Fainting malady

MedlinePlus: If you've ever fainted, you are not alone - at least one third of people faint sometime in their lives. fainting is a temporary loss of consciousness. you lose muscle control at the same time, and may fall down. most people recover quickly and completely. fainting usually happens when your blood pressure drops suddenly, causing a decrease in blood flow to your brain. this is more common in older people. some causes of fainting include heat or dehydration emotional distress standing up too quickly certain medicines drop in blood sugar heart problems fainting is usually nothing to worry about, but it can sometimes be a sign of a serious problem. if you faint, it's important to see your health care provider and find out why it happened.²³

MalaCards: Fainting is related to jervell-lange nielsen syndrome and long qt syndrome. An important gene associated with Fainting is SCIMP (SLP adaptor and CSK interacting membrane protein), and among its related pathways are PKA Signaling and cAMP Pathway. The compounds sodium and cyclic amp have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and pituitary, and related mouse phenotypes are homeostasis/metabolism and cardiovascular system.

NINDS: Syncope is a medical term used to describe a temporary loss of consciousness due to the sudden decline of blood flow to the brain. Syncope is commonly called fainting or ?passing out.? If an individual is about to faint, he or she will feel dizzy, lightheaded, or nauseous and their field of vision may ?white out? or ?black out.?³¹

Wikipedia: Syncope (pron.: /ˈsɪŋkəpi/ SING-kə-pee), the medical term for fainting, is precisely defined as a...⁴⁴ more...

fainting 31 23

Diseases related to fainting by text searches and GeneDecks gene sharing:

(show top 50)    (show all 91)

id	Related Disease	Score	Top Affiliating Genes
1	jervell-lange nielsen syndrome	29.6	CACNA1C, SCN5A, KCNH2
2	long qt syndrome	28.3	CACNA1C, ADRB1, HCN4, GPD1L, SCN5A, SCN1B
3	syncope	28.0	ADRB1, HCN4, ACHE, GNAS, CHKB, SCN5A
4	brugada syndrome	27.9	CACNA1C, HCN4, CACNB2, GPD1L, SCN3B, SCN5A
5	catecholaminergic polymorphic ventricular tachycardia	27.4	ADRB1, GNAI2, CHKB, SCN5A, KCNH2
6	atrial fibrillation	25.3	SCN5A, SCN1B, KCNH2, KCNE3, SERPINE1, VWF
7	primary hyperoxaluria	13.7	SLC26A10, SLC26A11, SLC26A6, SLC26A1
8	atelosteogenesis	13.6	SLC26A5, SLC26A2, SLC26A1
9	chloride diarrhea	13.6	SLC26A2, SLC26A3, SLC26A4
10	congenital chloride diarrhea	13.6	SLC26A2, SLC26A3, SLC26A4
11	achondrogenesis	13.6	SLC26A5, SLC26A2, SLC26A1
12	congenital stationary night blindness	13.5	GNAZ, GNAT1, GNAO1, GNAI1
13	pendred syndrome	13.4	SLC26A5, SLC26A2, SLC26A3, SLC26A4
14	brugada syndrome 2	13.4	GPD1L, SCN5A
15	pseudohypoparathyroidism	13.3	GNAS, GNAL, GNA15, GNA11
16	hypokalemia	13.2	SLC26A3, SLC26A4, KCNH2, KCNE3
17	pseudocholinesterase deficiency	13.2	ACHE, BCHE
18	long qt syndrome 2	13.2	SCN5A, KCNH2
19	conduction disease	13.2	CACNB2, SCN3B, SCN5A, SCN1B
20	hypokalemic periodic paralysis	13.1	CACNA1C, CHKB, KCNE3
21	congenital hypothyroidism	13.0	SLC26A4, POU1F1, ACHE, GNAS
22	sudden infant death syndrome	13.0	GNAS, GPD1L, SCN3B, SCN5A, SCN1B, KCNH2
23	diastrophic dysplasia	13.0	SLC26A5, SLC26A2, SLC26A7, SLC26A9, SLC26A3, SLC26A11
24	night blindness	12.8	CRP, GNAZ, GNAT1, GNAO1, GNAI3, GNAI1
25	right bundle branch block	12.7	CACNA1C, HCN4, CACNB2, GPD1L, SCN3B, SCN5A
26	congenital heart defect	12.6	ADRB1, CYSLTR2, F8, CHKB, SCN5A, KCNH2
27	alpha 1-antitrypsin deficiency	12.5	SCN5A, KCNH2, CHKB
28	cholera	12.5	CXCR4, ACHE, GNAZ, GNAS, GNAO1, GNAI1
29	chorea	12.5	ACHE, CRP, GNAQ, GNA14
30	central retinal vein occlusion	12.4	F8, SERPINE1, VWF
31	bleeding diathesis due to gnaq deficiency	12.3	GNAS, F8, SERPINE1, VWF
32	thrombotic thrombocytopenic purpura, acquired	12.2	F8, SERPINE1, VWF
33	trypanosomiasis	12.1	GNAS, GNAQ, GNAO1, GNAL, GNAI3, GNAI2
34	ischemic heart disease	12.1	ADRB1, CRP, CYSLTR2, GNAI1, CHKB, KCNH2
35	major depressive disorder	12.1	CACNA1C, GNAT2, GNAL, GNAI3, F8, SERPINE1
36	retinal artery occlusion	12.0	CRP, F8, SERPINE1
37	hypertrophic cardiomyopathy	11.9	CACNA1C, HCN4, CACNB2, GNAS, GNAI1, CHKB
38	ventricular fibrillation	11.8	GPD1L, CHKB, SCN3B, SCN5A, SCN1B, KCNH2
39	pertussis	11.8	ADRB1, CXCR4, CYSLTR2, BLZF1, FPR1, GNA11
40	retinal vein occlusion	11.8	CRP, F8, SERPINE1, VWF
41	diarrhea	11.7	SLC26A2, SLC26A3, SLC26A4, ACHE, CRP, GNAS
42	hellp syndrome	11.7	CRP, F8, BCHE, SERPINE1, VWF
43	factor v leiden thrombophilia	11.6	CRP, F8, SERPINE1, VWF
44	disseminated intravascular coagulation	11.6	CRP, F8, BCHE, SERPINE1, VWF
45	chagas disease	11.6	GNAO1, GNAQ, GNAS, CXCR4, ADRB1, GNAL
46	hyperthyroidism	11.4	ADRB1, VWF, SERPINE1, CHKB, GNAS, CRP
47	sinusitis	11.3	ADRB1, HCN4, ACHE, CRP, CYSLTR2, SCN5A
48	tuberculosis	11.2	SLC26A11, SLC26A3, SLC26A9, SLC26A10, SLC26A7, SLC26A2
49	hyperhomocysteinemia	11.2	CRP, F8, BCHE, SERPINE1, VWF
50	thrombosis	11.1	CRP, GNAQ, GNA15, GNA14, GNA11, F8

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to fainting:

²²

MGI Mouse Phenotypes related to fainting:

²⁵

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism phenotype	MP:0005376	INF	CACNA1C, GNAI3, BCHE, GNAI2, GNAI1, GNA13
2	cardiovascular system phenotype	MP:0005385	INF	CRP, GNAT2, GNA12, GNA11, LAMA1,
3	mortality/aging	MP:0010768	INF	PDE2A, FPR1, VWF, , SEMA3C, SERPINE1
4	muscle phenotype	MP:0005369	INF	GNAQ, GNAS, ACHE, , CXCR4, ADRB1
5	nervous system phenotype	MP:0003631	INF	ABCC1, CHKB, NF2, , LAMA1, GNAZ
6	growth/size phenotype	MP:0005378	INF	CXCR4, POU1F1, ACHE, ADRB1, GNAL, GNAO1

Articles related to fainting:

(show all 11)

id	Title	Authors	Year	Affiliating Genes
1	Pituitary adenomas that show a faint GH-immunoreactiv ity but lack fibrous body: Pit-1 adenoma with endocrinologically low activity. (20111911)	Yoneda A.... Kudo E.	2010	POU1F1
2	Low creatine kinase is associated with a high populat ion incidence of fainting. (19468786)	Brewster L.M.... Wieling W.	2009	CHKB
3	G-protein coupled receptor signaling in myocardium: not for the faint of heart. (17557938)	Kang M.... Walker J.W.	2007	CYSLTR2
4	The Arg389Gly beta1-adrenergic receptor gene polymorphism and susceptibility to faint during head-up tilt test. (17463065)	Marquez M.F.... Vargas-Alarcon G.	2007	ADRB1
5	Fainting induces an acute increase in the concentration of plasma factor VIII and von Willebrand factor. (12801845)	Casonato A.... Girolami A.	2003	VWF, F8
6	The role of cell adhesion molecules in Drosophila heart morphogenesis: faint sausage, shotgun/DE-cadherin, and laminin A are required for discrete stages in heart development. (10075841)	Haag T.A.... Hartenstein V.	1999	LAMA1
7	Expression patterns of the JEM-1 gene in normal and tumor cells: ubiquity contrasting with a faint, but retinoid-induced, mRNA expression in promyelocytic NB4 cells. (9823948)	Tong J.H.... Lanotte M.	1998	BLZF1
8	The molecular genetics of the long QT syndrome: genes causing fainting and sudden death. (9509262)	Vincent G.M.	1998	KCNH2
9	Faint and positive amniotic fluid acetylcholinesterase with a normal sonogram. (8885764)	Brown C.L.... Evans M.I.	1996	ACHE
10	Scanning gel densitometry of amniotic fluid acetylcholinesterase and butyrylcholinesterase: quantification of 'faint-positive' bands in fetal malformations. (7647148)	Dupont M.... Demaille J.	1995	BCHE, ACHE
11	The association between 'faint-positive' amniotic fluid acetylcholinesterase and fetal malformations. (8140072)	Sadovsky Y.... Golbus M.S.	1993	ACHE

Genes related to fainting according to GeneCards:

(show top 50)    (show all 72)

id	Symbol	Description	Score	GeneCards Section Context
1	SCIMP	SLP adaptor and CSK interacting membrane protein	11.0	Expressions
2	KCNF1	potassium voltage-gated channel, subfamily F, member 1	11.0	Orthologs
3	KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	11.0	Orthologs
4	KCNV1	potassium channel, subfamily V, member 1	11.0	Orthologs
5	HMGN2P46	high mobility group nucleosomal binding domain 2 pseudogene 46	11.0	Expressions
6	SLC26A1	solute carrier family 26 (sulfate transporter), member 1	11.0	Orthologs
7	SLC26A10	solute carrier family 26, member 10	11.0	Orthologs
8	APOBR	apolipoprotein B receptor	11.0	Expressions
9	GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	11.0	Orthologs
10	KCNS1	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1	11.0	Orthologs
11	ISYNA1	inositol-3-phosphate synthase 1	11.0	Orthologs
12	KCNG1	potassium voltage-gated channel, subfamily G, member 1	11.0	Orthologs
13	KCNV2	potassium channel, subfamily V, member 2	11.0	Orthologs
14	KCNG4	potassium voltage-gated channel, subfamily G, member 4	11.0	Orthologs
15	CREG2	cellular repressor of E1A-stimulated genes 2	11.0	Expressions
16	GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide	11.0	Orthologs
17	C12orf75	chromosome 12 open reading frame 75	11.0	Expressions
18	BFAR	bifunctional apoptosis regulator	11.0	Expressions
19	GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	11.0	Orthologs
20	SLC26A6	solute carrier family 26, member 6	11.0	Orthologs
21	KCNG2	potassium voltage-gated channel, subfamily G, member 2	11.0	Orthologs
22	KCNG3	potassium voltage-gated channel, subfamily G, member 3	11.0	Orthologs
23	SLC26A9	solute carrier family 26, member 9	11.0	Orthologs
24	SLC26A11	solute carrier family 26, member 11	11.0	Orthologs
25	GNA13	guanine nucleotide binding protein (G protein), alpha 13	11.0	Orthologs
26	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	11.0	Orthologs
27	GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	11.0	Orthologs
28	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	11.0	Orthologs
29	GNAT3	guanine nucleotide binding protein, alpha transducing 3	11.0	Orthologs
30	SLC26A3	solute carrier family 26, member 3	11.0	Orthologs
31	SLC26A2	solute carrier family 26 (sulfate transporter), member 2	11.0	Orthologs
32	POU1F1	POU class 1 homeobox 1	11.0	Publications
33	WNT7B	wingless-type MMTV integration site family, member 7B	11.0	Expressions
34	LLGL2	lethal giant larvae homolog 2 (Drosophila)	11.0	Proteins
35	KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3	11.0	Orthologs
36	CYSLTR2	cysteinyl leukotriene receptor 2	11.0	Publications
37	EED	embryonic ectoderm development	11.0	Orthologs
38	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	11.0	Orthologs
39	SLC26A8	solute carrier family 26, member 8	11.0	Orthologs
40	PDE2A	phosphodiesterase 2A, cGMP-stimulated	11.0	Publications
41	FPR1	formyl peptide receptor 1	11.0	Publications
42	BLZF1	basic leucine zipper nuclear factor 1	11.0	Publications
43	ANKRD30A	ankyrin repeat domain 30A	11.0	Expressions
44	GNA12	guanine nucleotide binding protein (G protein) alpha 12	11.0	Orthologs
45	ADRB1	adrenoceptor beta 1	11.0	Publications
46	SLC26A4	solute carrier family 26, member 4	11.0	Orthologs
47	GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	11.0	Orthologs
48	SLC26A5	solute carrier family 26, member 5 (prestin)	11.0	Orthologs
49	SLC26A7	solute carrier family 26, member 7	11.0	Orthologs
50	MYOCD	myocardin	11.0	Expressions

Pathways related to fainting according to GeneDecks:

(show top 50)    (show all 134)

id	Pathway	Score	Top Affiliating Genes
1	PKA Signaling36	INF	GNAL, GNAO1, GNAT1, GNAT2, GNAZ, GNG4
2	cAMP Pathway36	INF	CACNA1C, ADRB1, CRP, , GNG4, GNAI2
3	Antiarrhythmic Pathway, Pharmacodynamics34	INF	CACNA1C, ADRB1, , , ,
4	Activation of cAMP-Dependent PKA36	INF	PDE2A, KCNV2, KCNV1, , ,
5	GHRH Signaling36	INF	GNA11, , , , GNA12, GNA13
6	Dopamine-DARPP32 Feedback onto cAMP Pathway36	INF	KCNH2, KCNG4, KCNG2, KCNF1, KCNS3, CACNA1C
7	Voltage gated Potassium channels38	10.1	KCNV1, KCNS2, KCNS1, KCNG3, KCNG1, KCNV2
8	Thrombin signalling through proteinase activated receptors (PARs)38	9.7	GNA15, GNA14, GNA13, GNA12, GNA11, GNAQ
9	Visual Cycle in Retinal Rods36	9.4	GNA11, GNA12, GNA13, GNA14, GNA15, GNAI1
10	Long-term depression20	9.4	GNAI2, GNA13, GNAI1, GNAI3, GNAO1, GNAQ
11	Inhibitory action of Lipoxin A4 on PDGF, EGF and LTD4 signaling41	9.4	CYSLTR2, GNAZ, GNAQ, GNAO1, GNAI3, GNAI2
12	Actin-Based Motility by Rho Family GTPases36	9.3	GNA11, GNA12, GNA13, GNA15, GNAI3, GNAO1
13	Platelet Aggregation Inhibitor Pathway, Pharmacodynamics34	9.2	GNA13, GNAI1, GNAI2, GNAS, GNA15, GNA12
14	G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins10	9.1	GNA11, GNA12, GNA13, GNAI1, GNAI2, GNAI3
15	G-protein signaling_Regulation of p38 and JNK signaling mediated by G-proteins41	9.1	GNA12, GNA13, GNAI1, GNAI3, GNAO1, GNAQ
16	Endothelin-1 Signaling Pathway36	9.1	GNAL, GNAO1, GNAT1, GNAT2, GNAZ, GNAI2
17	Development G-Proteins mediated regulation MARK-ERK signaling10	9.0	GNAO1, GNAQ, GNAS, GNAZ, GNG4, GNA11
18	Development_G-Proteins mediated regulation MARK-ERK signaling41	9.0	GNAZ, GNAS, GNAQ, GNAO1, GNAI3, GNAI2
19	Thrombin Signaling36	8.9	GNAT1, GNAT2, GNAZ, GNG4, GNA11, GNA12
20	Huntingtons Disease Pathway36	8.9	GNAZ, GNG4, GNAT2, GNAT1, GNAO1, GNAL
21	Actin Nucleation and Branching36	8.9	GNA11, GNA12, GNA13, GNA14, GNA15, GNAI1
22	fMLP Pathway36	8.9	GNA11, GNG4, GNAZ, GNAT2, GNAT1, GNAO1
23	Factors Promoting Cardiogenesis in Vertebrates36	8.8	GNA11, GNA12, GNG4, GNAI1, GNA15, GNA14
24	Actin Nucleation by ARP-WASP Complex36	8.8	GNG4, GNAZ, GNAT2, GNAT1, GNAO1, GNAL
25	AMPK Enzyme Complex Pathway36	8.8	GNA14, GNAO1, GNA15, GNA12, GNA11, GNAI1
26	Chagas disease (American trypanosomiasis)20	8.8	SERPINE1, GNA14, GNA15, GNAI1, GNA11, GNAL
27	Human Embryonic Stem Cell Pluripotency36	8.8	GNAT1, GNAT2, GNAZ, GNG4, WNT7B, GNAO1
28	Relaxin Pathway36	8.8	PDE2A, GNA11, GNA12, GNA13, GNA14, GNA15
29	Hedgehog Signaling in Mammals36	8.8	WNT7B, GNAI2, GNAI3, GNAL, GNAO1, GNAT1
30	ERK5 Signaling36	8.8	GNA15, GNA11, GNA12, GNA13, GNA14, GNAI1
31	WNT Signaling36	8.7	GNAZ, GNAI3, GNAT2, GNAT1, GNAL, GNG4
32	Activation of PKC through GPCR36	8.7	GNAI1, GNAT2, GNAI3, GNA15, PDE2A, GNA14
33	Cell adhesion Integrin inside-out signaling10	8.7	GNAZ, GNAQ, GNAO1, GNAI3, GNAI1, GNA12
34	Cell adhesion_Integrin inside-out signaling41	8.6	GNAI2, GNAI3, GNAO1, GNAQ, GNAZ, GNG4
35	CDK5 Pathway36	8.6	GNA13, GNA14, GNA15, GNAI1, GNAI2, GNAI3
36	CXCR4 Pathway36	8.6	GNA15, CXCR4, GNG4, GNAI2, GNAI1, GNA14
37	Estrogen Pathway36	8.5	GNA15, GNA14, GNA13, GNAT1, GNA12, GNAI1
38	EphB-EphrinB Signaling36	8.4	GNA11, CXCR4, GNG4, GNAZ, GNA12, GNA13
39	Activation of PKA through GPCR36	7.9	GNA11, GNA12, GNA13, GNA15, GNAI1, GNAI2
40	IP3 Pathway36	INF	GNAZ, GNG4, , CACNA1C, GNAT2, GNAT1
41	Sperm Motility36	INF	GNA13, GNA14, GNA15, GNAI1, GNAI2, GNAI3
42	GnRH Signaling36	INF	GNAO1, GNAL, GNAI3, GNAI2, GNAI1, GNA15
43	Androgen Signaling36	INF	CACNA1C, GNA11, GNA15, , GNG4, GNA13
44	Signaling Involved in Cardiac Hypertrophy36	INF	CACNA1C, GNA11, GNA12, GNA13, GNA14, GNA15
45	G-Beta Gamma Signaling36	INF	GNAI2, GNAI1, GNA15, GNA14, GNA13, GNA12
46	Melatonin Signaling36	INF	GNA12, GNA11, KCNV1, KCNV2, GNA14, GNA13
47	CRHR Pathway36	INF	GNA11, GNA12, GNA13, CACNA1C, , GNA14
48	Sweet Taste Signaling36	INF	KCNV1, GNAL, GNA11, GNA13, PDE2A, CACNA1C
49	CCR5 Pathway in Macrophages36	INF	CACNA1C, , GNG4, GNAL, GNA15, GNA14
50	CREB Pathway36	INF	GNAT1, , GNAI2, GNAI1, GNAI3, GNAL

Compounds related to fainting according to GeneDecks:

(show top 50)    (show all 75)

id	Compound	Score	Top Affiliating Genes
1	sodium32 18	INF	SLC26A7, ADRB1, BLZF1, , SLC26A11, SLC26A4
2	cyclic amp32 18	INF	GNAQ, ADRB1, POU1F1, , CYSLTR2, GNAT3
3	potassium32 9 18 9	INF	, GNAQ, BLZF1, , , KCNH2
4	oxalate32	10.5	SLC26A2, SLC26A5, SLC26A1, SLC26A4
5	nf 02342	10.4	GNAI2, GNAO1, GNAI1, GNAI3
6	iodide32 18	11.4	SLC26A4, SLC26A5, SLC26A2, SLC26A1
7	mastoparan32 42	11.4	GNAI2, GNAO1, GNAI3, GNAI1
8	formate32	10.3	SLC26A1, SLC26A4, SLC26A2, SLC26A5
9	melittin32 42	11.3	GNAI1, GNAI2, GNAS, GNAI3
10	sulfate32 18	11.2	SLC26A4, SLC26A1, SLC26A11, SLC26A3, SLC26A2, SLC26A5
11	pertussis toxin42	10.2	GNAT1, GNAT2, GNAI3, GNAI2, GNAI1, GNAT3
12	bicarbonate32	10.1	SLC26A3, SLC26A1, CHKB, SLC26A5, SLC26A4, SLC26A2
13	tacrine hydrochloride42	10.0	BCHE, ACHE
14	butyrylcholine32	9.9	BCHE, ACHE
15	fasciculin32	9.9	ACHE, BCHE
16	mefloquine32 9 9	11.9	KCNH2, ACHE, BCHE
17	succinylcholine32 9 9	11.9	BCHE, ACHE, CHKB
18	butyrylthiocholine32 9 9	11.8	ACHE, BCHE
19	g-protein antagonist peptide42	9.7	GNA11, GNA12, GNA13, GNA14, GNA15, GNAL
20	physostigmine hemisulfate42	9.6	ACHE, BCHE
21	atenolol32 9 18 9	12.5	KCNH2, ADRB1, SERPINE1, CRP
22	nacl32	9.5	BLZF1, FPR1, SLC26A4, GNAI1, SLC26A3, F8
23	tranexamic acid32 9 9	11.4	F8, SERPINE1, VWF
24	thromboxane a232 18	10.4	GNAI1, GNAQ, F8, VWF, CYSLTR2, GNA13
25	gtp32	9.3	GNAI1, GNAZ, CYSLTR2, ADRB1, GNAS, FPR1
26	guanine32 9 18 9	12.3	VWF, ADRB1, GNAQ, GNAS, GNAL, GNAI1
27	quinapril32 9 9	11.2	CRP, SERPINE1, VWF
28	perindopril32 34 9 9	12.2	BCHE, CRP, SERPINE1, VWF
29	mastoparan x42 32	10.1	GNA15, GNAI1, GNAI2, GNAI3, GNAL, GNAO1
30	isoproterenol32 9 9	11.0	VWF, GNAI1, GNAS, ADRB1, KCNH2, SERPINE1
31	prostacyclin32	8.6	CYSLTR2, GNAI1, CRP, PDE2A, VWF, SERPINE1
32	epinephrine32 9 18 9	11.4	F8, GNAI1, CXCR4, CYSLTR2, ADRB1, ABCC1
33	norepinephrine32 9 18 9	11.2	BCHE, CHKB, F8, GNAI1, GNAS, ADRB1
34	cyclophosphamide32 34 9 9	11.1	CXCR4, CRP, F8, BCHE, SERPINE1, VWF
35	adenylate32	8.0	GNAS, CYSLTR2, CXCR4, ADRB1, CHKB, KCNH2
36	aspirin32 34 18	9.9	F8, CHKB, BCHE, SERPINE1, CYSLTR2, CRP
37	nitric oxide32 9 18 9	10.5	GNAI1, F8, FPR1, MYOCD, SERPINE1, VWF
38	flecainide acetate42	INF	, ,
39	quinidine32 34 9 9	INF	BCHE, KCNH2, , ABCC1
40	calcium32 9 18 9	INF	, , GNAZ, CYSLTR2, KCNH2, GNAT3
41	ralfinamide mesylate42	INF	, ,
42	am 92016 hydrochloride42	INF	KCNS3, KCNG4, KCNG2, KCNF1, , KCNV2
43	alanine32	INF	GNAS, CXCR4, PDE2A, VWF, BLZF1, BCHE
44	dibucaine32 9 9	INF	ACHE, , BCHE
45	qx 314 chloride42	INF	, ,
46	arginine32	INF	CXCR4, PDE2A, VWF, BLZF1, BCHE, KCNH2
47	tetrodotoxin citrate42	INF	, ,
48	chlorine32 18	INF	SLC26A5, SLC26A10, SLC26A9, SLC26A3, SLC26A8, SLC26A7
49	kn-9342	INF	KCNG1, KCNV2, KCNS3, KCNG4, KCNF1,
50	4-aminopyridine32 42	INF	, KCNF1, KCNV1, KCNS1, KCNG1, KCNV2

Cellular components related to fainting according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	voltage-gated potassium channel complex	GO:008076	9.6	KCNG2, KCNG4, KCNH2, KCNS3, KCNV2, KCNG1
2	heterotrimeric G-protein complex	GO:005834	9.3	GNA15, GNAT2, GNG4, GNAS
3	plasma membrane	GO:005886	INF	CACNA1C, CYSLTR2, GNG4, GNAZ, GNAT3, GNAT2
4	voltage-gated sodium channel complex	GO:001518	INF	, ,

Biological processes related to fainting according to GeneDecks:

(show all 23)

id	Name	GO ID	Score	Top Affiliating Genes
1	membrane depolarization involved in regulation of action potential	GO:086010	INF	,
2	negative regulation of synaptic transmission	GO:050805	10.2	GNAI3, BCHE, GNAI2
3	potassium ion transport	GO:006813	10.2	KCNS3, KCNG1, KCNS1, KCNV1, KCNH2, KCNF1
4	sulfate transport	GO:008272	10.2	SLC26A2, SLC26A8, SLC26A7, SLC26A4, SLC26A1, SLC26A11
5	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	GO:007193	10.1	GNAZ, GNAL, GNAI3, GNAI2, GNAI1
6	protein ADP-ribosylation	GO:006471	10.1	GNAQ, GNA14, GNA11, GNA15
7	ion transport	GO:006811	10.1	SLC26A3, SLC26A6, SLC26A1, SLC26A4, SLC26A2, SLC26A7
8	regulation of melanocyte differentiation	GO:045634	10.1	GNAQ, GNA11
9	oxalate transport	GO:019532	9.9	SLC26A8, SLC26A7
10	protein homooligomerization	GO:051260	9.8	KCNV2, VWF, KCNF1, KCNG4, KCNV1, KCNG2
11	transmembrane transport	GO:055085	9.4	ABCC1, SLC26A3, SLC26A2, SLC26A7, SLC26A9, GNAS
12	energy reserve metabolic process	GO:006112	9.2	CACNA1C, GNG4, GNAS, KCNS3, KCNG2
13	GTP catabolic process	GO:006184	9.0	GNAQ, GNA13, GNA14, GNA15, GNAI1, GNAI2
14	G-protein coupled receptor signaling pathway	GO:007186	8.9	CXCR4, GNG4, GNAZ, GNAT2, GNAI2, GNAI1
15	platelet activation	GO:030168	8.4	F8, SERPINE1, GNAI2, GNA12, GNAI3, GNA13
16	blood coagulation	GO:007596	8.1	GNA12, GNA11, GNAI1, GNAS, GNAQ, GNAI3
17	regulation of heart contraction	GO:008016	INF	KCNG2, KCNH2, GNAO1,
18	regulation of heart rate by cardiac conduction	GO:086091	INF	, KCNH2, ,
19	synaptic transmission	GO:007268	INF	, KCNG1, KCNV2, KCNS3, KCNH2, KCNG4
20	sodium ion transmembrane transport	GO:035725	INF	, ,
21	regulation of atrial cardiomyocyte membrane depolarization	GO:060371	INF	, ,
22	membrane depolarization involved in regulation of cardiac muscle cell action potential	GO:086012	INF	, ,
23	regulation of cardiac muscle cell action potential involved in contraction	GO:086002	INF	, ,

Molecular functions related to fainting according to GeneDecks:

(show all 12)

id	Name	GO ID	Score	Top Affiliating Genes
1	voltage-gated potassium channel activity	GO:005249	INF	KCNG1, KCNG3, KCNS2, KCNV1, ,
2	oxalate transmembrane transporter activity	GO:019531	10.2	SLC26A8, SLC26A1, SLC26A7
3	anion:anion antiporter activity	GO:015301	10.1	SLC26A11, SLC26A3, SLC26A9, SLC26A7, SLC26A8
4	delayed rectifier potassium channel activity	GO:005251	10.1	KCNS3, KCNH2, KCNG2, KCNS1
5	sulfate transmembrane transporter activity	GO:015116	10.1	SLC26A7, SLC26A10, SLC26A1, SLC26A4, SLC26A8, SLC26A2
6	secondary active sulfate transmembrane transporter activity	GO:008271	10.0	SLC26A9, SLC26A5, SLC26A3, SLC26A6, SLC26A1, SLC26A4
7	acetylcholinesterase activity	GO:003990	9.9	BCHE, ACHE
8	GTPase activity	GO:003924	9.2	GNAT1, GNAS, GNAQ, GNAI1, GNA15, GNA11
9	GTP binding	GO:005525	8.7	GNAO1, GNAQ, GNAS, GNAT1, GNAT2, GNAT3
10	metal ion binding	GO:046872	7.9	CRP, GNAZ, GNA12, GNA11, GNAT3, GNAT2
11	potassium channel regulator activity	GO:015459	INF	KCNV1, , KCNS3, KCNS1
12	voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential	GO:086006	INF	, ,