MCID: FML016
MIFTS: 52

Familial Hypertriglyceridemia malady

Genetic diseases, Endocrine diseases, Rare diseases categories
Download this MalaCard

Summaries for Familial Hypertriglyceridemia

About this section
Sources:
8Disease Ontology, 65Wikipedia, 47OMIM, 33MalaCards
See all sources

Fully expand this MalaCard
Disease Ontology:8 A lipid metabolism disorder characterized by elevated triglyceride levels as a result of excess hepatic production of vldl or heterozygous lpl deficiency.

MalaCards: Familial Hypertriglyceridemia, also known as hypertriglyceridemias familial, is related to hypertriglyceridemia and familial combined hyperlipidemia. An important gene associated with Familial Hypertriglyceridemia is SLC10A2 (solute carrier family 10 (sodium/bile acid cotransporter), member 2), and among its related pathways are Cholesterol and Sphingolipids transport Recycling to plasma membrane in lung normal and CF and Vitamin digestion and absorption. The compounds polyethylene glycol 6000 and maxepa have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and lung, and related mouse phenotypes are liver/biliary system and cardiovascular system.

Wikipedia:65 Familial hypertriglyceridemia is an autosomal dominant condition occurring in approximately 1% of the... more...

Description from OMIM:47 145750

Aliases & Classifications for Familial Hypertriglyceridemia

About this section
Sources:
62UMLS, 8Disease Ontology, 22GTR, 10DISEASES, 45Novoseek, 47OMIM
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Endocrine diseases


Aliases & Descriptions:

familial hypertriglyceridemia 8 22 10
hypertriglyceridemias familial 45
hyperlipoproteinemia type iv 62
pure hyperglyceridemia 8


External Ids:

Disease Ontology8 DOID:0050527
OMIM47 145750

Related Diseases for Familial Hypertriglyceridemia

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Hypertriglyceridemia family:

familial hypertriglyceridemia

Diseases related to Familial Hypertriglyceridemia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1hypertriglyceridemia31.0LPL, APOA2, APOC3, APOA1, APOE, APOB
2familial combined hyperlipidemia30.7APOA1, APOB, APOE
3coronary artery disease29.9APOA1, APOB, LPL
4obesity29.9APOC3, APOA2, LPL, APOB, APOE, USF1
5familial hypercholesterolemia29.9APOE, APOA1, APOB, LPL
6hypercholesterolemia29.7SLC10A2, LPL, APOB, APOA2, APOC3, APOE
7pancreatitis10.3
8steatorrhea10.1SLC10A2
9chylomicron retention disease10.1APOB
10lipoprotein glomerulopathy10.1APOE
11cerebral atherosclerosis10.1APOA1
12fish-eye disease10.0APOA1, APOA2
13complete lcat deficiency10.0APOA1, APOA2
14amyloidosis, renal10.0APOA2, APOA1
15age related macular degeneration10.0APOE, APOB
16arcus senilis10.0APOB, APOA1
17amyloid tumor10.0APOE, APOA2
18peripheral vascular disease10.0APOA1, APOB
19acute pancreatitis10.0
20familial lipoprotein lipase deficiency10.0
21artery disease10.0
22coronary stenosis10.0APOB, APOA1
23hyperlipoproteinemia type v10.0APOE, LPL
24hepatoblastoma10.0APOA2, APOB, APOA1
25hypobetalipoproteinemia10.0APOB, APOA1, APOE
26stroke, ischemic10.0APOA1, APOB, APOE
27hyperinsulinism10.0LPL, APOB
28pancreatitis, chronic10.0APOB, LPL
29lipodystrophy10.0APOB, LPL, APOC3
30diabetic nephropathy10.0APOB, APOE, APOA1
31glucose intolerance10.0LPL, APOB
32xanthomatosis10.0APOE, LPL, APOB
33hyperalphalipoproteinemia10.0APOA2, APOA1, APOB, APOC3
34galactosemia9.9APOA1, APOC3, SLC10A2, APOB
35proteinuria9.9APOA1, APOA2, APOC3, APOB
36arteriosclerosis9.9APOA1, APOB, LPL
37uremia9.9LPL, APOC3
38essential hypertension9.9LPL, APOB, APOA1
39cerebrovascular disease9.9LPL, APOE, APOB
40primary hyperoxaluria9.9APOB, APOC3, APOE, APOA1
41chronic kidney failure9.9APOB, LPL, APOA1
42amyloidosis9.9APOE, APOA1, APOA2, LPL
43metabolic syndrome x9.9LPL, APOB, APOA1, USF1
44fatty liver disease9.9APOB, APOA1, LPL, APOC3
45hyperlipidemia type 39.9APOE, APOA1, APOB, LPL
46abetalipoproteinemia9.9APOB, APOE, APOA1, LPL
47nephrotic syndrome9.9APOA1, APOE, LPL, APOB
48myocardial infarction9.9APOE, APOA1, APOC3, APOB, APOA2
49hypertension9.9LPL, APOE, APOB, APOA1
50vascular disease9.9APOB, LPL, APOE, APOA1

Graphical network of the top 20 diseases related to Familial Hypertriglyceridemia:



Diseases related to familial hypertriglyceridemia

Symptoms for Familial Hypertriglyceridemia

About this section
Sources:
47OMIM
See all sources


Clinical features from OMIM:

145750

Drugs & Therapeutics for Familial Hypertriglyceridemia

About this section
Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
See all sources

Drug clinical trials:

Search ClinicalTrials for Familial Hypertriglyceridemia

Search NIH Clinical Center for Familial Hypertriglyceridemia

Genetic Tests for Familial Hypertriglyceridemia

About this section
Sources:
22GTR
See all sources

Genetic tests related to Familial Hypertriglyceridemia:

id Genetic test Affiliating Genes
1 Familial Hypertriglyceridemia22

Anatomical Context for Familial Hypertriglyceridemia

About this section
Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Familial Hypertriglyceridemia:

33
Heart, Liver, Lung

Animal Models for Familial Hypertriglyceridemia or affiliated genes

About this section
Sources:
37MGI
See all sources

MGI Mouse Phenotypes related to Familial Hypertriglyceridemia:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053707.5APOE, APOA1, APOB, LPL, SLC10A2
2MP:00053857.5LPL, APOB, APOC3, APOA1, APOE
3MP:00053787.1APOE, APOC3, APOA2, APOB, LPL, SLC10A2
4MP:00053766.8SLC10A2, LPL, APOB, APOA2, APOC3, APOA1

Publications for Familial Hypertriglyceridemia

About this section
Sources:
52PubMed
See all sources

Articles related to Familial Hypertriglyceridemia:

(show all 42)
idTitleAuthorsYear
1
Management of Familial Hypertriglyceridemia-Induced Pancreatitis During Pregnancy With Therapeutic Plasma Exchange: A Case Report and Review of Literature. (22926234)
2012
2
Serum ferritin is a major determinant of lipid phenotype in familial combined hyperlipidemia and familial hypertriglyceridemia. (19913843)
2010
3
Iron deposits and dietary patterns in familial combined hyperlipidemia and familial hypertriglyceridemia. (20645139)
2010
4
Management of familial hypertriglyceridemia during pregnancy with plasma exchange. (19160449)
2009
5
Linkage analysis of a family with familial hypertriglyceridemia]. (19806567)
2009
6
Familial hypertriglyceridemia. (19057857)
2008
7
Apolipoprotein B is associated with metabolic syndrome in Chinese families with familial combined hyperlipidemia, familial hypertriglyceridemia and familial hypercholesterolemia. (16828905)
2007
8
Genome-wide scan for quantitative trait loci influencing LDL size and plasma triglyceride in familial hypertriglyceridemia. (12923221)
2003
9
Coronary artery disease risk in familial combined hyperlipidemia and familial hypertriglyceridemia: a case-control comparison from the National Heart, Lung, and Blood Institute Family Heart Study. (12847072)
2003
10
An observational study of severe hypertriglyceridemia, hypertriglyceridemic acute pancreatitis, and failure of triglyceride-lowering therapy when estrogens are given to women with and without familial hypertriglyceridemia. (12763274)
2003
11
Analysis of the ileal bile acid transporter gene, SLC10A2, in subjects with familial hypertriglyceridemia. (11742882)
2001
12
Lipoprotein(a) as a risk factor for maternal cardiovascular disease mortality in kindreds with familial combined hyperlipidemia or familial hypertriglyceridemia. (11595020)
2001
13
Platelet function in patients with familial hypertriglyceridemia: evidence that platelet reactivity is modulated by apolipoprotein E content of very-low-density lipoprotein particles. (10910008)
2000
14
Postprandial hemorrheology and apolipoprotein B metabolism in patients with familial hypertriglyceridemia. (9361689)
1997
15
Effects of n-3 fatty acids and fenofibrate on lipid and hemorrheological parameters in familial dysbetalipoproteinemia and familial hypertriglyceridemia. (8843189)
1996
16
In vitro lipolysis of human VLDL: effect of different VLDL compositions in normolipidemia, familial combined hyperlipidemia and familial hypertriglyceridemia. (8678926)
1996
17
Treatment of severe familial hypertriglyceridemia during pregnancy with very-low-fat diet and n-3 fatty acids. (8798226)
1996
18
Primary chylomicronemia in patients with severe familial hypertriglyceridemia responds to long-term treatment with (n-3) fatty acids. (7782902)
1995
19
Abnormal bile acid absorption in familial hypertriglyceridemia. (7706952)
1995
20
No evidence for linkage between familial hypertriglyceridemia and apolipoprotein B, apolipoprotein C-III or lipoprotein lipase genes. (8076943)
1994
21
Does familial hypertriglyceridemia predispose to NIDDM? (8299439)
1993
22
Treatment of primary chylomicronemia due to familial hypertriglyceridemia by omega-3 fatty acids. (1406295)
1992
23
Effect of dietary treatment on the lipid, lipoprotein and fatty acid compositions in type IV familial hypertriglyceridemia. (1776822)
1991
24
HDL metabolism in HDL deficiency associated with familial hypertriglyceridemia: effect of treatment with gemfibrozil. (1907081)
1991
25
Familial hypertriglyceridemia aggravated by diabetes and drugs. (3331728)
1987
26
Bile acid metabolism in hereditary forms of hypertriglyceridemia: evidence for an increased synthesis rate in monogenic familial hypertriglyceridemia. (3474660)
1987
27
DNA polymorphisms of apolipoprotein A-I/C-III and insulin genes in familial hypertriglyceridemia and coronary heart disease. (3115275)
1987
28
Plasma lipoproteins, apolipoproteins, and triglyceride metabolism in familial hypertriglyceridemia. (3729796)
1986
29
Apolipoprotein AI and AII metabolism in patients with primary high-density lipoprotein deficiency associated with familial hypertriglyceridemia. (3927110)
1985
30
Apolipoprotein B-48 and B-100 very low density lipoproteins. Comparison in dysbetalipoproteinemia (type III) and familial hypertriglyceridemia (type IV). (3977778)
1985
31
The response of plasma triglyceride, cholesterol, and lipoprotein lipase to treatment in non-insulin-dependent diabetic subjects without familial hypertriglyceridemia. (6354782)
1983
32
Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia. (6403642)
1983
33
Prevalence of familial hypertriglyceridemia: the Princeton School District Family Study. (7111228)
1982
34
Integrated regulation of very low density lipoprotein triglyceride and apolipoprotein-B kinetics in man: normolipemic subjects, familial hypertriglyceridemia and familial combined hyperlipidemia. (7266376)
1981
35
Pancreatitis, familial hypertriglyceridemia, and pregnancy. (7355961)
1980
36
Interactions of obesity and glucose-stimulated insulin secretion in familial hypertriglyceridemia. (658614)
1978
37
Familial hypertriglyceridemia in children: dietary management. (904981)
1977
38
Insulin, obesity, and triglyceride interrelationships in sixteen children with familial hypertriglyceridemia. (318742)
1977
39
Plasma triglyceride and insulin levels in familial hypertriglyceridemia. (889202)
1977
40
Juvenile familial hypertriglyceridemia and growth retardation. Clinical and biochemical observations in three siblings. (192555)
1977
41
Serum lipids in alcoholic patients with and without cirrhosis of the liver, with particular reference to endogenous familial hypertriglyceridemia. (184708)
1976
42
Familial hypertriglyceridemia: studies in 130 children and 45 siblings of 36 index cases. (4784529)
1973

Variations for Familial Hypertriglyceridemia

About this section

Expression for genes affiliated with Familial Hypertriglyceridemia

About this section
Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Familial Hypertriglyceridemia

Search GEO for disease gene expression data for Familial Hypertriglyceridemia.

Pathways for genes affiliated with Familial Hypertriglyceridemia

About this section
Sources:
50PathCards, 60Thomson Reuters, 30KEGG, 55Reactome, 38NCBI BioSystems Database, 12EMD Millipore, 51PharmGKB
See all sources

Pathways related to Familial Hypertriglyceridemia according to GeneCards/GeneDecks:

(show all 15)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5APOA1, APOA2
29.3APOB, APOA1
3
Show member pathways
9.3APOB, APOA1
4
Show member pathways
thioredoxin pathway38
9.3APOB, APOA1
5
Show member pathways
Vitamin B12 Metabolism38
9.3APOA1, APOE
69.0APOB, APOA2, APOA1
7
Show member pathways
8.8APOA1, APOE, APOB
8
Show member pathways
8.7LPL, APOA2, APOA1
9
Show member pathways
fatty acid beta-oxidation VI (peroxisome)38
8.2APOA1, APOC3, LPL, APOA2
10
Show member pathways
7.2APOE, APOA1, APOA2, APOB, APOC3, LPL
11
Show member pathways
7.2LPL, APOE, APOB, APOA2, APOC3, APOA1
12
Show member pathways
7.2APOE, APOA1, LPL, APOB, APOA2, APOC3
137.2LPL, APOE, APOA2, APOC3, APOA1, APOB
14
Show member pathways
7.2APOA1, APOE, LPL, APOC3, APOA2, APOB
15
Show member pathways
6.8APOA1, SLC10A2, APOB, APOE, APOC3, APOA2

Compounds for genes affiliated with Familial Hypertriglyceridemia

About this section
Sources:
45Novoseek, 24HMDB, 29IUPHAR, 51PharmGKB, 11DrugBank, 3BitterDB, 61Tocris Bioscience
See all sources

Compounds related to Familial Hypertriglyceridemia according to GeneCards/GeneDecks:

(show top 50)    (show all 111)
idCompoundScoreTop Affiliating Genes
1polyethylene glycol 6000459.4APOB, APOA1
2maxepa459.4APOA1, APOB
3cholestyramine459.3APOB, APOC3, APOE
4lynestrenol459.3APOB, APOA1
5dimyristoylphosphatidylcholine459.3APOE, APOA1, APOA2
6campesterol45 2410.2APOE, APOA1, APOB
77-ketocholesterol45 2410.1APOA1, APOB, APOE
8sele459.0APOE, LPL, APOC3
9mspi458.9APOA1, APOB, APOA2, APOC3
10ciprofibrate45 299.9LPL, APOA1, APOB
11rosuvastatin45 51 29 1111.8APOB, APOC3, APOA1, APOE
12tocopherol458.8APOA1, APOB, LPL
13homocysteine45 249.7APOE, APOA1, APOC3, APOB
14niacin45 119.7APOA1, LPL, APOB
15ritonavir45 51 1110.6LPL, APOC3, APOE
16xbai458.6APOB, APOE, APOC3, LPL
17fenofibric acid45 299.5APOA1, APOC3, APOB, LPL
18rosiglitazone29 45 51 24 1112.5APOE, LPL, APOB, APOC3
19sterol458.5APOE, APOA1, APOB, USF1, SLC10A2
20chloramphenicol45 3 51 1111.4USF1, APOB, LPL, APOC3
21retinyl palmitate45 249.4APOB, APOA1, APOE, LPL
22probucol45 119.4APOA1, LPL, APOE, APOB
23fluvastatin45 51 29 1111.4LPL, APOB, APOA1, APOE
24alpha tocopherol458.3APOB, LPL, APOE, APOA1
25palmitate458.3APOE, APOA1, APOB, LPL
26guanine45 24 1110.3LPL, APOA1, APOE, USF1
27simvastatin45 51 61 29 24 1113.3APOA1, APOB, APOE, LPL
28thyroxine45 249.2APOB, LPL, APOA1, APOE
29fatty acid458.2USF1, LPL, APOB, APOA2, APOC3
30taurocholate458.1LPL, APOC3, APOA1, SLC10A2, APOB
31heparin45 29 24 1111.1LPL, APOE, APOA2, APOB, APOC3
32phosphatidylcholine458.0APOA1, APOE, APOA2, APOB, LPL
33lovastatin45 51 61 29 1111.9APOE, LPL, APOA1, APOC3, APOB
34vitamin a45 24 119.9APOB, APOC3, LPL, APOE, APOA1
35testosterone45 61 24 1110.7APOE, LPL, APOB, APOC3, APOA1
36tamoxifen45 51 29 1110.7APOA1, APOE, LPL, APOB
37serine457.6SLC10A2, APOB, APOA2, APOC3, APOA1, APOE
38pravastatin45 51 29 24 1111.6APOC3, APOE, SLC10A2, APOA1, LPL, APOB
39atorvastatin45 51 29 24 1111.6LPL, APOB, APOC3, APOA1, APOE, SLC10A2
40cholesterol ester457.6LPL, APOE, APOA1, APOA2, APOB, APOC3
41bezafibrate45 29 119.6APOA2, LPL, APOB, APOC3, APOA1, APOE
42intralipid457.6LPL, APOB, APOA2, APOC3, APOA1, APOE
43gemfibrozil29 45 119.6APOC3, APOA1, APOA2, APOB, LPL, APOE
44fenofibrate45 51 119.6APOE, APOA1, APOA2, APOB, LPL, APOC3
45glucose457.6APOA2, APOB, LPL, USF1, APOC3, APOA1
46triacylglycerol457.6APOB, APOC3, APOA2, APOA1, LPL, APOE
47phospholipid457.6APOA2, LPL, APOB, APOE, APOA1, APOC3
48estrogen457.2APOC3, APOA2, APOB, APOA1, LPL, USF1
49cholesterol45 29 24 119.8SLC10A2, APOB, APOA2, APOC3, APOE, USF1
50lipid456.8APOC3, APOA1, USF1, SLC10A2, LPL, APOA2

GO Terms for genes affiliated with Familial Hypertriglyceridemia

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Familial Hypertriglyceridemia according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1spherical high-density lipoprotein particleGO:0343669.2APOA2, APOC3, APOA1
2intermediate-density lipoprotein particleGO:0343639.2APOB, APOC3, APOE
3low-density lipoprotein particleGO:0343629.1APOE, APOB
4high-density lipoprotein particleGO:0343649.1APOA2, APOA1, APOE
5endoplasmic reticulum lumenGO:0057889.0APOB, APOA2, APOA1
6endocytic vesicle lumenGO:0716829.0APOE, APOA1, APOB
7blood microparticleGO:0725628.9APOA2, APOA1, APOE
8early endosomeGO:0057698.2APOE, APOA1, APOC3, APOA2, APOB
9chylomicronGO:0426278.0APOE, APOC3, APOA2, APOB, LPL
10extracellular spaceGO:0056157.5APOE, APOA1, APOC3, APOB, LPL
11very-low-density lipoprotein particleGO:0343617.4LPL, APOB, APOA2, APOC3, APOA1, APOE
12extracellular regionGO:0055767.2APOE, APOA1, APOC3, APOA2, APOB, LPL

Biological processes related to Familial Hypertriglyceridemia according to GeneCards/GeneDecks:

(show all 46)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of cholesterol importGO:06062110.0APOA2, APOC3
2negative regulation of lipid catabolic processGO:0509959.9APOC3, APOA2
3negative regulation of lipase activityGO:0601929.8APOA2, APOA1
4regulation of intestinal cholesterol absorptionGO:0303009.8APOA1, APOA2
5triglyceride mobilizationGO:0066429.8APOC3, APOB
6protein oxidationGO:0181589.8APOA1, APOA2
7chylomicron remnant clearanceGO:0343829.8APOE, APOC3
8negative regulation of cytokine secretion involved in immune responseGO:0027409.8APOA1, APOA2
9lipoprotein catabolic processGO:0421599.8APOE, APOB
10peptidyl-methionine modificationGO:0182069.8APOA1, APOA2
11very-low-density lipoprotein particle assemblyGO:0343799.8APOB, APOC3
12lipoprotein transportGO:0429539.7APOC3, APOB
13peripheral nervous system axon regenerationGO:0140129.7APOE, APOA1
14phosphatidylcholine biosynthetic processGO:0066569.6APOA2, APOA1
15artery morphogenesisGO:0488449.6APOE, APOB
16cholesterol transportGO:0303019.6APOA1, APOB
17organ regenerationGO:0311009.5APOA2, APOA1
18response to estrogenGO:0436279.5APOA1, APOA2
19low-density lipoprotein particle remodelingGO:0343749.4APOE, APOA2, APOB
20negative regulation of very-low-density lipoprotein particle remodelingGO:0109039.4APOA2, APOC3, APOA1
21very-low-density lipoprotein particle remodelingGO:0343729.4APOE, LPL
22positive regulation of cholesterol storageGO:0108869.4APOB, LPL
23response to nutrientGO:0075849.4APOC3, APOA1
24high-density lipoprotein particle assemblyGO:0343809.4APOA2, APOA1, APOE
25high-density lipoprotein particle clearanceGO:0343849.4APOE, APOA1, APOA2
26positive regulation of cholesterol esterificationGO:0108739.4APOA2, APOA1, APOE
27positive regulation of macrophage derived foam cell differentiationGO:0107449.3LPL, APOB
28regulation of Cdc42 protein signal transductionGO:0324899.3APOE, APOA1, APOC3
29negative regulation of inflammatory responseGO:0507289.2APOA1, APOE
30lipoprotein biosynthetic processGO:0421589.2APOB, APOA1, APOE
31receptor-mediated endocytosisGO:0068989.1APOB, APOE
32triglyceride catabolic processGO:0194339.1LPL, APOB, APOC3
33G-protein coupled receptor signaling pathwayGO:0071869.0APOC3, APOA1, APOE
34triglyceride homeostasisGO:0703289.0APOA1, APOC3, LPL
35phospholipid effluxGO:0337008.9APOA2, APOC3, APOA1, APOE
36high-density lipoprotein particle remodelingGO:0343758.9APOA2, APOC3, APOA1, APOE
37reverse cholesterol transportGO:0436918.9APOE, APOA1, APOC3, APOA2
38triglyceride metabolic processGO:0066418.7APOE, APOC3, APOA2, LPL
39response to drugGO:0424938.6APOA1, APOC3, APOA2, LPL
40cholesterol effluxGO:0333448.4APOE, APOA1, APOC3, APOA2, APOB
41cholesterol homeostasisGO:0426328.4APOE, APOA1, APOC3, APOA2, APOB
42cholesterol metabolic processGO:0082038.4APOE, APOA1, APOC3, APOA2, APOB
43lipoprotein metabolic processGO:0421577.6LPL, APOB, APOA2, APOC3, APOA1, APOE
44retinoid metabolic processGO:0015237.6APOE, APOA1, APOC3, APOA2, APOB, LPL
45phototransduction, visible lightGO:0076037.6APOE, APOA1, APOC3, APOA2, APOB, LPL
46small molecule metabolic processGO:0442817.2APOE, APOA1, APOC3, APOA2, APOB, LPL

Molecular functions related to Familial Hypertriglyceridemia according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1apolipoprotein receptor bindingGO:0341909.6APOA2, APOA1
2high-density lipoprotein particle bindingGO:0080359.5APOA2, APOA1
3low-density lipoprotein particle receptor bindingGO:0507509.3APOB, APOE
4beta-amyloid bindingGO:0015409.3APOA1, APOE
5lipid transporter activityGO:0053199.3APOA2, APOE
6high-density lipoprotein particle receptor bindingGO:0706539.2APOA2, APOC3, APOA1
7lipase inhibitor activityGO:0551029.2APOA1, APOC3, APOA2
8cholesterol bindingGO:0154859.2APOA2, APOC3, APOA1
9phosphatidylcholine-sterol O-acyltransferase activator activityGO:0602289.2APOA2, APOA1, APOE
10cholesterol transporter activityGO:0171278.7APOB, APOA2, APOA1, APOE
11heparin bindingGO:0082018.6APOE, APOB, LPL
12phospholipid bindingGO:0055438.2APOE, APOA1, APOC3, APOA2, APOB

Products for genes affiliated with Familial Hypertriglyceridemia

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Familial Hypertriglyceridemia

About this section
4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet