MCID: FML168
MIFTS: 23

Familial Isolated Pituitary Adenoma malady

Categories: Genetic diseases, Rare diseases, Endocrine diseases, Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Familial Isolated Pituitary Adenoma

About this section

Aliases & Descriptions for Familial Isolated Pituitary Adenoma:

Name: Familial Isolated Pituitary Adenoma 45 23 51
Fipa 45 23 51
Familial Isolated Pituitary Adenoma Syndrome 45
 
Pituitary Adenoma, Familial Isolated 65
Multiple Gastrointestinal Atresias 65
Pituitary Adenoma Predisposition 65

Characteristics:

Orphanet epidemiological data:

51
familial isolated pituitary adenoma:
Inheritance: Autosomal dominant; Age of onset: All ages

Classifications:



External Ids:

Orphanet51 314777
ICD10 via Orphanet28 D35.2
UMLS65 C1863340, C2676191

Summaries for Familial Isolated Pituitary Adenoma

About this section
Genetics Home Reference:23 Familial isolated pituitary adenoma (FIPA) is an inherited condition characterized by development of a noncancerous tumor in the pituitary gland (called a pituitary adenoma). The pituitary gland, which is found at the base of the brain, produces hormones that control many important body functions.

MalaCards based summary: Familial Isolated Pituitary Adenoma, also known as fipa, is related to aip-related familial isolated pituitary adenomas and pituitary adenoma, growth hormone-secreting. An important gene associated with Familial Isolated Pituitary Adenoma is AIP (Aryl Hydrocarbon Receptor Interacting Protein), and among its related pathways is . Affiliated tissues include pituitary, brain and prostate.

Related Diseases for Familial Isolated Pituitary Adenoma

About this section

Graphical network of diseases related to Familial Isolated Pituitary Adenoma:



Diseases related to familial isolated pituitary adenoma

Symptoms for Familial Isolated Pituitary Adenoma

About this section

Drugs & Therapeutics for Familial Isolated Pituitary Adenoma

About this section

Drugs for Familial Isolated Pituitary Adenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Hormones11748

Interventional clinical trials:

idNameStatusNCT IDPhase
1Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPARecruitingNCT00461188
2Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene Mutations in AcromegalyRecruitingNCT01902420

Search NIH Clinical Center for Familial Isolated Pituitary Adenoma

Genetic Tests for Familial Isolated Pituitary Adenoma

About this section

Anatomical Context for Familial Isolated Pituitary Adenoma

About this section

MalaCards organs/tissues related to Familial Isolated Pituitary Adenoma:

33
Pituitary, Brain, Prostate, Liver

Animal Models for Familial Isolated Pituitary Adenoma or affiliated genes

About this section

Publications for Familial Isolated Pituitary Adenoma

About this section

Articles related to Familial Isolated Pituitary Adenoma:

(show all 18)
idTitleAuthorsYear
1
Clinical outcomes of women with recurrent or persistent uterine leiomyosarcoma. (25248114)
2014
2
New roles of NCX in glial cells: activation of microglia in ischemia and differentiation of oligodendrocytes. (23224890)
2013
3
Increased urinary frequency: an unusual presentation of Plasmodium falciparum malaria. (22805407)
2012
4
Self organizing molecular field analysis on a series of human 5alpha-reductase inhibitors: unsaturated 3-carboxysteroid. (19716209)
2009
5
ICTAL EEG fast activity in West syndrome: from onset to outcome. (17825076)
2007
6
Gene amplification and protein overexpression of HER-2/neu in human extrahepatic cholangiocarcinoma as detected by chromogenic in situ hybridization and immunohistochemistry: its prognostic implication in node-positive patients. (17322545)
2007
7
Liver penetration of duodenal ulcer. (17205410)
2006
8
The benzophenanthridine alkaloid fagaronine induces erythroleukemic cell differentiation by gene activation. (15971117)
2005
9
Mechanistic and predictive profiling of 5-Fluorouracil resistance in human cancer cells. (15548681)
2004
10
Compartmentalization of integrin alpha6beta4 signaling in lipid rafts. (14517202)
2003
11
Digoxin up-regulates multidrug resistance transporter (MDR1) mRNA and simultaneously down-regulates steroid xenobiotic receptor mRNA. (12788075)
2003
12
Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme. (10684867)
2000
13
Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures. (10448428)
1999
14
Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. (9537820)
1997
15
Involvement of a Ca2+/calmodulin-dependent protein kinase II-associated mechanism in the induction of an outward potassium current by quisqualate. (7953702)
1994
16
Recombinant human mullerian inhibiting substance inhibits human ocular melanoma cell lines in vitro and in vivo. (1531323)
1992
17
Cerebromeningeal pleomorphic xanthoastrocytoma. Report on four cases: clinical, radiologic and pathological features. (Including a case with malignant evolution). (2030826)
1991
18
Clinical importance of prostatic measurements in follow-up of GnRH analogue-treated prostatic carcinoma patients. (2118285)
1990

Variations for Familial Isolated Pituitary Adenoma

About this section

Expression for genes affiliated with Familial Isolated Pituitary Adenoma

About this section
Search GEO for disease gene expression data for Familial Isolated Pituitary Adenoma.

Pathways for genes affiliated with Familial Isolated Pituitary Adenoma

About this section

Pathways related to Familial Isolated Pituitary Adenoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.0

GO Terms for genes affiliated with Familial Isolated Pituitary Adenoma

About this section

Sources for Familial Isolated Pituitary Adenoma

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet