MCID: FSC004
MIFTS: 45

Fasciitis malady

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Summaries for Fasciitis

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Sources:
65Wikipedia, 33MalaCards
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Wikipedia:65 In medicine, fasciitis /?f more...

MalaCards: Fasciitis is related to necrotizing fasciitis and eosinophilic fasciitis. An important gene associated with Fasciitis is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways are Hypertrophic cardiomyopathy (HCM) and Striated Muscle Contraction. The compounds nash and clarithromycin have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and thyroid, and related mouse phenotype muscle.

Aliases & Classifications for Fasciitis

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8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 35MeSH, 58SNOMED-CT, 40NCIt, 27ICD9CM
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Aliases & Descriptions:

fasciitis 8 10 45 62


External Ids:

Disease Ontology8 DOID:9598
MeSH35 D005208
SNOMED-CT58 36948007, 203123000
NCIt40 C50559
ICD9CM27 729.4

Related Diseases for Fasciitis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Fasciitis:



Diseases related to fasciitis

Symptoms for Fasciitis

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Drugs & Therapeutics for Fasciitis

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Fasciitis

Search NIH Clinical Center for Fasciitis

Genetic Tests for Fasciitis

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Anatomical Context for Fasciitis

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33MalaCards
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MalaCards organs/tissues related to Fasciitis:

33
Breast, Bone, Thyroid, Colon, Bone marrow, Skin, T cells, Kidney, Liver, Tonsil, Small intestine, Monocytes, Myeloid, Testes, Lung, Spinal cord, Smooth muscle, Lymph node, Prostate, Heart, Pancreas

Animal Models for Fasciitis or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Fasciitis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.2ACTC1, AHR, DES, SPEG

Publications for Fasciitis

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Sources:
52PubMed
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Articles related to Fasciitis:

(show top 50)    (show all 1524)
idTitleAuthorsYear
1
Comment on Sharma: platelet-rich-plasma injections for chronic planter fasciitis. (24384942)
2014
2
Fulminant necrotizing fasciitis caused by Serratia marcescens in an immunosuppressed host. (22640271)
2014
3
Subcalcaneal bursitis with plantar fasciitis treated by arthroscopy. (23875139)
2013
4
Temporizing surgical management improves outcome in patients with Vibrio necrotizing fasciitis complicated with septic shock on admission. (24138809)
2013
5
A rare case of necrotising fasciitis after spinal anaesthesia. (23983303)
2013
6
Nodular fasciitis over the anterior wall of the maxillary sinus: a case report and review of the literature. (23217546)
2013
7
Intraarticular nodular fasciitis of the hip. (23329303)
2013
8
Necrotizing fasciitis involving the chest and abdominal wall caused by Raoultella planticola. (22423899)
2012
9
Nodular fasciitis with cortical erosion of the hand. (22379562)
2012
10
Necrotizing fasciitis caused by a primary appendicocutaneous fistula. (22318638)
2012
11
Cervicofacial necrotizing fasciitis following periodontal abscess. (22782044)
2012
12
Group a streptococcus necrotizing fasciitis of the eyelid: a case report of good outcome with medical management. (21415799)
2012
13
Klebsiella pneumoniae cervical necrotizing fasciitis originating as an abscess. (22809880)
2012
14
Life-threatening necrotizing fasciitis due to 'bath salts' injection. (22229605)
2012
15
Diagnosis and management of necrotizing fasciitis. (21410101)
2011
16
Unusual case of necrotizing fasciitis caused by Vibrio cholerae O137. (21159937)
2011
17
Necrotizing fasciitis of the head and neck. (20848400)
2010
18
Adapting a Vacuum Assisted Closure dressing to challenging wounds: negative pressure treatment for perineal necrotizing fasciitis with rectal prolapse in a newborn affected by acute myeloid leukaemia. (20406723)
2010
19
Molecular pathogenesis of necrotizing fasciitis. (19737105)
2010
20
Necrotizing fasciitis due to Pseudomonas aeruginosa in immuno-compromised children. (20486189)
2010
21
Bilateral Baxter's neuropathy secondary to plantar fasciitis. (20357723)
2010
22
Necrotizing fasciitis in southeast Taiwan: clinical features, microbiology, and prognosis. (18922719)
2009
23
Operative treatment of plantar fasciitis preserving the function of the plantar fascia: technique tip. (19796599)
2009
24
The epidemiology of necrotizing fasciitis including factors associated with death and amputation. (19351432)
2009
25
Necrotizing fasciitis. Case report. (19093634)
2008
26
Physical burden of symptoms in patients with localized scleroderma and eosinophilic fasciitis. (18936410)
2008
27
Randomized multicenter trial on the effect of radiotherapy for plantar Fasciitis (painful heel spur) using very low doses--a study protocol. (18801159)
2008
28
Community-acquired methicillin-resistant Staphylococcus aureus emerging as an important cause of necrotizing fasciitis. (18399783)
2008
29
The effect of topical wheatgrass cream on chronic plantar fasciitis: a randomized, double-blind, placebo-controlled trial. (16473748)
2006
30
The safety and efficacy of high energy extracorporeal shock wave therapy in active, moderately active, and sedentary patients with chronic plantar fasciitis. (16119283)
2005
31
Rapid involution of proliferative fasciitis. (14985873)
2004
32
Streptococcal necrotizing fasciitis with toxic shock syndrome following cervical adenitis. (15302155)
2004
33
Shock wave therapy for treatment of plantar fasciitis. (12517214)
2003
34
A prospective trial of night splinting in the treatment of recalcitrant plantar fasciitis: the Ankle Dorsiflexion Dynasplint. (12452346)
2002
35
Monocytic fasciitis: a newly recognized clinical feature of tumor necrosis factor receptor dysfunction. (12209524)
2002
36
Analysis of leukemia inhibitory factor, type 1 and type 2 cytokine production in patients with eosinophilic fasciitis. (11196547)
2001
37
Eosinophilic fasciitis presenting as pitting edema of the extremities. (11566463)
2001
38
Intravascular fasciitis of the forearm vein: a case report with immunohistochemical characterization. (10355974)
1999
39
Iontophoresis of 0.4% dexamethasone for plantar fasciitis. (9490178)
1998
40
Eosinophilic fasciitis with myelodysplasia responsive to treatment with cyclosporin. (9068764)
1997
41
Eosinophilia-myalgia syndrome, toxic-oil syndrome, and diffuse fasciitis with eosinophilia. (8579979)
1995
42
Association of eosinophilic fasciitis, multiple morphea and antiphospholipid antibody. (7949491)
1994
43
Magnetic resonance imaging of plantar fasciitis and other causes of heel pain. (7584243)
1994
44
Ultrasound diagnosis of plantar fasciitis. (8253440)
1993
45
Eosinophilic fasciitis in children frequently progresses to scleroderma-like cutaneous fibrosis. (8441144)
1993
46
Conjunctival chemosis in eosinophilic fasciitis. (2606225)
1989
47
Frequency, levels, and significance of blood eosinophilia in systemic sclerosis, localized scleroderma, and eosinophilic fasciitis. (3668010)
1987
48
Cutaneous sclerosis in eosinophilic fasciitis. (510651)
1979
49
Eosinophilic fasciitis: a scleroderma-like illness. (576278)
1977
50
Treatment of plantar fasciitis and calcaneal spurs with the UC-BL shoe insert. (4416727)
1974

Variations for Fasciitis

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Expression for genes affiliated with Fasciitis

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Fasciitis

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Pathways for genes affiliated with Fasciitis

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50PathCards, 30KEGG, 38NCBI BioSystems Database, 55Reactome
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Pathways related to Fasciitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Arrhythmogenic right ventricular cardiomyopathy38
9.5ACTC1, DES
2
Show member pathways
9.5ACTC1, DES

Compounds for genes affiliated with Fasciitis

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Sources:
45Novoseek, 11DrugBank, 29IUPHAR, 51PharmGKB, 61Tocris Bioscience, 24HMDB, 3BitterDB
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Compounds related to Fasciitis according to GeneCards/GeneDecks:

(show all 47)
idCompoundScoreTop Affiliating Genes
1nash4510.0ACTC1, GPT
2clarithromycin45 1110.9GPT, IL5
3orcein459.9ACTC1, DES
4s 100459.9ACTC1, DES
5reticulin459.9ACTC1, DES
6mucicarmine459.9ACTC1, DES
7ivig459.9GPT, IL5
8b 723459.9ACTC1, DES
9percoll459.8IL5, DES
10hematoxylin459.8DES, ACTC1
11d-galactosamine459.8DES, GPT
12procollagen459.7ACTC1, DES
13gemfibrozil29 45 1111.7DES, GPT
14bezafibrate45 29 1111.7DES, GPT
15fenofibrate45 51 1111.7GPT, DES
16ccl445 2910.6GPT, DES
17methylcellulose459.6IL5, AHR
18asparagine459.6GPT, CD46
19flutamide45 61 1111.5GPT, AHR
20imatinib45 51 1111.5IL5, ACTC1, DES
21biotin45 24 1111.5DES, ACTC1
22rifampicin45 29 6111.5AHR, GPT
23azathioprine45 3 51 1112.4GPT, DES
24glycogen45 2410.3ACTC1, GPT, DES
25phenobarbital45 29 51 1112.3GPT, AHR
26iron45 2410.3DES, GPT, ACTC1
27creatinine459.3ACTC1, GPT, DES
28prednisolone45 29 1111.2IL5, GPT
29progestin459.2AHR, DES
30p002459.2GPT, DES
31progesterone45 29 61 24 1113.2CD46, ACTC1, DES
32thyroxine45 2410.1AHR, GPT, IL5
33atorvastatin45 51 29 24 1113.1GPT, AHR
34vitamin d459.1AHR, GPT, IL5
35cyclosporin a45 29 6111.1GPT, ACTC1, IL5, CD46
36glutamine459.1IL5, GPT, AHR
37cycloheximide459.0CD46, IL5, AHR
38paraffin459.0CD46, IL5, ACTC1, DES
39steroid458.8ACTC1, AHR, DES
40tyrosine458.8DES, ACTC1, IL5, CD46
41dexamethasone45 51 29 1111.8AHR, ACTC1, IL5, CD46
42testosterone45 61 24 1111.7IL5, ACTC1, AHR, DES
43vegf458.7IL5, ACTC1, AHR, DES
44retinoic acid45 249.6IL5, ACTC1, AHR, DES
45adenylate458.5IL5, GPT, AHR, DES
46arginine458.5DES, AHR, GPT, IL5
47serine458.4DES, AHR, IL5, CD46

GO Terms for genes affiliated with Fasciitis

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16Gene Ontology
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Biological processes related to Fasciitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:0300499.5ACTC1, DES

Products for genes affiliated with Fasciitis

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  • Antibodies
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  • Antibodies

Sources for Fasciitis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet