MCID: FML118
MIFTS: 22

Familial Creutzfeldt-Jakob Disease malady

Genetic diseases category

Summaries for Familial Creutzfeldt-Jakob Disease

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32MalaCards
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MalaCards: Familial Creutzfeldt-Jakob Disease, also known as creutzfeldt-jakob disease, familial, is related to prion disease and fatal familial insomnia. An important gene associated with Familial Creutzfeldt-Jakob Disease is PRNP (prion protein). The compounds formate and guanidine have been mentioned in the context of this disorder. Related mouse phenotype reproductive system.

Aliases & Classifications for Familial Creutzfeldt-Jakob Disease

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20GeneTests, 44Novoseek, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases


Aliases & Descriptions:

familial creutzfeldt-jakob disease 20 44
creutzfeldt-jakob disease, familial 60


Related Diseases for Familial Creutzfeldt-Jakob Disease

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Familial Creutzfeldt-Jakob Disease:



Diseases related to familial creutzfeldt-jakob disease

Clinical Features for Familial Creutzfeldt-Jakob Disease

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Drugs & Therapeutics for Familial Creutzfeldt-Jakob Disease

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Familial Creutzfeldt-Jakob Disease

Drug clinical trials:

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Search NIH Clinical Center for Familial Creutzfeldt-Jakob Disease

Search CenterWatch for Familial Creutzfeldt-Jakob Disease

Genetic Tests for Familial Creutzfeldt-Jakob Disease

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20GeneTests
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Genetic tests related to Familial Creutzfeldt-Jakob Disease:

id Genetic test Affiliating Genes
1 Familial Creutzfeldt-Jakob Disease20 PRNP

Anatomical Context for Familial Creutzfeldt-Jakob Disease

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Animal Models for Familial Creutzfeldt-Jakob Disease or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Familial Creutzfeldt-Jakob Disease:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.1MSMB, PRNP, PRND, APOE

Publications for Familial Creutzfeldt-Jakob Disease

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Genetic Variations for Familial Creutzfeldt-Jakob Disease

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Expression for genes affiliated with Familial Creutzfeldt-Jakob Disease

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Familial Creutzfeldt-Jakob Disease

Search GEO for disease gene expression data for Familial Creutzfeldt-Jakob Disease.

Pathways for genes affiliated with Familial Creutzfeldt-Jakob Disease

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Compounds for genes affiliated with Familial Creutzfeldt-Jakob Disease

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44Novoseek, 11DrugBank, 24HMDB
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Compounds related to Familial Creutzfeldt-Jakob Disease according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1formate449.3PRNP, APOE
2guanidine44 11 2411.2APOE, PRNP
3sodium dodecylsulfate449.1PRNP, APOE
4biotin44 11 2410.8GSS, APOE
5valine448.8PRNP, PRND, APOE
6guanidine hydrochloride448.7MSMB, PRNP, APOE
7glutamate448.7GSS, PRNP, APOE

GO Terms for genes affiliated with Familial Creutzfeldt-Jakob Disease

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Sources:
16Gene Ontology
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Cellular components related to Familial Creutzfeldt-Jakob Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1anchored to membraneGO:0312259.5PRNP, PRND

Biological processes related to Familial Creutzfeldt-Jakob Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cellular copper ion homeostasisGO:0068789.5PRNP, PRND
2response to cadmium ionGO:0466869.4GSS, PRNP
3response to oxidative stressGO:0069799.2GSS, PRNP
4agingGO:0075689.1GSS, APOE

Molecular functions related to Familial Creutzfeldt-Jakob Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1copper ion bindingGO:0055079.5PRNP, PRND

Products for genes affiliated with Familial Creutzfeldt-Jakob Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Familial Creutzfeldt-Jakob Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet