MCID: FSC004
MIFTS: 44

Fasciitis malady

Summaries for Fasciitis

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 In medicine, fasciitis /ˌfæʃiˈaɪtɪs/ refers to an inflammation of the fascia, which is the... more...

MalaCards: Fasciitis is related to necrotizing fasciitis and plantar fasciitis. An important gene associated with Fasciitis is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways is Regulation of Wnt-mediated beta catenin signaling and target gene transcription. The compounds policosanol and alpha-hydroxybutyrate have been mentioned in the context of this disorder. Related mouse phenotypes are cardiovascular system and mortality/aging.

Aliases & Classifications for Fasciitis

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 27ICD9CM, 40NCIt, 35MeSH, 57SNOMED-CT
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Aliases & Descriptions:

fasciitis 8 10 45 61


External Ids:

Disease Ontology8 DOID:9598
ICD9CM27 729.4
SNOMED-CT57 203123000, 36948007
NCIt40 C50559
MeSH35 D005208

Related Diseases for Fasciitis

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Fasciitis:



Diseases related to fasciitis

Clinical Features for Fasciitis

Drugs & Therapeutics for Fasciitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Fasciitis

Drug clinical trials:

Search ClinicalTrials for Fasciitis

Search NIH Clinical Center for Fasciitis

Search CenterWatch for Fasciitis

Genetic Tests for Fasciitis

Anatomical Context for Fasciitis

Animal Models for Fasciitis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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Publications for Fasciitis

Sources:
51PubMed
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Articles related to Fasciitis:

(show top 50)    (show all 1542)
idTitleAuthorsYear
1
Nodular fasciitis over the anterior wall of the maxillary sinus: a case report and review of the literature. (23217546)
2013
2
Facial necrotizing fasciitis. (23859680)
2013
3
Necrotizing fasciitis: a case report of a premature infant with necrotizing enterocolitis. (23276506)
2013
4
"Synchronous" multifocal necrotizing fasciitis. (24063873)
2013
5
Severe aplastic anemia associated with eosinophilic fasciitis: report of 4 cases and review of the literature. (23429351)
2013
6
Monomicrobial Pseudomonas necrotizing fasciitis: a case of infection by two strains and a review of 37 cases in the literature. (22126406)
2012
7
Use of pulsed radio frequency energy in the effective treatment of recalcitrant plantar fasciitis: Six case histories. (22265451)
2012
8
Necrotizing fasciitis of thigh associated with Escherichia coli bacteremia in a patient on chronic hemodialysis. (22304536)
2012
9
The value of frozen section biopsy in diagnosing necrotizing fasciitis: proposal of a new grading system. (22100150)
2012
10
A fatal case of necrotizing Aeromonas schubertii fasciitis after penetrating injury. (21247722)
2012
11
Intra-articular nodular fasciitis of the knee: a rare cause of recurrent hemarthrosis. (21431289)
2012
12
Necrotizing fasciitis: classification, diagnosis, and management. (22491537)
2012
13
Design and validation of a dynamic stretch splint for plantar fasciitis. (22118855)
2012
14
Necrotizing fasciitis of the breast and axillary regions. (23131384)
2012
15
Acute cervicofacial necrotizing fasciitis: three clinical cases and a review of the current literature. (22313983)
2012
16
Transfer status: a risk factor for mortality in patients with necrotizing fasciitis. (21783216)
2011
17
Plantar fasciitis (fasciosis) treatment outcome study: plantar fascia thickness measured by ultrasound and correlated with patient self-reported improvement. (21398108)
2011
18
Necrotizing fasciitis following BCG vaccination. (21478557)
2011
19
Right hip necrotizing fasciitis. (21107236)
2011
20
Nodular fasciitis of the orbit: a case report and brief review of the literature. (22611507)
2011
21
Nodular fasciitis of the chest: case report of a rare presentation. (21503721)
2011
22
Cervical necrotising fasciitis with descending necrotising mediastinitis. (21493637)
2011
23
Rearfoot alignment and medial longitudinal arch configurations of runners with symptoms and histories of plantar fasciitis. (21808870)
2011
24
Management of necrotizing fasciitis infections. (21323228)
2011
25
Clinical and microbiological spectrum of necrotizing fasciitis in surgical patients at a Philippine university medical centre. (20497883)
2010
26
Cervical necrotizing fasciitis originating with a periapical infection. (20592406)
2010
27
Subcutaneous emphysema, muscular necrosis, and necrotizing fasciitis: an unusual presentation of perforated sigmoid diverticulitis. (20224508)
2010
28
Necrotizing fasciitis of the thigh should raise suspicion of a rectal cancer. (20708997)
2010
29
Pyoderma gangrenosum masquerading as necrotizing fasciitis. (19563941)
2009
30
Sonographic findings of necrotizing fasciitis in the breast. (18454477)
2008
31
Necrotizing fasciitis with no mortality or limb loss. (18807667)
2008
32
Aggressive management of necrotizing fasciitis through a multidisciplinary approach using minimal surgical procedures: a case report. (19825711)
2008
33
Incidence and clinical characteristics of methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a large urban hospital. (18005776)
2007
34
Case of fasciitis panniculitis syndrome. (17204110)
2007
35
Fasciitislike papillary Carcinoma of the thyroid gland. (16124181)
2005
36
Ultrasonographic evaluation at 6-month follow-up of plantar fasciitis after extracorporeal shock wave therapy. (14530990)
2005
37
Effectiveness of low-Dye taping for the short-term management of plantar fasciitis. (16291843)
2005
38
Circulating soluble CD40 ligand in patients with eosinophilic fasciitis. (12525399)
2003
39
Clinical inquiries. What is the best treatment for plantar fasciitis? (12967545)
2003
40
A prospective trial of night splinting in the treatment of recalcitrant plantar fasciitis: the Ankle Dorsiflexion Dynasplint. (12452346)
2002
41
Ultrasound-guided extracorporeal shock wave therapy for plantar fasciitis: a randomized controlled trial. (12234230)
2002
42
Analysis of leukemia inhibitory factor, type 1 and type 2 cytokine production in patients with eosinophilic fasciitis. (11196547)
2001
43
Flesh-eating disease: A note on necrotizing fasciitis. (18159329)
2001
44
The instep plantar fasciotomy for chronic plantar fasciitis. A retrospective review. (10697969)
2000
45
Comparison of custom and prefabricated orthoses in the initial treatment of proximal plantar fasciitis. (10229276)
1999
46
Possible association between eosinophilic fasciitis and subcutaneous heparin use. (9489839)
1998
47
Elevated serum eosinophilic cationic protein (ECP) and expression of pemphigus-like antibodies in a case of eosinophilic fasciitis. (9196881)
1997
48
Proliferative fasciitis. Report of a case with histopathologic and immunohistochemical studies. (9261476)
1997
49
Surgical implications of necrotizing fasciitis in children with chickenpox. (8863250)
1996
50
Familial eosinophilic fasciitis and breast cancer. (8162468)
1994

Genetic Variations for Fasciitis

Expression for genes affiliated with Fasciitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Fasciitis

Search GEO for disease gene expression data for Fasciitis.

Pathways for genes affiliated with Fasciitis

Sources:
38NCBI BioSystems Database
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Pathways related to Fasciitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2MYOG, MED12, CTNNB1

Compounds for genes affiliated with Fasciitis

Sources:
45Novoseek, 11DrugBank, 24HMDB, 29IUPHAR, 50PharmGKB, 60Tocris Bioscience
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Compounds related to Fasciitis according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1policosanol4510.7GPT, PIK3C2A
2alpha-hydroxybutyrate4510.6GPT, PIK3C2A
3orcein4510.6ACTC1, DES
4unicap4510.6IL5, IGHE
5omalizumab45 1111.6IGHE, IL5
6oxatomide4510.6IGHE, IL5
7ovomucoid4510.6IGHE
8methylcellulose4510.6IL5, AHR, CTNNB1
9s 1004510.6ACTC1, DES
10d-galactosamine4510.6GPT, DES
11glycogen45 2411.6ACTC1, PIK3C2A, CTNNB1
12gemfibrozil45 29 1112.6GPT, PIK3C2A, DES
13bezafibrate45 29 1112.6GPT, PIK3C2A, DES
14beclomethasone dipropionate4510.6IGHE, IL5
15estrogen4510.5MYOG
16imatinib45 50 1112.5ACTC1, IL5, DES, CTNNB1
17p-0074510.5GPT, PIK3C2A
18fenofibrate45 50 1112.5DES, PIK3C2A, GPT
19ivig4510.5IGHE, PIK3C2A, GPT, IL5
20prednisolone45 29 1112.5IL5, PIK3C2A, IGHE, GPT
21toluene diisocyanate4510.4IGHE, IL5
22glycerol45 11 2412.4AHR, IGHE, PIK3C2A, CTNNB1
23methotrexate45 50 1112.4PIK3C2A, GPT, IL5, IGHE
24vitamin d4510.4AHR, GPT, IL5, CTNNB1, IGHE
25thyroxine45 2411.4GPT, PIK3C2A, IGHE, AHR, IL5
26sodium cromoglycate4510.4IGHE, IL5
27paraffin4510.4MYOG, ACTC1, IL5, CTNNB1, CD46, DES
28glutamine4510.3GPT, IL5, AHR, IGHE, CTNNB1
29pge14510.3IGHE, GPT, PIK3C2A
30fatty acid4510.3DES, CTNNB1, PIK3C2A, MYOG, FABP6
31cyclosporin a45 29 6012.3CD46, IL5, ACTC1, GPT, PIK3C2A, IGHE
32adenylate4510.3DES, IL5, IGHE, MYOG, AHR, GPT
33n acetylcysteine4510.3GPT, IGHE, AHR, CTNNB1
34cetirizine45 29 11 2413.3IGHE, IL5
35phenobarbital45 29 1112.2CTNNB1, AHR, GPT
36dexamethasone45 50 29 1113.2IGHE, CTNNB1, AHR, IL5, NPHS1, ACTC1
37aspartate4510.2AHR, GPT, PIK3C2A, CTNNB1, IGHE
38steroid4510.2CTNNB1, PIK3C2A, NPHS1, AHR, MYOG, DES
39ascorbic acid45 2411.2PIK3C2A, IGHE, AHR, MYOG
40creatinine4510.2PIK3C2A, DES, IGHE, MYOG, NPHS1, ACTC1
41glycocholate4510.2GPT, FABP6
42glutamate4510.2IGHE, PIK3C2A, IL5, CTNNB1, GPT, AHR
43alanine4510.2CD46, IGHE, PIK3C2A, CTNNB1, GPT, AHR
44retinoic acid45 2411.1ACTC1, MYOG, AHR, IGHE, NPHS1, DES
45testosterone45 60 11 2413.1DES, IGHE, MYOG, AHR, PIK3C2A, IL5
46arginine4510.1IGHE, IL5, AHR, DES, PIK3C2A, GPT
47tyrosine4510.1IL5, MYOG, DES, PIK3C2A, CTNNB1, CD46
48vegf4510.0MYOG, ACTC1, IL5, IGHE, PIK3C2A, CTNNB1
49progesterone45 60 29 11 2414.0CTNNB1, PIK3C2A, DES, CD46, ACTC1
50glucose459.6DES, MYOG, PIK3C2A, NPHS1, GPT, ACTC1

GO Terms for genes affiliated with Fasciitis

Sources:
16Gene Ontology
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Cellular components related to Fasciitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1fascia adherensGO:00591610.3DES, CTNNB1
2protein-DNA complexGO:03299310.0MYOG, CTNNB1

Products for genes affiliated with Fasciitis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Fasciitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet