23polymyxin b448.6TNF, CD14, IL8, IL1B, IL6, ICAM1
24peptidoglycan44 289.6IL10, CD14, IL1B, TNF, IL8, IL6
255 aminosalicylic acid448.6MPO, TNF, IL8, IL10, IL1B
26budesonide44 49 1110.5IGHE, IL8, IL1B, MPO, TNF, ICAM1
27methacholine44 119.4ICAM1, MPO, IGHE, CD14, CD79A, IL8
288-isoprostane448.3SOD1, ICAM1, TNF, MPO, HP, IL10
29il 10448.3IL6, TGFB1, IL1B, IL8, IL10, TNF
30creatinine448.2HP, ALB, TGFB1, CD79A, CD14, IGHE
31herbimycin a44 599.2CD14, FCER2, ICAM1, TNF, IL8, IL1B
32groalpha448.0IL6, IL1B, ICAM1, TNF, CXCL2, IL8
33neopterin447.9HP, IL10, IL8, IL1B, FCER2, CD79A
34ascorbic acid44 248.9IGHE, SOD2, MPO, ICAM1, HP, ALB
35ccl344 288.9TNF, IL6, IL1B, IL8, IL10, ICAM1
36tarc447.9IL8, IL10, CXCL2, TNF, IGHE, ICAM1
37calcitriol44 59 11 2410.7ALB, IL6, IL1B, IL10, CD14, TNF
38rantes447.6ICAM1, CD14, CXCL2, IL1B, IL6, TGFB1
39sp 60012544 598.5TNF, ICAM1, IL1B, IL6, TGFB1, IL8
40dexamethasone44 49 28 1110.5FCER2, SFTPD, SOD2, IGHE, CD14, CXCL2
41actinomycin d447.3SOD2, TNF, IGHE, HP, IL8, IL1B
42hyaluronic acid44 248.3IL6, ALB, TGFB1, IL1B, IL8, HP
43sb 20358044 598.1TGFB1, IL6, IL1B, IL8, IL10, CXCL2
44methotrexate44 49 119.0ALB, TGFB1, SOD2, TNF, HLA-DRB1, IGHE
45ly294002446.9TNF, TGFB1, IL6, IL8, IL10, CXCL2
46n acetylcysteine446.7ICAM1, TNF, MPO, IGHE, CD79A, CXCL2
47nitric oxide44 11 248.6FCER2, IL6, IL1B, IL8, IL10, CXCL2
48histamine44 28 248.2IL6, FCER2, ALB, TGFB1, IL1B, IL8
49vegf445.7IGHE, CD79A, HP, CXCL2, IL10, IL8
50lactate445.2MPO, SFTPD, SOD2, SOD1, TGFB1, ALB

GO Terms for genes affiliated with Extrinsic Allergic Alveolitis

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Sources:
16Gene Ontology
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Cellular components related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098978.3TNF, HLA-DRB1, CD79A, IL6, FCER2, ICAM1
2extracellular spaceGO:0056155.2IL1B, TGFB1, IL6, IL8, IL10, CXCL2
3extracellular regionGO:0055765.2TGFB1, SFTPD, ALB, FCER2, IL6, IL1B

Biological processes related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show all 45)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of cytokine secretion involved in immune responseGO:00274010.5IL10
2response to superoxideGO:00030310.2SOD2, SOD1
3removal of superoxide radicalsGO:01943010.1SOD2, SOD1, MPO
4positive regulation of humoral immune response mediated by circulating immunoglobulinGO:00292510.1FCER2, TNF
5receptor biosynthetic processGO:03280010.0TNF, IL10
6positive regulation of calcidiol 1-monooxygenase activityGO:06055910.0TNF, IL1B
7response to hydrogen peroxideGO:04254210.0SOD2, SOD1, HP
8sequestering of triglycerideGO:03073010.0TNF, IL1B
9positive regulation of heterotypic cell-cell adhesionGO:03411610.0IL1B, TNF
10positive regulation of fever generationGO:03162210.0TNF, IL1B
11hydrogen peroxide biosynthetic processGO:05066510.0SOD1, SOD2
12response to heatGO:0094089.9SOD1, CD14, IL6
13positive regulation of cytokine secretionGO:0507159.9IL10, CD14, TNF
14response to activityGO:0148239.8SOD2, TNF, IL10
15negative regulation of growth of symbiont in hostGO:0441309.8IL10, MPO, TNF
16negative regulation of lipid storageGO:0108889.8IL6, TNF
17cellular response to lipopolysaccharideGO:0712229.8ICAM1, CD14, IL10, IL8
18epithelial cell proliferation involved in salivary gland morphogenesisGO:0606649.8IL6, TNF
19positive regulation of chemokine biosynthetic processGO:0450809.8IL1B, TNF
20positive regulation of superoxide anion generationGO:0329309.7TGFB1, SOD1
21positive regulation of interleukin-6 productionGO:0327559.6TNF, IL1B, IL6
22regulation of I-kappaB kinase/NF-kappaB cascadeGO:0431229.6TNF, IL1B
23response to molecule of bacterial originGO:0022379.5IL8, IL10, CXCL2
24response to glucocorticoid stimulusGO:0513849.5TNF, IL10, IL6
25lipopolysaccharide-mediated signaling pathwayGO:0316639.4TGFB1, IL1B, TNF
26cellular response to organic cyclic compoundGO:0714079.4TNF, IL1B, TGFB1
27protein kinase B signaling cascadeGO:0434919.4TGFB1, IL1B, TNF
28positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.4TNF, IL10, IL1B, IL6
29negative regulation of T cell proliferationGO:0421309.4TGFB1, IL10, HLA-DRB1, SFTPD
30MAPK cascadeGO:0001659.3TGFB1, IL1B, TNF
31positive regulation of peptidyl-serine phosphorylationGO:0331389.3TNF, IL6, TGFB1
32cytokine-mediated signaling pathwayGO:0192219.3ICAM1, HLA-DRB1, IL1B, IL6
33positive regulation of nitric oxide biosynthetic processGO:0454299.2SOD2, ICAM1, TNF, IL1B, IL6
34negative regulation of fat cell differentiationGO:0455999.2SOD2, TNF, IL6, TGFB1
35positive regulation of protein kinase B signaling cascadeGO:0518979.1TNF, IL6, TGFB1
36platelet degranulationGO:0025769.1TGFB1, ALB, SOD1
37positive regulation of protein phosphorylationGO:0019349.0TGFB1, IL1B, TNF
38platelet activationGO:0301689.0SOD1, IL6, ALB, TGFB1
39positive regulation of NF-kappaB transcription factor activityGO:0510928.8ICAM1, TNF, IL1B, IL6, TGFB1
40negative regulation of cell proliferationGO:0082858.6TGFB1, IL6, IL1B, IL8, TNF, SOD2
41positive regulation of transcription, DNA-dependentGO:0458938.6TGFB1, IL6, IL1B, IL10, TNF
42immune responseGO:0069558.5IL1B, IL8, CXCL2, IGHE, HLA-DRB1
43positive regulation of apoptotic processGO:0430658.3TGFB1, IL6, TNF, SOD1
44response to drugGO:0424938.2SOD2, SOD1, ICAM1, TNF, IL10, IL6
45inflammatory responseGO:0069547.5TGFB1, TNF, CD14, CXCL2, IL10, IL8

Molecular functions related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1superoxide dismutase activityGO:0047849.9SOD1, SOD2
2cytokine activityGO:0051258.7IL6, IL1B, IL10, TNF

Products for genes affiliated with Extrinsic Allergic Alveolitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Extrinsic Allergic Alveolitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet