MCID: FCT003
MIFTS: 62

Factor X Deficiency malady

Categories: Genetic diseases, Rare diseases, Blood diseases

Aliases & Classifications for Factor X Deficiency

About this section

Aliases & Descriptions for Factor X Deficiency:

Name: Factor X Deficiency 51 11 47 24 25 69 12 49 38 13 67
Stuart-Prower Factor Deficiency 47 24 25 53 69
F10 Deficiency 47 25 69
Congenital Stuart Factor Deficiency 25 53
Factor 10 Deficiency 69 26
Hereditary Factor X Deficiency Disease 67
 
Stuart Factor Deficiency, Congenital 47
Factor X Deficiency, Congenital 47
Congenital Factor X Deficiency 53
Disease, Stuart-Prower 11
Fa10d 69

Characteristics:

Orphanet epidemiological data:

53
stuart-prower factor deficiency:
Inheritance: Autosomal recessive; Age of onset: All ages; Age of death: any age

HPO:

63
factor x deficiency:
Inheritance: autosomal recessive inheritance
Onset and clinical course: variable expressivity

Classifications:



External Ids:

OMIM51 227600
Disease Ontology11 DOID:2222
MeSH38 D005171
SNOMED-CT61 76642003
Orphanet53 ORPHA328
ICD10 via Orphanet30 D68.2
MedGen36 C0015519

Summaries for Factor X Deficiency

About this section
NIH Rare Diseases:47 Factor X deficiency is a rare condition that affects the blood's ability to clot. The severity of the condition and the associated signs and symptoms can vary significantly from person to person. Common features of factor X deficiency may include easy bruising, frequent nosebleeds, bleeding gums, blood in the urine, and prolonged bleeding after minor injuries. Affected women may also experience heavy menstrual bleeding and may have an increased risk for first trimester miscarriages. Acquired (non-inherited) factor X deficiency, which is the most common form of the condition, generally occurs sporadically in people with no family history of the condition. Acquired factor X deficiency has a variety of causes including liver disease, vitamin K deficiency, exposure to certain medications that affect clotting, and cancers. The inherited form of factor X deficiency (also called congenital factor X deficiency) is caused by changes (mutations) in the F10 gene and is inherited in an autosomal recessive manner. Treatment aims to control bleeding through intravenous (IV) infusions of plasma or concentrates of clotting factors. Last updated: 11/12/2015

MalaCards based summary: Factor X Deficiency, also known as stuart-prower factor deficiency, is related to thrombophilia and thrombophilia due to antithrombin iii deficiency, and has symptoms including menorrhagia, gingival bleeding and epistaxis. An important gene associated with Factor X Deficiency is F10 (Coagulation Factor X), and among its related pathways are Gamma carboxylation, hypusine formation and arylsulfatase activation and Warfarin Pathway, Pharmacodynamics. Affiliated tissues include bone, liver and bone marrow, and related mouse phenotypes are embryo and cardiovascular system.

Genetics Home Reference:25 Factor X deficiency is a rare bleeding disorder that varies in severity among affected individuals. The signs and symptoms of this condition can begin at any age, although the most severe cases are apparent in childhood. Factor X deficiency commonly causes nosebleeds, easy bruising, bleeding under the skin, bleeding of the gums, blood in the urine (hematuria), and prolonged or excessive bleeding following surgery or trauma. Women with factor X deficiency can have heavy or prolonged menstrual bleeding (menorrhagia) or excessive bleeding in childbirth, and may be at increased risk of pregnancy loss (miscarriage). Bleeding into joint spaces (hemarthrosis) occasionally occurs. Severely affected individuals have an increased risk of bleeding inside the skull (intracranial hemorrhage), in the lungs (pulmonary hemorrhage), or in the gastrointestinal tract, which can be life-threatening.

OMIM:51 Factor X deficiency is a rare autosomal recessive bleeding disorder showing variable phenotypic severity. Affected... (227600) more...

UniProtKB/Swiss-Prot:69 Factor X deficiency: A hemorrhagic disease with variable presentation. Affected individuals can manifest prolonged nasal and mucosal hemorrhage, menorrhagia, hematuria, and occasionally hemarthrosis. Some patients do not have clinical bleeding diathesis.

Wikipedia:70 Factor X, also known by the eponym Stuart–Prower factor, is an enzyme (EC 3.4.21.6) of the coagulation... more...

Related Diseases for Factor X Deficiency

About this section

Diseases related to Factor X Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 144)
idRelated DiseaseScoreTop Affiliating Genes
1thrombophilia29.7F2, F5, SERPINC1
2thrombophilia due to antithrombin iii deficiency10.8
3familial glomangioma10.7F2, F3
4cerebral angioma10.7F2, F3
5epididymo-orchitis10.6F2, F3
6typhoid fever10.6F2, F7
7chorea gravidarum10.6F2, F3
8acute zonal occult outer retinopathy10.6F2, F5
9unicentric castleman disease10.6F2, F5
10peroneal neuropathy10.6F2, F3
11glossopharyngeal nerve disease10.6F10, F3
12diabetic autonomic neuropathy10.6F2, F9
13bartholin's gland adenoma10.6F2, F5
14splenic infarction10.6F2, F3
15secondary central precocious puberty10.6F10, VWF
16homocystinuria due to defect in methylation cbl g10.6F2, F5
17catatrichy10.6F3, F5
18primary pigmented nodular adrenocortical disease10.6F2, F5
19central epithelioid sarcoma10.5F2, VWF
20cercarial dermatitis10.5F2, F3
21pancreatic solid pseudopapillary carcinoma10.5F2, F7
22west nile fever10.5F2, F5
23inherited blood coagulation disease10.5F2, F3
24congenital nystagmus10.5F2, F3, F9
25brill-zinsser disease10.5F2, F3, F7
26central nervous system germinoma10.5F2, F3, F7
27penis papillary carcinoma10.5F10, F7, F9
28classic congenital lipoid adrenal hyperplasia due to star deficency10.5F2, F3, F5
29irak4 deficiency10.5F10, F2, F5
30parotid disease10.5F5, VWF
31cavernous sinus thrombosis10.5F3, SERPINC1
32retinal dystrophy, iris coloboma, and comedogenic acne syndrome10.5F10, F5
33milk allergy10.5F2, SERPINC1
34idiopathic central precocious puberty10.5F2, F3, F5
35hypertensive heart disease10.5F2, SERPINC1
36thrombocytopenia with elevated serum iga and renal disease10.5F2, F3, F5
37spleen cancer10.4F2, SERPINC1
38hepatocellular adenoma10.4F2, F5
39posterolateral myocardial infarction10.4F2, SERPINC1
40von willibrand disease, type 310.4F2, F3, VWF
41wfs1-related disorders10.4F2, F3, VWF
42histoplasmosis10.4F2, SERPINC1
43pneumocystosis10.4F11, F3
44tympanosclerosis10.4F2, F5, VWF
45ariboflavinosis10.4F2, F3, SERPINC1
46cavernous hemangioma of face10.3F2, F3, SERPINC1
47marek disease10.3F2, F3, SERPINC1
48ovarian gonadoblastoma10.3F2, F3, SERPINC1
49dmd-related dilated cardiomyopathy10.3F2, F3, SERPINC1
50amyloidosis10.3

Graphical network of the top 20 diseases related to Factor X Deficiency:



Diseases related to factor x deficiency

Symptoms for Factor X Deficiency

About this section

Symptoms by clinical synopsis from OMIM:

227600

Clinical features from OMIM:

227600

Human phenotypes related to Factor X Deficiency:

 63 (show all 9)
id Description HPO Frequency HPO Source Accession
1 menorrhagia63 HP:0000132
2 gingival bleeding63 HP:0000225
3 epistaxis63 HP:0000421
4 intracranial hemorrhage63 HP:0002170
5 prolonged partial thromboplastin time63 HP:0003645
6 joint hemorrhage63 HP:0005261
7 prolonged prothrombin time63 HP:0008151
8 reduced factor x activity63 HP:0008321
9 intramuscular hematoma63 HP:0012233

Drugs & Therapeutics for Factor X Deficiency

About this section

Drugs for Factor X Deficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 324)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Epinephrineapproved, vet_approvedPhase 4, Phase 293351-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
2
Hyaluronic acidapproved, vet_approvedPhase 44399004-61-953477741, 24759
Synonyms:
Hyaluronan
Hyaluronate
Hyaluronic acid
Hylartil
Hyruan Plus
Luronit
 
Macronan
Mucoitin
Nutra-HAF
Q 5AQ
Sepracoat
Sepragel Sinus
Sofast
Synvisc
3
Lidocaineapproved, vet_approvedPhase 41226137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
4
Cholecalciferolapproved, nutraceuticalPhase 4, Phase 2, Phase 385167-97-06221, 10883523, 5280795
Synonyms:
()-Vitamin D3
(+)-Vitamin D3
(+)-vitamin D3
(1S,3Z)-3-[(2e)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol
(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7e)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol
(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(5Z,7e)-(3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
1406-16-2
25(OH)D
3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol
47763_SUPELCO
57651-82-8
67-97-0
7-Dehydrocholesterol activated
7-Dehydrocholesterol, Activated
7-Dehydrocholesterol, irradiated
7-Dehydrocholestrol, activated
8024-19-9
8050-67-7
89193_FLUKA
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol
9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol
9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol
9,10-Secocholesta-5,7,10(19)-trien-3-ol
9,10-Secocholesta-5,7,10-trien-3-ol
AB1002422
AC-11697
AC1L1ECK
AC1L1M23
AC1LU7IZ
AC1NQXLN
AC1NR2UO
AC1NR2UR
AC1NR2UU
AC1NS4AJ
AC1NSHJX
AC1O5EOF
AC1O7GAV
AC1O7GQ3
AC1O8FEU
AC1O8PWJ
AC1OF2GI
AC1OF2GL
AC1OIEW5
AC1OIEWB
ACon1_001997
Activated 7-dehydrocholesterol
Arachitol
BPBio1_000460
BSPBio_000418
BSPBio_002408
Bio-0845
C05443
C1357_SIAL
C27H44O
C9756_SIGMA
C9774_SIAL
CAS-67-97-0
CC
CCRIS 5813
CCRIS 6286
CHEBI:283119
CHEBI:28940
CHEMBL1042
CHEMBL432780
CID10000117
CID10045875
CID10340013
CID10883523
CID10894379
CID11014566
CID11025493
CID11058152
CID11463269
CID1548921
CID2735
CID5280795
CID5283710
CID5283711
CID5283712
CID5353527
CID5363362
CID6221
CID6432644
CID6604201
CID6604662
CID6708595
CID6713938
CID6992015
CID6992016
CID7067439
CID7067440
CID7251172
CID7251174
CID9821465
Calciol
Cholecalciferol
Cholecalciferol (D3)
Cholecalciferol (JP15/USP)
Cholecalciferol D3
Cholecalciferol [USAN:BAN:JAN]
Cholecalciferol, D3
Cholecalciferolum
 
Colecalciferol
Colecalciferol (INN)
Colecalciferolo
Colecalciferolo [DCIT]
Colecalciferolum
Colecalciferolum [INN-Latin]
Colecalcipherol
D00188
D3-Vicotrat
D3-Vigantol
DB00169
Delsterol
Delta-D
Delta-D (TN)
Deparal
Devaron
DivK1c_006276
Duphafral D3 1000
EINECS 200-673-2
EINECS 215-797-2
EPA Pesticide Chemical Code 202901
Ebivit
FeraCol
Granuvit D3
HMS1569E20
HMS2092M12
HSDB 820
I05-0041
Irradiated 7-dehydrocholesterol
KBio1_001220
KBio2_001643
KBio2_004211
KBio2_006779
KBio3_001628
KBioGR_001602
KBioSS_001643
LMST03020001
LMST03020219
LMST03020220
LMST03020221
LS-1570
LS-825
LT00244775
MEGxm0_000458
Micro-dee
MolPort-001-740-051
MolPort-001-785-972
MolPort-003-666-021
MolPort-004-946-964
NCGC00016301-01
NCGC00017328-01
NCGC00091072-01
NCGC00142511-01
NCGC00159331-02
NCGC00159331-04
NCGC00178668-01
NCGC00179565-01
NCGC00179565-02
NEO Dohyfral D3
NSC 375571
NSC-375571
NSC375571
Oleovitamin D3
Prestwick0_000429
Prestwick1_000429
Prestwick2_000429
Prestwick3_000429
Prestwick_63
Provitamine
Provitina
Quintox
Rampage
Ricketon
SMP1_000068
SPBio_001298
SPBio_002357
SR-05000001559
SR-05000001559-3
ST057172
SpecPlus_000180
Spectrum2_001369
Spectrum3_000764
Spectrum4_001201
Spectrum_001163
TNP00266
Trivitan
UNII-1C6V77QF41
UPCMLD-DP152
UPCMLD-DP152:001
VITAMIN D
VITAMIN D3 POWDER
VITAMIN_D3
Vi-De3
Vi-de-3-hydrosol
VidDe-3-hydrosol
Videkhol
Vigantol
Vigorsan
Vitamin D3
Vitamin D3 emulsifiable
Vitinc Dan-Dee-3
ZINC04474460
ZINC04492874
ZINC04492875
ZINC04492876
ZINC04492878
bmse000507
calciol
cholecalciferol
delta-D
vitamin d-3
5
Ergocalciferolapproved, nutraceuticalPhase 4, Phase 2, Phase 3123250-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2
6
Phytonadioneapproved, NutraceuticalPhase 423084-80-04812, 5284607
Synonyms:
.alpha.-Phylloquinone
1,4-Naphthalenedione, 2-methyl-3-((2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl)-, radical ion(1-)
10485-69-5
11104-38-4
15973-57-6
2', 3'-trans-Vitamin K1
2',3'-trans-Vitamin K1
2-(3,7,11,15-Tetramethylhexadec-2-enyl)-3-methylnaphthalene-1,4-dione
2-METHYL-3-PHYTYL-14-NAPHTHOQUINONE
2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalened- ione
2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione
2-Methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)-1,4-naphthoquinone
2-Methyl-3-[(2e)-3,7,11,15-tetramethyl-2-hexadecenyl]naphthoquinone
2-Methyl-3-phythyl-1,4-naphthochinon
2-Methyl-3-phytyl-1,4-naphthochinon
2-Methyl-3-phytyl-1,4-naphthochinon [German]
2-Methyl-3-phytyl-1,4-naphthoquinone
2-methyl-3-(3,7,11,15-tetramethylhexadec-2-en-1-yl)naphthalene-1,4-dione
2-methyl-3-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione
27696-10-2
3-Phytylmenadione
50926-17-5
84-80-0
AC1NQX34
AC1Q6B3J
AR-1E3503
Antihemorrhagic vitamin
Aqua mephyton
Aqua-Mephytin
Aquamephyton
C02059
C31H46O2
CID5280483
Combinal K1
D00148
DB01022
EINECS 201-564-2
EINECS 234-330-3
EINECS 279-833-9
Fitomenadiona
Fitomenadiona [INN-Spanish]
Fitomenadione
Fitomenadione [DCIT]
HSDB 3162
K-Ject
Kativ N
Kephton
 
Kinadion
Konakion
LS-94617
LT00452032
MLS001332659
MLS001332660
Mephyton
Mephyton (TN)
MolPort-001-785-978
Mono-Kay
Monodion
NCGC00159423-02
NSC 270681
NSC270681
P0642
Phyllochinon
Phyllochinon [German]
Phyllochinonum
Phylloquinone
Phylloquinone (8CI)
Phythyl-menadion
Phythyl-menadion (GERMAN)
Phytomenadione
Phytomenadione (INN)
Phytomenadionum
Phytomenadionum [INN-Latin]
Phytonadione
Phytonadione (JP15/USP)
Phytonadione [USAN:JAN]
Phytonadionum
Phytylmenadione
SMR000059144
ST075162
Synthex P
UNII-A034SE7857
VITAMIN K
VITAMIN K1
Vitamin K
Vitamin K 1
Vitamin K1
Vitamin K1 (TN)
Vitamin K1 (VAN)
Vitamin K1 (generic)
Vitamin K1(20)
alpha-Phylloquinone
phyllohydroquinone
phytonadione
trans-Phylloquinone
α-phylloquinone
7
Menadioneapproved, nutraceuticalPhase 423058-27-54055
Synonyms:
03AAE1E9-B215-45AF-976C-91E61894A467
1,4-Naphthalenedione, 2-methyl-, radical ion(1-)
2-Methyl-1,4-Naphthalenedione
2-Methyl-1,4-naftochinon
2-Methyl-1,4-naftochinon [Czech]
2-Methyl-1,4-naphthalendione
2-Methyl-1,4-naphthalenedione
2-Methyl-1,4-naphthochinon
2-Methyl-1,4-naphthochinon [German]
2-Methyl-1,4-naphthodione
2-Methyl-1,4-naphthoquinone
2-Methylnaphthoquinone
2-methyl-1,4-naphthoquinone, 5
2-methylnaphthalene-1,4-dione
3-Methyl-1,4-naphthoquinone
34524-96-4
47775_SUPELCO
58-27-5
72060-21-0
AC1L1HBA
AC1Q2HB3
AI3-14700
AKOS004910447
ARONIS24154
Aquakay
Aquinone
BB_NC-2319
BIDD:ER0556
BPBio1_000592
BSPBio_000538
Bio1_000471
Bio1_000960
Bio1_001449
C05377
C11H8O2
CAS-58-27-5
CCRIS 6672
CHEBI:28869
CHEMBL590
CID4055
CPD-3766
D02335
DB00170
DivK1c_000080
DivK1c_006287
EINECS 200-372-6
HMS1569K20
HMS1921P06
HMS2092F12
HMS500D22
HSDB 3354
Hemodal
I14-2821
IDI1_000080
InChI=1/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H
Juva-K
K-Thrombyl
K-Vitan
KBio1_000080
KBio1_001231
KBio2_001708
KBio2_002527
KBio2_004276
KBio2_005095
KBio2_006844
KBio2_007663
KBio3_003005
KBioGR_000984
KBioGR_002527
KBioSS_001708
KBioSS_002535
Kaergona
Kanone
Kappaxan
Kappaxan (VAN)
Kappaxin
Kappaxin (TN)
Karcon
Kareon
Kativ-G
Kayklot
Kaykot
 
Kaynone
Kayquinone
Kipca
Kipca, oil soluble
Kipca-Oil Soluble
Klottone
Koaxin
Kolklot
LS-95653
LS-95654
M0373
M5625_SIGMA
M9429_SIGMA
MLS000069420
MLS001148443
MNQ
Memodol
Menadion
Menadione
Menadione (K3)
Menadione (USP)
Menadione [USAN:BAN]
Menadione semiquinone
Menadionum
Menaphthene
Menaphthon
Menaphthone
Menaphtone
Menaquinone
Menaquinone 0
Menaquinone O
Methyl-1,4-naphthalenedione
Methyl-1,4-naphthoquinone
Methylnaphthoquinone
Mitenon
Mitenone
MolPort-001-766-699
NCGC00016258-01
NCGC00094978-01
NCGC00094978-02
NCI60_003945
NCIMech_000105
NINDS_000080
NSC 4170
NSC4170
Panosine
Prestwick0_000459
Prestwick1_000459
Prestwick2_000459
Prestwick3_000459
Prestwick_313
Prokayvit
QTL1_000056
S1949_Selleck
SMR000059102
SMR000653532
SPBio_001267
SPBio_002477
SPECTRUM1502254
SpecPlus_000191
Spectrum2_001194
Spectrum4_000722
Spectrum5_001764
Spectrum_001228
Synkay
Thyloquinone
UNII-723JX6CXY5
Usaf ek-5185
VK3
Vicasol
Vitamin K 3
Vitamin K0
Vitamin K2
Vitamin K2(0)
Vitamin K3
Vitamin K3 : 2-Methyl-1,4-naphthoquinone
Vitamin K3: 1,4-Dihydro-1,4-dioxo-2-methylnaphthalene
Vitamin-?K3
WLN: L66 BV EVJ C1
ZINC00001677
cMAP_000077
menadione
nchembio.109-comp5
8Pharmaceutical SolutionsPhase 4, Phase 3, Phase 2, Phase 17793
9Adjuvants, ImmunologicPhase 4, Phase 2, Phase 3, Phase 12484
10HormonesPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 113979
11Hormone AntagonistsPhase 4, Phase 2, Phase 3, Phase 112778
12VaccinesPhase 4, Phase 3, Phase 2, Phase 16428
13AntimetabolitesPhase 4, Phase 3, Phase 1, Phase 211774
14ErgocalciferolsPhase 4, Phase 2, Phase 31232
15CoagulantsPhase 4, Phase 3, Phase 2, Phase 11428
16Bone Density Conservation AgentsPhase 4, Phase 2, Phase 33266
17Factor VIIIPhase 4, Phase 1, Phase 2304
18MicronutrientsPhase 4, Phase 2, Phase 3, Phase 15802
19Trace ElementsPhase 4, Phase 2, Phase 3, Phase 15802
20vitamin dPhase 4, Phase 2, Phase 31653
21Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 2, Phase 3, Phase 112767
22VitaminsPhase 4, Phase 2, Phase 3, Phase 15095
23Rho(D) Immune GlobulinPhase 4, Phase 3, Phase 2317
24Anesthetics, LocalPhase 43272
25AnestheticsPhase 49001
26RacepinephrinePhase 4, Phase 2933
27Calcium, DietaryPhase 4, Phase 2, Phase 35525
28Immunoglobulin GPhase 4, Phase 3, Phase 2, Phase 1265
29Immunoglobulins, IntravenousPhase 4, Phase 3, Phase 2324
30Protective AgentsPhase 4, Phase 2, Phase 3, Phase 17190
31Epinephryl boratePhase 4, Phase 2933
32ViscosupplementsPhase 4364
33AnticoagulantsPhase 4, Phase 3, Phase 22516
34Antifibrinolytic AgentsPhase 4459
35ThrombinPhase 4, Phase 3, Phase 2288
36HemostaticsPhase 4, Phase 3, Phase 21359
37Vitamin MK 7Phase 440
38Vitamin K 2Phase 440
39Antiviral AgentsPhase 4, Phase 3, Phase 2, Phase 19732
40AntibodiesPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 16045
41gamma-GlobulinsPhase 4, Phase 3, Phase 2317
42ImmunoglobulinsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 16045
43Hypolipidemic AgentsPhase 4, Phase 1, Phase 22721
44Lipid Regulating AgentsPhase 4, Phase 1, Phase 22702
45Hydroxymethylglutaryl-CoA Reductase InhibitorsPhase 41956
46Atorvastatin CalciumPhase 4743134523-03-8
47Anticholesteremic AgentsPhase 41983
48Vitamin D2NutraceuticalPhase 4, Phase 2, Phase 31232
49CalciferolNutraceuticalPhase 4, Phase 2, Phase 31334
50Omega 3 Fatty AcidNutraceuticalPhase 4, Phase 3969

Interventional clinical trials:

(show top 50)    (show all 265)
idNameStatusNCT IDPhase
1Subclinical Joint Bleeding in Irish Adults With Severe Haemophilia A on Personalised Prophylaxis RegimensUnknown statusNCT02314325Phase 4
2Effect of Vitamin D on Metabolic Parameters in Patients With the Metabolic SyndromeUnknown statusNCT01237769Phase 4
3The Role Of FGF23, Klotho, And Sclerostin In Kidney Stone FormersUnknown statusNCT01526304Phase 4
4Efficacy and Safety of Prothromplex Total (Prothrombin Complex Concentrate) in Oral Anticoagulant ReversalCompletedNCT01159210Phase 4
5Risk Factors for Vascular Calcifications in Hemodialysis Patients: to What Extent is Vitamin K2 Deficiency Involved?CompletedNCT02876354Phase 4
6GH and Cardiovascular Risk FactorsCompletedNCT01877512Phase 4
7Effect of Somatropin on Left Ventricular Mass in Growth Hormone Deficient Adult PatientsCompletedNCT01562834Phase 4
8Omacor and Cardiovascular Risk Factors in HIV Patients on HAART TreatmentCompletedNCT00296153Phase 4
9Magnesium and Metabolic SyndromeCompletedNCT00603499Phase 4
10Pharmacokinetics, Safety, and Tolerability of Subcutaneous GAMUNEX-C in Pediatric Subjects With Primary ImmunodeficiencyCompletedNCT01465958Phase 4
11A Study to Find Out How Safe and Effective Gammaplex® is in Young People With Primary ImmunodeficiencyCompletedNCT01289847Phase 4
12Hyaluronic Acid in Papillary ReconstructionCompletedNCT02876276Phase 4
13Efficacy and Safety of Vivaglobin® in Previously Untreated Patients With Primary ImmunodeficiencyCompletedNCT00520494Phase 4
14Hepatitis B Vaccine Genetics: A Substudy of ATN 024 and ATN 025CompletedNCT00142740Phase 4
15Modulation of Monocyte Activation by Atorvastatin in HIV InfectionActive, not recruitingNCT01263938Phase 4
16Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X]Unknown statusNCT01109498Phase 2, Phase 3
17A Study Investigating Treatment Factor X in People With Factor X DeficiencyCompletedNCT00930176Phase 3
18A Study to Investigate BPL's Factor X in the Prophylaxis of Bleeding in Children <12 YearsCompletedNCT01721681Phase 3
19Prothrombin Complex Concentrate for Anticoagulant ReversalCompletedNCT00168077Phase 3
20The Effect of Vitamin D and Calcium on Bone in Pediatric HIVCompletedNCT00724178Phase 2, Phase 3
21Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient SubjectsCompletedNCT00891306Phase 2, Phase 3
22Safety and Efficacy Study of Serostim® Human Immunodeficiency Virus-Associated Adipose Redistribution SyndromeCompletedNCT01077960Phase 3
23Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency DiseasesCompletedNCT01963143Phase 3
24Treating Depression in Coronary Artery Disease With Omega-3 Fatty AcidsCompletedNCT00981383Phase 3
25Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases.CompletedNCT00278954Phase 3
26Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement TherapyCompletedNCT00542997Phase 3
27Effectiveness of Paricalcitol in Reducing Parathyroid Hormone (PTH) Levels in X-linked Hypophosphatemic RicketsCompletedNCT00417612Phase 3
28Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PIDCompletedNCT01175213Phase 3
29Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency PatientsCompletedNCT00220766Phase 3
30The Efavirenz (EFV) Central Nervous System Exposure Sub-study of Encore1CompletedNCT01451333Phase 3
31WENBIT - Western Norway B Vitamin Intervention TrialCompletedNCT00354081Phase 3
32Study Comparing Lopinavir/Ritonavir (LPV/r) + Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) With a Nucleoside Sparing Regimen Consisting of Lopinavir/Ritonavir + Raltegravir (RAL)CompletedNCT00711009Phase 3
33Evaluation of a Lopinavir/Ritonavir Monotherapy vs a Triple Therapy as Maintenance Regimens in HIV-1 Infected PatientsCompletedNCT00946595Phase 2, Phase 3
34Study Comparing Efficacy and Safety of Darunavir Boosted With Ritonavir to HART With 2 NRTI and Darunavir Boosted With Ritonavir in HIV-1 Infected Patients ANRS136CompletedNCT00421551Phase 3
35BMS-Reyataz Study in Treatment in Naive Subjects to Compare the Efficacy and Safety Between Boosted Reyataz and Kaletra When in Combination With Fixed Dose TruvadaCompletedNCT00272779Phase 3
36Stem Cell Transplant for Inborn Errors of MetabolismCompletedNCT00176904Phase 2, Phase 3
37The Effect of Vitamin D Supplementation on Cardiovascular Risk FactorsRecruitingNCT02750293Phase 3
38Efficacy and Safety of KRN23 Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With X Linked Hypophosphatemia (XLH)RecruitingNCT02915705Phase 3
39Effects of Interleukin-1 Beta on Low Testosterone Levels in Men With Obesity and Metabolic SyndromeRecruitingNCT02672592Phase 3
40DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a 2nd Year of Life Booster in HIV-Exposed Infected and UninfectedRecruitingNCT02817451Phase 3
41Pivotal Phase 2b/3 ALVAC/Bivalent gp120/MF59 HIV Vaccine Prevention Safety and Efficacy Study in South AfricaRecruitingNCT02968849Phase 2, Phase 3
42Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic LeukaemiaRecruitingNCT01949129Phase 2, Phase 3
43Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH)Active, not recruitingNCT02537431Phase 3
44Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH)Active, not recruitingNCT02526160Phase 3
45Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency DiseasesActive, not recruitingNCT01884311Phase 3
46T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic DisordersActive, not recruitingNCT00176826Phase 2, Phase 3
47Neo Adjuvant Chemotherapy in Triple Negative Breast CancerActive, not recruitingNCT01057069Phase 2, Phase 3
48Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon CancerActive, not recruitingNCT00217737Phase 3
49Trial of HDM/SCT Versus HDM + Bortezomib/SCT in AL AmyloidosisSuspendedNCT02489500Phase 3
50Safety & Efficacy of BPL's High Purity FACTOR X in Treatment of Factor X Deficient Subjects Undergoing SurgeryTerminatedNCT01086852Phase 3

Search NIH Clinical Center for Factor X Deficiency


Cochrane evidence based reviews: factor x deficiency

Genetic Tests for Factor X Deficiency

About this section

Genetic tests related to Factor X Deficiency:

id Genetic test Affiliating Genes
1 Factor X Deficiency26 24 F10

Anatomical Context for Factor X Deficiency

About this section

MalaCards organs/tissues related to Factor X Deficiency:

35
Bone, Liver, Bone marrow, Skin, Lung, Testes, Breast

Animal Models for Factor X Deficiency or affiliated genes

About this section

MGI Mouse Phenotypes related to Factor X Deficiency:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053808.9F2, F3, F5, F9, SERPINC1, SSB
2MP:00053858.2F10, F11, F2, F3, F5, F7
3MP:00053767.7F10, F11, F2, F3, F5, F7
4MP:00107686.9F10, F11, F2, F3, F5, F7

Publications for Factor X Deficiency

About this section

Articles related to Factor X Deficiency:

(show top 50)    (show all 219)
idTitleAuthorsYear
1
Synergistic effect of factor VII gene polymorphisms causing mild factor VII deficiency in a case of severe factor X deficiency. (26919454)
2016
2
Spectrum of factor X gene mutations in Iranian patients with congenital factor X deficiency. (26891460)
2016
3
Pharmacokinetics of a high-purity plasma-derived factor X concentrate in subjects with moderate or severe hereditary factor X deficiency. (26879266)
2016
4
Prevalence of bleeding manifestations in 128 heterozygotes for Factor X deficiency, mainly for FX Friuli, matched vs 128 unaffected family members, during a long sequential observation period (23.5 years). (27124643)
2016
5
A family with factor X deficiency from Argentina: a compound heterozygosis because of the combination of a new mutation (Gln138Arg) with an already known one (Glu350Lys). (27031279)
2016
6
A novel factor X gene mutation Val (GTC) 384Ala (GCC) in a Chinese family resulting in congenital factor X deficiency. (26309706)
2015
7
Surgical treatment for a paraplegic patient induced by congenital factor X deficiency. (26550274)
2015
8
Frequency of the p.Gly262Asp mutation in congenital Factor X deficiency. (26222694)
2015
9
Molecular analysis of patients with severe congenital factor X deficiency: First report from north and northwest of Iran. (25984924)
2015
10
Circumcision in Patients with Congenital Factor X Deficiency. (24972549)
2014
11
Life-threatening bleeding tendency provoked by an acquired isolated factor X deficiency associated with respiratory infection. (23463452)
2013
12
Acquired, non-amyloid related factor X deficiency: review of the literature. (23437437)
2012
13
Factor X deficiency: an uncommon presentation of AL amyloidosis. (22651249)
2012
14
Acquired factor X deficiency in light chain amyloidosis: a report of 2 Korean cases. (21779187)
2011
15
Factor X deficiency presenting with bilateral chronic subdural hematoma. (20516741)
2010
16
Factor X deficiency. (20734884)
2010
17
Subclinical factor X deficiency may increase hemorrhage in women undergoing cesarean section. (20605440)
2010
18
Pregnancy in a patient with severe factor X deficiency. (19765091)
2009
19
Phenotype and genotype report on homozygous and heterozygous patients with congenital factor X deficiency. (18403394)
2008
20
Report on a disease-adapted treatment in a patient with severe factor X deficiency resulting from a homozygous factor X gene mutation. (18217161)
2008
21
Molecular characterization of two novel mutations causing factor X deficiency in a Chinese pedigree. (15660986)
2005
22
Resolution of acquired factor X deficiency with amyloidosis secondary to plasma cell dyscrasia. (15551292)
2004
23
Two novel factor X gene mutations in a Chinese family with factor X deficiency. (15060750)
2004
24
Successful treatment of systemic amyloidosis with hepatic involvement and factor X deficiency by high dose melphalan chemotherapy and autologous stem cell reinfusion. (14962236)
2004
25
Secondary severe factor X deficiency associated with antiphospholipid syndrome. (15224378)
2004
26
Gene mutations and three-dimensional structural analysis in 13 families with severe factor X deficiency. (12028042)
2002
27
Danazol therapy in factor X deficiency. (11554940)
2001
28
Decreased Quick percentage, acquired factor X deficiency, hemarthrosis and ecchymosis: amyloidosis]. (10517125)
1999
29
Factor X Frankfurt I: molecular and functional characterization of a hereditary factor X deficiency (Gla+25 to Lys). (9622212)
1998
30
Splenectomy in an uraemic patient with acquired factor X deficiency due to AL amyloidosis. (9481739)
1998
31
A functional factor X deficiency. (7832186)
1995
32
Congenital blood coagulation factor X deficiency. Successful result of the use prothrombin concentrated complex in the control of ++cesarean section hemorrhage in 2 pregnancies]. (7659886)
1994
33
Recurrent, isolated factor X deficiency in myeloma: repeated normalization of factor X levels after cytostatic chemotherapy followed by late treatment failure associated with the development of systemic amyloidosis. (1287879)
1992
34
Acquired factor X deficiency and disseminated intravascular coagulation in a case of metastasizing carcinoma of the stomach and its course under chemotherapy. (1571411)
1992
35
A case of acquired factor X deficiency with in vivo and in vitro evidence of inhibitor activity directed against factor X. (1862774)
1991
36
Partial gene deletion in a family with factor X deficiency. (2567188)
1989
37
Factor X deficiency during treatment of relapsed acute myeloid leukaemia with amsacrine. (3166416)
1988
38
Severe congenital factor X deficiency with intracranial haemorrhage. (3732313)
1986
39
Novel factor X deficiency. Normal partial thromboplastin time and associated spindle cell thymoma. (4014297)
1985
40
Prolongation of thrombin and reptilase times in patients with amyloidosis and acquired factor X deficiency. (6372111)
1984
41
A new family with classical factor X deficiency as demonstrated by electroimmunoassay. (6860802)
1983
42
Factor X deficiency in systemic amyloidosis. (7242595)
1981
43
Acquired factor X deficiency with associated defects in platelet aggregation. A response to corticosteroid therapy. (7386500)
1980
44
Acquired isolated factor X deficiency associated with systemic amyloidosis. Case report and review of literature. (7442086)
1980
45
Chronic peritoneal dialysis in a patient with primary amyloidosis, renal failure, and factor X deficiency. (96536)
1978
46
Syndrome of acquired factor X deficiency and systemic amyloidosis in vivo studies of the metabolic fate of factor X. (865580)
1977
47
Treatment of amyloidosis associated factor X deficiency. (989637)
1976
48
Factor X level in coumarin treated patients and in factor X deficiency as assayed with different techniques. (5050158)
1972
49
Amyloidosis with factor X deficiency. (4650132)
1972
50
Severe congenital factor X deficiency in 5-month-old child. (5483958)
1970

Variations for Factor X Deficiency

About this section

UniProtKB/Swiss-Prot genetic disease variations for Factor X Deficiency:

69 (show all 26)
id Symbol AA change Variation ID SNP ID
1F10p.Glu47GlyVAR_065428rs121964943
2F10p.Gly51ValVAR_065429rs751782758
3F10p.Glu54GlyVAR_065430rs121964944
4F10p.Glu54LysVAR_065431rs121964939
5F10p.Glu72GlnVAR_065432rs121964945
6F10p.Glu91LysVAR_065433
7F10p.Cys149TyrVAR_065435
8F10p.Cys151TyrVAR_065436
9F10p.Gly289ArgVAR_065437rs121964946
10F10p.Glu304LysVAR_065438rs747292771
11F10p.Asp322AsnVAR_065439rs121964942
12F10p.Arg327TrpVAR_065440rs770119164
13F10p.Val338MetVAR_065441rs121964947
14F10p.Glu350LysVAR_065442rs372309538
15F10p.Thr358MetVAR_065443rs768222784
16F10p.Gly363SerVAR_065444
17F10p.Arg366CysVAR_065445rs104894392
18F10p.Ser374ProVAR_065446rs121964941
19F10p.Pro383SerVAR_065447rs121964940
20F10p.Cys390PheVAR_065448rs199778916
21F10p.Cys404ArgVAR_065449
22F10p.Gly406SerVAR_065450rs376163818
23F10p.Gly420ArgVAR_065451rs750759634
24F10p.Lys448AsnVAR_065452
25F10p.Val382AlaVAR_072751
26F10p.Gly421AspVAR_072752rs758726161

Clinvar genetic disease variations for Factor X Deficiency:

5 (show all 15)
id Gene Variation Type Significance SNP ID Assembly Location
1F10NM_000504.3(F10): c.1096C> T (p.Arg366Cys)SNVPathogenicrs104894392GRCh37Chr 13, 113803460: 113803460
2F10NM_000504.3(F10): c.813delC (p.Leu272Terfs)deletionPathogenicrs387906506GRCh37Chr 13, 113801758: 113801758
3F10F10, GLU14LYSSNVPathogenicChr na, -1: -1
4F10F10, VAL298METundetermined variantPathogenicChr na, -1: -1
5F10F10, PRO343SERSNVPathogenicChr na, -1: -1
6F10F10, G-A, -20SNVPathogenicChr na, -1: -1
7F10NM_000504.3(F10): c.859A> T (p.Arg287Trp)SNVPathogenicrs121964948GRCh38Chr 13, 113147490: 113147490
8F10F10, SER334PROundetermined variantPathogenicChr na, -1: -1
9F10NM_000504.3(F10): c.424G> A (p.Glu142Lys)SNVPathogenicrs61753266GRCh37Chr 13, 113795286: 113795286
10F10F10, ASP282ASNundetermined variantPathogenicChr na, -1: -1
11F10F10, GLU7GLYSNVPathogenicChr na, -1: -1
12F10Factor X KetchikanSNVPathogenicChr na, -1: -1
13F10F10, GLU32GLNSNVPathogenicChr na, -1: -1
14F10;F7NM_000131.4(F7): c.1238G> A (p.Arg413Gln)SNVrisk factorrs6046GRCh37Chr 13, 113773159: 113773159
15F10F10, THR318METundetermined variantPathogenicChr na, -1: -1

Expression for genes affiliated with Factor X Deficiency

About this section
Search GEO for disease gene expression data for Factor X Deficiency.

Pathways for genes affiliated with Factor X Deficiency

About this section

GO Terms for genes affiliated with Factor X Deficiency

About this section

Cellular components related to Factor X Deficiency according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intrinsic component of external side of plasma membraneGO:003123310.8F10, F3
2platelet alpha granuleGO:003109110.6F5, VWF
3Golgi lumenGO:000579610.0F10, F2, F7, F9
4endoplasmic reticulum lumenGO:00057889.7F10, F2, F5, F7, F9
5extracellular spaceGO:00056158.1F11, F2, F3, F5, F7, F9
6extracellular regionGO:00055767.8F10, F11, F2, F5, F7, F9
7plasma membraneGO:00058867.0F10, F11, F2, F3, F5, F7

Biological processes related to Factor X Deficiency according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of platelet-derived growth factor receptor signaling pathwayGO:001064110.6F3, F7
2positive regulation of positive chemotaxisGO:005092710.5F3, F7
3regulation of blood coagulationGO:003019310.4F11, F2
4positive regulation of protein kinase B signalingGO:005189710.1F10, F3, F7
5positive regulation of blood coagulationGO:003019410.0F2, F7
6peptidyl-glutamic acid carboxylationGO:001718710.0F10, F2, F7, F9
7signal peptide processingGO:000646510.0F10, F2, F7, F9
8platelet activationGO:00301689.8F2, F5, VWF
9blood coagulation, extrinsic pathwayGO:00075989.7F10, F3, F7, F9, TFPI
10blood coagulation, intrinsic pathwayGO:00075979.6F10, F11, F2, F9, VWF
11response to estradiolGO:00323559.6F3, F7, TFPI
12ER to Golgi vesicle-mediated transportGO:00068889.5F10, F2, F5, F7, F9
13blood coagulationGO:00075967.3F10, F11, F2, F3, F5, F7

Molecular functions related to Factor X Deficiency according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00020209.4F3, SERPINC1, VWF
2serine-type endopeptidase activityGO:00042528.4F10, F11, F2, F3, F5, F7

Sources for Factor X Deficiency

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet