ROP
MCID: EXD001
MIFTS: 61

Exudative Vitreoretinopathy (ROP) malady

Genetic diseases, Rare diseases, Neuronal diseases, Eye diseases categories

Summaries for Exudative Vitreoretinopathy

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22Genetics Home Reference, 44NIH Rare Diseases, 66Wikipedia, 48OMIM, 34MalaCards
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NIH Rare Diseases:44 Familial exudative vitreoretinopathy (fevr) is a hereditary disorder that can cause progressive vision loss. this condition affects the retina, the light-sensitive tissue that lines the back of the eye, by preventing blood vessels from forming at the edges of the retina. this reduces the blood supply to retina. the signs and symptoms include vision loss or blindness, retinal detachment, strabismus, and a visible whiteness (leukocoria) in the normally black pupil. the severity of fevr varies widely, even within the same family. many people with this condition do not experience any vision problems.fevr has different inheritance patterns depending on the gene involved. most individuals have the autosomal dominant form of this condition, caused by mutations in the fzd4 or lrp5 gene. fevr caused by lrp5 gene mutations can also have an autosomal recessive inheritance. when this condition is caused by mutations in the ndp gene, it has an x-linked pattern of inheritance. last updated: 3/4/2011

MalaCards: Exudative Vitreoretinopathy, also known as familial exudative vitreoretinopathy, is related to norrie disease and retinal detachment. An important gene associated with Exudative Vitreoretinopathy is FZD4 (frizzled class receptor 4), and among its related pathways are MicroRNAs in cardiomyocyte hypertrophy and Wnt / Hedgehog / Notch. The compound calcium have been mentioned in the context of this disorder. Affiliated tissues include retina and eye, and related mouse phenotypes are hearing/vestibular/ear and vision/eye.

Genetics Home Reference:22 Familial exudative vitreoretinopathy is a hereditary disorder that can cause progressive vision loss. This condition affects the retina, the specialized light-sensitive tissue that lines the back of the eye. The disorder prevents blood vessels from forming at the edges of the retina, which reduces the blood supply to this tissue.

Wikipedia:66 Familial exudative vitreoretinopathy (FEVR) (pronounced \"fever\") is a genetic eye disorder affecting... more...

Description from OMIM:48 133780,613310,601813,305390,605750

Aliases & Classifications for Exudative Vitreoretinopathy

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9Disease Ontology, 10diseasecard, 48OMIM, 11DISEASES, 44NIH Rare Diseases, 22Genetics Home Reference, 50Orphanet, 21GeneTests, 23GTR, 63UMLS, 37MESH via Orphanet, 27ICD10 via Orphanet, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Neuronal diseases, Eye diseases


Characteristics (Orphanet epidemiological data):

50
familial exudative vitreoretinopathy:
Inheritance: Autosomal dominant,Autosomal recessive,X-linked recessive; Age of onset: Neonatal/infancy; Age of death: Any age
retinopathy of prematurity:
Prevalence: 1-5/10000; Age of onset: Neonatal/infancy; Age of death: Normal


Aliases & Descriptions:

exudative vitreoretinopathy 9 10 48 11
familial exudative vitreoretinopathy 9 44 22 50
exudative vitreoretinopathy, familial 44 21 23
fevr 44 22 50
criswick-schepens syndrome 44 50
exudative vitreoretinopathy 1 63
retinopathy of prematurity 50
retrolental fibroplasia 50
rop 50


External Ids:

Disease Ontology9 DOID:0050535
MESH via Orphanet37 C536382, D012178
ICD10 via Orphanet27 H35.0, H35.1
SNOMED-CT via Orphanet60 232063007, 415297005
UMLS via Orphanet64 C0339539, C1851402, C0035344

Related Diseases for Exudative Vitreoretinopathy

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18GeneCards, 19GeneDecks
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Diseases in the Exudative Vitreoretinopathy family:

Exudative Vitreoretinopathy 5 Exudative Vitreoretinopathy-3
Exudative Vitreoretinopathy 4

Diseases related to Exudative Vitreoretinopathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 69)
idRelated DiseaseScoreTop Affiliating Genes
1norrie disease31.2LRP5, NDP
2retinal detachment30.9NDP, IKBKG, FZD4
3familial exudative vitreoretinopathy, autosomal dominant30.8FZD4, LRP5
4retinopathy of prematurity30.6NDP, TSPAN12, IKBKG, FZD4
5osteoporosis-pseudoglioma syndrome30.4LRP5
6coats disease30.3IKBKG, NDP, TSPAN12
7endotheliitis10.8
8retinitis10.8
9x-linked familial exudative vitreoretinopathy10.7
10blindness10.6
11exudative vitreoretinopathy 510.5
12exudative vitreoretinopathy 410.5
13refractive error10.5
14skin hemangioma10.5
15lrp5-related familial exudative vitreoretinopathy, autosomal recessive10.4
16exudative vitreoretinopathy, x-linked10.4
17choroiditis10.4
18retinoblastoma10.4
19bronchopulmonary dysplasia10.3
20ndp-related retinopathy of prematurity10.3
21digeorge syndrome10.3
22glaucoma10.3
23myopia10.3
24osteoporosis10.3
25fzd4-related familial exudative vitreoretinopathy, autosomal dominant10.3
26lrp5-related familial exudative vitreoretinopathy, autosomal dominant10.3
27tspan12-related familial exudative vitreoretinopathy, autosomal dominant10.3
28bilateral retinoblastoma10.2
29cystoid macular edema10.2
30hyperglycemia10.2
31retinal disease10.2
32strabismus10.2
33twin twin transfusion syndrome10.2
34hypoxia10.2
35bacteremia10.2
36cystic fibrosis10.2
37primary open angle glaucoma10.2
38macular holes10.2
39anisometropia10.2
40astigmatism10.2
41cataract10.2
42open-angle glaucoma10.2
43persistent hyperplastic primary vitreous10.2
44exudative vitreoretinopathy-310.2
45hypertrophic scars10.1
46protein s deficiency10.1
47neuronitis10.1
48paralytic ileus10.1
49cortical blindness10.1
50tetralogy of fallot10.1

Graphical network of the top 20 diseases related to Exudative Vitreoretinopathy:



Diseases related to exudative vitreoretinopathy

Symptoms for Exudative Vitreoretinopathy

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48OMIM
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Symptoms by clinical synopsis from OMIM:

133780

Clinical features from OMIM:

133780,613310,601813,305390,605750

Drugs & Therapeutics for Exudative Vitreoretinopathy

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Exudative Vitreoretinopathy

Drug clinical trials:

Search ClinicalTrials for Exudative Vitreoretinopathy

Search NIH Clinical Center for Exudative Vitreoretinopathy

Search CenterWatch for Exudative Vitreoretinopathy

Genetic Tests for Exudative Vitreoretinopathy

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21GeneTests, 23GTR
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Genetic tests related to Exudative Vitreoretinopathy:

id Genetic test Affiliating Genes
1 Familial Exudative Vitreoretinopathy21 23 NDP

Anatomical Context for Exudative Vitreoretinopathy

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34MalaCards
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MalaCards organs/tissues related to Exudative Vitreoretinopathy:

34
Retina, Eye

Animal Models for Exudative Vitreoretinopathy or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Exudative Vitreoretinopathy:

38 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.3TSPAN12, FZD4, FZD6, FZD1, NDP
2MP:00053918.9LRP5, TSPAN12, FZD5, FZD4, FZD6, NDP
3MP:00053798.7IKBKG, FZD1, FZD4, FZD5, LRP5
4MP:00011868.7NDP, LRP5, FZD7, FZD4, FZD1, IKBKG
5MP:00053868.6NDP, IKBKG, FZD9, FZD4, FZD5, LRP5
6MP:00028738.5LRP5, FZD8, FZD4, FZD6, FZD1, IKBKG
7MP:00053818.5FZD7, FZD5, FZD4, FZD1, IKBKG
8MP:00053808.4LRP5, FZD7, FZD5, FZD4, FZD6, FZD1
9MP:00107718.3FZD7, FZD4, FZD6, FZD1, IKBKG
10MP:00053857.9LRP5, TSPAN12, FZD7, FZD5, FZD4, FZD1
11MP:00036317.9LRP5, FZD7, FZD5, FZD4, FZD6, FZD9
12MP:00107687.4LRP5, FZD8, FZD7, FZD5, FZD4, FZD6

Publications for Exudative Vitreoretinopathy

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53PubMed
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Articles related to Exudative Vitreoretinopathy:

(show top 50)    (show all 130)
idTitleAuthorsYear
1
Vitreomacular interface in patients with familial exudative vitreoretinopathy. (23334617)
2013
2
Asymmetric presentations of familial exudative vitreoretinopathy. (24082676)
2013
3
Familial Exudative Vitreoretinopathy caused by a Homozygous Mutation in TSPAN12 in a Cystic Fibrosis Infant. (23834558)
2013
4
Familial exudative vitreoretinopathy presenting with unilateral rhegmatogenous retinal detachment in a Malay teenager. (23645703)
2013
5
Familial exudative vitreoretinopathy in a premature child. (24144178)
2013
6
Screening for NDP mutations in 44 unrelated patients with familial exudative vitreoretinopathy or Norrie disease. (22563645)
2012
7
Recessive mutations in TSPAN12 cause retinal dysplasia and severe familial exudative vitreoretinopathy (FEVR). (22427576)
2012
8
Clinical characteristics and surgical management of familial exudative vitreoretinopathy-associated rhegmatogenous retinal detachment. (22277905)
2012
9
A mutation in the Norrie disease gene (NDP) associated with familial exudative vitreoretinopathy. (21960066)
2011
10
Novel TSPAN12 mutations in patients with familial exudative vitreoretinopathy and their associated phenotypes. (21552475)
2011
11
An essential role of the cysteine-rich domain of FZD4 in Norrin/Wnt signaling and familial exudative vitreoretinopathy. (21177847)
2011
12
Clinical presentation of familial exudative vitreoretinopathy. (21868098)
2011
13
Next-generation sequencing of a 40 Mb linkage interval reveals TSPAN12 mutations in patients with familial exudative vitreoretinopathy. (20159111)
2010
14
Novel and recurrent NDP gene mutations in familial cases of Norrie disease and X-linked exudative vitreoretinopathy. (20491809)
2010
15
Treatment of vascularly active familial exudative vitreoretinopathy with pegaptanib sodium (Macugen). (18317351)
2008
16
Rapid regression of retinal hemorrhage and neovascularization in a case of familial exudative vitreoretinopathy treated with intravitreal bevacizumab. (18795314)
2008
17
Novel human pathological mutations. Gene symbol: FZD4. Disease: exudative vitreoretinopathy. (18350654)
2007
18
Familial exudative vitreoretinopathy and macular hole exhibited in same individual. (17564927)
2007
19
Severe form of familial exudative vitreoretinopathy caused by homozygous R417Q mutation in frizzled-4 gene. (18161623)
2007
20
Novel human pathological mutations. Gene symbol: FZD4. Disease: familial exudative vitreoretinopathy. (17879448)
2007
21
Familial exudative vitreoretinopathy and osteoporosis-pseudoglioma syndrome caused by a mutation in the LRP5 gene. (17353424)
2007
22
Complexity of the genotype-phenotype correlation in familial exudative vitreoretinopathy with mutations in the LRP5 and/or FZD4 genes. (15981244)
2005
23
Genetic variants of frizzled-4 gene in familial exudative vitreoretinopathy and advanced retinopathy of prematurity. (15733276)
2005
24
Further evidence of genetic heterogeneity in familial exudative vitreoretinopathy; exclusion of EVR1, EVR3, and EVR4 in a large autosomal dominant pedigree. (15665352)
2005
25
Progression of familial exudative vitreoretinopathy after laser treatment. (15534139)
2004
26
Novel mutation in FZD4 gene in a Japanese pedigree with familial exudative vitreoretinopathy. (15488808)
2004
27
Spectrum and frequency of FZD4 mutations in familial exudative vitreoretinopathy. (15223780)
2004
28
Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q. (15024691)
2004
29
Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy. (12172548)
2002
30
A new locus for autosomal dominant familial exudative vitreoretinopathy maps to chromosome 11p12-13. (11179025)
2001
31
Familial exudative vitreoretinopathy associated with monocular axial myopia. (10380037)
1999
32
Vitrectomy for rhegmatogenous or tractional retinal detachment with familial exudative vitreoretinopathy. (10366074)
1999
33
Familial exudative vitreoretinopathy. Results of surgical management. (9627651)
1998
34
Identification of a recurrent missense mutation in the Norrie disease gene associated with a simplex case of exudative vitreoretinopathy. (9618247)
1998
35
Evidence for genetic heterogeneity in X-linked familial exudative vitreoretinopathy. (9299244)
1997
36
Familial exudative vitreoretinopathy associated with nonneovascular chronic angle-closure glaucoma. (9075081)
1997
37
X-linked familial exudative vitreoretinopathy. Report of one family. (7624602)
1995
38
Familial Exudative Vitreoretinopathy, Autosomal Dominant (20301326)
1993
39
X-linked familial exudative vitreoretinopathy (FEVR): results of DNA analysis with candidate genes. (8418643)
1993
40
X-linked recessive familial exudative vitreoretinopathy. (1642288)
1992
41
Signs, complications, and platelet aggregation in familial exudative vitreoretinopathy. (1985487)
1991
42
Optic disc neovascularization in dominant exudative vitreoretinopathy. (2483463)
1989
43
Criswick-Schepens syndrome (familial exudative vitreoretinopathy). Study of a Colombian kindred. (6487118)
1984
44
Similarity of familial exudative vitreoretinopathy and retinopathy of prematurity. (6687800)
1983
45
Falciform retinal fold as sign of familial exudative vitreoretinopathy. (6855020)
1983
46
Retinal involvement in familial exudative vitreoretinopathy. (7133626)
1982
47
Familial exudative vitreoretinopathy. (7342402)
1981
48
Congenital retinal fold as a sign of dominant exudative vitreoretinopathy. (6911005)
1981
49
Familial exudative vitreoretinopathy. (434067)
1979
50
Familial exudative vitreoretinopathy. (5394449)
1969

Variations for Exudative Vitreoretinopathy

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65UniProtKB/Swiss-Prot, 1 National Center for Biotechnology Information (Clinvar), 8dbSNP
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UniProtKB/Swiss-Prot genetic disease variations for Exudative Vitreoretinopathy:

65 (show all 20)
id Symbol AA change Variation ID SNP ID
1FZD4p.Met105ValVAR_038947
2FZD4p.Met157ValVAR_038948
3FZD4p.Pro33SerVAR_063920rs61735304
4FZD4p.Gly36AspVAR_063921
5FZD4p.Glu40GlnVAR_063922
6FZD4p.His69TyrVAR_063923rs80358282
7FZD4p.Met105ThrVAR_063924
8FZD4p.Ile114ThrVAR_063925
9FZD4p.Cys181ArgVAR_063927
10FZD4p.Cys204ArgVAR_063929
11FZD4p.Cys204TyrVAR_063930
12FZD4p.Met223LysVAR_063931
13FZD4p.Ile256ValVAR_063932
14FZD4p.Trp335CysVAR_063933
15FZD4p.Met342ValVAR_063934
16FZD4p.Arg417GlnVAR_063936
17FZD4p.Thr445ProVAR_063937
18FZD4p.Gly488AspVAR_063938
19FZD4p.Ser497PheVAR_063939
20FZD4p.Gly525ArgVAR_063940

Clinvar genetic disease variations for Exudative Vitreoretinopathy:

1
id Gene Name Type Significance SNP ID Assembly Location
1FZD4NM_012193.3(FZD4): c.1479_1484delGTGGAT (p.Met493_Trp494del)deletionPathogenicrs80358301GRCh37Chr 11, 86662314: 86662319
2FZD4NM_012193.3(FZD4): c.1501_1502delCT (p.Leu501Serfs)deletionPathogenicrs80358303GRCh37Chr 11, 86662296: 86662297
3FZD4NM_012193.3(FZD4): c.1250G> A (p.Arg417Gln)single nucleotide variantPathogenicrs80358294GRCh37Chr 11, 86662548: 86662548
4FZD4NM_012193.3(FZD4): c.1024A> G (p.Met342Val)single nucleotide variantPathogenicrs80358293GRCh37Chr 11, 86662774: 86662774
5FZD4NM_012193.3(FZD4): c.1005G> C (p.Trp335Cys)single nucleotide variantPathogenicrs80358292GRCh37Chr 11, 86662793: 86662793

Expression for genes affiliated with Exudative Vitreoretinopathy

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Exudative Vitreoretinopathy

Search GEO for disease gene expression data for Exudative Vitreoretinopathy.

Pathways for genes affiliated with Exudative Vitreoretinopathy

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51PathCards, 39NCBI BioSystems Database, 5Cell Signaling Technology, 58SinoBiological, 56Reactome, 54QIAGEN, 31KEGG, 61Thomson Reuters, 52PharmGKB, 55R&D Systems
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Pathways related to Exudative Vitreoretinopathy according to GeneCards/GeneDecks:

(show all 26)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5IKBKG, FZD1, LRP5
29.4FZD6, FZD5, LRP5
3
Show member pathways
9.2FZD5, FZD4, FZD9, FZD1
4
Show member pathways
8.0FZD4, FZD6, FZD1, FZD8, FZD5, FZD7
5
Show member pathways
7.7FZD8, FZD4, FZD5, FZD6, FZD9, FZD1
67.7FZD8, FZD7, FZD5, FZD4, FZD6, FZD1
7
Show member pathways
7.7FZD9, FZD7, FZD5, FZD4, FZD6, FZD8
8
Show member pathways
7.7FZD7, FZD1, FZD9, FZD4, FZD6, FZD8
97.7FZD1, FZD9, FZD8, FZD7, FZD5, FZD4
107.7FZD8, FZD7, FZD5, FZD4, FZD9, FZD1
117.7FZD1, FZD9, FZD7, FZD6, FZD4, FZD5
12
Show member pathways
Translation Non genomic rapid action of Androgen Receptor61
7.7FZD1, FZD7, FZD9, FZD6, FZD5, FZD4
13
Show member pathways
7.7FZD9, FZD1, FZD6, FZD4, FZD5, FZD7
14
Show member pathways
7.7FZD9, FZD7, FZD1, FZD5, FZD6, FZD4
15
Show member pathways
7.7FZD1, FZD9, FZD6, FZD4, FZD7, FZD8
16
Show member pathways
Proteasome Degradation39
Immune response Antigen presentation by MHC class I61
7.6FZD8, FZD7, FZD5, FZD4, FZD6, FZD1
17
Show member pathways
DNA damage response (only ATM dependent)39
Wnt Signaling Pathway and Pluripotency39
7.4FZD5, LRP5, FZD8, FZD1, FZD7, FZD6
18
Show member pathways
Wnt Signaling Pathway NetPath39
7.4FZD4, FZD1, FZD9, FZD6, FZD7, FZD8
197.4LRP5, FZD1, FZD9, FZD6, FZD4, FZD5
20
Show member pathways
7.4FZD7, FZD5, FZD6, FZD9, FZD4, FZD1
217.4LRP5, FZD1, FZD9, FZD6, FZD4, FZD5
227.4FZD4, LRP5, FZD7, FZD1, FZD9, FZD8
237.4LRP5, FZD8, FZD7, FZD5, FZD4, FZD6
247.3FZD6, IKBKG, FZD7, FZD8, FZD5, FZD4
257.3FZD8, FZD7, FZD5, FZD4, FZD6, FZD9
267.3FZD9, FZD5, FZD1, IKBKG, FZD6, FZD4

Compounds for genes affiliated with Exudative Vitreoretinopathy

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46Novoseek, 52PharmGKB, 25HMDB, 12DrugBank
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Compounds related to Exudative Vitreoretinopathy according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcium46 52 25 1210.1IKBKG, FZD1, FZD9, FZD6, FZD4, FZD5

GO Terms for genes affiliated with Exudative Vitreoretinopathy

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17Gene Ontology
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Cellular components related to Exudative Vitreoretinopathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1clathrin-coated endocytic vesicle membraneGO:0306699.5FZD5, FZD4
2neuron projection membraneGO:0325899.4FZD1, FZD6, FZD7
3cell projectionGO:0429959.3FZD4, FZD5, FZD8
4apical part of cellGO:0451779.2FZD7, FZD6, FZD1
5cell surfaceGO:0099869.1FZD5, FZD4, FZD9, FZD1, NDP
6integral component of membraneGO:0160217.7FZD1, FZD9, FZD5, FZD7, FZD8, TSPAN12
7cytoplasmGO:0057377.2FZD8, FZD7, FZD5, FZD4, FZD6, FZD9
8plasma membraneGO:0058866.7GORASP2, LRP5, FZD8, FZD7, FZD5, FZD4

Biological processes related to Exudative Vitreoretinopathy according to GeneCards/GeneDecks:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1retinal blood vessel morphogenesisGO:06130410.2LRP5, FZD4
2retina vasculature morphogenesis in camera-type eyeGO:06129910.2FZD4, NDP
3extracellular matrix-cell signalingGO:03542610.1FZD4, LRP5, NDP
4Wnt signaling pathway involved in dorsal/ventral axis specificationGO:04433210.0FZD5, LRP5
5Wnt signaling pathwayGO:0160559.8NDP, LRP5, FZD4
6negative regulation of cell-substrate adhesionGO:0108129.7FZD4, FZD7
7positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.7NDP, FZD1, LRP5, FZD4
8cellular response to retinoic acidGO:0713009.6FZD4, FZD7
9Wnt signaling pathway, calcium modulating pathwayGO:0072239.6FZD1, FZD4, FZD7
10substrate adhesion-dependent cell spreadingGO:0344469.5FZD7, FZD4
11positive regulation of JUN kinase activityGO:0435079.5FZD8, FZD5, FZD4
12G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerGO:0071999.5FZD7, FZD1, FZD6
13angiogenesisGO:0015259.4FZD6, TSPAN12, FZD5
14embryo developmentGO:0097909.4FZD1, FZD9, FZD4, FZD8
15T cell differentiation in thymusGO:0330779.1FZD5, FZD7, FZD8
16vasculature developmentGO:0019449.0FZD7, FZD8, FZD1, FZD9
17positive regulation of transcription, DNA-templatedGO:0458939.0LRP5, FZD7, FZD4, FZD1, NDP
18neuron differentiationGO:0301828.7FZD7, FZD1, FZD4, FZD8, FZD5
19positive regulation of transcription from RNA polymerase II promoterGO:0459448.6FZD5, LRP5, FZD8, IKBKG
20axonogenesisGO:0074098.5FZD8, FZD5, FZD1, FZD6, FZD7
21brain developmentGO:0074208.4FZD7, FZD5, FZD1, FZD9, FZD8, FZD4
22gonad developmentGO:0084068.3FZD8, FZD1, FZD9, FZD6, FZD5, FZD7
23canonical Wnt signaling pathwayGO:0600707.9NDP, LRP5, FZD8, FZD7, FZD4, FZD9

Molecular functions related to Exudative Vitreoretinopathy according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1protein homodimerization activityGO:0428039.3NDP, IKBKG, FZD9, FZD4
2frizzled bindingGO:0051099.0FZD7, FZD1, NDP
3ubiquitin protein ligase bindingGO:0316258.9FZD8, FZD5, FZD4, FZD6
4PDZ domain bindingGO:0301657.8FZD8, FZD7, FZD5, FZD4, FZD6, FZD9
5G-protein coupled receptor activityGO:0049307.7FZD8, FZD7, FZD5, FZD4, FZD6, FZD9
6Wnt-protein bindingGO:0171477.6LRP5, FZD8, FZD7, FZD5, FZD4, FZD6
7Wnt-activated receptor activityGO:0428137.3FZD1, LRP5, FZD9, FZD6, FZD4, FZD5
8protein bindingGO:0055155.9GORASP2, LRP5, FZD8, FZD7, FZD5, FZD4

Products for genes affiliated with Exudative Vitreoretinopathy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Exudative Vitreoretinopathy

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet