HP
MCID: EXT034
MIFTS: 65

Extrinsic Allergic Alveolitis (HP) malady

Rare diseases, Respiratory diseases, Immune diseases categories
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Summaries for Extrinsic Allergic Alveolitis

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8Disease Ontology, 65Wikipedia, 33MalaCards
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Disease Ontology:8 An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss.

MalaCards: Extrinsic Allergic Alveolitis, also known as hypersensitivity pneumonitis, is related to sarcoidosis and pulmonary fibrosis. An important gene associated with Extrinsic Allergic Alveolitis is FCER2 (Fc fragment of IgE, low affinity II, receptor for (CD23)), and among its related pathways are superoxide radicals degradation and IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types. The compounds taurine chloramine and allergens have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and monocytes, and related mouse phenotypes are skeleton and digestive/alimentary.

Wikipedia:65 Hypersensitivity pneumonitis (HP; also called extrinsic allergic alveolitis, EAA) is an inflammation of... more...

Aliases & Classifications for Extrinsic Allergic Alveolitis

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8Disease Ontology, 43NIH Rare Diseases, 45Novoseek, 49Orphanet, 62UMLS, 58SNOMED-CT, 35MeSH, 27ICD9CM, 40NCIt, 26ICD10 via Orphanet, 59SNOMED-CT via Orphanet, 63UMLS via Orphanet, 36MESH via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Respiratory diseases, Immune diseases


Characteristics (Orphanet epidemiological data):

49
extrinsic allergic alveolitis:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

extrinsic allergic alveolitis 8 49 62
hypersensitivity pneumonitis 8 43 49
alveolitis 8 45 62
extrinsic allergic pneumonia hypersensitivity pneumonitis 43
allergic interstitial pneumonitis 43
alveolitis, extrinsic allergic 43
pneumonitis hypersensitivity 45
allergic pneumonitis 43
hp 49


External Ids:

Disease Ontology8 DOID:841
MeSH35 D000542
ICD9CM27 495, 495.9
NCIt40 C34369
ICD10 via Orphanet26 J67.0, J67.2, J67.3 J67.4, J67.5, J67.6, J67.7, J67.8, J67.9, J67.1, more
SNOMED-CT via Orphanet59 37471005
UMLS via Orphanet63 C0002390
MESH via Orphanet36 D000542
ICD1025 J67, J67.8, J67.9

Related Diseases for Extrinsic Allergic Alveolitis

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17GeneCards, 18GeneDecks
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Diseases related to Extrinsic Allergic Alveolitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 280)
idRelated DiseaseScoreTop Affiliating Genes
1sarcoidosis31.1CD14, IL1B, ICAM1, FCER2, TNF, SFTPD
2pulmonary fibrosis30.8IL1B, IL8, SOD1, MPO, SFTPD
3idiopathic pulmonary fibrosis30.8IL1B, IL8, SFTPD
4hypertension30.6CD79A, ALB, ICAM1
5allergic bronchopulmonary aspergillosis30.6SFTPD, IGHE
6aspergillosis30.6CD79A, SFTPD
7pulmonary sarcoidosis30.5ICAM1, TNF, SFTPD
8asthma30.5CD79A, CD14, IL1B, IL8, IL10, ICAM1
9interstitial lung disease30.5CD79A, IL1B, TNF, SFTPD
10hemoglobinuria30.5HP
11coronary artery disease30.5HP, SOD1, SOD2
12cork-handlers' disease30.4ALB, IL8, SOD2, MPO
13autoimmune hemolytic anemia30.4CD79A, HP
14arthritis30.4IL1B, IL6, IL8, TNF
15pulmonary tuberculosis30.4CD14, HP, IL10
16pneumonia30.4CD79A, IL1B, IL6, IL8, IL10, ICAM1
17plasmodium falciparum malaria30.4HP, IL10, ICAM1
18malaria30.3ALB, HP, IL10, ICAM1, FCER2, TNF
19diabetic nephropathy30.3ALB, HP, SOD2
20acute poststreptococcal glomerulonephritis30.3CD79A
21sinusitis30.3CD79A, IGHE
22mastitis30.3ALB, HP, IL1B, IL8
23methemoglobinemia30.3HP
24bronchiolitis30.2IL8, FCER2, IGHE
25paroxysmal nocturnal hemoglobinuria30.2CD14, HP
26pulmonary eosinophilia30.2IL8, SFTPD, IGHE
27eosinophilia30.1CD79A, CD14, IL8, IL10, FCER2, MPO
28cholangitis30.1ALB
29atherosclerosis29.9CD14, ALB, HP, IL1B, IL6, IL8
30adult respiratory distress syndrome29.9IL8, TNF
31eye disease29.9IL1B, IL6, SOD2
32tuberculosis29.9CD79A, ALB, HP, IL1B, IL10, TNF
33liver cirrhosis29.9CD14, ALB, HP
34glomerulonephritis29.8CD79A, ALB, IL1B, ICAM1, MPO
35ischemia29.7CD14, HP, ICAM1, CXCL2, SOD1, SOD2
36rheumatoid arthritis29.7CD79A, CD14, HP, IL1B, IL6, IL8
37connective tissue disease29.6CD79A, ALB, IL6, IL10, ICAM1, MPO
38ulcerative colitis29.6CD79A, CD14, IL1B, IL6, IL8, IL10
39diabetes mellitus29.4CD79A, CD14, ALB, HP, IL1B, IL6
40familial hypersensitivity pneumonitis10.5
41bird fancier's lung10.5
42farmer's lung10.5
43hantavirus pulmonary syndrome10.4
44sick building syndrome10.3
45mushroom workers' lung10.3
46malt worker's lung10.3
47celiac disease10.3
48asbestosis10.3
49bagassosis10.3
50ventilation pneumonitis10.3

Graphical network of the top 20 diseases related to Extrinsic Allergic Alveolitis:



Diseases related to extrinsic allergic alveolitis

Symptoms for Extrinsic Allergic Alveolitis

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Drugs & Therapeutics for Extrinsic Allergic Alveolitis

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Extrinsic Allergic Alveolitis

Search NIH Clinical Center for Extrinsic Allergic Alveolitis

Genetic Tests for Extrinsic Allergic Alveolitis

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Anatomical Context for Extrinsic Allergic Alveolitis

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33MalaCards
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MalaCards organs/tissues related to Extrinsic Allergic Alveolitis:

33
Lung, Testes, Monocytes, Skin, Myeloid, Nk cells, T cells

Animal Models for Extrinsic Allergic Alveolitis or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Extrinsic Allergic Alveolitis:

37 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.1CD14, IL1B, IL6, IL10, SOD1, TNF
2MP:00053818.0TNF, FCER2, ICAM1, IL10, IL6, ALB
3MP:00053918.0TNF, SOD2, SOD1, ICAM1, IL10, IL6
4MP:00053707.7TNF, SOD2, SOD1, IL10, IL6, HP
5MP:00020067.6TNF, SOD2, ICAM1, IL10, IL6, IL1B
6MP:00053797.5TNF, SOD1, ICAM1, IL10, IL6, ALB
7MP:00053697.4TNF, MPO, SOD2, SOD1, ICAM1, IL10
8MP:00036317.4TNF, SOD2, SOD1, ICAM1, IL10, IL6
9MP:00053857.3TNF, MPO, SOD2, SOD1, ICAM1, IL10
10MP:00053847.0TNF, FCER2, SOD2, SOD1, ICAM1, IL10
11MP:00107686.3SFTPD, TNF, MPO, FCER2, SOD2, SOD1
12MP:00053975.7CD79A, IGHE, SFTPD, TNF, MPO, FCER2
13MP:00053875.7SOD2, FCER2, MPO, TNF, SFTPD, IGHE
14MP:00053765.5SOD2, FCER2, MPO, TNF, SFTPD, IGHE

Publications for Extrinsic Allergic Alveolitis

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52PubMed
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Articles related to Extrinsic Allergic Alveolitis:

(show top 50)    (show all 155)
idTitleAuthorsYear
1
New occupational and environmental causes of asthma and extrinsic allergic alveolitis. (23153603)
2012
2
Acute life-threatening extrinsic allergic alveolitis in a paint controller. (21824996)
2011
3
Significance of specific IgG against sensitizing antigens in extrinsic allergic alveolitis: serological methods in EAA. (21924863)
2011
4
Extrinsic allergic alveolitis: incidence and mortality in the general population. (17307752)
2007
5
Extrinsic allergic alveolitis with eosinophil infiltration induced by 1,1,1,2-tetrafluoroethane (HFC-134a): a case report. (17827848)
2007
6
An unusual case of an acquired acral partial lipodystrophy (Barraquer-Simons syndrome) in a patient with extrinsic allergic alveolitis. (16716174)
2006
7
Production of soluble tumor necrosis factor receptors and tumor necrosis factor-alpha by alveolar macrophages in sarcoidosis and extrinsic allergic alveolitis. (15653992)
2005
8
Blood myeloid and lymphoid dendritic cells reflect Th1/Th2 balance in sarcoidosis and extrinsic allergic alveolitis. (15314973)
2003
9
Extrinsic allergic alveolitis induced by the yeast Debaryomyces hansenii. (12449192)
2002
10
Biochemical characteristics of fluid and cells of bronchoalveolar washings in patients with extrinsic allergic alveolitis]. (12474462)
2002
11
IgG antibodies typical for extrinsic allergic alveolitis--an inter-laboratory quality assessment. (11726311)
2001
12
Respiratory syndrome very similar to extrinsic allergic alveolitis due to Penicillium verrucosum in workers in a cheese factory. (11307594)
2001
13
Pet-fish food lung- a new form of extrinsic allergic alveolitis. (10756166)
2000
14
Histologically proven extrinsic allergic alveolitis with severe obstructive pulmonary emphysema (10756171)
2000
15
Effects of erythromycin on experimental extrinsic allergic alveolitis. (10051731)
1999
16
Elevated levels of soluble TNF receptors in bronchoalveolar lavage fluid in extrinsic allergic alveolitis. (10469029)
1999
17
Aerobiological analysis in a salami factory: a possible case of extrinsic allergic alveolitis by Penicillium camembertii. (10421864)
1999
18
Paper mill workers and chronic extrinsic allergic alveolitis. (8623683)
1996
19
Extrinsic allergic alveolitis and asthma in a sawmill worker: case report and review of the literature. (8130843)
1994
20
Expression of the adhesion molecule ICAM-1 on alveolar macrophages and in serum in extrinsic allergic alveolitis. (7903468)
1993
21
Extrinsic allergic alveolitis due to exposure to esparto dust. (1506815)
1992
22
Extrinsic allergic alveolitis: problems in diagnosis and a potential use for computed tomography. (1615180)
1992
23
Extrinsic allergic alveolitis secondary to carmine. (1678130)
1991
24
High-resolution computed tomography in extrinsic allergic alveolitis. (1999081)
1991
25
Mimics of sarcoidosis. Extrinsic allergic alveolitis. (1670003)
1991
26
Clinical guidelines and indications for bronchoalveolar lavage (BAL): extrinsic allergic alveolitis. (2292296)
1990
27
Limitations of hospital discharge diagnoses for surveillance of extrinsic allergic alveolitis. (2343875)
1990
28
Reversible pulmonary arterial hypertension in a 6-year-old girl with extrinsic allergic alveolitis. (2919518)
1989
29
Current concepts on bronchoalveolar lavage cells in extrinsic allergic alveolitis. (3068746)
1988
30
Extrinsic allergic alveolitis caused by a cold water humidifier. (3660296)
1987
31
Mast cells, atypical lymphocytes, and neutrophils in bronchoalveolar lavage in extrinsic allergic alveolitis. Comparison with other interstitial lung diseases. (2432812)
1987
32
Farmers' lung and extrinsic allergic alveolitis. (3684935)
1987
33
Antibody measurement in extrinsic allergic alveolitis. (6723835)
1984
34
Sporobolomyces: a possible cause of extrinsic allergic alveolitis. (6684133)
1983
35
Pulmonary arterial hypertension in extrinsic allergic alveolitis (EAA) (7091903)
1982
36
Bronchoalveolar lavage and transbronchial lung biopsy in sarcoidosis and extrinsic allergic alveolitis. (7173351)
1982
37
Extrinsic allergic alveolitis due to milk allergy: case report and review of the literature. (7065466)
1982
38
Phospholipids and microviscosity study in broncho-alveolar lavage fluids from control subjects and from patients with extrinsic allergic alveolitis. (7285366)
1981
39
Sawmill work and extrinsic allergic alveolitis. (6937828)
1980
40
Trapped air in extrinsic allergic alveolitis. (7444185)
1980
41
Clinical and immunological studies in pulmonary extrinsic allergic alveolitis. (Watson Prize Lecture, Royal College of Physicians and Surgeons, Glasgow, 4 April 1977). (152974)
1978
42
Editorial: Extrinsic allergic alveolitis. (1260333)
1976
43
Immunologically mediated lung diseases. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis. (944440)
1976
44
Extrinsic allergic alveolitis in Scottish maltworkers. (1252813)
1976
45
Extrinsic allergic alveolitis. (1089312)
1975
46
Extrinsic allergic alveolitis due to rat serum proteins. (1053443)
1975
47
Extrinsic allergic alveolitis owing to hypersensitivity to chickens-significance of sputum precipitins. (4209494)
1974
48
Extrinsic allergic alveolitis. (4574409)
1973
49
A bovine disease similar to farmer's lung: extrinsic allergic alveolitis. (4252199)
1971
50
Irreversible lung damage in extrinsic allergic alveolitis from pigeon dust inhalation. (5463319)
1970

Variations for Extrinsic Allergic Alveolitis

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Expression for genes affiliated with Extrinsic Allergic Alveolitis

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Extrinsic Allergic Alveolitis

Search GEO for disease gene expression data for Extrinsic Allergic Alveolitis.

Pathways for genes affiliated with Extrinsic Allergic Alveolitis

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Sources:
50PathCards, 38NCBI BioSystems Database, 54R&D Systems, 53QIAGEN, 60Thomson Reuters, 12EMD Millipore, 30KEGG, 55Reactome
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Pathways related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8SOD2, SOD1
29.7IL1B, IL6
3
Show member pathways
RANKL/RANK Signaling Pathway38
Apoptosis and survival APRIL and BAFF signaling60
9.6FCER2, ICAM1, IL10
49.4IGHE, FCER2, IL10
59.4IL8, IL6, IL1B
69.4IL1B, IL6, IL8
79.3SOD1, IL6, IL1B
89.3IL6, IL8, ICAM1
99.2MPO, IL8, IL6, CD14
109.1IL1B, IL6, TNF
11
Show member pathways
9.1CD14, IL6, IL8, ICAM1
12
Show member pathways
9.0IL6, IL8, SOD1, SOD2
138.9TNF, MPO, ICAM1, IL1B
14
Show member pathways
8.9CD79A, CD14, IL1B, FCER2, TNF
15
Show member pathways
8.8IL1B, IL6, IL10, TNF
16
Show member pathways
IL27-mediated signaling events38
8.8TNF, IL10, IL6, IL1B
178.7TNF, ICAM1, IL8, IL6
188.7TNF, FCER2, IL6, IL1B, CD14
198.5CD14, IL1B, IL6, IL10, TNF
208.5TNF, IL10, IL6, IL1B, CD14
21
Show member pathways
BCR signaling pathway38
TCR Signaling Pathway38
8.5TNF, IL10, IL6, IL1B, CD79A
22
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways60
Immune response IL 1 signaling pathway60
8.5TNF, IL8, IL6, IL1B, CD14
23
Show member pathways
Immune response MIF in innate immunity response60
8.5TNF, IL8, IL6, IL1B, CD14
248.5TNF, MPO, ICAM1, IL6, HP
25
Show member pathways
8.4TNF, IL10, IL8, IL6, IL1B
268.4TNF, IL10, IL8, IL6, IL1B
278.4TNF, IL10, IL8, IL6, IL1B
288.4TNF, ICAM1, IL10, IL6, IL1B
29
Show member pathways
8.4TNF, ICAM1, IL10, IL6, IL1B
308.4TNF, ICAM1, IL8, IL6, IL1B
31
Show member pathways
8.4TNF, ICAM1, IL8, IL6, IL1B
32
Show member pathways
8.3CXCL2, IL8, IL6, IL1B, CD14
33
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
8.3SFTPD, TNF, IL8, IL6, IL1B, CD14
34
Show member pathways
IL23-mediated signaling events38
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling38
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
8.3TNF, MPO, IL10, IL6, IL1B, CD14
358.2TNF, IL10, IL8, IL6, IL1B, CD14
36
Show member pathways
Toll-like receptor signaling pathway38
Regulation of toll-like receptor signaling pathway38
8.2TNF, IL10, IL8, IL6, IL1B, CD14
378.2TNF, IL10, IL8, IL6, IL1B, CD14
38
Show member pathways
8.1TNF, SOD2, SOD1, IL8, IL6, IL1B
398.1TNF, ICAM1, IL10, IL8, IL6, IL1B
408.0TNF, CXCL2, IL10, IL6, IL1B
41
Show member pathways
7.9TNF, CXCL2, IL8, IL6, IL1B
427.9IL1B, IL6, ICAM1, CXCL2, TNF
437.8TNF, CXCL2, ICAM1, IL8, IL1B, CD14
447.7TNF, CXCL2, IL8, IL6, IL1B, CD14
45
Show member pathways
7.6TNF, CXCL2, IL10, IL8, IL6, IL1B
46
Show member pathways
7.6TNF, CXCL2, IL10, IL8, IL6, IL1B
47
Show member pathways
7.6TNF, CXCL2, IL10, IL8, IL6, IL1B
487.6TNF, CXCL2, ICAM1, IL8, IL6, IL1B
49
Show member pathways
thioredoxin pathway38
7.2ALB, TNF, MPO, SOD2, SOD1, ICAM1
50
Show member pathways
6.9TNF, FCER2, SOD2, CXCL2, IL10, IL8

Compounds for genes affiliated with Extrinsic Allergic Alveolitis

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45Novoseek, 51PharmGKB, 11DrugBank, 29IUPHAR, 61Tocris Bioscience, 24HMDB, 3BitterDB
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Compounds related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show top 50)    (show all 303)
idCompoundScoreTop Affiliating Genes
1taurine chloramine458.8TNF, MPO, IL8, IL6, IL1B
2allergens458.8FCER2, SFTPD, IGHE, IL10, CD79A, CD14
3methacholine45 51 1110.7CD14, IL8, ICAM1, CD79A, MPO, IGHE
4mip 1alpha458.7IL10, TNF, IL8, IL6, IL1B
5okt3458.6CD79A, TNF, FCER2, ICAM1, IL6, IL10
6lipoteichoic acid458.5IL1B, CD14, IL6, IL8, IL10, TNF
75 aminosalicylic acid458.5IL8, IL10, MPO, TNF, IL1B
8sulfasalazine29 45 51 1111.5TNF, MPO, ICAM1, IL8, IL1B, HP
9triptolide458.5IL1B, ICAM1, IL8, TNF, CD14, IL6
10peptidoglycan45 299.4TNF, IL1B, CD14, IL6, IL8, IL10
11rantes458.4CXCL2, IL10, ICAM1, CD14, IL8, IL1B
12diphenyleneiodonium458.3SOD2, SOD1, ICAM1, IL8, IL1B, MPO
13gm-csf45 299.3IL6, IL1B, CD14, IL8, IL10, TNF
14polymyxin b458.2TNF, ICAM1, IL10, IL8, IL6, IL1B
15budesonide45 51 1110.2IL1B, IL8, IGHE, SFTPD, TNF, MPO
16il-12458.1TNF, IL10, IL8, IL1B, IL6
17fmlp458.1ICAM1, IL8, CD14, IL1B, FCER2, MPO
18herbimycin a45 619.0IL8, IL1B, ICAM1, FCER2, TNF, IL6
19pdtc457.9TNF, FCER2, SOD2, SOD1, ICAM1, IL8
20ascorbic acid45 248.9CD79A, HP, IGHE, ICAM1, ALB, SOD1
21ulinastatin457.9MPO, SOD1, ICAM1, IL10, IL8, IL6
22calcitriol45 61 24 1110.9CD14, IL10, SOD2, FCER2, TNF, ALB
23ivig457.9ALB, CD79A, IGHE, TNF, IL10, IL6
24hydrocortisone45 3 61 1110.9TNF, IGHE, FCER2, IL10, IL8, IL6
258-isoprostane457.9TNF, MPO, SOD1, ICAM1, IL10, IL8
26vitamin d457.8CD79A, CD14, ALB, HP, IL6, IL10
27pentoxifylline45 118.7TNF, MPO, ICAM1, IL10, IL8, IL6
28tarc457.7CXCL2, ICAM1, IL10, IL8, IGHE, TNF
29groalpha457.7TNF, CXCL2, ICAM1, IL10, IL8, IL6
30ccl345 298.6TNF, IL1B, IL6, IL10, IL8, CXCL2
31neopterin457.6TNF, FCER2, ICAM1, IL10, IL8, IL6
32creatinine457.5ALB, SOD2, MPO, SOD1, IL6, HP
33hyaluronic acid45 248.5CD79A, IL6, HP, ALB, IL1B, IL8
34methotrexate51 45 119.5IL6, SOD2, IL10, IL1B, ALB, CD79A
35prednisolone45 29 119.5IGHE, SFTPD, TNF, MPO, IL10, IL6
36sb 20358045 618.3IL1B, FCER2, CXCL2, ICAM1, IL10, TNF
37indomethacin45 29 61 1110.2IL1B, CD79A, ALB, IL6, SOD1, SOD2
38cyclosporin a45 29 619.2CD79A, IL10, IGHE, TNF, CD14, HP
39cycloheximide457.2CD14, IL6, IL8, ICAM1, SOD2, TNF
40fibrinogen457.1TNF, CXCL2, IL6, ALB, CD14, CD79A
41ly294002457.1TNF, SOD2, CD14, IL6, IL8, CXCL2
42endotoxin457.0ICAM1, IL10, IL8, IL6, IL1B, HP
43h2o2456.9CXCL2, SOD1, SOD2, MPO, TNF, IL8
44pge2456.4MPO, FCER2, CXCL2, ICAM1, IL10, IL8
45histamine45 29 248.3IGHE, SFTPD, TNF, MPO, FCER2, ICAM1
46n acetylcysteine456.3IL6, IL1B, CD79A, IL8, ICAM1, IGHE
47nitric oxide45 24 118.0HP, IL1B, ICAM1, CXCL2, SOD1, SOD2
48vegf455.8CD14, HP, IL1B, IL6, CD79A, ICAM1
49dexamethasone45 51 29 118.7SFTPD, IGHE, CD79A, TNF, FCER2, SOD2
50lactate455.1IGHE, SFTPD, TNF, MPO, FCER2, SOD2

GO Terms for genes affiliated with Extrinsic Allergic Alveolitis

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16Gene Ontology
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Cellular components related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1membrane raftGO:0451219.4CD79A, CD14, TNF
2external side of plasma membraneGO:0098978.5TNF, FCER2, ICAM1, IL6, CD79A
3extracellular vesicular exosomeGO:0700627.9MPO, FCER2, SOD1, ICAM1, HP, ALB
4extracellular regionGO:0055765.8IGHE, SFTPD, TNF, SOD1, CXCL2, IL8
5extracellular spaceGO:0056155.4CD14, SFTPD, TNF, MPO, SOD1, CXCL2

Biological processes related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

(show top 50)    (show all 52)
idNameGO IDScoreTop Affiliating Genes
1response to superoxideGO:00030310.2SOD2, SOD1
2hydrogen peroxide biosynthetic processGO:05066510.1SOD2, SOD1
3superoxide anion generationGO:04255410.0SOD2, SOD1
4positive regulation of humoral immune response mediated by circulating immunoglobulinGO:00292510.0TNF, FCER2
5defense response to bacteriumGO:04274210.0SFTPD, IL10, HP
6response to copper ionGO:04668810.0ICAM1, SOD1
7sequestering of triglycerideGO:03073010.0IL1B, TNF
8removal of superoxide radicalsGO:01943010.0SOD1, SOD2, MPO
9response to hydrogen peroxideGO:04254210.0HP, SOD1, SOD2
10positive regulation of calcidiol 1-monooxygenase activityGO:06055910.0IL1B, TNF
11positive regulation of heterotypic cell-cell adhesionGO:0341169.9TNF, IL1B
12positive regulation of fever generationGO:0316229.9TNF, IL1B
13response to electrical stimulusGO:0516029.9IL6, SOD2
14receptor biosynthetic processGO:0328009.9IL10, TNF
15negative regulation of cytokine secretion involved in immune responseGO:0027409.9TNF, IL10
16positive regulation of chemokine biosynthetic processGO:0450809.9TNF, IL1B
17superoxide metabolic processGO:0068019.9SOD1, SOD2
18regulation of I-kappaB kinase/NF-kappaB signalingGO:0431229.9IL1B, TNF
19regulation of mitochondrial membrane potentialGO:0518819.9SOD2, SOD1
20positive regulation of membrane protein ectodomain proteolysisGO:0510449.8IL1B, TNF
21negative regulation of lipid catabolic processGO:0509959.8TNF, IL1B
22response to ethanolGO:0454719.8CD14, ICAM1, SOD1
23response to heatGO:0094089.8SOD1, IL6, CD14
24epithelial cell proliferation involved in salivary gland morphogenesisGO:0606649.8TNF, IL6
25muscle cell cellular homeostasisGO:0467169.8SOD1, IL6
26negative regulation of lipid storageGO:0108889.8TNF, IL6
27positive regulation of cytokine secretionGO:0507159.7CD14, IL10, TNF
28response to lipopolysaccharideGO:0324969.7MPO, SOD2, IL6
29negative regulation of growth of symbiont in hostGO:0441309.7IL10, MPO, TNF
30embryonic digestive tract developmentGO:0485669.7TNF, IL8
31response to activityGO:0148239.7TNF, SOD2, IL10
32cellular response to lipopolysaccharideGO:0712229.6ICAM1, IL10, IL8, CD14
33positive regulation of chemokine productionGO:0327229.6IL6, TNF
34response to nutrient levelsGO:0316679.6SOD1, IL6
35negative regulation of fat cell differentiationGO:0455999.5TNF, SOD2, IL6
36response to mechanical stimulusGO:0096129.5TNF, MPO, IL6
37positive regulation of interleukin-6 productionGO:0327559.5IL1B, IL6, TNF
38activation of MAPK activityGO:0001879.5TNF, SOD1, IL1B
39response to glucocorticoidGO:0513849.4IL6, IL10, TNF
40response to molecule of bacterial originGO:0022379.4CXCL2, IL10, IL8
41positive regulation of cytokine productionGO:0018199.3TNF, SOD1
42positive regulation of NF-kappaB import into nucleusGO:0423469.3IL1B, TNF
43positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.2TNF, IL10, IL6, IL1B
44positive regulation of NF-kappaB transcription factor activityGO:0510929.2TNF, ICAM1, IL6, IL1B
45negative regulation of apoptotic processGO:0430668.9ALB, IL6, IL10, MPO
46negative regulation of cell proliferationGO:0082858.9IL1B, IL6, IL8, SOD2, TNF
47positive regulation of nitric oxide biosynthetic processGO:0454298.9IL1B, IL6, ICAM1, SOD2, TNF
48immune responseGO:0069558.8IL1B, IL8, CXCL2, IGHE
49response to drugGO:0424938.5TNF, SOD2, SOD1, ICAM1, IL10, IL6
50inflammatory responseGO:0069547.8TNF, CXCL2, IL10, IL8, IL6, IL1B

Molecular functions related to Extrinsic Allergic Alveolitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1antioxidant activityGO:0162099.7ALB, HP
2superoxide dismutase activityGO:0047849.7SOD2, SOD1
3cytokine activityGO:0051258.8IL1B, IL6, IL10, TNF
4protein bindingGO:0055155.9SFTPD, TNF, SOD1, CXCL2, ICAM1, IL8

Products for genes affiliated with Extrinsic Allergic Alveolitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Extrinsic Allergic Alveolitis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet