MCID: FNC004
MIFTS: 49

Fanconi Syndrome malady

Categories: Rare diseases, Nephrological diseases

Aliases & Classifications for Fanconi Syndrome

Aliases & Descriptions for Fanconi Syndrome:

Name: Fanconi Syndrome 12 50 29 42 14 69
De Toni-Fanconi Syndrome 12 50
Adult Fanconi Syndrome 12 69
Cystinosis, Infantile Nephropathic 69
Infantile Nephropathic Cystinosis 12
De Toni-Debre-Fanconi Syndrome 69
Congenital Fanconi Syndrome 12
Toni-Debre-Fanconi Syndrome 50
Fanconi-De Toni Syndrome 12
Fanconi-De-Toni Syndrome 12
Fanconi-Bickel Syndrome 69
Detoni Fanconi Syndrome 12
Lignac-Fanconi Syndrome 12
Adult Fanconi Anemia 12
Fanconi Anemia 69

Classifications:



External Ids:

Disease Ontology 12 DOID:1062
MeSH 42 D005198
NCIt 47 C3034 C4377

Summaries for Fanconi Syndrome

Disease Ontology : 12 A renal tubular transport disease of the proximal renal tubes characterized by glucosuria, phosphaturia, generalized aminoaciduria and HCO3 wasting.

MalaCards based summary : Fanconi Syndrome, also known as de toni-fanconi syndrome, is related to hypophosphatemic rickets and interstitial nephritis. An important gene associated with Fanconi Syndrome is SLC34A1 (Solute Carrier Family 34 Member 1), and among its related pathways/superpathways are HIF1Alpha Pathway and Hepatic ABC Transporters. The drugs Acetylcysteine and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and bone, and related phenotypes are growth/size/body region and homeostasis/metabolism

Wikipedia : 71 Fanconi syndrome or Fanconi\'s syndrome (English /fɑːnˈkoʊni/, /fæn-/) is a syndrome of inadequate... more...

Related Diseases for Fanconi Syndrome

Diseases in the Fanconi Syndrome family:

Primary Fanconi Syndrome

Diseases related to Fanconi Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
id Related Disease Score Top Affiliating Genes
1 hypophosphatemic rickets 29.4 CLCN5 CUBN LRP2 OCRL
2 interstitial nephritis 27.5 ALAD CLCN5 CTNS CUBN EHHADH HNF4A
3 primary fanconi syndrome 12.1
4 acquired monoclonal ig light chain-associated fanconi syndrome 11.7
5 cystinosis 11.2
6 dent disease 11.1
7 proximal renal tubular acidosis 11.1
8 fanconi-bickel syndrome 11.0
9 lowe syndrome 10.9
10 fanconi renotubular syndrome 4, with maturity-onset diabetes of the young 10.9
11 fanconi renotubular syndrome 1 10.8
12 dent disease 2 10.7
13 adult-onset still's disease 10.6
14 wissler's syndrome 10.6
15 cystinosis, nephropathic 10.6
16 progeria variant syndrome ruvalcaba type 10.2 EHHADH SLC34A1
17 osteomalacia 10.2
18 nephronophthisis 16 10.2 CUBN EHHADH
19 waardenburg syndrome, type 4b 10.1 PTH SLC34A1
20 joubert syndrome 9 10.1 PTH SLC34A1
21 coffin-lowry syndrome 10.1 PTH SLC34A1
22 hepatitis 10.1
23 malignant biphasic mesothelioma 10.1 CLCN5 OCRL
24 gastric antral vascular ectasia 10.0 PTH SLC34A1
25 weill-marchesani syndrome 10.0 PTH SLC34A1
26 star syndrome 10.0 CLCN5 LRP2 OCRL
27 rickets 10.0
28 opportunistic bacterial infectious disease 10.0 CLCN5 PTH SLC34A1
29 acute inferolateral myocardial infarction 10.0 CTNS CUBN LRP2
30 allergic urticaria 10.0 CLCN5 PTH SLC34A1
31 renal tubular acidosis 10.0
32 multiple myeloma 10.0
33 hepatitis b 10.0
34 prostate cancer, hereditary, x-linked 2 10.0 CLCN5 SLC34A1
35 diabetes insipidus 10.0
36 calcinosis 9.9 CLCN5 LRP2 PTH
37 ectopic cushing syndrome 9.9 PTH SLC2A2
38 amyloidosis bronchopulmonary 9.9 CLCN5 EHHADH HNF4A OCRL SLC34A1
39 primary biliary cirrhosis 9.8
40 uveitis 9.8
41 aminoaciduria 9.8
42 hyperparathyroidism 9.8
43 cystinuria 9.7
44 nephrotic syndrome 9.7
45 kearns-sayre syndrome 9.7
46 histiocytosis 9.7
47 myopathy 9.7
48 kidney disease 9.7
49 hemoglobinuria 9.6
50 acquired immunodeficiency syndrome 9.6

Graphical network of the top 20 diseases related to Fanconi Syndrome:



Diseases related to Fanconi Syndrome

Symptoms & Phenotypes for Fanconi Syndrome

MGI Mouse Phenotypes related to Fanconi Syndrome:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.85 CLCN5 CUBN EHHADH HNF4A LRP2 NDUFAF6
2 homeostasis/metabolism MP:0005376 9.65 HNF4A LRP2 OCRL PTH SLC2A2 SLC34A1
3 renal/urinary system MP:0005367 9.1 CLCN5 CTNS CUBN LRP2 OCRL SLC34A1

Drugs & Therapeutics for Fanconi Syndrome

Drugs for Fanconi Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 123)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
2 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
3 Protective Agents Phase 4,Phase 2,Phase 1
4 Antiviral Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
5 N-monoacetylcystine Phase 4
6 Expectorants Phase 4
7 Antidotes Phase 4
8 Respiratory System Agents Phase 4
9 Antioxidants Phase 4,Phase 1
10 cysteine Nutraceutical Phase 4
11
Cyclophosphamide Approved, Investigational Phase 2, Phase 3, Phase 1, Early Phase 1 50-18-0, 6055-19-2 2907
12
Fludarabine Approved Phase 2, Phase 3, Phase 1, Early Phase 1 21679-14-1, 75607-67-9 30751
13
Vidarabine Approved Phase 2, Phase 3,Phase 1,Early Phase 1 24356-66-9 32326 21704
14
Busulfan Approved, Investigational Phase 2, Phase 3,Phase 1,Early Phase 1 55-98-1 2478
15
alemtuzumab Approved, Investigational Phase 2, Phase 3,Phase 1 216503-57-0
16
Iron Approved Phase 3,Phase 2 7439-89-6 23925
17
Mycophenolic acid Approved Phase 2, Phase 3,Phase 1 24280-93-1 446541
18
Mycophenolate mofetil Approved, Investigational Phase 2, Phase 3,Phase 1 128794-94-5 5281078
19
Miconazole Approved, Investigational, Vet_approved Phase 2, Phase 3,Phase 1 22916-47-8 4189
20
Cysteamine Approved, Investigational Phase 3,Phase 1,Phase 2 60-23-1 6058
21
Deferasirox Approved, Investigational Phase 3,Phase 2 201530-41-8 5493381
22
Everolimus Approved Phase 2, Phase 3 159351-69-6 6442177
23
Sirolimus Approved, Investigational Phase 2, Phase 3 53123-88-9 5284616 6436030 46835353
24 Alkylating Agents Phase 2, Phase 3, Phase 1, Early Phase 1
25 Immunosuppressive Agents Phase 2, Phase 3, Phase 1, Early Phase 1
26 Antimetabolites Phase 2, Phase 3, Phase 1, Early Phase 1
27 Antimetabolites, Antineoplastic Phase 2, Phase 3, Phase 1, Early Phase 1
28 Antirheumatic Agents Phase 2, Phase 3, Phase 1, Early Phase 1
29 Antineoplastic Agents, Alkylating Phase 2, Phase 3, Phase 1, Early Phase 1
30 Chelating Agents Phase 3,Phase 2
31 Anti-Bacterial Agents Phase 2, Phase 3,Phase 1
32 Antifungal Agents Phase 2, Phase 3,Phase 1
33 Iron Chelating Agents Phase 3,Phase 2
34 Antibiotics, Antitubercular Phase 2, Phase 3,Phase 1
35
Melphalan Approved Phase 2,Phase 1 148-82-3 4053 460612
36
Prednisolone Approved, Vet_approved Phase 2,Phase 1 50-24-8 5755
37
Lenograstim Approved Phase 1, Phase 2 135968-09-1
38
Methylprednisolone Approved, Vet_approved Phase 2,Phase 1 83-43-2 6741
39
Dopamine Approved Phase 2 51-61-6, 62-31-7 681
40
Cyclosporine Approved, Investigational, Vet_approved Phase 1, Phase 2 79217-60-0, 59865-13-3 5284373 6435893
41
Deferoxamine Approved, Investigational Phase 2 70-51-9 2973
42
Bortezomib Approved, Investigational Phase 2 179324-69-7 387447 93860
43
Methamphetamine Approved, Illicit Phase 2 537-46-2 10836
44
Deferiprone Approved Phase 2 30652-11-0 2972
45
Tacrolimus Approved, Investigational Phase 2,Phase 1 104987-11-3 445643 439492
46
Thiotepa Approved Phase 2,Phase 1 52-24-4 5453
47
Phenytoin Approved, Vet_approved Phase 1, Phase 2 57-41-0 1775
48
Fosphenytoin Approved Phase 1, Phase 2 93390-81-9 56339
49
Danazol Approved Phase 1, Phase 2 17230-88-5 28417
50 Prednisolone acetate Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 88)
id Name Status NCT ID Phase
1 Fanconi Syndrome Due to ARVs in HIV-Infected Persons Completed NCT00499187 Phase 4
2 N Acetyl Cysteine for Cystinosis Patients Completed NCT01614431 Phase 4
3 Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases Unknown status NCT01019876 Phase 2, Phase 3
4 Phase 3 Study of Cysteamine Bitartrate Delayed-release (RP103) Compared to Cystagon® in Patients With Cystinosis Completed NCT01000961 Phase 3
5 Safety/Effectiveness Study of Cysteamine Bitartrate Delayed-release Capsules (RP103) in Cysteamine Treatment Naive Patients With Cystinosis Completed NCT01744782 Phase 3
6 A Study Assessing the Efficacy and Safety of Deferasirox in Patients With Transfusion-dependent Iron Overload Completed NCT00171821 Phase 3
7 TBI Dose De-escalation for Fanconi Anemia Recruiting NCT00352976 Phase 2, Phase 3
8 Long-Term Safety Follow-up Study of Cysteamine Bitartrate Delayed-release Capsules (RP103) Active, not recruiting NCT01197378 Phase 3
9 Open-Label, Safety and Superior Effectiveness Study of Cysteamine Bitartrate Delayed-Release Capsules (RP103) in Cystinosis Active, not recruiting NCT01733316 Phase 3
10 Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases Unknown status NCT00084695 Phase 2
11 Multicenter Transplant Study for Fanconi Anemia Completed NCT01082133 Phase 2
12 Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100 Completed NCT00479115 Phase 1, Phase 2
13 Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia Completed NCT00005898 Phase 1, Phase 2
14 Pilot Study of Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of RP103 Compared to Cystagon® in Patients With Cystinosis Completed NCT00872729 Phase 1, Phase 2
15 Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias Completed NCT00061763 Phase 2
16 Medical Treatment for Diamond Blackfan Anemia Completed NCT00001749 Phase 2
17 Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes Completed NCT00004787 Phase 2
18 Bortezomib Followed by High-Dose Melphalan and Bortezomib as Conditioning Regimen for Tandem Stem Cell Transplants Completed NCT00307086 Phase 2
19 Busulfan, Antithymocyte Globulin, and Fludarabine Followed By a Donor Stem Cell Transplant in Treating Young Patients With Blood Disorders, Bone Marrow Disorders, Chronic Myelogenous Leukemia in First Chronic Phase, or Acute Myeloid Leukemia in First Remi Completed NCT00305708 Phase 1, Phase 2
20 Cord Blood Stem Cell Transplantation Study (COBLT) Completed NCT00000603 Phase 2
21 Cysteamine Eye Drops to Treat Corneal Crystals in Cystinosis Completed NCT00001213 Phase 2
22 A Protocol to Allow Treatment With ICL670 for Patients With or at Risk of Life-threatening Complications of Transfusional Iron Overload Who Are Unable to Tolerate Other Iron Chelators Because of Documented Severe Toxicity Completed NCT01044186 Phase 2
23 Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia Recruiting NCT00258427 Phase 2
24 Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia Recruiting NCT00630253 Phase 1, Phase 2
25 Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and Plerixafor Recruiting NCT02678533 Phase 1, Phase 2
26 Clinical Phase II Trial to Evaluate CD34+ Cells Mobilization and Collection in Patients With Fanconi Anemia for Subsequent Transduction With a Lentiviral Vector Carring FANCA Gene. FANCOSTEM-1 Recruiting NCT02931071 Phase 2
27 HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy Recruiting NCT02143830 Phase 2
28 Lentiviral-mediated Gene Therapy of Fanconi Anemia Patients Subtype A Recruiting NCT03157804 Phase 1, Phase 2
29 Talazoparib Beyond BRCA (TBB) Trial Recruiting NCT02401347 Phase 2
30 CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant Recruiting NCT01049854 Phase 2
31 A Study of LY2606368 (Prexasertib) in Patients With Solid Tumors With Replicative Stress or Homologous Repair Deficiency Recruiting NCT02873975 Phase 2
32 Hematopoietic Stem Cell Transplant for Fanconi Anemia Active, not recruiting NCT01071239 Phase 2
33 Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine Active, not recruiting NCT00987480 Phase 2
34 Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant, Mycophenolate Mofetil, and Cyclosporine in Treating Patients With Fanconi Anemia Active, not recruiting NCT00453388 Phase 2
35 Carfilzomib + High Dose Melphalan as Preparative Regimen for Autologous Hematopoietic Stem Cell Transplantation Active, not recruiting NCT01690143 Phase 1, Phase 2
36 Phase II Study of BMN 673 Active, not recruiting NCT02286687 Phase 2
37 Safety and Efficacy Trial of Danazol in Patients With Fanconi Anemia or Dyskeratosis Congenita Terminated NCT01001598 Phase 1, Phase 2
38 Stem Cell Transplantation for Fanconi Anemia Terminated NCT00167206 Phase 1, Phase 2
39 Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi Anemia Terminated NCT00590460 Phase 1, Phase 2
40 Stem Cell Transplant for Hematologic Diseases Terminated NCT00058825 Phase 1, Phase 2
41 Double Cord Blood Transplantation Terminated NCT00801931 Phase 1, Phase 2
42 Phase I Study of Amifostine in Patients With Bone Marrow Failure Related to Fanconi's Anemia Unknown status NCT00006127 Phase 1
43 Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia Unknown status NCT00005896 Phase 1
44 Oxandrolone for the Treatment of Bone Marrow Aplasia in Fanconi Anemia Completed NCT00243399 Phase 1
45 Cyclophosphamide in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Fanconi's Anemia Completed NCT00317876 Phase 1
46 Gene Therapy for the Treatment of Fanconi's Anemia Type C Completed NCT00001399 Phase 1
47 Bone Marrow Cell Gene Transfer in Individuals With Fanconi Anemia Completed NCT00272857 Phase 1
48 Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed by Unrelated Donor Stem Cell Transplant in Treating Patients With Fanconi Anemia Completed NCT00093743 Phase 1
49 Quercetin in Children With Fanconi Anemia; a Pilot Study Recruiting NCT01720147 Phase 1
50 Gene Therapy for Fanconi Anemia Recruiting NCT01331018 Phase 1

Search NIH Clinical Center for Fanconi Syndrome

Cochrane evidence based reviews: fanconi syndrome

Genetic Tests for Fanconi Syndrome

Genetic tests related to Fanconi Syndrome:

id Genetic test Affiliating Genes
1 Fanconi Syndrome 29

Anatomical Context for Fanconi Syndrome

MalaCards organs/tissues related to Fanconi Syndrome:

39
Kidney, Liver, Bone, Lung, Thyroid, Cortex

Publications for Fanconi Syndrome

Articles related to Fanconi Syndrome:

(show top 50) (show all 473)
id Title Authors Year
1
Intraretinal Crystals in Nephopathic Cystinosis and Fanconi Syndrome. ( 28278342 )
2017
2
Endocytic receptor LRP2/megalin-of holoprosencephaly and renal Fanconi syndrome. ( 28497274 )
2017
3
The renal Fanconi syndrome in cystinosis: pathogenic insights and therapeutic perspectives. ( 27990015 )
2017
4
Successful treatment of proximal renal tubular acidosis and Fanconi syndrome with vitamin D replacement. ( 27424705 )
2016
5
Drug-induced Fanconi syndrome associated with fumaric acid esters treatment for psoriasis: a case series. ( 26798466 )
2016
6
Fanconi Anemia and Fanconi Syndrome: Time to Correct the Misnomers. ( 27571122 )
2016
7
Topiramate as a rare cause of reversible Fanconi syndrome and acute kidney injury: a case report and literature review. ( 26908388 )
2016
8
Fanconi Syndrome: A Rare Initial Presentation of Acute Lymphoblastic Leukemia. ( 27408343 )
2016
9
Outcomes of renal proximal tubular dysfunctions with Fanconi syndrome caused by sodium valproate. ( 26896192 )
2016
10
Misdiagnosis of Bone Metastasis Cancer After Using Adefovir Dipivoxi in a Hepatitis B Patient with Fanconi Syndrome. ( 27408428 )
2016
11
Wissler-Fanconi syndrome and related diagnoses: a case report. ( 27843372 )
2016
12
SjAPgren's syndrome complicated with Fanconi syndrome and Hashimoto's thyroiditis: Case report and literature review. ( 26966155 )
2016
13
MELAS Syndrome and Kidney Disease Without Fanconi Syndrome or Proteinuria: A Case Report. ( 27683045 )
2016
14
Renal Fanconi Syndrome Is Caused by a Mistargeting-Based Mitochondriopathy. ( 27160910 )
2016
15
Tubulointerstitial nephritis and Fanconi syndrome in a patient with primary SjAPgren's syndrome accompanied by antimitochondrial antibodies: A case report and review of the literature. ( 27142563 )
2016
16
Bilineal Acute Leukemia Associated With Fanconi Syndrome: The First Case Report. ( 27617066 )
2016
17
Fanconi syndrome due to light chain proximal tubulopathy in a patient with multiple myeloma. ( 27424703 )
2016
18
Serum FGF23 levels may not be associated with serum phosphate and 1,25-dihydroxyvitamin D levels in patients with Fanconi syndrome-induced hypophosphatemia. ( 27679714 )
2016
19
Current anti-myeloma therapies in renal manifestations of monoclonal light chain-associated Fanconi syndrome: a retrospective series of 49 patients. ( 27435002 )
2016
20
Renal Fanconi Syndrome and Hypophosphatemic Rickets in the Absence of Xenotropic and Polytropic Retroviral Receptor in the Nephron. ( 27799484 )
2016
21
Fanconi Syndrome Secondary to Deferasirox in Diamond-Blackfan Anemia: Case Series and Recommendations for Early Diagnosis. ( 27082377 )
2016
22
Fanconi syndrome induced by tenofovir: A case report. ( 27424704 )
2016
23
A Tenofovir-induced Fanconi syndrome in a patient with chronic hepatitis B monoinfection. ( 26845606 )
2016
24
Reporting cases of Fanconi syndrome in dogs in the UK. ( 27179094 )
2016
25
Fanconi Syndrome Associated with Hyponatremia in Two Patients with Legionella Pneumonia. ( 27904113 )
2016
26
Progressive myoclonic epilepsy with Fanconi syndrome. ( 27293772 )
2016
27
Fanconi syndrome in paraquat poisoning. ( 27728607 )
2016
28
Acadian variant of Fanconi syndrome is caused by mitochondrial respiratory chain complex I deficiency due to a non-coding mutation in complex I assembly factor NDUFAF6. ( 27466185 )
2016
29
Tenofovir-Induced Fanconi Syndrome Presenting as Hypokalemic Periodic Paralysis. ( 27574926 )
2016
30
Pathologic Femoral Neck Fracture Due to Fanconi Syndrome Induced by Adefovir Dipivoxil Therapy for Hepatitis B. ( 27247753 )
2016
31
Infantile nephropathic cystinosis with incomplete fanconi syndrome, hypothyroidism, hydro-uretero-nephrosis, and megacystis. ( 27215258 )
2016
32
Hepatocyte Nuclear Factor-4 Alfa Mutation Associated with Hyperinsulinaemic Hypoglycaemia and Atypical Renal Fanconi Syndrome: Expanding the Clinical Phenotype. ( 27245055 )
2016
33
The reduced expression of proximal tubular transporters in acquired Fanconi syndrome with I_ light chain deposition. ( 26141649 )
2015
34
Fanconi syndrome due to prolonged use of low-dose adefovir. ( 26110001 )
2015
35
Low-dose adefovir dipivoxil may induce Fanconi syndrome: clinical characteristics and long-term follow-up for Chinese patients. ( 25814481 )
2015
36
Nephropathic Cystinosis Presenting as Renal Fanconi Syndrome without Glycosuria. ( 25954677 )
2015
37
1266: DEVELOPMENT OF FANCONI SYNDROME AFTER ADDITION OF LEDIPASVIR/SOFOSBUVIR IN A PATIENT ON TENOFOVIR. ( 26570927 )
2015
38
Hypokalemic paralysis secondary to tenofovir induced fanconi syndrome. ( 26692618 )
2015
39
Successful treatment with glucocorticoid for secondary Fanconi syndrome caused by sarcoidosis. ( 25698227 )
2015
40
Dental findings in Brazilian patients with Fanconi syndrome. ( 26147214 )
2015
41
Acute renal failure secondary to interstitial acute nephritis and Fanconi syndrome for metamizole and gemfibrozil. ( 26306948 )
2015
42
Transient renal Fanconi syndrome in a Chihuahua exposed to Chinese chicken jerky treats. ( 25966748 )
2015
43
Tenofovir-associated Fanconi syndrome and nephrotic syndrome in a patient with chronic hepatitis B monoinfection. ( 25645518 )
2015
44
Fanconi syndrome induced by vemurafenib: a new renal adverse event. ( 25494458 )
2015
45
A case of severe osteomalacia caused by Tubulointerstitial nephritis with Fanconi syndrome in asymptomotic primary biliary cirrhosis. ( 26554665 )
2015
46
A single-center case series of eight patients with the rare plasma cell dyscrasia of acquired Fanconi syndrome secondary to monoclonal gammopathy. ( 25791236 )
2015
47
Acquired Fanconi syndrome in a dog exposed to jerky treats in Japan. ( 26062568 )
2015
48
A pharmacogenetic candidate gene study of tenofovir-associated Fanconi syndrome. ( 25485598 )
2015
49
Primary hyperparathyroidism and multiple myeloma complicated by Fanconi syndrome: A fortuitous association? ( 25540875 )
2015
50
Nonconvulsive Status Epilepticus in Elderly Patients Receiving SSRIs; Euglycemic Diabetic Ketoacidosis Associated with Canagliflozin Use in a Type 1 Diabetic Patient; Duloxetine-Induced Galactorrhea; Canagliflozin-Associated Severe Hypercalcemia and Hypernatremia; Vemurafenib-Induced Fanconi Syndrome. ( 26912914 )
2015

Variations for Fanconi Syndrome

Expression for Fanconi Syndrome

Search GEO for disease gene expression data for Fanconi Syndrome.

Pathways for Fanconi Syndrome

Pathways related to Fanconi Syndrome according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.89 HNF4A SLC2A2
2
Show member pathways
10.89 CLCN5 HNF4A SLC2A2
3 10.6 HNF4A SLC2A2

GO Terms for Fanconi Syndrome

Cellular components related to Fanconi Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 apical plasma membrane GO:0016324 9.67 CUBN LRP2 SLC2A2 SLC34A1
2 endosome GO:0005768 9.65 CLCN5 CUBN LRP2 OCRL SLC34A1
3 lysosomal membrane GO:0005765 9.62 CLCN5 CTNS CUBN LRP2
4 apical part of cell GO:0045177 9.58 CLCN5 CUBN LRP2
5 clathrin-coated pit GO:0005905 9.33 CUBN LRP2 OCRL
6 brush border membrane GO:0031526 9.13 CUBN LRP2 SLC34A1
7 brush border GO:0005903 8.92 CUBN LRP2 SLC2A2 SLC34A1

Biological processes related to Fanconi Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 lipid metabolic process GO:0006629 9.65 CUBN EHHADH HNF4A LRP2 OCRL
2 lipoprotein transport GO:0042953 9.4 CUBN LRP2
3 vitamin D metabolic process GO:0042359 9.37 CUBN LRP2
4 response to mercury ion GO:0046689 9.32 ALAD SLC34A1
5 response to parathyroid hormone GO:0071107 9.16 PTH SLC34A1
6 response to cadmium ion GO:0046686 9.13 ALAD PTH SLC34A1
7 response to lead ion GO:0010288 8.8 ALAD PTH SLC34A1

Sources for Fanconi Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....