MCID: FML003
MIFTS: 27

Familial Visceral Amyloidosis malady

Nephrological diseases, Genetic diseases categories

Summaries for Familial Visceral Amyloidosis

About this section
Sources:
63Wikipedia, 46OMIM, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Familial renal amyloidosis (or familial visceral amyloidosis, or hereditary amyloid nephropathy) is a... more...

MalaCards: Familial Visceral Amyloidosis, also known as german type amyloidosis, is related to amyloidosis and apoa1-related familial visceral amyloidosis. An important gene associated with Familial Visceral Amyloidosis is LYZ (lysozyme), and among its related pathways are Platelet degranulation and Packaging Of Telomere Ends. The compounds iohexol and prostacyclin have been mentioned in the context of this disorder. Affiliated tissues include kidney.

Description from OMIM:46 105200

Aliases & Classifications for Familial Visceral Amyloidosis

About this section
Sources:
8Disease Ontology, 42NIH Rare Diseases, 44Novoseek, 60UMLS, 46OMIM
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases
Anatomical: Nephrological diseases


Aliases & Descriptions:

familial visceral amyloidosis 8
german type amyloidosis 8 42
amyloidosis, systemic nonneuropathic 44
amyloidosis systemic nonneuropathic 42
systemic nonneuropathic amyloidosis 8
amyloidosis, familial visceral 60
amyloidosis familial visceral 42
amyloidosis, familial renal 8
amyloidosis familial renal 42
ostertag type amyloidosis 8
amyloidosis viii 42
amyloidosis 8 42


External Ids:

Disease Ontology8 DOID:0050636
OMIM46 105200

Related Diseases for Familial Visceral Amyloidosis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Familial Visceral Amyloidosis:



Diseases related to familial visceral amyloidosis

Clinical Features for Familial Visceral Amyloidosis

About this section
Sources:
46OMIM
See all sources

Clinical features from OMIM:

105200

Drugs & Therapeutics for Familial Visceral Amyloidosis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Familial Visceral Amyloidosis

Drug clinical trials:

Search ClinicalTrials for Familial Visceral Amyloidosis

Search NIH Clinical Center for Familial Visceral Amyloidosis

Search CenterWatch for Familial Visceral Amyloidosis

Genetic Tests for Familial Visceral Amyloidosis

About this section

Anatomical Context for Familial Visceral Amyloidosis

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Familial Visceral Amyloidosis:

32
Kidney

Animal Models for Familial Visceral Amyloidosis or affiliated genes

About this section

Publications for Familial Visceral Amyloidosis

About this section

Genetic Variations for Familial Visceral Amyloidosis

About this section

Expression for genes affiliated with Familial Visceral Amyloidosis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Familial Visceral Amyloidosis

Search GEO for disease gene expression data for Familial Visceral Amyloidosis.

Pathways for genes affiliated with Familial Visceral Amyloidosis

About this section
Sources:
53Reactome
See all sources

Pathways related to Familial Visceral Amyloidosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.1FGA, APOA1
2
Hide members
9.1FGA, APOA1
38.5LYZ, FGA, APOA1

Compounds for genes affiliated with Familial Visceral Amyloidosis

About this section
Sources:
44Novoseek, 11DrugBank, 49PharmGKB, 28IUPHAR, 24HMDB
See all sources

Compounds related to Familial Visceral Amyloidosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1iohexol449.3FGA, APOA1
2prostacyclin449.2FGA, APOA1
3Alpha-D-Mannose119.1LYZ, FGA
4acetylcholine44 49 28 11 2413.1FGA, APOA1
5nacl449.0FGA, LYZ
6aspirin44 49 28 2412.0FGA, APOA1
7fibrinogen448.8FGA, APOA1

GO Terms for genes affiliated with Familial Visceral Amyloidosis

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Familial Visceral Amyloidosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.5LYZ, FGA, APOA1
2extracellular spaceGO:0056158.2LYZ, FGA, APOA1

Biological processes related to Familial Visceral Amyloidosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet activationGO:0301689.1FGA, APOA1
2platelet degranulationGO:0025768.8FGA, APOA1

Products for genes affiliated with Familial Visceral Amyloidosis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Familial Visceral Amyloidosis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet