MCID: FML085
MIFTS: 25

Familial Prostate Cancer malady

Cancer diseases, Genetic diseases categories

Summaries for Familial Prostate Cancer

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Sources:
46OMIM, 32MalaCards
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MalaCards: Familial Prostate Cancer, also known as prostate cancer, familial, is related to prostate cancer and prostatitis. An important gene associated with Familial Prostate Cancer is MSR1 (macrophage scavenger receptor 1). The compound n acetylcysteine have been mentioned in the context of this disorder. Affiliated tissues include prostate.

Description from OMIM:46 176807

Aliases & Classifications for Familial Prostate Cancer

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Sources:
42NIH Rare Diseases, 46OMIM, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Genetic diseases


Aliases & Descriptions:

familial prostate cancer 42
prostate cancer, familial 42 46 60
prostate cancer, hereditary 42 46
malignant neoplasm of prostate 60
hereditary prostate cancer 42


Related Diseases for Familial Prostate Cancer

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Familial Prostate Cancer:



Diseases related to familial prostate cancer

Clinical Features for Familial Prostate Cancer

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Sources:
46OMIM
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Clinical features from OMIM:

176807

Drugs & Therapeutics for Familial Prostate Cancer

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Familial Prostate Cancer

Drug clinical trials:

Search ClinicalTrials for Familial Prostate Cancer

Search NIH Clinical Center for Familial Prostate Cancer

Search CenterWatch for Familial Prostate Cancer

Genetic Tests for Familial Prostate Cancer

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Anatomical Context for Familial Prostate Cancer

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Sources:
32MalaCards
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MalaCards organs/tissues related to Familial Prostate Cancer:

32
Prostate

Animal Models for Familial Prostate Cancer or affiliated genes

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Publications for Familial Prostate Cancer

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Genetic Variations for Familial Prostate Cancer

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Sources:
62UniProtKB/Swiss-Prot
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Genetic disease variations for Familial Prostate Cancer:

62 (show all 42)
id Symbol AA change Variation ID SNP ID
1CHEK2p.Arg180CysVAR_019103rs77130927
2CHEK2p.Arg180CysVAR_019103rs77130927
3CHEK2p.Arg181CysVAR_019104rs137853010
4CHEK2p.Arg181CysVAR_019104rs137853010
5CHEK2p.Arg181HisVAR_019105rs121908701
6CHEK2p.Arg181HisVAR_019105rs121908701
7CHEK2p.Glu239LysVAR_019106
8CHEK2p.Glu239LysVAR_019106
9CHEK2p.Glu64LysVAR_019107
10CHEK2p.Glu64LysVAR_019107
11CHEK2p.Arg145ProVAR_019108
12CHEK2p.Arg145ProVAR_019108
13CHEK2p.Gly167ArgVAR_019109
14CHEK2p.Gly167ArgVAR_019109
15CHEK2p.Arg180HisVAR_019110rs137853009
16CHEK2p.Arg180HisVAR_019110rs137853009
17CHEK2p.Ile251PheVAR_019111
18CHEK2p.Ile251PheVAR_019111
19CHEK2p.Arg318HisVAR_019112rs143611747
20CHEK2p.Arg318HisVAR_019112rs143611747
21CHEK2p.Thr323ProVAR_019113
22CHEK2p.Thr323ProVAR_019113
23CHEK2p.Tyr327CysVAR_019114
24CHEK2p.Tyr327CysVAR_019114
25CHEK2p.Thr476LysVAR_019115
26CHEK2p.Thr476LysVAR_019115
27EPHB2p.Arg199HisVAR_032853
28EPHB2p.Arg199HisVAR_032853
29EPHB2p.Ala279SerVAR_032854rs35882952
30EPHB2p.Ala279SerVAR_032854rs35882952
31EPHB2p.Val650AlaVAR_032855rs142173175
32EPHB2p.Val650AlaVAR_032855rs142173175
33EPHB2p.His679AsnVAR_032856
34EPHB2p.His679AsnVAR_032856
35EPHB2p.Met883ValVAR_032857
36EPHB2p.Met883ValVAR_032857
37EPHB2p.Ile909MetVAR_032858
38EPHB2p.Ile909MetVAR_032858
39MXI1p.Glu152AlaVAR_004499
40MXI1p.Glu152AlaVAR_004499
41PTENp.Met134LeuVAR_007469
42PTENp.Met134LeuVAR_007469

Expression for genes affiliated with Familial Prostate Cancer

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Familial Prostate Cancer

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Pathways for genes affiliated with Familial Prostate Cancer

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Compounds for genes affiliated with Familial Prostate Cancer

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Sources:
44Novoseek
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Compounds related to Familial Prostate Cancer according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1n acetylcysteine449.1MSR1, CHEK2

GO Terms for genes affiliated with Familial Prostate Cancer

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Products for genes affiliated with Familial Prostate Cancer

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Familial Prostate Cancer

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet