Aliases & Classifications for Fainting

Aliases & Descriptions for Fainting:

Name: Fainting 51 41

Summaries for Fainting

MedlinePlus : 41 fainting is a temporary loss of consciousness. if you're about to faint, you'll feel dizzy, lightheaded, or nauseous. your field of vision may "white out" or "black out." your skin may be cold and clammy. you lose muscle control at the same time, and may fall down. fainting usually happens when your blood pressure drops suddenly, causing a decrease in blood flow to your brain. it is more common in older people. some causes of fainting include heat or dehydration emotional distress standing up too quickly certain medicines drop in blood sugar heart problems when someone faints, make sure that the airway is clear and check for breathing. the person should stay lying down for 10-15 minutes. most people recover completely. fainting is usually nothing to worry about, but it can sometimes be a sign of a serious problem. if you faint, it's important to see your health care provider and find out why it happened.

MalaCards based summary : Fainting is related to myocardial infarction and headache. An important gene associated with Fainting is KCNH2 (Potassium Voltage-Gated Channel Subfamily H Member 2), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. The drugs Amiodarone and Ranolazine have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and heart.

NINDS : 51 Syncope is a medical term used to describe a temporary loss of consciousness due to the sudden decline of blood flow to the brain. Syncope is commonly called fainting or “passing out.” If an individual is about to faint, he or she will feel dizzy, lightheaded, or nauseous and their field of vision may “white out” or “black out.”  The skin may be cold and clammy.  The person drops to the floor as he or she loses consciousness.  After fainting, an individual may be unconscious for a minute or two, but will revive and slowly return to normal.  Syncope can occur in otherwise healthy people and affects all age groups, but occurs more often in the elderly. 

Wikipedia : 71 Syncope, also known as fainting, is a short loss of consciousness and muscle strength characterized by a... more...

Related Diseases for Fainting

Diseases related to Fainting via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 94)
id Related Disease Score Top Affiliating Genes
1 myocardial infarction 30.3 CHKB F8 VWF
2 headache 28.7 CHKB F8 KCNH2 VWF
3 syncope 11.2
4 postural orthostatic tachycardia syndrome 10.9
5 chronic orthostatic intolerance 10.9
6 jervell and lange-nielsen syndrome 10.8
7 aortic valve disease 2 10.8
8 multiple system atrophy 10.7
9 osteogenesis imperfecta, type xiii 10.7
10 brugada syndrome 10.7
11 familial atrial fibrillation 10.7
12 atrial fibrillation 10.7
13 ectopic pregnancy 10.7
14 catecholaminergic polymorphic ventricular tachycardia 10.7
15 pulmonary hypertension, familial primary, 1, with or without hht 10.6
16 brugada syndrome 5 10.6
17 autoimmune autonomic ganglionopathy 10.6
18 cardiomyopathy, familial hypertrophic 10.6
19 andersen syndrome 10.6
20 patent foramen ovale 10.6
21 familial progressive cardiac conduction defect 10.6
22 brugada syndrome 2 10.6
23 pulmonary hypertension 10.6
24 brugada syndrome 1 10.6
25 vibratory urticaria 10.6
26 hereditary alpha tryptasemia syndrome 10.6
27 brugada syndrome 4 10.6
28 cardiomyopathy 10.6
29 long qt syndrome 1 10.6
30 arrhythmogenic right ventricular cardiomyopathy 10.6
31 atrial fibrillation and stroke 10.6
32 brugada syndrome 6 10.6
33 brugada syndrome 7 10.6
34 brugada syndrome 3 10.6
35 multiple system atrophy with orthostatic hypotension 10.6
36 brugada syndrome 9 10.6
37 ovarian cyst 10.6
38 hyperinsulinemic hypoglycemia, familial, 7 10.6
39 brugada syndrome 8 10.6
40 peters anomaly 10.6
41 syncope, familial vasovagal 10.6
42 amyloidosis 10.6
43 sick sinus syndrome 1 10.1 CHKB KCNH2
44 infiltrating ureter transitional cell carcinoma 10.0 CHKB F8
45 vcl-related familial hypertrophic cardiomyopathy 9.9 F8 VWF
46 vcp-related amyotrophic lateral sclerosis/frontotemporal dementia 9.9 F8 VWF
47 high anorectal malformation 9.9 F8 VWF
48 vcl-related dilated cardiomyopathy 9.9 F8 VWF
49 acromegaloid hypertrichosis syndrome 9.9 F8 VWF
50 alpha-2-macroglobulin deficiency 9.9 F8 VWF

Graphical network of the top 20 diseases related to Fainting:



Diseases related to Fainting

Symptoms & Phenotypes for Fainting

Drugs & Therapeutics for Fainting

Drugs for Fainting (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 235)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amiodarone Approved, Investigational Phase 4,Phase 3 1951-25-3 2157
2
Ranolazine Approved, Investigational Phase 4,Phase 2 142387-99-3, 95635-55-5 56959
3
Testosterone Approved, Investigational Phase 4 58-22-0 6013
4
Losartan Approved Phase 4 114798-26-4 3961
5
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3 58-93-5 3639
6
Amlodipine Approved Phase 4 88150-42-9 2162
7
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
8
Propranolol Approved, Investigational Phase 4,Phase 2 525-66-6 4946
9
Midodrine Approved Phase 4 133163-28-7, 42794-76-3 4195
10
Fludrocortisone Approved Phase 4 127-31-1 31378
11
Treprostinil Approved, Investigational Phase 4 81846-19-7 54786 6918140
12
Epoprostenol Approved Phase 4 61849-14-7, 35121-78-9 5280427 5282411
13
Methyltestosterone Approved Phase 4 58-18-4 6010
14
Donepezil Approved Phase 4 120014-06-4 3152
15 Sodium Channel Blockers Phase 4,Phase 3,Phase 2
16 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
17 Cytochrome P-450 CYP1A2 Inhibitors Phase 4,Phase 3
18 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 3
19 Cytochrome P-450 CYP2D6 Inhibitors Phase 4,Phase 3
20 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 3
21 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
22 Diuretics, Potassium Sparing Phase 4,Phase 3,Phase 2
23 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
24 Vasodilator Agents Phase 4,Phase 3,Phase 2
25 Anti-Arrhythmia Agents Phase 4,Phase 3,Phase 2
26 Potassium Channel Blockers Phase 4,Phase 3
27 Anti-Inflammatory Agents Phase 4,Phase 1,Phase 2
28
Angiotensin II Phase 4,Phase 3 68521-88-0, 11128-99-7 65143 172198
29 Tezosentan Phase 4
30 Testosterone undecanoate Phase 4
31 calcium channel blockers Phase 4
32 diuretics Phase 4,Phase 3,Phase 1,Phase 2
33 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
34 Natriuretic Agents Phase 4,Phase 3,Phase 1,Phase 2
35 Adrenergic Agonists Phase 4,Phase 1,Phase 2,Early Phase 1
36 Adrenergic Antagonists Phase 4,Phase 3,Phase 2
37 Adrenergic alpha-Agonists Phase 4,Phase 1,Phase 2,Early Phase 1
38 Sodium Chloride Symporter Inhibitors Phase 4,Phase 3
39 Adrenergic beta-1 Receptor Antagonists Phase 4,Phase 3
40 Adrenergic beta-Antagonists Phase 4,Phase 3,Phase 2,Phase 1
41 Sympatholytics Phase 4,Phase 3
42 Testosterone 17 beta-cypionate Phase 4
43
Testosterone enanthate Phase 4 315-37-7 9416
44 Anabolic Agents Phase 4
45 Hormone Antagonists Phase 4
46 Androgens Phase 4
47 Hormones Phase 4,Phase 1,Phase 2
48 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
49 Vasoconstrictor Agents Phase 4,Phase 1,Phase 2,Early Phase 1
50 Angiotensin II Type 1 Receptor Blockers Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 282)
id Name Status NCT ID Phase
1 Closed Loop Stimulation for Neuromediated Syncope (SPAIN Study) Unknown status NCT01621464 Phase 4
2 Safety of Amiodarone and Ranolazine Together in Patients With Angina Unknown status NCT01558830 Phase 4
3 Clinical Trial for the Prevention of Vasovagal Syncope Completed NCT00118482 Phase 4
4 ISSUE3: International Study on Syncope of Uncertain Etiology 3 Completed NCT00359203 Phase 4
5 Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance Completed NCT00060866 Phase 4
6 ELIAS: Early Loop-Recorder in Suspected Arrhythmogenic Syncope Completed NCT00170261 Phase 4
7 Comparision of Blood Pressure Variability Between Amlodipine and Losartan Completed NCT01964079 Phase 4
8 Tilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension Completed NCT01518946 Phase 4
9 Multicenter Automatic Defibrillator Implantation Trial - Reduce Inappropriate Therapy Completed NCT00947310 Phase 4
10 Programming Implantable Cardioverter Defibrillators in Patients With Primary Prevention Indication Completed NCT00743522 Phase 4
11 Physiologic Evaluation of Anomalous Right Coronary Artery Stenosis Completed NCT01133054 Phase 4
12 A Comparison of Polyglactin 910 and Chromic Gut Suture in the Closure of Punch Biopsy Sites Completed NCT01722994 Phase 4
13 Effects of Testosterone on Myocardial Repolarization Completed NCT03126656 Phase 4
14 Safety, Efficacy and Treatment Satisfaction in Patients With PAH Rapidly Switched From Epoprostenol to Remodulin Completed NCT00373360 Phase 4
15 Assessment of Midodrine in the Prevention of Vasovagal Syncope: The Prevention of Syncope Trial IV Recruiting NCT01456481 Phase 4
16 Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects Recruiting NCT02123056 Phase 4
17 Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human Adults Recruiting NCT03109314 Phase 4
18 Evaluation of PCLs Using Three EUS-FNA Needles Recruiting NCT01711294 Phase 4
19 Syncope: Pacing or Recording in the Later Years Active, not recruiting NCT01423994 Phase 4
20 International Study on Syncope of Uncertain Etiology Terminated NCT00120094 Phase 4
21 A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension Terminated NCT00046163 Phase 4
22 Rapid Switch From Flolan to Remodulin in the Outpatient Clinic Terminated NCT00643604 Phase 4
23 Safety, Efficacy, and Treatment Satisfaction Switching From Flolan to Remodulin Using the Crono Five Ambulatory Pump in Patients With PAH Terminated NCT00439946 Phase 4
24 Adenosine Testing to DEtermine the Need for Pacing Therapy Unknown status NCT01481168 Phase 3
25 Lactobacillus Reuteri in Treatment of Functional Abdominal Pain and Chronic Constipation in Children Unknown status NCT01587846 Phase 3
26 Stop Vasodepressor Drugs in Reflex Syncope Completed NCT02137278 Phase 3
27 A Two Part Study (306A/306B) to Assess Droxidopa in Treatment of NOH in Patients With Parkinson's Disease Completed NCT01176240 Phase 3
28 Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00633880 Phase 3
29 Ablation of Clinical Ventricular Tachycardia Versus Addition of Substrate Ablation on the Long Term Success Rate of VT Ablation Completed NCT01045668 Phase 3
30 Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy for Patients With Moderate Hypertension Completed NCT00095550 Phase 3
31 Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy as First Line Treatment for Severe Hypertension Completed NCT00095394 Phase 3
32 Induction With Foley OR Misoprostol (INFORM) Study Completed NCT01801410 Phase 3
33 Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor Completed NCT00308711 Phase 3
34 Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD Completed NCT00532493 Phase 3
35 Chagas Cardiomyopathy Bisoprolol Intervention Study: Charity Completed NCT00323973 Phase 3
36 A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa Completed NCT00782340 Phase 3
37 Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) Completed NCT00738062 Phase 3
38 Efficacy of Transcatheter Ablation Using Anatomic Approach of Ganglionated Plexi Located in the Right Atrium to Prevent Neuromediated Cardioinhibitory Syncope Recruiting NCT01814228 Phase 3
39 Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections. Recruiting NCT02809131 Phase 3
40 Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction Recruiting NCT00673842 Phase 3
41 Effects of PTH Replacement on Bone in Hypoparathyroidism Active, not recruiting NCT00395538 Phase 3
42 Ballooned Intercostal Drain Trial Not yet recruiting NCT03000504 Phase 3
43 Effect of Chronic Oral Hydration in Patients With Recurrent Unexplained Syncope Terminated NCT00143754 Phase 3
44 A Clinical Study of Patients With Symptomatic NOH to Assess Sustained Effects of Droxidopa Therapy Terminated NCT01927055 Phase 3
45 Hydroquinidine Versus Placebo in Patients With Brugada Syndrome Terminated NCT00927732 Phase 3
46 Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy Withdrawn NCT01560091 Phase 3
47 Evaluate the Noninferiority of Medicines Treating Uninfected Pressure Ulcers. Withdrawn NCT02004626 Phase 3
48 Trial Comparing Ablation With Medical Therapy in Patients With Ventricular Tachycardia Withdrawn NCT01798277 Phase 3
49 ASIS for Enbrel in Plaque Psoriasis Unknown status NCT02112097 Phase 1, Phase 2
50 Non-Pharmacologic Therapy for Neurocardiogenic Syncope Completed NCT00096902 Phase 2

Search NIH Clinical Center for Fainting

Genetic Tests for Fainting

Anatomical Context for Fainting

MalaCards organs/tissues related to Fainting:

39
Skin, Brain, Heart, Testes, Whole Blood, Pituitary, Skeletal Muscle

Publications for Fainting

Articles related to Fainting:

(show top 50) (show all 197)
id Title Authors Year
1
Syncope (Fainting). ( 27142609 )
2016
2
Syncope: Not for the faint hearted. ( 27189260 )
2016
3
An Experimental Model of Vasovagal Syncope Induces Cerebral Hypoperfusion and Fainting-Like Behavior in Awake Rats. ( 27658057 )
2016
4
Fainting Starting Parenteral Nutrition. ( 25853719 )
2015
5
Fifteen-minute consultation on limiting investigations in the fainting child. ( 26201347 )
2015
6
Prognosis of glioblastoma with faint MGMT methylation-specific PCR product. ( 25575938 )
2015
7
Fainting After Chest Pain. ( 27122877 )
2015
8
Fainting as an unusual presentation of a large inferior vena cava leiomyosarcoma. ( 24837084 )
2014
9
Role of sympathetic nerve activity in the process of fainting. ( 25309444 )
2014
10
Giving blood donors something to drink before donation can prevent fainting symptoms: is there a physiological or psychological reason? ( 25130724 )
2014
11
A mobile system for real-time context-aware monitoring of patients' health and fainting. ( 25946886 )
2014
12
Purinergic profile of fainting divers is different from patients with vasovagal syncope. ( 24798778 )
2014
13
Alteration in cardiovascular and postural control relationship in non-fainting elderly individuals. ( 25570750 )
2014
14
Fainting (vasovagal syncope): case reports. ( 25198333 )
2014
15
Skin infiltration of nodal peripheral t-cell lymphoma-not otherwise specified identified by skin biopsy of faint eruptions. ( 23723524 )
2013
16
Small left atrial volume is an independent predictor for fainting during head-up tilt test: the impact of intracardiac volume reserve in vasovagal syncope. ( 22000265 )
2013
17
Malignant cardioinhibitory vasovagal syncope - an uncommon cardiovascular complication of Roux-en-Y gastric bypass surgery: the fainting syndrome! ( 23063207 )
2013
18
Long-Term Stability of Uveitis with Faint Anterior Chamber Flare Treated with Once-Daily Topical Ophthalmic Betamethasone. ( 24114448 )
2013
19
57-year-old man with flushing and fainting. ( 23639502 )
2013
20
External pneumatic compression device prevents fainting in standing weight-bearing MRI: a cohort study. ( 23857423 )
2013
21
The relation between disgust-sensitivity, blood-injection-injury fears and vasovagal symptoms in blood donors: disgust sensitivity cannot explain fainting or blood donation-related symptoms. ( 21906532 )
2012
22
Case 2: 'I feel faint': An adolescent with recurrent dizziness and syncope. ( 23730166 )
2012
23
Does disgust increase parasympathetic activation in individuals with a history of fainting? A psychophysiological analysis of disgust stimuli with and without blood-injection-injury association. ( 23023164 )
2012
24
Fainting attacks in children. ( 21695380 )
2012
25
What's at the heart of fainting? Most fainting is not related to abnormal heart rhythms. ( 22872881 )
2012
26
Sensitivity of MDM2 amplification and unexpected multiple faint alphoid 12 (alpha 12 satellite sequences) signals in atypical lipomatous tumor. ( 22699518 )
2012
27
A pacemaker to prevent fainting. If your heart rate slows, a device can stop you from dropping. ( 23101130 )
2012
28
A 40-year-old man with recurrent fainting, hypotension, lower limb edema and oliguria with body weight gain and secondary erythrocytosis. ( 21948352 )
2012
29
Fainting, swooning, and syncope. ( 22132356 )
2011
30
Factors associated with fainting: before, during and after whole blood donation. ( 21535440 )
2011
31
Episode of fainting and tetany after an evaluation technique of the upper cervical region: a case report. ( 20724209 )
2011
32
Physiologic strategies to prevent fainting responses during or after whole blood donation. ( 21645008 )
2011
33
To avoid fainting: cross the legs and not the fingers. ( 20106794 )
2010
34
Correlations between urinary excretion of catecholamines and electrocardiographic parameters of vagal hyperreactivity in infants with fainting spells. Implication of sympathetic hypotonia? ( 21074121 )
2010
35
Fainting with HIV. ( 20800149 )
2010
36
Clinical reasoning: a teenage girl with excessive daytime sleepiness, "fainting spells," and dream mentations. ( 20498429 )
2010
37
A 37-year-old man with recurrent fainting: a short communication. ( 20348158 )
2010
38
Pituitary adenomas that show a faint GH-immunoreactivity but lack fibrous body: Pit-1 adenoma with endocrinologically low activity. ( 20111911 )
2010
39
A 46-year-old woman with chin pain and a fainting spell. ( 20391493 )
2010
40
Diagnostic tests for fainting found expensive, ineffective. The cheapest test for syncope--a postural blood pressure recording--may yield the most answers. ( 20120509 )
2009
41
Physiological correlates of applied tension may contribute to reduced fainting during medical procedures. ( 19730965 )
2009
42
Low creatine kinase is associated with a high population incidence of fainting. ( 19468786 )
2009
43
Increased phase synchronization and decreased cerebral autoregulation during fainting in the young. ( 19820196 )
2009
44
Fainting, emancipation and the 'weak and sensitive' sex. ( 19567743 )
2009
45
Persistent fainting after implantation of a "curative" pacemaker. ( 19118314 )
2009
46
Behavioral avoidance and self-reported fainting symptoms in blood/injury fearful individuals: an experimental test of disgust domain specificity. ( 17920808 )
2008
47
Fainting and hemolysis during blood sampling in youngsters: prevalence study. ( 17331515 )
2008
48
By the way, doctor. Do I need to go to the ER after fainting? ( 18697270 )
2008
49
Ask the doctor. I want to donate blood, but I faint or come close to it nearly every time I have blood drawn at the doctor's office. Can I do anything to keep myself from fainting? ( 18822512 )
2008
50
The Arg389Gly beta1-adrenergic receptor gene polymorphism and susceptibility to faint during head-up tilt test. ( 17463065 )
2007

Variations for Fainting

Expression for Fainting

Search GEO for disease gene expression data for Fainting.

Pathways for Fainting

GO Terms for Fainting

Cellular components related to Fainting according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 platelet alpha granule lumen GO:0031093 8.62 F8 VWF

Biological processes related to Fainting according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.32 F8 VWF
2 platelet degranulation GO:0002576 9.26 F8 VWF
3 platelet activation GO:0030168 9.16 F8 VWF
4 hemostasis GO:0007599 8.96 F8 VWF
5 blood coagulation, intrinsic pathway GO:0007597 8.62 F8 VWF

Sources for Fainting

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11 DGIdb
16 ExPASy
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28 GO
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30 HGMD
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33 ICD10
34 ICD10 via Orphanet
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36 IUPHAR
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43 MESH via Orphanet
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48 NDF-RT
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52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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