MCID: FCL012
MIFTS: 38

Facial Paralysis malady

Summaries for Facial Paralysis

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MalaCards based summary: Facial Paralysis, also known as facial palsy, is related to acoustic neuroma and neurofibromatosis, type 2. An important gene associated with Facial Paralysis is HOXB1 (homeobox B1). The drugs scopolamine and scopolamine hydrobromide have been mentioned in the context of this disorder. Affiliated tissues include bone, eye and skin, and related mouse phenotype endocrine/exocrine gland.

Aliases & Classifications for Facial Paralysis

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Facial Paralysis, Aliases & Descriptions:

Name: Facial Paralysis 10 12 62
 
Facial Palsy 10


External Ids:

Disease Ontology10 DOID:13934
NCIt40 C26769
MeSH35 D005158

Related Diseases for Facial Paralysis

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Diseases related to Facial Paralysis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 245)
idRelated DiseaseScoreTop Affiliating Genes
1acoustic neuroma30.6FKBP4
2neurofibromatosis, type 230.3CADM1, NF2
3breast cancer29.9FKBP4, CADM1, NF2, CD82
4bell's palsy10.7
5otitis media10.5
6recurrent peripheral facial palsy10.4
7bone fracture10.4
8hemifacial spasm10.4
9parotitis10.3
10ectropion10.3
11herpes simplex10.3
12neuroma10.3
13melkersson-rosenthal syndrome10.3
14cholesteatoma10.3
15ptosis10.3
16craniometaphyseal dysplasia10.3
17deafness - ear malformation - facial palsy10.3
18moebius syndrome10.2
19lagophthalmos10.2
20meningitis10.2
21congenital hereditary facial paralysis with variable hearing loss10.2
22anotia10.2
23urofacial syndrome 110.2
24osteopathia striata with cranial sclerosis10.2
25tolosa-hunt syndrome10.2
26chickenpox10.2
27panuveitis10.2
28anotia facial palsy cardiac defect10.2
29deafness conductive stapedial ear malformation facial palsy10.2
30johnson neuroectodermal syndrome10.2
31neuroblastoma10.1
32petrositis10.1
33middle ear adenoma10.1
34adenoma10.1
35amyloidosis10.1
36labyrinthitis10.1
37neuritis10.1
38sarcoma10.1
39skull base neoplasm10.1
40suppurative otitis media10.1
41tuberculosis10.1
42familial amyloidosis, finnish type10.1
43abducens palsy10.1
44isolated hereditary congenital facial paralysis10.1
45craniometaphyseal dysplasia, autosomal recessive10.1
46lenz-majewski hyperostotic dwarfism10.1
47alexander disease10.1
48myotonic dystrophy 110.1
49peroxisome biogenesis disorder 1b10.1
50hyperostosis, endosteal10.1

Graphical network of the top 20 diseases related to Facial Paralysis:



Diseases related to facial paralysis

Symptoms for Facial Paralysis

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Drugs & Therapeutics for Facial Paralysis

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Drug clinical trials:

Search ClinicalTrials for Facial Paralysis

Search NIH Clinical Center for Facial Paralysis

Inferred drug relations via UMLS62/NDF-RT41:

Genetic Tests for Facial Paralysis

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Anatomical Context for Facial Paralysis

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MalaCards organs/tissues related to Facial Paralysis:

33
Bone, Eye, Skin, Heart, Breast, Testes, Brain, Cortex, Liver, Myeloid, Tongue

Animal Models for Facial Paralysis or affiliated genes

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MGI Mouse Phenotypes related to Facial Paralysis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.4NF2, CADM1, FKBP4, HOXB1

Publications for Facial Paralysis

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Articles related to Facial Paralysis:

(show top 50)    (show all 552)
idTitleAuthorsYear
1
One-stage dual latissimus dorsi muscle flap transfer with a pair of vascular anastomoses and double nerve suturing for long-standing facial paralysis. (25819029)
2015
2
Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer. (25868011)
2015
3
Recycle of temporal muscle in combination with free muscle transfer in the treatment of facial paralysis. (23283482)
2013
4
State of the art in treatment of facial paralysis with temporalis tendon transfer. (23842289)
2013
5
Facial paralysis and mediastinitis due to odontogenic infection and poor prognosis. (24220381)
2013
6
Use of an individual mandibular advancement device for an?obstructive sleep apnoea patient with facial paralysis: a short-term follow-up case report. (22329406)
2012
7
Facial paralysis and lymphocytic facial neuritis in a rhesus macaque (Macaca mulatta) positive for simian retrovirus type D2. (22330582)
2011
8
Peripheral facial paralysis and bilateral carotid pseudoaneurysms of petrous localization: a case report. (23984216)
2011
9
Dynamic facial prosthetics for sufferers of facial paralysis. (23386867)
2011
10
Developmental facial paralysis: a review. (21724478)
2011
11
Management and outcomes of facial paralysis from intratemporal blunt trauma: a systematic review. (21225812)
2010
12
Effect of delayed decompression after early steroid treatment on facial function of patients with facial paralysis. (19437165)
2010
13
Sir Charles Bell was not affected by facial paralysis himself! (20464311)
2010
14
Secondary surgery in paediatric facial paralysis reanimation. (20018580)
2010
15
Bilateral otitis media with facial paralysis in a Japanese black calf. (19684349)
2009
16
Outcomes of direct muscle neurotization in pediatric patients with facial paralysis. (20009835)
2009
17
Secondary surgery in adult facial paralysis reanimation. (19952647)
2009
18
Facial paralysis: research and future directions. (18470838)
2008
19
Chronic pachymeningitis and bilateral facial paralysis secondary to renal osteodystrophy. (18347262)
2008
20
Combination of hypoglossal-facial nerve jump graft by end-to-side neurorrhaphy and cross-face nerve graft for the treatment of facial paralysis. (17530609)
2007
21
Correction of ectropion in facial paralysis. (16462363)
2006
22
A comparison of commissure excursion following gracilis muscle transplantation for facial paralysis using a cross-face nerve graft versus the motor nerve to the masseter nerve. (16772949)
2006
23
Neurovascularized free short head of the biceps femoris muscle transfer for one-stage reanimation of facial paralysis. (15692342)
2005
24
Ectopic bone formation following temporalis muscle transposition for facial paralysis: a rare complication? (16186726)
2005
25
Anthropometric measurements of the endoscopic eyebrow lift in the treatment of facial paralysis. (12794455)
2003
26
Facial paralysis in Wegener's granulomatosis of the middle ear. (11276335)
2001
27
Impact of facial paralysis on patients with acoustic neuroma. (10983957)
2000
28
Reanimation of early facial paralysis with hypoglossal/facial end-to-side neurorrhaphy: a new approach. (10954315)
2000
29
The SOOF lift as an adjunct in rehabilitation of facial paralysis: help or hype? (11460300)
2000
30
Primary facial rehabilitation in facial paralysis after extirpative surgery. (11074718)
2000
31
The effect of muscle transplantation after unilateral partial facial paralysis on craniofacial growth and development: relationship between muscle and nerve histomorphometric findings. (10626980)
2000
32
New eyebrow lift technique using a semiautomatic suturing device (maniceps) for patients with facial paralysis. (11128757)
2000
33
Surgical management of the facial nerve in craniofacial trauma and long-standing facial paralysis: cadaver study and clinical presentations. (11951222)
1999
34
Temporal bone hemangioma as a cause of facial paralysis. (10089691)
1999
35
Necrotizing otitis externa, otitis media, peripheral facial paralysis, and brain abscess in a thalassemic child after allogeneic BMT. (9783316)
1998
36
Evaluating facial paralysis. Expensive diagnostic tests are often unnecessary. (9633550)
1998
37
Neurovascular free muscle transfer combined with cross-face nerve grafting for the treatment of facial paralysis in children. (9623816)
1998
38
Iatrogenic facial paralysis prevention. (8972995)
1996
39
Surgical facial nerve decompression for peripheral facial paralysis of diverse causes. (8828273)
1996
40
Symmetry and synkinesis during rehabilitation of unilateral facial paralysis. (7674438)
1995
41
Early temporalis muscle transposition for the management of facial paralysis. (7666737)
1995
42
Facial paralysis in children. (8572104)
1994
43
Long-term follow-up of nerve conduction velocity in cross-face nerve grafting for the treatment of facial paralysis. (8171133)
1994
44
Long-term results of severe facial paralysis. (10774436)
1994
45
Anti-Borrelia burgdorferi antibodies in sera of patients with facial paralysis. (10774421)
1994
46
Comments regarding prognostic significance of stapes reflex in Bell's palsy, application of electroneuronography in managing Bell's palsy, and tuberculosis of the middle ear in facial paralysis, management of an injured facial nerve following middle ear surgery. (1805644)
1991
47
Syndrome of anotia, facial paralysis, and congenital heart disease. (6470867)
1984
48
PAROTITIS AND FACIAL PARALYSIS IN MID-LINE GRANULOMA. (14256342)
1965
49
Superior petrosal and cavernous sinus thrombosis and basal petrositis; observed as complication of destructive labyrinthitis with facial paralysis. (20284480)
1947
50
The Association of Optic Neuritis, Facial Paralysis, and Facial Hemiatrophy. (16693016)
1934

Variations for Facial Paralysis

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Expression for genes affiliated with Facial Paralysis

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Search GEO for disease gene expression data for Facial Paralysis.

Pathways for genes affiliated with Facial Paralysis

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Compounds for genes affiliated with Facial Paralysis

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GO Terms for genes affiliated with Facial Paralysis

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Biological processes related to Facial Paralysis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell-cell junction organizationGO:00452169.6NF2, CADM1

Products for genes affiliated with Facial Paralysis

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  • Antibodies
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  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Facial Paralysis

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet