MCID: FCT022
MIFTS: 56

Factor Xi Deficiency, Autosomal Recessive malady

Categories: Genetic diseases, Rare diseases, Immune diseases, Blood diseases

Aliases & Classifications for Factor Xi Deficiency, Autosomal Recessive

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Aliases & Descriptions for Factor Xi Deficiency, Autosomal Recessive:

Name: Factor Xi Deficiency, Autosomal Recessive 51
Factor Xi Deficiency 51 11 47 24 69 49 38 13 67
Plasma Thromboplastin Antecedent Deficiency 11 47 53 69
Hemophilia C 11 47 53 69
Congenital Factor Xi Deficiency 11 47 53
Rosenthal Factor Deficiency 47 53 69
Rosenthal Syndrome 47 53 69
 
Pta Deficiency 47 53 69
Factor Xi Deficiency, Autosomal Dominant 51 12
Hereditary Factor Xi Deficiency Disease 11 26
F11 Deficiency 47 69
Factor 11 Deficiency 69
Rosenthal's Disease 11
Fa11d 69

Characteristics:

Orphanet epidemiological data:

53
plasma thromboplastin antecedent deficiency:
Inheritance: Autosomal dominant,Autosomal recessive; Age of onset: All ages; Age of death: normal life expectancy

HPO:

63
factor xi deficiency, autosomal recessive:
Inheritance: autosomal dominant inheritance, autosomal recessive inheritance

Classifications:



External Ids:

OMIM51 612416
Disease Ontology11 DOID:2229
ICD1029 D68.1
ICD9CM31 286.2
MeSH38 D005173
SNOMED-CT61 49762007
NCIt44 C84705
Orphanet53 ORPHA329
ICD10 via Orphanet30 D68.1
MedGen36 C0015523

Summaries for Factor Xi Deficiency, Autosomal Recessive

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NIH Rare Diseases:47 Factor XI deficiency is a bleeding disorder that interferes with the body's clotting process. As a result, people affected by this condition may have difficulty stopping the flow of blood following dental extractions, trauma or surgery. Women with factor XI deficiency may also experience heavy menstrual periods or heavy postpartum bleeding. Within affected people and their families, highly variable bleeding patterns occur, and bleeding risk can not be predicted by the level of factor XI (a clotting factor) in the blood. Although the condition can affect people of all heritages, it is most common in people of Ashkenazi Jewish descent. Most cases of factor XI deficiency are inherited and caused by changes (mutations) in the F11 gene. In most cases the condition is inherited in an autosomal recessive manner however, it may follow an autosomal dominant pattern in some families. Treatment is often only recommended during periods of high bleeding risk (i.e. surgery) and may include fresh frozen plasma and/or antifibrinolytics (medications that improve blood clotting). Factor XI concentrates may be available for factor replacement in some countries. Last updated: 2/5/2016

MalaCards based summary: Factor Xi Deficiency, Autosomal Recessive, also known as factor xi deficiency, is related to thrombophilia and myocardial infarction, and has symptoms including abnormal bleeding, reduced factor xi activity and prolonged partial thromboplastin time. An important gene associated with Factor Xi Deficiency, Autosomal Recessive is F11 (Coagulation Factor XI), and among its related pathways are Platelet Aggregation Inhibitor Pathway, Pharmacodynamics and Gamma carboxylation, hypusine formation and arylsulfatase activation. Affiliated tissues include brain, liver and endothelial, and related mouse phenotypes are hematopoietic system and immune system.

UniProtKB/Swiss-Prot:69 Factor XI deficiency: A hemorrhagic disease characterized by reduced levels and activity of factor XI resulting in moderate bleeding symptoms, usually occurring after trauma or surgery. Patients usually do not present spontaneous bleeding but women can present with menorrhagia. Hemorrhages are usually moderate.

OMIM:51 Factor XI deficiency is an autosomal bleeding disorder characterized by reduced levels of factor XI in plasma (less... (612416) more...

Related Diseases for Factor Xi Deficiency, Autosomal Recessive

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Diseases related to Factor Xi Deficiency, Autosomal Recessive via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 167)
idRelated DiseaseScoreTop Affiliating Genes
1thrombophilia29.4F2, F5
2myocardial infarction26.7F11, F2, F3, F5, F7, F8
3melkersson-rosenthal syndrome12.5
4pneumocystosis10.4F11, F3
5familial glomangioma10.4F2, F3
6ariboflavinosis10.4F2, F3
7myiasis10.4F2, F3
8cavernous hemangioma of face10.4F2, F3
9ovarian gonadoblastoma10.4F2, F3
10cerebral angioma10.4F2, F3
11high anorectal malformation10.4F8, F9
12epididymo-orchitis10.4F2, F3
13chorea gravidarum10.4F2, F3
14dmd-related dilated cardiomyopathy10.4F2, F3
15lateral cystocele10.3F2, F3
16peroneal neuropathy10.3F2, F3
17splenic infarction10.3F2, F3
18lymphatic system cancer10.3F2, F3
19prostatic hypertrophy10.3F11, F8
20cercarial dermatitis10.3F2, F3
21artery disease10.3F2, F3
22intracranial arteriosclerosis10.3F2, F3
23chronic diarrhea due to guanylate cyclase 2c overactivity10.3F3, VWF
24central epithelioid sarcoma10.3F2, VWF
25dermatitis10.3F2, F3
26ovarian cystic teratoma10.3F2, F3
27idiopathic neutropenia10.2F3, F8
28tyrobp-related polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy10.2F8, VWF
29tyrosine hydroxylase-deficient dopa-responsive dystonia10.2F8, VWF
30secondary central precocious puberty10.2F8, VWF
31familial spastic paralysis10.2F8, VWF
32type 2n von willebrand disease10.2F8, VWF
33colon carcinoma in situ10.2F3, VWF
34malignant type ab thymoma10.2F8, VWF
35cheilitis10.2
36typhoid fever10.2F2, F7
37tollner horst manzke syndrome10.2F3, F8
38psychologic dyspareunia10.2F2, VWF
39esophagus leiomyosarcoma10.2F7, F9
40hepatic coma10.2F2, F3
41fiedler's myocarditis10.2F3, VWF
42apocrine adenoma10.2F2, F3
43leydig cell tumor10.1F8, VWF
44pancreatic solid pseudopapillary carcinoma10.1F2, F7
45psychosexual disorder10.1F2, VWF
46ischemic heart disease10.1F2, VWF
47focal epilepsy10.1F2, F3
48congenital nystagmus10.1F2, F3, F9
49dentinogenesis imperfecta10.1F2, F3
50hepatic fibrosis renal cysts mental retardation10.1F3, F5

Graphical network of the top 20 diseases related to Factor Xi Deficiency, Autosomal Recessive:



Diseases related to factor xi deficiency, autosomal recessive

Symptoms for Factor Xi Deficiency, Autosomal Recessive

About this section


Clinical features from OMIM:

612416

Human phenotypes related to Factor Xi Deficiency, Autosomal Recessive:

 63
id Description HPO Frequency HPO Source Accession
1 abnormal bleeding63 HP:0001892
2 reduced factor xi activity63 HP:0001929
3 prolonged partial thromboplastin time63 HP:0003645

Drugs & Therapeutics for Factor Xi Deficiency, Autosomal Recessive

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Drugs for Factor Xi Deficiency, Autosomal Recessive (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 191)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AcetylcholineapprovedPhase 477651-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
2
Acamprosateapproved, investigationalPhase 43977337-76-971158
Synonyms:
3-(Acetylamino)propanesulphonic acid
3-Acetamido-1-propanesulfonic acid
3-acetamidopropane-1-sulfonic acid
77337-70-3 (mono-hydrochloride salt)
77337-71-4 (mono-potassium salt)
77337-72-5 (mono-lithium salt)
77337-73-6 (calcium[2:1] salt)
77337-74-7 (magnesium[2:1] salt)
77337-76-9
AC1L2FNA
AC1Q1L6O
AC1Q6X8K
AOTA
AR-1H6082
Acamprosate
Acamprosate (INN)
Acamprosate 6473
Acamprosate [INN:BAN]
Acamprosato
Acamprosato [INN-Spanish]
Acamprosatum
 
Acamprosatum [INN-Latin]
Aotal
Aotal (TN)
C5H11NO4S
CHEBI:51041
CID71158
Campral
D07058
DB00659
EINECS 278-667-4
HSDB 7358
LS-120940
N-Acetylhomotaurine
N-acetyl homotaurine
UNII-N4K14YGM3J
acamprosate
acamprosate (Campral)
acamprostate
calcium acetyl homotaurinate
calcium acetylhomotaurinate
calcium acetylhomotaurine
sodium acetylhomotaurine
3
EthanolapprovedPhase 4204364-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
4Peripheral Nervous System AgentsPhase 4, Phase 122776
5Pharmaceutical SolutionsPhase 4, Phase 1, Phase 27793
6abobotulinumtoxinAPhase 4626
7onabotulinumtoxinAPhase 4626
8Anti-Infective AgentsPhase 4, Phase 3, Phase 2, Phase 121402
9Neurotransmitter AgentsPhase 4, Phase 1, Phase 217734
10Botulinum ToxinsPhase 4669
11Cholinergic AgentsPhase 43846
12Botulinum Toxins, Type APhase 4630
13incobotulinumtoxinAPhase 4635
14Neuromuscular AgentsPhase 41129
15ArtemisininsPhase 4, Phase 3286
16
PiperaquinePhase 41094085-31-85079497
Synonyms:
1,3-bis(1-(7-chloro-4'-quinolyl)-4'-piperazinyl)propane
1,3-bis(4-(7'-chloro-4'-quinoline)-1-piperazine)
4,4'-(propane-1,3-diyldipiperazine-4,1-diyl)bis(7-chloroquinoline)
4085-31-8
5-23-03-00072 (Beilstein Handbook Reference)
7-chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline
83764-65-2
AC1L3UA1
AC1Q3T7B
AR-1F7471
 
BRN 0905079
C29H32Cl2N6
CHEMBL303933
CID122262
FT-0082661
I06-1673
LS-142194
Piperaquinoline
Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro- (9CI)
Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro-)
ST51053186
piperaquine
17
DihydroartemisininPhase 49471939-50-96918483
Synonyms:
(3R,5aS,6R,8aS,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10-ol
1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol(Dihydroartemisinin)
71939-50-9
81496-81-3
AC-2067
AC1L32PY
AC1L9UV6
Ambotz71939-50-9
Artenimol
Artenimol (INN)
CHEBI:207229
CHEMBL25164
CID107770
 
CID456410
CID6918483
Cotecxin
D07362
D3793
Dihydroartemisinin
Dihydroartemisinine
Dihydroqinghaosu
Dihydroquinghaosu
Dihydroquinghoasu
GNF-PF-5634
JAV-110
LS-64240
VM3352
[3R-(3.alpha.,5a.beta.,6.beta.,8a.beta.,9.alpha.,10.alpha.,12.beta.,12aR*)]-Decahydro-10-hydroxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4.3-j]-1,2-benzodioxepin
18ArtemisininePhase 4, Phase 3286
19Antiprotozoal AgentsPhase 4, Phase 31986
20AntimalarialsPhase 4, Phase 31216
21Antiparasitic AgentsPhase 4, Phase 32127
22
LumefantrineapprovedPhase 314582186-77-46437380
Synonyms:
(+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha((dibutylamino)methyl)fluorene-4-methanol
(+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha-((dibutylamino)methyl)fluorene-4-methanol
(±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol
120583-69-9
2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol
2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol
2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol
2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol
82186-77-4
AC-4542
AC1O5NKD
Benflumetol
Bio-0132
C30H32Cl3NO
 
CHEBI:156095
CHEMBL38827
CID6437380
Coartem
D03821
DB06708
HSDB 7210
I14-7746
LS-177674
Lumefantrine
Lumefantrine (INN)
Lumefantrine [INN:BAN]
MolPort-006-394-826
NCGC00167490-01
UNII-F38R0JR742
dl-Benflumelol
23
ArtesunateapprovedPhase 318188495-63-06917864, 5464098
Synonyms:
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-ol, hydrogen succinate
112346-66-4
182824-33-5
252637-87-9
4-Oxo-4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano(4,3-j)-1,2-benzodioxepin-10-yl hydrogen butanedioate
4-oxo-4-{[(3r,5as,6r,8as,9r,10r,12r,12ar)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy}butanoic acid
4-oxo-4-{[(5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy}butanoic acid
83507-69-1
88495-63-0
91487-94-4
AC1L23PW
AC1L2XWW
AC1L4FU0
AC1Q5VRV
AKOS004119951
AS
Ambap88495-63-0
Arinate
Arsumax
Arsumax (TN)
Artesunate
Artesunate (USAN)
Artesunate (superseded RN)
Artesunato
Artesunato [INN-Spanish]
Artesunatum
Artesunatum [INN-Latin]
Artesunic acid
Artsuna
BB_NC-1045
Butanedioic acid, mono((3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-yl) ester
Butanedioic acid, mono(decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-yl) ester
C19H28O8
CHEMBL218601
CHEMBL258608
CID105031
CID11520210
CID11988384
CID156252
 
CID5464098
CID65664
CID6917864
CID9821433
CPD000466336
D02482
Dihydroartemisinine-12-alpha-succinate
Dihydroqinghaosusuccinate
Dihydroqinghasu hemsuccinate
FT-0082543
HMS2051I14
HMS2090L16
HSDB 7458
I06-0204
LS-177760
LS-187735
MLS000759445
MLS001424053
MolPort-001-732-325
MolPort-006-392-384
NCI60_039350
NSC712571
Nuartez
Plasmotrim
Plasmotrin
Qinghaozhi
Quinghaosu reduced succinate ester
S2265_Selleck
SAM001246628
SM 804
SMR000466336
STK801911
Succinyl dihydroartemisinin
UNII-60W3249T9M
WR 256283
WR-256283
artesunato
artesunatum
artesunic acid
butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester
dihydroqinghasu hemsuccinate
24
Miconazoleapproved, investigational, vet_approvedPhase 3362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
25
SulfadoxineapprovedPhase 31282447-57-617134
Synonyms:
2447-57-6
4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
4-Sulfanilamido-5,6-dimethoxypyrimidine
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
4-amino-N-[5,6-bis(methyloxy)pyrimidin-4-yl]benzenesulfonamide
46810_RIEDEL
5-25-13-00306 (Beilstein Handbook Reference)
6-(4-Aminobenzenesulfonamido)-4,5-dimethoxypyrimidine
AB00514044
AC-11921
AC1L29DT
AC1Q46GG
Ambap2447-57-6
BPBio1_001286
BRD-K55250441-001-03-1
BRN 0625453
BSPBio_001168
C07630
CAS-2447-57-6
CHEBI:9329
CHEMBL1539
CID17134
D00580
DB01299
EINECS 219-504-9
Fanasil
Fanzil
HMS1571K10
HMS2090P07
HMS2094C19
I09-0529
LS-31247
MLS002154150
MolPort-003-850-341
N'-(5,6-Dimethoxy-4-pyrimidyl)sulfanilamide
N(sup 1)-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
 
N1-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
NCGC00016612-01
NCGC00016612-02
Orthosulfin
Prestwick0_001094
Prestwick1_001094
Prestwick2_001094
Prestwick3_001094
Ro 4-4393
Ro-4-4393
S2511_Selleck
S7821_SIGMA
SMR000857259
SPBio_003054
SULFADOXINE
Sanasil: Sulfadoxine: Sulformetoxin
Solfadossina
Solfadossina [DCIT]
Sulfadoxin
Sulfadoxina
Sulfadoxina [INN-Spanish]
Sulfadoxine
Sulfadoxine (JAN/USP/INN)
Sulfadoxine [USAN:INN:BAN:JAN]
Sulfadoxinum
Sulfadoxinum [INN-Latin]
Sulformethoxine
Sulformetoxine
Sulforthomidine
Sulphadoxine
Sulphormethoxine
Sulphormetoxin
Sulphorthodimethoxine
UNII-88463U4SM5
WR 4073
WR 4873
ZINC00002094
26
CisplatinapprovedPhase 3, Phase 2269015663-27-184093, 441203, 2767
Synonyms:
(SP-4-1)-diamminedichloridoplatinum
(SP-4-1)-diamminedichloroplatinum
(SP-4-2)-diamminedichloridoplatinum
(SP-4-2)-diamminedichloroplatinum
Abiplatin
Biocisplatinum
Briplatin
CACP
CDDP
CHEBI:35852
CID441203
CPD0-1392
CPDC
CPDD
Carboquone
Cis Pt II
Cis-DDP
Cis-Diaminedichloroplatinum
Cis-Diamminedichloroplatinum
Cismaplat
Cisplatine
Cisplatino
Cisplatinum
Cisplatyl
Citoplationo
DB00515
DDP
DDPT
Diamminedichloroplatinum
 
EU-0100918
Lederplatin
Neoplatin
Peyrone's chloride
Peyrone's salt
Plastin
Platamine
Platiblastin
Platidiam
Platinex
Platinol
Platinol-AQ
Platinoxan
Platinum Ammine Chloride
Platinum Ammonium Chloride
Platinum Diamine Dichloride
Randa
Trans-DDP
Trans-Diaminedichloroplatinum
Trans-Diamminedichloroplatinum
Trans-Dichlorodiammine Platinum
Trans-Platinumdiammine Dichloride
cis-DDP
cis-Diamminedichloroplatinum
cis-Dichlorodiammineplatinum(II)
cis-[PtCl2(NH3)2]
cis-diamminedichloridoplatinum(II)
cis-diamminedichloroplatinum(II)
nchembio773-comp1
trans-diamminedichloridoplatinum(II)
27
Pyrimethamineapproved, vet_approvedPhase 315258-14-04993
Synonyms:
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
46706_FLUKA
46706_RIEDEL
4753 R.P.
4753 r.p
5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE
5-(4-CHLOROPHENYL)-6-ETHYL-2,4-PYRIMIDINEDIAMINE
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidi nediamine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
5-(4-chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
5-(p-chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-[4-Chlorophenyl]-6-ethyl-2,4-pyrimidinediamine
58-14-0
AB00052084
AC-7879
AC1L1JDI
AI3-25005
AZT + Pyrimethamine combination
Aventis Brand of Pyrimethamine
BIDD:GT0149
BIDD:PXR0173
BPBio1_000147
BRD-K88429204-001-05-4
BRN 0219864
BSPBio_000133
BSPBio_003282
BW 50-63
BW 5063
C07391
C12H13ClN4
CAS-58-14-0
CCRIS 546
CD
CHEBI:8673
CHEMBL36
CID4993
CP6
CPD000058714
CRL-8131 & Pyrimethamine
CRL-8142 & Pyrimethamine
Chloridin
Chloridine
Chloridyn
D00488
D011739
DB00205
Darachlor
Daraclor
Darapram
Daraprim
Daraprim (TN)
Daraprime
Daraprin
Diaminopyritamin
Disulone
DivK1c_000652
EINECS 200-364-2
EXR-101
Erbaprelina
Ethylpyrimidine
Fansidar
Fansidar (Pyrimethamine/Sulfadoxine)
Glaxo Wellcome Brand of Pyrimethamine
GlaxoSmithKline Brand of Pyrimethamine
HMS1568G15
HMS1920N12
HMS2092E13
HMS502A14
IDI1_000652
KBio1_000652
KBio2_001386
KBio2_003954
 
KBio2_006522
KBio3_002502
KBioGR_001007
KBioSS_001386
Khloridin
L000713
LS-238
Lactoferrin B & Pyrimethamine
Lactoferrin H & Pyrimethamine
MCB-3837
MLS000028606
MLS001148621
MLS002454446
MLS002701881
Malacid
Malocid
Malocide
Maloprim
MolPort-001-783-655
NCGC00016256-01
NCGC00016256-02
NCGC00023188-03
NCGC00023188-04
NCGC00023188-05
NCGC00023188-06
NCGC00023188-07
NCI-C01683
NCI60_002604
NCIOpen2_008313
NINDS_000652
NSC 3061
NSC-3061
NSC3061
Oxaquin
Pirimecidan
Pirimetamin
Pirimetamina
Pirimetamina [INN-Spanish]
Pirimetamina [Spanish]
Prestwick0_000037
Prestwick1_000037
Prestwick2_000037
Prestwick3_000037
Prestwick_504
Primethamine
Pyremethamine
Pyrimethamin
Pyrimethamine (JAN/USP/INN)
Pyrimethamine (Pyr)
Pyrimethamine Hcl
Pyrimethamine [USAN:INN:BAN:JAN]
Pyrimethaminum
Pyrimethaminum [INN-Latin]
RP 4753
S2006_Selleck
SAM002554921
SMR000058714
SPBio_000672
SPBio_002054
SPECTRUM1500520
Spectrum2_000886
Spectrum3_001701
Spectrum4_000494
Spectrum5_001447
Spectrum_000906
TCMDC-123831
TCMDC-125860
Tindurin
Tindurine
Tinduring
UNII-Z3614QOX8W
WLN: T6N CNJ BZ DZ ER DG& F2
WR 2978
Wellcome Brand of Pyrimethamine
ZINC00057464
m alocid
nchembio.215-comp13
nchembio.87-comp22
pyrimethamine
28
ArtemetherapprovedPhase 314571963-77-4119380, 68911
Synonyms:
( )-alpha-Artemether
(1R,4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin
(3alpha,5abeta,6beta,8abeta,9alpha,10beta,12beta,12aR*)-isomer of artemether
(3r,5as,6r,8as,9r,10r,12r,12ar)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
(5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
.beta.-Artemether
.beta.-Dihydroartemisinin methyl ether
.beta.-Methylether of 11-epi-dihydroartemisinin
10-Methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
159573-83-8
3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-tri
71939-51-0
71963-77-4
74784-06-8
80286-56-2
93787-85-0
AC1L2APD
AC1L2XO8
AC1L9SH2
AC1L9UV0
AC1MI2ZX
AC1Q6Z74
AC1Q6Z7V
AR-1A4424
Arteannuin ether
Artemetero
Artemetero [INN-Spanish]
Artemether
Artemether (INN)
Artemether [INN]
Artemetheri
Artemetherum
Artemetherum [INN-Latin]
Artemisininelactol methyl ether
Artemos
Artenam
Artesaph
Artesian
Artimist
Artmether
BRN 5948416
C16H26O5
CHEBI:195280
 
CHEMBL411864
CHEMBL512315
CID10266705
CID104888
CID3062122
CID456408
CID500199
CID6483308
CID6712286
CID68911
CID9796294
CID9796295
CPD000469218
D02483
DB06697
Dihydroartemisinin methyl ether
Dihydroqinghaosu methyl ether
Dihydroquinghaosu methyl ether
Falcidol
Gvither
HMS2052L09
HSDB 7456
I06-0205
KST-1A8041
LS-176935
LS-64237
MLS001424249
Malartem
Methyl-dihydroartemisinine
NCI60_022891
NSC 665970
NSC665970
O-Methyldihydroartemisinine
Paluther
S2264_Selleck
SAM001246799
SM 224
SM 229
SM-224
SMR000469218
UNII-C7D6T3H22J
alpha-Artemether
alpha-Dihydroartemisinin methyl ether
artemether, (3R-(3alpha,5abeta,6beta,8abeta,9alpha,10alpha,12beta,12aR*))-isomer
artemether[inn]
beta-Artemether
beta-Dihydroartemisinin methyl ether
rither
29
AmodiaquineapprovedPhase 39786-42-02165
Synonyms:
2aou
4-((7-Chloro-4-quinolinyl)amino)-2-((diethylamino)methyl)phenol
4-((7-Chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresol
4-(7-Chloro-quinolin-4-ylamino)-2-diethylaminomethyl-phenol
4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL
4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]phenol
4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol
5-22-10-00283 (Beilstein Handbook Reference)
7-Chloro-4-(3-diethylaminomethyl-4-hydroxyanilino)
7-Chloro-4-(3-diethylaminomethyl-4-hydroxyanilino)quinoline
7-Chloro-4-(3-diethylaminomethyl-4-hydroxyphenylamino)quinoline
86-42-0
AC-13295
AC1L1D2F
AKOS000538864
AMODIAQUINE, FLAVOQUINE
Amodiachin
Amodiachinum
Amodiaquin
Amodiaquina
Amodiaquina [INN-Spanish]
Amodiaquine
Amodiaquine (USAN/INN)
Amodiaquine USP24
Amodiaquine [USAN:INN:BAN]
Amodiaquine hydrochloride
Amodiaquine, ring-closed
Amodiaquinum
Amodiaquinum [INN-Latin]
BAS 00327385
BPBio1_000306
BRN 0300962
BSPBio_000278
Basoquin
Bio-0471
C07626
C20H22ClN3O
CAM-AQ 1
CAM-AQ1
CAM-AQI
 
CCRIS 8486
CHEBI:2674
CHEMBL682
CID2165
CPD-10889
CQA
Cam-AQ1
Camochin
Camoquin
Camoquin HCL
Camoquinal
Camoquine
D02922
DB00613
EINECS 201-669-3
Flavoquin
Flavoquine
HSDB 7457
LS-55353
MLS001304065
Miaquin
MolPort-001-924-563
NSC 13453
NSC13453
Oprea1_019229
Prestwick0_000309
Prestwick1_000309
Prestwick2_000309
Prestwick3_000309
Quinoline, 7-chloro-4-[[3-[(diethylamino)methyl]-4-hydroxyphenyl]amino]-|
S. N. 10751
SMR000718769
SN 10,751
SN 10751
SPBio_002497
Sunoquine
UNII-220236ED28
WR-002977
amodiaquine
amodiaquine hydrochloride
o-Cresol, 4-[(7-chloro-4-quinolyl)amino]-.alpha.-(diethylamino)- (6CI,7CI,8CI)
||SN 10,751
30
Bevacizumabapproved, investigationalPhase 2, Phase 31968216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
31
CetuximabapprovedPhase 3, Phase 1, Phase 2737205923-56-456842117, 2333
Synonyms:
205923-56-4
Anti EGFR
Cetuximab
Cetuximab (USAN/INN)
Cetuximab (genetical recombination)
Cetuximab (genetical recombination) (JAN)
 
Cetuximabum
Cétuximab
D03455
Erbitux
Erbitux (TN)
IMC-C225
Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer
cetuximab
32
FlutamideapprovedPhase 36413311-84-73397
Synonyms:
.alpha.,.alpha.,.alpha.-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide
13311-84-7
1A Brand of Flutamide
2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide
2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propionamide
337962-98-8
37209-54-4
4'-Nitro-3'-(trifluoromethyl)isobutyranilide
4'-Nitro-3'-trifluoromethylisobutyramilide
4'-Nitro-3'-trifluoromethylisobutyranilide
4-Nitro-3-(trifluoromethyl)isobutyranilide
AB00052188
AC-10517
AC1L1FUE
AKOS001025465
Alphapharm Brand of Flutamide
Apimid
Apo Flutamide
Apo-Flutamide
ApoFlutamide
Apogepha Brand of Flutamide
Apotex Brand of Flutamide
Azupharma Brand of Flutamide
BPBio1_000087
BRD-K28307902-001-05-0
BRN 2157663
BSPBio_000079
BSPBio_003122
C07653
C11H11F3N2O3
CAS-13311-84-7
CCRIS 7246
CHEBI:5132
CHEMBL806
CID3397
CPD000058187
Cebatrol
Cebatrol, veterinary
Chephasaar Brand of Flutamide
Chimax
Chiron Brand of Flutamide
Ciclum Brand of Flutamide
Cytamid
D005485
D00586
DB00499
DivK1c_000459
Drogenil
EINECS 236-341-9
ETHINYL ESTRADIOL)
EU-0100557
Essex Brand of Flutamide
Eulexin
Eulexin (TN)
Eulexin, Flutamin, Drogenil,Flutamide
Eulexine
F 9397
F0663
F9397_SIGMA
FTA
Fluken
Flulem
Flumid
Fluta 1A Pharma
Fluta GRY
Fluta cell
Fluta-GRY
Fluta-cell
FlutaGRY
Flutacell
Flutamid
Flutamida
Flutamida [INN-Spanish]
Flutamide
Flutamide (JAN/USP/INN)
Flutamide (pubertal study)
Flutamide USP25
Flutamide [USAN:BAN:INN]
Flutamidum
Flutamidum [INN-Latin]
Flutamin
Flutandrona
Flutaplex
Flutexin
Fugerel
Gry Brand of Flutamide
HMS1568D21
HMS1921O16
HMS2090I18
HMS2092O14
HMS501G21
Ham's F-12 medium
Hexal Brand of Flutamide
 
I01-2470
IDI1_000459
Inibsa Brand of Flutamide
Ipsen Brand of Flutamide
Juta Brand of Flutamide
KBio1_000459
KBio2_001690
KBio2_004258
KBio2_006826
KBio3_002342
KBioGR_001377
KBioSS_001690
Kendrick Brand of Flutamide
LS-2105
Lemery Brand of Flutamide
Lopac-F-9397
Lopac0_000557
METHOXYCHLOR
MLS000069634
MLS001065596
MolPort-001-771-894
NCGC00015452-01
NCGC00015452-02
NCGC00015452-04
NCGC00015452-12
NCGC00091460-01
NCGC00091460-02
NCGC00091460-03
NCGC00091460-04
NCGC00091460-05
NCGC00091460-06
NCGC00091460-07
NCGC00091460-08
NCGC00091460-09
NFBA
NINDS_000459
NK-601
NSC 215876
NSC147834
NSC215876
Niftholide
Niftolid
Niftolide
Novo Flutamide
Novo-Flutamide
NovoFlutamide
Novopharm Brand of Flutamide
Odyne
Oncosal
PMS Flutamide
PMS-Flutamide
PUBERTAL FLUTAMIDE STUDY (PUBERTAL STUDIES OF VINCLOZOLIN
Pharmascience Brand of Flutamide
Prasfarma Brand of Flutamide
Prestwick0_000180
Prestwick1_000180
Prestwick2_000180
Prestwick3_000180
Prestwick_228
Prostacur
Prostandril
Prostica
Prostogenat
Q Pharm Brand of Flutamide
Q-Pharm Brand of Flutamide
S1908_Selleck
SAM002264612
SCH13521
SMR000058187
SPBio_000982
SPBio_002000
SPECTRUM1500995
ST058409
Sch 13521
Sch-13521
Schering Brand of Flutamide
Schering Plough Brand of Flutamide
Schering-Plough Brand of Flutamide
Spectrum2_001201
Spectrum3_001421
Spectrum4_000829
Spectrum5_001450
Spectrum_001210
TAD Brand of Flutamide
Tedec Meiji Brand of Flutamide
Testotard
UNII-76W6J0943E
ZINC03812944
alpha,alpha,alpha-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide
cell pharm Brand of Flutamide
esparma Brand of Flutamide
flutamide
m-Propionotoluidide, alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro- (8CI)
m-propionotoluidide,alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro
niftolid
33
GoserelinapprovedPhase 322965807-02-547725, 5311128
Synonyms:
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
AC1NSK1T
CID5311128
Goserelin
Goserelin acetate
 
HMS2089D16
HS-2015
ICI-118630
MolPort-006-823-831
ZD-9393
Zoladex
goserelin
34
BicalutamideapprovedPhase 317090357-06-556069, 2375
Synonyms:
(+-)-4'-Cyano-alpha,alpha,alpha-trifluoro-3-((p-fluorophenyl)sulfonyl)-2-methyl-m-lactotoluidide
4'-cyano-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methyl-3'-(trifluoromethyl)propionanilide
90357-06-5
AC-4232
AC1L1DJE
Astra brand of bicalutamide
AstraZeneca brand of bicalutamide
BRN 5364666
Bicalutamide (JAN/USP/INN)
Bicalutamide [USAN:INN:BAN]
C053541
C08160
C18H14F4N2O4S
CHEMBL409
CID2375
CPD000466329
Casodex
Casodex (TN)
Casodex, Cosudex, Calutide, Kalumid, Bicalutamide
Cosudex
D00961
DB01128
FT-0080576
 
HMS2051B13
HMS2089N12
I06-0475
I06-0480
ICI 176334
ICI-176334
KS-1161
LS-119125
MLS000759437
MLS001424047
MolPort-003-845-034
MolPort-006-808-679
N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methylpropanamide
NCGC00167977-01
NCGC00167977-02
NSC722665
Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-,
Raffolutil
S1190_Selleck
SAM001246612
SMR000466329
TL8005814
Zeneca brand of bicalutamide
bicalutamide
propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-,(+-)
35
Leuprolideapproved, investigationalPhase 329353714-56-03911, 657181
Synonyms:
(D-Leu(6),des-gly-NH2(10),pro-ethylamide(9))-gonadotropin-releasing hormone
5-oxoPro-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-ProNHC2H5 dihydrate
5-oxoprolylhistidyltryptophylseryltyrosylleucylleucyl-n5-(diaminomethylidene)ornithyl-n-ethylprolinamide
AC1L1GZK
AC1L9B44
AC1Q5OPO
AR-1G9354
C07612
CID3911
CID441410
D00989
D08113
Enantone
Enantone (TN)
I04-0109
L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide
L001094
 
L002030
Leuprolide
Leuprolide acetate
Leuprolide acetate (USAN)
Leuprorelin
Leuprorelin (INN)
Leuprorelin acetate (JAN)
Leuprorelina
Leuproreline
Leuprorelinum
Lupron (TN)
N-[1-[[1-[[1-[[1-[[1-[[1-[[5-(diaminomethylideneamino)-1-[2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
NSC377526
NSC746847
PGlu-his-trp-ser-tyr-D-leu-leu-arg-pro-NHC2H5
PGlu-his-trp-ser-tyr-D-leu-leu-arg-pro-nhet
acetic acid
leuprolide
36
BuserelinapprovedPhase 33257982-77-1
Synonyms:
(Des-Gly10,D-Ser(tBu)6,Pro-NHEt9)-LHRH
 
D-Ser(Tbu)6EA10LHRH
Etilamide
Tiloryth
37
Prednisoneapproved, vet_approvedPhase 3135953-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
38
Folic Acidapproved, nutraceutical, vet_approvedPhase 3, Phase 2427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
39
Docetaxelapproved, investigational, Approved May 1996Phase 31918114977-28-5148124, 9877265
Synonyms:
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (aR,bS)-b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxybenzenepropanoate
(2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
01885_FLUKA
114977-28-5
4-(Acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
4-(acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
AC-383
AC1L3WHJ
ANX-514
BIND-014
C11231
CHEBI:4672
CHEMBL92
CID148124
D07866
DB01248
Docetaxel
Docetaxel (INN)
Docetaxel anhydrous
Docetaxel, Trihydrate
EmDOC
 
HMS2089K08
InChI=1/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,5
MolPort-003-847-005
N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel
N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol
N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel
N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol
N-debenzoyl-N-Boc-10-deacetyl taxol
NSC-628503
PSMA-targeted docetaxel nanoparticle
RP-56976
SDP-014
TXL
Taxotere
Taxotere (TN)
Taxotere(R)
XRP-6976L
docetaxel
docetaxel 114977-28-5
nchembio.188-comp8
nchembio.2007.34-comp7
nchembio.573-comp11
nchembio853-comp8
40Renal AgentsPhase 3, Phase 2, Early Phase 1732
41Central Nervous System DepressantsPhase 312806
42Anti-Inflammatory AgentsPhase 310355
43Folic Acid AntagonistsPhase 32200
44Antimitotic AgentsPhase 3, Phase 25498
45Antifungal AgentsPhase 33615
46AnthelminticsPhase 3431
47AnestheticsPhase 39001
48Artemether-lumefantrine combinationPhase 3138
49Amodiaquine, artesunate drug combinationPhase 39
50VaccinesPhase 36428

Interventional clinical trials:

(show top 50)    (show all 86)
idNameStatusNCT IDPhase
1Efficacy Study of Botox for DepressionUnknown statusNCT01556971Phase 4
2Acamprosate in Alcoholics With Comorbid Anxiety or DepressionCompletedNCT00330174Phase 4
3Pharmacokinetics of Dihydroartemisinin-Piperaquine in the Treatment of Uncomplicated Malaria in Children in Burkina FasoCompletedNCT00845533Phase 4
4Longitudinal Antimalarial Combinations in UgandaCompletedNCT00123552Phase 3
5Randomized Controlled Trial of Enhanced Pharmacy Care in Older Veteran OutpatientsCompletedNCT00122122Phase 3
6A Study With SAGE-547 for Super-Refractory Status EpilepticusRecruitingNCT02477618Phase 3
7Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an MF59-Adjuvanted Quadrivalent Influenza Vaccine Compared to Non-influenza Vaccine Comparator in Adults ≥ 65 Years of AgeRecruitingNCT02587221Phase 3
8Artisan Aphakia Lens for the Correction of Aphakia (Secondary) in AdultsRecruitingNCT01547429Phase 3
9Artisan Aphakia Lens for the Correction of Aphakia in ChildrenRecruitingNCT01547442Phase 3
10Anti-VEGF vs. Prompt Vitrectomy for VH From PDRRecruitingNCT02858076Phase 2, Phase 3
11Anti-VEGF Treatment for Prevention of PDR/DMERecruitingNCT02634333Phase 3
12Treatment for CI-DME in Eyes With Very Good VA StudyRecruitingNCT01909791Phase 3
13Vest Prevention of Early Sudden Death Trial and VEST RegistryRecruitingNCT01446965Phase 3
14Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With Stage III or Stage IV Head and Neck CancerActive, not recruitingNCT00265941Phase 3
15Hormone Therapy and Radiation Therapy or Hormone Therapy and Radiation Therapy Followed by Docetaxel and Prednisone in Treating Patients With Localized Prostate CancerActive, not recruitingNCT00288080Phase 3
16Fluorescent Cholangiography vs White Light for Bile Ducts IdentificationNot yet recruitingNCT02702843Phase 3
17A Phase 2/3 Trial of the the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINALNot yet recruitingNCT03019185Phase 2, Phase 3
18Palifermin in Lessening Oral Mucositis in Patients Undergoing Radiation Therapy and Chemotherapy for Locally Advanced Head and Neck CancerTerminatedNCT00360971Phase 3
19The Effect of Single Dose D-Cycloserine on Cognitive Outcome in Moderate Traumatic Brain Injury (TBI) PatientsUnknown statusNCT01343862Phase 2
20Caphosol for the Reduction of Mucositis in Patients Receiving Radiation Therapy for Head and Neck CancerUnknown statusNCT00901732Phase 1, Phase 2
21UAB 0718 - Phase II Trial to Assess Target Oral Therapy as Adjuvant Chemoprevention in High-Risk Head and Neck CancerCompletedNCT00570232Phase 2
22A Trial of Erlotinib + Radiotherapy for Cutaneous Squamous Cell CarcinomaCompletedNCT00369512Phase 2
23Effects of Black Cohosh on Menopausal Hot FlashesCompletedNCT00010712Phase 2
24Acupuncture to Improve Quality of Life in Patients With Advanced CancerCompletedNCT00070967Phase 2
25Chemotherapy, Surgery, and Radiation Therapy in Treating Patients With Gastric CancerCompletedNCT00003298Phase 2
26Pilot Study to Assess Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-dose Combination in Treatment Experienced Subjects With Hepatitis C Virus (HCV) Genotype 1 - HIV Co-infectionCompletedNCT02125500Phase 2
27Crux Biomedical IVC Filter - Evaluation of the Crux Inferior Vena Cava Filter System (Retrieve)CompletedNCT00605332Phase 2
28Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing SurgeryRecruitingNCT02855086Phase 1, Phase 2
29Cetuximab-IRDye 800CW and Intraoperative Imaging in Finding Pancreatic Cancer in Patients Undergoing SurgeryRecruitingNCT02736578Phase 2
30A Multi-Center Study Evaluating KTE-C19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic LeukemiaRecruitingNCT02625480Phase 1, Phase 2
31Short Duration Therapy of Acute Hepatitis C Genotypes 1 or 4 in HIV-infected PatientsNot yet recruitingNCT02886624Phase 2
32Symptom Burden in Head and Neck CancerTerminatedNCT01219673Phase 1, Phase 2
33Safety Study of Adenovirus/PNP Coupled With Fludarabine Phosphate to Treat Solid TumorsCompletedNCT01310179Phase 1
34The Effects of Antihistamines on Pre-Pulse InhibitionCompletedNCT01537471Phase 1
35Cetuximab IRDye800 Study as an Optical Imaging Agent to Detect Cancer During Surgical ProceduresRecruitingNCT01987375Phase 1
36Phase I Panitumumab IRDye800 Optical Imaging StudyRecruitingNCT02415881Phase 1
37Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute LeukemiaRecruitingNCT02446964Phase 1
38A Pilot Study of Deep Brain Stimulation to the Lateral Habenulae in Treatment-Resistant DepressionRecruitingNCT01798407Phase 1
39A Phase 1 Study Evaluating CB-5083 in Subjects With Advanced Solid TumorsRecruitingNCT02243917Phase 1
40Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing CholangitisRecruitingNCT01088607Phase 1
41Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to TreatmentTerminatedNCT00800150Phase 1
42A Single and Low Dose of Recombinant Factor VIIa in Patients With Severe Factor XI Deficiency Undergoing SurgeryUnknown statusNCT01538160
43The Impact of Dosimeter on Measurement of Airway Responsiveness to MethacholineCompletedNCT00145990
44DeVilbiss AutoAdjust With SmartFlex Comparative StudyCompletedNCT01203956
45Post-traumatic Stress Disorder (PTSD), Addiction, and Virtual RealityCompletedNCT01186315
46Developing Computer Based Treatments for AddictionCompletedNCT00586534
47DBT Compared to I/GDC for the Treatment of Opiate Addiction in Emotionally Dysregulated Patients. - 1CompletedNCT00218595
48Evaluating a Novel Method of Generalizing Emotion RegulationCompletedNCT01653548
49Trial of Low and High Intensity Strategies to Maintain BP ControlCompletedNCT00760552
50Women's Use of Alternative Medicine: A Multiethnic StudyCompletedNCT00067249

Search NIH Clinical Center for Factor Xi Deficiency, Autosomal Recessive


Cochrane evidence based reviews: factor xi deficiency

Genetic Tests for Factor Xi Deficiency, Autosomal Recessive

About this section

Genetic tests related to Factor Xi Deficiency, Autosomal Recessive:

id Genetic test Affiliating Genes
1 Hereditary Factor Xi Deficiency Disease26
2 Factor Xi Deficiency24 F11

Anatomical Context for Factor Xi Deficiency, Autosomal Recessive

About this section

MalaCards organs/tissues related to Factor Xi Deficiency, Autosomal Recessive:

35
Brain, Liver, Endothelial, Prostate, Breast, Eye, Lymph node

Animal Models for Factor Xi Deficiency, Autosomal Recessive or affiliated genes

About this section

MGI Mouse Phenotypes related to Factor Xi Deficiency, Autosomal Recessive:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.7F11, F2, F3, F8, F9, VWF
2MP:00053878.6F11, F2, F3, F8, F9, VWF
3MP:00053857.8F11, F2, F3, F5, F7, F9
4MP:00053767.2F11, F2, F3, F5, F7, F8
5MP:00107686.4F11, F2, F3, F5, F7, F8

Publications for Factor Xi Deficiency, Autosomal Recessive

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Variations for Factor Xi Deficiency, Autosomal Recessive

About this section

UniProtKB/Swiss-Prot genetic disease variations for Factor Xi Deficiency, Autosomal Recessive:

69 (show all 58)
id Symbol AA change Variation ID SNP ID
1F11p.Phe301LeuVAR_006622rs121965064
2F11p.Asp34HisVAR_012085rs281875267
3F11p.Trp246CysVAR_012086rs281875279
4F11p.Ser266AsnVAR_012087rs145168351
5F11p.Leu320ProVAR_012088rs281875268
6F11p.Thr322IleVAR_012089rs281875269
7F11p.Arg326CysVAR_012090rs28934608
8F11p.Glu341LysVAR_012091rs281875270
9F11p.Thr404AsnVAR_012092rs121965067
10F11p.Ala430ValVAR_012093rs121965068
11F11p.Phe460ValVAR_012094rs121965065
12F11p.Thr493IleVAR_012095
13F11p.Ser594ArgVAR_012096rs28934609
14F11p.Cys46PheVAR_054894rs281875271
15F11p.Cys56ArgVAR_054895rs121965069
16F11p.Lys101ArgVAR_054896rs281875272
17F11p.Tyr151CysVAR_054897rs281875273
18F11p.Cys255TyrVAR_054898rs281875277
19F11p.Gly263GluVAR_054899rs281875274
20F11p.Lys270IleVAR_054900rs121965070
21F11p.Gly418ValVAR_054901rs121965071
22F11p.Tyr511HisVAR_054902rs281875278
23F11p.Pro538LeuVAR_054903rs139695003
24F11p.Glu565LysVAR_054904rs281875275
25F11p.Trp587SerVAR_054905rs121965072
26F11p.Ile618SerVAR_054906rs281875276
27F11p.Gly32ArgVAR_067929rs281875259
28F11p.Ala43ThrVAR_067930rs281875264
29F11p.Thr51IleVAR_067931rs281875252
30F11p.Thr51ProVAR_067932rs281875243
31F11p.His53GlnVAR_067933rs281875261
32F11p.Ala63ValVAR_067934rs281875244
33F11p.Cys140TyrVAR_067935rs281875256
34F11p.Asp222TyrVAR_067936rs281875245
35F11p.Arg228GlnVAR_067937rs281875246
36F11p.Phe241LeuVAR_067938rs281875265
37F11p.Arg252ThrVAR_067939rs281875260
38F11p.Ser276CysVAR_067940rs281875247
39F11p.Gly277AspVAR_067941rs281875248
40F11p.Glu315LysVAR_067942rs281875257
41F11p.Thr331IleVAR_067943rs281875253
42F11p.Leu360ProVAR_067944rs281875254
43F11p.Trp401ArgVAR_067945rs281875262
44F11p.Val403MetVAR_067946rs281875266
45F11p.Ile454LysVAR_067947rs281875241
46F11p.Ile481SerVAR_067948rs281875242
47F11p.Ser503ProVAR_067949rs140068026
48F11p.Asp506GlyVAR_067950rs281875258
49F11p.Cys514PheVAR_067951rs281875249
50F11p.Asp526GluVAR_067952rs281875263
51F11p.Ser575LeuVAR_067953rs281875250
52F11p.Glu597LysVAR_067954rs281875251
53F11p.Tyr608HisVAR_067955rs281875255
54F11p.Phe30SerVAR_076515
55F11p.Ala109ThrVAR_076516rs768474112
56F11p.Asp216AsnVAR_076517
57F11p.Glu543LysVAR_076518rs142952627
58F11p.His552ArgVAR_076519rs369935706

Clinvar genetic disease variations for Factor Xi Deficiency, Autosomal Recessive:

5 (show all 50)
id Gene Variation Type Significance SNP ID Assembly Location
1F11NM_000128.3(F11): c.1716+1G> ASNVPathogenicrs373297713GRCh37Chr 4, 187208978: 187208978
2F11NM_000128.3(F11): c.403G> T (p.Glu135Ter)SNVPathogenicrs121965063GRCh37Chr 4, 187195347: 187195347
3F11NM_000128.3(F11): c.901T> C (p.Phe301Leu)SNVPathogenicrs121965064GRCh37Chr 4, 187201412: 187201412
4F11F11, IVS9AS, A-G, -2SNVPathogenicChr na, -1: -1
5F11F11, IVS5DS, G-C, +5SNVPathogenicChr na, -1: -1
6F11NM_000128.3(F11): c.1378T> G (p.Phe460Val)SNVPathogenicrs121965065GRCh37Chr 4, 187206865: 187206865
7F11NM_000128.3(F11): c.438C> A (p.Cys146Ter)SNVPathogenicrs121965066GRCh37Chr 4, 187195382: 187195382
8F11NM_000128.3(F11): c.1211C> A (p.Thr404Asn)SNVPathogenicrs121965067GRCh37Chr 4, 187205321: 187205321
9F11NM_000128.3(F11): c.976C> T (p.Arg326Cys)SNVPathogenicrs28934608GRCh37Chr 4, 187201487: 187201487
10F11NM_000128.3(F11): c.1289C> T (p.Ala430Val)SNVPathogenicrs121965068GRCh37Chr 4, 187205399: 187205399
11F11NM_000128.3(F11): c.1782C> A (p.Ser594Arg)SNVPathogenicrs28934609GRCh37Chr 4, 187209672: 187209672
12F11NM_000128.3(F11): c.166T> C (p.Cys56Arg)SNVLikely pathogenic, Pathogenicrs121965069GRCh37Chr 4, 187192873: 187192873
13F11NM_000128.3(F11): c.1253G> T (p.Gly418Val)SNVLikely pathogenic, Pathogenicrs121965071GRCh37Chr 4, 187205363: 187205363
14F11NM_000128.3(F11): c.1760G> C (p.Trp587Ser)SNVPathogenicrs121965072GRCh37Chr 4, 187209650: 187209650
15F11F11, DELdeletionPathogenicChr na, -1: -1
16F11NM_000128.3(F11): c.1075delA (p.Ile359Tyrfs)deletionLikely pathogenicrs786204429GRCh38Chr 4, 186280520: 186280520
17F11NM_000128.3(F11): c.961_962delTG (p.Cys321Hisfs)deletionLikely pathogenicrs786204449GRCh37Chr 4, 187201472: 187201473
18F11NM_000128.3(F11): c.1186C> T (p.Arg396Cys)SNVLikely pathogenicrs771896253GRCh37Chr 4, 187205296: 187205296
19F11NM_000128.3(F11): c.682C> T (p.Arg228Ter)SNVLikely pathogenicrs752907087GRCh37Chr 4, 187197471: 187197471
20F11NM_000128.3(F11): c.325G> A (p.Ala109Thr)SNVLikely pathogenicrs768474112GRCh37Chr 4, 187194331: 187194331
21F11NM_000128.3(F11): c.1556G> A (p.Trp519Ter)SNVLikely pathogenicrs201007090GRCh37Chr 4, 187207644: 187207644
22F11NM_000128.3(F11): c.400C> T (p.Gln134Ter)SNVLikely pathogenic, Pathogenicrs756908183GRCh37Chr 4, 187195344: 187195344
23F11NM_000128.3(F11): c.408C> A (p.Cys136Ter)SNVLikely pathogenicrs143648758GRCh38Chr 4, 186274198: 186274198
24F11NM_000128.3(F11): c.751C> T (p.Gln251Ter)SNVLikely pathogenicrs754087775GRCh37Chr 4, 187197540: 187197540
25F11NM_000128.3(F11): c.730C> T (p.Gln244Ter)SNVLikely pathogenicrs747702749GRCh37Chr 4, 187197519: 187197519
26F11NM_000128.3(F11): c.1107C> A (p.Tyr369Ter)SNVLikely pathogenicrs773905328GRCh38Chr 4, 186280552: 186280552
27F11NM_000128.3(F11): c.67C> T (p.Gln23Ter)SNVLikely pathogenicrs768409400GRCh37Chr 4, 187192774: 187192774
28F11NM_000128.3(F11): c.908delG (p.Gly303Glufs)deletionLikely pathogenicrs786204722GRCh38Chr 4, 186280265: 186280265
29F11NM_000128.3(F11): c.1313C> A (p.Ser438Ter)SNVLikely pathogenicrs786204724GRCh37Chr 4, 187206800: 187206800
30F11NM_000128.3(F11): c.1613C> T (p.Pro538Leu)SNVLikely pathogenicrs139695003GRCh38Chr 4, 186287720: 186287720
31F11NM_000128.3(F11): c.1432G> A (p.Gly478Arg)SNVPathogenicrs542967227GRCh37Chr 4, 187206919: 187206919
32F11NM_000128.3(F11): c.1288G> A (p.Ala430Thr)SNVPathogenicrs753909969GRCh37Chr 4, 187205398: 187205398
33F11NM_000128.3: c.219G> ASNVLikely pathogenicChr na, -1: -1
34F11NM_000128.3: c.1789G> TSNVLikely pathogenicChr na, -1: -1
35F11NM_000128.3: c.964_965delACdeletionLikely pathogenicChr na, -1: -1
36F11NM_000128.3: c.1481-1G> TSNVLikely pathogenicChr na, -1: -1
37F11NM_000128.3: c.25_28delCATTdeletionLikely pathogenicChr na, -1: -1
38F11NM_000128.3: c.486-2A> GSNVLikely pathogenicChr na, -1: -1
39F11NM_000128.3: c.218+1G> ASNVLikely pathogenicChr na, -1: -1
40F11NM_000128.3: c.1560dupGduplicationLikely pathogenicChr na, -1: -1
41F11NM_000128.3: c.1390C> TSNVLikely pathogenicChr na, -1: -1
42F11NM_000128.3: c.1778C> TSNVLikely pathogenicChr na, -1: -1
43F11NM_000128.3: c.596-7_600del12deletionLikely pathogenicChr na, -1: -1
44F11NM_000128.3: c.291delGdeletionLikely pathogenicChr na, -1: -1
45F11NM_000128.3: c.1676_1682del7deletionLikely pathogenicChr na, -1: -1
46F11NM_000128.3: c.1305-1G> ASNVLikely pathogenicChr na, -1: -1
47F11NM_000128.3: c.326-1G> ASNVPathogenicChr na, -1: -1
48F11NM_000128.3: c.1247G> ASNVLikely pathogenicChr na, -1: -1
49F11NM_000128.3: c.1232_1235delCTCAdeletionLikely pathogenicChr na, -1: -1
50F11NM_000128.3(F11): c.1693G> A (p.Glu565Lys)SNVLikely pathogenicrs281875275GRCh37Chr 4, 187208954: 187208954

Expression for genes affiliated with Factor Xi Deficiency, Autosomal Recessive

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Search GEO for disease gene expression data for Factor Xi Deficiency, Autosomal Recessive.

Pathways for genes affiliated with Factor Xi Deficiency, Autosomal Recessive

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Pathways related to Factor Xi Deficiency, Autosomal Recessive according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5F2, VWF
2
Show member pathways
9.0F2, F7, F9
39.0F2, F7, F9
4
Show member pathways
6.9F11, F2, F3, F5, F7, F8
5
Show member pathways
6.4F11, F2, F3, F5, F7, F8
6
Show member pathways
6.4F11, F2, F3, F5, F7, F8

GO Terms for genes affiliated with Factor Xi Deficiency, Autosomal Recessive

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Cellular components related to Factor Xi Deficiency, Autosomal Recessive according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granuleGO:00310919.9F5, VWF
2ER to Golgi transport vesicleGO:00301349.7F5, F8
3Golgi lumenGO:00057969.6F2, F7, F9
4extracellular matrixGO:00310129.5F2, F3, VWF
5platelet alpha granule lumenGO:00310939.3F5, F8, VWF
6endoplasmic reticulum lumenGO:00057888.1F2, F5, F7, F8, F9
7extracellular spaceGO:00056157.0F11, F2, F3, F5, F7, F8
8extracellular regionGO:00055767.0F11, F2, F5, F7, F8, F9
9plasma membraneGO:00058866.9F11, F2, F3, F5, F7, F8

Biological processes related to Factor Xi Deficiency, Autosomal Recessive according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1regulation of blood coagulationGO:003019310.2F11, F2
2positive regulation of platelet-derived growth factor receptor signaling pathwayGO:001064110.1F3, F7
3positive regulation of positive chemotaxisGO:005092710.0F3, F7
4acute-phase responseGO:00069539.9F2, F8
5blood coagulation, extrinsic pathwayGO:00075989.7F3, F7, F9
6peptidyl-glutamic acid carboxylationGO:00171879.6F2, F7, F9
7signal peptide processingGO:00064659.5F2, F7, F9
8COPII vesicle coatingGO:00482089.5F5, F8
9positive regulation of blood coagulationGO:00301949.3F2, F7
10platelet degranulationGO:00025769.0F5, F8, VWF
11blood coagulation, intrinsic pathwayGO:00075978.8F11, F2, F8, F9, VWF
12platelet activationGO:00301688.3F2, F5, F8, VWF
13ER to Golgi vesicle-mediated transportGO:00068888.0F2, F5, F7, F8, F9
14blood coagulationGO:00075966.4F11, F2, F3, F5, F7, F8

Molecular functions related to Factor Xi Deficiency, Autosomal Recessive according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endopeptidase activityGO:00041759.6F7, F9
2copper ion bindingGO:00055079.0F5, F8
3serine-type endopeptidase activityGO:00042526.9F11, F2, F3, F5, F7, F8

Sources for Factor Xi Deficiency, Autosomal Recessive

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet