MCID: FHR002

Fahr's Syndrome malady

Summaries for Fahr's Syndrome

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43NINDS, 32MalaCards
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NINDS:43 Fahr's Syndrome is a rare, genetically dominant, inherited neurological disorder characterized by abnormal deposits of calcium in areas of the brain that control movement, including the basal ganglia and the cerebral cortex. Symptoms of the disorder may include deterioration of motor function, dementia, seizures, headache, (poorly articulated speech), (stiffness of the limbs) and spastic paralysis, eye impairments, and (involuntary, writhing movements). Fahr's Syndrome can also include symptoms characteristic of Parkinson's disease such as tremors, muscle rigidity, a mask-like facial appearance, shuffling gait, and a "pill-rolling" motion of the fingers. These symptoms generally occur later in the development of the disease. More common symptoms include dystonia (disordered muscle tone) and chorea (involuntary, rapid, jerky movements). Age of onset is typically in the 40s or 50s, although it can occur at any time in childhood or adolescence.

MalaCards: Fahr's Syndrome An important gene associated with Fahr's Syndrome is SNCA (synuclein, alpha (non A4 component of amyloid precursor)). Affiliated tissues include eye, brain and cortex.

Aliases & Classifications for Fahr's Syndrome

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43NINDS, 60UMLS
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Aliases & Descriptions:

fahr's syndrome 43 60


Related Diseases for Fahr's Syndrome

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Clinical Features for Fahr's Syndrome

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Drugs & Therapeutics for Fahr's Syndrome

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Fahr's Syndrome

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Anatomical Context for Fahr's Syndrome

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32MalaCards
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MalaCards organs/tissues related to Fahr's Syndrome:

32
Eye, Brain, Cortex

Animal Models for Fahr's Syndrome or affiliated genes

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Publications for Fahr's Syndrome

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Genetic Variations for Fahr's Syndrome

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Expression for genes affiliated with Fahr's Syndrome

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Fahr's Syndrome

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Pathways for genes affiliated with Fahr's Syndrome

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Compounds for genes affiliated with Fahr's Syndrome

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GO Terms for genes affiliated with Fahr's Syndrome

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Products for genes affiliated with Fahr's Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Fahr's Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet