MCID: FCT013
MIFTS: 15

Factor V Leiden Thrombophilia

Categories: Rare diseases, Blood diseases

Aliases & Classifications for Factor V Leiden Thrombophilia

MalaCards integrated aliases for Factor V Leiden Thrombophilia:

Name: Factor V Leiden Thrombophilia 72 23 49 24
Hereditary Resistance to Activated Protein C 23 49 24
Apc Resistance, Leiden Type 49 24
Thrombophilia Due to Activated Protein C Resistance 69

Characteristics:

GeneReviews:

23
Penetrance See clinical description...

Classifications:



External Ids:

UMLS 69 C1861171

Summaries for Factor V Leiden Thrombophilia

NIH Rare Diseases : 49 Factor V Leiden thrombophilia is a genetic disorder that makes it more likely for you to develop a blood clot sometime during your life. Still, it is estimated that 95% of people with factor V Leiden never develop a clot. When a clot does form, the clot most often occurs in your leg (deep venous thrombosis or DVT) or lungs (pulmonary embolism or PE). Factor V Leiden is the name of a specific genemutation in the F5 gene. This gene plays a role in how your body forms blood clots after an injury. People can inherit one or two copies of the factor V Leiden gene mutation. Last updated: 8/23/2017

MalaCards based summary : Factor V Leiden Thrombophilia, also known as hereditary resistance to activated protein c, is related to thrombophilia due to activated protein c resistance and thrombophilia. Affiliated tissues include lung.

Genetics Home Reference : 24 Factor V Leiden thrombophilia is an inherited disorder of blood clotting. Factor V Leiden is the name of a specific gene mutation that results in thrombophilia, which is an increased tendency to form abnormal blood clots that can block blood vessels.

GeneReviews: NBK1368

Related Diseases for Factor V Leiden Thrombophilia

Diseases related to Factor V Leiden Thrombophilia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 thrombophilia due to activated protein c resistance 11.6
2 thrombophilia 10.3
3 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 10.0
4 thrombosis 10.0
5 legg-calve-perthes disease 9.9
6 kienbock's disease 9.9
7 thrombophilia due to thrombin defect 9.8
8 cerebritis 9.8

Graphical network of the top 20 diseases related to Factor V Leiden Thrombophilia:



Diseases related to Factor V Leiden Thrombophilia

Symptoms & Phenotypes for Factor V Leiden Thrombophilia

Drugs & Therapeutics for Factor V Leiden Thrombophilia

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Assessment of the Prevalence of Major Psychiatric Disorders in a Cohort of Women With Clinical Criteria Corresponding to Pure, Abortive-form, Obstetrical, Antiphospholipid Syndrome Completed NCT02833194

Search NIH Clinical Center for Factor V Leiden Thrombophilia

Genetic Tests for Factor V Leiden Thrombophilia

Anatomical Context for Factor V Leiden Thrombophilia

MalaCards organs/tissues related to Factor V Leiden Thrombophilia:

38
Lung

Publications for Factor V Leiden Thrombophilia

Articles related to Factor V Leiden Thrombophilia:

# Title Authors Year
1
Bilateral Legg-Calve-Perthes Disease and Kienbock's Disease in a Child With Factor V Leiden Thrombophilia: A Case Report. ( 27698645 )
2016
2
Factor V leiden thrombophilia in a female collegiate soccer athlete: a case report. ( 23675803 )
2013
3
Factor V Leiden thrombophilia. ( 21116184 )
2011
4
Factor V Leiden thrombophilia: presentation of three patients and a literature review. ( 19610561 )
2006
5
Factor V Leiden Thrombophilia ( 20301542 )
1993

Variations for Factor V Leiden Thrombophilia

Expression for Factor V Leiden Thrombophilia

Search GEO for disease gene expression data for Factor V Leiden Thrombophilia.

Pathways for Factor V Leiden Thrombophilia

GO Terms for Factor V Leiden Thrombophilia

Sources for Factor V Leiden Thrombophilia

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