MCID: FCT013
MIFTS: 34

Factor V Leiden Thrombophilia malady

Genetic diseases, Rare diseases, Blood diseases categories
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Summaries for Factor V Leiden Thrombophilia

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NIH Rare Diseases:42 Factor v leiden thrombophilia is an inherited disorder that results in an increased risk of developing abnormal blood clots. factor v leiden is the name of a specific gene mutation in the f5 gene. this gene plays a critical role in the normal formation of blood clots in response to an injury. people can inherit one or two copies of the factor v leiden gene mutation. those who inherit one copy are called heterozygotes. people who inherit two copies of the mutation, one from each parent, are called homozygotes. having the factor v leiden mutation increases your risk for developing a clot in your legs called a deep venous thrombosis (dvt). it also increases your risk of developing a clot that travels through the bloodstream and lodges in the lungs, called a pulmonary embolism (pe). last updated: 6/29/2012

MalaCards based summary: Factor V Leiden Thrombophilia, also known as hereditary resistance to activated protein c, is related to thromboembolism and venous thromboembolism. An important gene associated with Factor V Leiden Thrombophilia is F5 (coagulation factor V (proaccelerin, labile factor)). The drugs tranexamic acid and tranexamic acid pwdr have been mentioned in the context of this disorder. Affiliated tissues include brain, lung and skin.

MedlinePlus:33 Bleeding is the loss of blood. it can happen inside or outside the body. bleeding can be a reaction to a cut or other wound. it can also result from an injury to internal organs. there are many situations in which you might bleed. a bruise is bleeding under the skin. some strokes are caused by bleeding in the brain. other bleeding, such as gastrointestinal bleeding, coughing up blood, or vaginal bleeding, can be a symptom of a disease. normally, when you bleed, your blood forms clots to stop the bleeding. severe bleeding may require first aid or a trip to the emergency room. if you have a bleeding disorder, your blood does not form clots normally.

Genetics Home Reference:21 Factor V Leiden thrombophilia is an inherited disorder of blood clotting. Factor V Leiden is the name of a specific gene mutation that results in thrombophilia, which is an increased tendency to form abnormal blood clots that can block blood vessels.

GeneReviews summary for factor-v-leiden

Aliases & Classifications for Factor V Leiden Thrombophilia

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Factor V Leiden Thrombophilia, Aliases & Descriptions:

Name: Factor V Leiden Thrombophilia 65 19 42 20 21 62
Hereditary Resistance to Activated Protein C 65 19 42 21 62
Apc Resistance, Leiden Type 65 42 21
Bleeding Disorders 65 33 62
Factor V Leiden Mutation 19 62
 
Bleeding 44 33
Thrombophilia Due to Deficiency of Cofactor for Activated Protein C, Leiden Type 65
Activated Protein C Resistance 62
Hemorrhage 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Blood diseases


Related Diseases for Factor V Leiden Thrombophilia

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Graphical network of the top 20 diseases related to Factor V Leiden Thrombophilia:



Diseases related to factor v leiden thrombophilia

Symptoms for Factor V Leiden Thrombophilia

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Drugs & Therapeutics for Factor V Leiden Thrombophilia

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Drug clinical trials:

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Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Factor V Leiden Thrombophilia

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Genetic tests related to Factor V Leiden Thrombophilia:

id Genetic test Affiliating Genes
1 Factor V Leiden Thrombophilia20 F5

Anatomical Context for Factor V Leiden Thrombophilia

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MalaCards organs/tissues related to Factor V Leiden Thrombophilia:

32
Brain, Lung, Skin

Animal Models for Factor V Leiden Thrombophilia or affiliated genes

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Publications for Factor V Leiden Thrombophilia

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Articles related to Factor V Leiden Thrombophilia:

idTitleAuthorsYear
1
Factor V leiden thrombophilia in a female collegiate soccer athlete: a case report. (23675803)
2013
2
Factor V Leiden thrombophilia. (21116184)
2011
3
Factor V Leiden thrombophilia: presentation of three patients and a literature review. (19610561)
2006
4
Factor V Leiden Thrombophilia (20301542)
1993

Variations for Factor V Leiden Thrombophilia

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Expression for genes affiliated with Factor V Leiden Thrombophilia

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Expression patterns in normal tissues for genes affiliated with Factor V Leiden Thrombophilia

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Pathways for genes affiliated with Factor V Leiden Thrombophilia

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Compounds for genes affiliated with Factor V Leiden Thrombophilia

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GO Terms for genes affiliated with Factor V Leiden Thrombophilia

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Products for genes affiliated with Factor V Leiden Thrombophilia

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  • Antibodies
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Sources for Factor V Leiden Thrombophilia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet