MCID: FNT004
MIFTS: 30

Fainting malady

Summaries for Fainting

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33MedlinePlus, 43NINDS, 63Wikipedia, 32MalaCards
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MedlinePlus:33 Fainting is a temporary loss of consciousness. if you're about to faint, you'll feel dizzy, lightheaded, or nauseous. your field of vision may "white out" or "black out." your skin may be cold and clammy. you lose muscle control at the same time, and may fall down. fainting usually happens when your blood pressure drops suddenly, causing a decrease in blood flow to your brain. it is more common in older people. some causes of fainting include heat or dehydration emotional distress standing up too quickly certain medicines drop in blood sugar heart problems when someone faints, make sure that the airway is clear and check for breathing. the person should stay lying down for 10-15 minutes. most people recover completely. fainting is usually nothing to worry about, but it can sometimes be a sign of a serious problem. if you faint, it's important to see your health care provider and find out why it happened.

MalaCards: Fainting is related to long qt syndrome and postural orthostatic tachycardia syndrome. An important gene associated with Fainting is KCNS1 (potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1), and among its related pathways are Ca-dependent events and Visual Cycle in Retinal Rods. The compounds shk-dap22 and xe 991 dihydrochloride have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and skin.

NINDS:43 Syncope is a medical term used to describe a temporary loss of consciousness due to the sudden decline of blood flow to the brain. Syncope is commonly called fainting or ?passing out.? If an individual is about to faint, he or she will feel dizzy, lightheaded, or nauseous and their field of vision may ?white out? or ?black out.?

Wikipedia:63 Syncope (/ˈsɪŋkəpi/ SING-kə-pee), the medical term for fainting or passing out, is defined as a... more...

Aliases & Classifications for Fainting

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43NINDS, 33MedlinePlus
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Aliases & Descriptions:

fainting 43 33


Related Diseases for Fainting

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Fainting:



Diseases related to fainting

Clinical Features for Fainting

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Drugs & Therapeutics for Fainting

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Genetic Tests for Fainting

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Anatomical Context for Fainting

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32MalaCards
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MalaCards organs/tissues related to Fainting:

32
Brain, Heart, Skin

Animal Models for Fainting or affiliated genes

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Publications for Fainting

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Genetic Variations for Fainting

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Expression for genes affiliated with Fainting

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Fainting

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Pathways for genes affiliated with Fainting

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53Reactome, 51QIAGEN
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Compounds for genes affiliated with Fainting

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59Tocris Bioscience
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Compounds related to Fainting according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1shk-dap225910.6KCNG1, KCNS2, KCNF1, KCNS1, KCNV1
2xe 991 dihydrochloride5910.5KCNV1, KCNS1, KCNF1, KCNG1, KCNS2
3e-4031 dihydrochloride5910.5KCNG1, KCNS2, KCNF1, KCNS1, KCNV1
4jnj 3035910.5KCNG1, KCNS2, KCNF1, KCNS1, KCNV1
5suramin hexasodium salt5910.5GNAT2, GNAT1, GNAZ
6ica 1103815910.4KCNG1, KCNS2, KCNF1, KCNS1, KCNV1
7gallein5910.4GNAZ, GNAT1, GNAT2
8pertussis toxin5910.4GNAT2, GNAT1, GNAZ
9g-protein antagonist peptide5910.3GNAZ, GNAT1, GNAT2
108-bromo-cgmp, sodium salt5910.1GNAT2, GNAT1, GNAZ

GO Terms for genes affiliated with Fainting

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16Gene Ontology
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Cellular components related to Fainting according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extrinsic to internal side of plasma membraneGO:03123410.5GNAZ, GNAT1, GNAT2
2voltage-gated potassium channel complexGO:00807610.5KCNG1, KCNS2, KCNF1, KCNS1, KCNV1
3heterotrimeric G-protein complexGO:00583410.5GNAT2, GNAT1, GNAZ
4photoreceptor outer segmentGO:00175010.4GNAT1, GNAT2
5photoreceptor outer segment membraneGO:04262210.3GNAT2, GNAT1
6plasma membraneGO:00588610.2KCNV1, KCNS1, KCNF1, KCNS2, KCNG1, GNAT2
7photoreceptor inner segmentGO:00191710.1GNAT1, GNAT2

Biological processes related to Fainting according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1potassium ion transportGO:00681310.5KCNV1, KCNS1, KCNF1, KCNG1
2protein homooligomerizationGO:05126010.5KCNG1, KCNS2, KCNF1, KCNS1, KCNV1
3adenylate cyclase-modulating G-protein coupled receptor signaling pathwayGO:00718810.5GNAZ, GNAT1, GNAT2
4response to light intensityGO:00964210.5GNAT2, GNAT1
5sulfate transportGO:00827210.4SLC26A1, SLC26A10
6detection of chemical stimulus involved in sensory perception of bitter tasteGO:00158010.3GNAT2, GNAT1
7synaptic transmissionGO:00726810.3KCNG1, KCNS2, KCNF1, KCNS1, KCNV1
8detection of light stimulus involved in visual perceptionGO:05090810.1GNAT1, GNAT2

Molecular functions related to Fainting according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1G-protein beta/gamma-subunit complex bindingGO:03168310.5GNAZ, GNAT1, GNAT2
2delayed rectifier potassium channel activityGO:00525110.4KCNG1, KCNS2, KCNF1, KCNS1, KCNV1
3sulfate transmembrane transporter activityGO:01511610.4SLC26A10, SLC26A1
4potassium channel regulator activityGO:01545910.4KCNS1, KCNV1
5G-protein coupled receptor bindingGO:00166410.3GNAT1, GNAT2
6potassium channel activityGO:00526710.1KCNG1, KCNF1

Products for genes affiliated with Fainting

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Sources for Fainting

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet