MCID: FML155

Familial Acute Myeloid Leukemia with Mutated Cebpa malady

Genetic diseases (common) category

Summaries for Familial Acute Myeloid Leukemia with Mutated Cebpa

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22Genetics Home Reference, 20GeneReviews, 34MalaCards
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Genetics Home Reference:22 Familial acute myeloid leukemia with mutated CEBPA is one form of a cancer of the blood-forming tissue (bone marrow) called acute myeloid leukemia. In normal bone marrow, early blood cells called hematopoietic stem cells develop into several types of blood cells: white blood cells (leukocytes) that protect the body from infection, red blood cells (erythrocytes) that carry oxygen, and platelets (thrombocytes) that are involved in blood clotting. In acute myeloid leukemia, the bone marrow makes large numbers of abnormal, immature white blood cells called myeloid blasts. Instead of developing into normal white blood cells, the myeloid blasts develop into cancerous leukemia cells. The large number of abnormal cells in the bone marrow interferes with the production of functional white blood cells, red blood cells, and platelets.

MalaCards: Familial Acute Myeloid Leukemia with Mutated Cebpa, also known as cebpa-dependent familial acute myeloid leukemia, is related to pelger-huet anomaly. An important gene associated with Familial Acute Myeloid Leukemia with Mutated Cebpa is CEBPA (CCAAT/enhancer binding protein (C/EBP), alpha). Affiliated tissues include myeloid.

GeneReviews summary for cebpa-aml

Aliases & Classifications for Familial Acute Myeloid Leukemia with Mutated Cebpa

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20GeneReviews, 21GeneTests, 22Genetics Home Reference
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Classifications:

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Global: Genetic diseases (common)


Aliases & Descriptions:

familial acute myeloid leukemia with mutated cebpa 20 21 22
cebpa-dependent familial acute myeloid leukemia 20 22
familial acute myeloid leukaemia 22


Related Diseases for Familial Acute Myeloid Leukemia with Mutated Cebpa

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18GeneCards, 19GeneDecks
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Diseases related to Familial Acute Myeloid Leukemia with Mutated Cebpa via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1pelger-huet anomaly10.3

Symptoms for Familial Acute Myeloid Leukemia with Mutated Cebpa

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Drugs & Therapeutics for Familial Acute Myeloid Leukemia with Mutated Cebpa

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Genetic Tests for Familial Acute Myeloid Leukemia with Mutated Cebpa

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Genetic tests related to Familial Acute Myeloid Leukemia with Mutated Cebpa:

id Genetic test Affiliating Genes
1 Familial Acute Myeloid Leukemia (aml) with Mutated Cebpa21 CEBPA

Anatomical Context for Familial Acute Myeloid Leukemia with Mutated Cebpa

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MalaCards organs/tissues related to Familial Acute Myeloid Leukemia with Mutated Cebpa:

34
Myeloid

Animal Models for Familial Acute Myeloid Leukemia with Mutated Cebpa or affiliated genes

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Publications for Familial Acute Myeloid Leukemia with Mutated Cebpa

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Variations for Familial Acute Myeloid Leukemia with Mutated Cebpa

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Expression for genes affiliated with Familial Acute Myeloid Leukemia with Mutated Cebpa

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Familial Acute Myeloid Leukemia with Mutated Cebpa

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Pathways for genes affiliated with Familial Acute Myeloid Leukemia with Mutated Cebpa

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Compounds for genes affiliated with Familial Acute Myeloid Leukemia with Mutated Cebpa

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GO Terms for genes affiliated with Familial Acute Myeloid Leukemia with Mutated Cebpa

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Products for genes affiliated with Familial Acute Myeloid Leukemia with Mutated Cebpa

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  • Antibodies
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Sources for Familial Acute Myeloid Leukemia with Mutated Cebpa

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet