Summaries for Fainting

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MedlinePlus:32 Fainting is a temporary loss of consciousness. if you're about to faint, you'll feel dizzy, lightheaded, or nauseous. your field of vision may "white out" or "black out." your skin may be cold and clammy. you lose muscle control at the same time, and may fall down. fainting usually happens when your blood pressure drops suddenly, causing a decrease in blood flow to your brain. it is more common in older people. some causes of fainting include heat or dehydration emotional distress standing up too quickly certain medicines drop in blood sugar heart problems when someone faints, make sure that the airway is clear and check for breathing. the person should stay lying down for 10-15 minutes. most people recover completely. fainting is usually nothing to worry about, but it can sometimes be a sign of a serious problem. if you faint, it's important to see your health care provider and find out why it happened.

MalaCards based summary: Fainting is related to atrial fibrillation and myocardial infarction. An important gene associated with Fainting is CHKB (choline kinase beta), and among its related pathways are Response to elevated platelet cytosolic Ca2+ and Complement and coagulation cascades. The compounds tetramethylpyrazine and abciximab have been mentioned in the context of this disorder. Affiliated tissues include brain, skin and heart, and related mouse phenotype homeostasis/metabolism.

NINDS:42 Syncope is a medical term used to describe a temporary loss of consciousness due to the sudden decline of blood flow to the brain. Syncope is commonly called fainting or ?passing out.? If an individual is about to faint, he or she will feel dizzy, lightheaded, or nauseous and their field of vision may ?white out? or ?black out.?

Wikipedia:63 Syncope (/?s??k?pi/ SING-k?-pee), also known as fainting or passing out, is defined as a short loss of... more...

Aliases & Classifications for Fainting

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Fainting, Aliases & Descriptions:

Name: Fainting 42 32


Related Diseases for Fainting

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Diseases related to Fainting via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 81)
idRelated DiseaseScoreTop Affiliating Genes
1atrial fibrillation30.0CHKB, KCNH2, VWF
2myocardial infarction29.6CHKB, VWF, F8
3syncope10.6
4factor xii deficiency10.4VWF
5long qt syndrome10.3
6postural orthostatic tachycardia syndrome10.3
7factor xi deficiency, autosomal recessive10.3F8
8factor viii deficiency10.3F8
9chronic orthostatic intolerance10.2
10aortic valve disease 210.2
11pulmonary hypertension10.2
12cerebritis10.2
13brugada syndrome10.2
14spinocerebellar ataxia10.1KCNH2, CHKB
15acute myocardial infarction10.1VWF, CHKB
16long qt syndrome 110.1
17multiple system atrophy10.1
18jervell and lange-nielsen syndrome10.1
19catecholaminergic polymorphic ventricular tachycardia10.1
20ectopic pregnancy10.1
21multiple system atrophy with orthostatic hypotension10.1
22compartment syndrome10.1CHKB, F8
23hemarthrosis10.1F8, VWF
24intracranial thrombosis10.1VWF, F8
25hemorrhagic disease10.0VWF, F8
26noonan syndrome 110.0CHKB, KCNH2
27blood platelet disease10.0F8, VWF
28von willebrand's disease10.0F8, VWF
29hemophilia a10.0VWF, F8
30afibrinogenemia10.0VWF, F8
31thrombotic thrombocytopenic purpura, acquired10.0VWF, F8
32bernard-soulier syndrome, type c10.0VWF, F8
33thrombophilia due to activated protein c resistance10.0VWF, F8
34glanzmann thrombasthenia10.0VWF, F8
35antiphospholipid syndrome10.0VWF, F8
36thrombophilia10.0VWF, F8
37hyperhomocysteinemia10.0VWF, F8
38myopathy10.0CHKB, KCNH2
39thrombophilia due to thrombin defect10.0F8, VWF
40non-suppurative otitis media10.0CHKB, F8
41brain disease10.0F8, VWF
42hypersensitivity reaction type ii disease10.0VWF, F8
43congenital heart disease10.0VWF, F8
44thrombocytopenia10.0F8, VWF
45deficiency anemia10.0VWF, CHKB
46hyperinsulinemic hypoglycemia, familial, 79.9
47peters anomaly9.9
48asthma9.9
49osteogenesis imperfecta, type xiii9.9
50syncope, familial vasovagal9.9

Graphical network of the top 20 diseases related to Fainting:



Diseases related to fainting

Symptoms for Fainting

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Drugs & Therapeutics for Fainting

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Drug clinical trials:

Search ClinicalTrials for Fainting

Search NIH Clinical Center for Fainting

Genetic Tests for Fainting

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Anatomical Context for Fainting

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MalaCards organs/tissues related to Fainting:

31
Brain, Skin, Heart, Testes, Whole blood, Skeletal muscle, T cells, Pituitary

Animal Models for Fainting or affiliated genes

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MGI Mouse Phenotypes related to Fainting:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.0F8, CHKB, KCNH2, VWF

Publications for Fainting

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Articles related to Fainting:

(show top 50)    (show all 190)
idTitleAuthorsYear
1
Fainting Starting Parenteral Nutrition. (25853719)
2015
2
Fainting as an unusual presentation of a large inferior vena cava leiomyosarcoma. (24837084)
2014
3
Role of sympathetic nerve activity in the process of fainting. (25309444)
2014
4
Malignant cardioinhibitory vasovagal syncope - an uncommon cardiovascular complication of Roux-en-Y gastric bypass surgery: the fainting syndrome! (23063207)
2013
5
A 40-year-old man with recurrent fainting, hypotension, lower limb edema and oliguria with body weight gain and secondary erythrocytosis. (21948352)
2012
6
Case 2: 'I feel faint': An adolescent with recurrent dizziness and syncope. (23730166)
2012
7
Physiologic strategies to prevent fainting responses during or after whole blood donation. (21645008)
2011
8
Fainting, swooning, and syncope. (22132356)
2011
9
Episode of fainting and tetany after an evaluation technique of the upper cervical region: a case report. (20724209)
2011
10
A 46-year-old woman with chin pain and a fainting spell. (20391493)
2010
11
Fainting with HIV. (20800149)
2010
12
Physiological correlates of applied tension may contribute to reduced fainting during medical procedures. (19730965)
2009
13
Fainting in classical art. (16730508)
2006
14
Blood-injury phobia with and without a history of fainting: disgust sensitivity does not explain the fainting response. (16554401)
2006
15
Evolution and fear-fainting. (16845485)
2006
16
Solving the mysteries of fainting. Why you may be at risk, and how you can protect yourself. (16193559)
2005
17
Fainting freshmen and sinking sophomores: cardiovascular issues of the adolescent. (15273492)
2004
18
Multiple life-threatening fainting episodes: fatal systemic mastocytosis. (14719479)
2003
19
Fainting induces an acute increase in the concentration of plasma factor VIII and von Willebrand factor. (12801845)
2003
20
Fainting in animals. (12955549)
2003
21
Long QT syndrome patients may faint due to neurocardiogenic syncope. (14753633)
2003
22
A fainting mechanic. (12147374)
2002
23
Fainting. When it spells trouble and when it doesn't. (14646918)
2002
24
Ask the doctor. I'm 78 years old. I've known for years that I have a narrowing of the aortic valve of my heart. My doctors are always asking me whether I have chest pain, fainting spells, or any other special symptoms. Until recently, the answer has been no. A few days ago, however, I was washing dishes in my kitchen, and I suddenly felt lightheaded and fell to the ground. I didn't black out, but I almost did. Now my doctor is saying that I should have my aortic valve replaced. Isn't this rather an extreme response to just one spell of lightheadedness? (11269241)
2001
25
Informed consent, and fainting fathers. (11412197)
2001
26
Intellect and somatic health: associations with hypochondriacal concerns, perceived threat and fainting. (11598431)
2001
27
Pacemakers promising for repeated fainting spells. (10198443)
1999
28
Antidepressants for fainting spells. (10445969)
1999
29
Postural hypotension. Faintness upon standing. (10892313)
1999
30
Sudden fainting in an elderly woman. (9793549)
1998
31
Expression patterns of the JEM-1 gene in normal and tumor cells: ubiquity contrasting with a faint, but retinoid-induced, mRNA expression in promyelocytic NB4 cells. (9823948)
1998
32
Variability of near-fainting responses in healthy 6-16-year-old subjects. (9337634)
1997
33
Hospitalization for fainting: high stakes, low yield. (9095018)
1997
34
Fainting precipitated by collapse-firing of venous baroreceptors. (8105220)
1993
35
The Mutilation Questionnaire as a predictor of blood/injury fear and fainting. (2256902)
1990
36
Emotional fainting and the psychophysiologic response to blood and injury: autonomic mechanisms and coping strategies. (3413272)
1988
37
The psychophysiological process of therapy in a case of injury-scene-elicited fainting. (4044863)
1985
38
Fainting and bromocriptine: Danger when motoring. (69848)
1977
39
Letter: Fainting during general anaesthesia in supine dental patients. (4414226)
1974
40
"The Fainting on the John"-syndrome. (5278114)
1971
41
The health questionnaire in general dental practice. 6. Epilepsy and fainting. (5287223)
1971
42
Fainting: a review of its mechanisms and a study in blood donors. (4864338)
1967
43
The common fainting attack: a danger in dental-chair anaesthesia. (5214679)
1965
44
THE COMMON FAINTING ATTACK; A DANGER IN DENTAL-CHAIR ANAESTHESIA. (14319205)
1965
45
FAINTING. (14064413)
1963
46
Post-operative fainting. Brain damage in patients propped up after operation. (13871931)
1962
47
Antidiuretic substances in human urine after haemorrhage, fainting, dehydration and acceleration. (13118534)
1953
48
After-cough fainting as a complication of bronchial asthma. (13076792)
1953
49
Hepatic blood flow and carbohydrate changes in man during fainting. (14898521)
1951
50
Fainting and shock. (20239280)
1947

Variations for Fainting

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Expression for genes affiliated with Fainting

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Search GEO for disease gene expression data for Fainting.

Pathways for genes affiliated with Fainting

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Pathways related to Fainting according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1F8, VWF
2
Show member pathways
Complement Activation, Classical Pathway36
Complement and Coagulation Cascades36
9.1F8, VWF
3
Show member pathways
9.1F8, VWF

Compounds for genes affiliated with Fainting

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Compounds related to Fainting according to GeneCards Suite gene sharing:

(show top 50)    (show all 75)
idCompoundScoreTop Affiliating Genes
1tetramethylpyrazine439.9CHKB, VWF
2abciximab43 1210.8CHKB, VWF
3guanidine43 24 1211.8CHKB, VWF
4saponins439.8CHKB, KCNH2
5clopidogrel43 49 24 1212.8CHKB, VWF
6clarithromycin43 1210.7CHKB, KCNH2
7amiodarone43 49 28 1212.7KCNH2, CHKB
8diltiazem43 28 49 1212.7KCNH2, CHKB
9raloxifene43 49 28 1212.7VWF, CHKB
10chlorpromazine28 43 49 1212.6CHKB, KCNH2
11recombinate439.6F8, VWF
12kogenate439.6F8, VWF
13tributylphosphate439.6F8, VWF
14rfviii439.6F8, VWF
15phenytoin43 49 28 1212.6KCNH2, CHKB
16hydroxyethyl starch439.5F8, VWF
17tranexamic acid43 1210.5VWF, F8
18halothane43 49 28 1212.5KCNH2, CHKB
19ristocetin439.5F8, VWF
20desmopressin43 59 28 1212.5F8, VWF
21guanidine hydrochloride439.4CHKB, VWF
22hirudin439.4F8, VWF
23fluvastatin43 49 28 1212.3CHKB, VWF
24ivig439.3VWF, F8
25warfarin43 49 24 1212.2F8, VWF
26adenylate439.1VWF, KCNH2, CHKB
27latex439.1VWF, CHKB, F8
28prednisolone43 28 1211.0F8, CHKB, VWF
29citrate439.0VWF, CHKB, F8
30agarose439.0F8, CHKB, VWF
31olanzapine43 49 28 24 1213.0CHKB, KCNH2
32aspirin43 49 28 2412.0VWF, CHKB, F8
33epinephrine43 24 1211.0F8, CHKB, VWF
34fibrinogen439.0F8, CHKB, VWF
35norepinephrine43 24 1211.0VWF, CHKB, F8
36testosterone43 59 24 1212.0CHKB, KCNH2, VWF
37cyclosporin a43 28 5911.0F8, CHKB, VWF
38glutamine439.0VWF, CHKB, F8
39lactate439.0VWF, CHKB, F8
40aspartate438.9VWF, CHKB, F8
41heparin43 28 24 1211.9F8, CHKB, VWF
42methionine438.9F8, KCNH2, VWF
43lysine438.9F8, CHKB, KCNH2
44cholesterol43 28 24 1211.7F8, CHKB, VWF
45steroid438.5KCNH2, CHKB, F8
46phospholipid438.4F8, CHKB, KCNH2, VWF
47creatinine438.4VWF, KCNH2, CHKB, F8
48arginine438.4VWF, KCNH2, CHKB, F8
49alanine438.4F8, CHKB, KCNH2, VWF
50calcium43 49 24 1211.2VWF, KCNH2, CHKB, F8

GO Terms for genes affiliated with Fainting

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Cellular components related to Fainting according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:00310939.1F8, VWF

Biological processes related to Fainting according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet activationGO:00301689.1F8, VWF
2blood coagulation, intrinsic pathwayGO:00075979.0F8, VWF
3platelet degranulationGO:00025768.8F8, VWF

Products for genes affiliated with Fainting

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Sources for Fainting

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet