MCID: FCL012
MIFTS: 44

Facial Paralysis malady

Summaries for Facial Paralysis

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Facial nerve paralysis is a common problem that involves the paralysis of any structures innervated by... more...

MalaCards: Facial Paralysis, also known as facial palsy, is related to acoustic neuroma and sost-related sclerosing bone dysplasia. An important gene associated with Facial Paralysis is HOXB1 (homeobox B1). The drugs scopolamine and scopolamine hydrobromide and the compounds cytochalasin d and digitonin have been mentioned in the context of this disorder. Related mouse phenotypes are respiratory system and skeleton.

Aliases & Classifications for Facial Paralysis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 35MeSH, 40NCIt
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Aliases & Descriptions:

facial paralysis 8 10 61
facial palsy 8


External Ids:

Disease Ontology8 DOID:13934
MeSH35 D005158
NCIt40 C26769

Related Diseases for Facial Paralysis

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Facial Paralysis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 161)
idRelated DiseaseScoreTop Affiliating Genes
1acoustic neuroma30.4FKBP4
2sost-related sclerosing bone dysplasia30.1LRP5, TGFB1
3neurofibromatosis30.1CADM1, NF2
4camurati-engelmann disease29.9TGFB1, LRP5
5squamous cell carcinoma29.9GSN, CADM1, TP63, TGFB1, CD82
6idiopathic facial palsy10.6
7bell's palsy10.5
8recurrent peripheral facial palsy10.4
9bone fracture10.4
10hemifacial spasm10.4
11familial recurrent peripheral facial palsy10.4
12parotitis10.3
13melkersson-rosenthal syndrome10.3
14moebius syndrome10.3
15ramsay-hunt syndrome10.3
16deafness - ear malformation - facial palsy10.2
17hereditary congenital facial paresis 310.2
18isolated hereditary congenital facial paralysis10.2
19anotia10.2
20tolosa-hunt syndrome10.2
21anotia facial palsy cardiac defect10.2
22deafness conductive stapedial ear malformation facial palsy10.2
23malignant otitis externa10.1
24adenoma10.1
25amyloidosis10.1
26skull base neoplasm10.1
27suppurative otitis media10.1
28tuberculosis10.1
29familial amyloidosis, finnish type10.1
30abducens palsy10.1
31leptospirosis10.1
32urofacial syndrome10.1
33cutaneous anthrax10.1
34chickenpox10.1
35adult syndrome10.1
36craniometaphyseal dysplasia10.1
37mumps10.1
38hyperacusis10.1
39guillain-barr� syndrome10.1
40foot drop10.1
41myokymia10.1
42meningococcal meningitis10.1
43lattice corneal dystrophy10.0GSN
44laryngeal squamous cell carcinoma10.0TP63
45pancreatitis10.0TGFB1
46cervical squamous cell carcinoma10.0TP63
47cervical intraepithelial neoplasia10.0CADM1
48craniosynostosis10.0ANKH, LRP5
49renal osteodystrophy10.0
50osteoblastoma10.0

Graphical network of the top 20 diseases related to Facial Paralysis:



Diseases related to facial paralysis

Clinical Features for Facial Paralysis

Drugs & Therapeutics for Facial Paralysis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Facial Paralysis

Drug clinical trials:

Search ClinicalTrials for Facial Paralysis

Search NIH Clinical Center for Facial Paralysis

Search CenterWatch for Facial Paralysis

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Facial Paralysis

Anatomical Context for Facial Paralysis

Animal Models for Facial Paralysis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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Publications for Facial Paralysis

Sources:
51PubMed
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Articles related to Facial Paralysis:

(show top 50)    (show all 561)
idTitleAuthorsYear
1
Management of patients with facial paralysis in the dental office: A brief review of the literature and case report. (24392498)
2014
2
State of the art in treatment of facial paralysis with temporalis tendon transfer. (23842289)
2013
3
Facial paralysis and mediastinitis due to odontogenic infection and poor prognosis. (24220381)
2013
4
Evidence and opinion in facial plastic surgery: surgical management of facial paralysis, nasal defects, and rhinoplasty. (23799415)
2013
5
Value of electroneurography as a prognostic indicator for recovery in acute severe inflammatory facial paralysis: a prospective study of Bell's palsy and Ramsay Hunt syndrome. (23918352)
2013
6
Facial paralysis secondary to single metastasis to the temporal bone from bladder cancer. (24326243)
2013
7
Facial nerve paralysis due to chronic otitis media: prognosis in restoration of facial function after surgical intervention. (22477011)
2012
8
Use of triple-convergence polypropylene thread for the aesthetic correction of partial facial paralysis caused by the facial nerve injury. (23174786)
2012
9
Clinical management of microstomia due to the static treatment of facial paralysis and oral rehabilitation with dental implants. (21558911)
2011
10
Discussion: treatment of facial paralysis: dynamic reanimation of spontaneous facial expression-apropos of 655 patients. (22094771)
2011
11
Secondary surgery in paediatric facial paralysis reanimation. (20018580)
2010
12
Facial paralysis: a critical review of accepted explanation. (19910126)
2010
13
Reanimation of reversible facial paralysis by the double innervation technique using an intraneural-dissected sural nerve graft. (19995687)
2010
14
Long-term results for the use of gold eyelid load weights in the management of facial paralysis. (20048607)
2010
15
Bilateral horizontal gaze palsy with unilateral peripheral facial paralysis caused by pontine tegmentum infarction. (19426898)
2009
16
Dual innervation method using one-stage reconstruction with free latissimus dorsi muscle transfer for re-animation of established facial paralysis: simultaneous reinnervation of the ipsilateral masseter motor nerve and the contralateral facial nerve to improve the quality of smile and emotional facial expressions. (19010754)
2009
17
"Babysitter" procedure with concomitant muscle transfer in facial paralysis. (19935298)
2009
18
Facial paralysis. Preface. (18470825)
2008
19
Assessing impairment and disability of facial paralysis in patients with vestibular schwannoma. (17224525)
2007
20
A method of selecting acupoints for acupuncture treatment of peripheral facial paralysis by thermography. (18186583)
2007
21
Facial nerve paralysis: a complication of distraction osteogenesis of the mandibular ramus in the treatment of temporomandibular joint ankylosis. (17667675)
2007
22
Agreement between clinical and electromyographic assessments during the course of peripheric facial paralysis. (17613575)
2007
23
Correction of ectropion in facial paralysis. (16582815)
2006
24
Correction of ectropion in facial paralysis. (16582814)
2006
25
Idiopathic facial paralysis (Bell's palsy) in the immediate puerperium in a patient with mild preeclampsia: a case report. (15868184)
2005
26
Facial paralysis in a patient with cholesterol cyst of the petrous bone. (16213957)
2005
27
Contralateral botulinum injections improve drinking ability and facial symmetry in patients with facial paralysis. (15767069)
2005
28
The role of the middle fossa approach in the management of traumatic facial paralysis. (15724737)
2004
29
Delayed facial paralysis after vestibular schwannoma surgery: role of herpes viruses reactivation--our experience in eight cases. (15354015)
2004
30
Neurovascular free-muscle transfer for the treatment of established facial paralysis following ablative surgery in the parotid region. (15114115)
2004
31
Bilateral simultaneous facial paralysis--differential diagnosis and treatment options. A case report and review of literature. (12836471)
2003
32
Prospective evaluation of eyelid function with gold weight implant and lower eyelid shortening for facial paralysis. (11843684)
2002
33
Idiopathic facial paralysis (Bell's palsy). (12170171)
2002
34
Impact of facial paralysis on patients with acoustic neuroma. (10983957)
2000
35
Facial paralysis secondary to acute otitis media. (11063365)
2000
36
Antinuclear antibody negative systemic lupus erythematosus presenting as bilateral facial paralysis. (9558189)
1998
37
Electromyographic analysis of profound facial nerve paralysis following acoustic neuroma resection. (9186971)
1997
38
Validation of objective measures for facial paralysis. (9331311)
1997
39
Quantitative analysis of facial motion components: anatomic and nonanatomic motion in normal persons and in patients with complete facial paralysis. (9180713)
1997
40
Muscle transplantation for reconstruction of a smile after facial paralysis past, present, and future. (9379888)
1996
41
One-stage microneurovascular free abductor hallucis muscle transplantation for reanimation of facial paralysis. (7604134)
1995
42
Facial paralysis in children. (8572104)
1994
43
Long-term results of severe facial paralysis. (10774436)
1994
44
Occult parotid malignancy discovered 10 years after acute onset of complete facial paralysis. (8108160)
1994
45
The role of physical therapy in patients with facial paralysis: state of the art. (10774330)
1994
46
Bilateral facial paralysis related to sexually transmitted herpes simplex: clinical course and MRI findings. (8464645)
1993
47
Gore-Tex implants: applications in facial paralysis rehabilitation and soft-tissue augmentation. (1405972)
1992
48
Management of facial paralysis due to temporal bone fracture. (18748274)
1978
49
Vestibular disease, and its relationship to facial paralysis in the horse: a clinical study of 7 cases. (306818)
1977
50
Bilateral facial paralysis and abducens palsy; two cases. (18225098)
1948

Genetic Variations for Facial Paralysis

Expression for genes affiliated with Facial Paralysis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Facial Paralysis

Search GEO for disease gene expression data for Facial Paralysis.

Pathways for genes affiliated with Facial Paralysis

Compounds for genes affiliated with Facial Paralysis

Sources:
45Novoseek, 60Tocris Bioscience
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Compounds related to Facial Paralysis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1cytochalasin d45 6010.7TGFB1, GSN, NF2
2digitonin459.3GSN, CD82
3paraffin459.0TGFB1, TP63, CD82, NF2

GO Terms for genes affiliated with Facial Paralysis

Sources:
16Gene Ontology
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Biological processes related to Facial Paralysis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lens fiber cell differentiationGO:07030610.0TGFB1, NF2
2negative regulation of DNA replicationGO:00815610.0TGFB1, NF2
3negative regulation of cell-cell adhesionGO:0224089.9TGFB1, NF2
4cell-cell junction organizationGO:0452169.8TGFB1, NF2, CADM1
5positive regulation of transcription from RNA polymerase II promoterGO:0459448.8HOXB1, LRP5, TP63, GSX1, TGFB1

Products for genes affiliated with Facial Paralysis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Facial Paralysis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet