MCID: FLL028
MIFTS: 22

Fallopian Tube Carcinosarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Fallopian Tube Carcinosarcoma

MalaCards integrated aliases for Fallopian Tube Carcinosarcoma:

Name: Fallopian Tube Carcinosarcoma 12 14 69
Fallopian Tube Malignant Mixed Mesodermal Tumor 12
Fallopian Tube Malignant Mixed Mullerian Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1970
NCIt 47 C40124
UMLS 69 C1517117

Summaries for Fallopian Tube Carcinosarcoma

Disease Ontology : 12 A fallopian tube cancer that is characterized as a mixture of carcinoma and sarcoma and has material basis in epithelial tissue and has material basis in connective tissue.

MalaCards based summary : Fallopian Tube Carcinosarcoma, also known as fallopian tube malignant mixed mesodermal tumor, is related to uremia and childhood pleomorphic rhabdomyosarcoma. An important gene associated with Fallopian Tube Carcinosarcoma is WT1 (Wilms Tumor 1), and among its related pathways/superpathways is Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Carboplatin and Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include liver, endothelial and brain.

Related Diseases for Fallopian Tube Carcinosarcoma

Diseases related to Fallopian Tube Carcinosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 33)
id Related Disease Score Top Affiliating Genes
1 uremia 10.1 CALB2 WT1
2 childhood pleomorphic rhabdomyosarcoma 10.1 CALB2 WT1
3 ovary neuroendocrine neoplasm 10.1 CALB2 WT1
4 malignant peritoneal solitary fibrous tumor 10.1 CALB2 WT1
5 cutaneous liposarcoma 10.1 CALB2 WT1
6 pancreatic ductal carcinoma 10.0 CALB2 WT1
7 mesenteric vascular occlusion 10.0 CALB2 WT1
8 arteriolosclerosis 10.0 CALB2 WT1
9 plantar fasciitis 10.0 CALB2 WT1
10 nasal cavity squamous cell carcinoma 10.0 CALB2 WT1
11 chondroblastoma 10.0 CALB2 WT1
12 avian influenza 10.0 CALB2 WT1
13 clear cell adenofibroma 9.9 CALB2 NCAM1
14 prion disease 9.9 CALB2 NCAM1
15 iris spindle cell melanoma 9.9 CALB2 NCAM1
16 perivascular epithelioid cell tumor 9.9 CALB2 WT1
17 trachea sarcoma 9.8 CALB2 NCAM1
18 cervical neuroblastoma 9.8 CALB2 WT1
19 urethral villous adenoma 9.8 CALB2 NCAM1
20 mediastinum synovial sarcoma 9.8 CALB2 NCAM1
21 mucinous adenofibroma 9.8 NCAM1 WT1
22 stromal predominant kidney wilms' tumor 9.8 NCAM1 WT1
23 mesothelioma, somatic 9.8 CALB2 WT1
24 epilepsy with generalized tonic-clonic seizures 9.7 CALB2 NCAM1
25 large cell carcinoma with rhabdoid phenotype 9.7 CALB2 WT1
26 nodular tenosynovitis 9.6 NCAM1 WT1
27 lung clear cell-sugar-tumor 9.6 NCAM1 WT1
28 myasthenic syndrome, congenital, 21, presynaptic 9.4 CALB2 NCAM1
29 cranioectodermal dysplasia 1 9.4 NCAM1 WT1
30 thymus lipoma 9.3 CALB2 NCAM1 WT1
31 hypogonadism 9.3 CALB2 NCAM1 WT1
32 hyperbiliverdinemia 9.3 CALB2 NCAM1 WT1
33 kala-azar 1 9.1 NCAM1 WT1

Graphical network of the top 20 diseases related to Fallopian Tube Carcinosarcoma:



Diseases related to Fallopian Tube Carcinosarcoma

Symptoms & Phenotypes for Fallopian Tube Carcinosarcoma

Drugs & Therapeutics for Fallopian Tube Carcinosarcoma

Drugs for Fallopian Tube Carcinosarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
2
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
3
Bevacizumab Approved, Investigational Phase 3,Phase 2,Phase 1 216974-75-3
4
Ifosfamide Approved Phase 3 3778-73-2 3690
5
Mechlorethamine Approved Phase 3 51-75-2 4033
6 Albumin-Bound Paclitaxel Phase 3,Phase 2,Phase 1
7 Antimitotic Agents Phase 3,Phase 2,Phase 1
8 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
9 Angiogenesis Inhibitors Phase 3,Phase 2,Phase 1
10 Angiogenesis Modulating Agents Phase 3,Phase 2,Phase 1
11 Alkylating Agents Phase 3
12 Isophosphamide mustard Phase 3
13
Gemcitabine Approved Phase 2 95058-81-4 60750
14
Cisplatin Approved Phase 2,Phase 1 15663-27-1 84093 441203 2767
15
Doxorubicin Approved, Investigational Phase 2,Phase 1 23214-92-8 31703
16
Everolimus Approved Phase 2 159351-69-6 6442177
17
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
18
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353
19
Doxil Approved June 1999 Phase 2,Phase 1 31703
20 Anti-Infective Agents Phase 2
21 Antimetabolites Phase 2
22 Antimetabolites, Antineoplastic Phase 2
23 Antiviral Agents Phase 2
24 Immunosuppressive Agents Phase 2
25 Anti-Bacterial Agents Phase 2,Phase 1
26 Antibiotics, Antitubercular Phase 2,Phase 1
27 Topoisomerase Inhibitors Phase 2,Phase 1
28 Endothelial Growth Factors Phase 2,Phase 1
29 Mitogens Phase 2,Phase 1
30
Erlotinib Hydrochloride Phase 2 183319-69-9 176871
31 Protein Kinase Inhibitors Phase 2
32 Antibodies Phase 2,Phase 1
33 Antibodies, Monoclonal Phase 2,Phase 1
34 Antifungal Agents Phase 2
35 Immunoglobulins Phase 2,Phase 1
36 Liver Extracts Phase 2
37
Lenograstim Approved Phase 1 135968-09-1
38
Docetaxel Approved May 1996, Investigational Phase 1 114977-28-5 148124 9877265
39
Veliparib Investigational Phase 1 912444-00-9 11960529
40 Immunotoxins Phase 1
41 Poly(ADP-ribose) Polymerase Inhibitors Phase 1

Interventional clinical trials:

(show all 16)

id Name Status NCT ID Phase Drugs
1 Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Newly Diagnosed Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer Completed NCT00483782 Phase 3 carboplatin;paclitaxel
2 Paclitaxel and Carboplatin or Ifosfamide in Treating Patients With Newly Diagnosed, Persistent or Recurrent Uterine, Ovarian, Fallopian Tube, or Peritoneal Cavity Cancer Active, not recruiting NCT00954174 Phase 3 Carboplatin;Ifosfamide;Paclitaxel
3 Two Different Schedules of Carboplatin, Paclitaxel, Gemcitabine, and Surgery in Treating Patients With Newly Diagnosed Stage IIIC or Stage IV Primary Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer Unknown status NCT00838656 Phase 2 carboplatin;gemcitabine hydrochloride;paclitaxel
4 Study of Bevacizumab Followed by Bevacizumab Consolidation for Ovarian Cancer Completed NCT00511992 Phase 2 Avastin;Paclitaxel;Cisplatin
5 Combination Chemotherapy in Treating Patients With Endometrial Cancer, Fallopian Tube Cancer, or Sarcoma of the Female Reproductive Tract Completed NCT00003334 Phase 2 paclitaxel;pegylated liposomal doxorubicin hydrochloride
6 Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma Completed NCT00390234 Phase 2 ziv-aflibercept
7 Avastin +/- Erlotinib Consolidation Chemotherapy After Carboplatin, Paclitaxel, and Avastin (CTA) Induction Therapy for Advanced Ovarian, Fallopian Tube, Primary Peritoneal Cancer & Papillary Serous or Clear Cell Mullerian Tumors Completed NCT00520013 Phase 2 bevacizumab;erlotinib;paclitaxel;carboplatin
8 Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell Cancer Completed NCT01010126 Phase 2 Temsirolimus
9 Liposomal Doxorubicin and Carboplatin in Treating Patients With Gynecologic Cancer Completed NCT00032162 Phase 1, Phase 2 carboplatin;pegylated liposomal doxorubicin hydrochloride
10 Gemcitabine Hydrochloride With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Recruiting NCT02101775 Phase 2 Gemcitabine Hydrochloride;WEE1 Inhibitor AZD1775
11 Carboplatin, Paclitaxel, and Pegfilgrastim in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Fallopian Tube, Primary Peritoneal, or Carcinosarcoma Cancer Completed NCT00352300 Phase 1 Carboplatin;Paclitaxel
12 Carboplatin and Paclitaxel With or Without Bevacizumab Compared to Docetaxel, Carboplatin, and Paclitaxel in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Carcinoma (Cancer) Completed NCT00085358 Phase 1 carboplatin;paclitaxel;docetaxel
13 Immunotoxin Therapy in Treating Patients With Advanced Solid Tumors Completed NCT00066651 Phase 1
14 Carboplatin, Paclitaxel, Bevacizumab, and Veliparib in Treating Patients With Newly Diagnosed Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer Active, not recruiting NCT00989651 Phase 1 Carboplatin;Cisplatin;Paclitaxel;Veliparib
15 Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Bevacizumab in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery or Gynecological Cancers Suspended NCT02020707 Phase 1 Paclitaxel Albumin-Stabilized Nanoparticle Formulation
16 Changes in Brain Function in Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Are Receiving Chemotherapy Active, not recruiting NCT01080521

Search NIH Clinical Center for Fallopian Tube Carcinosarcoma

Genetic Tests for Fallopian Tube Carcinosarcoma

Anatomical Context for Fallopian Tube Carcinosarcoma

MalaCards organs/tissues related to Fallopian Tube Carcinosarcoma:

39
Liver, Endothelial, Brain

Publications for Fallopian Tube Carcinosarcoma

Variations for Fallopian Tube Carcinosarcoma

Expression for Fallopian Tube Carcinosarcoma

Search GEO for disease gene expression data for Fallopian Tube Carcinosarcoma.

Pathways for Fallopian Tube Carcinosarcoma

Pathways related to Fallopian Tube Carcinosarcoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.75 NCAM1 WT1

GO Terms for Fallopian Tube Carcinosarcoma

Sources for Fallopian Tube Carcinosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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