MCID: FCL012
MIFTS: 49

Facial Paralysis malady

Summaries for Facial Paralysis

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Facial nerve paralysis is a common problem that involves the paralysis of any structures innervated by... more...

MalaCards: Facial Paralysis, also known as facial palsy, is related to acoustic neuroma and sost-related sclerosing bone dysplasia. An important gene associated with Facial Paralysis is HOXB1 (homeobox B1). The drugs scopolamine and scopolamine hydrobromide and the compounds cytochalasin d and digitonin have been mentioned in the context of this disorder. Affiliated tissues include bone, eye and skin, and related mouse phenotypes are respiratory system and skeleton.

Aliases & Classifications for Facial Paralysis

About this section
Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt
See all sources

Aliases & Descriptions:

facial paralysis 8 10 60
facial palsy 8


External Ids:

Disease Ontology8 DOID:13934
MeSH34 D005158
NCIt39 C26769

Related Diseases for Facial Paralysis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Facial Paralysis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 186)
idRelated DiseaseScoreTop Affiliating Genes
1acoustic neuroma30.3FKBP4
2sost-related sclerosing bone dysplasia30.1LRP5, TGFB1
3neurofibromatosis30.1CADM1, NF2
4camurati-engelmann disease29.9TGFB1, LRP5
5breast cancer29.9TP63, NF2, FKBP4, GSN, TGFB1
6squamous cell carcinoma29.9GSN, CADM1, TP63, TGFB1, CD82
7bell's palsy10.7
8otitis media10.5
9bone fracture10.4
10ectropion10.3
11wegener's granulomatosis10.3
12parotitis10.3
13herpes simplex10.3
14melkersson-rosenthal syndrome10.3
15cholesteatoma10.3
16hypertension10.3
17neuroma10.3
18familial recurrent peripheral facial palsy10.2
19deafness - ear malformation - facial palsy10.2
20meningitis10.2
21hereditary congenital facial paresis 310.2
22isolated hereditary congenital facial paralysis10.2
23tolosa-hunt syndrome10.2
24anotia facial palsy cardiac defect10.2
25deafness conductive stapedial ear malformation facial palsy10.2
26recurrent peripheral facial palsy10.2
27middle ear adenoma10.1
28petrositis10.1
29adenoma10.1
30amyloidosis10.1
31glomus tumor10.1
32lagophthalmos10.1
33neuritis10.1
34neuroblastoma10.1
35skull base neoplasm10.1
36suppurative otitis media10.1
37tuberculosis10.1
38moebius syndrome10.1
39familial amyloidosis, finnish type10.1
40cat-scratch disease10.1
41cerebritis10.1
42leptospirosis10.1
43urofacial syndrome10.1
44cutaneous anthrax10.1
45chickenpox10.1
46adult syndrome10.1
47craniometaphyseal dysplasia10.1
48mumps10.1
49cerebral palsy10.1
50encephalitis10.1

Graphical network of the top 20 diseases related to Facial Paralysis:



Diseases related to facial paralysis

Clinical Features for Facial Paralysis

About this section

Drugs & Therapeutics for Facial Paralysis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Facial Paralysis

Drug clinical trials:

Search ClinicalTrials for Facial Paralysis

Search NIH Clinical Center for Facial Paralysis

Search CenterWatch for Facial Paralysis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Facial Paralysis

About this section

Anatomical Context for Facial Paralysis

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Facial Paralysis:

32
Bone, Eye, Skin, Testes, Heart, Breast, Liver, Cortex, Brain, Tongue

Animal Models for Facial Paralysis or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Facial Paralysis:

36 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.7ANKH, NF2, HOXB1, SP6, TP63, GSN
2MP:00053908.6CADM1, ANKH, NF2, HOXB1, LRP5, TP63
3MP:00053828.5ANKH, NF2, HOXB1, LRP5, SP6, TP63
4MP:00053978.3CADM1, PRF1, ANKH, HOXB1, LRP5, GSX1
5MP:00107718.3PRF1, NF2, FKBP4, HOXB1, SP6, TP63
6MP:00053898.2CADM1, PRF1, ANKH, NF2, FKBP4, TP63
7MP:00053868.1PRF1, ANKH, NF2, HOXB1, LRP5, TP63
8MP:00053878.1NF2, ANKH, PRF1, CADM1, HOXB1, LRP5
9MP:00053767.8PRF1, ANKH, NF2, FKBP4, LRP5, TP63
10MP:00053797.7TGFB1, CADM1, PRF1, NF2, FKBP4, HOXB1
11MP:00053787.6CADM1, PRF1, ANKH, NF2, FKBP4, HOXB1
12MP:00107687.4PRF1, ANKH, NF2, FKBP4, HOXB1, LRP5

Publications for Facial Paralysis

About this section
Sources:
50PubMed
See all sources

Articles related to Facial Paralysis:

(show top 50)    (show all 561)
idTitleAuthorsYear
1
Fifteen-year survey of one-stage latissimus dorsi muscle transfer for treatment of longstanding facial paralysis. (22960057)
2013
2
Robot Assisted Physiotherapy to Support Rehabilitation of Facial Paralysis. (24122562)
2013
3
Hemihypoglossal nerve transfer for acute facial paralysis. (23101452)
2013
4
Facial nerve paralysis due to intra-aural Hyalomma tick infestation. (23339950)
2012
5
Huge middle ear adenoma with delayed facial nerve paralysis. (22711394)
2012
6
Acute motor-sensory axonal Guillain-BarrAc syndrome with unilateral facial nerve paralysis after rotavirus gastroenteritis in a 2-year-old boy. (21915637)
2012
7
Dynamic facial prosthetics for sufferers of facial paralysis. (23386867)
2011
8
Surgical treatment of the periocular complex and improvement of quality of life in patients with facial paralysis. (21422446)
2011
9
Razi's description and treatment of facial paralysis. (21194269)
2011
10
Sir Charles Bell was not affected by facial paralysis himself! (20464311)
2010
11
Features of facial asymmetry following incomplete recovery from facial paralysis. (20879064)
2010
12
Management and outcomes of facial paralysis from intratemporal blunt trauma: a systematic review. (20564723)
2010
13
Facial paralysis rehabilitation: state of the art. (20625293)
2010
14
Clinical and electromyographic study of lateral preference in mastication in patients with longstanding peripheral facial paralysis. (20572435)
2009
15
Outcome of patients presenting with idiopathic facial nerve paralysis (Bell's palsy) in a tertiary centre--a five year experience. (20058577)
2009
16
WITHDRAWN: Corticosteroids for Bell's palsy (idiopathic facial paralysis). (19370572)
2009
17
Objective grading of facial paralysis using Local Binary Patterns in video processing. (19163791)
2008
18
Restoration of eyelid closure in facial paralysis using artificial muscle: preliminary cadaveric analysis. (17828051)
2007
19
Facial paralysis associated with glomus jugulare tumors. (17195751)
2007
20
Facial paralysis. (16628742)
2006
21
Objective facial paralysis grading based on Pface and eigenflow. (15503959)
2004
22
Problems with eating and drinking in patients with unilateral peripheral facial paralysis. (14571331)
2003
23
Positive effects of mime therapy on sequelae of facial paralysis: stiffness, lip mobility, and social and physical aspects of facial disability. (12851564)
2003
24
Minimally invasive brow suspension for facial paralysis. (12633208)
2003
25
Cyclosporine-associated facial paralysis in a child with renal transplant. (12172772)
2002
26
Facial paralysis in Wegener's granulomatosis of the middle ear. (11276335)
2001
27
Aciclovir for Bell's palsy (idiopathic facial paralysis). (11406014)
2001
28
The effect of muscle transplantation after unilateral partial facial paralysis on craniofacial growth and development: relationship between muscle and nerve histomorphometric findings. (10626980)
2000
29
Magnetic resonance imaging findings in a patient with bilateral facial paralysis due to malignant lymphoma. (10897402)
2000
30
Revascularized muscle transfer for facial reanimation after long-standing facial paralysis. (11030393)
2000
31
Partial facial paralysis following temporal artery biopsy. (11584863)
2000
32
Seasonal patterns of idiopathic facial paralysis: a 16-year study. (9949364)
1999
33
Effect of nerve repair after unilateral partial facial paralysis on craniofacial growth and development. (10654688)
1999
34
The effect of unilateral partial facial paralysis and muscle ablation on craniofacial growth and development: an experimental study in the rabbit. (9810984)
1998
35
Boy with fatigue and facial paralysis. (9832737)
1998
36
Electromyographic examination of patients with unilateral cortical facial paralysis. (9419123)
1997
37
Neuromuscular retraining for facial paralysis. (9295250)
1997
38
Acute otitis media and facial paralysis in children. (8546426)
1996
39
Facial paralysis and inflammatory pseudotumor of the facial nerve in a child. (7501405)
1995
40
Facial paralysis at birth: medicolegal and clinical implications. (8572130)
1995
41
Rehabilitation of long-term facial paralysis. (7644845)
1995
42
Long-term effects of neuromuscular rehabilitation of chronic facial paralysis. (8551533)
1995
43
An investigation of acute facial paralysis in animals induced by exposure of the tympanic membrane to cold air. (7501389)
1995
44
Free rectus femoris muscle transfer for one-stage reconstruction of established facial paralysis. (8047592)
1994
45
Temporal bone fracture, facial paralysis, only hearing ear: management. (8572101)
1994
46
MAcniA"re's attacks associated with facial paralysis. (8217743)
1993
47
Epiphora in facial paralysis. (8461903)
1993
48
Comments regarding prognostic significance of stapes reflex in Bell's palsy, application of electroneuronography in managing Bell's palsy, and tuberculosis of the middle ear in facial paralysis, management of an injured facial nerve following middle ear surgery. (1805644)
1991
49
Dressler's syndrome and facial paralysis. (1994307)
1991
50
Trigeminal zoster producing facial paralysis and postural hypotension. (174771)
1976

Genetic Variations for Facial Paralysis

About this section

Expression for genes affiliated with Facial Paralysis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Facial Paralysis

Search GEO for disease gene expression data for Facial Paralysis.

Pathways for genes affiliated with Facial Paralysis

About this section

Compounds for genes affiliated with Facial Paralysis

About this section
Sources:
44Novoseek, 59Tocris Bioscience
See all sources

Compounds related to Facial Paralysis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1cytochalasin d44 5910.7TGFB1, GSN, NF2
2digitonin449.3GSN, CD82
3paraffin449.0TGFB1, TP63, CD82, NF2

GO Terms for genes affiliated with Facial Paralysis

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Facial Paralysis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lens fiber cell differentiationGO:07030610.0TGFB1, NF2
2negative regulation of DNA replicationGO:00815610.0TGFB1, NF2
3negative regulation of cell-cell adhesionGO:0224089.9TGFB1, NF2
4cell-cell junction organizationGO:0452169.8TGFB1, NF2, CADM1
5positive regulation of transcription from RNA polymerase II promoterGO:0459448.8HOXB1, LRP5, TP63, GSX1, TGFB1

Products for genes affiliated with Facial Paralysis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Facial Paralysis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet