MCID: EXD008
MIFTS: 51

Exudative Vitreoretinopathy 1 malady

Categories: Genetic diseases, Rare diseases, Eye diseases, Neuronal diseases

Aliases & Classifications for Exudative Vitreoretinopathy 1

About this section
Sources:
49OMIM, 10Disease Ontology, 21GeneReviews, 45NIH Rare Diseases, 22GeneTests, 12DISEASES, 51Orphanet, 67UniProtKB/Swiss-Prot, 36MeSH, 24GTR, 65UMLS, 27ICD10, 29ICD9CM, 42NCIt, 59SNOMED-CT, 66UMLS via Orphanet, 28ICD10 via Orphanet, 37MESH via Orphanet, 34MedGen, 61The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Exudative Vitreoretinopathy 1:

Name: Exudative Vitreoretinopathy 1 49 65
Retinopathy of Prematurity 49 10 45 22 12 51 36 24 65
Retrolental Fibroplasia 10 45 51
Familial Exudative Vitreoretinopathy, Autosomal Dominant 21 22
Autosomal Dominant Familial Exudative Vitreoretinopathy 67 24
Vitreoretinopathy, Exudative 1 67 24
 
Adfevr 21 22
Rop 45 51
Criswick-Schepens Syndrome 67
Premature Retinopathy 10
Fevr 67
Evr1 67

Characteristics:

Orphanet epidemiological data:

51
retinopathy of prematurity:
Age of onset: Infancy,Neonatal; Age of death: normal life expectancy

HPO:

61
exudative vitreoretinopathy 1:
Onset and clinical course: slow progression, infantile onset
Inheritance: autosomal dominant inheritance


Classifications:

Orphanet: 51 
Rare eye diseases


External Ids:

OMIM49 133780
Disease Ontology10 DOID:13025
ICD9CM29 362.20, 362.21
MeSH36 D012178
NCIt42 C34982
Orphanet51 90050
UMLS via Orphanet66 C0035344
ICD10 via Orphanet28 H35.1
MESH via Orphanet37 D012178
UMLS65 C0035344, C1851402

Summaries for Exudative Vitreoretinopathy 1

About this section
OMIM:49 Familial exudative vitreoretinopathy (FEVR) is an inherited disorder characterized by the incomplete development of the... (133780) more...

MalaCards based summary: Exudative Vitreoretinopathy 1, also known as retinopathy of prematurity, is related to exudative vitreoretinopathy 2, x-linked and fzd4-related familial exudative vitreoretinopathy, autosomal dominant, and has symptoms including exudative vitreoretinopathy, vitreous hemorrhage and peripheral retinal avascularization. An important gene associated with Exudative Vitreoretinopathy 1 is FZD4 (Frizzled Class Receptor 4), and among its related pathways are Vemurafenib Pathway, Pharmacodynamics and Transcription_P53 signaling pathway. Affiliated tissues include eye, retina and lung, and related mouse phenotypes are embryo and normal.

UniProtKB/Swiss-Prot:67 Vitreoretinopathy, exudative 1: A disorder of the retinal vasculature characterized by an abrupt cessation of growth of peripheral capillaries, leading to an avascular peripheral retina. This may lead to compensatory retinal neovascularization, which is thought to be induced by hypoxia from the initial avascular insult. New vessels are prone to leakage and rupture causing exudates and bleeding, followed by scarring, retinal detachment and blindness. Clinical features can be highly variable, even within the same family. Patients with mild forms of the disease are asymptomatic, and their only disease related abnormality is an arc of avascular retina in the extreme temporal periphery. In many ways the disease resembles retinopathy of prematurity but there is no evidence of prematurity or small birth weight in the patient history.

GeneReviews summary for NBK1147

Related Diseases for Exudative Vitreoretinopathy 1

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Diseases in the Exudative Vitreoretinopathy family:

Exudative Vitreoretinopathy 5 Exudative Vitreoretinopathy 3
Exudative Vitreoretinopathy 6 Exudative Vitreoretinopathy 4
exudative vitreoretinopathy 1 Lrp5-Related Familial Exudative Vitreoretinopathy, Autosomal Recessive
Fzd4-Related Familial Exudative Vitreoretinopathy, Autosomal Dominant Lrp5-Related Familial Exudative Vitreoretinopathy, Autosomal Dominant
Tspan12-Related Familial Exudative Vitreoretinopathy, Autosomal Dominant

Diseases related to Exudative Vitreoretinopathy 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 61)
idRelated DiseaseScoreTop Affiliating Genes
1exudative vitreoretinopathy 2, x-linked31.1FZD4, LRP5, NDP
2fzd4-related familial exudative vitreoretinopathy, autosomal dominant12.7
3lrp5-related familial exudative vitreoretinopathy, autosomal dominant12.7
4tspan12-related familial exudative vitreoretinopathy, autosomal dominant12.7
5ndp-related retinopathy of prematurity12.5
6exudative vitreoretinopathy11.6
7rett syndrome10.6
8pulmonary fibrosis10.6
9bruxism10.6
10intestinal pseudo-obstruction10.6
11retina lymphoma10.5FZD4, NDP, TSPAN12
12hyperostosis, endosteal10.4FZD4, LRP5, NDP
13delusional disorder10.4FZD4, NDP, VEGFA
14endotheliitis10.4
15pancreatitis10.4
16lipodystrophy due to peptidic growth factors deficiency10.4ANGPT2, FLT1
17bladder urachal squamous cell carcinoma10.4FLT1, KDR, VEGFA
18hepatitis10.4
19posterior polar cataract10.4FZD4, LRP5, NDP, TSPAN12
20chronic venous leg ulcers10.4TEK, VEGFA
21immature cataract10.4FLT1, KDR, VEGFA
22right bundle branch block10.4ANGPT2, FLT1, VEGFA
23hemophilia a10.4
24hemophilia10.4
25syncope10.4
26hypospadias-hypertelorism-coloboma and deafness syndrome10.4FLT1, KDR, VEGFA
27leukemia10.3
28prostatitis10.3
29pyridoxal 5'-phosphate-dependent epilepsy10.3ANGPT2, TEK
30diabetes mellitus, insulin-dependent, 310.3ANGPT2, KDR, VEGFA
31malignant conjunctiva melanoma10.3FLT1, KDR, VEGFA
32seminal vesicle acute gonorrhea10.3FLT1, KDR, VEGFA
33lymphoma10.3
34adenocarcinoma10.3
35cerebritis10.3
36thyroiditis10.3
37middle cranial fossa meningioma10.3ANGPT2, TEK
38adult pulmonary langerhans cell histiocytosis10.3FLT1, KDR, VEGFA
39leptospirosis10.3IGF1, SERPINH1, VEGFA
40blind hypertensive eye10.3FZD4, LRP5, NDP, PER1
41common bile duct neoplasm10.3FLT1, VEGFA
42exudative vitreoretinopathy 510.3
43microcephaly with or without chorioretinopathy, lymphedema, or mental retardation10.3
44exudative vitreoretinopathy 310.3
45exudative vitreoretinopathy 410.3
46transient neonatal neutropenia10.3EPO, SERPINH1
47esophagitis10.3
48cervicitis10.3
49neuronitis10.3
50thymus gland disease10.3FZD4, LRP5, NDP, TSPAN12, VEGFA

Graphical network of the top 20 diseases related to Exudative Vitreoretinopathy 1:



Diseases related to exudative vitreoretinopathy 1

Symptoms for Exudative Vitreoretinopathy 1

About this section

Symptoms by clinical synopsis from OMIM:

133780

Clinical features from OMIM:

133780

HPO human phenotypes related to Exudative Vitreoretinopathy 1:

(show all 12)
id Description Frequency HPO Source Accession
1 exudative vitreoretinopathy HP:0030490
2 vitreous hemorrhage HP:0007902
3 peripheral retinal avascularization HP:0007685
4 reduced visual acuity HP:0007663
5 recurrent fractures HP:0002757
6 falciform retinal fold HP:0001493
7 posterior vitreous detachment HP:0001489
8 retinal exudate HP:0001147
9 pigmentary retinal degeneration HP:0001146
10 blindness HP:0000618
11 retinal detachment HP:0000541
12 subcapsular cataract HP:0000523

Drugs & Therapeutics for Exudative Vitreoretinopathy 1

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Drugs for Exudative Vitreoretinopathy 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 200)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Nitrous oxideapprovedPhase 4, Phase 315110024-97-2948
Synonyms:
00583_FLUKA
10024-97-2
126386-65-0
129451-49-6
130835-71-1
147527-07-9
175876-44-5
295590_ALDRICH
794457-85-5
847968-13-2
850203-00-8
AC1L1ADZ
C00887
CCRIS 1225
CHEBI:17045
CHEMBL1234579
CID948
D00102
D009609
Diazyne 1-oxide
Dinitrogen monoxide
Dinitrogen oxide
Distickstoffmonoxid
E942
EINECS 233-032-0
FEMA 2779
FEMA No. 2779
Factitious air
Gas, Laughing
Gas, laughing
Gaz hilarant
HSDB 504
Hyponitrous acid anhydride
LS-7622
Lachgas
Laughing gas
N2O
NITROUS-OXIDE
NNO
 
Nitral
Nitrogen hypoxide
Nitrogen monoxide
Nitrogen oxide (N2O)
Nitrogen protoxide
Nitrogenium oxydulatum
Nitrous Oxide
Nitrous oxide
Nitrous oxide (JP15/USP)
Nitrous oxide (TN)
Nitrous oxide [Anaesthetics, volatile]
Nitrous oxide [JAN]
Nitrous oxide [UN1070] [Nonflammable gas]
Nitrous oxide [UN1070] [Nonflammable gas]
Nitrous oxide [anaesthetics, volatile]
Nitrous oxide [jan]
Nitrous oxide, JAN, USAN
Nitrous oxide, compressed
Nitrous oxide, refrigerated liquid
Nitrous oxide, refrigerated liquid [UN2201] [Nonflammable gas]
Nitrous oxide, refrigerated liquid [UN2201] [Nonflammable gas]
Nitrous-oxide
Oxide, Nitrous
Oxide, nitrous
Oxido nitroso
Oxido nitroso [Spanish]
Oxidodinitrogen(N--N)
Oxyde nitreux
Protoxyde d'azote [French]
Stickdioxyd
Stickdioxyd [German]
Stickstoff(I)-oxid
UN1070
UN2201
gaz hilarant
nitrogenium oxydulatum
nitrous oxide
oxidodinitrogen(N--N)
oxyde nitreux
protoxyde d'azote
2
Propofolapproved, investigationalPhase 49312078-54-84943
Synonyms:
2, 6-Diisopropylphenol
2,6 Diisopropylphenol
2,6-Bis(1-methylethyl)phenol
2,6-Bis(Isopropyl)-phenol
2,6-DIISOPROPYLPHENOL
2,6-Diisopropyl phenol
2,6-Diisopropylphenol
2,6-bis(1-methylethyl)-phenol
2,6-di(propan-2-yl)phenol
2078-54-8
28449-97-0
4-06-00-03435 (Beilstein Handbook Reference)
50356-15-5
AB00513968
AC-2038
AC1L1J9Y
AC1Q1OUI
AI3-26295
AM-149
Abbott Brand of Propofol
Alpha Brand of Propofol
Ampofol
Aquafol
Astra Brand of Propofol
AstraZeneca Brand of Propofol
BIDD:GT0436
BPBio1_000950
BPBio1_000969
BRD-K82255054-001-03-5
BRN 1866484
BSPBio_000862
Biomol-NT_000248
Braun Brand of Propofol
C07523
C12H18O
CAS-2078-54-8
CCRIS 9000
CHEBI:44915
CHEMBL526
CID4943
CPD-11437
CPD000059151
Curamed Brand of Propofol
D00549
D015742
D0617
D126608
D126608_ALDRICH
DB00818
DDS-04F
Diisopropylphenol
Dipravan
Diprivan
Diprivan (TN)
Diprivan Injectable emulsion
Disoprivan
Disoprofol
EINECS 218-206-6
EU-0100437
Fresenius Brand of Propofol
Fresenius Kabi Brand of Propofol
Fresofol
HMS1570L04
HMS2089O21
HMS2094E17
 
HSDB 7123
ICI 35,868
ICI 35868
ICI-35,868
ICI-35868
ICI35,868
ICI35868
InChI=1/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H
Ivofol
Jsp004266
Juste Brand of Propofol
LS-996
Lopac-D126608
Lopac0_000437
MLS001066348
MLS001335999
MLS002454360
MolPort-001-794-517
NCGC00015389-01
NCGC00015389-02
NCGC00015389-04
NCGC00015389-09
NCGC00091538-01
NCGC00091538-02
NCGC00091538-03
NCGC00091538-04
NCGC00091538-05
NCGC00091538-06
NSC 5105
NSC5105
PFL
Parnell Brand of Propofol
Pisa Brand of Propofol
Prestwick0_000931
Prestwick1_000931
Prestwick2_000931
Prestwick3_000931
Propofol
Propofol (JAN/USAN/INN)
Propofol Abbott
Propofol Fresenius
Propofol IDD-D
Propofol MCT
Propofol Rovi
Propofol [USAN:INN:BAN]
Propofol(2,6-Diisopropylphenol)
Propofol-Lipuro
Propofolum
Propofolum [Latin]
Rapinovet
Recofol
Rovi Brand of Propofol
S01-0189
SAM002264610
SMR000059151
SPBio_003031
SPECTRUM1505022
ST50405911
Schering Brand of Propofol
UNII-YI7VU623SF
W505102_ALDRICH
ZD-0859
ZINC00968303
Zeneca Brand of Propofol
ghl.PD_Mitscher_leg0.558
nchembio.552-comp7
propofol
3
SevofluraneapprovedPhase 442928523-86-65206
Synonyms:
1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
28523-86-6
AC-15484
AC1L1JU0
BRN 2041023
Bax 3084
C009250
C07520
C4H3F7O
CHEBI:9130
CHEMBL1200694
CID5206
D00547
DB01236
F0691
Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether
Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
I14-13357
LS-67851
MR6S4
 
MR_6S4
MolPort-001-775-746
NCGC00167421-01
PC4681
Sevofluran
Sevoflurane
Sevoflurane (JAN/USAN/INN)
Sevoflurane [USAN:INN:BAN:JAN]
Sevoflurano
Sevoflurano [INN-Spanish]
Sevofluranum
Sevofluranum [INN-Latin]
Sevofrane
Sevorane
Sojourn
UNII-38LVP0K73A
Ultane
Ultane (TN)
ZINC01530810
fluoromethyl hexafluoroisopropyl ether
fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
sevoflurane
4
KetamineapprovedPhase 44676740-88-13821
Synonyms:
(+-)-Ketamine
(+/-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
(+/-)-2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
(+/-)-Ketamine
(-)-Ketamine
(S)-(-)-Ketamine
(S)-Ketamine
(±)-ketamine
100477-72-3
2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone
2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
2-(Methylamino)-2-(2-chlorophenyl)cyclohexanone
2-(methylamino)-2-(2-chlorophenyl)cyclohexanone
2-(o-Chlorophenyl)-2-(methylamino)-cyclohexanone
2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
2-(o-chlorophenyl)-2-(methylamino)-cyclohexanone
33643-45-7
6740-88-1
79499-51-7
AC1L1GSH
AC1Q40UR
AKOS001053247
BRN 2216965
C07525
C13H16ClNO
CHEBI:138833
CHEBI:6121
CHEMBL742
CI 581 base
CI-581
CID3821
CLSTA 20
Calypsol
Cetamina
Cetamina [INN-Spanish]
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)- (9CI)
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)- (9CI)
Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+/-)- (8CI)
D08098
DB01221
DEA No. 7285
DL-ketamine
 
DivK1c_000217
EINECS 229-804-1
Esketamine
Green
IDI1_000217
KBio1_000217
KETAMINE
KETAMINE HCL
Ketaject
Ketalar
Ketalar base
Ketamina
Ketamine (INN)
Ketamine Base
Ketamine HCL
Ketamine Hydrochloride
Ketamine [INN:BAN]
Ketamine hydrochloride
Ketaminum
Ketaminum [INN-Latin]
Ketanest
Ketoject
Ketolar
L-Ketamine
LS-57301
MLS001331674
MolPort-001-838-070
NCGC00159480-02
NCGC00159480-03
NINDS_000217
NMDA
NSC 70151
NSC70151
SMR000238141
Special K
Special K [street name]
Special k
T385
Tekam
Tekam (TN)
UNII-690G0D6V8H
dl-Ketamine
ketamine
l-Ketamine
5
RanibizumabapprovedPhase 4, Phase 3, Phase 2460347396-82-1459903
Synonyms:
347396-82-1
D05697
Lucentis
Lucentis (TN)
 
Ranibizumab
Ranibizumab (USAN/INN)
Ranibizumab (genetical recombination)
Ranibizumab (genetical recombination) (JAN)
ranibizumab
rhuFab V2
6
Indomethacinapproved, investigationalPhase 4, Phase 310653-86-13715
Synonyms:
1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
1z9h
37242-43-6
503560-73-4
53-86-1
74252-25-8 (hydrochloride salt, tri-hydrate)
7681-54-1 (hydrochloride salt)
91853-74-6
AB00052022
AC-532
AC1L1GJQ
AKOS000592893
Aconip
Aconip (TN)
Amuno
Apo-Indomethacin
Arthrexin
Artracin
Artrinovo
Artrivia
BIDD:GT0132
BIM-0050670.0001
BPBio1_000160
BRD-K57222227-001-06-1
BRN 0497341
BSPBio_000144
BSPBio_001149
BSPBio_002176
Bio-0704
Bio2_000405
Bio2_000885
Bonidin
Bonidon
Bonidon Gel
C01926
CAS-53-86-1
CCRIS 3502
CHEBI:49662
CHEMBL6
CID3715
CPD-10545
Catlep
Chibro-amuno
Chrono-indicid
Chrono-indocid
Confortid
D00141
DB00328
DESMETHYL INDOMETHACIN
DivK1c_000271
Dolcidium
Dolcidium PL
Dolovin
Durametacin
EINECS 200-186-5
EU-0100692
Elmetacin
Flexin continus
HMS1362I11
HMS1568H06
HMS1792I11
HMS1920F21
HMS1990I11
HMS2089N19
HMS2091N09
HMS500N13
HSDB 3101
Hicin
I 7378
I0655
I7378_SIGMA
I8280_SIGMA
IDI1_000271
IDI1_002160
IMN
IN1454
Idomethine
Imbrilon
Inacid
Indacin
Indameth
Indmethacine
Indo-Lemmon
Indo-Spray
Indo-phlogont
Indo-rectolmin
Indo-tablinen
Indocid
Indocid (pharmaceutical)
Indocid Pda
Indocid Sr
Indocin
Indocin (TN)
Indocin I.V
Indocin I.V.
Indocin Sr
Indolar SR
Indomecol
Indomed
Indomee
Indomet 140
Indometacin
Indometacin (JP15/INN)
Indometacina
Indometacina [INN-Spanish]
Indometacine
Indometacine [INN-French]
Indometacinum
Indometacinum [INN-Latin]
 
Indometacyna
Indometacyna [Polish]
Indomethacin
Indomethacin & MAP-30
Indomethacin (USP)
Indomethacin Er
Indomethacin [USAN:BAN]
Indomethacin, Indochron E-R, Indocin-SR, Indocid, Indocin, Indomethacin
Indomethacine
Indomethacinum
Indomethancin
Indomethazine
Indomethegan
Indomethine
Indometicina
Indometicina [Spanish]
Indomo
Indomod
Indoptic
Indoptol
Indorektal
Indoxen
Inflazon
Infrocin
Inteban sp
KBio1_000271
KBio2_000489
KBio2_001399
KBio2_003057
KBio2_003967
KBio2_005625
KBio2_006535
KBio3_000897
KBio3_000898
KBio3_001396
KBioGR_000395
KBioGR_000489
KBioSS_000489
KBioSS_001399
L000959
LS-187
LS-82147
Lausit
Liometacen
Lopac-I-7378
Lopac0_000692
MLS000069402
MLS000758212
MLS001074194
Metacen
Metartril
Methazine
Metindol
Mezolin
Miametan
Mikametan
Mobilan
MolMap_000032
MolPort-000-917-894
NCGC00015562-01
NCGC00015562-02
NCGC00015562-03
NCGC00015562-08
NCGC00015562-19
NCGC00024135-02
NCGC00024135-04
NCGC00024135-05
NCGC00024135-06
NCGC00024135-07
NCGC00024135-08
NCGC00024135-09
NCGC00024135-11
NCI-C56144
NCI60_041708
NINDS_000271
Novo-Methacin
Novomethacin
Oprea1_686105
Prestwick0_000272
Prestwick1_000272
Prestwick2_000272
Prestwick3_000272
Prestwick_597
Reumacide
Rhemacin LA
Rheumacin LA
S00108
S1723_Selleck
SMR000058195
SMR000449290
SPBio_000979
SPBio_002363
SPECTRUM1500350
Sadoreum
Spectrum2_000970
Spectrum3_000468
Spectrum4_000018
Spectrum5_000868
Spectrum_000919
Tannex
Tivorbex
Tocris-1708
UNII-XXE1CET956
UPCMLD-DP023
UPCMLD-DP023:001
USAN
Vonum
indometacin
indomethacin
nchembio.147-comp11
{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
7
IbuprofenapprovedPhase 4, Phase 3, Phase 245615687-27-13672
Synonyms:
(+-)-2-(P-Isobutylphenyl)propionic acid
(+-)-Ibuprofen
(+-)-P-Isobutylhydratropic acid
(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid
(4-Isobutylphenyl)-alpha-methylacetic acid
(RS)-ibuprofen
139466-08-3
15687-27-1
2-(4-Isobutylphenyl)propanoic acid
4-Isobutylhydratropic acid
58560-75-1
7 Select Childrens Ibuprofen
7 Select Ibuprofen
AC-11312
AC1L1GGE
AC1Q1P84
AC1Q1P85
ACHES-N-PAIN
ARONIS23835
Act-3
Actiprofen
Adex 200
Adran
Advil
Advil (TN)
Advil Liqui-Gels
Advil Liquigels
Advil Migraine
Ak+C2278tren
Alaxan
Algofen
Am-Fam 400
Amelior
Amersol
Amibufen
Anafen
Anco
Andran
Anflagen
Antagil
Antalfene
Antarene
Antiflam
Apo-Ibuprofen
Aprofen REGULAR STRENGTH
Apsifen
Apsifen-F
Artofen
Artril
Artril 300
BB_SC-1358
BIDD:GT0050
BRN 2049713
Babies R Us Ibuprofen
Babies R Us Infants Ibuprofen
Balkaprofen
Being Well Ibuprofen
Betaprofen
Bloom
Bluton
Brofen
Brufanic
Brufen
Brufen 400
Bruflam
Brufort
Buburone
Bufeno
Bufigen
Bukrefen
Bupron
Buracaps
Burana
Butylenin
C01588
C13H18O2
CCRIS 3223
CHEBI:5855
CHEMBL521
CID3672
CPD000058184
Caldolor
Cap-Profen
Care One Ibuprofen
Care One Ibuprofen Ib
Care One Ibuprofen Junior Strength
Care One Ibuprofen childrens
Care One Ibuprofen infants
Careone Ibuprofen Junior Strength
Carol
Cedaprin
Cesra
Children's Advil
Children's Elixsure
Children's Ibuprofen
Children's Motrin
Childrens Advil
Childrens Ibuprofen
Childrens Ibuprofen 100 Dye Free
Childrens Ibuprofen Oral Suspension
Childrens Motrin
Circle K Ibuprofen
Citalgan
Clear Choice Ibuprofen
Cobo
Codral
Combiflam
Conney Ibuprofen
Counteract IB
Cunil
Cvs Pharmacy Ibuprofen
D00126
D007052
DB01050
DOLO PUREN
Daiprophen
Dalsy
Dansida
Deep Relief
Dentigoa
Dg Health Ibuprofen
Dibufen
Dignoflex
Direct Safety Ibuprofen
Dolex
Dolgin
Dolgirid
Dolgit
Dolibu
Dolmaral
Dolo-Dolgit
Dolo-dolgit
Dolocyl
Dolofen
Dolofen-F
Dolofin
Dolofort
Dologel
Dolomax
Doloren
Dolormin
Doltibil
Dolven
Donjust B
Dorival
Dover Addaprin
Drin
Duafen
Duobrus
Dura-Ibu
Duralbuprofen
Dye Free Ibuprofen
Dysdolen
EU-0100691
Easifon
Ebufac
Emflam
Emflam-200
Emodin
Epobron
Eputex
Equaline Childrens Ibuprofen
Equaline Ibuprofen
Equaline Ibuprofen childrens
Equate Ibuprofen
Equate Ibuprofen childrens
Ergix
Esprenit
Exneural
Family Wellness Childrens Ibuprofen
Faspic
Femadon
Femafen
Femapirin
Femidol
Fenbid
Fenbid Spansule
Fendol
Fenspan
Fibraflex
Film Coated Ibuprofen
Formu Care Ibuprofen
Formu Care Ibuprofen childrens
Fulton Street Market Ibuprofen
Gelufene
Gofen
Good Neighbor Pharmacy Childrens Ibuprofen
Good Neighbor Pharmacy Ibuprofen
Good Neighbor Pharmacy Ibuprofen childrens
Good Sense Childrens Ibuprofen Oral Suspension
Good Sense Ibuprofen
Good Sense Ibuprofen Childrens
Good Sense Ibuprofen childrens
Good Sense Ibuprofen infants
Green Guard Ibupro Relief
Green Guard Ibuprofen Relief
Grefen
Gynofug
HMS1920F15
HMS2089P05
HMS2091N03
HMS502M09
HSDB 3099
Haltran
Harmon Face Values Ibuprofen
Health Mart Childrens Ibuprofen
Health Mart Ibuprofen
Health Mart Ibuprofen Ib
Health Sense Infants Ibuprofen Oral Suspension
Health Sense Provil
Healthy Accents Ibuprofen
Healthy Accents Ibuprofen childrens
Healthy Accents Ibuprofen infants
Help I Have An Aching Body
Henry Schein Ibuprofen
I 4883
I01-7039
I0415
I4883_SIGMA
I7905_SIAL
IB-100
IDI1_000887
IP 82
IP-82
IP82
Ibol
Ibren
Ibu
Ibu-Attritin
Ibu-Slo
Ibu-Tab
Ibu-Tab 200
Ibu-attritin
Ibu-slo
Ibu-slow
Ibubest
Ibubeta
Ibucasen
Ibudol
Ibudolor
Ibufen
Ibuflamar
Ibufug
Ibugel
Ibugen
Ibugesic
Ibuhexal
 
Ibulagic
Ibular
Ibulav
Ibuleve
Ibulgan
Ibumed
Ibumerck
Ibumetin
Ibupirac
Ibuprin
Ibuprocin
Ibuprofen
Ibuprofen (NSAID) Pain Releiver/ Fever Reducer
Ibuprofen (nsaid) Pain Reliever/fever Reducer
Ibuprofen 200
Ibuprofen Caplet
Ibuprofen Childrens
Ibuprofen Dye-Free
Ibuprofen IMMEDIATE RELEASE
Ibuprofen Ib
Ibuprofen Immediate release
Ibuprofen Infants
Ibuprofen Junior
Ibuprofen Junior Strength
Ibuprofen Pain Releiver/ Fever Reducer
Ibuprofen Pain Reliever/ Fever Reducer
Ibuprofen Pain Reliever/Fever Reducer
Ibuprofen Pain Reliever/fever Reducer
Ibuprofen Softgels
Ibuprofen childrens
Ibuprofen infants
Ibuprofen junior strength
Ibuprofene
Ibuprofeno
Ibuprofenum
Ibuprohm
Ibuprophen
Ibusal
Ibutab
Ibutid
Ifen
Inabrin
Infants Advil
Infants Dye-free Ibuprofen
Infants Ibuprofen
Infants Motrin
Inflam
Inoven
Ipren
Irfen
Isodol
Jenaprofen
Junifen
Junior Strength Advil
Junior Strength Ibuprofen
Junior Strength Motrin
KBio1_000887
KBio2_001329
KBio2_003897
KBio2_006465
KBio3_001390
Kesan
Kirkland Signature Ibuprofen
Kirkland Signature Ibuprofen Ib
Kratalgin
LS-7454
Lamidon
Leader Childrens Ibuprofen
Leader Ibuprofen
Leader Ibuprofen 200
Leader Ibuprofen Childrens
Leader Ibuprofen Infants
Lebrufen
Librofem
Lidifen
Lil Drug Store Ibuprofen
Liptan
Lopane
MLS000069733
MLS001146965
Major Childrens Ibuprofen
Malafene
Manypren
Medi-first Ibuprofen
Medi-first Plus Ibuprofen
Medipren
Medique Iprin
Melfen
Mensoton
Midol
Midol 200
Moment
Moore Medical Llc Ibuprofen
Motrin
Motrin (TN)
Motrin IB
Motrin Ib
Motrin Infants
Mynosedin
NCI60_002065
NINDS_000887
NSC 256857
NSC256857
Nagifen-D
Napacetin
Narfen
Neo-Helvagit
Neo-Mindol
NeoProfen
Neobrufen
Neoprofen
Nerofen
Noalgil
Nobafon
Nobfelon
Nobfen
Nobgen
Noritis
Norton
Novadol
Novo-Profen
Novogent
Novogent N
Novoprofen
Nuprilan
Nuprin
Nurofen
Optifen
Opturem
Oralfene
Ostarin
Ostofen
Otis Clapp Ultraprin
Ozonol
P-Isobutylhydratropic Acid
Paduden
Pain Relief
Pain Relief Anti Inflammatory
Pain Relief Ibuprofen
Panafen
Pantrop
Para-Isobutylhydratropic Acid
Paxofen
Pedia-Profen
PediaProfen
Pediacare Childrens
Pediacare Infants
Pediaprofen
Pediatric Advil
Perofen
Perrigo Ibuprofen
Physicianscare Ibuprofen
Preferred Plus Ibuprofen
Preferred Plus Ibuprofen 200
Proartinal
Probufen
Profen
Profen Ib
Profen Ib childrens
Profen Ib infants
Proflex
Proprinal
Provon
Quadrax
Quality Choice Ibuprofen 200
R.D. 13621
RD 13621
Rafen
Ranofen
Rebugen
Relcofen
Rexall Ibuprofen
Rhinadvil
Rofen
Roidenin
Rufen
Rufin
Rupan
Rx Act Ibuprofen
Rx Act Ibuprofen childrens
SAM002264619
SMR000058184
SPBio_000178
STK177358
Sadefen
Salivia
Salprofen
Seclodin
Sednafen
Seklodin
Seskafen
Shoprite Childrens Ibuprofen
Shoprite Ibuprofen
Shoprite Ibuprofen Ib
Shoprite Ibuprophen
Shoprite Infants Ibuprofen
Simply Right Ibuprofen
Siyafen
Smart Sense Ibuprofen
Smart Sense Ibuprofen gluten free
Smart Sense Ibuprofen infants
Solpaflex
Solufen
Stelar
Sugafen
Sunmark Ibuprofen
Sunmark Ibuprofen Ib
Sunmark Ibuprofen childrens
Sunmark Ibuprofen infants
Suprafen
Suspren
Syntofene
TL8001184
Tab-Profen
Tabalon
Tabalon 400
Tatanal
Tempil
Tofen
Togal N
Tonal
Topcare Childrens Ibuprofen
Topcare Ibuprofen
Topcare Ibuprofen Junior Strength
Topcare Ibuprofen childrens
Topcare Infants Ibuprofen
Trendar
U 18573
U-18,573
U-18573
UCB 79171
Unipron
Upfen
Uprofen
Urem
VUFB 9649
Welby Health Ibuprofen
Zafen
Zofen
alpha-(4-Isobutylphenyl)propionate
alpha-(4-Isobutylphenyl)propionic acid
alpha-(P-Isobutylphenyl)propionic acid
alpha-p-Isobutylphenylpropionate
alpha-p-Isobutylphenylpropionic acid
ibuprofen
p-Isobutyl-2-phenylpropionate
p-Isobutyl-2-phenylpropionic acid
p-Isobutylhydratropate
p-Isobutylhydratropic acid
8
KetorolacapprovedPhase 4, Phase 227866635-83-43826
Synonyms:
(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(+-)-Ketorolac
(+-)-isomer
(.+/-.)-2,3-Dihydro-5-benzoyl-1H-pyrrolizine-1-carboxylic acid
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro
5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
5-Benzoyl-1,2-dihydro-3H-pyrrolo(1,2a)pyrrole-1-carboxylic acid
5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
66635-83-4
74103-06-3
AB00053682
AC-545
AC1L1GSW
Acular
Acuvail
BRD-A40639672-234-05-7
C07062
CHEBI:105080
CHEMBL469
CID3826
D020910
D08104
DB00465
 
I14-2832
Ketoralac
Ketorolac
Ketorolac (INN)
Ketorolac Tromethamine
Ketorolac [INN:BAN]
Ketorolaco
Ketorolaco [Spanish]
Ketorolacum
Ketorolacum [Latin]
Kétorolac
LS-139094
Macril
MolPort-005-933-093
NCGC00185990-01
RS 37619
RS-37619
SBB067312
STL018674
Sprix
Toradol (TN)
UNII-YZI5105V0L
ketorolac
rac-Ketorolac
9
Caffeineapproved, NutraceuticalPhase 4, Phase 3, Phase 233958-08-22519
Synonyms:
07E4FB58-FD79-4175-8E3D-05BF96954522
1,3,7-Trimethyl-2,6-dioxopurine
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
1,3,7-Trimethylpurine-2,6-dione
1,3,7-Trimethylxanthine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-3-7-TRIMETHYLXANTHINE
1-Methyl-Theobromine
1-methyltheobromine
137X
1gfz
1l5q
1l7x
27602_FLUKA
2a3b
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
3,7-dihydro-1,3,7-trimethyl-1H-purine
5-26-13-00558 (Beilstein)
58-08-2
7-Methyl Theophylline
7-Methyltheophylline
7-methyltheophylline
71701-02-5
75035_FLUKA
95789-13-2
A.S.A. and Codeine Compound
AC-12774
AC1L1DV2
AC1Q3Z23
ACon1_000085
AI3-20154
AKOS000121334
Alert
Alert-Pep
Alert-pep
Allertness Aid
Anacin Maximum Strength
Anhydrous caffeine
Anhydrous caffeine (JP15)
Anhydrous caffeine (TN)
Anoquan
Awake
BIDD:ER0554
BIDD:GT0632
BIDD:PXR0172
BIM-0050216.0001
BRD-K02404261-001-02-7
BRD-K02404261-001-03-5
BRN 0017705
BSPBio_001921
Berlin-Chemie Brand of Caffeine
Bio-0579
Bio1_000473
Bio1_000962
Bio1_001451
Bristol-Myers Squibb Brand of Caffeine
C 0750
C07481
C0750_SIAL
C1778_SIAL
C2042
C6035_FLUKA
C6035_SIGMA
C7731_SIAL
C8960_SIAL
CCRIS 1314
CFF
CHEBI:27732
CHEMBL113
CID2519
CU-01000012617-3
Cafamil
Cafcit
Cafecon
Cafeina
Cafergot
Cafeína
Caffedrine
Caffedrine Caplets
Caffein
Caffeina
Caffeina [Italian]
Caffeine
Caffeine (USP)
Caffeine (natural)
Caffeine Citrate
Caffeine Pure
Caffeine [BAN:JAN]
Caffeine citrate
Caffeine solution
Caffeine, Anhydrous
Caffeine, Monohydrate
Caffeine, Synthetic
Caffeine, anhydrous
Caffeine, synthetic
Caffine
Cafipel
Caféine
Circle K Nosnooze
Coffein
Coffein [German]
Coffeine
Coffeinum
Coffeinum N
Coffeinum Purrum
Compound 65
Conrx Alert
D002110
D00528
DB00201
DHC Plus
DHCplus
Darvon Compound
Darvon Compound-65
Dasin
Dexitac
Dexitac Stay Alert Stimulant
Dhc Plus
Diurex
Diurex Ultra
Diurex WaterCaps
DivK1c_000730
Drowz Away Maximum strength
Durvitan
EINECS 200-362-1
EU-0100228
Eldiatric C
Enerjets
Equaline Stay Awake
Ercatab
Esgic
Esgic-Plus
FEMA No. 2224
Femcet
Fioricet
Fiorinal
GlaxoSmithKline Brand of Caffeine
Good Neighbor Pharmacy Stay Awake
Good Sense Stay Awake
Guaranine
HMS1920I09
HMS2091O11
HMS502E12
HSDB 36
Health Mart Stay Awake
Healthy Accents Stay Awake
Hycomine
Hycomine Compound
I14-4386
IDI1_000730
 
Invagesic
Invagesic Forte
KBio1_000730
KBio2_001781
KBio2_004349
KBio2_006917
KBio3_001141
KBioGR_002325
KBioSS_001781
Keep Alert
Kofein
Kofein [Czech]
Koffein
Koffein [German]
L000155
LS-237
Lanorinal
Leader Alertness Aid
Lil Drug Store Nosnooze
Lopac-C-0750
Lopac0_000228
MEGxp0_001350
MLS001055341
MLS001056714
MLS001066409
Mateina
Mateína
Maximum Strength Caffeine
Maximum Strength Snapback Stimulant Powders
Maximum Strength Stay Awake
Medigesic Plus
Merck dura Brand of Caffeine
Methyltheobromide
Methyltheobromine
Methylxanthine theophylline
Midol Maximum Strength
Migergot
Miudol
MolMap_000054
MolPort-000-730-850
Monohydrate Caffeine
Monomethyl Derivative of Theophylline
Monomethyl derivative of Theophylline
NCGC00015208-01
NCGC00015208-02
NCGC00015208-04
NCGC00015208-14
NCGC00090699-01
NCGC00090699-02
NCGC00090699-03
NCGC00090699-04
NCGC00090699-05
NCGC00090699-06
NCGC00090699-07
NCGC00090699-08
NCGC00090699-09
NCGC00168808-01
NCGC00168808-02
NCI-C02733
NCIOpen2_008255
NINDS_000730
NSC 5036
NSC5036
Nano Ppc
Natural Caffeinum
Nix Nap
No Doz
No-Doz
Nodaca
Nodoz Maximum Strength Caplets
Norgesic
Norgesic Forte
Organex
Orphengesic
Orphengesic Forte
P-A-C Analgesic Tablets
PDSP1_001016
PDSP1_001235
PDSP2_001000
PDSP2_001219
Passauer Brand of Caffeine
Pep-Back
Pep-back Peak Performance
Pep-back Ultra
Percoffedrinol N
Percutafeine
Phensal
Pierre Fabre Brand of Caffeine
Probes1_000150
Probes2_000128
Propoxyphene
Propoxyphene Compound 65
Propoxyphene Compound-65
Quick Pep
Quick-Pep
Refresh'n
Republic Drug Brand of Caffeine
SDCCGMLS-0064595.P001
SDCCGMLS-0064595.P002
SK 65 Compound
SK-65 Compound
SMR000326667
SPBio_001222
SPECTRUM1500155
STK177283
Seid Brand of Caffeine
Smart Sense Stay Awake
Sohmed Alertness Aid
Spectrum2_001261
Spectrum3_000321
Spectrum4_001782
Spectrum5_000423
Spectrum_001301
Stay Alert Aid
Stay Awake
Stay Awake Maximum Strength
Stay Awake Maximum strength
Stim
Sunmark Stay Awake
Synalgos-Dc
TNP00310
Teina
Thein
Theine
Theobromine ME
Theobromine Me
Theophylline ME
Theophylline Me
Theophylline, 7-methyl
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Tirend
Topcare Stay Awake maximum strength
Tri-Aqua
Triad
UNII-3G6A5W338E
Ultra Pep-Back
Vivarin
W222402_ALDRICH
WLN: T56 BN DN FNVNVJ B1 F1 H1
Wake-Up
Wigraine
Xanthine, 1,3,7-trimethyl
ZINC00001084
bmse000206
cafeine
caffeine
caffenium
component of Cafergot
nchembio.243-comp7
nchembio.63-comp5
nchembio774-comp2
teina
10
Vitamin Aapproved, nutraceuticalPhase 4, Phase 341311103-57-4, 68-26-8445354
Synonyms:
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol
(2e,4e,6e,8e)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
.alpha.lin
.alpha.sterol
.beta.-Retinol
11103-57-4
13123-33-6
1341-18-0
1406-67-3
17104-91-5
1rbp
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,4,6,8-nonatetraen-1-ol
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonate-traen-1-ol
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraen-1-ol
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-E)-Isomer
4-06-00-04133 (Beilstein Handbook Reference)
53637-36-8
5979-23-7
68-26-8
95144_FLUKA
95144_SIGMA
95146_FLUKA
95146_SIGMA
A-Mulsal
A-Sol
A-Vi-Pel
A-Vitan
AC-11701
AC1L9HU3
AC1Q7BU9
ACON
ALL-TRANS RETINOL (SEE ALSO RETINOID PROJECT 1)
AR-1L3057
ATAV
Afaxin
Agiolan
Agoncal
Alcohol 9,13-dimethyl-7-(1,1,5-trimethyl-6-cyclohexen-5-yl)-7,9,11,13-nonatetraen-15-ol
Alcovit A
All Trans Retinol
All-trans retinol
All-trans-Retinol
Alphalin
Alphasterol
Anatola
Anatola A
Anti-infective vitamin
Antixerophthalmic vitamin
Antixerophthalmisches Vitamin
Aoral
Apexol
Apostavit
Aquasol A
Aquasol A Parenteral
Aquasynth
Atars
Avibon
Avita
Avitol
Axerol
Axerophthol
Axerophtholum
BIDD:PXR0102
BRN 0403040
Bentavit A
Biosterol
C00473
C17276
C20H30O
CCRIS 5444
CHEBI:17336
CHEMBL986
CID445354
Chocola A
Chocola a
Cylasphere
D014801
D06543
DB00162
Del-VI-A
Disatabs Tabs
Dofsol
Dohyfral A
EINECS 200-683-7
EINECS 234-328-2
Epiteliol
HMS1921B04
HMS2092L13
HMS501I08
HSDB 815
Hi-A-Vita
Homagenets Aoral
Homagenets aorl
Hydrovit A
IDI1_000486
LMPR01090001
LPK
LS-1578
Lard Factor
M.V.C. 9+3
M.V.I.-12
 
MLS001066379
MLS001074751
MolPort-001-785-962
Mvc Plus
Myvpack
NCGC00091784-01
NCGC00091784-02
NCGC00091784-03
NCGC00091784-04
NCGC00091784-05
NCGC00091784-06
NSC 122759
NSC122759
Nio-A-Let
Oleovitamin A
Ophthalamin
Plivit A
Prepalin
R7632_SIGMA
Retin-11,12-t2-ol (9CI)
Retinol
Retinol [INN:BAN]
Retinol solution
Retinol, all-trans- (8CI)
Retinol-(cellular-retinol-binding-protein)
Retinolo
Retinolo [DCIT]
Retinolum
Retinolum [INN-Latin]
Retrovitamin A
Ro-a-vit
Rovimix A 500
SDCCGMLS-0066724.P001
SMP2_000102
SMR000112036
SPECTRUM1501203
ST057232
Sehkraft A
Solu-A
Spectrum5_000993
Spectrum5_001997
Super A
Testavol
Testavol S
Thalasphere
UNII-81G40H8B0T
UNII-G2SH0XKK91
Vaflol
Vafol
Veroftal
Vi-.alpha.
Vi-Alpha
Vi-Dom-A
Vi-a
Vio-A
Vitamin A
Vitamin A (Feed)
Vitamin A (USP)
Vitamin A alcohol
Vitamin A alcohol (VAN)
Vitamin A cryst
Vitamin A palmitate
Vitamin A1
Vitamin A1 alcohol
Vitamin A1 alcohol, all trans
Vitamin a
Vitamin- A
Vitamin- A alcohol
Vitamin- A alcohol solution
Vitamin- A1
Vitamin-?A
Vitamin-?A alcohol
Vitamin-?A alcohol solution
Vitamin-?A1
Vitamine A
Vitaminum A
Vitavel A
Vitavel-A
Vitpex
Vogan
Vogan-Neu
Vogan-nu
WLN: L6UTJ A1 B1U1Y1&U2U1Y1&U2Q C1 C1
Wachstumsvitamin
ZINC03831417
Zinosan N
[11,12-3H]-Retinol
alin
all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
all-trans-Retinol
all-trans-Retinyl alcohol
all-trans-Vitamin A
all-trans-Vitamin A alcohol
all-trans-Vitamin A1
all-trans-retinol
all-trans-retinyl alcohol
all-trans-vitamin A alcohol
b-Retinol
beta-Retinol
retinol
tROL
trans-Retinol
trans-Retinol acid (Vitamin A)
trans-Vitamin A alcohol
trans-retinol
11Purinergic P1 Receptor AntagonistsPhase 4, Phase 3, Phase 2262
12Angiogenesis InhibitorsPhase 4, Phase 3, Phase 2, Phase 13688
13VitaminsPhase 4, Phase 3, Phase 23857
14Phosphodiesterase InhibitorsPhase 4, Phase 3, Phase 21062
15Caffeine citratePhase 4, Phase 3, Phase 217
16Central Nervous System StimulantsPhase 4, Phase 3, Phase 21721
17AnalgesicsPhase 4, Phase 3, Phase 29358
18Immunologic FactorsPhase 4, Phase 3, Phase 218483
19Antirheumatic AgentsPhase 4, Phase 3, Phase 28496
20Cyclooxygenase InhibitorsPhase 4, Phase 3, Phase 22225
21Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 28478
22Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 25184
23Angiogenesis Modulating AgentsPhase 4, Phase 2, Phase 3, Phase 13611
24Respiratory System AgentsPhase 4, Phase 2, Phase 3, Phase 13931
25Tocolytic AgentsPhase 4, Phase 3561
26Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 3, Phase 23549
27Trace ElementsPhase 4, Phase 3, Phase 23900
28Anesthetics, InhalationPhase 4, Phase 3511
29Neurotransmitter AgentsPhase 4, Phase 2, Phase 3, Phase 114795
30Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 118510
31Neuromuscular Blocking AgentsPhase 4327
32Hypnotics and SedativesPhase 42032
33Central Nervous System DepressantsPhase 4, Phase 310016
34Excitatory Amino Acid AntagonistsPhase 41095
35Excitatory Amino AcidsPhase 41109
36Anesthetics, IntravenousPhase 41943
37Platelet Aggregation InhibitorsPhase 4, Phase 31935
38Protective AgentsPhase 4, Phase 2, Phase 3, Phase 15651
39AnestheticsPhase 4, Phase 2, Phase 37385
40Retinol palmitatePhase 4, Phase 3413
41MicronutrientsPhase 4, Phase 3, Phase 23901
42Anesthetics, DissociativePhase 4417
43AntioxidantsPhase 4, Phase 2, Phase 3, Phase 12442
44Endothelial Growth FactorsPhase 4, Phase 1, Phase 2328
45Anesthetics, GeneralPhase 4, Phase 32274
46MitogensPhase 4, Phase 1, Phase 21386
47Ketorolac TromethaminePhase 4, Phase 2278
48Poractant alfaPhase 423
49Pulmonary SurfactantsPhase 4, Phase 3, Phase 2101
50retinolNutraceuticalPhase 4, Phase 3413

Interventional clinical trials:

(show top 50)    (show all 162)
idNameStatusNCT IDPhase
1Sucrose Analgesia for the Reduction of Pain During Retinopathy of Prematurity ScreeningCompletedNCT00921544Phase 4
2Anesthesia for Retinopathy of PrematurityCompletedNCT01955135Phase 4
3Vascular Endothelial Growth Factor in Stage V ROPCompletedNCT00500396Phase 4
4VEGF Levels in Aqueous, Vitreous and Subretinal Fluid in ROP Stage IV and VCompletedNCT00563121Phase 4
5Vitamin A and Very Low Birthweight Babies (VitAL)CompletedNCT00417404Phase 4
6MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose CaffeineCompletedNCT00809055Phase 4
7Safety and Tolerability of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular DegenerationCompletedNCT00504959Phase 4
8Early CPAP in Respiratory Distress SyndromeRecruitingNCT00368680Phase 4
9Withholding Feeds During Red Blood Cell Transfusion and TRAGIRecruitingNCT02132819Phase 4
10OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAPRecruitingNCT02140580Phase 4
11Cpap at Delivery Room for Preterm InfantsActive, not recruitingNCT01024361Phase 4
12Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in PrematurityEnrolling by invitationNCT00634972Phase 4
13Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus in Very Premature BabiesWithdrawnNCT00470743Phase 4
14A Fatty Acids Study in Preventing Retinopathy of PrematurityCompletedNCT02760472Phase 3
15Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of PrematurityCompletedNCT01203436Phase 2, Phase 3
16Safety and Efficacy of Propranolol in Newborns With Retinopathy of PrematurityCompletedNCT01079715Phase 2, Phase 3
17The Effects of Light Reduction on Retinopathy of Prematurity (Light-ROP)CompletedNCT00000156Phase 3
18Inhaled Nitrous Oxide for Pain Relief During Eye Exam in the Pre-term InfantCompletedNCT00623220Phase 3
19Premature Infants in Need of Transfusion (PINT)CompletedNCT00182390Phase 3
2017OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet PregnanciesCompletedNCT00163020Phase 2, Phase 3
21NIV Strategies for RDS in Preterm Infants. NIV (Non Invasive Ventilation), RDS (Respiratory Distress Syndrome)CompletedNCT02259400Phase 2, Phase 3
22Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams BirthweightCompletedNCT00734539Phase 3
23Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk PregnanciesCompletedNCT00135902Phase 3
24Oxygen Toxicity in the Resuscitation in Extremely Premature InfantsCompletedNCT00494702Phase 3
25Nasal Intermittent Positive Pressure Ventilation in Premature Infants (NIPPV)CompletedNCT00433212Phase 3
26High Versus Low Dose of Caffeine for Apnea of PrematurityCompletedNCT02103777Phase 3
27Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)CompletedNCT00099164Phase 3
28Inhaled Nitric Oxide to Prevent and Treat Bronchopulmonary DysplasiaCompletedNCT01503801Phase 2, Phase 3
29Canadian Oxygen Trial (COT)CompletedNCT00637169Phase 3
30Pentoxifylline and Late Onset Sepsis in Preterm InfantsCompletedNCT02163174Phase 3
31Safety and Efficacy Study of Ibuprofen l-Lysine Solution in Premature Infants for Treatment of PDACompletedNCT00440804Phase 3
32Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth WeightCompletedNCT00114543Phase 3
33Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)CompletedNCT00009646Phase 3
34Prevention Trial of Nosocomial Infections in Neutropenic Prematures With G-CSFCompletedNCT00213759Phase 3
35RAINBOW Study: RAnibizumab Compared With Laser Therapy for the Treatment of INfants BOrn Prematurely With Retinopathy of PrematurityRecruitingNCT02375971Phase 3
36Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural OutcomeRecruitingNCT00346814Phase 2, Phase 3
37Oral Vitamin A Supplementation in Neonates With Birth Weight < 1500 gRecruitingNCT02102711Phase 3
38Maternal Omega-3 Supplementation to Reduce Bronchopulmonary DysplasiaRecruitingNCT02371460Phase 3
39A Randomized Trial to Prevent Congenital Cytomegalovirus (CMV)RecruitingNCT01376778Phase 3
40Randomized Study of Pessary Versus Standard Management in Women With Increased Chance of Premature BirthRecruitingNCT00735137Phase 3
41The Early Treatment for Retinopathy of Prematurity Study (ETROP)Active, not recruitingNCT00027222Phase 2, Phase 3
42Surfactant Positive Airway Pressure and Pulse Oximetry TrialActive, not recruitingNCT00233324Phase 3
43Cysteine Supplementation in Critically Ill NeonatesActive, not recruitingNCT00254176Phase 2, Phase 3
44Caffeine for Apnea of Prematurity (CAP)Active, not recruitingNCT00182312Phase 3
45High Dose Folic Acid Supplementation Throughout Pregnancy for Preeclampsia PreventionActive, not recruitingNCT01355159Phase 3
46L-Thyroxine Supplementation for Preterm Newborns Less Than 32 Weeks of Gestation With HypothyroxinemiaActive, not recruitingNCT01306227Phase 3
47Rainbow Extension StudyNot yet recruitingNCT02640664Phase 3
48Efficacy and Safety of Goat Lung Surfactant for the Treatment of Respiratory Distress Syndrome in Preterm NeonatesNot yet recruitingNCT02774044Phase 2, Phase 3
49Comparison of Two Flow Rates of HHHFNC to Prevent Extubation Failure in Preterm InfantsNot yet recruitingNCT02681315Phase 3
50Sildenafil Therapy In Dismal Prognosis Early-Onset Intrauterine Growth RestrictionNot yet recruitingNCT02442492Phase 2, Phase 3

Search NIH Clinical Center for Exudative Vitreoretinopathy 1


Cochrane evidence based reviews: retinopathy of prematurity

Genetic Tests for Exudative Vitreoretinopathy 1

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Genetic tests related to Exudative Vitreoretinopathy 1:

id Genetic test Affiliating Genes
1 Familial Exudative Vitreoretinopathy, Autosomal Dominant22 TSPAN12
2 Retinopathy of Prematurity22 FZD4

Anatomical Context for Exudative Vitreoretinopathy 1

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MalaCards organs/tissues related to Exudative Vitreoretinopathy 1:

33
Eye, Retina, Lung, Endothelial, Skin, Testes, Liver

Animal Models for Exudative Vitreoretinopathy 1 or affiliated genes

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MGI Mouse Phenotypes related to Exudative Vitreoretinopathy 1:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053809.2EPO, FLT1, FZD4, KDR, LRP5, SERPINH1
2MP:00028739.2EPO, FLT1, FZD4, IGF1, KDR, LRP5
3MP:00053699.1ATP7B, FLT1, FZD4, IGF1, KDR, TEK
4MP:00053919.0ANGPT2, FLT1, FZD4, KDR, LRP5, NDP
5MP:00036318.3ATP7B, FLT1, FZD4, IGF1, KDR, LRP5
6MP:00053977.8ATP7B, CD38, EPO, FLT1, FZD4, IGF1
7MP:00053857.7ANGPT2, EPO, FLT1, FZD4, IGF1, KDR
8MP:00053767.6ANGPT2, ATP7B, CD38, EPO, FLT1, FZD4
9MP:00107687.5ANGPT2, ATP7B, CPVL, EPO, FLT1, FZD4

Publications for Exudative Vitreoretinopathy 1

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Variations for Exudative Vitreoretinopathy 1

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UniProtKB/Swiss-Prot genetic disease variations for Exudative Vitreoretinopathy 1:

67 (show all 20)
id Symbol AA change Variation ID SNP ID
1FZD4p.Met105ValVAR_038947
2FZD4p.Met157ValVAR_038948
3FZD4p.Pro33SerVAR_063920rs61735304
4FZD4p.Gly36AspVAR_063921
5FZD4p.Glu40GlnVAR_063922rs139401671
6FZD4p.His69TyrVAR_063923rs80358282
7FZD4p.Met105ThrVAR_063924
8FZD4p.Ile114ThrVAR_063925
9FZD4p.Cys181ArgVAR_063927
10FZD4p.Cys204ArgVAR_063929
11FZD4p.Cys204TyrVAR_063930
12FZD4p.Met223LysVAR_063931
13FZD4p.Ile256ValVAR_063932
14FZD4p.Trp335CysVAR_063933
15FZD4p.Met342ValVAR_063934rs80358293
16FZD4p.Arg417GlnVAR_063936
17FZD4p.Thr445ProVAR_063937
18FZD4p.Gly488AspVAR_063938
19FZD4p.Ser497PheVAR_063939
20FZD4p.Gly525ArgVAR_063940

Clinvar genetic disease variations for Exudative Vitreoretinopathy 1:

5
id Gene Variation Type Significance SNP ID Assembly Location
1NM_012193.3(FZD4): c.1479_1484delGTGGAT (p.Met493_Trp494del)deletionPathogenicrs80358301GRCh37Chr 11, 86662314: 86662319
2NM_012193.3(FZD4): c.1501_1502delCT (p.Leu501Serfs)deletionPathogenicrs80358303GRCh37Chr 11, 86662296: 86662297
3NM_012193.3(FZD4): c.1250G> A (p.Arg417Gln)single nucleotide variantPathogenicrs80358294GRCh37Chr 11, 86662548: 86662548
4NM_012193.3(FZD4): c.1024A> G (p.Met342Val)single nucleotide variantPathogenicrs80358293GRCh37Chr 11, 86662774: 86662774
5NM_012193.3(FZD4): c.1005G> C (p.Trp335Cys)single nucleotide variantPathogenicrs80358292GRCh37Chr 11, 86662793: 86662793

Expression for genes affiliated with Exudative Vitreoretinopathy 1

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Search GEO for disease gene expression data for Exudative Vitreoretinopathy 1.

Pathways for genes affiliated with Exudative Vitreoretinopathy 1

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GO Terms for genes affiliated with Exudative Vitreoretinopathy 1

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Biological processes related to Exudative Vitreoretinopathy 1 according to GeneCards Suite gene sharing:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1cell migration involved in sprouting angiogenesisGO:000204210.7KDR, VEGFA
2positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathwayGO:003803310.7KDR, VEGFA
3positive regulation of tyrosine phosphorylation of Stat5 proteinGO:004252310.6EPO, IGF1
4positive regulation of mesenchymal cell proliferationGO:000205310.6LRP5, VEGFA
5positive regulation of focal adhesion assemblyGO:005189410.5KDR, TEK
6placenta developmentGO:000189010.5CDKN1C, NDP
7regulation of transcription from RNA polymerase II promoter in response to hypoxiaGO:006141810.5EPO, VEGFA
8Tie signaling pathwayGO:004801410.5ANGPT2, TEK
9substrate adhesion-dependent cell spreadingGO:003444610.4FZD4, TEK
10canonical Wnt signaling pathwayGO:006007010.3FZD4, LRP5, NDP
11negative regulation of protein serine/threonine kinase activityGO:007190110.3CDKN1C, LRP5
12peptidyl-tyrosine phosphorylationGO:001810810.2FLT1, KDR, TEK
13cellular response to vascular endothelial growth factor stimulusGO:003592410.1FLT1, VEGFA
14positive regulation of phosphatidylinositol 3-kinase signalingGO:00140689.9FLT1, IGF1, KDR, TEK
15Wnt signaling pathwayGO:00160559.7FZD4, LRP5, NDP
16positive regulation of angiogenesisGO:00457669.6ANGPT2, FLT1, KDR, TEK, VEGFA
17angiogenesisGO:00015259.5KDR, TEK, TSPAN12, VEGFA
18response to hypoxiaGO:00016669.4ANGPT2, CD38, EPO, FLT1, IGF1
19negative regulation of apoptotic processGO:00430669.3CD38, EPO, IGF1, KDR, TEK, VEGFA

Sources for Exudative Vitreoretinopathy 1

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet