MCID: FML108
MIFTS: 57

Familial Breast Cancer malady

Categories: Genetic diseases, Rare diseases, Reproductive diseases, Cancer diseases

Aliases & Classifications for Familial Breast Cancer

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Sources:
31ICD10 via Orphanet, 48NIH Rare Diseases, 54Orphanet, 68UMLS
See all MalaCards sources

Summaries for Familial Breast Cancer

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NIH Rare Diseases:48 Familial breast cancer is a cluster of breast cancer within a family. Most cases of breast cancer occur sporadically in people with little to no family history of the condition. Approximately 5-10% of breast cancer is considered hereditary and is thought to be caused by an inherited predisposition to breast cancer that is passed down through a family in an autosomal dominant manner. In some of these families, the underlying genetic cause is not known; however, many of these cases are caused by changes (mutations) in the BRCA1, BRCA2, PTEN, TP53, CDH1, or STK11 genes (which are each associated with a unique hereditary cancer syndrome). An additional 15-20% of women diagnosed with breast cancer have a significant family history of breast cancer (two or more first-degree or second-degree relatives with breast cancer) but have no identifiable mutation in a gene known to cause a hereditary predisposition to breast cancer. These clusters of breast cancer are likely due to a combination of gene(s) and other shared factors such as environment and lifestyle.High-risk cancer screening and other preventative measures such as chemoprevention and/or prophylactic surgeries are typically recommended in women who have an increased risk for breast cancer based on their personal and/or family histories. Last updated: 3/23/2015

MalaCards based summary: Familial Breast Cancer, also known as hereditary breast carcinoma, is related to prostate cancer and breast cancer. An important gene associated with Familial Breast Cancer is BRCA1 (BRCA1, DNA Repair Associated), and among its related pathways are PLK3 signaling events and DNA Damage Induced 14-3-3Sigma Signaling. Affiliated tissues include breast, lung and testes, and related mouse phenotypes are Decreased viability with cisplatin and Synthetic lethal with cisplatin.

Related Diseases for Familial Breast Cancer

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Diseases in the Breast Cancer family:

Breast Benign Neoplasm Inflammatory Breast Carcinoma
Sporadic Breast Cancer Breast Carcinoma in Situ
familial breast cancer Bard1-Related Susceptibility to Breast Cancer
Brip1-Related Breast Cancer Chek2-Related Susceptibility to Breast Cancer
Rad51-Related Susceptibility to Breast Cancer

Diseases related to Familial Breast Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 109)
idRelated DiseaseScoreTop Affiliating Genes
1prostate cancer29.9ATM, BRCA1, BRCA2, CCND1, CHEK2, ERBB2
2breast cancer28.7ATM, BARD1, BRCA1, BRCA2, BRIP1, CCND1
3congenital pulmonary veins atresia or stenosis10.9BRCA1, BRCA2
4liddle syndrome, scnn1g-related10.9CHEK2, TP53
5eyelid disease10.9ERBB2, ESR1
6gelatinous ascites10.9ERBB2, ESR1
7bronchopulmonary dysplasia10.9BRCA1, BRCA2
8cutaneous lupus erythematosus10.9BRCA1, BRCA2, ERBB2
9autoimmune disease of blood10.9BRCA1, BRCA2
10fallopian tube germ cell cancer10.9BRCA1, BRCA2, ESR1
11skeletal tuberculosis10.9CCND1, ERBB2
12ovarian brenner tumor10.9BRCA1, BRCA2, TP53
13selective ige deficiency disease10.9BRCA1, BRCA2
14trigeminal nerve disease10.9BRCA1, ERBB2, ESR1
15papillary adenofibroma10.9BRCA1, BRCA2, TP53
16bile duct disease10.8ATM, BRCA1, TP53
17immune system cancer10.8BRCA1, ERBB2, ESR1
18cystinosis, nephropathic10.8ERBB2, TP53
19cell type benign neoplasm10.8ERBB2, ESR1, TP53
20cartilage cancer10.8ERBB2, ESR1, TP53
21vibratory urticaria10.8ERBB2, ESR1, TP53
22breast cancer, childhood10.8BRCA1, BRCA2, CHEK2, PALB2
23breast adenoma10.8ERBB2, ESR1, TP53
24acral lentiginous melanoma10.8ATM, CCND1, TP53
25nerve fibre bundle defect10.8ERBB2, ESR1, TP53
26lethal congenital contracture syndrome 710.8BRCA1, BRCA2
27vulval paget's disease10.8ERBB2, ESR1, TP53
28fallopian tube mucinous adenocarcinoma10.8ERBB2, ESR1, TP53
29charcot-marie-tooth disease, type 4b110.8ATM, CHEK2, RAD50
30stroma-dominant and stroma-poor composite ganglioneuroblastoma10.8ERBB2, RAD51, TP53
31cervical serous adenocarcinoma10.8BRCA1, BRCA2, ERBB2, TP53
32rectum mucinous adenocarcinoma10.8BRCA1, BRCA2, ERBB2, TP53
33ovarian cancer, somatic10.8BRCA1, BRCA2, ERBB2, PALB2
34cholesteatoma of external ear10.8BRCA1, ERBB2, ESR1, TP53
35distal monosomy 9p10.8BRCA1, BRCA2, ERBB2, TP53
36kidney benign neoplasm10.8CCND1, ERBB2, TP53
37nodular degeneration of cornea10.8ERBB2, ESR1, TP53
38blepharochalasis10.8ERBB2, ESR1, TP53
39dysgraphia10.8CCND1, ERBB2, TP53
40arthrogryposis, renal dysfunction, and cholestasis 110.8ATM, BRCA1, BRCA2, RAD51
41novak syndrome10.8CCND1, ERBB2, ESR1, TP53
42progesterone-receptor positive breast cancer10.8CCND1, ERBB2, ESR1, TP53
43lobular neoplasia10.8CCND1, ERBB2, ESR1, TP53
44brown-vialetto-van laere syndrome10.7CCND1, ERBB2, ESR1, TP53
45myopathy10.7CCND1, ESR1, TP53
46leiomyosarcoma10.7BRCA1, BRCA2, ERBB2, ESR1, TP53
47extragonadal nonseminomatous germ cell tumor10.7ERBB2, ESR1
48dental caries10.7BRCA1, BRCA2, ERBB2, ESR1, TP53
49milker's nodule10.7BRCA1, BRCA2, ERBB2, ESR1, TP53
50plasmacytoma10.7CCND1, ERBB2, TP53

Graphical network of the top 20 diseases related to Familial Breast Cancer:



Diseases related to familial breast cancer

Symptoms & Phenotypes for Familial Breast Cancer

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GenomeRNAi Phenotypes related to Familial Breast Cancer according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00101-A-410.7BARD1, BRCA1, BRCA2, BRIP1, RAD51
2GR00101-A-110.5BARD1, BRCA1, BRCA2, BRIP1, RAD51, XRCC3
3GR00151-A-29.5BARD1, BRCA1, BRCA2, PALB2, RAD51, ATM
4GR00235-A9.5BRCA1, BRCA2, CCND1, CHEK2, ERBB2, ESR1
5GR00250-A-38.9ATM, BARD1, BRCA1, BRCA2, BRIP1, CHEK2
6GR00250-A-17.3ATM, BARD1, BRCA1, BRCA2, BRIP1, CCND1

MGI Mouse Phenotypes related to Familial Breast Cancer according to GeneCards Suite gene sharing:

41 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.9BRCA1, CCND1, ERBB2, ESR1, RAD50, TP53
2MP:00053719.8BRCA1, BRCA2, ERBB2, ESR1, PALB2, RAD50
3MP:00028739.7BARD1, BRCA1, BRCA2, CCND1, ERBB2, ESR1
4MP:00053899.6ATM, BRCA1, BRCA2, BRIP1, CCND1, ERBB2
5MP:00053819.6BRCA1, BRCA2, CCND1, ERBB2, ESR1, RAD50
6MP:00053809.5ATM, BARD1, BRCA1, BRCA2, ERBB2, ESR1
7MP:00053799.5ATM, BRCA1, BRCA2, BRIP1, CCND1, ERBB2
8MP:00053879.3ATM, BRCA1, BRCA2, CCND1, CHEK2, ESR1
9MP:00053979.3ATM, BRCA1, BRCA2, CCND1, CHEK2, ESR1
10MP:00107719.2ATM, BRCA1, BRCA2, CCND1, ERBB2, ESR1
11MP:00020069.0ATM, BARD1, BRCA1, BRCA2, BRIP1, CCND1
12MP:00036318.9ATM, BARD1, BRCA1, BRCA2, BRIP1, CCND1
13MP:00053788.8ATM, BARD1, BRCA1, BRCA2, CCND1, ERBB2
14MP:00053848.8ATM, BARD1, BRCA1, BRCA2, BRIP1, CCND1
15MP:00053768.8ATM, BRCA1, BRCA2, BRIP1, CCND1, CHEK2
16MP:00107688.5ATM, BARD1, BRCA1, BRCA2, CCND1, CHEK2

Drugs & Therapeutics for Familial Breast Cancer

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Drugs for Familial Breast Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 380)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
BenzocaineapprovedPhase 4, Phase 318921994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
2tannic acidapproved, NutraceuticalPhase 4, Phase 31892
3Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 112767
4HormonesPhase 4, Phase 3, Phase 2, Phase 113979
5EstrogensPhase 4, Phase 3, Phase 2, Phase 12470
6Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 112778
7
DaidzeinPhase 412486-66-85281708
Synonyms:
4',7-Dihydroxy-Isoflavone
4',7-Dihydroxyisoflavone
 
7,4'-Dihydroxyisoflavone
7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Daidzeol
Isoaurostatin
8PhytoestrogensPhase 492
9Dermatologic AgentsPhase 4, Phase 3, Phase 1, Phase 25674
10Soy BeanNutraceuticalPhase 4535
11
CarboplatinapprovedPhase 3, Phase 2, Phase 1198041575-94-410339178, 498142, 38904
Synonyms:
(SP-4-2)-diammine[cyclobutane-1,1-dicarboxylato(2-)-kappa(2)O,O']platinum
/h1-3H2,(H,7,8)(H,9,10)
/q
1,1-Cyclobutanedicarboxylate diammine platinum (II)
1,1-Cyclobutanedicarboxylate diammine platinum(II)
2*-1
2*1H2
41575-94-4
70903-55-8
AC-1457
AC1L8I6U
Ambap41575-94-4
BSPBio_003145
C 2538
C2043
C2538_SIGMA
C6H10N2O4Pt
CBDCA
CCRIS 3404
CHEBI:31355
CHEMBL1351
CHEMBL288376
CID10339178
CID2567
CID38904
CID426756
CID498142
CID5352133
CID6398587
CID6603770
Carbopaltin
Carboplatin
Carboplatin (JAN/USP/INN)
Carboplatin (USAN)
Carboplatin [USAN:INN:BAN:JAN]
Carboplatine
Carboplatine [French]
Carboplatino
Carboplatino [Spanish]
Carboplatinum
Carboplatinum [Latin]
Cbdca
Cyclobutane-1,1-dicarboxylate
D01363
DB00958
Diammine(1,1-cyclobutanedicarboxylato)platinum (II)
Diammine(cyclobutane-1,1-dicarboxylato(2-)-O,O')platinum
Diammine-1,1-cyclobutane dicarboxylate platinum II
DivK1c_000892
EINECS 255-446-0
EU-0100230
Ercar
HMS1921J16
HMS2090M05
HMS2092B22
HMS502M14
HSDB 6957
I14-2390
IDI1_000892
IUPAC: Azane
InChI=1/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6
 
JM 8
JM-8
KBio1_000892
KBio2_002009
KBio2_004577
KBio2_007145
KBio3_002645
KBioGR_000713
KBioSS_002009
LS-117689
Lopac-C-2538
Lopac0_000230
MolPort-003-665-501
MolPort-003-845-609
NCGC00015223-01
NCGC00093695-01
NCGC00094961-01
NCGC00094961-02
NCGC00094961-03
NCGC00162099-01
NCGC00162099-02
NCGC00167800-01
NCGC00178242-01
NINDS_000892
NSC 201345
NSC 241240
NSC-241240
NSC201345
NSC241240
Paraplatin
Paraplatin (TN)
Paraplatin, Carboplatin
Paraplatin-AQ
Platinum(+2) Cation
Platinum(II), (1, 1-cyclobutanedicar
Platinum, diammine(1,1-cyclobutanedicarboxylato(2-)-O,O')-, (SP-4-2)
Platinum, {diammine[1,1-cyclobut
S1215_Selleck
SPBio_000716
SPECTRUM1502106
Spectrum2_000898
Spectrum3_001503
Spectrum4_000337
Spectrum5_001094
Spectrum_001529
UNII-BG3F62OND5
azanide
carboplatin
cis -Diammine[1,1-cyclobutane-dicarboxylato] platinum
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II)
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(ii)
cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II)
cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II)
cis-Diammine(1,1-cyclobutanedicarboxylato) platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
cis-Diammine(cyclobutanedicarboxylato)platinum II
cyclobutane-1,1-dicarboxylic acid
diammine[cyclobutane-1,1-dicarboxylato(2-)-k2O1,O1]platinum
nchembio.573-comp10
nchembio773-comp2
nchembio873-comp3
platinum(2+)
12
VidarabineapprovedPhase 3, Phase 251224356-66-932326, 21704
Synonyms:
(+)-Cyclaradine
.beta.-Adenosine
.beta.-D-Adenosine
1odi
2-(6-AMINO-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
2946-52-3
2fqy
2gl0
30143-02-3
3080-29-3
3228-71-5
4005-33-8
46946-45-6
46969-16-8
524-69-6
5536-17-4
58-61-7
9-Arabinosyladenine
9-beta-D-Arabinofuranosyl-9H-purin-6-amine
9-beta-D-Arabinofuranosyl-adenine
9-beta-D-Arabinofuranosyladenine
9-beta-D-arabinofuranosyl-adenine
9-β-D-arabinofuranosyl-9H-purin-6-amine
9-β-D-arabinofuranosyladenine
A 9251
A0152
A4036_SIGMA
A4676_SIGMA
A5762_SIGMA
A9251_SIGMA
AC1L18OL
AC1L1U8O
AC1L2IWM
AC1L2SCM
AC1O4WIN
AC1O8PY7
AC1Q1ID3
AC1Q4Y1Z
AC1Q52XU
ADENOSINE, U.S.P.
ADN
AI3-52413
AI3-52821
AR-1H6029
ARA-A NSC 247519
Ade-Rib
Adenine Arabinoside
Adenine arabinoside
Adenine nucleoside
Adenine riboside
Adenine xyloside
Adenocard
Adenocard (TN)
Adenocard, Adenosine
Adenocor
Adenoscan
Adenoscan (TN)
Adenosin
Adenosin [German]
Adenosine (JAN/USP)
Adenosine [USAN:BAN]
Adenosine arabinose
Adenosine-8-14C
Adensoine
Ambap5536-17-4
Ara A
Ara-A
Ara-ATP
Araadenosine
Arabinoside Adenine
Arabinoside adenine
Arabinosyl Adenine
Arabinosyl adenine
Arabinosyl-adenine
Arabinosyladenine
Arasena-A
Armes
Armes (TN)
BB_NC-0565
BPBio1_000898
BRN 0624881
BSPBio_000816
BSPBio_001796
BSPBio_002000
Bio1_000437
Bio1_000926
Bio1_001415
Boniton
C00212
CAS-5536-17-4
CCRIS 2557
CCRIS 3383
CHEBI:136932
CHEBI:16335
CHEBI:45327
CHEMBL1090
CHEMBL20247
CHEMBL477
CI 673
CI-673
CID102198
CID191
CID21704
CID60961
CID6420052
CID6713976
CPD000471872
Caswell No. 010B
D000241
D00045
D06298
DB00640
DivK1c_000191
EINECS 200-389-9
EINECS 217-911-6
EINECS 226-893-9
EU-0100123
FT-0082881
HMS1570I18
HMS1920A13
HMS1921K05
HMS2090F06
HMS2091G13
HMS2092C16
HMS500J13
HSDB 6514
 
I01-1121
IDI1_000191
KBio1_000191
KBio2_002418
KBio2_004986
KBio2_007554
KBio3_001296
KBio3_001500
KBioGR_001224
KBioSS_002424
L000094
LS-15059
LS-15085
Lopac0_000123
MEDR-640
MLS000069638
MLS000699527
MLS001066352
MLS001333133
MLS001333134
MLS002153227
MLS002153992
MolPort-001-785-903
MolPort-001-838-229
MolPort-003-666-308
Myocol
NCGC00016656-01
NCGC00023673-03
NCGC00023673-04
NCGC00023673-05
NCGC00023673-06
NCGC00023673-07
NCGC00094579-01
NCGC00094579-02
NCGC00094579-03
NCGC00094579-04
NCGC00178869-01
NCGC00179417-01
NCI60_003823
NCI60_037192
NCIOpen2_003303
NCIOpen2_005376
NINDS_000191
NSC 247519
NSC 404241
NSC 627048
NSC 7359
NSC 7652
NSC-404241
NSC247519
NSC404241
NSC627048
NSC70422
NSC7359
NSC7652
NSC80832
NSC87676
NSC91041
Nucleocardyl
PDSP1_001036
PDSP2_001020
Pallacor
Polyadenosine
Polyriboadenosine
Prestwick0_000768
Prestwick1_000768
Prestwick2_000768
Prestwick3_000768
Prestwick_983
RAB
S1647_Selleck
S1784_Selleck
SAM002564191
SMP1_000312
SMR000058216
SMR000225041
SMR000471872
SMR001233326
SPBio_001194
SPBio_001491
SPBio_002755
SPECTRUM1500107
SPECTRUM1500609
SR 96225
SR-96225
STK361815
SUN-Y4001
Sandesin
Spectrum2_001257
Spectrum2_001336
Spectrum3_000288
Spectrum3_000580
Spectrum4_000782
Spectrum5_001429
Spectrum_001894
Spongoadenosine
TL8003749
UNII-3XQD2MEW34
UNII-K72T3FS567
USAF CB-10
V0098
VIRDARABINE
Vidarabin
Vidarabina
Vidarabina [DCIT]
Vidarabine
Vidarabine (JAN)
Vidarabine anhydrous
Vidarabinum
Vira ATM
Vira-A
Vira-A, Vidarabine
XA
Xylosyl A
Xylosyladenine
ZINC00970363
ZINC02169830
adenine-D-ribose
adenosine
alpha-Ara A
beta-Adenosine
beta-Ara A
beta-D-Adenosine
bmse000061
nchembio.143-comp9
nchembio.186-comp109
nchembio.64-comp4
nchembio706-5
13
Vorinostatapproved, investigationalPhase 3, Phase 1, Phase 2242149647-78-95311
Synonyms:
149647-78-9
1zz1
AC-1923
AC1L1K2K
BRD-K81418486-001-10-3
C111237
CCRIS 8456
CHEBI:45716
CHEMBL98
CID5311
D06320
DB02546
EC-000.2057
FT-0082592
LS-186548
LS-186997
LS-187780
MK-0683
MK0683
MLS001065855
Merck brand of Vorinostat
MolPort-003-850-293
N'-hydroxy-N-phenyloctanediamide
N-Hydroxy-N'-phenyl octanediamide
N-Hydroxy-N'-phenyloctanediamide
N-Hyrdroxy-N'-phenyloctanediamide
N-hydroxy-N'-phenyl-octane-1,8-diotic acid diamide
N-hydroxy-N'-phenyloctanediamide
N1-hydroxy-N8-phenyloctanediamide
NCGC00168085-02
 
NHNPODA
NSC-701852
NSC701852
OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE
Octanedioic acid hydroxyamide phenylamide
S1047_Selleck
SAHA
SAHA cpd
SAHA, Suberoylanilide hydroxamic acid
SHH
SKI390
SMR000486344
SW-064652
Suberanilohydroxamic acid
SuberoylaN/Aide hydroxamic acid
Suberoylanilide hydroxamic acid
UNII-58IFB293JI
Vorinostat
Vorinostat (JAN/USAN)
Vorinostat MSD
Vorinostat [USAN]
Vorinostatum
WIN64652
ZINC01543873
Zolinza
Zolinza (TN)
Zolinza, MK-0683, SAHA
m344
nchembio.275-comp2
nchembio.313-comp1
nchembio815-comp18
suberoylanilide hydroxamic acid
14
FludarabineapprovedPhase 3, Phase 2111321679-14-1, 75607-67-930751
Synonyms:
(2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
(2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
2-F-ARAA
2-F-ara-A
2-Fluoro Ara-A
2-Fluoro-9-beta-D-arabinofuranosyladenine
2-fluoro ARA-A
21679-14-1
9-beta-D-Arabinofuranosyl-2-fluoroadenine
9-beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine
9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro- (9CI)
AC1LCW8I
AC1Q51CF
C10H12FN5O4
CCRIS 3382
CHEMBL1568
CID657237
CPD000058874
D07966
EINECS 244-525-5
F-Ara-A
FAMP
FT-0082766
FaraA
Fludara
Fludara, Fludarabine
 
Fludarabina
Fludarabina [Spanish]
Fludarabine
Fludarabine (INN)
Fludarabine 5'-monophosphate
Fludarabine [INN]
Fludarabine monophosphate
Fludarabine phosphate
Fludarabinum
Fludarabinum [Latin]
Fludura
Fluradosa
Fluradosa (TN)
HSDB 6964
I14-4978
LS-15061
MLS000028687
NSC 118218
NSC 118218H
NSC-118218
S1491_Selleck
SAM002548956
SMR000058874
SQ Fludarabine
UNII-1X9VK9O1SC
UNII-P2K93U8740
ZINC04216238
15
Cyclophosphamideapproved, investigationalPhase 3, Phase 2, Phase 1282950-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Anhydrous cyclophosphamide
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
 
DB00531
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
16
rituximabapprovedPhase 3, Phase 2, Phase 11654174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
17
Zoledronic acidapprovedPhase 3290118072-93-868740
Synonyms:
(1-Hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid
(1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid
(1-hydroxy-2-imidazol-1-yl-1-phosphonoethyl)phosphonic acid
(1-hydroxy-2-imidazol-1-yl-phosphonoethyl)phosphonic acid monohydrate
(1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid
118072-93-8
2-(imidazol-1-yl)-1-hydroxyethane-1,1-diphosphonic acid
2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosphonic acid
AC-1092
AC1L2ACJ
AC1Q6RN3
AKOS005145739
Aclasta
Anhydrous Zoledronic Acid
BIDD:GT0292
BIDD:PXR0134
Bio-0112
Bisphosphonate 3
C088658
CGP 42'446
CGP 42446
CGP 42446A
CGP-42'446
CGP-42446
CHEBI:46557
CHEMBL924
CID68740
D08689
DB00399
 
FT-0082657
HMS2089O09
I06-0710
KS-1132
LS-181815
MolPort-002-885-874
MolPort-003-850-890
NCGC00159521-02
NCGC00159521-03
NSC721517
Novartis brand of zoledronic acid
Reclast
Reclast (TN)
S00092
S1314_Selleck
UNII-70HZ18PH24
ZOL
Zol
Zoledronate
Zoledronic Acid Anhydrous
Zoledronic Acid, Anhydrous
Zoledronic acid
Zoledronic acid (INN)
Zoledronic acid [USAN:INN]
Zometa
Zometa (Novartis)
Zometa (TN)
Zometa Concentrate
Zometa, Zomera, Aclasta and Reclast, Zoledronic Acid
[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid)
18
PancrelipaseapprovedPhase 3, Phase 293553608-75-6
Synonyms:
1,4-alpha-D- glucan glucanohydrolase
PA
 
Pancreatic alpha-amylase precursor
Pancrelipase (amylase
lipase
protease)
19
Paclitaxelapproved, vet_approvedPhase 3, Phase 2, Phase 1275833069-62-436314
Synonyms:
(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester
12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
157069-30-2
33069-62-4
5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.
7-Epi-Paclitaxel
7-Epi-Taxol
7-Epipaclitaxel
7-Epitaxol
7-epi-Paclitaxel
7-epi-Taxol
AB00513812
ABI 007
ABI-007
ABI007
AC-675
AC1L1IOG
AC1L1VJI
AC1L9AVF
ACon1_002231
ANX-513
Abraxane
Abraxane (TN)
Abraxane I.V. Suspension
Abraxis BioScience brand of albumin-bound paclitaxel
Ambotz33069-62-4
Anzatax
Asotax
BIDD:PXR0046
BMS 181339-01
BMS-181339
BMS-181339-01
BPBio1_000320
BRD-A23723433-001-01-2
BRD-A28746609-001-04-0
BRD-K62008436-001-03-1
BSPBio_000290
BSPBio_001152
BSPBio_002614
Bio-0076
Bio1_000362
Bio1_000851
Bio1_001340
Bio2_000416
Bio2_000896
Bristaxol
C07394
C466458
C47H51NO14
CCRIS 8143
CHEBI:103439
CHEBI:45863
CHEMBL100910
CHEMBL418410
CHEMBL48
CID36314
CID441276
CID4666
CID6713921
CID6915727
CPD-8718
Capxol
D00491
DB01229
DHP-107
DHP-208
DRG-0190
DTS-301
DivK1c_000441
EU-0101201
Ebetaxel
EmPAC
Epitaxol
Genaxol
Genetaxyl
Genexol
Genexol-PM
HMS1362J13
HMS1568O12
HMS1792J13
HMS1922K08
HMS1990J13
HMS2090D07
HMS2093K15
HMS501G03
HSDB 6839
I06-0014
IDI1_000441
IDI1_002171
Intaxel
KBio1_000441
KBio2_000492
KBio2_002016
KBio2_002509
KBio2_003060
KBio2_004584
KBio2_005077
KBio2_005628
KBio2_007152
KBio2_007645
KBio3_000903
KBio3_000904
KBio3_001834
KBio3_002987
KBioGR_000492
KBioGR_001893
 
KBioGR_002509
KBioSS_000492
KBioSS_002016
KBioSS_002517
LMPR0104390001
LS-31070
LipoPac
Lopac0_001201
MBT 0206
MEGxp0_001940
MLS000863266
MLS001077297
MLS002154218
MLS002172439
MLS002695976
MPI-5018
Micellar Paclitaxel
Mitotax
MolPort-001-742-627
MolPort-003-665-783
MolPort-003-932-365
NCGC00024995-02
NCGC00024995-03
NCGC00024995-04
NCGC00024995-05
NCGC00024995-06
NCGC00024995-07
NCGC00164367-01
NCGC00164367-02
NCGC00164367-03
NCI60_000601
NINDS_000441
NK 105
NP-010981
NSC 125973
NSC-125973
NSC125973
NSC358882
Nanotaxel
Neuro_000060
Nova-12005
OAS-PAC-100
OncoGel
Onxal
Onxol
Onxol, Taxol, Nov-Onxol, Paclitaxel
P1632
Paclical
Pacligel
Paclitaxel
Paclitaxel (JAN/USP)
Paclitaxel (JAN/USP/INN)
Paclitaxel (Taxol)
Paclitaxel [USAN:INN:BAN]
Paxceed
Paxene
Paxoral
Plaxicel
Praxel
Prestwick0_000155
Prestwick1_000155
Prestwick2_000155
Prestwick3_000155
Probes2_000350
QW 8184
S-8184 Paclitaxel Injectable Emulsion
S1150_Selleck
SDCCGMLS-0066823.P001
SDP-013
SMP1_000228
SMR000394086
SMR000857385
SPBio_000943
SPBio_002229
SPECTRUM1503908
ST50306996
Spectrum2_000872
Spectrum3_001057
Spectrum4_001197
Spectrum5_001491
Spectrum_001536
T 7402
T1912_SIGMA
T7191_SIGMA
T7402_SIGMA
TA1
TAXOL (TN)
TAXOL, 10-EPI,
TXL
TaxAlbin
Taxol
Taxol A
Taxol Konzentrat
Taxol.RTM. (Registered Trademark)
UNII-P88XT4IS4D
UPCMLD-DP108:001
UPCMLD-DP108:002
Vascular Wrap
Xorane
Yewtaxan
abi-007
albumin-bound paclitaxel
cMAP_000068
nab-paclitaxel
nchembio.188-comp1
nchembio.2007.34-comp9
nchembio.215-comp9
nchembio853-comp6
paclitaxel
weekly paclitaxel
20
MechlorethamineapprovedPhase 3, Phase 237751-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
 
KBioGR_001448
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine
21
IfosfamideapprovedPhase 3, Phase 23913778-73-23690
Synonyms:
(+-)-Ifosfamid
(+-)-Ifosphamide
(+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
(D,L)-Ifosfamide
(R,S)-Ifosphamide
(R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd
2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI)
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
3,} 2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
36341-88-5
3778-73-2
84711-20-6
A 4942
AB00513932
AC-2113
AC1L1GHW
ASTA Z 4942
Ambap3778-73-2
Asta Z 4942
BPBio1_000865
BRN 0611835
BSPBio_000785
C07047
CAS-3778-73-2
CCRIS 352
CHEBI:5864
CHEMBL1024
CID3690
Cyfos
D00343
D007069
DB01181
EINECS 223-237-3
HMS1570H07
HMS2090M12
HMS2093N07
HSDB 7023
Holoxan
Holoxan 1000
I-Phosphamide
I06-0494
IFEX (TN)
Ifex
Ifosfamid
Ifosfamida
Ifosfamida [INN-Spanish]
Ifosfamide (JAN/USP/INN)
 
Ifosfamide Sterile
Ifosfamide [USAN:INN:BAN:JAN]
Ifosfamidum
Ifosfamidum [INN-Latin]
Ifosphamide
Ifsofamide
Iphosphamid
Iphosphamid(e)
Iphosphamide
Iso Endoxan
Iso-Endoxan
Isoendoxan
Isofosfamide
Isophosphamide
Isosfamide
LS-102
LS-99799
MJF 9325
MJF-9325
MLS002154021
Mitoxana
Mitoxana, Ifex, Ifosfamide
MolPort-003-666-704
N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide
N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine
NCGC00016639-01
NCGC00179435-01
NCI-C01638
NCI60_000233
NPFAPI-04
NSC 109,724
NSC 109724
NSC-109,724
NSC-109724
NSC109,724
NSC109724
Naxamide
Prestwick0_000833
Prestwick1_000833
Prestwick2_000833
Prestwick3_000833
S1302_Selleck
SMR001233348
SPBio_002706
STL058690
UNII-UM20QQM95Y
WLN: T6NPOTJ AM2G BO B2G
Z 4942
Z-4942
Z4942
ifosfamide
isosfamide
{3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,
22
Progesteroneapproved, vet_approvedPhase 3, Phase 2, Phase 153757-83-05994
Synonyms:
(S)-4-Pregnene-3,20-dione
(S)-Pregn-4-en-3,20-dione
(S)-Progesterone
.beta.-Progesterone
.delta.(sup4)-Pregnene-3,20-dione
.delta.4-Pregnene-3,20-dione
17.alpha.-Progesterone
17a-Progesterone
17alpha-Progesterone
17alpha-progesterone
17α-progesterone
1dbb
1h60
257630-50-5
3,20-Pregnene-4
32104FB6-BF81-4F6E-83C2-024DEEAEB272
4-Pregnen-3,20-dione
4-Pregnene-3,20-dione
46665_FLUKA
46665_RIEDEL
57-83-0
753497-20-0
8012-32-6
8023-13-0
AC-700
AC1L1LKF
AI3-51682
Agolutin
Akrolutin
BB_NC-0185
BHR-100
BIDD:ER0547
BIDD:PXR0094
BPBio1_000676
BRD-K64994968-001-03-6
BSPBio_000614
Bio-luton
C00410
CCRIS 533
CHEBI:17026
CHEMBL103
CID5994
CIDR
CMC_13406
COL-1620
CPD000058345
Colprosterone
Corlutin
Corlutina
Corluvite
Corporin
Corpus Luteum Hormone
Corpus luteum hormone
Crinone
Crinone (TN)
Crinone progesterone gel
Curretab
Cyclogest
Cyclogesterin
D00066
D4-Pregnene-3,20-dione
DB00396
DR-2011
Delalutin
Delta(4)-pregnene-3,20-dione
Duraprogen
EINECS 200-350-6
ETI-411
EU-0100895
Endometrin
Estima
FE-999913
Flavolutan
Fologenon
Gelbkoerperhormon
Gesterol
Gesterol 100
Gesterol 50
Gestiron
Gestone
Gestormone
Gestron
Glanducorpin
Gynlutin
Gynoluton
Gynolutone
HMS1569O16
HMS2051O05
HMS2090J07
HSDB 3389
Hormoflaveine
Hormoluton
Hydroxyprogesterone Caproate
Hydroxyprogesterone Caproic acid
LMST02030159
LS-234
Lingusorbs
Lipo-Lutin
Lipolutin
Lopac0_000895
Lucorteum
Lucorteum Sol
Lucorteum sol
Lugesteron
Luteal hormone
Luteinique
Luteocrin normale
Luteodyn
Luteogan
Luteohormone
Luteol
Luteol (VAN)
Luteopur
Luteosan
Luteostab
Luteovis
Luteum
Lutex
Lutidon
Lutin
Lutinus
Lutociclina
Lutocuclin M
Lutocyclin
Lutocyclin M
 
Lutocyclin m
Lutocylin
Lutocylol
Lutoform
Lutogyl
Lutogynon
Lutren
Lutromone
MLS000028517
MLS000758277
MLS001074187
MLS002222367
MPA
Membrettes
Methylpregnone
Micronized Progesterone
MolPort-001-794-643
NCGC00022185-03
NCGC00022185-04
NCGC00022185-05
NCGC00022185-06
NCGC00022185-07
NCGC00022185-08
NCGC00022185-09
NCGC00090798-01
NCGC00090798-02
NCI60_042166
NSC 64377
NSC 9704
NSC-9704
NSC64377
NSC9704
Nalutron
Natural Progesterone
P 0130
P0130_SIGMA
P0478
P3972_SIGMA
P6149_SIGMA
P7556_ALDRICH
P7556_SIGMA
P8783_SIGMA
P9776_SIGMA
PROGESTERONE
Percutacrine
Percutacrine Luteinique
Piaponon
Pranone
Pregn-4-en-3,20-dione
Pregn-4-ene-3,20-dione
Pregnene-3,20-dione
Pregnenedione
Prestwick0_000477
Prestwick1_000477
Prestwick2_000477
Prestwick3_000477
Prestwick_411
Primolut
Prochieve
Progeffik
Progekan
Progestan
Progestasert
Progesterol
Progesteron
Progesterona
Progesterona [INN-Spanish]
Progesterone
Progesterone (JP15/USP/INN)
Progesterone [INN:BAN:JAN]
Progesterone [Progestins]
Progesterone, water-soluble
Progesterone-Water Soluble
Progesterone: HBC complex
Progesteronum
Progesteronum [INN-Latin]
Progestin
Progestogel
Progestol
Progeston
Progestone
Progestosol
Progestrel
Progestron
Progestronol
Progestérone
Projestaject
Prolets
Prolidon
Prolutin
Proluton
Prolutone
Prometrium
Prometrium (TN)
Prontogest
Protormone
S00293
S1705_Selleck
SAM001247039
SMR000058345
SMR000653542
SPBio_002553
SR-01000000088
SR-01000000088-5
Spectrum5_002053
Syngesterone
Syngestrets
Synovex S
Syntolutan
U 3672
UNII-4G7DS2Q64Y
Utrogest
Utrogestan
Vitarrine
WLN: L E5 B666 OV MUTJ A1 E1 FV1
ZINC04428529
beta-Progesterone
bmse000482
component of Cyclogesterin
corpus luteum hormone
delta(4)-Pregnene-3,20-dione
delta(Sup 4)-Pregnene-3,20-dione
delta(Sup4)-pregnene-3,20-dione
delta(sup 4)-Pregnene-3,20-dione
delta4-Pregnene-3,20-dione
luteohormone
nchembio.2007.53-comp14
23
Estradiolapproved, investigational, vet_approvedPhase 3, Phase 2, Phase 1128350-28-25757, 53477783
Synonyms:
(+)-3,17b-Estradiol
(17b)-Estra-1,3,5(10)-triene-3,17-diol
(17beta)-Estra-1,3,5(10)-triene-3,17-diol
.alpha.-Estradiol
.alpha.-Oestradiol
.beta.-Estradiol
.beta.-Oestradiol
1,3,5[10]-Estratriene-3,17beta-diol 3-sulfate
1,3,5[10]-Estratriene-3,17beta-diol 3-sulphate
13b-Methyl-1,3,5(10)-gonatriene-3,17b-ol
17 beta-Estradiol
17-.BETA.-Estradiol
17-E
17-beta
17-beta-OH-estradiol
17-beta-estradiol
17.beta.-Estradiol
17.beta.-Oestradiol
17E
17b-Estradiol
17b-Oestradiol
17beta Oestradiol
17beta oestradiol
17beta-Estra-1,3,5(10)-triene-3,17-diol
17beta-Estradiol
17beta-Oestradiol
1jgl
1qkt
1qku
2d06
3,17-Epidihydroxyestratriene
3,17-beta-Estradiol
3,17-beta-Oestradiol
3,17.beta.-Estradiol
3,17b-Dihydroxyestra-1,3,5(10)-triene
3,17b-Estradiol
3,17beta-Estradiol
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulfate
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulphate
50-28-2
73459-61-7
873662-39-6
AC-10460
AC1L1L2K
Aerodiol
Agofollin
Alora
Altrad
Amnestrogen
Aquadiol
B-Estradiol
BEDOs
BIDD:ER0125
BIDD:PXR0065
BPBio1_000532
BSPBio_000482
BSPBio_001065
Bardiol
Benzhormovarine
Beta-estradiol
Bio-0812
Bio-E-Gel
Bio1_000403
Bio1_000892
Bio1_001381
Bio2_000363
Bio2_000843
C00951
C18H24O2
CCRIS 280
CHEBI:16469
CHEMBL135
CID5757
CMC_11154
CPD-352
CPD000059126
Climaderm
Climara
Climara (TN)
Climara Forte
Compudose
Compudose 200
Compudose 365
Corpagen
D-3,17beta-Estradiol
D-Estradiol
D-Oestradiol
D00105
DB00783
Dermestril
Destradiol
Dihydro-Theelin
Dihydrofollicular hormone
Dihydrofolliculin
Dihydromenformon
Dihydrotheelin
Dihydroxyesterin
Dihydroxyestrin
Dihydroxyoestrin
Dimenformon
Diogyn
Diogynets
Divigel
Divigel (TN)
E 2
E 8875
E(sub 2)
E0025
E1024_SIGMA
E1132_SIGMA
E2257_SIGMA
E2758_SIGMA
E8875_SIGMA
EINECS 200-023-8
EU-0100503
Elestrin
Encore
Epiestriol 50
Esclim
Estra-1,3,5(10)-triene-3,17b-diol
Estrace
Estrace (TN)
Estraderm
Estraderm (TN)
Estraderm MX
Estraderm TTS
Estraderm TTS 100
Estraderm TTS 50
Estradiol
Estradiol [USAN:INN]
Estradiol-17 beta
Estradiol-17-beta
Estradiol-17.beta.
Estradiol-17beta
Estradiol-3,17beta
Estradiolo
Estradiolo [DCIT]
Estradiolum
Estradiolum [INN]
Estradot
Estraldine
Estrapak 50
Estrasorb
Estrasorb (TN)
Estreva
Estrifam
Estring
Estring (TN)
Estring Vaginal Ring
Estring vaginal ring
Estroclim
Estroclim 50
Estrodiolum
Estrofem 2
Estrofem Forte
Estrogel
 
Estrogel (TN)
Estrogel HBF
Estrovite
Evamist
Evorel
Extrasorb
Femanest
Femestral
Femestrol
Femogen
Fempatch
Femtrace
Femtran
Follicyclin
Gelestra
Ginedisc
Ginosedol
GynPolar
Gynergon
Gynestrel
Gynodiol
Gynoestryl
HMS1362E07
HMS1569I04
HMS1792E07
HMS1990E07
HMS2051C17
HMS2090E18
HSDB 3589
IDI1_002118
Innofem
Innofem (TN)
KBio2_000405
KBio2_002269
KBio2_002973
KBio2_004837
KBio2_005541
KBio2_007405
KBio3_000769
KBio3_000770
KBio3_002749
KBioGR_000405
KBioGR_002269
KBioSS_000405
KBioSS_002270
LMST02010001
LS-137
Lamdiol
Lio-Oid
Lopac0_000503
MLS000069494
MLS000758312
MLS001076331
Macrodiol
Macrol
Menest
Menorest
Menostar
Microdiol
MolPort-001-794-632
NCGC00091544-00
NCGC00091544-01
NCGC00091544-02
NCGC00091544-04
NCGC00091544-05
NCGC00091544-06
NCGC00091544-07
NCGC00091544-08
NCGC00091544-09
NCGC00091544-12
NCGC00179321-01
NCGC00179321-02
NSC-9895
NSC9895
Nordicol
Oesclim
Oestergon
Oestra-1,3,5(10)-triene-3,17b-diol
Oestradiol
Oestradiol Berco
Oestradiol R
Oestradiol-17-beta
Oestradiol-17.beta.
Oestradiol-17beta
Oestradiolum
Oestrogel
Oestroglandol
Oestrogynal
Ovahormon
Ovasterol
Ovastevol
Ovociclina
Ovocyclin
Ovocycline
Ovocylin
Perlatanol
Polyestradiol
Prestwick0_000441
Prestwick1_000441
Prestwick2_000441
Prestwick3_000441
Prestwick_207
Primofol
Profoliol
Profoliol B
Progynon
Progynon DH
Progynon-DH
S-21400
S1709_Selleck
SAM001247032
SK-Estrogens
SL-1100
SMP1_000121
SMR000059126
SPBio_002421
Sandrena 1
Sandrena Gel
Sisare Gel
Spectrum5_002055
Syndiol
Systen
Tradelia
Trial SAT
Trocosone
UNII-4TI98Z838E
VIVELLE-DOT
Vagifem
Vagifem (TN)
Vivelle
Vivelle (TN)
Zerella
Zesteem
Zesteen
Zumenon
[2,4,6,7-3H]-E2
[3H]-estradiol
[3H]]estradiol
b-Estradiol
beta-Estradiol
beta-Estradiol 3-sulfate
beta-Estradiol 3-sulphate
bmse000642
cMAP_000005
cis-Estradiol
cis-Oestradiol
component of Menrium
delta-Estradiol
delta-Oestradiol
estradiol
estradiol-17beta
nchembio.168-comp3
nchembio.76-comp2
nchembio775-comp2
nchembio794-comp6
nchembio860-comp1
progynon
24
CetuximabapprovedPhase 3, Phase 2737205923-56-456842117, 2333
Synonyms:
205923-56-4
Anti EGFR
Cetuximab
Cetuximab (USAN/INN)
Cetuximab (genetical recombination)
Cetuximab (genetical recombination) (JAN)
 
Cetuximabum
Cétuximab
D03455
Erbitux
Erbitux (TN)
IMC-C225
Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer
cetuximab
25
Anastrozoleapproved, investigationalPhase 3, Phase 2272120511-73-12187
Synonyms:
.alpha.,alpha.,.alpha.',.alpha.'-tetramethyl-5(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
1,3-benzenediacetonitrile, a, a, a', a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)
120511-73-1
2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
AC-4234
AC1L1D49
Anastrazole
Anastrole
Anastrozol
Anastrozole (JAN/USAN/INN)
Anastrozole [USAN:INN:BAN]
Arimidex
Arimidex (TN)
Arimidex (Zeneca)
Arimidex, Anastrozole
Asiolex
Astra brand of anastrozole
AstraZeneca brand of anastrozole
C08159
C090450
C17H19N5
CHEBI:2704
CHEMBL1399
CID2187
CPD000466301
 
D00960
DB01217
HMS2052M11
HMS2089N10
HSDB 7462
I06-0021
ICI D1033
ICI-D 1033
ICI-D1033
LS-29563
MLS000759396
MLS001424217
MolPort-005-933-078
NCGC00164619-01
NSC719344
S1188_Selleck
SAM001246525
SBB066057
SMR000466301
UNII-2Z07MYW1AZ
ZD 1033
ZD-1033
ZD1033
ZINC00000941
Zeneca ZD 1033
Zeneca brand of anastrozole
alpha,alpha,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
anastrazole
anastrozole
26
Capecitabineapproved, investigationalPhase 3, Phase 21296154361-50-960953
Synonyms:
(1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-carbamic acid pentyl ester
154361-50-9
158798-73-3
5'-Deoxy-5-fluoro-N-((pentyloxy)carbonyl)cytidine
5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine
AC1L1U83
AC1Q4KU8
Ambap154361-50-9
C110904
C12650
C15H22FN3O6
CAPE
CAPECITABINE
CHEBI:31348
CHEMBL1773
CID60953
Capecitabin
Capecitabina
Capecitabine (JAN/USAN/INN)
Capecitabine [USAN]
Capecitabinum
Capecitibine
Capiibine
Carbamic acid, (1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-, pentyl ester
Caxeta
 
D01223
DB01101
FT-0082472
HSDB 7656
LS-59070
MolPort-005-938-254
N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine
Pentyl 1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate
Pentyl [1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate
R-340
R340
RG-340
Ro 09-1978
Ro 09-1978/000
Ro-09-1978
Ro-09-1978/000
S1156_Selleck
UNII-6804DJ8Z9U
Xabine
Xeloda
Xeloda (TN)
Xeloda, Captabin, Capecitabine
ZINC03806413
capecitabina
capecitabine
capecitabinum
pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate
27
LenalidomideapprovedPhase 3, Phase 2, Phase 1718191732-72-6216326
Synonyms:
1-oxo-2-(2,6-Dioxopiperidin-3-yl)-4-aminoisoindoline
191732-72-6
3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
3-(7-Amino-3-oxo-1H-isoindol-2-yl)-piperidine-2,6-dione
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
346670-73-3
443912-14-9
AC-914
AC1L50II
AKOS005146276
ALBB-015321
Bio-0168
C467567
CC 5013
CC-5013
CC-5013, Revlimid, Lenalidomide
CC5013
CDC 501
CDC-501
CDC-5013
CHEMBL848
CID216326
Celgene brand of lenalidomide
D04687
 
DB00480
EC-000.2340
ENMD-0997
I06-0831
IMID-1
IMID-5013
IMiD3
IMiD3 cpd
IMid-1
LS-184040
Lenalidomide
Lenalidomide (USAN/INN)
Lenalidomide [USAN]
MolPort-003-848-370
NCGC00167491-01
NSC747972
Revamid
Revimid
Revlimid
Revlimid (Celgene)
Revlimid (TN)
S1029_Selleck
STK639603
Thalidomide analog CC-5013
UNII-F0P408N6V4
lenalidomide
28
TamoxifenapprovedPhase 3, Phase 238010540-29-12733526
Synonyms:
(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine
(Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine (IUPAC)
(Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE
(Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
,citrate
1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-p-.beta.-Dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
10540-29-1
1ya4
2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
54965-24-1 (citrate)
AC1MBZ3R
Apo-Tamox
Apo-tamox
BIDD:ER0008
BIDD:GT0009
BIDD:PXR0003
BPBio1_000278
BRD-K93754473-001-02-9
BRD-K93754473-048-05-3
BSPBio_000252
BSPBio_001150
BSPBio_001982
C07108
C26H29NO
CCRIS 3275
CHEBI:41774
CHEMBL83
CID2733526
Citofen
Crisafeno
D08559
DB00675
Diemon
EINECS 234-118-0
Gen-Tamoxifen
Gen-tamoxifen
HMS1362J11
HMS1792J11
HMS1990J11
HMS2090N08
HSDB 6782
ICI 47699
ICI-46,474
ICI-47699
IDI1_000258
IDI1_002170
Istubol
Kessar
L024126
LS-393
Lopac0_001203
MLS001332535
MLS001332536
MolPort-003-850-384
 
NCGC00024928-01
NCGC00024928-03
NCGC00024928-04
NCGC00024928-05
NCGC00024928-07
NCGC00024928-08
NCGC00024928-09
NCGC00024928-12
NSC727681
Noltam
Nolvadex
Nolvadex-D
Nourytam
Novaldex
Novo-Tamoxifen
Oncomox
PMS-Tamoxifen
Pms-Tamoxifen
Prestwick2_000146
Prestwick3_000146
QTL1_000079
Retaxim
SMR000059172
ST50511785
Spectrum5_001417
Spectrum5_002043
T5648_SIGMA
TAMOXIFEN (TAMOXIFEN CITRATE (54965-24-1))
TRANS FORM OF TAMOXIFEN
Tamizam
Tamofen
Tamone
Tamoplex (TN)
Tamoxasta
Tamoxen
Tamoxifen
Tamoxifen (INN)
Tamoxifen (TN)
Tamoxifen (Z)
Tamoxifen Citrate
Tamoxifen [INN:BAN]
Tamoxifen and its salts
Tamoxifene
Tamoxifene [INN-French]
Tamoxifeno
Tamoxifeno [INN-Spanish]
Tamoxifenum
Tamoxifenum [INN-Latin]
Tamoxifène
Tocris-0999
Tomaxithen
Trans-Tamoxifen
UNII-094ZI81Y45
UPCMLD-DP027
Valodex
Zemide
cMAP_000044
nchembio.140-comp7
nchembio.76-comp1
nchembio732-comp3
tamoxifen
trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
trans-Tamoxifen
29
Fulvestrantapproved, investigationalPhase 3, Phase 2, Phase 1194129453-61-8104741, 17756771
Synonyms:
(7R,13S,17S)-13-methyl-7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
(7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
(7R,8S,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl) nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
(7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1,3,5(10)-triene-3,17-diol
129453-61-8
7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)estra-1,3,5(10)-triene-3,17-diol
7alpha-(9-((4,4,5,5,5,-Pentafluoropentyl)sulfinyl)nonyl)estra-1,3,5(10)-triene-3,17beta-diol
7alpha-(9-((4,4,5,5,5-Pentafluoropentyl)sulfinyl)nonyl)estra-1,3,5(10)-triene-3,17beta-diol
7alpha-[9[(4,4,5,5,5-Pentafluropentyl)sulfinyl]nonyl]-estra-1,3,5(10)-triene-3, 17 beta diol
AC-4693
AC1L2XEN
AstraZeneca brand of fulvestrant
BIDD:ER0348
BIDD:PXR0136
C070081
C32H47F5O3S
CCRIS 8741
CHEBI:404798
CHEMBL1358
CID104741
D01161
DB00947
Faslodex
Faslodex (TN)
 
Faslodex(ICI 182,780)
Faslodex, ICI 182780, Fulvestrant
Fulvestrant
Fulvestrant (JAN/USAN/INN)
Fulvestrant [USAN]
HMS2090N22
HSDB 7658
I06-1109
ICI 182,780
ICI 182,789
ICI-182780
Ici 182780
LS-64781
NCGC00164789-02
NSC719276
S1191_Selleck
UNII-22X328QOC4
ZD 182780
ZD-182780
ZD-9238
ZM 182780
ZM-182780
fulvestrant
nchembio.168-comp5
nchembio.76-comp5
nchembio775-comp4
30
PromethazineapprovedPhase 322560-87-74927
Synonyms:
(2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
(2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
(Dimethylamino-2-propyl-10-phenothiazine hydrochloride
10-(2-(Dimethylamino)-2-methylethyl)phenothiazine
10-(2-(Dimethylamino)propyl)phenothiazine
10-(2-Dimethylaminopropyl)phenothiazine
10-[2-(Dimethylamino)propyl]phenothiazine
10-[2-(dimethylamino)Propyl]phenothiazine
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl- (9CI)
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, radical ion(1+)
3277 RP
3389 R.p.
38878-40-9
4-27-00-01253 (Beilstein Handbook Reference)
4182 R.p.
60-87-7
73745-50-3
A-91033
AB00053535
AC-15939
AC1L1J92
Antiallersin
Aprobit
Avomine
BPBio1_000744
BRN 0088554
BSPBio_000676
BSPBio_002777
C07404
CCRIS 7056
CHEBI:8461
CHEMBL643
CID4927
Camergan
D00494
DB01069
Dimapp
Dimethylamino-isopropyl-phenthiazin
Dimethylamino-isopropyl-phenthiazin [German]
Diphergan
Diprazin
Diprazine
Diprozin
DivK1c_000005
EINECS 200-489-2
Fargan
Fenazil
Fenetazina
Fenetazine
Genphen
HMS2089E08
HSDB 3173
Hiberna
Histargan
IDI1_000005
Iergigan
InChI=1/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
Isophenergan
Isopromethazine
KBio1_000005
KBio2_001348
KBio2_003916
KBio2_006484
KBio3_001997
KBioGR_001697
KBioSS_001348
L000495
LS-264
Lercigan
Lergigan
Lilly 01516
Lilly 1516
Lopac0_000899
Metaryl
MolPort-001-783-684
N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine
N,N,α-trimethyl-10H-phenothiazine-10-ethanamine
N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine
 
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine hydrochloride
N-(2'-Dimethylamino-2'-methyl)ethylphenothiazine
N-(2'-dimethylamino-2'-Methyl)ethylphenothiazine
N-Dimethylamino-2-methylethyl thiodiphenylamine
NCGC00015817-10
NCGC00089735-02
NCGC00089735-03
NCI-C60673
NCI60_001878
NINDS_000005
NSC 30321
NSC30321
Oprea1_758749
PROMETHAZINE (SEE ALSO PROMETHAZINE HYDROCHLORIDE 58-33-3)
Pelpica
Phargan
Phenargan
Phenerzine
Phenoject-50
Phensedyl
Pilothia
Pilpophen
Pipolphene
Prestwick0_000888
Prestwick1_000888
Prestwick2_000888
Prestwick3_000888
Pro-50
Proazaimine
Proazamine
Procit
Promacot
Promazinamide
Promergan
Promesan
Prometasin
Prometazin
Prometazina
Prometazina [INN-Spanish]
Prometazine
Prometh
Promethacon
Promethaine
Promethazin
Promethazine
Promethazine (JAN/INN)
Promethazine [INN:BAN]
PromethazineHcl
Promethazinum
Promethazinum [INN-Latin]
Promethegan
Promethiazine
Promezathine
Prorex
Protazine
Prothazin
Prothazine
Provigan
Pyrethia
Pyrethiazine
RP 3277
Remsed
Romergan
Rumergan
SKF 1498
SPBio_000799
SPBio_002895
Spectrum2_000840
Spectrum3_001019
Spectrum4_001149
Spectrum5_000977
Spectrum_000868
Tanidil
Thiergan
UNII-FF28EJQ494
Valergine
Vallergine
WLN: T C666 BN ISJ B1Y1&N1&1
WY 509
Zipan-25
promethazine
31
Medroxyprogesterone acetateapproved, investigationalPhase 314571-58-9
Synonyms:
(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione
17-Acetoxy-6alpha-methylprogesterone
17-Acetoxy-6α-methylprogesterone
17alpha-Hydroxy-6alpha-methylprogesterone acetate
17α-hydroxy-6α-methylprogesterone acetate
6-alpha-Methyl-17-alpha-acetoxyprogesterone
6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate
6alpha-Methyl-17-acetoxy progesterone
 
6alpha-Methyl-17alpha-hydroxyprogesterone acetate
6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate
6α-Methyl-17-acetoxy progesterone
6α-Methyl-17α-hydroxyprogesterone acetate
MPA
Medroxyacetate progesterone
Medroxyprogesterone 17-acetate
Medroxyprogesterone acetate
Methylacetoxyprogesterone
Metigestrona
32
Sorafenibapproved, investigationalPhase 3, Phase 2692284461-73-0216239, 406563
Synonyms:
284461-73-0
4(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide
4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide
4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic acid methyamide-4-methylbenzenesulfonate
4-(4-{3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide
4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
AB1004622
AC-1674
AC1L50CF
BAX
BAY 43-9006
BAY 43-9006 (free base)
BAY 43-9006 tosylate salt
BAY 439006
BAY 54-9085 (tosylate salt)
BAY-43-0006
BAY-43-9006
BAY-54-9085
BAY43-9006
BRD-K23984367-001-01-8
Bio-0100
CHEBI:47228
CHEBI:50924
CHEMBL1336
CID216239
 
D08524
DB00398
DB07438
EN002709
I06-0856
K00597a
Kinome_766
LS-186067
LS-187021
LS-187788
MolPort-003-850-270
N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea
N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea
N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcar bamoyl)-4-pyridyloxy)phenyl)urea
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea
NCGC00167488-01
NSC-724772
NSC747971
Nexavar
STK627350
Sorafenib
Sorafenib (INN)
Sorafenib [INN]
Sorafenib tosylate
Sorafenibum
UNII-9ZOQ3TZI87
ZINC01493878
nchembio.117-comp17
sorafenib
sorafenibum
33
Sunitinibapproved, investigationalPhase 3, Phase 1, Phase 2500341031-54-7, 557795-19-45329102
Synonyms:
(2S)-2-hydroxybutanedioic acid
1H-Pyrrole-3-carboxamide, N-(2-(diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-, (2S)-hydroxybutanedioate (1:1)
1H-Pyrrole-3-carboxamide, N-(2-(diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-, (2S)-hydroxybutanedioate (1:1)
326914-13-0
341031-54-7
5-(5-FLUORO-2-OXO-1,2-DIHYDRO-INDOL-3-YLIDENEMETHYL)-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID (2-DIETHYLAMINO-ETHYL)-AMIDE
557795-19-4
AC1NS62J
AC1O5CMQ
AKOS005145765
Butanedioic acid, hydroxy-, (2S)-, compd. with N-(2-(diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (1:1)
CHEBI:38940
CHEBI:550864
CHEMBL1567
CHEMBL535
CID5329102
CID6456015
D06402
D08552
DB01268
DB07417
EN002687
FT-0083555
FT-0083556
I01-1229
K00588a
KS-5022
LS-186078
LS-187023
LS-187648
MolPort-003-986-763
N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-hydroxybutanedioate
N-(2-diethylaminoethyl)-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
NCGC00164631-01
 
NSC736511
NSC750690
PDGF TK antagonist
PHA-290940AD
PNU-290940AD
S1042_Selleck
ST51053712
SU 011248
SU 11248
SU-010398
SU-011248 L-malate salt
SU-11248
SU-11248 L-malate salt
SU-11248J
SU-12662
SU010398
SU011248
SU011248 L-malate salt
SU11248
Su-011248
Sunitanib
Sunitinib
Sunitinib (INN)
Sunitinib (free base)
Sunitinib malate
Sunitinib malate (JAN/USAN)
Sunitinib malate [USAN]
Sunitinibum
Sutent
Sutent (TN)
Sutent, SU-11248
TL8002546
UNII-LVX8N1UT73
UNII-V99T50803M
sunitinib
sunitinibum
34
MethotrexateapprovedPhase 3, Phase 1, Phase 215181959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
35
Miconazoleapproved, investigational, vet_approvedPhase 3, Phase 2, Phase 1362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
36
Lidocaineapproved, vet_approvedPhase 31226137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
37
Acetylcarnitineapproved, investigationalPhase 3443040-38-81
Synonyms:
(+-)-Acetylcarnitine
(-)-Acetylcarnitine
(R)-Acetylcarnitine
ALCAR
Acetyl-L-(-)-carnitine
Acetyl-L-carnitine
Acetyl-carnitine
Acetylcarnitine
 
L-Acetylcarnitine
L-Carnitine acetyl ester
L-O-Acetylcarnitine
Levocarnitine acetyl
Nicetile
O-Acetyl-L-carnitine
O-Acetylcarnitine
O-acetyl-L-carnitine
acetyl-L-carnitine
38
LenograstimapprovedPhase 3, Phase 21202135968-09-1
Synonyms:
G-CSF (CHO cell derived)
Glycosylated recombinant G-CSF
Glycosylated recombinant granulocyte colony stimulating factor
 
Granulocyte colony stimulating factor 3 (CHO cell derived)
Granulocyte colony-stimulating factor lenograstim
Lenograstim (genetical recombination)
Lenograstim rDNA
39
LevoleucovorinapprovedPhase 3, Phase 2, Phase 171168538-85-2
Synonyms:
(6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid
(6S)-5-formyltetrahydrofolic acid
(6S)-Folinic acid
(6S)-Leucovorin
 
(S)-Leucovorin
Citrovorum factor
L-Folinic acid
Levofolene
Levofolinic acid
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
40
GoserelinapprovedPhase 322965807-02-547725, 5311128
Synonyms:
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
AC1NSK1T
CID5311128
Goserelin
Goserelin acetate
 
HMS2089D16
HS-2015
ICI-118630
MolPort-006-823-831
ZD-9393
Zoladex
goserelin
41
leucovorinapprovedPhase 3, Phase 2, Phase 1108958-05-9143, 54575
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
42
EverolimusapprovedPhase 3, Phase 2, Phase 11896159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
Zortress
everolimus
43
Irinotecanapproved, investigationalPhase 3, Phase 2, Phase 1108097682-44-5, 100286-90-660838
Synonyms:
(+)-Irinotecan
(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE
(4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-4,12-dihydro-1H-pyrano[3,4-f]quinolino[2,3-a]indolizin-9-yl 4-piperidylpiperidinecarboxylate
1u65
97682-44-5
AC-7469
AC1L1U0Z
AC1Q6PGI
BRD-K08547377-003-02-4
BSPBio_002346
Bio-0054
Biotecan
Biotecan (TN)
C16641
C33H38N4O6
CHEBI:105985
CHEMBL481
CID60838
CP0
Campothecin-11
Campto
Camptosar
 
Camptosar, Campto, CPT-11, Irinotecan
Camptothecin-11
D08086
DB00762
FT-0083650
HSDB 7607
IRINOTECAN HYDROCHLORIDE Trihydrate
IRINOTECAN, CPT-11
Irinotecan (INN)
Irinotecan Hcl
Irinotecan Hydrochloride
Irinotecan Hydrochloride Trihydrate
Irinotecan [INN:BAN]
Irinotecan hydrochloride
Irinotecanum
Irinotecanum [INN-Latin]
LS-44589
NCI60_005051
NSC728073
S1198_Selleck
TL8006026
UNII-7673326042
irinotecan
44
Oxaliplatinapproved, investigationalPhase 3, Phase 2, Phase 1141261825-94-35310940, 9887054, 43805, 6857599, 9887054
Synonyms:
CHEMBL1201055
CID9887054
D01790
DACPLAT
Diaminocyclohexane Oxalatoplatinum
Eloxatin
Eloxatin (TN)
Elplat
Foloxatine
L-OHP
Oxalatoplatin
 
Oxalatoplatinum
Oxaliplatin (JAN/USAN/INN)
Oxaliplatin [Usan:Inn:Ban]
Oxaliplatino [Spanish]
Oxaliplatinum [Latin]
Oxaloplatine [French]
Oxaloplatino [Spanish]
Transplatin
oxaliplatin
oxaliplatine
oxaliplatino
oxaliplatinum
45
MetforminapprovedPhase 2, Phase 31746657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
46
Vinorelbineapproved, investigationalPhase 3, Phase 237171486-22-160780, 44424639
Synonyms:
5'-Noranhydrovinblastine
71486-22-1
AC1L1KVK
AC1L1TWQ
AC1L75Q4
ANX-530
Ambap71486-22-1
BIDD:PXR0186
C45H54N4O8
CHEBI:480999
CHEMBL607994
CID355119
CID5311497
CID5672
CID60780
CID6426842
D08680
DB00361
Eunades
Exelbine
HMS2090E13
HSDB 7665
I06-0084
I06-0085
KW 2307
KW 2307 base
KW-2307
 
LS-97533
MolPort-006-822-661
MolPort-006-823-869
NCGC00165966-02
NVB
Navelbine
Navelbine (TN)
Navelbine Base
Navelbine base
Nor-5'-anhydrovinblastine
SDP-012
UNII-Q6C979R91Y
Vinorelbin
Vinorelbina
Vinorelbina [Spanish]
Vinorelbine
Vinorelbine (INN)
Vinorelbine Bitartrate
Vinorelbine Ditartarate
Vinorelbine Ditartrate
Vinorelbine Tartrate
Vinorelbine [INN:BAN]
Vinorelbine ditartrate
Vinorelbine tartrate
Vinorelbinum
Vinorelbinum [Latin]
methyl (2b,3b,4b,5a,12b,19a)-4-(acetyloxy)-15-[(6R,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate
methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-acetoxy-15-[(6R,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate
vinorelbine
47
Bevacizumabapproved, investigationalPhase 3, Phase 21968216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
48
PilocarpineapprovedPhase 32754-71-7, 92-13-75910
Synonyms:
(+)-Pilocarpine
(3S,4R)-3-Ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone
(3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one
(3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one
(3S,4R)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone
(3S-cis)-3-Ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone
(3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone
(3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone
3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)dihydrofuran-2-one
3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydro-2(3H)-furanone
3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one
3-ethyl-4-((1-methyl-1H-imidazol-5-yl)methyl)dihydro-2(3H)-furanone
3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one
54-71-7
91484-73-0
92-13-7
AC1L1J0W
AC1L1LEF
AC1Q6MOP
AI3-50523
AR-1F3128
Adsorbocarpine
Almocarpine
Amistura P
BIDD:GT0217
BPBio1_000548
BRD-K85090592-008-05-2
BSPBio_000498
BSPBio_002191
C07474
CHEBI:39460
CHEBI:8207
CHEMBL550
CID4819
CID5910
D00525
DB01085
DivK1c_000358
EINECS 202-128-4
Epicar
HMS2089K17
HSDB 3163
IDI1_000358
Imidazole-5-butyric acid, alpha-ethyl-beta-(hydroxymethyl)-1-methyl-, gamma-lactone
Isopto carpine
Isoptocarpine
KBio1_000358
KBio2_001587
KBio2_004155
KBio2_006723
KBio3_001691
KBioGR_000956
KBioSS_001587
L001181
LS-187208
LS-7661
Lopac0_000950
Lopac0_000960
Mi-Pilo
Minims Pilocarpine
Miocarpine
MolPort-002-512-506
NCGC00023339-03
 
NCGC00023339-06
NCGC00023339-07
NCGC00023339-08
NCGC00023339-09
NCGC00023339-12
NCGC00023339-13
NCI60_004403
NINDS_000358
NSC5746
Ocu-Carpine
Ocusert
Ocusert P 20
Ocusert Pilo-40
Ocusert pilo
Ocusert pilo-20
Ocusert pilo-20 (TN)
P.V. Carpine Liquifilm
Pilagan
Pilocarpin
Pilocarpine
Pilocarpine (JAN/USP)
Pilocarpine HCl
Pilocarpine Mononitrate, (3S-cis)-Isomer
Pilocarpine [USAN:BAN:JAN]
Pilocarpine chloride
Pilocarpine hydrochloride
Pilocarpine monohydrochloride
Pilocarpine muriate
Pilocarpine nitrate
Pilocarpine, Monohydrochloride, (3S-cis)-Isomer
Pilocarpol
Pilokarpin
Pilokarpin monohydrochloride
Pilokarpol
Piloptic-1
Piloptic-1/2
Piloptic-2
Piloptic-3
Piloptic-4
Piloptic-6
Pilostat
Prestwick0_000449
Prestwick1_000449
Prestwick2_000449
Prestwick3_000449
SDCCGMLS-0003164.P005
SPBio_001287
SPBio_002437
STOCK1N-18408
Salagen
Spectrum2_001284
Spectrum3_000546
Spectrum4_000478
Spectrum5_001379
Spectrum_001107
Spersacarpine
Spersacarpine hydrochloride
Syncarpine
Tocris-0694
UNII-01MI4Q9DI3
ZINC00075008
beta-Pilocarpine hydrochloride
isopilocarpine
nchembio.78-comp9
pilocarpine
49
Topotecanapproved, investigationalPhase 2, Phase 3339119413-54-6, 123948-87-860700
Synonyms:
(4S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
(S)-10-((Dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE
(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dione
(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
123948-87-8
9-Dimethylaminomethyl-10-hydroxycamptothecin
9-[(dimethylamino)Methyl]-10-hydroxy-(4S)-camptothecin
AC-11592
AC1L1TQZ
AC1Q6APZ
BSPBio_002348
C11158
C23H23N3O5
CCRIS 8163
CHEBI:107501
CHEBI:46035
CHEMBL84
CID60700
D08618
DB01030
HMS2090B20
HSCI1_000228
Hycamptamine
Hycamptin
Hycamtamine
Hycamtin
Hycamtin (TN)
LS-127395
 
MLS000759456
NCGC00178695-01
NCI60_004771
NCIStruc1_001659
NCIStruc2_001796
NChemBio.2007.10-comp24
NSC609699
SK&F-104864-A
SKF 104864
SKF-104864-A
SKF-S 104864
SMP2_000312
SMP2_000327
SMR000466344
TOPO
TOPOTECAN, HYCAMTIN
TPT
TTC
Topotecan (BAN)
Topotecan Hcl
Topotecan Hydrochloride
Topotecan Lactone
Topotecan Monohydrochloride, (S)-Isomer
Topotecan [INN:BAN]
Topotecan lactone
Topotecane
Topotecane [INN-French]
Topotecanum
Topotecanum [INN-Latin]
UNII-7M7YKX2N15
topotecan
50
Letrozoleapproved, investigationalPhase 3, Phase 2, Phase 1382112809-51-53902
Synonyms:
1-[Bis-(4-cyanophenyl)methyl]-1,2,4-triazole
1-[bis(4-cyanophenyl)methyl]-1,2,4-triazole
112809-51-5
4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile
4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile
4,4'-(1H-1,2,4-triazol-1-yl-methylene)-bis(benzonitrile)
4,4'-(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile
4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile Letrozole
4,4'-(1h-1,2,4-triazol-1-ylmethylene) bis-benzonitrile
4,4'-(1h-1,2,4-triazol-1-ylmethylene)bis-benzonitrile
4,4'-(1h-1,2,4-triazol-1-ylmethylene)bisbenzonitrile
4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile
AB00514009
AC-1193
AC1L1GYT
AKOS005145822
BIDD:GT0015
BIDD:PXR0130
BPBio1_001331
BRD-K88789588-001-03-2
BSPBio_001209
Bio-0057
C067431
C08163
C17H11N5
CAS-112809-51-5
CCRIS 8822
CGS 20267
CGS 20267, Femara, Piroxicam, Letrozole
CGS-20267
CHEBI:6413
CHEMBL1444
CID3902
CPD000466343
D00964
 
DB01006
FEM-345
Femara
Femara (TN)
Femera
HMS1571M11
HMS2051E08
HMS2089L22
HSDB 7461
I06-0022
LS-38788
Letoval
Letrozol
Letrozole
Letrozole (JAN/USP/INN)
Letrozole [USAN:INN]
MLS000759455
MLS001424038
MLS002584991
MolPort-003-848-373
NCGC00016973-01
NCGC00016973-02
NSC719345
Novartis Brand of Letrozole
Prestwick0_001025
Prestwick1_001025
Prestwick2_001025
Prestwick3_001025
S1235_Selleck
SAM001246649
SMR000466343
SPBio_003070
TL8000371
UNII-7LKK855W8I
ZINC03778874
letrozole

Interventional clinical trials:

(show top 50)    (show all 530)
idNameStatusNCT IDPhase
1Randomized Trial of Follow-up Strategies in Breast CancerCompletedNCT00156039Phase 4
2Guilford Genomic Medicine Initiative (GGMI)CompletedNCT01372553Phase 4
3Trial of Patient Navigation-ActivationCompletedNCT00496678Phase 4
4Life Quality and Mental State in Patients With Breast CancerCompletedNCT01458457Phase 4
5Exercise and Phytoestrogens: Effect on Factors Predisposing to Cardiovascular Disease(CVD) in Postmenopausal WomenCompletedNCT01048606Phase 4
6Assessment and Tracking of Long-term Alefacept SafetyTerminatedNCT00454701Phase 4
7S0226 Anastrozole With or Without Fulvestrant as First-Line Therapy in Postmenopausal Women With Metastatic Breast CancerUnknown statusNCT00075764Phase 3
8Resource-sparing Post-mastectomy Radiotherapy in Breast CancerUnknown statusNCT01452672Phase 3
9Paclitaxel and Carboplatin or Ifosfamide in Treating Patients With Newly Diagnosed Persistent or Recurrent Uterine, Ovarian, Fallopian Tube, or Peritoneal Cavity CancerUnknown statusNCT00954174Phase 3
10RCT of a Group Intervention for Women With a Family History of Breast CancerCompletedNCT00150917Phase 3
11Fatigue Intervention Trial for Breast Cancer SurvivorsCompletedNCT00513136Phase 3
12Healing Touch and Health-Related Quality of Life in Women With Breast Cancer Receiving Radiation TherapyCompletedNCT00612443Phase 2, Phase 3
13Enhancing Connections: Helping the Mother With Breast Cancer Support Her ChildCompletedNCT00194571Phase 3
14Study of Tamoxifen and Raloxifene (STAR) for the Prevention of Breast Cancer in Postmenopausal WomenCompletedNCT00003906Phase 3
15Comparison of Two Combination Chemotherapy Regimens in Treating Women With Breast CancerCompletedNCT00087178Phase 3
16Randomized Trial Of Exemestane Versus Continued Tamoxifen In Postmenopausal Women With Early Breast CancerCompletedNCT00038467Phase 3
17Anastrozole or Tamoxifen in Treating Postmenopausal Women With Ductal Carcinoma in Situ Who Are Undergoing Lumpectomy and Radiation TherapyCompletedNCT00053898Phase 3
18Comparison of Combination Chemotherapy Regimens in Treating Older Women Who Have Undergone Surgery for Breast CancerCompletedNCT00024102Phase 3
19Combination Chemotherapy in Treating Women With Breast CancerCompletedNCT00003519Phase 3
20Nutrition Intervention in Treating Women With Breast CancerCompletedNCT00002564Phase 3
21Exemestane in Treating Postmenopausal Women With Resected Stage I, Stage II, or Stage IIIA Breast Cancer Who Have Completed 5 Years of TamoxifenCompletedNCT00016432Phase 3
22Combination Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA (cT1-3, N0-1, M0) Breast Cancer and Positive Axillary Lymph NodesCompletedNCT00003782Phase 3
23Chemotherapy in Treating Women With Breast Cancer That Can Be Surgically RemovedCompletedNCT00002707Phase 3
24Continued Efficacy and Safety of Zoledronic Acid (q 4 Wks vs. q 12 Wks) in the 2nd Year of Treatment in Patients With Bone Metastases From Breast CancerCompletedNCT00320710Phase 3
25Hormone Therapy in Treating Postmenopausal Women With Receptor-Positive Breast CancerCompletedNCT00002646Phase 3
26S9630, Medroxyprogesterone in Treating Women With Breast CancerCompletedNCT00002920Phase 3
27The BEACON Study (Breast Cancer Outcomes With NKTR-102)CompletedNCT01492101Phase 3
28Pilocarpine in Treating Vaginal Dryness in Patients With Breast CancerCompletedNCT00343382Phase 3
29Flaxseed in Treating Postmenopausal Women With Hot Flashes Who Have a History of Breast Cancer or Other Cancer or Who Do Not Wish to Take Estrogen TherapyCompletedNCT00956813Phase 3
30S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, Stage II, or Stage IIIA Breast Cancer Undergoing ChemotherapyCompletedNCT00775645Phase 3
31Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon CancerCompletedNCT00079274Phase 3
32Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube CancerCompletedNCT00262847Phase 3
33Sunitinib Malate or Sorafenib Tosylate in Treating Patients With Kidney Cancer That Was Removed By SurgeryCompletedNCT00326898Phase 3
34Sunitinib Malate as Maintenance Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Treated With Combination ChemotherapyCompletedNCT00693992Phase 3
35S0421, Docetaxel and Prednisone With or Without Atrasentan in Treating Patients With Stage IV Prostate Cancer and Bone Metastases That Did Not Respond to Previous Hormone TherapyCompletedNCT00134056Phase 3
36Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With CancerCompletedNCT00489411Phase 3
37Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without ChemotherapyCompletedNCT02229539Phase 3
38Continues Cicatricial Perfusion of Ropivacaine Versus Placebo After Mastectomy : Rehabilitation After TreatmentRecruitingNCT02525211Phase 3
39Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast CancerRecruitingNCT01242800Phase 3
40Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With ChemotherapyRecruitingNCT01901094Phase 3
41S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast CancerRecruitingNCT01674140Phase 3
42Breast Cancer WEight Loss Study (BWEL Study)RecruitingNCT02750826Phase 3
43Reproductive Health Survivorship Care PlanRecruitingNCT02667626Phase 3
44Aspirin in Preventing Recurrence of Cancer in Patients With Node Positive HER2 Negative Stage II-III Breast Cancer After Chemotherapy, Surgery, and/or Radiation TherapyRecruitingNCT02927249Phase 3
45Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or MetastaticRecruitingNCT02115282Phase 3
46Platinum Based Chemotherapy or Capecitabine in Treating Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant ChemotherapyRecruitingNCT02445391Phase 3
47Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast CancerRecruitingNCT02488967Phase 3
48Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast CancerRecruitingNCT01272037Phase 3
49Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing SurgeryRecruitingNCT01953588Phase 3
50Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age ChildrenRecruitingNCT00685256Phase 3

Search NIH Clinical Center for Familial Breast Cancer

Genetic Tests for Familial Breast Cancer

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Anatomical Context for Familial Breast Cancer

About this section

MalaCards organs/tissues related to Familial Breast Cancer:

36
Breast, Lung, Testes, Bone, Prostate, Colon, Lymph node

Publications for Familial Breast Cancer

About this section

Articles related to Familial Breast Cancer:

(show top 50)    (show all 437)
idTitleAuthorsYear
1
Unique Features of Germline Variation in Five Egyptian Familial Breast Cancer Families Revealed by Exome Sequencing. (28076423)
2017
2
Survival in familial and non-familial breast cancer by age and stage at diagnosis. (26630529)
2016
3
Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer. (26824983)
2016
4
Tumor characteristics and prognosis in familial breast cancer. (27899083)
2016
5
Haplotype Analysis of BRCA1 Gene D17S855 and D17S1322 Markers in Iranian Familial Breast Cancer Patients. (27510018)
2016
6
Single nucleotide polymorphisms in the mitochondrial displacement loop and age-at-onset of familial breast cancer. (27158866)
2016
7
Detection of Human Papillomavirus Genotypes and Major BRCA Mutations in Familial Breast Cancer. (27186947)
2016
8
Screening of BRCA1/2 Mutations Using Direct Sequencing in Indonesian Familial Breast Cancer Cases. (27221885)
2016
9
Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care. (26786923)
2016
10
RAD51B in Familial Breast Cancer. (27149063)
2016
11
Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility. (26969729)
2016
12
Association Between Loss-of-Function Mutations Within the FANCM Gene and Early-Onset Familial Breast Cancer. (28033443)
2016
13
CpG methylation of APC promoter 1A in sporadic and familial breast cancer patients. (27983523)
2016
14
Phenotypic analysis of familial breast cancer: Comparison of BRCAx tumors with BRCA1-, BRCA2-carriers and non-familial breast cancer. (25736863)
2015
15
Reevaluation of the BRCA2 truncating allele c.9976Aa88>a88T (p.Lys3326Ter) in a familial breast cancer context. (26455428)
2015
16
Gene-expression patterns in peripheral blood classify familial breast cancer susceptibility. (26538066)
2015
17
Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls. (26283626)
2015
18
Analysis of PTEN in two BRCA1 and BRCA2 wild-type familial breast cancer patients. (26600843)
2015
19
FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor. (26130695)
2015
20
Immunoprofile from tissue microarrays to stratify familial breast cancer patients. (26312763)
2015
21
Tumour characteristics and survival in familial breast cancer prospectively diagnosed by annual mammography. (26037256)
2015
22
Two PALB2 germline mutations found in both BRCA1+ and BRCAx familial breast cancer. (25833210)
2015
23
Characterization of familial breast cancer in Saudi Arabia. (25923920)
2015
24
Double Heterozygosity of BRCA2 and STK11 in Familial Breast Cancer Detected by Exome Sequencing. (26576347)
2015
25
Triple-modality screening trial for familial breast cancer underlines the importance of magnetic resonance imaging and questions the role of mammography and ultrasound regardless of patient mutation status, age, and breast density. (25713430)
2015
26
Does familial breast cancer and thymoma suggest a cancer syndrome? A family perspective. (26344711)
2015
27
Epigenetic changes in BRCA1-mutated familial breast cancer. (25800897)
2015
28
Sister chromatid exchange: A possible approach to characterize familial breast cancer patients. (25434423)
2015
29
Impact of chemotherapy on telomere length in sporadic and familial breast cancer patients. (25528024)
2015
30
Considerations for comprehensive assessment of genetic predisposition in familial breast cancer. (25472498)
2015
31
Familial breast cancer - targeted therapy in secondary and tertiary prevention. (25960722)
2015
32
Gene analysis techniques and susceptibility gene discovery inA non-BRCA1/BRCA2 familial breast cancer. (25936246)
2015
33
The importance of analysis of long-range rearrangement of BRCA1 and BRCA2 in genetic diagnosis of familial breast cancer. (26271414)
2015
34
Effect of BRCA2 mutation on familial breast cancer survival: A systematic review and meta-analysis. (26489613)
2015
35
Whole-genome Linkage Analysis and Sequence Analysis of Candidate Loci in Familial Breast Cancer. (26026075)
2015
36
A risk management model for familial breast cancer: A new application using Fuzzy Cognitive Map method. (26220142)
2015
37
Genetic anticipation of familial breast cancer with or without BRCA mutation in the Korean population. (24853100)
2014
38
Mitochondrial DNA variants and risk of familial breast cancer: an exploratory study. (24603941)
2014
39
Talking about familial breast cancer risk: topics and strategies to enhance mother-daughter interactions. (24633365)
2014
40
Association of BRCA1 K1183R polymorphism with survival in BRCA1/2-negative chinese familial breast cancer. (24600974)
2014
41
A multi-institutional study on the association between BRCA1/BRCA2 mutational status and triple-negative breast cancer in familial breast cancer patients. (24894343)
2014
42
Relation between HPV genotypes and BRCA mutation in familial breast cancer. (25293631)
2014
43
Altered Significance of D'Amico Risk Classification in Prostate Cancer Patients linked to a Familial Breast Cancer (kConFab) cohort. (24784491)
2014
44
Analysis of BRCA1and BRCA2 large genomic rearrangements in Sri Lankan familial breast cancer patients and at risk individuals. (24906410)
2014
45
Novel nonsense mutation of BRCA2 gene in a Moroccan man with familial breast cancer. (25320599)
2014
46
Large genomic rearrangement of BRCA1 and BRCA2 genes in familial breast cancer patients in Korea. (24566764)
2014
47
Evaluation of Genetic Variations in miRNA-Binding Sites of BRCA1 and BRCA2 Genes as Risk Factors for the Development of Early-Onset and/or Familial Breast Cancer. (25339023)
2014
48
MicroRNA expression profiling in male and female familial breast cancer. (25393370)
2014
49
Identification of sequence polymorphisms in the mitochondrial displacement loop as risk factors for sporadic and familial breast cancer. (24430364)
2014
50
Wild-type genotypes of BRCA1 gene SNPs combined with micro-RNA over-expression in mammary tissue leading to familial breast cancer with an increased risk of distant metastases' occurrence. (25273865)
2014

Variations for Familial Breast Cancer

About this section

Clinvar genetic disease variations for Familial Breast Cancer:

5 (show all 1,884)
id Gene Variation Type Significance SNP ID Assembly Location
1PALB2NM_024675.3(PALB2): c.3549C> G (p.Tyr1183Ter)SNVLikely pathogenic, Pathogenic, risk factorrs118203998GRCh37Chr 16, 23614792: 23614792
2BRCA1NM_007294.3(BRCA1): c.2995_2996delCTinsTA (p.Leu999Ter)indelPathogenicrs273899692GRCh38Chr 17, 43092535: 43092536
3BRCA2NM_000059.3(BRCA2): c.891_899delAACAGTTGTinsGATACTTCAG (p.Thr298Ilefs)indelPathogenicrs276174914GRCh38Chr 13, 32332369: 32332377
4BRCA2NM_000059.3(BRCA2): c.1190_1191insTTAG (p.Gln397Hisfs)insertionPathogenicrs80359266GRCh37Chr 13, 32906805: 32906806
5BRCA2NM_000059.3(BRCA2): c.5222_5225delGTAA (p.Ser1741Thrfs)deletionPathogenicrs80359498GRCh38Chr 13, 32339577: 32339580
6PALB2NM_024675.3(PALB2): c.-200-?_3113+?deldeletionPathogenicChr na, -1: -1
7PALB2NM_024675.3(PALB2): c.1027C> T (p.Gln343Ter)SNVPathogenic, risk factorrs180177097GRCh38Chr 16, 23635519: 23635519
8PALB2NM_024675.3(PALB2): c.1050_1051delAAinsTCT (p.Gln350Hisfs)indelPathogenicrs180177098GRCh38Chr 16, 23635495: 23635496
9PALB2NM_024675.3(PALB2): c.1056_1057delGA (p.Lys353Ilefs)deletionPathogenicrs180177099GRCh38Chr 16, 23635489: 23635490
10PALB2NM_024675.3(PALB2): c.1314delA (p.Phe440Leufs)deletionPathogenicrs515726065GRCh38Chr 16, 23635232: 23635232
11PALB2NM_024675.3(PALB2): c.1317delG (p.Phe440Leufs)deletionPathogenicrs515726067GRCh38Chr 16, 23635229: 23635229
12PALB2NM_024675.3(PALB2): c.1479delC (p.Thr494Leufs)deletionPathogenicrs515726071GRCh38Chr 16, 23635067: 23635067
13PALB2NM_024675.3(PALB2): c.1592delT (p.Leu531Cysfs)deletionPathogenic, risk factorrs180177102GRCh38Chr 16, 23634954: 23634954
14PALB2NM_024675.3(PALB2): c.1633G> T (p.Glu545Ter)SNVPathogenicrs180177103GRCh38Chr 16, 23634913: 23634913
15PALB2NM_024675.3(PALB2): c.172_175delTTGT (p.Gln60Argfs)deletionLikely pathogenic, Pathogenic, risk factorrs180177143GRCh38Chr 16, 23637886: 23637889
16PALB2NM_024675.3(PALB2): c.1947dupA (p.Glu650Argfs)duplicationLikely pathogenic, Pathogenicrs515726075GRCh38Chr 16, 23630207: 23630207
17PALB2NM_024675.3(PALB2): c.196C> T (p.Gln66Ter)SNVLikely pathogenic, Pathogenicrs180177083GRCh38Chr 16, 23637865: 23637865
18PALB2NM_024675.3(PALB2): c.2145_2146delTA (p.Asp715Glufs)deletionPathogenicrs515726081GRCh38Chr 16, 23630008: 23630009
19PALB2NM_024675.3(PALB2): c.229delT (p.Cys77Valfs)deletionPathogenicrs180177084GRCh38Chr 16, 23636317: 23636317
20PALB2NM_024675.3(PALB2): c.2323C> T (p.Gln775Ter)SNVPathogenic, risk factorrs180177111GRCh38Chr 16, 23629831: 23629831
21PALB2NM_024675.3(PALB2): c.2386G> T (p.Gly796Ter)SNVLikely pathogenic, Pathogenicrs180177112GRCh38Chr 16, 23629768: 23629768
22PALB2PALB2: c.2515-1G> TSNVLikely pathogenic, Pathogenic, risk factorrs587776417GRCh38Chr 16, 23629276: 23629276
23PALB2NM_024675.3(PALB2): c.2587-?_3201+?del (p.Asn863_Met1067del)deletionPathogenicChr na, -1: -1
24PALB2NM_024675.3(PALB2): c.2686dupT (p.Ser896Phefs)duplicationPathogenicrs515726091GRCh38Chr 16, 23626298: 23626298
25PALB2NM_024675.3(PALB2): c.2718G> A (p.Trp906Ter)SNVLikely pathogenic, Pathogenicrs180177122GRCh38Chr 16, 23626266: 23626266
26PALB2NM_024675.3(PALB2): c.2761C> T (p.Gln921Ter)SNVPathogenicrs180177124GRCh38Chr 16, 23624082: 23624082
27PALB2NM_024675.3(PALB2): c.2920_2921delAA (p.Lys974Glufs)deletionPathogenicrs180177126GRCh38Chr 16, 23623044: 23623045
28PALB2NM_024675.3(PALB2): c.2982dupT (p.Ala995Cysfs)duplicationLikely pathogenic, Pathogenicrs180177127GRCh38Chr 16, 23622983: 23622983
29PALB2NM_024675.3(PALB2): c.3026delC (p.Pro1009Leufs)deletionPathogenicrs180177131GRCh38Chr 16, 23621449: 23621449
30PALB2NM_024675.3(PALB2): c.3048delT (p.Phe1016Leufs)deletionPathogenicrs515726104GRCh38Chr 16, 23621427: 23621427
31PALB2NM_024675.3(PALB2): c.3113G> A (p.Trp1038Ter)SNVLikely pathogenic, Pathogenic, risk factorrs180177132GRCh38Chr 16, 23621362: 23621362
32PALB2NM_024675.3(PALB2): c.3116delA (p.Asn1039Ilefs)deletionLikely pathogenic, Pathogenic, risk factorrs180177133GRCh38Chr 16, 23614089: 23614089
33PALB2PALB2: c.3202-?_*297del (p.Gly1068_Ser1186delins45)deletionPathogenicGRCh38Chr 16, 23603162: 23608012
34PALB2NM_024675.3(PALB2): c.3256C> T (p.Arg1086Ter)SNVLikely pathogenic, Pathogenic, risk factorrs587776527GRCh38Chr 16, 23607958: 23607958
35PALB2NM_024675.3(PALB2): c.3323delA (p.Tyr1108Serfs)deletionPathogenicrs180177135GRCh38Chr 16, 23607891: 23607891
36PALB2NM_024675.3(PALB2): c.3350+4A> GSNVPathogenicrs180177136GRCh38Chr 16, 23607860: 23607860
37PALB2NM_024675.3(PALB2): c.3362delG (p.Gly1121Valfs)deletionLikely pathogenic, Pathogenicrs515726117GRCh38Chr 16, 23603658: 23603658
38PALB2NM_024675.3(PALB2): c.3497delG (p.Gly1166Valfs)deletionPathogenicrs180177138GRCh38Chr 16, 23603523: 23603523
39PALB2NM_024675.3(PALB2): c.503C> A (p.Ser168Ter)SNVPathogenicrs515726122GRCh38Chr 16, 23636043: 23636043
40PALB2NM_024675.3(PALB2): c.509_510delGA (p.Arg170Ilefs)deletionPathogenicrs515726123GRCh38Chr 16, 23636036: 23636037
41PALB2NM_024675.3(PALB2): c.697delG (p.Val233Leufs)deletionPathogenicrs180177090GRCh38Chr 16, 23635849: 23635849
42PALB2NM_024675.3(PALB2): c.72delG (p.Arg26Glyfs)deletionPathogenicrs180177142GRCh38Chr 16, 23638106: 23638106
43PALB2NM_024675.3(PALB2): c.751C> T (p.Gln251Ter)SNVPathogenicrs180177091GRCh38Chr 16, 23635795: 23635795
44PALB2NM_024675.3(PALB2): c.757_758delCT (p.Leu253Ilefs)deletionPathogenicrs180177092GRCh38Chr 16, 23635788: 23635789
45PALB2NM_024675.3(PALB2): c.758dupT (p.Ser254Ilefs)duplicationLikely pathogenic, Pathogenicrs515726126GRCh38Chr 16, 23635788: 23635788
46CHEK2NM_007194.3(CHEK2): c.444+1G> TSNVLikely pathogenic, Pathogenicrs121908698GRCh37Chr 22, 29121230: 29121230
47BARD1NM_000465.3(BARD1): c.1690C> T (p.Gln564Ter)SNVPathogenicrs587780021GRCh37Chr 2, 215610566: 215610566
48BARD1NM_000465.3(BARD1): c.1935_1954dup20 (p.Glu652Valfs)duplicationPathogenicrs587780024GRCh37Chr 2, 215595182: 215595201
49CHEK2NM_007194.3(CHEK2): c.1100delC (p.Thr367Metfs)deletionPathogenicrs555607708GRCh37Chr 22, 29091857: 29091857
50CHEK2NM_007194.3(CHEK2): c.1263delT (p.Ser422Valfs)deletionPathogenicrs587780174GRCh37Chr 22, 29091227: 29091227
51CHEK2NM_007194.3(CHEK2): c.444+1G> ASNVPathogenicrs121908698GRCh37Chr 22, 29121230: 29121230
52PALB2NM_024675.3(PALB2): c.1240C> T (p.Arg414Ter)SNVPathogenicrs180177100GRCh38Chr 16, 23635306: 23635306
53PALB2NM_024675.3(PALB2): c.3456dupA (p.Pro1153Thrfs)duplicationLikely pathogenic, Pathogenicrs587776426GRCh38Chr 16, 23603564: 23603564
54PALB2NM_024675.3(PALB2): c.3549C> A (p.Tyr1183Ter)SNVPathogenicrs118203998GRCh38Chr 16, 23603471: 23603471
55RAD51NM_002875.4(RAD51): c.449G> A (p.Arg150Gln)SNVPathogenicrs121917739GRCh37Chr 15, 41011016: 41011016
56PALB2NM_024675.3(PALB2): c.2167_2168delAT (p.Met723Valfs)deletionPathogenicrs587776416GRCh38Chr 16, 23629986: 23629987
57BRIP1NM_032043.2(BRIP1): c.627+1G> ASNVLikely pathogenic, Pathogenicrs587780833GRCh37Chr 17, 59924461: 59924461
58BRCA1NM_007294.3(BRCA1): c.5205delA (p.Val1736Serfs)deletionPathogenicrs587781258GRCh37Chr 17, 41209141: 41209141
59CHEK2NM_007194.3(CHEK2): c.283C> T (p.Arg95Ter)SNVPathogenicrs587781269GRCh38Chr 22, 28734439: 28734439
60BRIP1NM_032043.2(BRIP1): c.133G> T (p.Glu45Ter)SNVPathogenicrs587781292GRCh38Chr 17, 61859868: 61859868
61BRIP1NM_032043.2(BRIP1): c.1871C> A (p.Ser624Ter)SNVPathogenicrs587781321GRCh38Chr 17, 61780325: 61780325
62PALB2NM_024675.3(PALB2): c.3507_3508delTC (p.His1170Phefs)deletionLikely pathogenic, Pathogenicrs587776428GRCh38Chr 16, 23603512: 23603513
63PALB2NM_024675.3(PALB2): c.1546delA (p.Arg516Glufs)deletionPathogenicrs587781560GRCh37Chr 16, 23646321: 23646321
64CHEK2NM_007194.3(CHEK2): c.151C> T (p.Gln51Ter)SNVPathogenicrs587781592GRCh37Chr 22, 29130559: 29130559
65BARD1NM_000465.3(BARD1): c.1652C> G (p.Ser551Ter)SNVPathogenicrs587781707GRCh37Chr 2, 215617196: 215617196
66PALB2NM_024675.3(PALB2): c.1037_1041delAAGAA (p.Lys346Thrfs)deletionPathogenicrs587776410GRCh37Chr 16, 23646826: 23646830
67BARD1NM_000465.3(BARD1): c.1921C> T (p.Arg641Ter)SNVPathogenicrs587781948GRCh37Chr 2, 215595215: 215595215
68CHEK2NM_007194.3(CHEK2): c.279G> A (p.Trp93Ter)SNVPathogenicrs587782070GRCh38Chr 22, 28734443: 28734443
69CHEK2NM_007194.3(CHEK2): c.591delA (p.Val198Phefs)deletionPathogenicrs587782245GRCh37Chr 22, 29120966: 29120966
70BRIP1NM_032043.2(BRIP1): c.2400C> G (p.Tyr800Ter)SNVPathogenicrs574552037GRCh37Chr 17, 59793404: 59793404
71PALB2NM_024675.3(PALB2): c.2931dupA (p.Val978Serfs)duplicationPathogenicrs587782570GRCh38Chr 16, 23623034: 23623034
72BARD1NM_000465.3(BARD1): c.1212C> G (p.Tyr404Ter)SNVPathogenicrs587782681GRCh38Chr 2, 214780662: 214780662
73CHEK2NM_007194.3(CHEK2): c.1567delC (p.Arg523Valfs)deletionPathogenicrs587782684GRCh38Chr 22, 28687962: 28687962
74CHEK2NM_007194.3(CHEK2): c.247delC (p.Gln83Lysfs)deletionPathogenicrs587782766GRCh38Chr 22, 28734475: 28734475
75PALB2NM_024675.3(PALB2): c.3201+1G> CSNVLikely pathogenic, Pathogenicrs587776423GRCh38Chr 16, 23614003: 23614003
76PALB2NM_024675.3(PALB2): c.3426dupA (p.Leu1143Thrfs)duplicationPathogenicrs587776425GRCh38Chr 16, 23603594: 23603594
77BRCA2NM_000059.3(BRCA2): c.8490G> A (p.Trp2830Ter)SNVPathogenicrs587776351GRCh37Chr 13, 32945095: 32945095
78BRCA2NM_000059.3(BRCA2): c.787dupA (p.Ser263Lysfs)duplicationPathogenicrs690016538GRCh38Chr 13, 32331024: 32331024
79BRCA2NM_000059.3(BRCA2): c.3280A> T (p.Lys1094Ter)SNVPathogenicrs690016539GRCh38Chr 13, 32337635: 32337635
80BRCA2NM_000059.3(BRCA2): c.3291dupT (p.Asn1098Terfs)duplicationPathogenicrs690016540GRCh38Chr 13, 32337646: 32337646
81BRCA2NM_000059.3(BRCA2): c.3641delT (p.Val1214Glyfs)deletionPathogenicrs690016542GRCh38Chr 13, 32337996: 32337996
82BRCA1NM_007294.3(BRCA1): c.181T> G (p.Cys61Gly)SNVPathogenicrs28897672GRCh37Chr 17, 41258504: 41258504
83BRCA1NM_007294.3(BRCA1): c.68_69delAG (p.Glu23Valfs)deletionPathogenicrs386833395GRCh37Chr 17, 41276047: 41276048
84BRCA1NM_007294.3(BRCA1): c.2296_2297delAG (p.Ser766Terfs)deletionPathogenicrs80357780GRCh37Chr 17, 41245251: 41245252
85BRCA1NM_007294.3(BRCA1): c.3607C> T (p.Arg1203Ter)SNVPathogenicrs62625308GRCh37Chr 17, 41243941: 41243941
86BRCA1NM_007294.3(BRCA1): c.3756_3759delGTCT (p.Ser1253Argfs)deletionPathogenicrs80357868GRCh37Chr 17, 41243789: 41243792
87BRCA1NM_007294.3(BRCA1): c.4327C> T (p.Arg1443Ter)SNVPathogenicrs41293455GRCh37Chr 17, 41234451: 41234451
88BRCA1NM_007294.3(BRCA1): c.5266dupC (p.Gln1756Profs)duplicationPathogenicrs80357906GRCh37Chr 17, 41209082: 41209082
89BRCA1NM_007294.3(BRCA1): c.2389G> T (p.Glu797Ter)SNVPathogenicrs62625306GRCh37Chr 17, 41245159: 41245159
90BRCA1NM_007294.3(BRCA1): c.843_846delCTCA (p.Ser282Tyrfs)deletionPathogenicrs80357919GRCh37Chr 17, 41246702: 41246705
91BRCA1NM_007294.3(BRCA1): c.1556delA (p.Lys519Argfs)deletionPathogenicrs80357662GRCh37Chr 17, 41245992: 41245992
92BRCA1NM_007294.3(BRCA1): c.5324T> A (p.Met1775Lys)SNVPathogenicrs41293463GRCh37Chr 17, 41203088: 41203088
93BARD1NM_000465.3(BARD1): c.1996C> T (p.Gln666Ter)SNVLikely pathogenic, Pathogenicrs730881422GRCh38Chr 2, 214730416: 214730416
94BRCA1NM_007294.3(BRCA1): c.2938delA (p.Ile980Tyrfs)deletionPathogenicrs730881439GRCh38Chr 17, 43092593: 43092593
95BRCA1NM_007294.3(BRCA1): c.3767_3768delCA (p.Thr1256Argfs)deletionPathogenicrs730881440GRCh37Chr 17, 41243780: 41243781
96BRCA1NM_007294.3(BRCA1): c.5474_5481delGGCAGATG (p.Gly1825Valfs)deletionPathogenicrs730881441GRCh38Chr 17, 43045789: 43045796
97BRCA1NM_007294.3(BRCA1): c.45delT (p.Asn16Metfs)deletionPathogenicrs730881457GRCh38Chr 17, 43124052: 43124052
98BRCA1NM_007294.3(BRCA1): c.1340_1341delTT (p.Val447Alafs)deletionPathogenicrs730881458GRCh37Chr 17, 41246207: 41246208
99BRCA1NM_007294.3: c.1363insTinsertionPathogenicChr na, -1: -1
100BRCA1NM_007294.3(BRCA1): c.1860delT (p.His621Metfs)deletionPathogenicrs730881459GRCh38Chr 17, 43093671: 43093671
101BRCA1NM_007294.3: c.2726insAinsertionPathogenicChr na, -1: -1
102BRCA1NM_007294.3(BRCA1): c.2945delC (p.Pro982Hisfs)deletionPathogenicrs730881461GRCh38Chr 17, 43092586: 43092586
103BRCA1NM_007294.3: c.3108insTinsertionPathogenicChr na, -1: -1
104BRCA1NM_007294.3(BRCA1): c.3129_3138delTATTAATGAA (p.Asn1043Lysfs)deletionPathogenicrs730881462GRCh38Chr 17, 43092393: 43092402
105BRCA1NM_007294.3: c.3627insAinsertionPathogenicChr na, -1: -1
106BRCA1NM_007294.3: c.3648insAinsertionPathogenicChr na, -1: -1
107BRCA1NM_007294.3: c.3764insAinsertionPathogenicChr na, -1: -1
108BRCA1NM_007294.3: c.3908insTinsertionPathogenicChr na, -1: -1
109BRCA1NM_007294.3: c.4997insAinsertionPathogenicChr na, -1: -1
110BRCA1NM_007294.3(BRCA1): c.5332+2T> GSNVPathogenicrs80358182GRCh38Chr 17, 43051061: 43051061
111BRCA2NM_000059.3(BRCA2): c.670_673dupGATA (p.Thr225Argfs)duplicationPathogenicrs730881601GRCh37Chr 13, 32903618: 32903621
112BRCA2NM_000059.3(BRCA2): c.2380dupA (p.Met794Asnfs)duplicationPathogenicrs730881602GRCh38Chr 13, 32336735: 32336735
113BRCA2NM_000059.3(BRCA2): c.3010delA (p.Ser1004Valfs)deletionPathogenicrs730881604GRCh38Chr 13, 32337365: 32337365
114BRCA2NM_000059.3(BRCA2): c.4112dupA (p.Phe1372Valfs)duplicationPathogenicrs730881606GRCh38Chr 13, 32338467: 32338467
115BRCA2NM_000059.3(BRCA2): c.4168_4169delTT (p.Leu1390Glyfs)deletionPathogenicrs730881607GRCh38Chr 13, 32338523: 32338524
116BRCA2NM_000059.3(BRCA2): c.4277delC (p.Thr1426Asnfs)deletionPathogenicrs730881608GRCh38Chr 13, 32338632: 32338632
117BRCA2NM_000059.3(BRCA2): c.6267_6270dupGCAT (p.Ser2091Alafs)duplicationPathogenicrs730881611GRCh38Chr 13, 32340622: 32340625
118BRCA2NM_000059.3(BRCA2): c.7380_7381insG (p.Asn2461Glufs)insertionPathogenicrs730881612GRCh38Chr 13, 32355233: 32355234
119BRCA2NM_000059.3(BRCA2): c.7588delC (p.Gln2530Lysfs)deletionPathogenicrs730881613GRCh38Chr 13, 32356580: 32356580
120BRCA2NM_000059.3(BRCA2): c.7979_7991delATGATACGGAAAT (p.Tyr2660Leufs)deletionPathogenicrs730881614GRCh38Chr 13, 32363181: 32363193
121BRCA2NM_000059.3(BRCA2): c.8953+1delGdeletionPathogenicrs730881617GRCh38Chr 13, 32379516: 32379516
122BRCA2NM_000059.3(BRCA2): c.9728delC (p.Pro3243Leufs)deletionPathogenicrs730881618GRCh37Chr 13, 32972378: 32972378
123BRCA2NM_000059.3(BRCA2): c.9891_9894dupATTT (p.Gln3299Ilefs)duplicationPathogenicrs730881619GRCh38Chr 13, 32398404: 32398407
124BRCA2NM_000059.3(BRCA2): c.3820_3823delAAGA (p.Lys1274Terfs)deletionPathogenicrs730881620GRCh38Chr 13, 32338175: 32338178
125BRCA2NM_000059.3: c.3847_3848delTGdeletionPathogenicChr na, -1: -1
126BRIP1NM_032043.2(BRIP1): c.1204_1205insTGTG (p.Ala402Valfs)duplicationLikely pathogenic, Pathogenicrs730881647GRCh38Chr 17, 61799236: 61799239
127BRIP1NM_032043.2(BRIP1): c.2255_2256delAA (p.Lys752Argfs)deletionPathogenicrs730881649GRCh38Chr 17, 61744433: 61744434
128CHEK2NM_007194.3(CHEK2): c.405delA (p.Lys135Asnfs)deletionPathogenicrs730881699GRCh38Chr 22, 28725282: 28725282
129CHEK2NM_007194.3(CHEK2): c.409C> T (p.Arg137Ter)SNVLikely pathogenic, Pathogenicrs730881701GRCh38Chr 22, 28725278: 28725278
130PALB2NM_024675.3(PALB2): c.2727_2728delTT (p.Thr911Leufs)deletionLikely pathogenic, Pathogenicrs730881869GRCh38Chr 16, 23626256: 23626257
131PALB2NM_024675.3(PALB2): c.1059delA (p.Lys353Asnfs)deletionPathogenicrs730881872GRCh38Chr 16, 23635487: 23635487
132BARD1NM_000465.3(BARD1): c.334C> T (p.Arg112Ter)SNVPathogenicrs758972589GRCh37Chr 2, 215657051: 215657051
133CHEK2NM_007194.3(CHEK2): c.1489delG (p.Asp497Ilefs)deletionLikely pathogenic, Pathogenicrs774175654GRCh37Chr 22, 29085176: 29085176
134BRIP1NM_032043.2(BRIP1): c.890delA (p.Lys297Serfs)deletionPathogenicrs786202610GRCh37Chr 17, 59885856: 59885856
135BRIP1NM_032043.2(BRIP1): c.484C> T (p.Arg162Ter)SNVPathogenicrs747604569GRCh37Chr 17, 59926513: 59926513
136BRIP1NM_032043.2(BRIP1): c.2108delAinsTCC (p.Lys703Ilefs)indelPathogenicrs786203384GRCh37Chr 17, 59821942: 59821942
137CHEK2NM_007194.3(CHEK2): c.277delT (p.Trp93Glyfs)deletionPathogenicrs786203458GRCh37Chr 22, 29130433: 29130433
138BRIP1NM_032043.2(BRIP1): c.290_293delACAA (p.Asn97Metfs)deletionPathogenicrs763009188GRCh37Chr 17, 59934505: 59934508
139BRIP1NM_032043.2(BRIP1): c.2010dupT (p.Glu671Terfs)duplicationPathogenicrs775537066GRCh37Chr 17, 59853849: 59853849
140PALB2NM_024675.3(PALB2): c.2986G> T (p.Glu996Ter)SNVPathogenicrs786203775GRCh37Chr 16, 23634300: 23634300
141CHEK2NM_007194.3(CHEK2): c.85C> T (p.Gln29Ter)SNVPathogenicrs761494650GRCh37Chr 22, 29130625: 29130625
142PALB2NM_024675.3(PALB2): c.2920_2923delAAGA (p.Lys974Glyfs)deletionPathogenicrs786204122GRCh37Chr 16, 23634363: 23634366
143PALB2NM_024675.3(PALB2): c.1966_1967insAGAGGAAGCTGTATTTTTC (p.Pro656Glnfs)insertionPathogenicrs786204129GRCh38Chr 16, 23630187: 23630188
144PALB2NM_024675.3(PALB2): c.2597delG (p.Gly866Valfs)deletionPathogenicrs786204156GRCh37Chr 16, 23637708: 23637708
145PALB2NM_024675.3(PALB2): c.2587-?_*(1_?)deldeletionPathogenicGRCh38Chr 16, 23603458: 23626397
146PALB2NM_024675.3(PALB2): c.3351-?_*(1_?)deldeletionPathogenicGRCh38Chr 16, 23603458: 23603669
147BRIP1NM_032043.2(BRIP1): c.2447G> A (p.Trp816Ter)SNVPathogenicrs786204250GRCh37Chr 17, 59793357: 59793357
148BRCA2NM_000059.3(BRCA2): c.2743_2747delACTTG (p.Thr915Cysfs)deletionPathogenicrs786204752GRCh38Chr 13, 32337098: 32337102
149PALB2NM_024675.3(PALB2): c.2587-?_2748+?deldeletionLikely pathogenic, PathogenicChr na, -1: -1
150CHEK2NM_007194.3(CHEK2): c.(?_-1)_(*1_?)deldeletionPathogenicChr na, -1: -1
151CHEK2NM_007194.3(CHEK2): c.909-?_1095+?deldeletionPathogenicChr na, -1: -1
152PALB2NM_024675.3(PALB2): c.2470dupT (p.Cys824Leufs)duplicationPathogenicrs863224521GRCh37Chr 16, 23641005: 23641005
153PALB2NM_024675.3(PALB2): c.3114-?_3201+?deldeletionPathogenicChr na, -1: -1
154BRIP1NM_032043.2(BRIP1): c.1236delA (p.Val413Phefs)deletionPathogenicrs863224525GRCh37Chr 17, 59876565: 59876565
155BRIP1NM_032043.2(BRIP1): c.1343G> A (p.Trp448Ter)SNVPathogenicrs775171520GRCh37Chr 17, 59871088: 59871088
156BRIP1NM_032043.2(BRIP1): c.1383T> G (p.Tyr461Ter)SNVPathogenicrs587780875GRCh37Chr 17, 59871048: 59871048
157PALB2NM_024675.3(PALB2): c.3271C> T (p.Gln1091Ter)SNVPathogenicrs864622138GRCh38Chr 16, 23607943: 23607943
158BRIP1NM_032043.2(BRIP1): c.866delT (p.Val289Alafs)deletionPathogenicrs864622166GRCh38Chr 17, 61808519: 61808519
159BRIP1NM_032043.2(BRIP1): c.1474-?_1628+?deldeletionPathogenicChr na, -1: -1
160BARD1NM_000465.3(BARD1): c.627_628delAA (p.Lys209Asnfs)deletionLikely pathogenic, Pathogenicrs864622223GRCh38Chr 2, 214781246: 214781247
161BRIP1NM_032043.2(BRIP1): c.958delA (p.Ser320Valfs)deletionPathogenicrs864622236GRCh37Chr 17, 59878796: 59878796
162PALB2NM_024675.3(PALB2): c.3114-?_*(1_?)deldeletionPathogenicGRCh37Chr 16, 23614779: 23625412
163PALB2NM_024675.3(PALB2): c.3202-?_*(1_?)deldeletionPathogenicGRCh37Chr 16, 23614779: 23619333
164PALB2NM_024675.3(PALB2): c.860dupT (p.Ser288Lysfs)duplicationLikely pathogenic, Pathogenicrs864622301GRCh37Chr 16, 23647007: 23647007
165CHEK2NM_007194.3(CHEK2): c.480_483dupAGAA (p.Asp162Argfs)duplicationPathogenicrs864622453GRCh38Chr 22, 28725086: 28725089
166PALB2NM_024675.3(PALB2): c.3286_3289delAACCinsGTTAATGA (p.Asn1096Valfs)indelPathogenicrs587782337GRCh37Chr 16, 23619246: 23619249
167PALB2NM_024675.3(PALB2): c.93dupA (p.Leu32Thrfs)duplicationLikely pathogenic, Pathogenicrs864622498GRCh38Chr 16, 23638085: 23638085
168BRIP1NM_032043.2(BRIP1): c.2114_2118delAAGAA (p.Lys705Thrfs)deletionPathogenicrs864622611GRCh37Chr 17, 59821932: 59821936
169PALB2NM_024675.3(PALB2): c.761C> A (p.Ser254Ter)SNVPathogenicrs864622695GRCh38Chr 16, 23635785: 23635785
170PALB2NM_024675.3(PALB2): c.2391delA (p.Gln797Hisfs)deletionLikely pathogenic, Pathogenicrs515726086GRCh38Chr 16, 23629763: 23629763
171BRCA2NM_000059.3(BRCA2): c.8930delA (p.Tyr2977Phefs)deletionPathogenicrs869320799GRCh37Chr 13, 32953629: 32953629
172PALB2NM_024675.3(PALB2): c.2411_2412delCT (p.Ser804Cysfs)deletionLikely pathogenic, Pathogenicrs747148023GRCh37Chr 16, 23641063: 23641064
173BRCA1NM_007294.3(BRCA1): c.1140dupG (p.Lys381Glufs)duplicationLikely pathogenic, Pathogenicrs876659327GRCh37Chr 17, 41246408: 41246408
174BRIP1NM_032043.2(BRIP1): c.2990_2993delCAAA (p.Thr997Argfs)deletionLikely pathogenic, Pathogenicrs771028677GRCh37Chr 17, 59761414: 59761417
175BARD1NM_000465.3(BARD1): c.1172C> G (p.Ser391Ter)SNVPathogenicrs878853995GRCh37Chr 2, 215645426: 215645426
176BARD1NM_000465.3(BARD1): c.1569-?_*3030+?deldeletionPathogenicChr na, -1: -1
177CHEK2NM_007194.3(CHEK2): c.1072C> T (p.Gln358Ter)SNVPathogenicrs878854909GRCh37Chr 22, 29092912: 29092912
178CHEK2NM_007194.3(CHEK2): c.1188delT (p.Val397Phefs)deletionPathogenicrs753159426GRCh38Chr 22, 28695781: 28695781
179CHEK2NM_007194.3(CHEK2): c.208G> T (p.Glu70Ter)SNVPathogenicrs878854917GRCh37Chr 22, 29130502: 29130502
180PALB2NM_024675.3(PALB2): c.1369G> T (p.Glu457Ter)SNVPathogenicrs878855099GRCh38Chr 16, 23635177: 23635177
181PALB2NM_024675.3(PALB2): c.2079delT (p.His693Glnfs)deletionPathogenicrs878855105GRCh37Chr 16, 23641396: 23641396
182PALB2NM_024675.3(PALB2): c.2509G> T (p.Glu837Ter)SNVPathogenicrs587778587GRCh37Chr 16, 23640966: 23640966
183PALB2NM_024675.3(PALB2): c.2594C> G (p.Ser865Ter)SNVPathogenicrs746604683GRCh37Chr 16, 23637711: 23637711
184PALB2NM_024675.3(PALB2): c.3351-?_*297+?deldeletionPathogenicChr na, -1: -1
185PALB2NM_024675.3(PALB2): c.3420G> A (p.Trp1140Ter)SNVPathogenicrs878855118GRCh38Chr 16, 23603600: 23603600
186PALB2NM_024675.3(PALB2): c.79G> T (p.Glu27Ter)SNVPathogenicrs878855122GRCh37Chr 16, 23649420: 23649420
187PALB2NM_024675.3(PALB2): c.7G> T (p.Glu3Ter)SNVPathogenicrs878855123GRCh38Chr 16, 23641151: 23641151
188BRIP1NM_032043.2(BRIP1): c.1018_1019insCT (p.Leu340Profs)insertionPathogenicrs878855134GRCh37Chr 17, 59878735: 59878736
189BRIP1NM_032043.2(BRIP1): c.1697_1698insTATATCAAATTGATATTTCAACAAC (p.Lys567Ilefs)insertionPathogenicrs878855140GRCh38Chr 17, 61780936: 61780937
190BRIP1NM_032043.2(BRIP1): c.2138T> G (p.Leu713Ter)SNVPathogenicrs878855145GRCh37Chr 17, 59821912: 59821912
191BRIP1NM_032043.2(BRIP1): c.2479C> T (p.Gln827Ter)SNVPathogenicrs786203898GRCh37Chr 17, 59793325: 59793325
192BRIP1NM_032043.2(BRIP1): c.2684_2687delCCAT (p.Ser895Terfs)deletionPathogenicrs760551339GRCh38Chr 17, 61686054: 61686057
193BRIP1NM_032043.2(BRIP1): c.890_891insT (p.Lys297Asnfs)insertionPathogenicrs878855159GRCh38Chr 17, 61808494: 61808495
194BRCA1NM_007294.3(BRCA1): c.2331_2332dupTG (p.Gly778Valfs)duplicationPathogenicrs431825390GRCh38Chr 17, 43093199: 43093200
195BRCA2NM_000059.3(BRCA2): c.6466_6469delTCTC (p.Ser2156Asnfs)deletionPathogenicrs879255330GRCh37Chr 13, 32914958: 32914961
196PALB2NM_024675.3(PALB2): c.3202-?_3350+?deldeletionPathogenicChr na, -1: -1
197BRCA1NM_007294.3(BRCA1): c.65delT (p.Leu22Terfs)deletionPathogenicrs80357803GRCh37Chr 17, 41276049: 41276049
198BRCA1NM_007294.3(BRCA1): c.74_75delCC (p.Pro25Hisfs)deletionPathogenicrs80357633GRCh38Chr 17, 43124022: 43124023
199BRCA1NM_007294.3(BRCA1): c.1501_1504delAAAT (p.Lys501Terfs)deletionPathogenicrs80357632GRCh37Chr 17, 41246044: 41246047
200BRCA1NM_007294.3(BRCA1): c.1826delA (p.Asn609Ilefs)deletionPathogenicrs80357736GRCh37Chr 17, 41245722: 41245722
201BRCA1NM_007294.3(BRCA1): c.4038_4039delAA (p.Gly1348Asnfs)deletionPathogenicrs273900721GRCh37Chr 17, 41243509: 41243510
202BRCA1NM_007294.3(BRCA1): c.5276delA (p.Lys1759Argfs)deletionPathogenicrs80357732GRCh37Chr 17, 41209070: 41209070
203BRCA2NM_000059.3(BRCA2): c.541delT (p.Ser181Leufs)deletionPathogenicrs276174857GRCh37Chr 13, 32900660: 32900660
204BRCA2NM_000059.3(BRCA2): c.2085_2089delGGAAA (p.Glu696Thrfs)deletionPathogenicrs80359321GRCh37Chr 13, 32910577: 32910581
205BRCA2NM_000059.3(BRCA2): c.3293delA (p.Asn1098Ilefs)deletionPathogenicrs690016541GRCh37Chr 13, 32911785: 32911785
206BRCA2NM_000059.3(BRCA2): c.3295delT (p.Ser1099Glnfs)deletionPathogenicrs80359383GRCh37Chr 13, 32911787: 32911787
207BRCA2NM_000059.3(BRCA2): c.3639delA (p.Val1214Trpfs)deletionPathogenicrs80359394GRCh37Chr 13, 32912131: 32912131
208BRCA2NM_000059.3(BRCA2): c.3957_3960delTGAA (p.Asn1319Lysfs)deletionPathogenicrs80359417GRCh37Chr 13, 32912449: 32912452
209BRCA2NM_000059.3(BRCA2): c.5132_5135delTAGG (p.Val1711Glufs)deletionPathogenicrs80359486GRCh37Chr 13, 32913624: 32913627
210BRCA2NM_000059.3(BRCA2): c.5720_5723delCTCT (p.Ser1907Terfs)deletionPathogenicrs276174862GRCh37Chr 13, 32914212: 32914215
211BRCA2NM_000059.3(BRCA2): c.5891delA (p.Lys1964Serfs)deletionPathogenicrs276174864GRCh37Chr 13, 32914383: 32914383
212BRCA2NM_000059.3(BRCA2): c.6239delT (p.Leu2080Terfs)deletionPathogenicrs80359569GRCh37Chr 13, 32914731: 32914731
213BRCA2NM_000059.3(BRCA2): c.6434delA (p.Asn2145Ilefs)deletionPathogenicrs80359587GRCh37Chr 13, 32914926: 32914926
214BRCA2NM_000059.3(BRCA2): c.7109_7110delAA (p.Lys2370Ilefs)deletionPathogenicrs80359638GRCh37Chr 13, 32929099: 32929100
215BRCA2NM_000059.3(BRCA2): c.8648delC (p.Pro2883Hisfs)deletionPathogenicrs276174910GRCh38Chr 13, 32376685: 32376685
216BRCA2NM_000059.3(BRCA2): c.9429_9430delTT (p.Ser3144Cysfs)deletionPathogenicrs80359762GRCh38Chr 13, 32394861: 32394862
217BRCA2NM_000059.3(BRCA2): c.3739delA (p.Ile1247Leufs)deletionPathogenicrs886040494GRCh38Chr 13, 32338094: 32338094
218ATMATM, IVS61DS, 2-BP INS, +2TAinsertionPathogenicChr na, -1: -1
219BRCA1NM_007294.3(BRCA1): c.1016delA (p.Lys339Argfs)deletionPathogenicrs80357618GRCh37Chr 17, 41246532: 41246532
220BRCA1NM_007294.3(BRCA1): c.1018delG (p.Val340Terfs)deletionPathogenicrs80357774GRCh37Chr 17, 41246530: 41246530
221BRCA1NM_007294.3(BRCA1): c.1121delC (p.Thr374Asnfs)deletionPathogenicrs80357612GRCh37Chr 17, 41246427: 41246427
222BRCA1NM_007294.3(BRCA1): c.135-1G> TSNVPathogenicrs80358158GRCh37Chr 17, 41258551: 41258551
223BRCA1NM_007294.3(BRCA1): c.1360_1361delAG (p.Ser454Terfs)deletionPathogenicrs80357969GRCh37Chr 17, 41246187: 41246188
224BRCA1NM_007294.3(BRCA1): c.1480C> T (p.Gln494Ter)SNVPathogenicrs80357010GRCh37Chr 17, 41246068: 41246068
225BRCA1NM_007294.3(BRCA1): c.1510delC (p.Arg504Valfs)deletionPathogenicrs80357908GRCh37Chr 17, 41246038: 41246038
226BRCA1NM_007294.3(BRCA1): c.212+1G> ASNVPathogenicrs80358042GRCh37Chr 17, 41258472: 41258472
227BRCA1NM_007294.3(BRCA1): c.2158G> T (p.Glu720Ter)SNVPathogenicrs80356875GRCh37Chr 17, 41245390: 41245390
228BRCA1NM_007294.3(BRCA1): c.2210_2211delCA (p.Thr737Serfs)deletionPathogenicrs80357654GRCh37Chr 17, 41245337: 41245338
229BRCA1NM_007294.3(BRCA1): c.2269delG (p.Val757Phefs)deletionPathogenicrs80357583GRCh37Chr 17, 41245279: 41245279
230BRCA1NM_007294.3(BRCA1): c.2299delA (p.Ser767Alafs)deletionPathogenicrs80357786GRCh37Chr 17, 41245249: 41245249
231BRCA1NM_007294.3(BRCA1): c.2515delC (p.His839Thrfs)deletionPathogenicrs80357607GRCh37Chr 17, 41245033: 41245033
232BRCA1NM_007294.3(BRCA1): c.2563C> T (p.Gln855Ter)SNVPathogenicrs80357131GRCh37Chr 17, 41244985: 41244985
233BRCA1NM_007294.3(BRCA1): c.2603C> G (p.Ser868Ter)SNVPathogenicrs80356925GRCh37Chr 17, 41244945: 41244945
234BRCA1NM_007294.3(BRCA1): c.2710G> T (p.Glu904Ter)SNVPathogenicrs80357035GRCh37Chr 17, 41244838: 41244838
235BRCA1NM_007294.3(BRCA1): c.302-2A> CSNVPathogenicrs80358011GRCh37Chr 17, 41256280: 41256280
236BRCA1NM_007294.3(BRCA1): c.302-3C> GSNVLikely pathogenic, Pathogenicrs80358051GRCh37Chr 17, 41256281: 41256281
237BRCA1NM_007294.3(BRCA1): c.3112G> T (p.Glu1038Ter)SNVPathogenicrs80357161GRCh37Chr 17, 41244436: 41244436
238BRCA1NM_007294.3(BRCA1): c.3358_3359delGT (p.Val1120Terfs)deletionPathogenicrs80357945GRCh37Chr 17, 41244189: 41244190
239BRCA1NM_007294.3(BRCA1): c.3389C> G (p.Ser1130Ter)SNVPathogenicrs80357405GRCh37Chr 17, 41244159: 41244159
240BRCA1NM_007294.3(BRCA1): c.3442delG (p.Glu1148Argfs)deletionPathogenicrs80357808GRCh37Chr 17, 41244106: 41244106
241BRCA1NM_007294.3(BRCA1): c.3485delA (p.Asp1162Valfs)deletionPathogenicrs80357509GRCh37Chr 17, 41244063: 41244063
242BRCA1NM_007294.3(BRCA1): c.3612delA (p.Ala1206Profs)deletionPathogenicrs80357980GRCh37Chr 17, 41243936: 41243936
243BRCA1NM_007294.3(BRCA1): c.3648dupA (p.Ser1217Ilefs)duplicationPathogenicrs80357902GRCh37Chr 17, 41243900: 41243900
244BRCA1NM_007294.3(BRCA1): c.3689T> G (p.Leu1230Ter)SNVPathogenicrs80357162GRCh37Chr 17, 41243859: 41243859
245BRCA1NM_007294.3(BRCA1): c.3700_3704delGTAAA (p.Val1234Glnfs)deletionPathogenicrs80357609GRCh37Chr 17, 41243844: 41243848
246BRCA1NM_007294.3(BRCA1): c.3759_3760delTA (p.Lys1254Glufs)deletionPathogenicrs80357520GRCh37Chr 17, 41243788: 41243789
247BRCA1NM_007294.3(BRCA1): c.3868A> T (p.Lys1290Ter)SNVPathogenicrs80357254GRCh37Chr 17, 41243680: 41243680
248BRCA1NM_007294.3(BRCA1): c.3937C> T (p.Gln1313Ter)SNVPathogenicrs80357318GRCh37Chr 17, 41243611: 41243611
249BRCA1NM_007294.3(BRCA1): c.3991C> T (p.Gln1331Ter)SNVPathogenicrs397507224GRCh37Chr 17, 41243557: 41243557
250BRCA1NM_007294.3(BRCA1): c.4015G> T (p.Glu1339Ter)SNVPathogenicrs80357021GRCh37Chr 17, 41243533: 41243533
251BRCA1NM_007294.3(BRCA1): c.4035delA (p.Glu1346Lysfs)deletionPathogenicrs80357711GRCh37Chr 17, 41243513: 41243513
252BRCA1NM_007294.3(BRCA1): c.4097-1G> ASNVPathogenicrs80358070GRCh37Chr 17, 41243050: 41243050
253BRCA1NM_007294.3(BRCA1): c.4116_4117delTG (p.Cys1372Terfs)deletionPathogenicrs80357804GRCh37Chr 17, 41243029: 41243030
254BRCA1NM_007294.3(BRCA1): c.4120_4121delAG (p.Ser1374Terfs)deletionPathogenicrs80357787GRCh37Chr 17, 41243025: 41243026
255BRCA1NM_007294.3(BRCA1): c.4148C> G (p.Ser1383Ter)SNVPathogenicrs80357071GRCh37Chr 17, 41242998: 41242998
256BRCA1NM_007294.3(BRCA1): c.4185+2_4185+22del21insAindelPathogenicrs273900724GRCh37Chr 17, 41242939: 41242959
257BRCA1NM_007294.3(BRCA1): c.4243delG (p.Glu1415Lysfs)deletionPathogenicrs80357981GRCh37Chr 17, 41234535: 41234535
258BRCA1NM_007294.3(BRCA1): c.4251_4252delGT (p.Leu1418Argfs)deletionPathogenicrs80357977GRCh37Chr 17, 41234526: 41234527
259BRCA1NM_007294.3(BRCA1): c.4391_4393delCTAinsTT (p.Pro1464Leufs)indelPathogenicrs273900730GRCh37Chr 17, 41228596: 41228598
260BRCA1NM_007294.3(BRCA1): c.4391delC (p.Pro1464Leufs)deletionPathogenicrs80357916GRCh37Chr 17, 41228598: 41228598
261BRCA1NM_007294.3(BRCA1): c.4393delA (p.Ile1465Terfs)deletionPathogenicrs397507230GRCh37Chr 17, 41228596: 41228596
262BRCA1NM_007294.3(BRCA1): c.4482_4483delAA (p.Arg1495Valfs)deletionPathogenicrs80357854GRCh37Chr 17, 41228506: 41228507
263BRCA1NM_007294.3(BRCA1): c.4484+1G> ASNVPathogenicrs80358063GRCh37Chr 17, 41228504: 41228504
264BRCA1NM_007294.3(BRCA1): c.4675G> A (p.Glu1559Lys)SNVPathogenicrs80356988GRCh37Chr 17, 41226348: 41226348
265BRCA1NM_007294.3(BRCA1): c.4675G> C (p.Glu1559Gln)SNVLikely pathogenic, Pathogenicrs80356988GRCh37Chr 17, 41226348: 41226348
266BRCA1NM_007294.3(BRCA1): c.4749_4750delAG (p.Arg1583Serfs)deletionPathogenicrs80357641GRCh37Chr 17, 41223181: 41223182
267BRCA1NM_007294.3(BRCA1): c.4986+1G> TSNVPathogenicrs80358162GRCh37Chr 17, 41222944: 41222944
268BRCA1NM_007294.3(BRCA1): c.5035_5039delCTAAT (p.Leu1679Tyrfs)deletionPathogenicrs80357623GRCh37Chr 17, 41219660: 41219664
269BRCA1NM_007294.3(BRCA1): c.5068A> T (p.Lys1690Ter)SNVPathogenicrs397507239GRCh37Chr 17, 41219631: 41219631
270BRCA1NM_007294.3(BRCA1): c.5074+1G> ASNVPathogenicrs80358053GRCh37Chr 17, 41219624: 41219624
271BRCA1NM_007294.3(BRCA1): c.5074+1G> TSNVLikely pathogenic, Pathogenicrs80358053GRCh37Chr 17, 41219624: 41219624
272BRCA1NM_007294.3(BRCA1): c.5074G> A (p.Asp1692Asn)SNVLikely pathogenic, Pathogenicrs80187739GRCh37Chr 17, 41219625: 41219625
273BRCA1NM_007294.3(BRCA1): c.5074G> C (p.Asp1692His)SNVLikely pathogenic, Pathogenicrs80187739GRCh37Chr 17, 41219625: 41219625
274BRCA1NM_007294.3(BRCA1): c.5117G> A (p.Gly1706Glu)SNVPathogenicrs80356860GRCh37Chr 17, 41215926: 41215926
275BRCA1NM_007294.3(BRCA1): c.5152+1G> CSNVPathogenicrs80358094GRCh37Chr 17, 41215890: 41215890
276BRCA1NM_007294.3(BRCA1): c.5153-1G> CSNVPathogenicrs80358137GRCh37Chr 17, 41215391: 41215391
277BRCA1NM_007294.3(BRCA1): c.5194-2A> GSNVLikely pathogenic, Pathogenicrs80358069GRCh37Chr 17, 41209154: 41209154
278BRCA1NM_007294.3(BRCA1): c.5277+1G> ASNVPathogenicrs80358150GRCh37Chr 17, 41209068: 41209068
279BRCA1NM_007294.3(BRCA1): c.5289dupG (p.Leu1764Alafs)duplicationPathogenicrs80357886GRCh37Chr 17, 41203123: 41203123
280BRCA1NM_007294.3(BRCA1): c.5297T> G (p.Ile1766Ser)SNVPathogenicrs80357463GRCh37Chr 17, 41203115: 41203115
281BRCA1NM_007294.3(BRCA1): c.5346G> A (p.Trp1782Ter)SNVPathogenicrs80357284GRCh37Chr 17, 41201198: 41201198
282BRCA1NM_007294.3(BRCA1): c.5417delC (p.Pro1806Glnfs)deletionPathogenicrs80357558GRCh37Chr 17, 41199710: 41199710
283BRCA1NM_007294.3(BRCA1): c.5434C> G (p.Pro1812Ala)SNVLikely pathogenic, Pathogenicrs1800751GRCh37Chr 17, 41199693: 41199693
284BRCA1NM_007294.3(BRCA1): c.5453A> G (p.Asp1818Gly)SNVLikely pathogenic, Pathogenicrs80357477GRCh37Chr 17, 41199674: 41199674
285BRCA1NM_007294.3(BRCA1): c.547+2T> ASNVPathogenicrs80358047GRCh37Chr 17, 41251790: 41251790
286BRCA1NM_007294.3(BRCA1): c.783T> G (p.Tyr261Ter)SNVPathogenicrs80357321GRCh37Chr 17, 41246765: 41246765
287BRCA1NM_007294.3(BRCA1): c.85G> T (p.Glu29Ter)SNVPathogenicrs80357443GRCh37Chr 17, 41267792: 41267792
288BRCA1NM_007294.3(BRCA1): c.929delA (p.Gln310Argfs)deletionPathogenicrs80357844GRCh37Chr 17, 41246619: 41246619
289BRCA1NM_007294.3(BRCA1): c.952_1015del64 (p.His318Argfs)deletionPathogenicrs80359872GRCh37Chr 17, 41246533: 41246596
290BRCA2NM_000059.3(BRCA2): c.1029delA (p.Lys343Asnfs)deletionPathogenicrs80359260GRCh37Chr 13, 32906644: 32906644
291BRCA2NM_000059.3(BRCA2): c.1238delT (p.Leu413Hisfs)deletionPathogenicrs80359271GRCh37Chr 13, 32906853: 32906853
292BRCA2NM_000059.3(BRCA2): c.1593dupA (p.Glu532Argfs)duplicationPathogenicrs397507272GRCh37Chr 13, 32907208: 32907208
293BRCA2NM_000059.3(BRCA2): c.1832C> A (p.Ser611Ter)SNVPathogenicrs80358474GRCh37Chr 13, 32907447: 32907447
294BRCA2NM_000059.3(BRCA2): c.2036delA (p.Asn679Ilefs)deletionPathogenicrs80359318GRCh37Chr 13, 32910528: 32910528
295BRCA2NM_000059.3(BRCA2): c.2092delC (p.Leu698Tyrfs)deletionPathogenicrs80359322GRCh37Chr 13, 32910584: 32910584
296BRCA2NM_000059.3(BRCA2): c.2231C> G (p.Ser744Ter)SNVPathogenicrs397507282GRCh37Chr 13, 32910723: 32910723
297BRCA2NM_000059.3(BRCA2): c.2409T> G (p.Tyr803Ter)SNVPathogenicrs80358504GRCh37Chr 13, 32910901: 32910901
298BRCA2NM_000059.3(BRCA2): c.274C> T (p.Gln92Ter)SNVPathogenicrs80358529GRCh37Chr 13, 32893420: 32893420
299BRCA2NM_000059.3(BRCA2): c.2979G> A (p.Trp993Ter)SNVPathogenicrs80358544GRCh37Chr 13, 32911471: 32911471
300BRCA2NM_000059.3(BRCA2): c.3158T> G (p.Leu1053Ter)SNVPathogenicrs41293477GRCh37Chr 13, 32911650: 32911650
301BRCA2NM_000059.3(BRCA2): c.3160_3163delGATA (p.Asp1054Ilefs)deletionPathogenicrs80359371GRCh37Chr 13, 32911652: 32911655
302BRCA2NM_000059.3(BRCA2): c.3689delC (p.Ser1230Leufs)deletionPathogenicrs80359398GRCh37Chr 13, 32912181: 32912181
303BRCA2NM_000059.3(BRCA2): c.3847_3848delGT (p.Val1283Lysfs)deletionPathogenicrs80359405GRCh37Chr 13, 32912339: 32912340
304BRCA2NM_000059.3(BRCA2): c.396T> A (p.Cys132Ter)SNVPathogenicrs397507320GRCh37Chr 13, 32899292: 32899292
305BRCA2NM_000059.3(BRCA2): c.3delG (p.Met1Ilefs)deletionPathogenicrs80359418GRCh37Chr 13, 32890600: 32890600
306BRCA2NM_000059.3(BRCA2): c.407delA (p.Asn136Ilefs)deletionPathogenicrs80359425GRCh37Chr 13, 32899303: 32899303
307BRCA2NM_000059.3(BRCA2): c.4092_4093delAT (p.Ile1364Metfs)deletionPathogenicrs80359426GRCh37Chr 13, 32912584: 32912585
308BRCA2NM_000059.3(BRCA2): c.4243G> T (p.Glu1415Ter)SNVPathogenicrs397507327GRCh37Chr 13, 32912735: 32912735
309BRCA2NM_000059.3(BRCA2): c.4276dupA (p.Thr1426Asnfs)duplicationPathogenicrs80359438GRCh37Chr 13, 32912768: 32912768
310BRCA2NM_000059.3(BRCA2): c.4405_4409delGACAT (p.Asp1469Lysfs)deletionPathogenicrs397507331GRCh37Chr 13, 32912897: 32912901
311BRCA2NM_000059.3(BRCA2): c.4414_4415delAA (p.Lys1472Glufs)deletionPathogenicrs397507332GRCh37Chr 13, 32912906: 32912907
312BRCA2NM_000059.3(BRCA2): c.4449delA (p.Asp1484Thrfs)deletionPathogenicrs80359448GRCh37Chr 13, 32912941: 32912941
313BRCA2NM_000059.3(BRCA2): c.4712_4713delAG (p.Glu1571Glyfs)deletionPathogenicrs80359464GRCh37Chr 13, 32913204: 32913205
314BRCA2NM_000059.3(BRCA2): c.476-1G> ASNVPathogenicrs397507340GRCh37Chr 13, 32900378: 32900378
315BRCA2NM_000059.3(BRCA2): c.476-2A> GSNVPathogenicrs81002853GRCh37Chr 13, 32900377: 32900377
316BRCA2NM_000059.3(BRCA2): c.5035delA (p.Thr1679Leufs)deletionPathogenicrs80359477GRCh37Chr 13, 32913527: 32913527
317BRCA2NM_000059.3(BRCA2): c.518delG (p.Gly173Valfs)deletionPathogenicrs80359492GRCh37Chr 13, 32900637: 32900637
318BRCA2NM_000059.3(BRCA2): c.5238dupT (p.Asn1747Terfs)duplicationPathogenicrs80359499GRCh37Chr 13, 32913730: 32913730
319BRCA2NM_000059.3(BRCA2): c.5266_5269delGTAT (p.Val1756Ilefs)deletionPathogenicrs80359501GRCh37Chr 13, 32913758: 32913761
320BRCA2NM_000059.3(BRCA2): c.5303_5304delTT (p.Leu1768Argfs)deletionPathogenicrs80359505GRCh37Chr 13, 32913795: 32913796
321BRCA2NM_000059.3(BRCA2): c.5351delA (p.Asn1784Thrfs)deletionPathogenicrs80359509GRCh37Chr 13, 32913843: 32913843
322BRCA2NM_000059.3(BRCA2): c.5410_5411delGT (p.Val1804Lysfs)deletionPathogenicrs80359512GRCh37Chr 13, 32913902: 32913903
323BRCA2NM_000059.3(BRCA2): c.5471dupA (p.Asn1824Lysfs)duplicationPathogenicrs80359515GRCh37Chr 13, 32913963: 32913963
324BRCA2NM_000059.3(BRCA2): c.5595_5596delAT (p.Phe1866Tyrfs)deletionPathogenicrs80359524GRCh37Chr 13, 32914087: 32914088
325BRCA2NM_000059.3(BRCA2): c.5614A> T (p.Lys1872Ter)SNVPathogenicrs80358783GRCh37Chr 13, 32914106: 32914106
326BRCA2NM_000059.3(BRCA2): c.5621_5624delTTAA (p.Ile1874Argfs)deletionPathogenicrs80359526GRCh37Chr 13, 32914113: 32914116
327BRCA2NM_000059.3(BRCA2): c.574_575delAT (p.Met192Valfs)deletionPathogenicrs80359533GRCh37Chr 13, 32900693: 32900694
328BRCA2NM_000059.3(BRCA2): c.5782G> T (p.Glu1928Ter)SNVPathogenicrs56253082GRCh37Chr 13, 32914274: 32914274
329BRCA2NM_000059.3(BRCA2): c.582G> A (p.Trp194Ter)SNVPathogenicrs80358810GRCh37Chr 13, 32900701: 32900701
330BRCA2NM_000059.3(BRCA2): c.5851_5854delAGTT (p.Ser1951Trpfs)deletionPathogenicrs80359543GRCh37Chr 13, 32914343: 32914346
331BRCA2NM_000059.3(BRCA2): c.5909C> A (p.Ser1970Ter)SNVPathogenicrs80358824GRCh37Chr 13, 32914401: 32914401
332BRCA2NM_000059.3(BRCA2): c.6206T> G (p.Leu2069Ter)SNVPathogenicrs80358859GRCh37Chr 13, 32914698: 32914698
333BRCA2NM_000059.3(BRCA2): c.6267_6269delGCAinsC (p.Glu2089Aspfs)indelPathogenicrs276174868GRCh37Chr 13, 32914759: 32914761
334BRCA2NM_000059.3(BRCA2): c.631G> C (p.Val211Leu)SNVPathogenicrs80358871GRCh37Chr 13, 32900750: 32900750
335BRCA2NM_000059.3(BRCA2): c.6434_6441delATAATCAC (p.Asn2145Ilefs)deletionPathogenicrs397507371GRCh37Chr 13, 32914926: 32914933
336BRCA2NM_000059.3(BRCA2): c.6444dupT (p.Ile2149Tyrfs)duplicationPathogenicrs80359590GRCh37Chr 13, 32914936: 32914936
337BRCA2NM_000059.3(BRCA2): c.6486_6489delACAA (p.Lys2162Asnfs)deletionPathogenicrs80359598GRCh37Chr 13, 32914978: 32914981
338BRCA2NM_000059.3(BRCA2): c.6535_6536insA (p.Val2179Aspfs)insertionPathogenicrs80359601GRCh37Chr 13, 32915027: 32915028
339BRCA2NM_000059.3(BRCA2): c.6641dupC (p.Tyr2215Leufs)duplicationPathogenicrs80359613GRCh37Chr 13, 32915133: 32915133
340BRCA2NM_000059.3(BRCA2): c.6644_6647delACTC (p.Tyr2215Serfs)deletionPathogenicrs80359616GRCh37Chr 13, 32915136: 32915139
341BRCA2NM_000059.3(BRCA2): c.6724_6725delGA (p.Asp2242Phefs)deletionPathogenicrs397507375GRCh37Chr 13, 32915216: 32915217
342BRCA2NM_000059.3(BRCA2): c.688A> T (p.Lys230Ter)SNVPathogenicrs80358913GRCh37Chr 13, 32905062: 32905062
343BRCA2NM_000059.3(BRCA2): c.6941delC (p.Thr2314Lysfs)deletionPathogenicrs80359628GRCh37Chr 13, 32920967: 32920967
344BRCA2NM_000059.3(BRCA2): c.6944_6947delTAAA (p.Ile2315Lysfs)deletionPathogenicrs80359629GRCh37Chr 13, 32920970: 32920973
345BRCA2NM_000059.3(BRCA2): c.700delT (p.Ser234Profs)deletionPathogenicrs80359630GRCh37Chr 13, 32905074: 32905074
346BRCA2NM_000059.3(BRCA2): c.7133C> G (p.Ser2378Ter)SNVPathogenicrs276174889GRCh37Chr 13, 32929123: 32929123
347BRCA2NM_000059.3(BRCA2): c.7258G> T (p.Glu2420Ter)SNVPathogenicrs397507385GRCh37Chr 13, 32929248: 32929248
348BRCA2NM_000059.3(BRCA2): c.7379_7382delACAA (p.Asn2460Thrfs)deletionPathogenicrs80359648GRCh37Chr 13, 32929369: 32929372
349BRCA2NM_000059.3(BRCA2): c.7412_7421delCAAAGTGTGA (p.Thr2471Lysfs)deletionPathogenicrs80359649GRCh37Chr 13, 32929402: 32929411
350BRCA2NM_000059.3(BRCA2): c.7414_7415delAA (p.Lys2472Valfs)deletionPathogenicrs80359650GRCh37Chr 13, 32929404: 32929405
351BRCA2NM_000059.3(BRCA2): c.7419_7420delTG (p.Cys2473Terfs)deletionPathogenicrs80359651GRCh37Chr 13, 32929409: 32929410
352BRCA2NM_000059.3(BRCA2): c.7567_7568delCT (p.Leu2523Glufs)deletionPathogenicrs80359664GRCh37Chr 13, 32930696: 32930697
353BRCA2NM_000059.3(BRCA2): c.756_757delCA (p.Asp252Glufs)deletionPathogenicrs80359662GRCh37Chr 13, 32905130: 32905131
354BRCA2NM_000059.3(BRCA2): c.7673_7674delAG (p.Glu2558Valfs)deletionPathogenicrs80359672GRCh37Chr 13, 32931934: 32931935
355BRCA2NM_000059.3(BRCA2): c.7758G> A (p.Trp2586Ter)SNVPathogenicrs80359004GRCh37Chr 13, 32932019: 32932019
356BRCA2NM_000059.3(BRCA2): c.7857G> A (p.Trp2619Ter)SNVPathogenicrs80359011GRCh37Chr 13, 32936711: 32936711
357BRCA2NM_000059.3(BRCA2): c.7913_7917delTTCCT (p.Phe2638Terfs)deletionPathogenicrs80359686GRCh37Chr 13, 32936767: 32936771
358BRCA2NM_000059.3(BRCA2): c.7963C> T (p.Gln2655Ter)SNVPathogenicrs397507395GRCh37Chr 13, 32936817: 32936817
359BRCA2NM_000059.3(BRCA2): c.7974C> G (p.Tyr2658Ter)SNVPathogenicrs80359025GRCh37Chr 13, 32936828: 32936828
360BRCA2NM_000059.3(BRCA2): c.8168A> G (p.Asp2723Gly)SNVPathogenicrs41293513GRCh37Chr 13, 32937507: 32937507
361BRCA2NM_000059.3(BRCA2): c.8322dupT (p.Met2775Tyrfs)duplicationPathogenicrs80359706GRCh37Chr 13, 32937661: 32937661
362BRCA2NM_000059.3(BRCA2): c.8331+1G> ASNVLikely pathogenic, Pathogenicrs81002837GRCh37Chr 13, 32937671: 32937671
363BRCA2NM_000059.3(BRCA2): c.8486A> G (p.Gln2829Arg)SNVLikely pathogenic, Pathogenicrs80359100GRCh37Chr 13, 32944693: 32944693
364BRCA2NM_000059.3(BRCA2): c.8501delC (p.Thr2834Asnfs)deletionPathogenicrs80359712GRCh37Chr 13, 32945106: 32945106
365BRCA2NM_000059.3(BRCA2): c.8548_8551delGAAG (p.Glu2850Glnfs)deletionPathogenicrs397507406GRCh37Chr 13, 32945153: 32945156
366BRCA2NM_000059.3(BRCA2): c.8585dupT (p.Glu2863Argfs)duplicationPathogenicrs80359720GRCh37Chr 13, 32945190: 32945190
367BRCA2NM_000059.3(BRCA2): c.8633-2A> GSNVPathogenicrs81002886GRCh37Chr 13, 32950805: 32950805
368BRCA2NM_000059.3(BRCA2): c.8695C> T (p.Gln2899Ter)SNVPathogenicrs397507411GRCh37Chr 13, 32950869: 32950869
369BRCA2NM_000059.3(BRCA2): c.8869C> T (p.Gln2957Ter)SNVPathogenicrs276174913GRCh37Chr 13, 32953568: 32953568
370BRCA2NM_000059.3(BRCA2): c.8951C> G (p.Ser2984Ter)SNVPathogenicrs80359146GRCh37Chr 13, 32953650: 32953650
371BRCA2NM_000059.3(BRCA2): c.8953+1G> TSNVPathogenicrs81002882GRCh37Chr 13, 32953653: 32953653
372BRCA2NM_000059.3(BRCA2): c.9076C> T (p.Gln3026Ter)SNVPathogenicrs80359159GRCh37Chr 13, 32954009: 32954009
373BRCA2NM_000059.3(BRCA2): c.9097delA (p.Thr3033Leufs)deletionPathogenicrs397507420GRCh37Chr 13, 32954030: 32954030
374BRCA2NM_000059.3(BRCA2): c.9294C> A (p.Tyr3098Ter)SNVPathogenicrs80359200GRCh37Chr 13, 32968863: 32968863
375BRCA2NM_000059.3(BRCA2): c.9380G> A (p.Trp3127Ter)SNVPathogenicrs80359211GRCh37Chr 13, 32968949: 32968949
376BRCA2NM_000059.3(BRCA2): c.9401delG (p.Gly3134Alafs)deletionPathogenicrs80359759GRCh37Chr 13, 32968970: 32968970
377BRCA2NM_000059.3(BRCA2): c.9435_9436delGT (p.Ser3147Cysfs)deletionPathogenicrs80359763GRCh37Chr 13, 32969004: 32969005
378BRCA2NM_000059.3(BRCA2): c.9580_9581delCC (p.Pro3194Asnfs)deletionPathogenicrs80359771GRCh37Chr 13, 32971113: 32971114
379BRCA2NM_000059.3(BRCA2): c.9599C> G (p.Ser3200Ter)SNVPathogenicrs80359230GRCh37Chr 13, 32971132: 32971132
380BRCA2NM_000059.3(BRCA2): c.5482_5486delAAATT (p.Lys1828Valfs)deletionPathogenicrs80359516GRCh37Chr 13, 32913974: 32913978
381BRIP1NM_032043.2(BRIP1): c.139C> G (p.Pro47Ala)SNVLikely pathogenic, Pathogenicrs28903098GRCh37Chr 17, 59937223: 59937223
382BRIP1NM_032043.2(BRIP1): c.2392C> T (p.Arg798Ter)SNVPathogenicrs137852986GRCh37Chr 17, 59793412: 59793412
383BRCA2NM_000059.3(BRCA2): c.100G> T (p.Glu34Ter)SNVPathogenicrs80358391GRCh37Chr 13, 32893246: 32893246
384BRCA2NM_000059.3(BRCA2): c.1097dupT (p.Leu366Phefs)duplicationPathogenicrs397507570GRCh37Chr 13, 32906712: 32906712
385BRCA2NM_000059.3(BRCA2): c.10G> T (p.Gly4Ter)SNVPathogenicrs397507571GRCh37Chr 13, 32890607: 32890607
386BRCA2NM_000059.3(BRCA2): c.1103C> A (p.Ser368Ter)SNVPathogenicrs80358407GRCh37Chr 13, 32906718: 32906718
387BRCA2NM_000059.3(BRCA2): c.1117C> T (p.Gln373Ter)SNVPathogenicrs397507572GRCh37Chr 13, 32906732: 32906732
388BRCA2NM_000059.3(BRCA2): c.1128delT (p.Phe376Leufs)deletionPathogenicrs80359263GRCh37Chr 13, 32906743: 32906743
389BRCA2NM_000059.3(BRCA2): c.1147delA (p.Ile383Serfs)deletionPathogenicrs80359265GRCh37Chr 13, 32906762: 32906762
390BRCA2NM_000059.3(BRCA2): c.1153A> T (p.Lys385Ter)SNVPathogenicrs80358411GRCh37Chr 13, 32906768: 32906768
391BRCA2NM_000059.3(BRCA2): c.115delG (p.Ala39Leufs)deletionPathogenicrs397507573GRCh37Chr 13, 32893261: 32893261
392BRCA2NM_000059.3(BRCA2): c.1202C> G (p.Ser401Ter)SNVPathogenicrs80358413GRCh37Chr 13, 32906817: 32906817
393BRCA2NM_000059.3(BRCA2): c.1219delC (p.Gln407Argfs)deletionPathogenicrs80359267GRCh37Chr 13, 32906834: 32906834
394BRCA2NM_000059.3(BRCA2): c.1225delG (p.Glu409Argfs)deletionPathogenicrs80359268GRCh37Chr 13, 32906840: 32906840
395BRCA2NM_000059.3(BRCA2): c.1233dupA (p.Pro412Thrfs)duplicationPathogenicrs80359270GRCh37Chr 13, 32906848: 32906848
396BRCA2NM_000059.3(BRCA2): c.1261C> T (p.Gln421Ter)SNVPathogenicrs80358419GRCh37Chr 13, 32906876: 32906876
397BRCA2NM_000059.3(BRCA2): c.1278delA (p.Asp427Thrfs)deletionPathogenicrs80359274GRCh37Chr 13, 32906893: 32906893
398BRCA2NM_000059.3(BRCA2): c.128delA (p.Asn43Ilefs)deletionPathogenicrs80359275GRCh37Chr 13, 32893274: 32893274
399BRCA2NM_000059.3(BRCA2): c.1300_1303delAAAA (p.Lys434Glufs)deletionPathogenicrs397507577GRCh37Chr 13, 32906915: 32906918
400BRCA2NM_000059.3(BRCA2): c.1307delA (p.Lys436Argfs)deletionPathogenicrs80359278GRCh37Chr 13, 32906922: 32906922
401BRCA2NM_000059.3(BRCA2): c.1327G> T (p.Glu443Ter)SNVPathogenicrs397507579GRCh37Chr 13, 32906942: 32906942
402BRCA2NM_000059.3(BRCA2): c.1362delA (p.Lys454Asnfs)deletionPathogenicrs397507582GRCh37Chr 13, 32906977: 32906977
403BRCA2NM_000059.3(BRCA2): c.1368_1369delGA (p.Lys457Alafs)deletionPathogenicrs397507583GRCh37Chr 13, 32906983: 32906984
404BRCA2NM_000059.3(BRCA2): c.1399A> T (p.Lys467Ter)SNVPathogenicrs80358427GRCh37Chr 13, 32907014: 32907014
405BRCA2NM_000059.3(BRCA2): c.1405_1406delGA (p.Asp469Terfs)deletionPathogenicrs397507586GRCh37Chr 13, 32907020: 32907021
406BRCA2NM_000059.3(BRCA2): c.1414C> T (p.Gln472Ter)SNVPathogenicrs80358429GRCh37Chr 13, 32907029: 32907029
407BRCA2NM_000059.3(BRCA2): c.1456C> T (p.Gln486Ter)SNVPathogenicrs80358434GRCh37Chr 13, 32907071: 32907071
408BRCA2NM_000059.3(BRCA2): c.145G> T (p.Glu49Ter)SNVPathogenicrs80358435GRCh37Chr 13, 32893291: 32893291
409BRCA2NM_000059.3(BRCA2): c.1496_1497delAG (p.Gln499Argfs)deletionPathogenicrs80359285GRCh37Chr 13, 32907111: 32907112
410BRCA2NM_000059.3(BRCA2): c.1499delG (p.Gly500Valfs)deletionPathogenicrs397507591GRCh37Chr 13, 32907114: 32907114
411BRCA2NM_000059.3(BRCA2): c.1511_1512delCT (p.Ser504Tyrfs)deletionPathogenicrs80359286GRCh37Chr 13, 32907126: 32907127
412BRCA2NM_000059.3(BRCA2): c.1514delT (p.Ile505Asnfs)deletionPathogenicrs397507592GRCh37Chr 13, 32907129: 32907129
413BRCA2NM_000059.3(BRCA2): c.151delG (p.Glu51Asnfs)deletionPathogenicrs80359287GRCh37Chr 13, 32893297: 32893297
414BRCA2NM_000059.3(BRCA2): c.1528G> T (p.Glu510Ter)SNVPathogenicrs80358438GRCh37Chr 13, 32907143: 32907143
415BRCA2NM_000059.3(BRCA2): c.1540dupG (p.Glu514Glyfs)duplicationPathogenicrs397507593GRCh37Chr 13, 32907155: 32907155
416BRCA2NM_000059.3(BRCA2): c.1547delT (p.Phe516Serfs)deletionPathogenicrs80359289GRCh37Chr 13, 32907162: 32907162
417BRCA2NM_000059.3(BRCA2): c.1572delG (p.Met524Ilefs)deletionPathogenicrs397507594GRCh37Chr 13, 32907187: 32907187
418BRCA2NM_000059.3(BRCA2): c.1594G> T (p.Glu532Ter)SNVPathogenicrs138734772GRCh37Chr 13, 32907209: 32907209
419BRCA2NM_000059.3(BRCA2): c.1595_1599delAAACT (p.Glu532Glyfs)deletionPathogenicrs80359291GRCh37Chr 13, 32907210: 32907214
420BRCA2NM_000059.3(BRCA2): c.1597delA (p.Thr533Leufs)deletionPathogenicrs80359292GRCh37Chr 13, 32907212: 32907212
421BRCA2NM_000059.3(BRCA2): c.1599_1600delTG (p.Glu534Serfs)deletionPathogenicrs80359293GRCh37Chr 13, 32907214: 32907215
422BRCA2NM_000059.3(BRCA2): c.1617delA (p.Leu540Trpfs)deletionPathogenicrs80359294GRCh37Chr 13, 32907232: 32907232
423BRCA2NM_000059.3(BRCA2): c.1631_1632delCT (p.Thr544Serfs)deletionPathogenicrs80359295GRCh37Chr 13, 32907246: 32907247
424BRCA2NM_000059.3(BRCA2): c.1636delT (p.Cys546Alafs)deletionPathogenicrs397507598GRCh37Chr 13, 32907251: 32907251
425BRCA2NM_000059.3(BRCA2): c.1670T> G (p.Leu557Ter)SNVPathogenicrs80358452GRCh37Chr 13, 32907285: 32907285
426BRCA2NM_000059.3(BRCA2): c.1670_1683delTAATTGATAATGGA (p.Leu557Terfs)deletionPathogenicrs397507600GRCh37Chr 13, 32907285: 32907298
427BRCA2NM_000059.3(BRCA2): c.1672delA (p.Ile558Leufs)deletionPathogenicrs397507601GRCh37Chr 13, 32907287: 32907287
428BRCA2NM_000059.3(BRCA2): c.1681G> T (p.Gly561Ter)SNVPathogenicrs80358455GRCh37Chr 13, 32907296: 32907296
429BRCA2NM_000059.3(BRCA2): c.1689G> A (p.Trp563Ter)SNVPathogenicrs80358456GRCh37Chr 13, 32907304: 32907304
430BRCA2NM_000059.3(BRCA2): c.1705delC (p.Gln569Argfs)deletionPathogenicrs80359300GRCh37Chr 13, 32907320: 32907320
431BRCA2NM_000059.3(BRCA2): c.170dupA (p.Tyr57Terfs)duplicationPathogenicrs80359299GRCh37Chr 13, 32893316: 32893316
432BRCA2NM_000059.3(BRCA2): c.171C> G (p.Tyr57Ter)SNVPathogenicrs201523522GRCh37Chr 13, 32893317: 32893317
433BRCA2NM_000059.3(BRCA2): c.1748T> A (p.Leu583Ter)SNVPathogenicrs397507604GRCh37Chr 13, 32907363: 32907363
434BRCA2NM_000059.3(BRCA2): c.1748delT (p.Leu583Terfs)deletionPathogenicrs397507605GRCh37Chr 13, 32907363: 32907363
435BRCA2NM_000059.3(BRCA2): c.1754delA (p.Lys585Argfs)deletionPathogenicrs80359301GRCh37Chr 13, 32907369: 32907369
436BRCA2NM_000059.3(BRCA2): c.1763_1766delATAA (p.Asn588Serfs)deletionPathogenicrs80359303GRCh37Chr 13, 32907378: 32907381
437BRCA2NM_000059.3(BRCA2): c.1765_1766delAA (p.Lys589Valfs)deletionPathogenicrs397507606GRCh37Chr 13, 32907380: 32907381
438BRCA2NM_000059.3(BRCA2): c.1773_1776delTTAT (p.Ile591Metfs)deletionPathogenicrs80359304GRCh37Chr 13, 32907388: 32907391
439BRCA2NM_000059.3(BRCA2): c.1789G> T (p.Glu597Ter)SNVPathogenicrs80358461GRCh37Chr 13, 32907404: 32907404
440BRCA2NM_000059.3(BRCA2): c.1797_1801delTTATA (p.Tyr600Argfs)deletionPathogenicrs397507607GRCh37Chr 13, 32907412: 32907416
441BRCA2NM_000059.3(BRCA2): c.17_18delAA (p.Lys6Argfs)deletionPathogenicrs80359298GRCh37Chr 13, 32890614: 32890615
442BRCA2NM_000059.3(BRCA2): c.1800T> G (p.Tyr600Ter)SNVPathogenicrs80358464GRCh37Chr 13, 32907415: 32907415
443BRCA2NM_000059.3(BRCA2): c.1805delG (p.Gly602Glufs)deletionPathogenicrs397507608GRCh37Chr 13, 32907420: 32907420
444BRCA2NM_000059.3(BRCA2): c.1815dupA (p.Pro606Thrfs)duplicationPathogenicrs80359310GRCh37Chr 13, 32907430: 32907430
445BRCA2NM_000059.3(BRCA2): c.1825C> T (p.Gln609Ter)SNVPathogenicrs80358472GRCh37Chr 13, 32907440: 32907440
446BRCA2NM_000059.3(BRCA2): c.1831delT (p.Ser611Glnfs)deletionPathogenicrs80359311GRCh37Chr 13, 32907446: 32907446
447BRCA2NM_000059.3(BRCA2): c.1842dupT (p.Asn615Terfs)duplicationPathogenicrs80359312GRCh37Chr 13, 32907457: 32907457
448BRCA2NM_000059.3(BRCA2): c.1854delCinsAA (p.Gln619Thrfs)indelPathogenicrs276174815GRCh37Chr 13, 32907469: 32907469
449BRCA2NM_000059.3(BRCA2): c.1888dupA (p.Thr630Asnfs)duplicationPathogenicrs80359314GRCh37Chr 13, 32907503: 32907503
450BRCA2NM_000059.3(BRCA2): c.1899_1900insTT (p.Ala634Leufs)insertionPathogenicrs397507613GRCh37Chr 13, 32907514: 32907515
451BRCA2NM_000059.3(BRCA2): c.1933delA (p.Arg645Glufs)deletionPathogenicrs397507616GRCh37Chr 13, 32910425: 32910425
452BRCA2NM_000059.3(BRCA2): c.196C> T (p.Gln66Ter)SNVPathogenicrs397507617GRCh37Chr 13, 32893342: 32893342
453BRCA2NM_000059.3(BRCA2): c.2026delT (p.Cys676Valfs)deletionPathogenicrs80359317GRCh37Chr 13, 32910518: 32910518
454BRCA2NM_000059.3(BRCA2): c.2049_2050delTC (p.Gln684Glyfs)deletionPathogenicrs80359319GRCh37Chr 13, 32910541: 32910542
455BRCA2NM_000059.3(BRCA2): c.204delA (p.Lys68Asnfs)deletionPathogenicrs80359320GRCh37Chr 13, 32893350: 32893350
456BRCA2NM_000059.3(BRCA2): c.2064T> G (p.Tyr688Ter)SNVPathogenicrs80358485GRCh37Chr 13, 32910556: 32910556
457BRCA2NM_000059.3(BRCA2): c.2094delA (p.Gln699Serfs)deletionPathogenicrs80359323GRCh37Chr 13, 32910586: 32910586
458BRCA2NM_000059.3(BRCA2): c.2103_2106delTATT (p.Phe701Leufs)deletionPathogenicrs80359324GRCh37Chr 13, 32910595: 32910598
459BRCA2NM_000059.3(BRCA2): c.2150delG (p.Cys717Leufs)deletionPathogenicrs397507618GRCh37Chr 13, 32910642: 32910642
460BRCA2NM_000059.3(BRCA2): c.215delAinsTT (p.Asn72Ilefs)indelPathogenicrs397507619GRCh37Chr 13, 32893361: 32893361
461BRCA2NM_000059.3(BRCA2): c.2224C> T (p.Gln742Ter)SNVPathogenicrs80358494GRCh37Chr 13, 32910716: 32910716
462BRCA2NM_000059.3(BRCA2): c.2254_2257delGACT (p.Asp752Phefs)deletionPathogenicrs80359326GRCh37Chr 13, 32910746: 32910749
463BRCA2NM_000059.3(BRCA2): c.2259delT (p.Gln754Asnfs)deletionPathogenicrs397507621GRCh37Chr 13, 32910751: 32910751
464BRCA2NM_000059.3(BRCA2): c.227C> G (p.Ser76Ter)SNVPathogenicrs80358498GRCh37Chr 13, 32893373: 32893373
465BRCA2NM_000059.3(BRCA2): c.2287delC (p.His763Metfs)deletionPathogenicrs80359327GRCh37Chr 13, 32910779: 32910779
466BRCA2NM_000059.3(BRCA2): c.22_23delAG (p.Arg8Alafs)deletionPathogenicrs397507623GRCh37Chr 13, 32890619: 32890620
467BRCA2NM_000059.3(BRCA2): c.2376C> A (p.Tyr792Ter)SNVPathogenicrs80358503GRCh37Chr 13, 32910868: 32910868
468BRCA2NM_000059.3(BRCA2): c.2402_2412delACAATTATGAA (p.Asn801Ilefs)deletionPathogenicrs397507625GRCh37Chr 13, 32910894: 32910904
469BRCA2NM_000059.3(BRCA2): c.2435delA (p.Asn812Ilefs)deletionPathogenicrs80359329GRCh37Chr 13, 32910927: 32910927
470BRCA2NM_000059.3(BRCA2): c.2435dupA (p.Asn812Lysfs)duplicationPathogenicrs397507626GRCh37Chr 13, 32910927: 32910927
471BRCA2NM_000059.3(BRCA2): c.2442delC (p.Met815Trpfs)deletionPathogenicrs397507627GRCh37Chr 13, 32910934: 32910934
472BRCA2NM_000059.3(BRCA2): c.2446delG (p.Glu816Lysfs)deletionPathogenicrs80359330GRCh37Chr 13, 32910938: 32910938
473BRCA2NM_000059.3(BRCA2): c.244A> T (p.Lys82Ter)SNVPathogenicrs397507628GRCh37Chr 13, 32893390: 32893390
474BRCA2NM_000059.3(BRCA2): c.2450delA (p.Lys817Argfs)deletionPathogenicrs80359331GRCh37Chr 13, 32910942: 32910942
475BRCA2NM_000059.3(BRCA2): c.2455C> T (p.Gln819Ter)SNVPathogenicrs397507629GRCh37Chr 13, 32910947: 32910947
476BRCA2NM_000059.3(BRCA2): c.2471_2476delTAAATG (p.Leu824_Arg1160delinsTer)deletionPathogenicrs276174823GRCh37Chr 13, 32910963: 32910968
477BRCA2NM_000059.3(BRCA2): c.2517C> A (p.Tyr839Ter)SNVPathogenicrs80358516GRCh37Chr 13, 32911009: 32911009
478BRCA2NM_000059.3(BRCA2): c.2537C> G (p.Ser846Ter)SNVPathogenicrs80358518GRCh37Chr 13, 32911029: 32911029
479BRCA2NM_000059.3(BRCA2): c.2545delG (p.Val849Tyrfs)deletionPathogenicrs80359333GRCh37Chr 13, 32911037: 32911037
480BRCA2NM_000059.3(BRCA2): c.2564_2565delCA (p.Thr855Lysfs)deletionPathogenicrs80359334GRCh37Chr 13, 32911056: 32911057
481BRCA2NM_000059.3(BRCA2): c.2586_2592delAAATCAA (p.Asn863Lysfs)deletionPathogenicrs80359336GRCh37Chr 13, 32911078: 32911084
482BRCA2NM_000059.3(BRCA2): c.2589delT (p.Gln864Lysfs)deletionPathogenicrs397507632GRCh37Chr 13, 32911081: 32911081
483BRCA2NM_000059.3(BRCA2): c.2603delC (p.Thr868Ilefs)deletionPathogenicrs276174824GRCh37Chr 13, 32911095: 32911095
484BRCA2NM_000059.3(BRCA2): c.2612C> A (p.Ser871Ter)SNVPathogenicrs397507634GRCh37Chr 13, 32911104: 32911104
485BRCA2NM_000059.3(BRCA2): c.2636_2637delCT (p.Ser879Terfs)deletionPathogenicrs276174826GRCh37Chr 13, 32911128: 32911129
486BRCA2NM_000059.3(BRCA2): c.263delT (p.Leu88Argfs)deletionPathogenicrs80359339GRCh37Chr 13, 32893409: 32893409
487BRCA2NM_000059.3(BRCA2): c.2653_2656delGACA (p.Asp885Metfs)deletionPathogenicrs80359340GRCh37Chr 13, 32911145: 32911148
488BRCA2NM_000059.3(BRCA2): c.266delC (p.Pro89Argfs)deletionPathogenicrs80359341GRCh37Chr 13, 32893412: 32893412
489BRCA2NM_000059.3(BRCA2): c.2684delC (p.Ala895Valfs)deletionPathogenicrs80359342GRCh37Chr 13, 32911176: 32911176
490BRCA2NM_000059.3(BRCA2): c.2701delC (p.Ala902Leufs)deletionPathogenicrs397507637GRCh37Chr 13, 32911193: 32911193
491BRCA2NM_000059.3(BRCA2): c.2731delG (p.Glu911Lysfs)deletionPathogenicrs80359344GRCh37Chr 13, 32911223: 32911223
492BRCA2NM_000059.3(BRCA2): c.273C> A (p.Tyr91Ter)SNVPathogenicrs145988146GRCh37Chr 13, 32893419: 32893419
493BRCA2NM_000059.3(BRCA2): c.273C> G (p.Tyr91Ter)SNVPathogenicrs145988146GRCh37Chr 13, 32893419: 32893419
494BRCA2NM_000059.3(BRCA2): c.2748T> A (p.Cys916Ter)SNVPathogenicrs397507638GRCh37Chr 13, 32911240: 32911240
495BRCA2NM_000059.3(BRCA2): c.2760delC (p.Ile921Phefs)deletionPathogenicrs80359346GRCh37Chr 13, 32911252: 32911252
496BRCA2NM_000059.3(BRCA2): c.2765dupT (p.Lys923Glnfs)duplicationPathogenicrs397507639GRCh37Chr 13, 32911257: 32911257
497BRCA2NM_000059.3(BRCA2): c.276dupA (p.Ser93Ilefs)duplicationPathogenicrs80359345GRCh37Chr 13, 32893422: 32893422
498BRCA2NM_000059.3(BRCA2): c.2786delT (p.Leu929Tyrfs)deletionPathogenicrs397507642GRCh37Chr 13, 32911278: 32911278
499BRCA2NM_000059.3(BRCA2): c.2786dupT (p.Leu929Phefs)duplicationPathogenicrs80359347GRCh37Chr 13, 32911278: 32911278
500BRCA2NM_000059.3(BRCA2): c.2798_2799delCA (p.Thr933Argfs)deletionPathogenicrs80359348GRCh37Chr 13, 32911290: 32911291
501BRCA2NM_000059.3(BRCA2): c.2798delC (p.Thr933Lysfs)deletionPathogenicrs80359349GRCh37Chr 13, 32911290: 32911290
502BRCA2NM_000059.3(BRCA2): c.2805_2808delTAAA (p.Ala938Profs)deletionPathogenicrs80359350GRCh37Chr 13, 32911297: 32911300
503BRCA2NM_000059.3(BRCA2): c.2810_2811delAA (p.Gln937Argfs)deletionPathogenicrs80359353GRCh37Chr 13, 32911302: 32911303
504BRCA2NM_000059.3(BRCA2): c.2830A> T (p.Lys944Ter)SNVPathogenicrs80358533GRCh37Chr 13, 32911322: 32911322
505BRCA2NM_000059.3(BRCA2): c.2836delG (p.Asp946Ilefs)deletionPathogenicrs80359358GRCh37Chr 13, 32911328: 32911328
506BRCA2NM_000059.3(BRCA2): c.2845delT (p.Tyr949Metfs)deletionPathogenicrs397507644GRCh37Chr 13, 32911337: 32911337
507BRCA2NM_000059.3(BRCA2): c.2870delA (p.Asn957Ilefs)deletionPathogenicrs397507645GRCh37Chr 13, 32911362: 32911362
508BRCA2NM_000059.3(BRCA2): c.2881C> T (p.Gln961Ter)SNVPathogenicrs80358538GRCh37Chr 13, 32911373: 32911373
509BRCA2NM_000059.3(BRCA2): c.289G> T (p.Glu97Ter)SNVPathogenicrs397507646GRCh37Chr 13, 32893435: 32893435
510BRCA2NM_000059.3(BRCA2): c.2912T> G (p.Leu971Ter)SNVPathogenicrs397507647GRCh37Chr 13, 32911404: 32911404
511BRCA2NM_000059.3(BRCA2): c.298A> T (p.Lys100Ter)SNVPathogenicrs80358546GRCh37Chr 13, 32893444: 32893444
512BRCA2NM_000059.3(BRCA2): c.2T> C (p.Met1Thr)SNVPathogenicrs80358547GRCh37Chr 13, 32890599: 32890599
513BRCA2NM_000059.3(BRCA2): c.2T> G (p.Met1Arg)SNVPathogenicrs80358547GRCh37Chr 13, 32890599: 32890599
514BRCA2NM_000059.3(BRCA2): c.3018delA (p.Gly1007Valfs)deletionPathogenicrs397507651GRCh37Chr 13, 32911510: 32911510
515BRCA2NM_000059.3(BRCA2): c.3043A> T (p.Lys1015Ter)SNVPathogenicrs397507652GRCh37Chr 13, 32911535: 32911535
516BRCA2NM_000059.3(BRCA2): c.3051delC (p.Lys1018Serfs)deletionPathogenicrs80359367GRCh37Chr 13, 32911543: 32911543
517BRCA2NM_000059.3(BRCA2): c.3068dupA (p.Asn1023Lysfs)duplicationPathogenicrs80359368GRCh37Chr 13, 32911560: 32911560
518BRCA2NM_000059.3(BRCA2): c.306dupA (p.Leu103Ilefs)duplicationPathogenicrs397507654GRCh37Chr 13, 32893452: 32893452
519BRCA2NM_000059.3(BRCA2): c.3076A> T (p.Lys1026Ter)SNVPathogenicrs80358552GRCh37Chr 13, 32911568: 32911568
520BRCA2NM_000059.3(BRCA2): c.3146delA (p.Asn1049Ilefs)deletionPathogenicrs80359370GRCh37Chr 13, 32911638: 32911638
521BRCA2NM_000059.3(BRCA2): c.314T> G (p.Leu105Ter)SNVPathogenicrs80358561GRCh37Chr 13, 32893460: 32893460
522BRCA2NM_000059.3(BRCA2): c.316+2T> CSNVPathogenicrs81002805GRCh37Chr 13, 32893464: 32893464
523BRCA2NM_000059.3(BRCA2): c.3167_3170delAAAA (p.Gln1056Argfs)deletionPathogenicrs80359372GRCh37Chr 13, 32911659: 32911662
524BRCA2NM_000059.3(BRCA2): c.3189_3192delGTCA (p.Ser1064Leufs)deletionPathogenicrs80359374GRCh37Chr 13, 32911681: 32911684
525BRCA2NM_000059.3(BRCA2): c.3195_3198delTAAT (p.Asn1066Leufs)deletionPathogenicrs80359375GRCh37Chr 13, 32911687: 32911690
526BRCA2NM_000059.3(BRCA2): c.3195delT (p.Asn1066Ilefs)deletionPathogenicrs397507657GRCh37Chr 13, 32911687: 32911687
527BRCA2NM_000059.3(BRCA2): c.3199delA (p.Thr1067Leufs)deletionPathogenicrs80359377GRCh37Chr 13, 32911691: 32911691
528BRCA2NM_000059.3(BRCA2): c.3202delG (p.Val1068Tyrfs)deletionPathogenicrs397507658GRCh37Chr 13, 32911694: 32911694
529BRCA2NM_000059.3(BRCA2): c.3226_3230delGTAGT (p.Val1076Cysfs)deletionPathogenicrs397507659GRCh37Chr 13, 32911718: 32911722
530BRCA2NM_000059.3(BRCA2): c.3228_3229delAG (p.Val1077Cysfs)deletionPathogenicrs80359378GRCh37Chr 13, 32911720: 32911721
531BRCA2NM_000059.3(BRCA2): c.3262_3263delCC (p.Pro1088Serfs)deletionPathogenicrs80359379GRCh37Chr 13, 32911754: 32911755
532BRCA2NM_000059.3(BRCA2): c.3265C> T (p.Gln1089Ter)SNVPathogenicrs80358573GRCh37Chr 13, 32911757: 32911757
533BRCA2NM_000059.3(BRCA2): c.3267_3268delGA (p.Gln1089Hisfs)deletionPathogenicrs397507661GRCh37Chr 13, 32911759: 32911760
534BRCA2NM_000059.3(BRCA2): c.3269delT (p.Met1090Serfs)deletionPathogenicrs80359381GRCh37Chr 13, 32911761: 32911761
535BRCA2NM_000059.3(BRCA2): c.3273_3276delATTT (p.Leu1091Phefs)deletionPathogenicrs80359382GRCh37Chr 13, 32911765: 32911768
536BRCA2NM_000059.3(BRCA2): c.3277delT (p.Ser1093Profs)deletionPathogenicrs276174833GRCh37Chr 13, 32911769: 32911769
537BRCA2NM_000059.3(BRCA2): c.3283C> T (p.Gln1095Ter)SNVPathogenicrs397507662GRCh37Chr 13, 32911775: 32911775
538BRCA2NM_000059.3(BRCA2): c.3319C> T (p.Gln1107Ter)SNVPathogenicrs80358578GRCh37Chr 13, 32911811: 32911811
539BRCA2NM_000059.3(BRCA2): c.3352_3356delTTAGA (p.Leu1118Argfs)deletionPathogenicrs397507664GRCh37Chr 13, 32911844: 32911848
540BRCA2NM_000059.3(BRCA2): c.3354delA (p.Glu1119Lysfs)deletionPathogenicrs80359384GRCh37Chr 13, 32911846: 32911846
541BRCA2NM_000059.3(BRCA2): c.3362C> G (p.Ser1121Ter)SNVPathogenicrs80358579GRCh37Chr 13, 32911854: 32911854
542BRCA2NM_000059.3(BRCA2): c.3381delT (p.Phe1127Leufs)deletionPathogenicrs397507666GRCh37Chr 13, 32911873: 32911873
543BRCA2NM_000059.3(BRCA2): c.3442C> T (p.Gln1148Ter)SNVPathogenicrs397507667GRCh37Chr 13, 32911934: 32911934
544BRCA2NM_000059.3(BRCA2): c.3452dupT (p.Thr1154Aspfs)duplicationPathogenicrs397507669GRCh37Chr 13, 32911944: 32911944
545BRCA2NM_000059.3(BRCA2): c.3453delC (p.Leu1152Terfs)deletionPathogenicrs397507670GRCh37Chr 13, 32911945: 32911945
546BRCA2NM_000059.3(BRCA2): c.3455T> G (p.Leu1152Ter)SNVPathogenicrs80358593GRCh37Chr 13, 32911947: 32911947
547BRCA2NM_000059.3(BRCA2): c.3465_3466delTT (p.Ser1156Terfs)deletionPathogenicrs397507671GRCh37Chr 13, 32911957: 32911958
548BRCA2NM_000059.3(BRCA2): c.3469G> T (p.Glu1157Ter)SNVPathogenicrs80358595GRCh37Chr 13, 32911961: 32911961
549BRCA2NM_000059.3(BRCA2): c.3487delG (p.Asp1163Ilefs)deletionPathogenicrs397507672GRCh37Chr 13, 32911979: 32911979
550BRCA2NM_000059.3(BRCA2): c.3500_3501delTA (p.Ile1167Asnfs)deletionPathogenicrs80359387GRCh37Chr 13, 32911992: 32911993
551BRCA2NM_000059.3(BRCA2): c.3554_3555delCA (p.Thr1185Serfs)deletionPathogenicrs80359389GRCh37Chr 13, 32912046: 32912047
552BRCA2NM_000059.3(BRCA2): c.3570delG (p.Lys1191Serfs)deletionPathogenicrs80359390GRCh37Chr 13, 32912062: 32912062
553BRCA2NM_000059.3(BRCA2): c.3593delA (p.Asn1198Metfs)deletionPathogenicrs397507677GRCh37Chr 13, 32912085: 32912085
554BRCA2NM_000059.3(BRCA2): c.3641dupT (p.Phe1216Valfs)duplicationPathogenicrs397507678GRCh37Chr 13, 32912133: 32912133
555BRCA2NM_000059.3(BRCA2): c.3645_3646delGTinsTAAAAAG (p.Phe1216Lysfs)indelPathogenicrs397507679GRCh37Chr 13, 32912137: 32912138
556BRCA2NM_000059.3(BRCA2): c.3682_3685delAATG (p.Asn1228Phefs)deletionPathogenicrs80359396GRCh37Chr 13, 32912174: 32912177
557BRCA2NM_000059.3(BRCA2): c.3685delG (p.Val1229Phefs)deletionPathogenicrs80359397GRCh37Chr 13, 32912177: 32912177
558BRCA2NM_000059.3(BRCA2): c.36delT (p.Phe12Leufs)deletionPathogenicrs80359399GRCh37Chr 13, 32890633: 32890633
559BRCA2NM_000059.3(BRCA2): c.36dupT (p.Glu13Terfs)duplicationPathogenicrs80359393GRCh37Chr 13, 32890633: 32890633
560BRCA2NM_000059.3(BRCA2): c.370delA (p.Met124Trpfs)deletionPathogenicrs397507681GRCh37Chr 13, 32899266: 32899266
561BRCA2NM_000059.3(BRCA2): c.3723_3725delTAGinsAT (p.Phe1241Leufs)indelPathogenicrs397507682GRCh37Chr 13, 32912215: 32912217
562BRCA2NM_000059.3(BRCA2): c.3737delA (p.Asn1246Ilefs)deletionPathogenicrs80359402GRCh37Chr 13, 32912229: 32912229
563BRCA2NM_000059.3(BRCA2): c.3748G> T (p.Glu1250Ter)SNVPathogenicrs80358615GRCh37Chr 13, 32912240: 32912240
564BRCA2NM_000059.3(BRCA2): c.3751dupA (p.Thr1251Asnfs)duplicationPathogenicrs397507683GRCh37Chr 13, 32912243: 32912243
565BRCA2NM_000059.3(BRCA2): c.3772delA (p.Ile1258Terfs)deletionPathogenicrs397507684GRCh37Chr 13, 32912264: 32912264
566BRCA2NM_000059.3(BRCA2): c.3778_3779delTT (p.Leu1260Ilefs)deletionPathogenicrs397507686GRCh37Chr 13, 32912270: 32912271
567BRCA2NM_000059.3(BRCA2): c.3785C> G (p.Ser1262Ter)SNVPathogenicrs80358620GRCh37Chr 13, 32912277: 32912277
568BRCA2NM_000059.3(BRCA2): c.37G> T (p.Glu13Ter)SNVPathogenicrs80358622GRCh37Chr 13, 32890634: 32890634
569BRCA2NM_000059.3(BRCA2): c.37_44delGAAATTTT (p.Glu13Terfs)deletionPathogenicrs397507687GRCh37Chr 13, 32890634: 32890641
570BRCA2NM_000059.3(BRCA2): c.3812C> A (p.Ser1271Ter)SNVPathogenicrs80358623GRCh37Chr 13, 32912304: 32912304
571BRCA2NM_000059.3(BRCA2): c.3824_3827delTAGA (p.Ile1275Lysfs)deletionPathogenicrs397507688GRCh37Chr 13, 32912316: 32912319
572BRCA2NM_000059.3(BRCA2): c.3837delT (p.Asn1279Lysfs)deletionPathogenicrs80359404GRCh37Chr 13, 32912329: 32912329
573BRCA2NM_000059.3(BRCA2): c.3847delG (p.Val1283Terfs)deletionPathogenicrs397507691GRCh37Chr 13, 32912339: 32912339
574BRCA2NM_000059.3(BRCA2): c.3849_3852delAAGT (p.Ser1284Lysfs)deletionPathogenicrs397507692GRCh37Chr 13, 32912341: 32912344
575BRCA2NM_000059.3(BRCA2): c.3859_3860delAA (p.Asn1287Terfs)deletionPathogenicrs80359408GRCh37Chr 13, 32912351: 32912352
576BRCA2NM_000059.3(BRCA2): c.3860_3863delATAA (p.Asn1287Ilefs)deletionPathogenicrs80359410GRCh37Chr 13, 32912352: 32912355
577BRCA2NM_000059.3(BRCA2): c.3860delA (p.Asn1287Ilefs)deletionPathogenicrs80359406GRCh37Chr 13, 32912352: 32912352
578BRCA2NM_000059.3(BRCA2): c.3860dupA (p.Asn1287Lysfs)duplicationPathogenicrs80359409GRCh37Chr 13, 32912352: 32912352
579BRCA2NM_000059.3(BRCA2): c.3866_3867delAA (p.Lys1289Metfs)deletionPathogenicrs397507694GRCh37Chr 13, 32912358: 32912359
580BRCA2NM_000059.3(BRCA2): c.3871C> T (p.Gln1291Ter)SNVPathogenicrs80358631GRCh37Chr 13, 32912363: 32912363
581BRCA2NM_000059.3(BRCA2): c.3881T> A (p.Leu1294Ter)SNVPathogenicrs80358632GRCh37Chr 13, 32912373: 32912373
582BRCA2NM_000059.3(BRCA2): c.3887delA (p.Asn1296Ilefs)deletionPathogenicrs397507695GRCh37Chr 13, 32912379: 32912379
583BRCA2NM_000059.3(BRCA2): c.3911delC (p.Thr1304Ilefs)deletionPathogenicrs80359415GRCh37Chr 13, 32912403: 32912403
584BRCA2NM_000059.3(BRCA2): c.3915delT (p.Phe1305Leufs)deletionPathogenicrs397507698GRCh37Chr 13, 32912407: 32912407
585BRCA2NM_000059.3(BRCA2): c.3919delG (p.Glu1307Lysfs)deletionPathogenicrs80359416GRCh37Chr 13, 32912411: 32912411
586BRCA2NM_000059.3(BRCA2): c.3936_3954del19 (p.Asn1312Lysfs)deletionPathogenicrs397507700GRCh37Chr 13, 32912428: 32912446
587BRCA2NM_000059.3(BRCA2): c.3939C> A (p.Tyr1313Ter)SNVPathogenicrs80358641GRCh37Chr 13, 32912431: 32912431
588BRCA2NM_000059.3(BRCA2): c.3939delC (p.Tyr1313Terfs)deletionPathogenicrs276174838GRCh37Chr 13, 32912431: 32912431
589BRCA2NM_000059.3(BRCA2): c.3958G> T (p.Glu1320Ter)SNVPathogenicrs80358644GRCh37Chr 13, 32912450: 32912450
590BRCA2NM_000059.3(BRCA2): c.3967A> T (p.Lys1323Ter)SNVPathogenicrs80358648GRCh37Chr 13, 32912459: 32912459
591BRCA2NM_000059.3(BRCA2): c.3975_3978dupTGCT (p.Ala1327Cysfs)duplicationPathogenicrs397515636GRCh37Chr 13, 32912467: 32912470
592BRCA2NM_000059.3(BRCA2): c.3G> A (p.Met1Ile)SNVPathogenicrs80358650GRCh37Chr 13, 32890600: 32890600
593BRCA2NM_000059.3(BRCA2): c.4001T> A (p.Leu1334Ter)SNVPathogenicrs80358652GRCh37Chr 13, 32912493: 32912493
594BRCA2NM_000059.3(BRCA2): c.4005dupA (p.Phe1336Ilefs)duplicationPathogenicrs397507701GRCh37Chr 13, 32912497: 32912497
595BRCA2NM_000059.3(BRCA2): c.4021delT (p.Ser1341Glnfs)deletionPathogenicrs397507702GRCh37Chr 13, 32912513: 32912513
596BRCA2NM_000059.3(BRCA2): c.4037_4038delCT (p.Thr1346Serfs)deletionPathogenicrs80359421GRCh37Chr 13, 32912529: 32912530
597BRCA2NM_000059.3(BRCA2): c.4048_4051delCATA (p.His1350Lysfs)deletionPathogenicrs80359423GRCh37Chr 13, 32912540: 32912543
598BRCA2NM_000059.3(BRCA2): c.4076delC (p.Thr1359Metfs)deletionPathogenicrs80359424GRCh37Chr 13, 32912568: 32912568
599BRCA2NM_000059.3(BRCA2): c.4095T> A (p.Cys1365Ter)SNVPathogenicrs80358658GRCh37Chr 13, 32912587: 32912587
600BRCA2NM_000059.3(BRCA2): c.4095delT (p.Lys1367Asnfs)deletionPathogenicrs397507703GRCh37Chr 13, 32912587: 32912587
601BRCA2NM_000059.3(BRCA2): c.4101delA (p.Lys1367Asnfs)deletionPathogenicrs397507705GRCh37Chr 13, 32912593: 32912593
602BRCA2NM_000059.3(BRCA2): c.410delC (p.Ser137Phefs)deletionPathogenicrs80359427GRCh37Chr 13, 32899306: 32899306
603BRCA2NM_000059.3(BRCA2): c.4111C> T (p.Gln1371Ter)SNVPathogenicrs80358659GRCh37Chr 13, 32912603: 32912603
604BRCA2NM_000059.3(BRCA2): c.4121delA (p.Lys1374Argfs)deletionPathogenicrs397507707GRCh37Chr 13, 32912613: 32912613
605BRCA2NM_000059.3(BRCA2): c.4130delA (p.Asn1377Thrfs)deletionPathogenicrs80359428GRCh37Chr 13, 32912622: 32912622
606BRCA2NM_000059.3(BRCA2): c.4137_4141delGATTA (p.Ile1380Argfs)deletionPathogenicrs80359431GRCh37Chr 13, 32912629: 32912633
607BRCA2NM_000059.3(BRCA2): c.4139_4140dupTT (p.Lys1381Leufs)duplicationPathogenicrs276174842GRCh37Chr 13, 32912631: 32912632
608BRCA2NM_000059.3(BRCA2): c.4151delT (p.Leu1384Cysfs)deletionPathogenicrs397507710GRCh37Chr 13, 32912643: 32912643
609BRCA2NM_000059.3(BRCA2): c.4169delT (p.Leu1390Trpfs)deletionPathogenicrs80359433GRCh37Chr 13, 32912661: 32912661
610BRCA2NM_000059.3(BRCA2): c.4171delG (p.Glu1391Lysfs)deletionPathogenicrs397507711GRCh37Chr 13, 32912663: 32912663
611BRCA2NM_000059.3(BRCA2): c.4188delA (p.Glu1397Lysfs)deletionPathogenicrs80359434GRCh37Chr 13, 32912680: 32912680
612BRCA2NM_000059.3(BRCA2): c.4218_4221delAGAA (p.Lys1406Asnfs)deletionPathogenicrs80359435GRCh37Chr 13, 32912710: 32912713
613BRCA2NM_000059.3(BRCA2): c.4223delA (p.Gln1408Argfs)deletionPathogenicrs397507712GRCh37Chr 13, 32912715: 32912715
614BRCA2NM_000059.3(BRCA2): c.4258delG (p.Asp1420Ilefs)deletionPathogenicrs80359436GRCh37Chr 13, 32912750: 32912750
615BRCA2NM_000059.3(BRCA2): c.4271delC (p.Ser1424Leufs)deletionPathogenicrs80359437GRCh37Chr 13, 32912763: 32912763
616BRCA2NM_000059.3(BRCA2): c.4285C> T (p.Gln1429Ter)SNVPathogenicrs80358665GRCh37Chr 13, 32912777: 32912777
617BRCA2NM_000059.3(BRCA2): c.4314delC (p.Ala1439Profs)deletionPathogenicrs80359441GRCh37Chr 13, 32912806: 32912806
618BRCA2NM_000059.3(BRCA2): c.4325C> A (p.Ser1442Ter)SNVPathogenicrs80358670GRCh37Chr 13, 32912817: 32912817
619BRCA2NM_000059.3(BRCA2): c.4339delG (p.Val1447Terfs)deletionPathogenicrs80359443GRCh37Chr 13, 32912831: 32912831
620BRCA2NM_000059.3(BRCA2): c.4380_4381delTT (p.Ser1461Leufs)deletionPathogenicrs397507715GRCh37Chr 13, 32912872: 32912873
621BRCA2NM_000059.3(BRCA2): c.438delA (p.Gln147Asnfs)deletionPathogenicrs397507716GRCh37Chr 13, 32900250: 32900250
622BRCA2NM_000059.3(BRCA2): c.439C> T (p.Gln147Ter)SNVPathogenicrs397507717GRCh37Chr 13, 32900251: 32900251
623BRCA2NM_000059.3(BRCA2): c.4409_4410delTA (p.Ile1470Lysfs)deletionPathogenicrs80359446GRCh37Chr 13, 32912901: 32912902
624BRCA2NM_000059.3(BRCA2): c.4409_4413delTAAGA (p.Ile1470Lysfs)deletionPathogenicrs397507718GRCh37Chr 13, 32912901: 32912905
625BRCA2NM_000059.3(BRCA2): c.4423delA (p.Met1475Trpfs)deletionPathogenicrs80359447GRCh37Chr 13, 32912915: 32912915
626BRCA2NM_000059.3(BRCA2): c.4440T> G (p.Tyr1480Ter)SNVPathogenicrs397507719GRCh37Chr 13, 32912932: 32912932
627BRCA2NM_000059.3(BRCA2): c.4456_4459delGTTA (p.Val1486Asnfs)deletionPathogenicrs80359449GRCh37Chr 13, 32912948: 32912951
628BRCA2NM_000059.3(BRCA2): c.4464_4465delCA (p.His1488Glnfs)deletionPathogenicrs397507720GRCh37Chr 13, 32912956: 32912957
629BRCA2NM_000059.3(BRCA2): c.4480dupA (p.Ser1494Lysfs)duplicationPathogenicrs80359453GRCh37Chr 13, 32912972: 32912972
630BRCA2NM_000059.3(BRCA2): c.4525C> T (p.Gln1509Ter)SNVPathogenicrs80358683GRCh37Chr 13, 32913017: 32913017
631BRCA2NM_000059.3(BRCA2): c.4535delG (p.Arg1512Leufs)deletionPathogenicrs397507723GRCh37Chr 13, 32913027: 32913027
632BRCA2NM_000059.3(BRCA2): c.4546dupA (p.Ile1516Asnfs)duplicationPathogenicrs80359456GRCh37Chr 13, 32913038: 32913038
633BRCA2NM_000059.3(BRCA2): c.4551_4554delAGAA (p.Lys1517Asnfs)deletionPathogenicrs80359457GRCh37Chr 13, 32913043: 32913046
634BRCA2NM_000059.3(BRCA2): c.4552G> T (p.Glu1518Ter)SNVPathogenicrs397507727GRCh37Chr 13, 32913044: 32913044
635BRCA2NM_000059.3(BRCA2): c.4554delA (p.Glu1518Aspfs)deletionPathogenicrs80359458GRCh37Chr 13, 32913046: 32913046
636BRCA2NM_000059.3(BRCA2): c.4556delC (p.Pro1519Leufs)deletionPathogenicrs397507728GRCh37Chr 13, 32913048: 32913048
637BRCA2NM_000059.3(BRCA2): c.4588A> T (p.Lys1530Ter)SNVPathogenicrs80358692GRCh37Chr 13, 32913080: 32913080
638BRCA2NM_000059.3(BRCA2): c.4593dupA (p.Val1532Serfs)duplicationPathogenicrs397507732GRCh37Chr 13, 32913085: 32913085
639BRCA2NM_000059.3(BRCA2): c.462_463delAA (p.Asp156Terfs)deletionPathogenicrs80359459GRCh37Chr 13, 32900274: 32900275
640BRCA2NM_000059.3(BRCA2): c.4647_4650delAGAG (p.Lys1549Asnfs)deletionPathogenicrs397507734GRCh37Chr 13, 32913139: 32913142
641BRCA2NM_000059.3(BRCA2): c.469_470delAA (p.Lys157Valfs)deletionPathogenicrs397507739GRCh37Chr 13, 32900281: 32900282
642BRCA2NM_000059.3(BRCA2): c.470_474delAGTCA (p.Lys157Serfs)deletionPathogenicrs80359463GRCh37Chr 13, 32900282: 32900286
643BRCA2NM_000059.3(BRCA2): c.4731_4736delATTAGCinsG (p.Leu1578Metfs)indelPathogenicrs276174846GRCh37Chr 13, 32913223: 32913228
644BRCA2NM_000059.3(BRCA2): c.4742_4743insTG (p.Glu1581Aspfs)insertionPathogenicrs276174847GRCh37Chr 13, 32913234: 32913235
645BRCA2NM_000059.3(BRCA2): c.475+1G> ASNVPathogenicrs81002797GRCh37Chr 13, 32900288: 32900288
646BRCA2NM_000059.3(BRCA2): c.475+3A> GSNVPathogenicrs81002795GRCh37Chr 13, 32900290: 32900290
647BRCA2NM_000059.3(BRCA2): c.475G> A (p.Val159Met)SNVLikely pathogenic, Pathogenicrs80358702GRCh37Chr 13, 32900287: 32900287
648BRCA2NM_000059.3(BRCA2): c.4766delC (p.Pro1589Glnfs)deletionPathogenicrs397507741GRCh37Chr 13, 32913258: 32913258
649BRCA2NM_000059.3(BRCA2): c.4780delA (p.Met1594Cysfs)deletionPathogenicrs397507742GRCh37Chr 13, 32913272: 32913272
650BRCA2NM_000059.3(BRCA2): c.4797delT (p.Asn1599Lysfs)deletionPathogenicrs80359465GRCh37Chr 13, 32913289: 32913289
651BRCA2NM_000059.3(BRCA2): c.4808delA (p.Asn1603Thrfs)deletionPathogenicrs397507743GRCh37Chr 13, 32913300: 32913300
652BRCA2NM_000059.3(BRCA2): c.4808dupA (p.Asn1603Lysfs)duplicationPathogenicrs80359466GRCh37Chr 13, 32913300: 32913300
653BRCA2NM_000059.3(BRCA2): c.4828dupG (p.Val1610Glyfs)duplicationPathogenicrs397507744GRCh37Chr 13, 32913320: 32913320
654BRCA2NM_000059.3(BRCA2): c.4845_4846delCT (p.Leu1616Lysfs)deletionPathogenicrs80359469GRCh37Chr 13, 32913337: 32913338
655BRCA2NM_000059.3(BRCA2): c.4859T> G (p.Leu1620Ter)SNVPathogenicrs80358710GRCh37Chr 13, 32913351: 32913351
656BRCA2NM_000059.3(BRCA2): c.4889C> A (p.Ser1630Ter)SNVPathogenicrs80358711GRCh37Chr 13, 32913381: 32913381
657BRCA2NM_000059.3(BRCA2): c.4894_4895delAG (p.Ser1632Tyrfs)deletionPathogenicrs397507748GRCh37Chr 13, 32913386: 32913387
658BRCA2NM_000059.3(BRCA2): c.491T> A (p.Leu164Ter)SNVPathogenicrs80358717GRCh37Chr 13, 32900394: 32900394
659BRCA2NM_000059.3(BRCA2): c.4933A> T (p.Lys1645Ter)SNVPathogenicrs80358719GRCh37Chr 13, 32913425: 32913425
660BRCA2NM_000059.3(BRCA2): c.4935delA (p.Glu1646Lysfs)deletionPathogenicrs80359472GRCh37Chr 13, 32913427: 32913427
661BRCA2NM_000059.3(BRCA2): c.4940_4941delCA (p.Thr1647Serfs)deletionPathogenicrs397507751GRCh37Chr 13, 32913432: 32913433
662BRCA2NM_000059.3(BRCA2): c.4952delC (p.Pro1651Leufs)deletionPathogenicrs397507752GRCh37Chr 13, 32913444: 32913444
663BRCA2NM_000059.3(BRCA2): c.4965C> A (p.Tyr1655Ter)SNVPathogenicrs80358721GRCh37Chr 13, 32913457: 32913457
664BRCA2NM_000059.3(BRCA2): c.4987_4990delGTCA (p.Val1663Leufs)deletionPathogenicrs397507753GRCh37Chr 13, 32913479: 32913482
665BRCA2NM_000059.3(BRCA2): c.5065_5066delGCinsAAA (p.Ala1689Lysfs)indelPathogenicrs276174852GRCh37Chr 13, 32913557: 32913558
666BRCA2NM_000059.3(BRCA2): c.5073delA (p.Lys1691Asnfs)deletionPathogenicrs80359481GRCh37Chr 13, 32913565: 32913565
667BRCA2NM_000059.3(BRCA2): c.5086_5087insA (p.Gly1696Glufs)insertionPathogenicrs397507757GRCh37Chr 13, 32913578: 32913579
668BRCA2NM_000059.3(BRCA2): c.5101C> T (p.Gln1701Ter)SNVPathogenicrs397507758GRCh37Chr 13, 32913593: 32913593
669BRCA2NM_000059.3(BRCA2): c.5107G> T (p.Glu1703Ter)SNVPathogenicrs80358735GRCh37Chr 13, 32913599: 32913599
670BRCA2NM_000059.3(BRCA2): c.5116_5119delAATA (p.Asn1706Leufs)deletionPathogenicrs276174853GRCh37Chr 13, 32913608: 32913611
671BRCA2NM_000059.3(BRCA2): c.5130_5133delTGTA (p.Tyr1710Terfs)deletionPathogenicrs80359484GRCh37Chr 13, 32913622: 32913625
672BRCA2NM_000059.3(BRCA2): c.5141_5144delATTT (p.Tyr1714Cysfs)deletionPathogenicrs80359487GRCh37Chr 13, 32913633: 32913636
673BRCA2NM_000059.3(BRCA2): c.5146_5149delTATG (p.Tyr1716Lysfs)deletionPathogenicrs276174854GRCh37Chr 13, 32913638: 32913641
674BRCA2NM_000059.3(BRCA2): c.5157_5161delTTCAA (p.Asn1719Lysfs)deletionPathogenicrs80359488GRCh37Chr 13, 32913649: 32913653
675BRCA2NM_000059.3(BRCA2): c.5159C> G (p.Ser1720Ter)SNVPathogenicrs80358740GRCh37Chr 13, 32913651: 32913651
676BRCA2NM_000059.3(BRCA2): c.516+1G> ASNVPathogenicrs397507762GRCh37Chr 13, 32900420: 32900420
677BRCA2NM_000059.3(BRCA2): c.516+1G> CSNVPathogenicrs397507762GRCh37Chr 13, 32900420: 32900420
678BRCA2NM_000059.3(BRCA2): c.516+2T> ASNVPathogenicrs397507764GRCh37Chr 13, 32900421: 32900421
679BRCA2NM_000059.3(BRCA2): c.5164_5165delAG (p.Ser1722Tyrfs)deletionPathogenicrs80359490GRCh37Chr 13, 32913656: 32913657
680BRCA2NM_000059.3(BRCA2): c.516_516+1insCinsertionPathogenicrs397507766GRCh37Chr 13, 32900419: 32900420
681BRCA2NM_000059.3(BRCA2): c.517-1G> ASNVPathogenicrs81002849GRCh37Chr 13, 32900635: 32900635
682BRCA2NM_000059.3(BRCA2): c.517-2A> GSNVLikely pathogenic, Pathogenicrs81002858GRCh37Chr 13, 32900634: 32900634
683BRCA2NM_000059.3(BRCA2): c.5180delA (p.Asn1727Metfs)deletionPathogenicrs80359491GRCh37Chr 13, 32913672: 32913672
684BRCA2NM_000059.3(BRCA2): c.5180dupA (p.Asn1727Lysfs)duplicationPathogenicrs397507769GRCh37Chr 13, 32913672: 32913672
685BRCA2NM_000059.3(BRCA2): c.5197dupT (p.Ser1733Phefs)duplicationPathogenicrs397507771GRCh37Chr 13, 32913689: 32913689
686BRCA2NM_000059.3(BRCA2): c.51_52delAC (p.Arg18Leufs)deletionPathogenicrs80359483GRCh37Chr 13, 32890648: 32890649
687BRCA2NM_000059.3(BRCA2): c.51dupA (p.Arg18Thrfs)duplicationPathogenicrs397507772GRCh37Chr 13, 32890648: 32890648
688BRCA2NM_000059.3(BRCA2): c.5207_5208delAA (p.Gln1736Argfs)deletionPathogenicrs397507773GRCh37Chr 13, 32913699: 32913700
689BRCA2NM_000059.3(BRCA2): c.5208delA (p.Asp1737Ilefs)deletionPathogenicrs397507774GRCh37Chr 13, 32913700: 32913700
690BRCA2NM_000059.3(BRCA2): c.5217T> A (p.Tyr1739Ter)SNVPathogenicrs80358746GRCh37Chr 13, 32913709: 32913709
691BRCA2NM_000059.3(BRCA2): c.5217_5220delTTTA (p.Tyr1739Terfs)deletionPathogenicrs80359494GRCh37Chr 13, 32913709: 32913712
692BRCA2NM_000059.3(BRCA2): c.5217_5221delTTTAA (p.Tyr1739Terfs)deletionPathogenicrs80359495GRCh37Chr 13, 32913709: 32913713
693BRCA2NM_000059.3(BRCA2): c.5217_5223delTTTAAGT (p.Tyr1739Terfs)deletionPathogenicrs80359496GRCh37Chr 13, 32913709: 32913715
694BRCA2NM_000059.3(BRCA2): c.5217_5224delTTTAAGTA (p.Tyr1739Terfs)deletionPathogenicrs80359497GRCh37Chr 13, 32913709: 32913716
695BRCA2NM_000059.3(BRCA2): c.5254delC (p.His1752Ilefs)deletionPathogenicrs397507777GRCh37Chr 13, 32913746: 32913746
696BRCA2NM_000059.3(BRCA2): c.5286T> A (p.Tyr1762Ter)SNVPathogenicrs80358754GRCh37Chr 13, 32913778: 32913778
697BRCA2NM_000059.3(BRCA2): c.5344C> T (p.Gln1782Ter)SNVPathogenicrs80358757GRCh37Chr 13, 32913836: 32913836
698BRCA2NM_000059.3(BRCA2): c.5344_5345delCA (p.Gln1782Lysfs)deletionPathogenicrs80359506GRCh37Chr 13, 32913836: 32913837
699BRCA2NM_000059.3(BRCA2): c.5350_5351delAAinsT (p.Asn1784Serfs)indelPathogenicrs397507779GRCh37Chr 13, 32913842: 32913843
700BRCA2NM_000059.3(BRCA2): c.5353_5354delAC (p.Thr1785Terfs)deletionPathogenicrs397507780GRCh37Chr 13, 32913845: 32913846
701BRCA2NM_000059.3(BRCA2): c.5355dupT (p.Ser1786Terfs)duplicationPathogenicrs397507781GRCh37Chr 13, 32913847: 32913847
702BRCA2NM_000059.3(BRCA2): c.5380delG (p.Val1794Terfs)deletionPathogenicrs397507782GRCh37Chr 13, 32913872: 32913872
703BRCA2NM_000059.3(BRCA2): c.538_539delAT (p.Ile180Phefs)deletionPathogenicrs80359510GRCh37Chr 13, 32900657: 32900658
704BRCA2NM_000059.3(BRCA2): c.538_539dupAT (p.Ser181Phefs)duplicationPathogenicrs80359511GRCh37Chr 13, 32900657: 32900658
705BRCA2NM_000059.3(BRCA2): c.5404C> T (p.Gln1802Ter)SNVPathogenicrs80358763GRCh37Chr 13, 32913896: 32913896
706BRCA2NM_000059.3(BRCA2): c.5434G> T (p.Glu1812Ter)SNVPathogenicrs80358767GRCh37Chr 13, 32913926: 32913926
707BRCA2NM_000059.3(BRCA2): c.5439delT (p.Val1814Terfs)deletionPathogenicrs397507785GRCh37Chr 13, 32913931: 32913931
708BRCA2NM_000059.3(BRCA2): c.5454delA (p.Cys1820Alafs)deletionPathogenicrs80359513GRCh37Chr 13, 32913946: 32913946
709BRCA2NM_000059.3(BRCA2): c.5466dupT (p.Lys1823Terfs)duplicationPathogenicrs80359514GRCh37Chr 13, 32913958: 32913958
710BRCA2NM_000059.3(BRCA2): c.5471delA (p.Asn1824Metfs)deletionPathogenicrs397507786GRCh37Chr 13, 32913963: 32913963
711BRCA2NM_000059.3(BRCA2): c.5526delT (p.Ala1843Hisfs)deletionPathogenicrs80359518GRCh37Chr 13, 32914018: 32914018
712BRCA2NM_000059.3(BRCA2): c.5542delA (p.Ser1848Valfs)deletionPathogenicrs80359519GRCh37Chr 13, 32914034: 32914034
713BRCA2NM_000059.3(BRCA2): c.5560_5561delGT (p.Val1854Phefs)deletionPathogenicrs397507787GRCh37Chr 13, 32914052: 32914053
714BRCA2NM_000059.3(BRCA2): c.5569G> T (p.Glu1857Ter)SNVPathogenicrs80358778GRCh37Chr 13, 32914061: 32914061
715BRCA2NM_000059.3(BRCA2): c.5569_5573delGAAAC (p.Glu1857Asnfs)deletionPathogenicrs397507788GRCh37Chr 13, 32914061: 32914065
716BRCA2NM_000059.3(BRCA2): c.5577_5580delTAAA (p.Lys1861Terfs)deletionPathogenicrs80359522GRCh37Chr 13, 32914069: 32914072
717BRCA2NM_000059.3(BRCA2): c.5583dupA (p.Val1862Serfs)duplicationPathogenicrs397507790GRCh37Chr 13, 32914075: 32914075
718BRCA2NM_000059.3(BRCA2): c.5585_5588delTGAA (p.Val1862Glufs)deletionPathogenicrs80359523GRCh37Chr 13, 32914077: 32914080
719BRCA2NM_000059.3(BRCA2): c.5592_5593delCA (p.Phe1866Tyrfs)deletionPathogenicrs397507791GRCh37Chr 13, 32914084: 32914085
720BRCA2NM_000059.3(BRCA2): c.5624delA (p.Lys1875Argfs)deletionPathogenicrs397507792GRCh37Chr 13, 32914116: 32914116
721BRCA2NM_000059.3(BRCA2): c.5626G> T (p.Glu1876Ter)SNVPathogenicrs397507793GRCh37Chr 13, 32914118: 32914118
722BRCA2NM_000059.3(BRCA2): c.5641_5644delAAAT (p.Lys1881Glnfs)deletionPathogenicrs276174860GRCh37Chr 13, 32914133: 32914136
723BRCA2NM_000059.3(BRCA2): c.5665delA (p.Ile1889Leufs)deletionPathogenicrs397507796GRCh37Chr 13, 32914157: 32914157
724BRCA2NM_000059.3(BRCA2): c.5699C> A (p.Ser1900Ter)SNVPathogenicrs397507797GRCh37Chr 13, 32914191: 32914191
725BRCA2NM_000059.3(BRCA2): c.5702_5703delAG (p.Glu1901Glyfs)deletionPathogenicrs80359528GRCh37Chr 13, 32914194: 32914195
726BRCA2NM_000059.3(BRCA2): c.5717_5718delAC (p.Asn1906Ilefs)deletionPathogenicrs80359529GRCh37Chr 13, 32914209: 32914210
727BRCA2NM_000059.3(BRCA2): c.5724delA (p.Asp1909Ilefs)deletionPathogenicrs80359532GRCh37Chr 13, 32914216: 32914216
728BRCA2NM_000059.3(BRCA2): c.572delAinsCT (p.Asp191Alafs)indelPathogenicrs397507799GRCh37Chr 13, 32900691: 32900691
729BRCA2NM_000059.3(BRCA2): c.5734G> T (p.Glu1912Ter)SNVPathogenicrs397507800GRCh37Chr 13, 32914226: 32914226
730BRCA2NM_000059.3(BRCA2): c.5739T> A (p.Cys1913Ter)SNVPathogenicrs397507801GRCh37Chr 13, 32914231: 32914231
731BRCA2NM_000059.3(BRCA2): c.574dupA (p.Met192Asnfs)duplicationPathogenicrs397507802GRCh37Chr 13, 32900693: 32900693
732BRCA2NM_000059.3(BRCA2): c.5754_5755delTA (p.His1918Glnfs)deletionPathogenicrs397507803GRCh37Chr 13, 32914246: 32914247
733BRCA2NM_000059.3(BRCA2): c.5763dupT (p.Ala1922Cysfs)duplicationPathogenicrs80359534GRCh37Chr 13, 32914255: 32914255
734BRCA2NM_000059.3(BRCA2): c.5771_5774delTTCA (p.Ile1924Argfs)deletionPathogenicrs80359535GRCh37Chr 13, 32914263: 32914266
735BRCA2NM_000059.3(BRCA2): c.5773C> T (p.Gln1925Ter)SNVPathogenicrs80358806GRCh37Chr 13, 32914265: 32914265
736BRCA2NM_000059.3(BRCA2): c.5778_5779delTG (p.Ser1926Argfs)deletionPathogenicrs80359536GRCh37Chr 13, 32914270: 32914271
737BRCA2NM_000059.3(BRCA2): c.5789T> A (p.Leu1930Ter)SNVPathogenicrs397507805GRCh37Chr 13, 32914281: 32914281
738BRCA2NM_000059.3(BRCA2): c.5789delT (p.Leu1930Tyrfs)deletionPathogenicrs397507806GRCh37Chr 13, 32914281: 32914281
739BRCA2NM_000059.3(BRCA2): c.5791C> T (p.Gln1931Ter)SNVPathogenicrs80358807GRCh37Chr 13, 32914283: 32914283
740BRCA2NM_000059.3(BRCA2): c.5796_5797delTA (p.His1932Glnfs)deletionPathogenicrs80359537GRCh37Chr 13, 32914288: 32914289
741BRCA2NM_000059.3(BRCA2): c.5820_5833delGAAAGTTTCTAAAA (p.Glu1940Aspfs)deletionPathogenicrs80359539GRCh37Chr 13, 32914312: 32914325
742BRCA2NM_000059.3(BRCA2): c.5823delA (p.Val1942Phefs)deletionPathogenicrs80359540GRCh37Chr 13, 32914315: 32914315
743BRCA2NM_000059.3(BRCA2): c.5836_5837insA (p.Ser1946Tyrfs)insertionPathogenicrs80359542GRCh37Chr 13, 32914328: 32914329
744BRCA2NM_000059.3(BRCA2): c.5857delG (p.Glu1953Lysfs)deletionPathogenicrs80359545GRCh37Chr 13, 32914349: 32914349
745BRCA2NM_000059.3(BRCA2): c.5864C> G (p.Ser1955Ter)SNVPathogenicrs80358815GRCh37Chr 13, 32914356: 32914356
746BRCA2NM_000059.3(BRCA2): c.5898delT (p.His1966Glnfs)deletionPathogenicrs397507811GRCh37Chr 13, 32914390: 32914390
747BRCA2NM_000059.3(BRCA2): c.5904_5907delAGTC (p.Val1969Hisfs)deletionPathogenicrs80359547GRCh37Chr 13, 32914396: 32914399
748BRCA2NM_000059.3(BRCA2): c.5925T> A (p.Cys1975Ter)SNVPathogenicrs80358825GRCh37Chr 13, 32914417: 32914417
749BRCA2NM_000059.3(BRCA2): c.5945dupG (p.Ser1982Argfs)duplicationPathogenicrs397507812GRCh37Chr 13, 32914437: 32914437
750BRCA2NM_000059.3(BRCA2): c.5946_5949delTGGA (p.Ser1982Argfs)deletionPathogenicrs80359549GRCh37Chr 13, 32914438: 32914441
751BRCA2NM_000059.3(BRCA2): c.5952dupA (p.Ser1985Ilefs)duplicationPathogenicrs397507814GRCh37Chr 13, 32914444: 32914444
752BRCA2NM_000059.3(BRCA2): c.5954_5955delCT (p.Ser1985Cysfs)deletionPathogenicrs80359551GRCh37Chr 13, 32914446: 32914447
753BRCA2NM_000059.3(BRCA2): c.5959C> T (p.Gln1987Ter)SNVPathogenicrs80358828GRCh37Chr 13, 32914451: 32914451
754BRCA2NM_000059.3(BRCA2): c.5967dupA (p.Asp1990Argfs)duplicationPathogenicrs276174865GRCh37Chr 13, 32914459: 32914459
755BRCA2NM_000059.3(BRCA2): c.5968_5969delGA (p.Asp1990Cysfs)deletionPathogenicrs80359552GRCh37Chr 13, 32914460: 32914461
756BRCA2NM_000059.3(BRCA2): c.5984dupA (p.Asn1995Lysfs)duplicationPathogenicrs397507818GRCh37Chr 13, 32914476: 32914476
757BRCA2NM_000059.3(BRCA2): c.5992C> T (p.Gln1998Ter)SNVPathogenicrs397507819GRCh37Chr 13, 32914484: 32914484
758BRCA2NM_000059.3(BRCA2): c.5delC (p.Pro2Leufs)deletionPathogenicrs397507820GRCh37Chr 13, 32890602: 32890602
759BRCA2NM_000059.3(BRCA2): c.6001delT (p.Ser2001Leufs)deletionPathogenicrs80359553GRCh37Chr 13, 32914493: 32914493
760BRCA2NM_000059.3(BRCA2): c.6025C> T (p.Gln2009Ter)SNVPathogenicrs80358838GRCh37Chr 13, 32914517: 32914517
761BRCA2NM_000059.3(BRCA2): c.6033_6034delTT (p.Ser2012Glnfs)deletionPathogenicrs397507823GRCh37Chr 13, 32914525: 32914526
762BRCA2NM_000059.3(BRCA2): c.6033_6034insGT (p.Ser2012Valfs)insertionPathogenicrs397507824GRCh37Chr 13, 32914525: 32914526
763BRCA2NM_000059.3(BRCA2): c.6058G> T (p.Glu2020Ter)SNVPathogenicrs80358842GRCh37Chr 13, 32914550: 32914550
764BRCA2NM_000059.3(BRCA2): c.6065C> G (p.Ser2022Ter)SNVPathogenicrs80358843GRCh37Chr 13, 32914557: 32914557
765BRCA2NM_000059.3(BRCA2): c.6068_6072delACCAG (p.Asp2023Alafs)deletionPathogenicrs80359555GRCh37Chr 13, 32914560: 32914564
766BRCA2NM_000059.3(BRCA2): c.6070C> T (p.Gln2024Ter)SNVPathogenicrs80358844GRCh37Chr 13, 32914562: 32914562
767BRCA2NM_000059.3(BRCA2): c.6071delA (p.Gln2024Argfs)deletionPathogenicrs80359556GRCh37Chr 13, 32914563: 32914563
768BRCA2NM_000059.3(BRCA2): c.6078_6079delAA (p.Glu2028Argfs)deletionPathogenicrs80359557GRCh37Chr 13, 32914570: 32914571
769BRCA2NM_000059.3(BRCA2): c.6079dupA (p.Arg2027Lysfs)duplicationPathogenicrs397507826GRCh37Chr 13, 32914571: 32914571
770BRCA2NM_000059.3(BRCA2): c.6082G> T (p.Glu2028Ter)SNVPathogenicrs397507827GRCh37Chr 13, 32914574: 32914574
771BRCA2NM_000059.3(BRCA2): c.6082_6086delGAAGA (p.Glu2028Lysfs)deletionPathogenicrs80359558GRCh37Chr 13, 32914574: 32914578
772BRCA2NM_000059.3(BRCA2): c.6085G> T (p.Glu2029Ter)SNVPathogenicrs397507828GRCh37Chr 13, 32914577: 32914577
773BRCA2NM_000059.3(BRCA2): c.6096dupT (p.Ile2033Tyrfs)duplicationPathogenicrs397507829GRCh37Chr 13, 32914588: 32914588
774BRCA2NM_000059.3(BRCA2): c.6103delA (p.Thr2035Leufs)deletionPathogenicrs80359559GRCh37Chr 13, 32914595: 32914595
775BRCA2NM_000059.3(BRCA2): c.610_613dupCTTA (p.Ser205Thrfs)duplicationPathogenicrs397507830GRCh37Chr 13, 32900729: 32900732
776BRCA2NM_000059.3(BRCA2): c.610delC (p.Ser205Valfs)deletionPathogenicrs80359560GRCh37Chr 13, 32900729: 32900729
777BRCA2NM_000059.3(BRCA2): c.6129dupA (p.Gly2044Argfs)duplicationPathogenicrs80359561GRCh37Chr 13, 32914621: 32914621
778BRCA2NM_000059.3(BRCA2): c.6154delT (p.Ser2052Hisfs)deletionPathogenicrs80359562GRCh37Chr 13, 32914646: 32914646
779BRCA2NM_000059.3(BRCA2): c.6169G> T (p.Gly2057Ter)SNVPathogenicrs80358856GRCh37Chr 13, 32914661: 32914661
780BRCA2NM_000059.3(BRCA2): c.6178delA (p.Thr2060Glnfs)deletionPathogenicrs80359563GRCh37Chr 13, 32914670: 32914670
781BRCA2NM_000059.3(BRCA2): c.6198_6199delTT (p.Ser2067Hisfs)deletionPathogenicrs80359564GRCh37Chr 13, 32914690: 32914691
782BRCA2NM_000059.3(BRCA2): c.6201delC (p.Ile2068Phefs)deletionPathogenicrs80359565GRCh37Chr 13, 32914693: 32914693
783BRCA2NM_000059.3(BRCA2): c.6202dupA (p.Ile2068Asnfs)duplicationPathogenicrs397507833GRCh37Chr 13, 32914694: 32914694
784BRCA2NM_000059.3(BRCA2): c.6209_6212delAAAG (p.Glu2070Valfs)deletionPathogenicrs276174866GRCh37Chr 13, 32914701: 32914704
785BRCA2NM_000059.3(BRCA2): c.6216delC (p.Leu2073Tyrfs)deletionPathogenicrs80359567GRCh37Chr 13, 32914708: 32914708
786BRCA2NM_000059.3(BRCA2): c.6220_6222delCACinsAA (p.His2074Lysfs)indelPathogenicrs276174867GRCh37Chr 13, 32914712: 32914714
787BRCA2NM_000059.3(BRCA2): c.6239T> G (p.Leu2080Ter)SNVPathogenicrs80358864GRCh37Chr 13, 32914731: 32914731
788BRCA2NM_000059.3(BRCA2): c.6240dupA (p.Glu2081Argfs)duplicationPathogenicrs80359570GRCh37Chr 13, 32914732: 32914732
789BRCA2NM_000059.3(BRCA2): c.6268_6269delCA (p.His2090Terfs)deletionPathogenicrs397507836GRCh37Chr 13, 32914760: 32914761
790BRCA2NM_000059.3(BRCA2): c.6270_6271delTA (p.His2090Glnfs)deletionPathogenicrs80359571GRCh37Chr 13, 32914762: 32914763
791BRCA2NM_000059.3(BRCA2): c.6280_6286delTATTCAC (p.Tyr2094Leufs)deletionPathogenicrs80359572GRCh37Chr 13, 32914772: 32914778
792BRCA2NM_000059.3(BRCA2): c.6282_6289delTTCACCTA (p.Ser2095Valfs)deletionPathogenicrs80359573GRCh37Chr 13, 32914774: 32914781
793BRCA2NM_000059.3(BRCA2): c.6302delA (p.Asn2101Metfs)deletionPathogenicrs397507839GRCh37Chr 13, 32914794: 32914794
794BRCA2NM_000059.3(BRCA2): c.6308C> A (p.Ser2103Ter)SNVPathogenicrs80358870GRCh37Chr 13, 32914800: 32914800
795BRCA2NM_000059.3(BRCA2): c.631+4A> GSNVPathogenicrs397507841GRCh37Chr 13, 32900754: 32900754
796BRCA2NM_000059.3(BRCA2): c.631G> A (p.Val211Ile)SNVPathogenicrs80358871GRCh37Chr 13, 32900750: 32900750
797BRCA2NM_000059.3(BRCA2): c.632-1G> ASNVPathogenicrs81002820GRCh37Chr 13, 32903579: 32903579
798BRCA2NM_000059.3(BRCA2): c.632-1G> CSNVPathogenicrs81002820GRCh37Chr 13, 32903579: 32903579
799BRCA2NM_000059.3(BRCA2): c.632-2A> GSNVPathogenicrs397507842GRCh37Chr 13, 32903578: 32903578
800BRCA2NM_000059.3(BRCA2): c.6325_6326delGT (p.Val2109Terfs)deletionPathogenicrs276174871GRCh37Chr 13, 32914817: 32914818
801BRCA2NM_000059.3(BRCA2): c.6335_6336delGA (p.Arg2112Lysfs)deletionPathogenicrs80359574GRCh37Chr 13, 32914827: 32914828
802BRCA2NM_000059.3(BRCA2): c.6352_6353delGT (p.Val2118Lysfs)deletionPathogenicrs80359576GRCh37Chr 13, 32914844: 32914845
803BRCA2NM_000059.3(BRCA2): c.6353_6366delTAAACTCAGAAATG (p.Val2118Glyfs)deletionPathogenicrs397507844GRCh37Chr 13, 32914845: 32914858
804BRCA2NM_000059.3(BRCA2): c.6359C> G (p.Ser2120Ter)SNVPathogenicrs397507845GRCh37Chr 13, 32914851: 32914851
805BRCA2NM_000059.3(BRCA2): c.6373delA (p.Thr2125Profs)deletionPathogenicrs80359578GRCh37Chr 13, 32914865: 32914865
806BRCA2NM_000059.3(BRCA2): c.6382A> T (p.Lys2128Ter)SNVPathogenicrs80358875GRCh37Chr 13, 32914874: 32914874
807BRCA2NM_000059.3(BRCA2): c.6393_6396delATTA (p.Lys2131Asnfs)deletionPathogenicrs397507849GRCh37Chr 13, 32914885: 32914888
808BRCA2NM_000059.3(BRCA2): c.63delA (p.Ala22Glnfs)deletionPathogenicrs80359582GRCh37Chr 13, 32890660: 32890660
809BRCA2NM_000059.3(BRCA2): c.6401_6404delATAA (p.Asn2134Thrfs)deletionPathogenicrs80359583GRCh37Chr 13, 32914893: 32914896
810BRCA2NM_000059.3(BRCA2): c.6407_6411delTAAAT (p.Leu2136Cysfs)deletionPathogenicrs80359586GRCh37Chr 13, 32914899: 32914903
811BRCA2NM_000059.3(BRCA2): c.6408_6414delAAATGTT (p.Asn2137Lysfs)deletionPathogenicrs397507851GRCh37Chr 13, 32914900: 32914906
812BRCA2NM_000059.3(BRCA2): c.6420_6421insA (p.Gly2141Argfs)insertionPathogenicrs397507852GRCh37Chr 13, 32914912: 32914913
813BRCA2NM_000059.3(BRCA2): c.6422dupG (p.Ser2142Phefs)duplicationPathogenicrs397507853GRCh37Chr 13, 32914914: 32914914
814BRCA2NM_000059.3(BRCA2): c.6443_6444delCT (p.Ser2148Tyrfs)deletionPathogenicrs80359589GRCh37Chr 13, 32914935: 32914936
815BRCA2NM_000059.3(BRCA2): c.6444_6447delTATT (p.Ile2149Lysfs)deletionPathogenicrs80359591GRCh37Chr 13, 32914936: 32914939
816BRCA2NM_000059.3(BRCA2): c.6445_6446delAT (p.Ile2149Terfs)deletionPathogenicrs80359592GRCh37Chr 13, 32914937: 32914938
817BRCA2NM_000059.3(BRCA2): c.6447_6448dupTA (p.Lys2150Ilefs)duplicationPathogenicrs397507858GRCh37Chr 13, 32914939: 32914940
818BRCA2NM_000059.3(BRCA2): c.6449_6450delAA (p.Lys2150Serfs)deletionPathogenicrs80359594GRCh37Chr 13, 32914941: 32914942
819BRCA2NM_000059.3(BRCA2): c.6450dupA (p.Val2151Serfs)duplicationPathogenicrs80359595GRCh37Chr 13, 32914942: 32914942
820BRCA2NM_000059.3(BRCA2): c.6462T> G (p.Tyr2154Ter)SNVPathogenicrs80358883GRCh37Chr 13, 32914954: 32914954
821BRCA2NM_000059.3(BRCA2): c.6469C> T (p.Gln2157Ter)SNVPathogenicrs397507859GRCh37Chr 13, 32914961: 32914961
822BRCA2NM_000059.3(BRCA2): c.6490_6492delCAGinsGACT (p.Gln2164Aspfs)indelPathogenicrs397507861GRCh37Chr 13, 32914982: 32914984
823BRCA2NM_000059.3(BRCA2): c.6490delC (p.Gln2164Serfs)deletionPathogenicrs80359599GRCh37Chr 13, 32914982: 32914982
824BRCA2NM_000059.3(BRCA2): c.6491_6494delAGTT (p.Gln2164Argfs)deletionPathogenicrs397507862GRCh37Chr 13, 32914983: 32914986
825BRCA2NM_000059.3(BRCA2): c.6494delT (p.Leu2165Trpfs)deletionPathogenicrs276174874GRCh37Chr 13, 32914986: 32914986
826BRCA2NM_000059.3(BRCA2): c.6509_6510delAA (p.Lys2170Serfs)deletionPathogenicrs80359600GRCh37Chr 13, 32915001: 32915002
827BRCA2NM_000059.3(BRCA2): c.652G> T (p.Glu218Ter)SNVPathogenicrs80358884GRCh37Chr 13, 32903600: 32903600
828BRCA2NM_000059.3(BRCA2): c.6531_6534delTCAT (p.Ile2177Metfs)deletionPathogenicrs397507865GRCh37Chr 13, 32915023: 32915026
829BRCA2NM_000059.3(BRCA2): c.6547G> T (p.Glu2183Ter)SNVPathogenicrs397507866GRCh37Chr 13, 32915039: 32915039
830BRCA2NM_000059.3(BRCA2): c.6553delG (p.Ala2185Leufs)deletionPathogenicrs80359603GRCh37Chr 13, 32915045: 32915045
831BRCA2NM_000059.3(BRCA2): c.6557C> A (p.Ser2186Ter)SNVPathogenicrs397507867GRCh37Chr 13, 32915049: 32915049
832BRCA2NM_000059.3(BRCA2): c.6601delT (p.Ser2201Leufs)deletionPathogenicrs397507869GRCh37Chr 13, 32915093: 32915093
833BRCA2NM_000059.3(BRCA2): c.6603_6604delTG (p.Asp2202Cysfs)deletionPathogenicrs80359608GRCh37Chr 13, 32915095: 32915096
834BRCA2NM_000059.3(BRCA2): c.6626_6627delTA (p.Ile2209Argfs)deletionPathogenicrs80359610GRCh37Chr 13, 32915118: 32915119
835BRCA2NM_000059.3(BRCA2): c.6629_6630delAA (p.Glu2210Glyfs)deletionPathogenicrs80359611GRCh37Chr 13, 32915121: 32915122
836BRCA2NM_000059.3(BRCA2): c.662_663delTT (p.Phe221Serfs)deletionPathogenicrs80359609GRCh37Chr 13, 32903610: 32903611
837BRCA2NM_000059.3(BRCA2): c.6634_6637delTGTT (p.Cys2212Leufs)deletionPathogenicrs397507871GRCh37Chr 13, 32915126: 32915129
838BRCA2NM_000059.3(BRCA2): c.6638delC (p.Ser2213Leufs)deletionPathogenicrs80359612GRCh37Chr 13, 32915130: 32915130
839BRCA2NM_000059.3(BRCA2): c.6643delT (p.Tyr2215Thrfs)deletionPathogenicrs80359614GRCh37Chr 13, 32915135: 32915135
840BRCA2NM_000059.3(BRCA2): c.6644dupA (p.Tyr2215Terfs)duplicationPathogenicrs80359615GRCh37Chr 13, 32915136: 32915136
841BRCA2NM_000059.3(BRCA2): c.6656C> G (p.Ser2219Ter)SNVPathogenicrs80358893GRCh37Chr 13, 32915148: 32915148
842BRCA2NM_000059.3(BRCA2): c.6658_6661delGAAA (p.Glu2220Thrfs)deletionPathogenicrs80359617GRCh37Chr 13, 32915150: 32915153
843BRCA2NM_000059.3(BRCA2): c.6673delA (p.Thr2225Glnfs)deletionPathogenicrs276174875GRCh37Chr 13, 32915165: 32915165
844BRCA2NM_000059.3(BRCA2): c.6676_6677delGA (p.Glu2226Serfs)deletionPathogenicrs80359619GRCh37Chr 13, 32915168: 32915169
845BRCA2NM_000059.3(BRCA2): c.6678delA (p.Ala2227Glnfs)deletionPathogenicrs80359620GRCh37Chr 13, 32915170: 32915170
846BRCA2NM_000059.3(BRCA2): c.6682dupG (p.Val2228Glyfs)duplicationPathogenicrs80359621GRCh37Chr 13, 32915174: 32915174
847BRCA2NM_000059.3(BRCA2): c.6688delA (p.Ile2230Leufs)deletionPathogenicrs397507877GRCh37Chr 13, 32915180: 32915180
848BRCA2NM_000059.3(BRCA2): c.67+1G> ASNVPathogenicrs81002796GRCh37Chr 13, 32890665: 32890665
849BRCA2NM_000059.3(BRCA2): c.67+2T> ASNVPathogenicrs81002885GRCh37Chr 13, 32890666: 32890666
850BRCA2NM_000059.3(BRCA2): c.6715G> T (p.Glu2239Ter)SNVPathogenicrs276174876GRCh37Chr 13, 32915207: 32915207
851BRCA2NM_000059.3(BRCA2): c.6732delA (p.Lys2244Asnfs)deletionPathogenicrs397507879GRCh37Chr 13, 32915224: 32915224
852BRCA2NM_000059.3(BRCA2): c.673_676delACTA (p.Thr225Leufs)deletionPathogenicrs397507880GRCh37Chr 13, 32903621: 32903624
853BRCA2NM_000059.3(BRCA2): c.6743_6755delATGCCACACATTC (p.His2248Leufs)deletionPathogenicrs80359622GRCh37Chr 13, 32915235: 32915247
854BRCA2NM_000059.3(BRCA2): c.6754dupT (p.Ser2252Phefs)duplicationPathogenicrs180670511GRCh37Chr 13, 32915246: 32915246
855BRCA2NM_000059.3(BRCA2): c.6768T> A (p.Cys2256Ter)SNVPathogenicrs80358901GRCh37Chr 13, 32915260: 32915260
856BRCA2NM_000059.3(BRCA2): c.67G> T (p.Asp23Tyr)SNVPathogenicrs397507881GRCh37Chr 13, 32890664: 32890664
857BRCA2NM_000059.3(BRCA2): c.6809delG (p.Gly2270Glufs)deletionPathogenicrs80359625GRCh37Chr 13, 32915301: 32915301
858BRCA2NM_000059.3(BRCA2): c.681+4A> GSNVPathogenicrs397507884GRCh37Chr 13, 32903633: 32903633
859BRCA2NM_000059.3(BRCA2): c.6814delA (p.Arg2272Glufs)deletionPathogenicrs397507885GRCh37Chr 13, 32915306: 32915306
860BRCA2NM_000059.3(BRCA2): c.6816_6817delAA (p.Gly2274Argfs)deletionPathogenicrs397507886GRCh37Chr 13, 32915308: 32915309
861BRCA2NM_000059.3(BRCA2): c.682-1G> CSNVLikely pathogenic, Pathogenicrs81002831GRCh37Chr 13, 32905055: 32905055
862BRCA2NM_000059.3(BRCA2): c.6833_6837delTCTTA (p.Ile2278Serfs)deletionPathogenicrs80359626GRCh37Chr 13, 32915325: 32915329
863BRCA2NM_000059.3(BRCA2): c.6841+1delGdeletionPathogenicrs397507887GRCh37Chr 13, 32915334: 32915334
864BRCA2NM_000059.3(BRCA2): c.6938-2A> GSNVLikely pathogenic, Pathogenicrs81002863GRCh37Chr 13, 32920962: 32920962
865BRCA2NM_000059.3(BRCA2): c.6959delT (p.Leu2320Cysfs)deletionPathogenicrs397507888GRCh37Chr 13, 32920985: 32920985
866BRCA2NM_000059.3(BRCA2): c.6990_6994delTACCT (p.Ile2330Metfs)deletionPathogenicrs80359631GRCh37Chr 13, 32921016: 32921020
867BRCA2NM_000059.3(BRCA2): c.7003_7007delTTTCG (p.Phe2335Hisfs)deletionPathogenicrs80359632GRCh37Chr 13, 32921029: 32921033
868BRCA2NM_000059.3(BRCA2): c.7007+1G> CSNVPathogenicrs397507891GRCh37Chr 13, 32921034: 32921034
869BRCA2NM_000059.3(BRCA2): c.7007G> C (p.Arg2336Pro)SNVPathogenicrs28897743GRCh37Chr 13, 32921033: 32921033
870BRCA2NM_000059.3(BRCA2): c.7008-2A> GSNVPathogenicrs81002823GRCh37Chr 13, 32928996: 32928996
871BRCA2NM_000059.3(BRCA2): c.7008-2A> TSNVPathogenicrs81002823GRCh37Chr 13, 32928996: 32928996
872BRCA2NM_000059.3(BRCA2): c.7024C> T (p.Gln2342Ter)SNVPathogenicrs80358928GRCh37Chr 13, 32929014: 32929014
873BRCA2NM_000059.3(BRCA2): c.702delC (p.Asn235Ilefs)deletionPathogenicrs397507892GRCh37Chr 13, 32905076: 32905076
874BRCA2NM_000059.3(BRCA2): c.7032dupA (p.Gln2345Thrfs)duplicationPathogenicrs80359635GRCh37Chr 13, 32929022: 32929022
875BRCA2NM_000059.3(BRCA2): c.7047delT (p.Phe2349Leufs)deletionPathogenicrs397507893GRCh37Chr 13, 32929037: 32929037
876BRCA2NM_000059.3(BRCA2): c.7060C> T (p.Gln2354Ter)SNVPathogenicrs80358936GRCh37Chr 13, 32929050: 32929050
877BRCA2NM_000059.3(BRCA2): c.7092delA (p.Glu2364Aspfs)deletionPathogenicrs397507896GRCh37Chr 13, 32929082: 32929082
878BRCA2NM_000059.3(BRCA2): c.7110delA (p.Lys2370Asnfs)deletionPathogenicrs397507897GRCh37Chr 13, 32929100: 32929100
879BRCA2NM_000059.3(BRCA2): c.7115C> G (p.Ser2372Ter)SNVPathogenicrs80358943GRCh37Chr 13, 32929105: 32929105
880BRCA2NM_000059.3(BRCA2): c.7151_7152delAA (p.Gln2384Argfs)deletionPathogenicrs276174890GRCh37Chr 13, 32929141: 32929142
881BRCA2NM_000059.3(BRCA2): c.7156dupT (p.Ser2386Phefs)duplicationPathogenicrs80359639GRCh37Chr 13, 32929146: 32929146
882BRCA2NM_000059.3(BRCA2): c.7177dupA (p.Met2393Asnfs)duplicationPathogenicrs397507899GRCh37Chr 13, 32929167: 32929167
883BRCA2NM_000059.3(BRCA2): c.7180A> T (p.Arg2394Ter)SNVPathogenicrs80358946GRCh37Chr 13, 32929170: 32929170
884BRCA2NM_000059.3(BRCA2): c.7183delC (p.His2395Thrfs)deletionPathogenicrs397507900GRCh37Chr 13, 32929173: 32929173
885BRCA2NM_000059.3(BRCA2): c.71delT (p.Leu24Terfs)deletionPathogenicrs397507903GRCh37Chr 13, 32893217: 32893217
886BRCA2NM_000059.3(BRCA2): c.7208_7211delCCAA (p.Thr2403Lysfs)deletionPathogenicrs80359641GRCh37Chr 13, 32929198: 32929201
887BRCA2NM_000059.3(BRCA2): c.7211_7212delAA (p.Lys2404Serfs)deletionPathogenicrs80359642GRCh37Chr 13, 32929201: 32929202
888BRCA2NM_000059.3(BRCA2): c.7226delC (p.Pro2409Leufs)deletionPathogenicrs80359643GRCh37Chr 13, 32929216: 32929216
889BRCA2NM_000059.3(BRCA2): c.7234_7235insG (p.Thr2412Serfs)insertionPathogenicrs397507906GRCh37Chr 13, 32929224: 32929225
890BRCA2NM_000059.3(BRCA2): c.7241C> G (p.Ser2414Ter)SNVPathogenicrs80358951GRCh37Chr 13, 32929231: 32929231
891BRCA2NM_000059.3(BRCA2): c.7254_7255delAG (p.Arg2418Serfs)deletionPathogenicrs80359644GRCh37Chr 13, 32929244: 32929245
892BRCA2NM_000059.3(BRCA2): c.7261C> T (p.Gln2421Ter)SNVPathogenicrs397507908GRCh37Chr 13, 32929251: 32929251
893BRCA2NM_000059.3(BRCA2): c.7303C> T (p.Gln2435Ter)SNVPathogenicrs397507910GRCh37Chr 13, 32929293: 32929293
894BRCA2NM_000059.3(BRCA2): c.7322delG (p.Gly2441Alafs)deletionPathogenicrs397507911GRCh37Chr 13, 32929312: 32929312
895BRCA2NM_000059.3(BRCA2): c.733A> T (p.Arg245Ter)SNVPathogenicrs80358959GRCh37Chr 13, 32905107: 32905107
896BRCA2NM_000059.3(BRCA2): c.7360delA (p.Ile2454Phefs)deletionPathogenicrs80359646GRCh37Chr 13, 32929350: 32929350
897BRCA2NM_000059.3(BRCA2): c.7375A> T (p.Lys2459Ter)SNVPathogenicrs397507913GRCh37Chr 13, 32929365: 32929365
898BRCA2NM_000059.3(BRCA2): c.7379delA (p.Asn2460Thrfs)deletionPathogenicrs397507914GRCh37Chr 13, 32929369: 32929369
899BRCA2NM_000059.3(BRCA2): c.7408_7409delTT (p.Phe2470Hisfs)deletionPathogenicrs397507915GRCh37Chr 13, 32929398: 32929399
900BRCA2NM_000059.3(BRCA2): c.7409dupT (p.Thr2471Hisfs)duplicationPathogenicrs397507916GRCh37Chr 13, 32929399: 32929399
901BRCA2NM_000059.3(BRCA2): c.7436-2A> TSNVPathogenicrs397507917GRCh37Chr 13, 32930563: 32930563
902BRCA2NM_000059.3(BRCA2): c.7443delT (p.Thr2482Glnfs)deletionPathogenicrs80359652GRCh37Chr 13, 32930572: 32930572
903BRCA2NM_000059.3(BRCA2): c.7467dupT (p.Ile2490Tyrfs)duplicationPathogenicrs397507918GRCh37Chr 13, 32930596: 32930596
904BRCA2NM_000059.3(BRCA2): c.7471C> T (p.Gln2491Ter)SNVPathogenicrs80358971GRCh37Chr 13, 32930600: 32930600
905BRCA2NM_000059.3(BRCA2): c.7474_7475delGA (p.Asp2492Tyrfs)deletionPathogenicrs80359653GRCh37Chr 13, 32930603: 32930604
906BRCA2NM_000059.3(BRCA2): c.748delG (p.Val250Terfs)deletionPathogenicrs80359654GRCh37Chr 13, 32905122: 32905122
907BRCA2NM_000059.3(BRCA2): c.7538delC (p.Ala2513Glufs)deletionPathogenicrs397507919GRCh37Chr 13, 32930667: 32930667
908BRCA2NM_000059.3(BRCA2): c.7543delA (p.Thr2515Hisfs)deletionPathogenicrs80359658GRCh37Chr 13, 32930672: 32930672
909BRCA2NM_000059.3(BRCA2): c.7544delC (p.Thr2515Asnfs)deletionPathogenicrs397507920GRCh37Chr 13, 32930673: 32930673
910BRCA2NM_000059.3(BRCA2): c.755delA (p.Asp252Alafs)deletionPathogenicrs80359661GRCh37Chr 13, 32905129: 32905129
911BRCA2NM_000059.3(BRCA2): c.756_759delCAGT (p.Asp252Glufs)deletionPathogenicrs80359663GRCh37Chr 13, 32905130: 32905133
912BRCA2NM_000059.3(BRCA2): c.7593delT (p.Ser2533Leufs)deletionPathogenicrs80359665GRCh37Chr 13, 32930722: 32930722
913BRCA2NM_000059.3(BRCA2): c.7612A> T (p.Lys2538Ter)SNVPathogenicrs397507921GRCh37Chr 13, 32930741: 32930741
914BRCA2NM_000059.3(BRCA2): c.7617+1G> TSNVPathogenicrs397507922GRCh37Chr 13, 32930747: 32930747
915BRCA2NM_000059.3(BRCA2): c.7647C> A (p.Cys2549Ter)SNVPathogenicrs80358993GRCh37Chr 13, 32931908: 32931908
916BRCA2NM_000059.3(BRCA2): c.7655_7658delTTAA (p.Ile2552Thrfs)deletionPathogenicrs80359669GRCh37Chr 13, 32931916: 32931919
917BRCA2NM_000059.3(BRCA2): c.7671delA (p.Glu2558Serfs)deletionPathogenicrs397507928GRCh37Chr 13, 32931932: 32931932
918BRCA2NM_000059.3(BRCA2): c.7679_7680delTT (p.Phe2560Serfs)deletionPathogenicrs80359673GRCh37Chr 13, 32931940: 32931941
919BRCA2NM_000059.3(BRCA2): c.767_768delCA (p.Thr256Lysfs)deletionPathogenicrs80359670GRCh37Chr 13, 32905141: 32905142
920BRCA2NM_000059.3(BRCA2): c.767delC (p.Thr256Lysfs)deletionPathogenicrs397507930GRCh37Chr 13, 32905141: 32905141
921BRCA2NM_000059.3(BRCA2): c.7680dupT (p.Gln2561Serfs)duplicationPathogenicrs397507932GRCh37Chr 13, 32931941: 32931941
922BRCA2NM_000059.3(BRCA2): c.7681C> T (p.Gln2561Ter)SNVPathogenicrs80358994GRCh37Chr 13, 32931942: 32931942
923BRCA2NM_000059.3(BRCA2): c.7681_7682insT (p.Gln2561Leufs)insertionPathogenicrs397507933GRCh37Chr 13, 32931942: 32931943
924BRCA2NM_000059.3(BRCA2): c.7689delC (p.His2563Glnfs)deletionPathogenicrs80359674GRCh37Chr 13, 32931950: 32931950
925BRCA2NM_000059.3(BRCA2): c.7697dupA (p.Asp2566Glufs)duplicationPathogenicrs397507934GRCh37Chr 13, 32931958: 32931958
926BRCA2NM_000059.3(BRCA2): c.7707delT (p.Lys2570Argfs)deletionPathogenicrs397507935GRCh37Chr 13, 32931968: 32931968
927BRCA2NM_000059.3(BRCA2): c.7721G> A (p.Trp2574Ter)SNVPathogenicrs80358997GRCh37Chr 13, 32931982: 32931982
928BRCA2NM_000059.3(BRCA2): c.7738C> T (p.Gln2580Ter)SNVPathogenicrs80358999GRCh37Chr 13, 32931999: 32931999
929BRCA2NM_000059.3(BRCA2): c.7751delG (p.Gly2584Valfs)deletionPathogenicrs397507936GRCh37Chr 13, 32932012: 32932012
930BRCA2NM_000059.3(BRCA2): c.775delA (p.Arg259Glufs)deletionPathogenicrs75096777GRCh37Chr 13, 32905149: 32905149
931BRCA2NM_000059.3(BRCA2): c.7761delC (p.Ile2588Tyrfs)deletionPathogenicrs80359678GRCh37Chr 13, 32932022: 32932022
932BRCA2NM_000059.3(BRCA2): c.7805+1G> ASNVLikely pathogenic, Pathogenicrs81002809GRCh37Chr 13, 32932067: 32932067
933BRCA2NM_000059.3(BRCA2): c.7805G> C (p.Arg2602Thr)SNVPathogenicrs397507938GRCh37Chr 13, 32932066: 32932066
934BRCA2NM_000059.3(BRCA2): c.7806-1G> TSNVPathogenicrs81002860GRCh37Chr 13, 32936659: 32936659
935BRCA2NM_000059.3(BRCA2): c.7806_7807insAG (p.Ala2603Argfs)insertionPathogenicrs80359683GRCh37Chr 13, 32936660: 32936661
936BRCA2NM_000059.3(BRCA2): c.7846delT (p.Ser2616Leufs)deletionPathogenicrs397507940GRCh37Chr 13, 32936700: 32936700
937BRCA2NM_000059.3(BRCA2): c.7847delC (p.Ser2616Leufs)deletionPathogenicrs80359685GRCh37Chr 13, 32936701: 32936701
938BRCA2NM_000059.3(BRCA2): c.7863T> A (p.Tyr2621Ter)SNVPathogenicrs276174896GRCh37Chr 13, 32936717: 32936717
939BRCA2NM_000059.3(BRCA2): c.7872_7873delTA (p.Tyr2624Terfs)deletionPathogenicrs397507942GRCh37Chr 13, 32936726: 32936727
940BRCA2NM_000059.3(BRCA2): c.7884dupA (p.Trp2629Metfs)duplicationPathogenicrs397507943GRCh37Chr 13, 32936738: 32936738
941BRCA2NM_000059.3(BRCA2): c.7886G> A (p.Trp2629Ter)SNVPathogenicrs80359015GRCh37Chr 13, 32936740: 32936740
942BRCA2NM_000059.3(BRCA2): c.7908T> A (p.Cys2636Ter)SNVPathogenicrs80359016GRCh37Chr 13, 32936762: 32936762
943BRCA2NM_000059.3(BRCA2): c.793+1G> ASNVPathogenicrs81002846GRCh37Chr 13, 32905168: 32905168
944BRCA2NM_000059.3(BRCA2): c.793+1G> TSNVPathogenicrs81002846GRCh37Chr 13, 32905168: 32905168
945BRCA2NM_000059.3(BRCA2): c.7934delG (p.Arg2645Asnfs)deletionPathogenicrs80359688GRCh37Chr 13, 32936788: 32936788
946BRCA2NM_000059.3(BRCA2): c.7954delG (p.Val2652Cysfs)deletionPathogenicrs80359689GRCh37Chr 13, 32936808: 32936808
947BRCA2NM_000059.3(BRCA2): c.7958T> C (p.Leu2653Pro)SNVLikely pathogenic, Pathogenicrs80359022GRCh37Chr 13, 32936812: 32936812
948BRCA2NM_000059.3(BRCA2): c.7976+1G> ASNVLikely pathogenic, Pathogenicrs81002873GRCh37Chr 13, 32936831: 32936831
949BRCA2NM_000059.3(BRCA2): c.7976+3_7976+4delAAdeletionPathogenicrs397507946GRCh37Chr 13, 32936833: 32936834
950BRCA2NM_000059.3(BRCA2): c.7976G> C (p.Arg2659Thr)SNVPathogenicrs80359027GRCh37Chr 13, 32936830: 32936830
951BRCA2NM_000059.3(BRCA2): c.7977-2delAdeletionPathogenicrs397507947GRCh37Chr 13, 32937314: 32937314
952BRCA2NM_000059.3(BRCA2): c.7977-7C> GSNVPathogenicrs397507948GRCh37Chr 13, 32937309: 32937309
953BRCA2NM_000059.3(BRCA2): c.7980T> G (p.Tyr2660Ter)SNVPathogenicrs397507949GRCh37Chr 13, 32937319: 32937319
954BRCA2NM_000059.3(BRCA2): c.7980_7984delTGATA (p.Asp2661Glyfs)deletionPathogenicrs397507950GRCh37Chr 13, 32937319: 32937323
955BRCA2NM_000059.3(BRCA2): c.7988A> T (p.Glu2663Val)SNVPathogenicrs80359031GRCh37Chr 13, 32937327: 32937327
956BRCA2NM_000059.3(BRCA2): c.7996A> T (p.Arg2666Ter)SNVPathogenicrs80359032GRCh37Chr 13, 32937335: 32937335
957BRCA2NM_000059.3(BRCA2): c.8002A> T (p.Arg2668Ter)SNVPathogenicrs276174900GRCh37Chr 13, 32937341: 32937341
958BRCA2NM_000059.3(BRCA2): c.8002_8008dupAGAAGAT (p.Ser2670Terfs)duplicationPathogenicrs397507951GRCh37Chr 13, 32937341: 32937347
959BRCA2NM_000059.3(BRCA2): c.8009C> A (p.Ser2670Ter)SNVPathogenicrs80359035GRCh37Chr 13, 32937348: 32937348
960BRCA2NM_000059.3(BRCA2): c.8020_8021delAA (p.Lys2674Aspfs)deletionPathogenicrs397507952GRCh37Chr 13, 32937359: 32937360
961BRCA2NM_000059.3(BRCA2): c.8021delA (p.Lys2674Argfs)deletionPathogenicrs397507953GRCh37Chr 13, 32937360: 32937360
962BRCA2NM_000059.3(BRCA2): c.8029_8030delGA (p.Glu2677Lysfs)deletionPathogenicrs397507955GRCh37Chr 13, 32937368: 32937369
963BRCA2NM_000059.3(BRCA2): c.8029delG (p.Glu2677Lysfs)deletionPathogenicrs80359691GRCh37Chr 13, 32937368: 32937368
964BRCA2NM_000059.3(BRCA2): c.8032_8033dupAG (p.Asp2679Glyfs)duplicationPathogenicrs397507956GRCh37Chr 13, 32937371: 32937372
965BRCA2NM_000059.3(BRCA2): c.8042_8043delCA (p.Thr2681Serfs)deletionPathogenicrs276174901GRCh37Chr 13, 32937381: 32937382
966BRCA2NM_000059.3(BRCA2): c.8047_8054dupGCAAAAAC (p.Leu2686Glnfs)duplicationPathogenicrs397507957GRCh37Chr 13, 32937386: 32937393
967BRCA2NM_000059.3(BRCA2): c.8053delA (p.Thr2685Hisfs)deletionPathogenicrs397507958GRCh37Chr 13, 32937392: 32937392
968BRCA2NM_000059.3(BRCA2): c.8058delT (p.Val2687Phefs)deletionPathogenicrs80359692GRCh37Chr 13, 32937397: 32937397
969BRCA2NM_000059.3(BRCA2): c.8064_8065delCT (p.Val2690Phefs)deletionPathogenicrs397507961GRCh37Chr 13, 32937403: 32937404
970BRCA2NM_000059.3(BRCA2): c.8067T> A (p.Cys2689Ter)SNVPathogenicrs80359046GRCh37Chr 13, 32937406: 32937406
971BRCA2NM_000059.3(BRCA2): c.8067delT (p.Cys2689Trpfs)deletionPathogenicrs80359693GRCh37Chr 13, 32937406: 32937406
972BRCA2NM_000059.3(BRCA2): c.8068_8069delGT (p.Val2690Phefs)deletionPathogenicrs80359694GRCh37Chr 13, 32937407: 32937408
973BRCA2NM_000059.3(BRCA2): c.8072_8073delCT (p.Ser2691Terfs)deletionPathogenicrs397507963GRCh37Chr 13, 32937411: 32937412
974BRCA2NM_000059.3(BRCA2): c.8084C> G (p.Ser2695Ter)SNVPathogenicrs80359048GRCh37Chr 13, 32937423: 32937423
975BRCA2NM_000059.3(BRCA2): c.8087T> A (p.Leu2696Ter)SNVPathogenicrs80359050GRCh37Chr 13, 32937426: 32937426
976BRCA2NM_000059.3(BRCA2): c.8087delT (p.Leu2696Terfs)deletionPathogenicrs80359695GRCh37Chr 13, 32937426: 32937426
977BRCA2NM_000059.3(BRCA2): c.809C> G (p.Ser270Ter)SNVPathogenicrs276174902GRCh37Chr 13, 32906424: 32906424
978BRCA2NM_000059.3(BRCA2): c.8130delT (p.Ser2710Argfs)deletionPathogenicrs80359696GRCh37Chr 13, 32937469: 32937469
979BRCA2NM_000059.3(BRCA2): c.8140C> T (p.Gln2714Ter)SNVPathogenicrs80359058GRCh37Chr 13, 32937479: 32937479
980BRCA2NM_000059.3(BRCA2): c.8172_8175dupGTGG (p.Tyr2726Valfs)duplicationPathogenicrs397507964GRCh37Chr 13, 32937511: 32937514
981BRCA2NM_000059.3(BRCA2): c.818C> A (p.Ser273Ter)SNVPathogenicrs80359068GRCh37Chr 13, 32906433: 32906433
982BRCA2NM_000059.3(BRCA2): c.818C> G (p.Ser273Ter)SNVPathogenicrs80359068GRCh37Chr 13, 32906433: 32906433
983BRCA2NM_000059.3(BRCA2): c.8195T> G (p.Leu2732Ter)SNVPathogenicrs397507967GRCh37Chr 13, 32937534: 32937534
984BRCA2NM_000059.3(BRCA2): c.8206dupC (p.Leu2736Profs)duplicationPathogenicrs397507968GRCh37Chr 13, 32937545: 32937545
985BRCA2NM_000059.3(BRCA2): c.8207delT (p.Leu2736Profs)deletionPathogenicrs397507969GRCh37Chr 13, 32937546: 32937546
986BRCA2NM_000059.3(BRCA2): c.8234_8237delTGAC (p.Leu2745Glnfs)deletionPathogenicrs80359699GRCh37Chr 13, 32937573: 32937576
987BRCA2NM_000059.3(BRCA2): c.8234dupT (p.Thr2746Aspfs)duplicationPathogenicrs276174903GRCh37Chr 13, 32937573: 32937573
988BRCA2NM_000059.3(BRCA2): c.8237_8238delCA (p.Thr2746Serfs)deletionPathogenicrs80359700GRCh37Chr 13, 32937576: 32937577
989BRCA2NM_000059.3(BRCA2): c.8243G> A (p.Gly2748Asp)SNVPathogenicrs80359071GRCh37Chr 13, 32937582: 32937582
990BRCA2NM_000059.3(BRCA2): c.8247_8248delGA (p.Lys2750Aspfs)deletionPathogenicrs80359701GRCh37Chr 13, 32937586: 32937587
991BRCA2NM_000059.3(BRCA2): c.8285delC (p.Pro2762Leufs)deletionPathogenicrs397507972GRCh37Chr 13, 32937624: 32937624
992BRCA2NM_000059.3(BRCA2): c.8298_8299dupAC (p.Pro2767Hisfs)duplicationPathogenicrs397507973GRCh37Chr 13, 32937637: 32937638
993BRCA2NM_000059.3(BRCA2): c.8314G> T (p.Glu2772Ter)SNVPathogenicrs397507975GRCh37Chr 13, 32937653: 32937653
994BRCA2NM_000059.3(BRCA2): c.8327T> G (p.Leu2776Ter)SNVPathogenicrs397507977GRCh37Chr 13, 32937666: 32937666
995BRCA2NM_000059.3(BRCA2): c.8331+1G> TSNVPathogenicrs81002837GRCh37Chr 13, 32937671: 32937671
996BRCA2NM_000059.3(BRCA2): c.8340_8343delTAAC (p.Asn2781Valfs)deletionPathogenicrs80359707GRCh37Chr 13, 32944547: 32944550
997BRCA2NM_000059.3(BRCA2): c.8343delC (p.Asn2781Lysfs)deletionPathogenicrs80359708GRCh37Chr 13, 32944550: 32944550
998BRCA2NM_000059.3(BRCA2): c.8363G> A (p.Trp2788Ter)SNVPathogenicrs80359080GRCh37Chr 13, 32944570: 32944570
999BRCA2NM_000059.3(BRCA2): c.8364G> A (p.Trp2788Ter)SNVPathogenicrs397507981GRCh37Chr 13, 32944571: 32944571
1000BRCA2NM_000059.3(BRCA2): c.8394_8396delTAGinsAA (p.Arg2799Asnfs)indelPathogenicrs276174907GRCh37Chr 13, 32944601: 32944603
1001BRCA2NM_000059.3(BRCA2): c.8395delA (p.Arg2799Aspfs)deletionPathogenicrs80359709GRCh37Chr 13, 32944602: 32944602
1002BRCA2NM_000059.3(BRCA2): c.8436dupA (p.Gly2813Argfs)duplicationPathogenicrs80359710GRCh37Chr 13, 32944643: 32944643
1003BRCA2NM_000059.3(BRCA2): c.8451T> A (p.Cys2817Ter)SNVPathogenicrs397507987GRCh37Chr 13, 32944658: 32944658
1004BRCA2NM_000059.3(BRCA2): c.8463dupT (p.Ile2822Tyrfs)duplicationPathogenicrs397507988GRCh37Chr 13, 32944670: 32944670
1005BRCA2NM_000059.3(BRCA2): c.8474delC (p.Ala2825Aspfs)deletionPathogenicrs80359711GRCh37Chr 13, 32944681: 32944681
1006BRCA2NM_000059.3(BRCA2): c.8485C> T (p.Gln2829Ter)SNVPathogenicrs80359099GRCh37Chr 13, 32944692: 32944692
1007BRCA2NM_000059.3(BRCA2): c.8489G> A (p.Trp2830Ter)SNVPathogenicrs80359101GRCh37Chr 13, 32945094: 32945094
1008BRCA2NM_000059.3(BRCA2): c.8504C> A (p.Ser2835Ter)SNVPathogenicrs80359102GRCh37Chr 13, 32945109: 32945109
1009BRCA2NM_000059.3(BRCA2): c.8505delA (p.Ser2836Leufs)deletionPathogenicrs80359713GRCh37Chr 13, 32945110: 32945110
1010BRCA2NM_000059.3(BRCA2): c.8535_8538delAGAG (p.Glu2846Lysfs)deletionPathogenicrs80359715GRCh37Chr 13, 32945140: 32945143
1011BRCA2NM_000059.3(BRCA2): c.8546delA (p.Lys2849Argfs)deletionPathogenicrs397507991GRCh37Chr 13, 32945151: 32945151
1012BRCA2NM_000059.3(BRCA2): c.8560delT (p.Tyr2854Metfs)deletionPathogenicrs80359717GRCh37Chr 13, 32945165: 32945165
1013BRCA2NM_000059.3(BRCA2): c.8561dupA (p.Tyr2854Terfs)duplicationPathogenicrs397507992GRCh37Chr 13, 32945166: 32945166
1014BRCA2NM_000059.3(BRCA2): c.8572C> T (p.Gln2858Ter)SNVPathogenicrs80359112GRCh37Chr 13, 32945177: 32945177
1015BRCA2NM_000059.3(BRCA2): c.8579delA (p.Lys2860Argfs)deletionPathogenicrs397507993GRCh37Chr 13, 32945184: 32945184
1016BRCA2NM_000059.3(BRCA2): c.8594T> A (p.Leu2865Ter)SNVPathogenicrs80359118GRCh37Chr 13, 32945199: 32945199
1017BRCA2NM_000059.3(BRCA2): c.8620G> T (p.Glu2874Ter)SNVPathogenicrs397507996GRCh37Chr 13, 32945225: 32945225
1018BRCA2NM_000059.3(BRCA2): c.8629G> T (p.Glu2877Ter)SNVPathogenicrs80359121GRCh37Chr 13, 32945234: 32945234
1019BRCA2NM_000059.3(BRCA2): c.8632+1G> ASNVLikely pathogenic, Pathogenicrs397507997GRCh37Chr 13, 32945238: 32945238
1020BRCA2NM_000059.3(BRCA2): c.8633-2A> TSNVPathogenicrs81002886GRCh37Chr 13, 32950805: 32950805
1021BRCA2NM_000059.3(BRCA2): c.8636dupA (p.Asn2879Lysfs)duplicationPathogenicrs80359723GRCh37Chr 13, 32950810: 32950810
1022BRCA2NM_000059.3(BRCA2): c.8676delA (p.Arg2892Serfs)deletionPathogenicrs80359725GRCh37Chr 13, 32950850: 32950850
1023BRCA2NM_000059.3(BRCA2): c.86_87delTT (p.Leu29Glnfs)deletionPathogenicrs80359722GRCh37Chr 13, 32893232: 32893233
1024BRCA2NM_000059.3(BRCA2): c.8713_8716delTATG (p.Tyr2905Lysfs)deletionPathogenicrs80359726GRCh37Chr 13, 32950887: 32950890
1025BRCA2NM_000059.3(BRCA2): c.8717_8718delAA (p.Glu2906Glyfs)deletionPathogenicrs397508003GRCh37Chr 13, 32950891: 32950892
1026BRCA2NM_000059.3(BRCA2): c.8730delT (p.Asn2910Lysfs)deletionPathogenicrs397508004GRCh37Chr 13, 32950904: 32950904
1027BRCA2NM_000059.3(BRCA2): c.8754+1G> ASNVPathogenicrs397508006GRCh37Chr 13, 32950929: 32950929
1028BRCA2NM_000059.3(BRCA2): c.8754G> A (p.Glu2918=)SNVLikely pathogenic, Pathogenicrs80359803GRCh37Chr 13, 32950928: 32950928
1029BRCA2NM_000059.3(BRCA2): c.8756delG (p.Gly2919Valfs)deletionPathogenicrs80359728GRCh37Chr 13, 32953455: 32953455
1030BRCA2NM_000059.3(BRCA2): c.8773C> T (p.Gln2925Ter)SNVPathogenicrs80359134GRCh37Chr 13, 32953472: 32953472
1031BRCA2NM_000059.3(BRCA2): c.8789delA (p.Asn2930Ilefs)deletionPathogenicrs80359729GRCh37Chr 13, 32953488: 32953488
1032BRCA2NM_000059.3(BRCA2): c.880G> T (p.Glu294Ter)SNVPathogenicrs397508009GRCh37Chr 13, 32906495: 32906495
1033BRCA2NM_000059.3(BRCA2): c.8817_8820delGAAA (p.Lys2939Asnfs)deletionPathogenicrs397508010GRCh37Chr 13, 32953516: 32953519
1034BRCA2NM_000059.3(BRCA2): c.8821C> T (p.Gln2941Ter)SNVPathogenicrs397508012GRCh37Chr 13, 32953520: 32953520
1035BRCA2NM_000059.3(BRCA2): c.8827_8828insG (p.Gln2943Argfs)insertionPathogenicrs397508013GRCh37Chr 13, 32953526: 32953527
1036BRCA2NM_000059.3(BRCA2): c.8848_8851delAAGG (p.Lys2950Profs)deletionPathogenicrs397508015GRCh37Chr 13, 32953547: 32953550
1037BRCA2NM_000059.3(BRCA2): c.8848delAinsCT (p.Lys2950Leufs)indelPathogenicrs276174912GRCh37Chr 13, 32953547: 32953547
1038BRCA2NM_000059.3(BRCA2): c.8912delA (p.Lys2971Serfs)deletionPathogenicrs80359731GRCh37Chr 13, 32953611: 32953611
1039BRCA2NM_000059.3(BRCA2): c.8915delT (p.Leu2972Cysfs)deletionPathogenicrs397508019GRCh37Chr 13, 32953614: 32953614
1040BRCA2NM_000059.3(BRCA2): c.8924delT (p.Val2975Glufs)deletionPathogenicrs397508020GRCh37Chr 13, 32953623: 32953623
1041BRCA2NM_000059.3(BRCA2): c.8933C> A (p.Ser2978Ter)SNVPathogenicrs80359144GRCh37Chr 13, 32953632: 32953632
1042BRCA2NM_000059.3(BRCA2): c.8946delA (p.Asp2983Ilefs)deletionPathogenicrs397508021GRCh37Chr 13, 32953645: 32953645
1043BRCA2NM_000059.3(BRCA2): c.8953+1G> ASNVPathogenicrs81002882GRCh37Chr 13, 32953653: 32953653
1044BRCA2NM_000059.3(BRCA2): c.8954-3C> GSNVPathogenicrs81002844GRCh37Chr 13, 32953884: 32953884
1045BRCA2NM_000059.3(BRCA2): c.8961_8964delGAGT (p.Ser2988Phefs)deletionPathogenicrs80359734GRCh37Chr 13, 32953894: 32953897
1046BRCA2NM_000059.3(BRCA2): c.8978C> A (p.Ser2993Ter)SNVPathogenicrs397508025GRCh37Chr 13, 32953911: 32953911
1047BRCA2NM_000059.3(BRCA2): c.8978_8991delCATCAGATTTATAT (p.Ser2993Phefs)deletionPathogenicrs397508026GRCh37Chr 13, 32953911: 32953924
1048BRCA2NM_000059.3(BRCA2): c.897_898insC (p.Val300Argfs)insertionPathogenicrs80359735GRCh37Chr 13, 32906512: 32906513
1049BRCA2NM_000059.3(BRCA2): c.8980_8983delTCAG (p.Ser2994Ilefs)deletionPathogenicrs80359737GRCh37Chr 13, 32953913: 32953916
1050BRCA2NM_000059.3(BRCA2): c.8991T> G (p.Tyr2997Ter)SNVPathogenicrs397508028GRCh37Chr 13, 32953924: 32953924
1051BRCA2NM_000059.3(BRCA2): c.8999T> A (p.Leu3000Ter)SNVPathogenicrs80359151GRCh37Chr 13, 32953932: 32953932
1052BRCA2NM_000059.3(BRCA2): c.9016_9017delTA (p.Tyr3006Glnfs)deletionPathogenicrs80359739GRCh37Chr 13, 32953949: 32953950
1053BRCA2NM_000059.3(BRCA2): c.9018C> A (p.Tyr3006Ter)SNVPathogenicrs80359154GRCh37Chr 13, 32953951: 32953951
1054BRCA2NM_000059.3(BRCA2): c.901dupG (p.Asp301Glyfs)duplicationPathogenicrs80359738GRCh37Chr 13, 32906516: 32906516
1055BRCA2NM_000059.3(BRCA2): c.9027delT (p.His3010Ilefs)deletionPathogenicrs80359742GRCh37Chr 13, 32953960: 32953960
1056BRCA2NM_000059.3(BRCA2): c.9041C> A (p.Ser3014Ter)SNVPathogenicrs80359156GRCh37Chr 13, 32953974: 32953974
1057BRCA2NM_000059.3(BRCA2): c.9054_9055delTA (p.Ser3018Argfs)deletionPathogenicrs80359743GRCh37Chr 13, 32953987: 32953988
1058BRCA2NM_000059.3(BRCA2): c.9057delA (p.Lys3019Asnfs)deletionPathogenicrs80359744GRCh37Chr 13, 32953990: 32953990
1059BRCA2NM_000059.3(BRCA2): c.9063_9078del16 (p.Glu3021Aspfs)deletionPathogenicrs397508032GRCh37Chr 13, 32953996: 32954011
1060BRCA2NM_000059.3(BRCA2): c.9069_9076delTAACATAC (p.Asn3024Valfs)deletionPathogenicrs80359746GRCh37Chr 13, 32954002: 32954009
1061BRCA2NM_000059.3(BRCA2): c.906delC (p.Ser303Leufs)deletionPathogenicrs397508033GRCh37Chr 13, 32906521: 32906521
1062BRCA2NM_000059.3(BRCA2): c.9074_9075delTA (p.Ile3025Thrfs)deletionPathogenicrs397508034GRCh37Chr 13, 32954007: 32954008
1063BRCA2NM_000059.3(BRCA2): c.9098_9099insA (p.Gln3034Serfs)insertionPathogenicrs80359747GRCh37Chr 13, 32954031: 32954032
1064BRCA2NM_000059.3(BRCA2): c.9099_9100delTC (p.Gln3034Valfs)deletionPathogenicrs80359748GRCh37Chr 13, 32954032: 32954033
1065BRCA2NM_000059.3(BRCA2): c.9100C> T (p.Gln3034Ter)SNVPathogenicrs80359163GRCh37Chr 13, 32954033: 32954033
1066BRCA2NM_000059.3(BRCA2): c.9109C> T (p.Gln3037Ter)SNVPathogenicrs397508037GRCh37Chr 13, 32954042: 32954042
1067BRCA2NM_000059.3(BRCA2): c.9117+1G> ASNVPathogenicrs81002802GRCh37Chr 13, 32954051: 32954051
1068BRCA2NM_000059.3(BRCA2): c.9117+1G> TSNVPathogenicrs81002802GRCh37Chr 13, 32954051: 32954051
1069BRCA2NM_000059.3(BRCA2): c.9118-2A> GSNVPathogenicrs81002862GRCh37Chr 13, 32954142: 32954142
1070BRCA2NM_000059.3(BRCA2): c.9148C> T (p.Gln3050Ter)SNVPathogenicrs80359170GRCh37Chr 13, 32954174: 32954174
1071BRCA2NM_000059.3(BRCA2): c.9157delG (p.Glu3053Serfs)deletionPathogenicrs80359750GRCh37Chr 13, 32954183: 32954183
1072BRCA2NM_000059.3(BRCA2): c.9177delA (p.Lys3059Asnfs)deletionPathogenicrs80359751GRCh37Chr 13, 32954203: 32954203
1073BRCA2NM_000059.3(BRCA2): c.9182T> A (p.Leu3061Ter)SNVPathogenicrs80359175GRCh37Chr 13, 32954208: 32954208
1074BRCA2NM_000059.3(BRCA2): c.918dupT (p.Ser307Terfs)duplicationPathogenicrs397508039GRCh37Chr 13, 32906533: 32906533
1075BRCA2NM_000059.3(BRCA2): c.9207T> A (p.Cys3069Ter)SNVPathogenicrs80359183GRCh37Chr 13, 32954233: 32954233
1076BRCA2NM_000059.3(BRCA2): c.9227delG (p.Gly3076Aspfs)deletionPathogenicrs397508040GRCh37Chr 13, 32954253: 32954253
1077BRCA2NM_000059.3(BRCA2): c.9247A> T (p.Lys3083Ter)SNVPathogenicrs80359190GRCh37Chr 13, 32954273: 32954273
1078BRCA2NM_000059.3(BRCA2): c.9253delA (p.Thr3085Glnfs)deletionPathogenicrs397508041GRCh37Chr 13, 32954279: 32954279
1079BRCA2NM_000059.3(BRCA2): c.9256+1G> ASNVPathogenicrs81002883GRCh37Chr 13, 32954283: 32954283
1080BRCA2NM_000059.3(BRCA2): c.9256G> T (p.Gly3086Ter)SNVPathogenicrs80359192GRCh37Chr 13, 32954282: 32954282
1081BRCA2NM_000059.3(BRCA2): c.9269dupT (p.Val3091Argfs)duplicationPathogenicrs80359753GRCh37Chr 13, 32968838: 32968838
1082BRCA2NM_000059.3(BRCA2): c.9275_9276delAT (p.Tyr3092Phefs)deletionPathogenicrs397508043GRCh37Chr 13, 32968844: 32968845
1083BRCA2NM_000059.3(BRCA2): c.9276T> G (p.Tyr3092Ter)SNVPathogenicrs80359197GRCh37Chr 13, 32968845: 32968845
1084BRCA2NM_000059.3(BRCA2): c.9286G> T (p.Glu3096Ter)SNVPathogenicrs80359199GRCh37Chr 13, 32968855: 32968855
1085BRCA2NM_000059.3(BRCA2): c.92G> A (p.Trp31Ter)SNVPathogenicrs397508045GRCh37Chr 13, 32893238: 32893238
1086BRCA2NM_000059.3(BRCA2): c.930_931delAT (p.Cys311Phefs)deletionPathogenicrs80359755GRCh37Chr 13, 32906545: 32906546
1087BRCA2NM_000059.3(BRCA2): c.9310_9311delAA (p.Lys3104Valfs)deletionPathogenicrs80359756GRCh37Chr 13, 32968879: 32968880
1088BRCA2NM_000059.3(BRCA2): c.9317G> A (p.Trp3106Ter)SNVPathogenicrs80359205GRCh37Chr 13, 32968886: 32968886
1089BRCA2NM_000059.3(BRCA2): c.9331G> T (p.Glu3111Ter)SNVPathogenicrs397508047GRCh37Chr 13, 32968900: 32968900
1090BRCA2NM_000059.3(BRCA2): c.9356T> G (p.Leu3119Ter)SNVPathogenicrs80359207GRCh37Chr 13, 32968925: 32968925
1091BRCA2NM_000059.3(BRCA2): c.9360delT (p.Ile3120Metfs)deletionPathogenicrs80359757GRCh37Chr 13, 32968929: 32968929
1092BRCA2NM_000059.3(BRCA2): c.9393delC (p.Lys3132Asnfs)deletionPathogenicrs397508049GRCh37Chr 13, 32968962: 32968962
1093BRCA2NM_000059.3(BRCA2): c.93G> A (p.Trp31Ter)SNVPathogenicrs80359214GRCh37Chr 13, 32893239: 32893239
1094BRCA2NM_000059.3(BRCA2): c.9408delT (p.Thr3137Leufs)deletionPathogenicrs80359761GRCh37Chr 13, 32968977: 32968977
1095BRCA2NM_000059.3(BRCA2): c.9430delT (p.Ser3144Leufs)deletionPathogenicrs397508050GRCh37Chr 13, 32968999: 32968999
1096BRCA2NM_000059.3(BRCA2): c.9455_9456delAG (p.Glu3152Glyfs)deletionPathogenicrs80359764GRCh37Chr 13, 32969024: 32969025
1097BRCA2NM_000059.3(BRCA2): c.9458delG (p.Gly3153Alafs)deletionPathogenicrs397508052GRCh37Chr 13, 32969027: 32969027
1098BRCA2NM_000059.3(BRCA2): c.9463_9467delTTTCAinsGAATGATC (p.Phe3155_Ile3418delinsGlu)indelPathogenicrs397508053GRCh37Chr 13, 32969032: 32969036
1099BRCA2NM_000059.3(BRCA2): c.9466C> T (p.Gln3156Ter)SNVPathogenicrs276174925GRCh37Chr 13, 32969035: 32969035
1100BRCA2NM_000059.3(BRCA2): c.9466delC (p.Gln3156Lysfs)deletionPathogenicrs80359766GRCh37Chr 13, 32969035: 32969035
1101BRCA2NM_000059.3(BRCA2): c.9474delA (p.Phe3159Serfs)deletionPathogenicrs397508054GRCh37Chr 13, 32969043: 32969043
1102BRCA2NM_000059.3(BRCA2): c.9481A> T (p.Lys3161Ter)SNVPathogenicrs80359222GRCh37Chr 13, 32969050: 32969050
1103BRCA2NM_000059.3(BRCA2): c.9498delT (p.Glu3167Argfs)deletionPathogenicrs397508055GRCh37Chr 13, 32969067: 32969067
1104BRCA2NM_000059.3(BRCA2): c.9501+1G> ASNVPathogenicrs397508058GRCh37Chr 13, 32969071: 32969071
1105BRCA2NM_000059.3(BRCA2): c.9501G> A (p.Glu3167=)SNVPathogenicrs80359808GRCh37Chr 13, 32969070: 32969070
1106BRCA2NM_000059.3(BRCA2): c.9502-2A> CSNVLikely pathogenic, Pathogenicrs81002868GRCh37Chr 13, 32971033: 32971033
1107BRCA2NM_000059.3(BRCA2): c.9507delT (p.Ile3169Metfs)deletionPathogenicrs80359767GRCh37Chr 13, 32971040: 32971040
1108BRCA2NM_000059.3(BRCA2): c.9513_9516delACTT (p.Leu3172Alafs)deletionPathogenicrs80359769GRCh37Chr 13, 32971046: 32971049
1109BRCA2NM_000059.3(BRCA2): c.952A> T (p.Lys318Ter)SNVPathogenicrs397508060GRCh37Chr 13, 32906567: 32906567
1110BRCA2NM_000059.3(BRCA2): c.9537dupG (p.Leu3180Alafs)duplicationPathogenicrs397508061GRCh37Chr 13, 32971070: 32971070
1111BRCA2NM_000059.3(BRCA2): c.9541_9554delATGCATATACTGCA (p.Met3181Cysfs)deletionPathogenicrs397508062GRCh37Chr 13, 32971074: 32971087
1112BRCA2NM_000059.3(BRCA2): c.9572G> A (p.Trp3191Ter)SNVPathogenicrs397508063GRCh37Chr 13, 32971105: 32971105
1113BRCA2NM_000059.3(BRCA2): c.961C> T (p.Gln321Ter)SNVPathogenicrs80359234GRCh37Chr 13, 32906576: 32906576
1114BRCA2NM_000059.3(BRCA2): c.9649-2A> GSNVPathogenicrs81002895GRCh37Chr 13, 32972297: 32972297
1115BRCA2NM_000059.3(BRCA2): c.9666delT (p.Cys3222Trpfs)deletionPathogenicrs80359772GRCh37Chr 13, 32972316: 32972316
1116BRCA2NM_000059.3(BRCA2): c.9676delT (p.Tyr3226Ilefs)deletionPathogenicrs80359774GRCh37Chr 13, 32972326: 32972326
1117BRCA2NM_000059.3(BRCA2): c.97G> T (p.Glu33Ter)SNVPathogenicrs397508065GRCh37Chr 13, 32893243: 32893243
1118BRCA2NM_000059.3(BRCA2): c.9868delG (p.Val3290Phefs)deletionPathogenicrs80359776GRCh37Chr 13, 32972518: 32972518
1119BRCA2NM_000059.3(BRCA2): c.9883C> T (p.Gln3295Ter)SNVPathogenicrs80359247GRCh37Chr 13, 32972533: 32972533
1120BRCA2NM_000059.3(BRCA2): c.9925G> T (p.Glu3309Ter)SNVPathogenicrs80359251GRCh37Chr 13, 32972575: 32972575
1121BRCA2NM_000059.3(BRCA2): c.993_994delAA (p.Lys331Asnfs)deletionPathogenicrs80359777GRCh37Chr 13, 32906608: 32906609
1122BRCA2NM_000059.3(BRCA2): c.994delA (p.Ile332Phefs)deletionPathogenicrs80359778GRCh37Chr 13, 32906609: 32906609
1123BRCA2NM_000059.3(BRCA2): c.994dupA (p.Ile332Asnfs)duplicationPathogenicrs397508066GRCh37Chr 13, 32906609: 32906609
1124BRCA1NM_007294.3(BRCA1): c.1008dupA (p.Glu337Argfs)duplicationPathogenicrs67284603GRCh37Chr 17, 41246540: 41246540
1125BRCA1NM_007294.3(BRCA1): c.1012A> T (p.Lys338Ter)SNVPathogenicrs397508826GRCh37Chr 17, 41246536: 41246536
1126BRCA1NM_007294.3(BRCA1): c.101delC (p.Pro34Leufs)deletionPathogenicrs80357750GRCh37Chr 17, 41267776: 41267776
1127BRCA1NM_007294.3(BRCA1): c.1039_1040delCT (p.Leu347Valfs)deletionPathogenicrs397508827GRCh37Chr 17, 41246508: 41246509
1128BRCA1NM_007294.3(BRCA1): c.1045G> T (p.Glu349Ter)SNVPathogenicrs80357338GRCh37Chr 17, 41246503: 41246503
1129BRCA1NM_007294.3(BRCA1): c.1054G> T (p.Glu352Ter)SNVPathogenicrs80357472GRCh37Chr 17, 41246494: 41246494
1130BRCA1NM_007294.3(BRCA1): c.1058G> A (p.Trp353Ter)SNVPathogenicrs80356908GRCh37Chr 17, 41246490: 41246490
1131BRCA1NM_007294.3(BRCA1): c.1059G> A (p.Trp353Ter)SNVPathogenicrs80356935GRCh37Chr 17, 41246489: 41246489
1132BRCA1NM_007294.3(BRCA1): c.1066C> T (p.Gln356Ter)SNVPathogenicrs80357215GRCh37Chr 17, 41246482: 41246482
1133BRCA1NM_007294.3(BRCA1): c.1067delA (p.Gln356Argfs)deletionPathogenicrs80357796GRCh37Chr 17, 41246481: 41246481
1134BRCA1NM_007294.3(BRCA1): c.1068_1077delGAAACTGCCA (p.Gln356Hisfs)deletionPathogenicrs397508830GRCh37Chr 17, 41246471: 41246480
1135BRCA1NM_007294.3(BRCA1): c.1072delC (p.Leu358Cysfs)deletionPathogenicrs80357836GRCh37Chr 17, 41246476: 41246476
1136BRCA1NM_007294.3(BRCA1): c.1082C> G (p.Ser361Ter)SNVPathogenicrs397508833GRCh37Chr 17, 41246466: 41246466
1137BRCA1NM_007294.3(BRCA1): c.1082_1092delCAGAGAATCCT (p.Ser361Terfs)deletionPathogenicrs80359880GRCh37Chr 17, 41246456: 41246466
1138BRCA1NM_007294.3(BRCA1): c.1086_1087delGA (p.Asn363Serfs)deletionPathogenicrs80357897GRCh37Chr 17, 41246461: 41246462
1139BRCA1NM_007294.3(BRCA1): c.1088delA (p.Asn363Ilefs)deletionPathogenicrs80357954GRCh37Chr 17, 41246460: 41246460
1140BRCA1NM_007294.3(BRCA1): c.1091delC (p.Pro364Leufs)deletionPathogenicrs397508834GRCh37Chr 17, 41246457: 41246457
1141BRCA1NM_007294.3(BRCA1): c.1102G> T (p.Glu368Ter)SNVPathogenicrs80357139GRCh37Chr 17, 41246446: 41246446
1142BRCA1NM_007294.3(BRCA1): c.110C> A (p.Thr37Lys)SNVPathogenicrs80356880GRCh37Chr 17, 41267767: 41267767
1143BRCA1NM_007294.3(BRCA1): c.1115G> A (p.Trp372Ter)SNVPathogenicrs397508838GRCh37Chr 17, 41246433: 41246433
1144BRCA1NM_007294.3(BRCA1): c.1116G> A (p.Trp372Ter)SNVPathogenicrs80357468GRCh37Chr 17, 41246432: 41246432
1145BRCA1NM_007294.3(BRCA1): c.1121_1123delCACinsT (p.Thr374Ilefs)indelPathogenicrs273897652GRCh37Chr 17, 41246425: 41246427
1146BRCA1NM_007294.3(BRCA1): c.1127delA (p.Asn376Ilefs)deletionPathogenicrs80357821GRCh37Chr 17, 41246421: 41246421
1147BRCA1NM_007294.3(BRCA1): c.1138C> T (p.Gln380Ter)SNVPathogenicrs397508840GRCh37Chr 17, 41246410: 41246410
1148BRCA1NM_007294.3(BRCA1): c.1141A> T (p.Lys381Ter)SNVPathogenicrs80357385GRCh37Chr 17, 41246407: 41246407
1149BRCA1NM_007294.3(BRCA1): c.1152dupG (p.Trp385Valfs)duplicationPathogenicrs397508841GRCh37Chr 17, 41246396: 41246396
1150BRCA1NM_007294.3(BRCA1): c.115T> C (p.Cys39Arg)SNVPathogenicrs80357164GRCh37Chr 17, 41267762: 41267762
1151BRCA1NM_007294.3(BRCA1): c.115T> G (p.Cys39Gly)SNVPathogenicrs80357164GRCh37Chr 17, 41267762: 41267762
1152BRCA1NM_007294.3(BRCA1): c.1165delA (p.Ser389Valfs)deletionPathogenicrs80357985GRCh37Chr 17, 41246383: 41246383
1153BRCA1NM_007294.3(BRCA1): c.1166delG (p.Ser389Metfs)deletionPathogenicrs273897653GRCh37Chr 17, 41246382: 41246382
1154BRCA1NM_007294.3(BRCA1): c.117_118delTG (p.Cys39Terfs)deletionPathogenicrs80357972GRCh37Chr 17, 41267759: 41267760
1155BRCA1NM_007294.3(BRCA1): c.1193C> G (p.Ser398Ter)SNVPathogenicrs80357068GRCh37Chr 17, 41246355: 41246355
1156BRCA1NM_007294.3(BRCA1): c.1204G> T (p.Glu402Ter)SNVPathogenicrs273897655GRCh37Chr 17, 41246344: 41246344
1157BRCA1NM_007294.3(BRCA1): c.1214C> A (p.Ser405Ter)SNVPathogenicrs80357481GRCh37Chr 17, 41246334: 41246334
1158BRCA1NM_007294.3(BRCA1): c.122A> G (p.His41Arg)SNVPathogenicrs80357276GRCh37Chr 17, 41267755: 41267755
1159BRCA1NM_007294.3(BRCA1): c.1232_1233delAT (p.Asp411Glyfs)deletionPathogenicrs397508848GRCh37Chr 17, 41246315: 41246316
1160BRCA1NM_007294.3(BRCA1): c.1240_1246delGACGTTC (p.Asp414Terfs)deletionPathogenicrs80357964GRCh37Chr 17, 41246302: 41246308
1161BRCA1NM_007294.3(BRCA1): c.1241dupA (p.Asp414Glufs)duplicationPathogenicrs80357514GRCh37Chr 17, 41246307: 41246307
1162BRCA1NM_007294.3(BRCA1): c.124delA (p.Ile42Tyrfs)deletionPathogenicrs80357943GRCh37Chr 17, 41267753: 41267753
1163BRCA1NM_007294.3(BRCA1): c.1252G> T (p.Glu418Ter)SNVPathogenicrs80357083GRCh37Chr 17, 41246296: 41246296
1164BRCA1NM_007294.3(BRCA1): c.1255delG (p.Val419Terfs)deletionPathogenicrs80357535GRCh37Chr 17, 41246293: 41246293
1165BRCA1NM_007294.3(BRCA1): c.1265dupA (p.Tyr422Terfs)duplicationPathogenicrs80357809GRCh37Chr 17, 41246283: 41246283
1166BRCA1NM_007294.3(BRCA1): c.1266T> G (p.Tyr422Ter)SNVPathogenicrs80357417GRCh37Chr 17, 41246282: 41246282
1167BRCA1NM_007294.3(BRCA1): c.1276delT (p.Ser426Glnfs)deletionPathogenicrs80357766GRCh37Chr 17, 41246272: 41246272
1168BRCA1NM_007294.3(BRCA1): c.1287dupA (p.Asp430Argfs)duplicationPathogenicrs80357576GRCh37Chr 17, 41246261: 41246261
1169BRCA1NM_007294.3(BRCA1): c.1292T> G (p.Leu431Ter)SNVPathogenicrs80357346GRCh37Chr 17, 41246256: 41246256
1170BRCA1NM_007294.3(BRCA1): c.1292dupT (p.Leu431Phefs)duplicationPathogenicrs80357528GRCh37Chr 17, 41246256: 41246256
1171BRCA1NM_007294.3(BRCA1): c.1297delG (p.Ala433Profs)deletionPathogenicrs80357794GRCh37Chr 17, 41246251: 41246251
1172BRCA1NM_007294.3(BRCA1): c.130T> A (p.Cys44Ser)SNVPathogenicrs80357327GRCh37Chr 17, 41267747: 41267747
1173BRCA1NM_007294.3(BRCA1): c.130delT (p.Cys44Alafs)deletionPathogenicrs80357951GRCh37Chr 17, 41267747: 41267747
1174BRCA1NM_007294.3(BRCA1): c.1319delT (p.Leu440Terfs)deletionPathogenicrs80357683GRCh37Chr 17, 41246229: 41246229
1175BRCA1NM_007294.3(BRCA1): c.131G> A (p.Cys44Tyr)SNVPathogenicrs80357446GRCh37Chr 17, 41267746: 41267746
1176BRCA1NM_007294.3(BRCA1): c.131G> T (p.Cys44Phe)SNVLikely pathogenic, Pathogenicrs80357446GRCh37Chr 17, 41267746: 41267746
1177BRCA1NM_007294.3(BRCA1): c.1323_1324delAT (p.Ile441Metfs)deletionPathogenicrs80357570GRCh37Chr 17, 41246224: 41246225
1178BRCA1NM_007294.3(BRCA1): c.1326T> A (p.Cys442Ter)SNVPathogenicrs397508854GRCh37Chr 17, 41246222: 41246222
1179BRCA1NM_007294.3(BRCA1): c.1333G> T (p.Glu445Ter)SNVPathogenicrs80356915GRCh37Chr 17, 41246215: 41246215
1180BRCA1NM_007294.3(BRCA1): c.1335_1336delAA (p.Arg446Serfs)deletionPathogenicrs80357978GRCh37Chr 17, 41246212: 41246213
1181BRCA1NM_007294.3(BRCA1): c.133_134+3delAAGTAinsTindelPathogenicrs397508856GRCh37Chr 17, 41267740: 41267744
1182BRCA1NM_007294.3(BRCA1): c.133_134delAA (p.Lys45Ilefs)deletionPathogenicrs397508857GRCh37Chr 17, 41267743: 41267744
1183BRCA1NM_007294.3(BRCA1): c.134+1G> TSNVPathogenicrs80358043GRCh37Chr 17, 41267742: 41267742
1184BRCA1NM_007294.3(BRCA1): c.134+2T> GSNVPathogenicrs80358131GRCh37Chr 17, 41267741: 41267741
1185BRCA1NM_007294.3(BRCA1): c.134+3_134+6delAAGTdeletionPathogenicrs397508858GRCh37Chr 17, 41267737: 41267740
1186BRCA1NM_007294.3(BRCA1): c.135-1G> CSNVPathogenicrs80358158GRCh37Chr 17, 41258551: 41258551
1187BRCA1NM_007294.3(BRCA1): c.1352C> A (p.Ser451Ter)SNVPathogenicrs80356891GRCh37Chr 17, 41246196: 41246196
1188BRCA1NM_007294.3(BRCA1): c.1352C> G (p.Ser451Ter)SNVPathogenicrs80356891GRCh37Chr 17, 41246196: 41246196
1189BRCA1NM_007294.3(BRCA1): c.1371delA (p.Asp458Thrfs)deletionPathogenicrs397508861GRCh37Chr 17, 41246177: 41246177
1190BRCA1NM_007294.3(BRCA1): c.1374delC (p.Asp458Glufs)deletionPathogenicrs397508862GRCh37Chr 17, 41246174: 41246174
1191BRCA1NM_007294.3(BRCA1): c.1380dupA (p.Phe461Ilefs)duplicationPathogenicrs80357714GRCh37Chr 17, 41246168: 41246168
1192BRCA1NM_007294.3(BRCA1): c.1383delT (p.Phe461Leufs)deletionPathogenicrs80357879GRCh37Chr 17, 41246165: 41246165
1193BRCA1NM_007294.3(BRCA1): c.1386delG (p.Thr464Profs)deletionPathogenicrs80357722GRCh37Chr 17, 41246162: 41246162
1194BRCA1NM_007294.3(BRCA1): c.1386dupG (p.Lys463Glufs)duplicationPathogenicrs397508865GRCh37Chr 17, 41246162: 41246162
1195BRCA1NM_007294.3(BRCA1): c.1387_1390delAAAAinsGAAAG (p.Lys463Glufs)indelPathogenicrs397508866GRCh37Chr 17, 41246158: 41246161
1196BRCA1NM_007294.3(BRCA1): c.1390delA (p.Thr464Profs)deletionPathogenicrs80357770GRCh37Chr 17, 41246158: 41246158
1197BRCA1NM_007294.3(BRCA1): c.1392delC (p.Tyr465Ilefs)deletionPathogenicrs397508868GRCh37Chr 17, 41246156: 41246156
1198BRCA1NM_007294.3(BRCA1): c.1399A> T (p.Lys467Ter)SNVPathogenicrs80357279GRCh37Chr 17, 41246149: 41246149
1199BRCA1NM_007294.3(BRCA1): c.1403delA (p.Lys468Argfs)deletionPathogenicrs397508870GRCh37Chr 17, 41246145: 41246145
1200BRCA1NM_007294.3(BRCA1): c.1405delG (p.Ala469Glnfs)deletionPathogenicrs397508871GRCh37Chr 17, 41246143: 41246143
1201BRCA1NM_007294.3(BRCA1): c.140G> A (p.Cys47Tyr)SNVPathogenicrs80357150GRCh37Chr 17, 41258545: 41258545
1202BRCA1NM_007294.3(BRCA1): c.140G> T (p.Cys47Phe)SNVLikely pathogenic, Pathogenicrs80357150GRCh37Chr 17, 41258545: 41258545
1203BRCA1NM_007294.3(BRCA1): c.1421T> G (p.Leu474Ter)SNVPathogenicrs80357490GRCh37Chr 17, 41246127: 41246127
1204BRCA1NM_007294.3(BRCA1): c.1444delA (p.Ile482Leufs)deletionPathogenicrs80357648GRCh37Chr 17, 41246104: 41246104
1205BRCA1NM_007294.3(BRCA1): c.144delG (p.Met48Ilefs)deletionPathogenicrs80357682GRCh37Chr 17, 41258541: 41258541
1206BRCA1NM_007294.3(BRCA1): c.1450G> T (p.Gly484Ter)SNVPathogenicrs80357304GRCh37Chr 17, 41246098: 41246098
1207BRCA1NM_007294.3(BRCA1): c.1465G> T (p.Glu489Ter)SNVPathogenicrs80357167GRCh37Chr 17, 41246083: 41246083
1208BRCA1NM_007294.3(BRCA1): c.1471C> T (p.Gln491Ter)SNVPathogenicrs62625303GRCh37Chr 17, 41246077: 41246077
1209BRCA1NM_007294.3(BRCA1): c.1483_1498del16 (p.Glu495Ilefs)deletionPathogenicrs397508872GRCh37Chr 17, 41246050: 41246065
1210BRCA1NM_007294.3(BRCA1): c.1492delC (p.Leu498Serfs)deletionPathogenicrs80357527GRCh37Chr 17, 41246056: 41246056
1211BRCA1NM_007294.3(BRCA1): c.1499delA (p.Asn500Ilefs)deletionPathogenicrs397508874GRCh37Chr 17, 41246049: 41246049
1212BRCA1NM_007294.3(BRCA1): c.1508delA (p.Lys503Serfs)deletionPathogenicrs80357506GRCh37Chr 17, 41246040: 41246040
1213BRCA1NM_007294.3(BRCA1): c.150delA (p.Lys50Asnfs)deletionPathogenicrs273897662GRCh37Chr 17, 41258535: 41258535
1214BRCA1NM_007294.3(BRCA1): c.1511dupG (p.Lys505Terfs)duplicationPathogenicrs80357817GRCh37Chr 17, 41246037: 41246037
1215BRCA1NM_007294.3(BRCA1): c.1513A> T (p.Lys505Ter)SNVPathogenicrs397508877GRCh37Chr 17, 41246035: 41246035
1216BRCA1NM_007294.3(BRCA1): c.1513_1514insT (p.Lys505Ilefs)insertionPathogenicrs397508878GRCh37Chr 17, 41246034: 41246035
1217BRCA1NM_007294.3(BRCA1): c.1523delC (p.Pro508Leufs)deletionPathogenicrs80357782GRCh37Chr 17, 41246025: 41246025
1218BRCA1NM_007294.3(BRCA1): c.1529C> G (p.Ser510Ter)SNVPathogenicrs80357427GRCh37Chr 17, 41246019: 41246019
1219BRCA1NM_007294.3(BRCA1): c.1530delA (p.Gly511Alafs)deletionPathogenicrs80357735GRCh37Chr 17, 41246018: 41246018
1220BRCA1NM_007294.3(BRCA1): c.1576C> T (p.Gln526Ter)SNVPathogenicrs80356984GRCh37Chr 17, 41245972: 41245972
1221BRCA1NM_007294.3(BRCA1): c.1583_1589delCTCCTGA (p.Thr528Lysfs)deletionPathogenicrs80357613GRCh37Chr 17, 41245959: 41245965
1222BRCA1NM_007294.3(BRCA1): c.1600C> T (p.Gln534Ter)SNVPathogenicrs142074233GRCh37Chr 17, 41245948: 41245948
1223BRCA1NM_007294.3(BRCA1): c.1601dupA (p.Thr536Asnfs)duplicationPathogenicrs397508889GRCh37Chr 17, 41245947: 41245947
1224BRCA1NM_007294.3(BRCA1): c.1608_1611delTAAC (p.Asn537Lysfs)deletionPathogenicrs80357698GRCh37Chr 17, 41245937: 41245940
1225BRCA1NM_007294.3(BRCA1): c.160C> T (p.Gln54Ter)SNVPathogenicrs80356864GRCh37Chr 17, 41258525: 41258525
1226BRCA1NM_007294.3(BRCA1): c.1612C> T (p.Gln538Ter)SNVPathogenicrs80356893GRCh37Chr 17, 41245936: 41245936
1227BRCA1NM_007294.3(BRCA1): c.1621C> T (p.Gln541Ter)SNVPathogenicrs80356904GRCh37Chr 17, 41245927: 41245927
1228BRCA1NM_007294.3(BRCA1): c.1623dupG (p.Asn542Glufs)duplicationPathogenicrs397508891GRCh37Chr 17, 41245925: 41245925
1229BRCA1NM_007294.3(BRCA1): c.1630C> T (p.Gln544Ter)SNVPathogenicrs80356952GRCh37Chr 17, 41245918: 41245918
1230BRCA1NM_007294.3(BRCA1): c.1636_1654del19 (p.Met546Valfs)deletionPathogenicrs80359881GRCh37Chr 17, 41245894: 41245912
1231BRCA1NM_007294.3(BRCA1): c.1649delA (p.Asn550Ilefs)deletionPathogenicrs80357619GRCh37Chr 17, 41245899: 41245899
1232BRCA1NM_007294.3(BRCA1): c.1713_1717delAGAAT (p.Glu572Thrfs)deletionPathogenicrs80357640GRCh37Chr 17, 41245831: 41245835
1233BRCA1NM_007294.3(BRCA1): c.1716delA (p.Glu572Aspfs)deletionPathogenicrs397508900GRCh37Chr 17, 41245832: 41245832
1234BRCA1NM_007294.3(BRCA1): c.1729G> T (p.Glu577Ter)SNVPathogenicrs397508903GRCh37Chr 17, 41245819: 41245819
1235BRCA1NM_007294.3(BRCA1): c.1729_1730delGA (p.Glu577Ilefs)deletionPathogenicrs80357834GRCh37Chr 17, 41245818: 41245819
1236BRCA1NM_007294.3(BRCA1): c.1747A> T (p.Lys583Ter)SNVPathogenicrs80356928GRCh37Chr 17, 41245801: 41245801
1237BRCA1NM_007294.3(BRCA1): c.1757delC (p.Pro586Leufs)deletionPathogenicrs80357723GRCh37Chr 17, 41245791: 41245791
1238BRCA1NM_007294.3(BRCA1): c.1772delT (p.Ile591Lysfs)deletionPathogenicrs80357901GRCh37Chr 17, 41245776: 41245776
1239BRCA1NM_007294.3(BRCA1): c.1789G> T (p.Glu597Ter)SNVPathogenicrs55650082GRCh37Chr 17, 41245759: 41245759
1240BRCA1NM_007294.3(BRCA1): c.178C> T (p.Gln60Ter)SNVPathogenicrs80357471GRCh37Chr 17, 41258507: 41258507
1241BRCA1NM_007294.3(BRCA1): c.1793T> G (p.Leu598Ter)SNVPathogenicrs80357118GRCh37Chr 17, 41245755: 41245755
1242BRCA1NM_007294.3(BRCA1): c.179delA (p.Gln60Argfs)deletionPathogenicrs80357591GRCh37Chr 17, 41258506: 41258506
1243BRCA1NM_007294.3(BRCA1): c.1805delA (p.Asn602Ilefs)deletionPathogenicrs397508908GRCh37Chr 17, 41245743: 41245743
1244BRCA1NM_007294.3(BRCA1): c.1808C> G (p.Ser603Ter)SNVPathogenicrs397508909GRCh37Chr 17, 41245740: 41245740
1245BRCA1NM_007294.3(BRCA1): c.1819A> T (p.Lys607Ter)SNVPathogenicrs80357220GRCh37Chr 17, 41245729: 41245729
1246BRCA1NM_007294.3(BRCA1): c.181T> A (p.Cys61Ser)SNVPathogenicrs28897672GRCh37Chr 17, 41258504: 41258504
1247BRCA1NM_007294.3(BRCA1): c.1823_1826delAGAA (p.Lys608Ilefs)deletionPathogenicrs80357585GRCh37Chr 17, 41245722: 41245725
1248BRCA1NM_007294.3(BRCA1): c.1823delA (p.Lys608Argfs)deletionPathogenicrs397508911GRCh37Chr 17, 41245725: 41245725
1249BRCA1NM_007294.3(BRCA1): c.182_183delGT (p.Cys61Serfs)deletionPathogenicrs397508912GRCh37Chr 17, 41258502: 41258503
1250BRCA1NM_007294.3(BRCA1): c.1831delC (p.Leu611Terfs)deletionPathogenicrs397508913GRCh37Chr 17, 41245717: 41245717
1251BRCA1NM_007294.3(BRCA1): c.1837delA (p.Arg613Glyfs)deletionPathogenicrs80357652GRCh37Chr 17, 41245711: 41245711
1252BRCA1NM_007294.3(BRCA1): c.1840A> T (p.Lys614Ter)SNVPathogenicrs80357282GRCh37Chr 17, 41245708: 41245708
1253BRCA1NM_007294.3(BRCA1): c.1870G> T (p.Glu624Ter)SNVPathogenicrs80356950GRCh37Chr 17, 41245678: 41245678
1254BRCA1NM_007294.3(BRCA1): c.188T> A (p.Leu63Ter)SNVPathogenicrs80357086GRCh37Chr 17, 41258497: 41258497
1255BRCA1NM_007294.3(BRCA1): c.1898delC (p.Pro633Hisfs)deletionPathogenicrs80357851GRCh37Chr 17, 41245650: 41245650
1256BRCA1NM_007294.3(BRCA1): c.189dupA (p.Cys64Metfs)duplicationPathogenicrs273897665GRCh37Chr 17, 41258496: 41258496
1257BRCA1NM_007294.3(BRCA1): c.1906delT (p.Cys636Valfs)deletionPathogenicrs397508916GRCh37Chr 17, 41245642: 41245642
1258BRCA1NM_007294.3(BRCA1): c.1912G> T (p.Glu638Ter)SNVPathogenicrs80357005GRCh37Chr 17, 41245636: 41245636
1259BRCA1NM_007294.3(BRCA1): c.1912delG (p.Glu638Asnfs)deletionPathogenicrs80357933GRCh37Chr 17, 41245636: 41245636
1260BRCA1NM_007294.3(BRCA1): c.1916T> A (p.Leu639Ter)SNVPathogenicrs80357267GRCh37Chr 17, 41245632: 41245632
1261BRCA1NM_007294.3(BRCA1): c.1936delA (p.Ser646Alafs)deletionPathogenicrs397508919GRCh37Chr 17, 41245612: 41245612
1262BRCA1NM_007294.3(BRCA1): c.1938_1947delCAGTGAAGAG (p.Ser646Argfs)deletionPathogenicrs397508920GRCh37Chr 17, 41245601: 41245610
1263BRCA1NM_007294.3(BRCA1): c.1945G> T (p.Glu649Ter)SNVPathogenicrs80356907GRCh37Chr 17, 41245603: 41245603
1264BRCA1NM_007294.3(BRCA1): c.1949_1950delTA (p.Ile650Lysfs)deletionPathogenicrs397508921GRCh37Chr 17, 41245598: 41245599
1265BRCA1NM_007294.3(BRCA1): c.1952delA (p.Lys651Argfs)deletionPathogenicrs397508922GRCh37Chr 17, 41245596: 41245596
1266BRCA1NM_007294.3(BRCA1): c.1952dupA (p.Lys652Glufs)duplicationPathogenicrs80357885GRCh37Chr 17, 41245596: 41245596
1267BRCA1NM_007294.3(BRCA1): c.1953dupG (p.Lys652Glufs)duplicationPathogenicrs80357753GRCh37Chr 17, 41245595: 41245595
1268BRCA1NM_007294.3(BRCA1): c.1958_1961delAAAA (p.Lys653Serfs)deletionPathogenicrs397508923GRCh37Chr 17, 41245587: 41245590
1269BRCA1NM_007294.3(BRCA1): c.195delG (p.Asn66Metfs)deletionPathogenicrs80357869GRCh37Chr 17, 41258490: 41258490
1270BRCA1NM_007294.3(BRCA1): c.1960_1961delAA (p.Lys654Valfs)deletionPathogenicrs80357643GRCh37Chr 17, 41245587: 41245588
1271BRCA1NM_007294.3(BRCA1): c.1963_1964insG (p.Tyr655Terfs)insertionPathogenicrs397508924GRCh37Chr 17, 41245584: 41245585
1272BRCA1NM_007294.3(BRCA1): c.1969C> T (p.Gln657Ter)SNVPathogenicrs397508926GRCh37Chr 17, 41245579: 41245579
1273BRCA1NM_007294.3(BRCA1): c.1996delC (p.Leu666Tyrfs)deletionPathogenicrs80357922GRCh37Chr 17, 41245552: 41245552
1274BRCA1NM_007294.3(BRCA1): c.1999C> T (p.Gln667Ter)SNVPathogenicrs80356889GRCh37Chr 17, 41245549: 41245549
1275BRCA1NM_007294.3(BRCA1): c.1A> G (p.Met1Val)SNVPathogenicrs80357287GRCh37Chr 17, 41276113: 41276113
1276BRCA1NM_007294.3(BRCA1): c.2014A> T (p.Lys672Ter)SNVPathogenicrs397508929GRCh37Chr 17, 41245534: 41245534
1277BRCA1NM_007294.3(BRCA1): c.2017G> T (p.Glu673Ter)SNVPathogenicrs80357391GRCh37Chr 17, 41245531: 41245531
1278BRCA1NM_007294.3(BRCA1): c.2017delG (p.Glu673Asnfs)deletionPathogenicrs80357638GRCh37Chr 17, 41245531: 41245531
1279BRCA1NM_007294.3(BRCA1): c.2037delGinsCC (p.Lys679Asnfs)indelPathogenicrs397508932GRCh37Chr 17, 41245511: 41245511
1280BRCA1NM_007294.3(BRCA1): c.2059C> T (p.Gln687Ter)SNVPathogenicrs273898674GRCh37Chr 17, 41245489: 41245489
1281BRCA1NM_007294.3(BRCA1): c.2063_2066delCAAG (p.Thr688Ilefs)deletionPathogenicrs397508935GRCh37Chr 17, 41245482: 41245485
1282BRCA1NM_007294.3(BRCA1): c.2074delC (p.His692Metfs)deletionPathogenicrs80357554GRCh37Chr 17, 41245474: 41245474
1283BRCA1NM_007294.3(BRCA1): c.2079_2080delCA (p.Asp693Glufs)deletionPathogenicrs80357773GRCh37Chr 17, 41245468: 41245469
1284BRCA1NM_007294.3(BRCA1): c.2105T> G (p.Leu702Ter)SNVPathogenicrs80357298GRCh37Chr 17, 41245443: 41245443
1285BRCA1NM_007294.3(BRCA1): c.212+1G> CSNVPathogenicrs80358042GRCh37Chr 17, 41258472: 41258472
1286BRCA1NM_007294.3(BRCA1): c.212+1G> TSNVPathogenicrs80358042GRCh37Chr 17, 41258472: 41258472
1287BRCA1NM_007294.3(BRCA1): c.212+2T> CSNVPathogenicrs80358026GRCh37Chr 17, 41258471: 41258471
1288BRCA1NM_007294.3(BRCA1): c.212+3A> GSNVPathogenicrs80358083GRCh37Chr 17, 41258470: 41258470
1289BRCA1NM_007294.3(BRCA1): c.2125_2126insA (p.Phe709Tyrfs)insertionPathogenicrs80357871GRCh37Chr 17, 41245422: 41245423
1290BRCA1NM_007294.3(BRCA1): c.2126_2127delTT (p.Phe709Tyrfs)deletionPathogenicrs397508939GRCh37Chr 17, 41245421: 41245422
1291BRCA1NM_007294.3(BRCA1): c.212G> A (p.Arg71Lys)SNVPathogenicrs80356913GRCh37Chr 17, 41258473: 41258473
1292BRCA1NM_007294.3(BRCA1): c.213-1G> ASNVPathogenicrs80358146GRCh37Chr 17, 41256974: 41256974
1293BRCA1NM_007294.3(BRCA1): c.213-2A> CSNVPathogenicrs397508940GRCh37Chr 17, 41256975: 41256975
1294BRCA1NM_007294.3(BRCA1): c.2142delT (p.Asn714Lysfs)deletionPathogenicrs273898679GRCh37Chr 17, 41245406: 41245406
1295BRCA1NM_007294.3(BRCA1): c.2155A> T (p.Lys719Ter)SNVPathogenicrs80357147GRCh37Chr 17, 41245393: 41245393
1296BRCA1NM_007294.3(BRCA1): c.2155_2168delAAAGAATTTGTCAA (p.Lys719Serfs)deletionPathogenicrs397508941GRCh37Chr 17, 41245380: 41245393
1297BRCA1NM_007294.3(BRCA1): c.2176_2177delCT (p.Leu726Serfs)deletionPathogenicrs397508945GRCh37Chr 17, 41245371: 41245372
1298BRCA1NM_007294.3(BRCA1): c.2176delC (p.Leu726Phefs)deletionPathogenicrs80357668GRCh37Chr 17, 41245372: 41245372
1299BRCA1NM_007294.3(BRCA1): c.2188G> T (p.Glu730Ter)SNVPathogenicrs80357058GRCh37Chr 17, 41245360: 41245360
1300BRCA1NM_007294.3(BRCA1): c.2188_2201delGAAAAAGAAGAGAA (p.Glu730Thrfs)deletionPathogenicrs273898681GRCh37Chr 17, 41245347: 41245360
1301BRCA1NM_007294.3(BRCA1): c.2192_2196delAAGAA (p.Lys731Argfs)deletionPathogenicrs397508946GRCh37Chr 17, 41245352: 41245356
1302BRCA1NM_007294.3(BRCA1): c.2194G> T (p.Glu732Ter)SNVPathogenicrs80357426GRCh37Chr 17, 41245354: 41245354
1303BRCA1NM_007294.3(BRCA1): c.2197G> T (p.Glu733Ter)SNVPathogenicrs397508949GRCh37Chr 17, 41245351: 41245351
1304BRCA1NM_007294.3(BRCA1): c.2197_2201delGAGAA (p.Glu733Thrfs)deletionPathogenicrs80357507GRCh37Chr 17, 41245347: 41245351
1305BRCA1NM_007294.3(BRCA1): c.2202delA (p.Lys734Asnfs)deletionPathogenicrs80357982GRCh37Chr 17, 41245346: 41245346
1306BRCA1NM_007294.3(BRCA1): c.2203delC (p.Leu735Terfs)deletionPathogenicrs80357936GRCh37Chr 17, 41245345: 41245345
1307BRCA1NM_007294.3(BRCA1): c.2206delG (p.Glu736Lysfs)deletionPathogenicrs80357860GRCh37Chr 17, 41245342: 41245342
1308BRCA1NM_007294.3(BRCA1): c.220C> T (p.Gln74Ter)SNVPathogenicrs80357234GRCh37Chr 17, 41256966: 41256966
1309BRCA1NM_007294.3(BRCA1): c.2210delC (p.Thr737Lysfs)deletionPathogenicrs80357793GRCh37Chr 17, 41245338: 41245338
1310BRCA1NM_007294.3(BRCA1): c.2212_2215delGTTA (p.Val738Lysfs)deletionPathogenicrs397508951GRCh37Chr 17, 41245333: 41245336
1311BRCA1NM_007294.3(BRCA1): c.2215A> T (p.Lys739Ter)SNVPathogenicrs56329598GRCh37Chr 17, 41245333: 41245333
1312BRCA1NM_007294.3(BRCA1): c.2216_2217delAA (p.Lys739Serfs)deletionPathogenicrs397508952GRCh37Chr 17, 41245331: 41245332
1313BRCA1NM_007294.3(BRCA1): c.2236dupG (p.Asp746Glyfs)duplicationPathogenicrs80357909GRCh37Chr 17, 41245312: 41245312
1314BRCA1NM_007294.3(BRCA1): c.2241delC (p.Asp749Ilefs)deletionPathogenicrs80357650GRCh37Chr 17, 41245307: 41245307
1315BRCA1NM_007294.3(BRCA1): c.2241dupC (p.Lys748Glnfs)duplicationPathogenicrs397508953GRCh37Chr 17, 41245307: 41245307
1316BRCA1NM_007294.3(BRCA1): c.2248_2252delCTCAT (p.Leu750Valfs)deletionPathogenicrs397508954GRCh37Chr 17, 41245296: 41245300
1317BRCA1NM_007294.3(BRCA1): c.224_227delAAAG (p.Glu75Valfs)deletionPathogenicrs80357697GRCh37Chr 17, 41256959: 41256962
1318BRCA1NM_007294.3(BRCA1): c.2253_2254delGT (p.Met751Ilefs)deletionPathogenicrs80357602GRCh37Chr 17, 41245294: 41245295
1319BRCA1NM_007294.3(BRCA1): c.2263G> T (p.Glu755Ter)SNVPathogenicrs41286296GRCh37Chr 17, 41245285: 41245285
1320BRCA1NM_007294.3(BRCA1): c.2263delG (p.Glu755Lysfs)deletionPathogenicrs80357960GRCh37Chr 17, 41245285: 41245285
1321BRCA1NM_007294.3(BRCA1): c.2275C> T (p.Gln759Ter)SNVPathogenicrs80356999GRCh37Chr 17, 41245273: 41245273
1322BRCA1NM_007294.3(BRCA1): c.2283_2284delAA (p.Arg762Ilefs)deletionPathogenicrs80357657GRCh37Chr 17, 41245264: 41245265
1323BRCA1NM_007294.3(BRCA1): c.2292_2310dup19 (p.Leu771Argfs)duplicationPathogenicrs397508955GRCh37Chr 17, 41245238: 41245256
1324BRCA1NM_007294.3(BRCA1): c.2293G> T (p.Glu765Ter)SNVPathogenicrs80357449GRCh37Chr 17, 41245255: 41245255
1325BRCA1NM_007294.3(BRCA1): c.2314delG (p.Val772Tyrfs)deletionPathogenicrs80357957GRCh37Chr 17, 41245234: 41245234
1326BRCA1NM_007294.3(BRCA1): c.2329delT (p.Tyr777Metfs)deletionPathogenicrs80357725GRCh37Chr 17, 41245219: 41245219
1327BRCA1NM_007294.3(BRCA1): c.232delA (p.Arg78Aspfs)deletionPathogenicrs80357884GRCh37Chr 17, 41256954: 41256954
1328BRCA1NM_007294.3(BRCA1): c.2331T> A (p.Tyr777Ter)SNVPathogenicrs80357444GRCh37Chr 17, 41245217: 41245217
1329BRCA1NM_007294.3(BRCA1): c.2350_2351delTC (p.Ser784Valfs)deletionPathogenicrs397508960GRCh37Chr 17, 41245197: 41245198
1330BRCA1NM_007294.3(BRCA1): c.2351_2357delCGTTACT (p.Ser784Trpfs)deletionPathogenicrs80357820GRCh37Chr 17, 41245191: 41245197
1331BRCA1NM_007294.3(BRCA1): c.2354T> A (p.Leu785Ter)SNVPathogenicrs397508961GRCh37Chr 17, 41245194: 41245194
1332BRCA1NM_007294.3(BRCA1): c.2357delT (p.Leu786Argfs)deletionPathogenicrs397508963GRCh37Chr 17, 41245191: 41245191
1333BRCA1NM_007294.3(BRCA1): c.2359delG (p.Glu787Lysfs)deletionPathogenicrs397508964GRCh37Chr 17, 41245189: 41245189
1334BRCA1NM_007294.3(BRCA1): c.2359dupG (p.Glu787Glyfs)duplicationPathogenicrs80357739GRCh37Chr 17, 41245189: 41245189
1335BRCA1NM_007294.3(BRCA1): c.2389_2390delGA (p.Glu797Thrfs)deletionPathogenicrs80357695GRCh37Chr 17, 41245158: 41245159
1336BRCA1NM_007294.3(BRCA1): c.2390_2391delAA (p.Glu797Alafs)deletionPathogenicrs80357546GRCh37Chr 17, 41245157: 41245158
1337BRCA1NM_007294.3(BRCA1): c.2393delC (p.Pro798Glnfs)deletionPathogenicrs80357850GRCh37Chr 17, 41245155: 41245155
1338BRCA1NM_007294.3(BRCA1): c.2403T> A (p.Cys801Ter)SNVPathogenicrs80357381GRCh37Chr 17, 41245145: 41245145
1339BRCA1NM_007294.3(BRCA1): c.2405_2406delTG (p.Val802Glufs)deletionPathogenicrs80357706GRCh37Chr 17, 41245142: 41245143
1340BRCA1NM_007294.3(BRCA1): c.2406_2409delGAGT (p.Gln804Valfs)deletionPathogenicrs80357674GRCh37Chr 17, 41245139: 41245142
1341BRCA1NM_007294.3(BRCA1): c.2410C> T (p.Gln804Ter)SNVPathogenicrs80356982GRCh37Chr 17, 41245138: 41245138
1342BRCA1NM_007294.3(BRCA1): c.241C> T (p.Gln81Ter)SNVPathogenicrs80357350GRCh37Chr 17, 41256945: 41256945
1343BRCA1NM_007294.3(BRCA1): c.2429delA (p.Asn810Thrfs)deletionPathogenicrs397508967GRCh37Chr 17, 41245119: 41245119
1344BRCA1NM_007294.3(BRCA1): c.2434A> T (p.Lys812Ter)SNVPathogenicrs397508968GRCh37Chr 17, 41245114: 41245114
1345BRCA1NM_007294.3(BRCA1): c.2437G> T (p.Gly813Ter)SNVPathogenicrs80357186GRCh37Chr 17, 41245111: 41245111
1346BRCA1NM_007294.3(BRCA1): c.2450delG (p.Gly817Valfs)deletionPathogenicrs80357679GRCh37Chr 17, 41245098: 41245098
1347BRCA1NM_007294.3(BRCA1): c.2468delG (p.Arg823Lysfs)deletionPathogenicrs80357799GRCh37Chr 17, 41245080: 41245080
1348BRCA1NM_007294.3(BRCA1): c.2476delA (p.Thr826Glnfs)deletionPathogenicrs80357631GRCh37Chr 17, 41245072: 41245072
1349BRCA1NM_007294.3(BRCA1): c.2477_2478delCA (p.Thr826Argfs)deletionPathogenicrs80357800GRCh37Chr 17, 41245070: 41245071
1350BRCA1NM_007294.3(BRCA1): c.2477delC (p.Thr826Lysfs)deletionPathogenicrs80357740GRCh37Chr 17, 41245071: 41245071
1351BRCA1NM_007294.3(BRCA1): c.2487delT (p.Phe829Leufs)deletionPathogenicrs80357658GRCh37Chr 17, 41245061: 41245061
1352BRCA1NM_007294.3(BRCA1): c.2487dupT (p.Lys830Terfs)duplicationPathogenicrs397508972GRCh37Chr 17, 41245061: 41245061
1353BRCA1NM_007294.3(BRCA1): c.2488_2497dupAAGTATCCAT (p.Leu833Terfs)duplicationPathogenicrs397508973GRCh37Chr 17, 41245051: 41245060
1354BRCA1NM_007294.3(BRCA1): c.2507_2508delAA (p.Glu836Glyfs)deletionPathogenicrs273899686GRCh37Chr 17, 41245040: 41245041
1355BRCA1NM_007294.3(BRCA1): c.2513delA (p.Asn838Thrfs)deletionPathogenicrs80357863GRCh37Chr 17, 41245035: 41245035
1356BRCA1NM_007294.3(BRCA1): c.2517_2518delCA (p.His839Glnfs)deletionPathogenicrs397508974GRCh37Chr 17, 41245030: 41245031
1357BRCA1NM_007294.3(BRCA1): c.2518delA (p.Ser840Valfs)deletionPathogenicrs397508975GRCh37Chr 17, 41245030: 41245030
1358BRCA1NM_007294.3(BRCA1): c.2545G> T (p.Glu849Ter)SNVPathogenicrs80356951GRCh37Chr 17, 41245003: 41245003
1359BRCA1NM_007294.3(BRCA1): c.2558dupA (p.Asp853Glufs)duplicationPathogenicrs80357835GRCh37Chr 17, 41244990: 41244990
1360BRCA1NM_007294.3(BRCA1): c.2560_2561dupGC (p.Gln855Leufs)duplicationPathogenicrs80357968GRCh37Chr 17, 41244987: 41244988
1361BRCA1NM_007294.3(BRCA1): c.2561_2565delCTCAG (p.Ala854Valfs)deletionPathogenicrs397508981GRCh37Chr 17, 41244983: 41244987
1362BRCA1