MCID: FCT013
MIFTS: 26

Factor V Leiden Thrombophilia malady

Categories: Genetic diseases, Rare diseases, Blood diseases

Aliases & Classifications for Factor V Leiden Thrombophilia

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Aliases & Descriptions for Factor V Leiden Thrombophilia:

Name: Factor V Leiden Thrombophilia 68 21 45 22 23
Hereditary Resistance to Activated Protein C 68 21 45 22 23
Apc Resistance, Leiden Type 68 45 23
Factor V Leiden Mutation 21 22 65
Bleeding Disorders 68 35
Bleeding 47 35
Thrombophilia Due to Deficiency of Cofactor for Activated Protein C, Leiden Type 68
 
Thrombophilia Due to Activated Protein C Resistance 65
Blood Coagulation Disorders 65
Thrombosis Risk Factor 22
Bleeding Tendency 65
Thrombophilia V 22
Factor V R506q 22
Hemorrhage 65

Classifications:



External Ids:

UMLS65 C1861171, C1458140, C0584960 C0019080, more

Summaries for Factor V Leiden Thrombophilia

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NIH Rare Diseases:45 Factor v leiden thrombophilia is an inherited disorder that results in an increased risk of developing abnormal blood clots. factor v leiden is the name of a specific gene mutation in the f5 gene. this gene plays a critical role in the normal formation of blood clots in response to an injury. people can inherit one or two copies of the factor v leiden gene mutation. those who inherit one copy are called heterozygotes. people who inherit two copies of the mutation, one from each parent, are called homozygotes. having the factor v leiden mutation increases your risk for developing a clot in your legs called a deep venous thrombosis (dvt). it also increases your risk of developing a clot that travels through the bloodstream and lodges in the lungs, called a pulmonary embolism (pe). last updated: 6/29/2012

MalaCards based summary: Factor V Leiden Thrombophilia, also known as hereditary resistance to activated protein c, is related to bleeding disorder, platelet-type, 16, autosomal dominant and bernard-soulier syndrome, type c. An important gene associated with Factor V Leiden Thrombophilia is F5 (Coagulation Factor V), and among its related pathways are GP1b-IX-V activation signalling and Gamma carboxylation, hypusine formation and arylsulfatase activation. The drugs tranexamic acid and tranexamic acid pwdr have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and brain, and related mouse phenotypes are cardiovascular system and immune system.

Genetics Home Reference:23 Factor V Leiden thrombophilia is an inherited disorder of blood clotting. Factor V Leiden is the name of a specific gene mutation that results in thrombophilia, which is an increased tendency to form abnormal blood clots that can block blood vessels.

MedlinePlus:35 Bleeding is the loss of blood. it can happen inside or outside the body. bleeding can be a reaction to a cut or other wound. it can also result from an injury to internal organs. there are many situations in which you might bleed. a bruise is bleeding under the skin. some strokes are caused by bleeding in the brain. other bleeding, such as gastrointestinal bleeding, coughing up blood, or vaginal bleeding, can be a symptom of a disease. normally, when you bleed, your blood forms clots to stop the bleeding. severe bleeding may require first aid or a trip to the emergency room. if you have a bleeding disorder, your blood does not form clots normally.

GeneReviews summary for NBK1368

Related Diseases for Factor V Leiden Thrombophilia

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Diseases related to Factor V Leiden Thrombophilia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 281)
idRelated DiseaseScoreTop Affiliating Genes
1bleeding disorder, platelet-type, 16, autosomal dominant33.7F2, F3, F5, GP1BA, VWF
2bernard-soulier syndrome, type c32.7F2, GP1BA, VWF
3thrombophilia due to activated protein c resistance31.0F10, F2, F3, F5, F8, F9
4von willibrand disease, type 330.2F2, F3, F8, VWF
5panic disorder30.1F5, F8, SERPINC1
6factor x deficiency30.1F10, F2, F3, F5, F9
7acquired hemophilia a30.1F10, F5, F8, F9
8oral squamous cell carcinoma30.0F2, F5, GP1BA
9thyroid cancer29.7F3, F5, PLAT, VWF
10factor v deficiency29.6F10, F2, F3, F5, F9, VWF
11adenocarcinoma29.1F10, F2, F3, F5, PLAT, SERPINC1
12myocardial infarction26.4F10, F11, F2, F3, F5, F8
13bleeding disorder, platelet-type, 812.7
14bleeding disorder, platelet-type, 1312.6
15bleeding disorder, platelet-type, 1112.6
16bleeding disorder, platelet-type, 1512.6
17bleeding disorder, platelet-type, 1812.6
18bleeding disorder, platelet-type, 1712.5
19bleeding disorder, platelet-type, 1912.5
20bleeding disorder, east texas type12.4
21thrombomodulin-related bleeding disorder12.4
22bleeding disorder due to caldag-gefi deficiency12.4
23gray platelet syndrome11.9
24quebec platelet disorder11.8
25scott syndrome11.8
26glanzmann thrombasthenia11.6
27von willebrand disease, platelet-type11.6
28platelet glycoprotein iv deficiency11.3
29may-hegglin anomaly11.3
30glycoprotein ia deficiency11.3
31primary release disorder of platelets11.3
32prothrombin-related thrombophilia10.8
33benign epilepsy with centrotemporal spikes10.5F3, F5
34tall stature-scoliosis-macrodactyly of the great toes syndrome10.5F2, F5
35central nervous system osteosarcoma10.5F2, F3
36liver failure acute infantile10.5F2, F5
37sugarman brachydactyly10.5F2, F5
38epiglottitis10.5F2, F3
39internuclear ophthalmoplegia10.5F2, F5
40microscopic colitis10.5F2, F5
41vaginal villous adenoma10.5F2, F3
42catatrichy10.5F3, F5
43crohn's disease10.5F5, VWF
44type 2n von willebrand disease10.5F8, VWF
45factor v and factor viii, combined deficiency of10.5F5, F8
46tyrobp-related polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy10.5F8, VWF
47herpes gestationis10.5F2, F3
48hypertrichosis10.4F2, F3
49microcytic anemia10.4F2, F3
50splenic abscess10.4F2, F3

Graphical network of the top 20 diseases related to Factor V Leiden Thrombophilia:



Diseases related to factor v leiden thrombophilia

Symptoms for Factor V Leiden Thrombophilia

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Drugs & Therapeutics for Factor V Leiden Thrombophilia

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Drugs for Factor V Leiden Thrombophilia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Heparinapproved, investigationalPhase 4, Phase 37199005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
2
DalteparinapprovedPhase 4, Phase 32819041-08-1
Synonyms:
Daltepariininatrium
Dalteparin Sodyum
Dalteparin sodium
Dalteparin sodná sůl
Dalteparin-nátrium
Dalteparina sódica
 
Dalteparinnatrium
Dalteparino natrio druska
Dalteparinum Natricum
Dalteparyna sodowa
Daltéparine sodique
Fragmin
Heparin Fragment KABI 2165
Tedelparin
3calcium heparinPhase 4, Phase 3719
4ThrombinPhase 4269
5Heparin, Low-Molecular-WeightPhase 4, Phase 3286
6Fibrinolytic AgentsPhase 41567
7AnticoagulantsPhase 41760
8
AspirinapprovedPhase 3102950-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
7 Select Adult Chewable Aspirin
7 Select Aspirin
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Adult Chewable Low Dose Aspirin
Adult Low Dose Aspirin
Adult Low Dose Aspirin Enteric Safety Coated
Adult Low Dose Enteric Coated Aspirin
Adult Low Strength Aspirin
Aloxiprimum
Asacard
Asagran
Asaphen
Asatard
Ascoden-30
Ascriptin Maximum Strength Buffered Aspirin
Ascriptin Regular Strength Buffered Aspirin
Aspalon
Aspec
Aspergum
Aspi-cor
Aspir Low
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin 81 Mg
Aspirin 81 Mg Low Dose
Aspirin Adult Low Dose
Aspirin Adult Low Strength
Aspirin Adult Low Strength Aspirin
Aspirin Adult low strength
Aspirin Chewable Low Dose
Aspirin Delayed Release
Aspirin EC
Aspirin EXTRA STRENGTH
Aspirin Ec
Aspirin Enteric
Aspirin Enteric Coated
Aspirin Enteric Coated Low Dose
Aspirin Enteric Safety Coated
Aspirin Enteric Safety-Coated
Aspirin Low Dose
Aspirin Low Dose Chewable
Aspirin Low Dose Enteric Coated
Aspirin Low Dose Safety Coated
Aspirin Low Strength
Aspirin Nsaid
Aspirin Regular Strength
Aspirin Regular Strength regular strength
Aspirin Regular strength
Aspirin Safety Coated
Aspirin Safety Coated Adult Low Dose
Aspirin Safety coated
Aspirin Thin coated
Aspirin [BAN:JAN]
Aspirin adult low dose
Aspirin adult low strength
Aspirin enteric safety coated
Aspirin low dose
Aspirin low dose chewable
Aspirin low dose enteric coated
Aspirin regular strength
Aspirina 03
Aspirine
Aspiring
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Advanced Aspirin Extra Strength
Bayer Advanced Aspirin Regular Strength
Bayer Aspirin 8 Hour
Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange
Bayer Aspirin Regimen Regular Strength
Bayer Buffered
Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavored
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Fast Release
Bayer Genuine Aspirin
Bayer Low Dose
Bayer Plus
Bayer Plus Extra Strength
Bayer Womens
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Buffered Aspirin
Bufferin
Bufferin LOW DOSE BUFFERED ASPIRIN
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Care One Aspirin
Cemirit
Chewable Adult Low Dose Aspirin
Chewable Aspirin
Chewable Low Dose Aspirin
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Critical Care Aspirin To Go
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dg Health Aspirin
Direct Safety Aspirin
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ec-81aspirin Enteric Coated
Ecolen
Ecotrin
Ecotrin Regular Strength
Empirin
Empirin with Codeine
Endosprin
Endydol
Enteric Aspirin
Enteric Coated Aspirin
Enteric Coated Aspirin Regular Strength
Enteric Coated Aspirin Regular strength
Enteric Coated Aspirin regular strength
Enteric Coated Asprin 81 Mg
Enteric Coated Low Dose Aspirin
 
Enteric Safety Coated Aspirin
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Equaline Aspirin
Equaline Aspirin adult low dose
Equate Aspirin
Equate Aspirin chewable
Extren
Fasprin
Flanax Aspirin Pain Reliever
Formucare Aspirin
Genuine Aspirin
Globentyl
Globoid
Good Neighbor Pharmacy Aspirin
Good Neighbor Pharmacy Aspirin Enteric Safety Coated
Good Neighbor Pharmacy Aspirin orange flavor chewable
Good Sense Aspirin
Good Sense Aspirin Enteric Safety Coated
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Handy Solutions Genuine Aspirin Bayer
Health Mart Aspirin
Health Mart Regular Strength Enteric Coated Aspirin
Health Sense Adult Chewable Low Strength Aspirin
Health Sense Aspirin 81
Health Sense Ecpirin
Healthy Accents Aspirin
Helicon
Henry Schein Aspirin
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kroger Value Aspirin
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Leader Aspirin
Leader Cardinal Health Aspirin
Leader Low Dose Aspirin
Levius
Lopac-A-5376
Lopac0_000038
Low Dose Adult Aspirin
Low Dose Aspirin
Low Dose Aspirin 81 Mg Safety Coated
Low Dose Aspirin Enteric Safety Coated
Low Dose Asprin
Low Dose Chewable Aspirin
Low Dose Miniprin Enteric Safety Coated
Low Dose Pain Relief Aspirin
Low Strength Chewable Aspirin
Low-dose Aspirin
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medi First Plus Aspirin
Medi-first Aspirin
Medique Aspirin
Medisyl
Micristin
Micro-coated Aspirin
Miniprin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
North Aspirin
Novasen
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Pain Relief Aspirin
Pain Relief Aspirin Low Dose
Persistin
Pharbest Aspirin 325mg
Pharbest Regular Strength Aspirin
Pharmacin
Pirseal
Plus Pharma NSAID 325 mg
Plus Pharma Nsaid Aspirin
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rapid Comfort Aspirin
Regular Strength Aspirin
Regular Strength Aspirin Ec
Regular Strength Buffered Aspirin
Regular Strength Enteric Aspirin
Regular Strength Enteric Coated Aspirin
Regular Strength Pain Relief
Regular Strength Tri-buffered Aspirin
Rexall Aspirin
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
Rugby Aspirin
Rx Act Aspirin
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Safety Coated Aspirin
Safety Coated Enteric Aspirin
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Smart Health Aspirin regular strength
Smart Sense Aspirin
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Solves - Aspirin Cherry
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
St. Joseph Chewable Aspirin
St. Joseph Safety Coated Aspirin
Sunmark Aspirin
Sunmark Aspirin Regular Strength
Sunmark Aspirin adult low strength
Sunmark Aspirin low dose
Supac
Tasprin
Temperal
Toldex
Topcare Aspirin
Tri-buffered Aspirin
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Uncoated Aspirin
Value Pharma Aspirin Pain Reliever
Value Pharmapain Reliever Extra Strength
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
Zee Aspirin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
9Cyclooxygenase InhibitorsPhase 32225
10Peripheral Nervous System AgentsPhase 318510
11Pharmaceutical SolutionsPhase 37004
12AnalgesicsPhase 39358
13Acetylsalicylic acid lysinatePhase 39
14Platelet Aggregation InhibitorsPhase 31935
15Analgesics, Non-NarcoticPhase 35184
16Anti-Inflammatory AgentsPhase 38478
17Anti-Inflammatory Agents, Non-SteroidalPhase 33549
18Antirheumatic AgentsPhase 38496
19Estrogens2144
20Immunologic Factors18483
21Protein C86
22Immunoglobulins4477
23protein S12
24Antibodies, Antiphospholipid25
25Antibodies4477
26Antithrombin III563
27Antithrombins574
28Factor VIII272

Interventional clinical trials:

(show all 12)
idNameStatusNCT IDPhase
1Low Molecular Weight Heparin in Prevention of Recurrent Arteriovenous Graft Thrombosis in Chronic Hemodialysis Patients.RecruitingNCT01970280Phase 4
2LMWH to Prevent Preeclampsia and Fetal Growth RestrictionTerminatedNCT00260520Phase 4
3Prevention of Maternal and Perinatal Complications by Enoxaparin in Women With Previous Severe PreeclampsiaCompletedNCT00986765Phase 3
4Prevention of Unexplained Recurrent Abortion by EnoxaparineTerminatedNCT00740545Phase 3
5Determination of Performance Characteristics of the MassPLEX Factor II/V Leiden TestCompletedNCT01835483
6Factor V Leiden Mutation and Implantation FailureCompletedNCT00194350
7Effect of DT56a (Femarelle) on the Coagulation System in the Treatment of Postmenopausal WomenCompletedNCT00883272
8Study of Abnormal Blood Clotting in Children With StrokeCompletedNCT00001927
9Thrombophilic Risk Factors in Pediatric Patients Diagnosed at the Ha'Emek Medical CenterCompletedNCT00736008
10Study on Antithrombotic Prevention in Thrombophilia and Pregnancy LossRecruitingNCT02385461
11Thrombophilic Risk Factors in Preterm and Infants Treated at Ha'Emek Medical Center Between the Years 1990 to 2010RecruitingNCT01443273
12Comparative Prevalence of Psychiatric Manifestations in Purely Obstetrical Antiphospholipid SyndromeTerminatedNCT01649479

Search NIH Clinical Center for Factor V Leiden Thrombophilia

Inferred drug relations via UMLS65/NDF-RT43:

Genetic Tests for Factor V Leiden Thrombophilia

About this section

Genetic tests related to Factor V Leiden Thrombophilia:

id Genetic test Affiliating Genes
1 Factor V Leiden Thrombophilia22 F5

Anatomical Context for Factor V Leiden Thrombophilia

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MalaCards organs/tissues related to Factor V Leiden Thrombophilia:

33
Lung, Skin, Brain, Testes, Appendix

Animal Models for Factor V Leiden Thrombophilia or affiliated genes

About this section

MGI Mouse Phenotypes related to Factor V Leiden Thrombophilia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053857.4F10, F11, F2, F3, F5, F9
2MP:00053876.7F11, F2, F3, F8, F9, GP6
3MP:00107686.5F10, F11, F2, F3, F5, F8
4MP:00053976.0F11, F2, F3, F8, F9, GP1BA
5MP:00053764.8F10, F11, F2, F3, F5, F8

Publications for Factor V Leiden Thrombophilia

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Articles related to Factor V Leiden Thrombophilia:

idTitleAuthorsYear
1
Childhood Lichen Planus Pemphigoides: Report of Two Cases Treated Successfully with Systemic Glucocorticoids and Dapsone. (24138413)
2013
2
Genetic susceptibility to renal cell carcinoma: the role of DNA double-strand break repair pathway. (18768505)
2008
3
Bovine achondrogenesis: evidence for defective chondrocyte differentiation. (3606909)
1987
4
Gastric lipoma and mucocele of appendix. Case history. (919997)
1977

Variations for Factor V Leiden Thrombophilia

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Expression for genes affiliated with Factor V Leiden Thrombophilia

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Search GEO for disease gene expression data for Factor V Leiden Thrombophilia.

Pathways for genes affiliated with Factor V Leiden Thrombophilia

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Pathways related to Factor V Leiden Thrombophilia according to GeneCards Suite gene sharing:

(show all 13)
idSuper pathwaysScoreTop Affiliating Genes
19.7GP1BA, VWF
2
Show member pathways
9.5F10, F2, F9
39.5F10, F2, F9
4
Show member pathways
9.4F2, GP1BA, VWF
59.4PLAT, SERPINF2
6
Show member pathways
8.8GP1BA, GP6, VWF
78.8GP1BA, GP6, VWF
88.6F2, GP6, P2RY12, VWF
98.3GP1BA, GP6, P2RY12, VWF
10
Show member pathways
8.0F10, F11, F2, F3, F5, F8
11
Show member pathways
6.6F10, F11, F2, F3, F5, F8
12
Show member pathways
5.3F10, F11, F2, F3, F5, F8
13
Show member pathways
4.7F10, F11, F2, F3, F5, F8

GO Terms for genes affiliated with Factor V Leiden Thrombophilia

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Cellular components related to Factor V Leiden Thrombophilia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:003109310.4F5, VWF
2endoplasmic reticulum lumenGO:00057889.2F10, F5, F8, F9
3extracellular regionGO:00055768.7F11, F5, PLAT, SERPINC1

Biological processes related to Factor V Leiden Thrombophilia according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1COPII vesicle coatingGO:004820810.3F5, F8
2blood coagulation, intrinsic pathwayGO:000759710.2F8, GP1BA
3regulation of blood coagulationGO:003019310.2F2, GP1BA
4positive regulation of collagen biosynthetic processGO:003296710.1F2, SERPINF2
5hemostasisGO:000759910.0GP1BA, P2RY12
6acute-phase responseGO:000695310.0F8, SERPINF2
7signal peptide processingGO:00064659.9F10, F2, F9
8response to woundingGO:00096119.9F2, F3, VWF
9post-translational protein modificationGO:00436879.2F10, F5, F8, F9
10blood coagulationGO:00075967.4F10, F2, F5, F8, F9, GP1BA

Sources for Factor V Leiden Thrombophilia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet