MCID: FNC030
MIFTS: 13

Fanconi Anemia, Complementation Group G malady

Summaries for Fanconi Anemia, Complementation Group G

Sources:
47OMIM, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Fanconi Anemia, Complementation Group G An important gene associated with Fanconi Anemia, Complementation Group G is FANCG (Fanconi anemia, complementation group G). Affiliated tissues include bone marrow, breast and b cells.

Description from OMIM:47 614082

Aliases & Classifications for Fanconi Anemia, Complementation Group G

Sources:
47OMIM
See all sources

Aliases & Descriptions:

fanconi anemia, complementation group g 47


Related Diseases for Fanconi Anemia, Complementation Group G

Clinical Features for Fanconi Anemia, Complementation Group G

Sources:
47OMIM
See all sources

Clinical features from OMIM:

614082

Drugs & Therapeutics for Fanconi Anemia, Complementation Group G

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Fanconi Anemia, Complementation Group G

Drug clinical trials:

Search ClinicalTrials for Fanconi Anemia, Complementation Group G

Search NIH Clinical Center for Fanconi Anemia, Complementation Group G

Search CenterWatch for Fanconi Anemia, Complementation Group G

Genetic Tests for Fanconi Anemia, Complementation Group G

Anatomical Context for Fanconi Anemia, Complementation Group G

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Fanconi Anemia, Complementation Group G:

33
Bone marrow, Breast, B cells

Animal Models for Fanconi Anemia, Complementation Group G or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Fanconi Anemia, Complementation Group G

Sources:
51PubMed
See all sources

Articles related to Fanconi Anemia, Complementation Group G:

(show all 42)
idTitleAuthorsYear
1
Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein. (24170812)
2013
2
Human Fanconi Anemia Complementation Group A Protein Stimulates the 5' Flap Endonuclease Activity of FEN1. (24349332)
2013
3
Silencing of fanconi anemia complementation group f exhibits potent chemosensitization of mitomycin C activity in breast cancer cells. (24155758)
2013
4
Prevalence of FA-D2 Rare Complementation Group of Fanconi Anemia in Serbia. (24317781)
2013
5
Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded forms. (22194614)
2012
6
Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross- link repair. (22396592)
2012
7
Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction. (19861535)
2009
8
Identification and characterization of mutations in FANCL gene: a second case of Fanconi anemia belonging to FA-L complementation group. (19405097)
2009
9
Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M. (19423727)
2009
10
Validation of Fanconi anemia complementation Group A assignment using molecular analysis. (19367192)
2009
11
Identification of the Fanconi anemia complementation group I gene, FANCI. (17452773)
2007
12
Inducibility of nuclear Rad51 foci after DNA damage distinguishes all Fanconi anemia complementation groups from D1/BRCA2. (16154163)
2006
13
Cellular characterization of cells from the Fanconi anemia complementation group, FA-D1/BRCA2. (16920162)
2006
14
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. (16116422)
2005
15
Germ line Fanconi anemia complementation group C mutations and pancreatic cancer. (15695377)
2005
16
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J. (16116423)
2005
17
Phosphorylation of fanconi anemia (FA) complementation group G protein, FANCG, at serine 7 is important for function of the FA pathway. (15299017)
2004
18
X-linked inheritance of Fanconi anemia complementation group B. (15502827)
2004
19
Fanconi anemia complementation group A cells are hypersensitive to chromium(VI)-induced toxicity. (12426130)
2002
20
The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality. (11520787)
2001
21
Functional analysis of the putative peroxidase domain of FANCA, the Fanconi anemia complementation group A protein. (11161829)
2001
22
Function of the Fanconi anemia pathway in Fanconi anemia complementation group F and D1 cells. (11750104)
2001
23
Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumor necrosis factor-alpha, and double-stranded RNA. (11238103)
2001
24
Association of complementation group and mutation type with clinical outcome in fanconi anemia. European Fanconi Anemia Research Group. (11110674)
2000
25
Isolation of a cDNA representing the Fanconi anemia complementation group E gene. (11001585)
2000
26
Localization of the Fanconi anemia complementation group D gene to a 200-kb region on chromosome 3p25.3. (10762542)
2000
27
Fanconi anemia, complementation group A, cells are defective in ability to produce incisions at sites of psoralen interstrand cross-links. (10753211)
2000
28
Complementation analysis in Fanconi anemia: assignment of the reference FA-H patient to group A. (10936108)
2000
29
A deficiency in a 230 kDa DNA repair protein in fanconi anemia complementation group A cells is corrected by the FANCA cDNA. (10469633)
1999
30
SNX5, a new member of the sorting nexin family, binds to the Fanconi anemia complementation group A protein. (10600472)
1999
31
Intracellular localization of the Fanconi anemia complementation group A protein. (10364463)
1999
32
The Fanconi anemia complementation group A protein contains a peroxidase domain. (9608546)
1998
33
MxA overexpression reveals a common genetic link in four Fanconi anemia complementation groups. (9389754)
1997
34
Fanconi anemia complementation group E: clinical and cytogenetic data of the first patient. (9147877)
1996
35
Clinical variability of Fanconi anemia (type C) results from expression of an amino terminal truncated Fanconi anemia complementation group C polypeptide with partial activity. (8639804)
1996
36
The Fanconi anemia complementation group C protein corrects DNA interstrand cross-link-specific apoptosis in HSC536N cells. (8822951)
1996
37
Correction of the spontaneous and DEB-induced chromosomal aberrations in Fanconi anemia cells of the FA(C) complementation group by the FACC gene. (8978774)
1996
38
A damage-recognition protein which binds to DNA containing interstrand cross-links is absent or defective in Fanconi anemia, complementation group A, cells. (8414972)
1993
39
Defective DNA endonuclease activities in Fanconi's anemia cells, complementation groups A and B. (1376436)
1992
40
Mutagenic response of Fanconi's anemia cells from a defined complementation group after treatment with photoactivated bifunctional psoralens. (2159378)
1990
41
Two complementation groups of Fanconi's anemia differ in their phenotypic response to a DNA-crosslinking treatment. (3804331)
1987
42
The fate of 8-methoxypsoralen-photoinduced DNA interstrand crosslinks in Fanconi's anemia cells of defined genetic complementation groups. (3670329)
1987

Genetic Variations for Fanconi Anemia, Complementation Group G

Sources:
63UniProtKB/Swiss-Prot
See all sources

Genetic disease variations for Fanconi Anemia, Complementation Group G:

63
id Symbol AA change Variation SNP ID
1FANCGp.Leu71ProVAR_017495

Expression for genes affiliated with Fanconi Anemia, Complementation Group G

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Fanconi Anemia, Complementation Group G

Search GEO for disease gene expression data for Fanconi Anemia, Complementation Group G.

Pathways for genes affiliated with Fanconi Anemia, Complementation Group G

Compounds for genes affiliated with Fanconi Anemia, Complementation Group G

GO Terms for genes affiliated with Fanconi Anemia, Complementation Group G

Products for genes affiliated with Fanconi Anemia, Complementation Group G

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Fanconi Anemia, Complementation Group G

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet