MCID: FML118
MIFTS: 24

Familial Creutzfeldt-Jakob Disease malady

Categories: Genetic diseases, Rare diseases, Infectious diseases, Neuronal diseases, Mental diseases

Aliases & Classifications for Familial Creutzfeldt-Jakob Disease

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Sources:
22GeneTests, 47Novoseek, 65UMLS
See all MalaCards sources

Aliases & Descriptions for Familial Creutzfeldt-Jakob Disease:

Name: Familial Creutzfeldt-Jakob Disease 22 47
Creutzfeldt-Jakob Disease, Familial 65
 
Fcjd 22

Classifications:



External Ids:

UMLS65 C0751254

Summaries for Familial Creutzfeldt-Jakob Disease

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MalaCards based summary: Familial Creutzfeldt-Jakob Disease, also known as creutzfeldt-jakob disease, familial, is related to hemolytic-uremic syndrome and endotheliitis. An important gene associated with Familial Creutzfeldt-Jakob Disease is PRNP (Prion Protein). Affiliated tissues include t cells, liver and breast, and related mouse phenotype reproductive system.

Related Diseases for Familial Creutzfeldt-Jakob Disease

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Graphical network of the top 20 diseases related to Familial Creutzfeldt-Jakob Disease:



Diseases related to familial creutzfeldt-jakob disease

Symptoms for Familial Creutzfeldt-Jakob Disease

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Drugs & Therapeutics for Familial Creutzfeldt-Jakob Disease

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Enhanced CJD Surveillance in the Older PopulationRecruitingNCT02629640

Search NIH Clinical Center for Familial Creutzfeldt-Jakob Disease

Genetic Tests for Familial Creutzfeldt-Jakob Disease

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Genetic tests related to Familial Creutzfeldt-Jakob Disease:

id Genetic test Affiliating Genes
1 Familial Creutzfeldt-Jakob Disease22 PRNP

Anatomical Context for Familial Creutzfeldt-Jakob Disease

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MalaCards organs/tissues related to Familial Creutzfeldt-Jakob Disease:

33
T cells, Liver, Breast, Prostate, Skin, Colon, B cells

Animal Models for Familial Creutzfeldt-Jakob Disease or affiliated genes

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MGI Mouse Phenotypes related to Familial Creutzfeldt-Jakob Disease:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.4APOE, MSMB, PRND, PRNP

Publications for Familial Creutzfeldt-Jakob Disease

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Articles related to Familial Creutzfeldt-Jakob Disease:

(show top 50)    (show all 77)
idTitleAuthorsYear
1
Substernal goiter: Experience with 50A cases. (26520480)
2015
2
Glomerular filtration rates in healthy Asians without kidney disease. (24279633)
2014
3
Should the presence of an antiphospholipid antibody affect the duration of anticoagulant treatment in patients with venous thromboembolism? (24319252)
2013
4
Alterations in the peripheral blood B cell subpopulations of multidrug-resistant tuberculosis patients. (24068613)
2013
5
Immunohistochemical analysis of prognostic protein markers for primary localized clear cell renal cell carcinoma. (23327192)
2013
6
The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients. (24355598)
2013
7
Regulation of NOX-1 expression in beta cells: a positive feedback loop involving the Src-kinase signaling pathway. (23410839)
2013
8
Sal-like 4 (SALL4) suppresses CDH1 expression and maintains cell dispersion in basal-like breast cancer. (23954296)
2013
9
Improvement in chronic pelvic pain after gonadotropin releasing hormone analogue (GnRH-a) administration in premenopausal women suffering from adenomyosis or endometriosis: a retrospective study. (23323768)
2013
10
Long-standing invasive squamous cell carcinoma in a 55-year-old man. (24270032)
2013
11
IFNI^/TNFI+ specific-cells and effector memory phenotype associate with active tuberculosis. (23462597)
2013
12
Adrenal function in cats with hyperthyroidism. (22373912)
2012
13
Diagnostic accuracy of indirect immunofluorescence assay for intestinal invasive amebiasis and impact of HIV infection in a non-endemic country. (23017259)
2012
14
A preliminary study on the regulation mechanism of p38MAPK on MUC5AC in allergic rhinitis]. (22239058)
2011
15
Pridopidine in treatment of Huntington's disease: beyond chorea? (22071278)
2011
16
Interaction of immunological genes on chromosome 2q33 and IFNG in susceptibility to cervical cancer. (19959217)
2010
17
Chemical colitis due to glutaraldehyde: case series and review of the literature. (19104938)
2009
18
Argon laser iridotomy-induced bullous keratopathy. (19471010)
2009
19
Remarks on the acute intermittent porphyria. (19564164)
2009
20
Detecting pathway-based gene-gene and gene-environment interactions in pancreatic cancer. (18559563)
2008
21
Dynamics of bidirectional transport of Arc mRNA in neuronal dendrites. (17120280)
2007
22
The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. (17668068)
2007
23
A novel factor XI gene mutation associated with mild factor XI deficiency in a symptomatic patient. (16905957)
2006
24
Reduced serum levels of brain-derived neurotrophic factor in adult male patients with autism. (16876305)
2006
25
Validation of basophil histamine release against the autologous serum skin test and outcome of serum-induced basophil histamine release studies in a large population of chronic urticaria patients. (16076300)
2005
26
Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis. (15994948)
2005
27
Alpha B-crystallin, a new independent marker for poor prognosis in head and neck cancer. (15995513)
2005
28
Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism. (12902032)
2003
29
Three-day intravenous triple therapy is not effective for the eradication of Helicobacter pylori infection in patients with bleeding gastro-duodenal ulcer. (14616169)
2003
30
Simultaneous detection of colonic epithelial cells in portal venous and peripheral blood during colorectal cancer surgery. (11786759)
2002
31
Characterization of the gene encoding mouse retinoblastoma binding protein-7, a component of chromatin-remodeling complexes. (12376095)
2002
32
Differential regulation of heterodimerization by 1alpha,25-dihydroxyvitamin D(3) and its 20-epi analog. (11179727)
2001
33
Matrix gla protein is regulated by a mechanism functionally related to the calcium-sensing receptor. (11062022)
2000
34
The C-class chemokine, lymphotactin, impairs the induction of Th1-type lymphokines in human CD4(+) T cells. (10887101)
2000
35
Differential expression of metallothioneins in human prion diseases. (10940676)
2000
36
Defining folding and unfolding reactions of apocytochrome b5 using equilibrium and kinetic fluorescence measurements. (10413531)
1999
37
p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons. (10523304)
1999
38
Protein kinase C-zeta activity but not level is decreased in Alzheimer's disease microvessels. (9780084)
1998
39
Viral meningitis. (20401230)
1998
40
Domain structure and intramolecular regulation of dynamin GTPase. (9362482)
1997
41
The nuclear deltaB isoform of Ca2+/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes. (9388275)
1997
42
Adrenarche is associated with decreased 3 beta-hydroxysteroid dehydrogenase expression in the adrenal reticularis. (8969933)
1996
43
Identification of a homozygous one-basepair deletion in exon 14 of the LAMB3 gene in a patient with Herlitz junctional epidermolysis bullosa and prenatal diagnosis in a family at risk for recurrence. (7706759)
1995
44
Steroid hormone receptor content and lymph node status in endometrial cancer. (7705676)
1995
45
Giant axonal neuropathy with predominant central nervous system manifestations. (1310292)
1992
46
Coronary ostial endarterectomy in Takayasu's aortitis--confirmation of patency nine years postsurgically. (1352558)
1992
47
Cytokine induction in HTLV-I associated myelopathy and adult T-cell leukemia: alternate molecular mechanisms underlying retroviral pathogenesis. (1757474)
1991
48
Response of malignant glioma cell lines to epidermal growth factor and platelet-derived growth factor in a serum-free medium. (2352010)
1990
49
Natal teeth, patent ductus arteriosus and intestinal pseudo-obstruction: a lethal syndrome in the newborn. (1269170)
1976
50
Alpha-chain disease and its association with intestinal lymphoma. (826361)
1976

Variations for Familial Creutzfeldt-Jakob Disease

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Expression for genes affiliated with Familial Creutzfeldt-Jakob Disease

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Search GEO for disease gene expression data for Familial Creutzfeldt-Jakob Disease.

Pathways for genes affiliated with Familial Creutzfeldt-Jakob Disease

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GO Terms for genes affiliated with Familial Creutzfeldt-Jakob Disease

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Biological processes related to Familial Creutzfeldt-Jakob Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to oxidative stressGO:00069799.5APOE, PRNP

Sources for Familial Creutzfeldt-Jakob Disease

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet