MCID: FSC004
MIFTS: 50

Fasciitis malady

Summaries for Fasciitis

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63Wikipedia, 32MalaCards
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Wikipedia:63 In medicine, fasciitis /ˌfæʃiˈaɪtɪs/ refers to an inflammation of the fascia, which is the... more...

MalaCards: Fasciitis is related to necrotizing fasciitis and plantar fasciitis. An important gene associated with Fasciitis is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways is Regulation of Wnt-mediated beta catenin signaling and target gene transcription. The compounds policosanol and alpha-hydroxybutyrate have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and thyroid, and related mouse phenotypes are cardiovascular system and mortality/aging.

Aliases & Classifications for Fasciitis

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 27ICD9CM, 39NCIt, 34MeSH, 56SNOMED-CT
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Aliases & Descriptions:

fasciitis 8 10 44 60


External Ids:

Disease Ontology8 DOID:9598
ICD9CM27 729.4
SNOMED-CT56 203123000, 36948007
NCIt39 C50559
MeSH34 D005208

Related Diseases for Fasciitis

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Fasciitis:



Diseases related to fasciitis

Clinical Features for Fasciitis

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Drugs & Therapeutics for Fasciitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Fasciitis

Drug clinical trials:

Search ClinicalTrials for Fasciitis

Search NIH Clinical Center for Fasciitis

Search CenterWatch for Fasciitis

Genetic Tests for Fasciitis

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Anatomical Context for Fasciitis

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32MalaCards
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MalaCards organs/tissues related to Fasciitis:

32
Breast, Bone, Thyroid, Colon, Skin, Bone marrow, T cells, Kidney, Liver, Tonsil, Testes, Spinal cord, Small intestine, Smooth muscle, Monocytes, Myeloid, Lung, Lymph node, Pancreas, Prostate, Heart

Animal Models for Fasciitis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Fasciitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053859.7CTNNB1, MED12, DES, TRPC4AP, AHR, ACTC1
2MP:00107689.1SPEG, CCNF, NPHS1, CTNNB1, PIK3C2A, MED12
3MP:00053769.1CTNNB1, FABP6, NPHS1, CARD9, PIK3C2A, DES

Publications for Fasciitis

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50PubMed
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Articles related to Fasciitis:

(show top 50)    (show all 1540)
idTitleAuthorsYear
1
Diagnosis and classification of eosinophilic fasciitis. (24424187)
2014
2
Nodular fasciitis: an uncommon disease with common medical management challenges at a remote Naval Hospital. (24005559)
2013
3
Necrotizing fasciitis of the lower extremity caused by Shewanella algae. (23451727)
2013
4
Variable Ki67 proliferative index in 65 cases of nodular fasciitis, compared with fibrosarcoma and fibromatosis. (23531088)
2013
5
Necrotising fasciitis of odontogenic origin. (23821623)
2013
6
Necrotising fasciitis: a series of seven cases. (23547524)
2013
7
Group A streptococcal necrotizing fasciitis in the emergency department. (23937806)
2013
8
Cervical nodular fasciitis in a 17-month-old child. (23814003)
2013
9
Cervicofacial necrotizing fasciitis following periodontal abscess. (22782044)
2012
10
Klebsiella pneumoniae cervical necrotizing fasciitis originating as an abscess. (22809880)
2012
11
Necrotizing fasciitis of the lower limb following rat bites. (22692840)
2012
12
Plantar fasciitis. (23131221)
2012
13
Necrotizing fasciitis secondary to the insertion of a cardiac pacemaker. (23257970)
2012
14
Extradural nodular fasciitis arising in the spinal canal. (21629160)
2012
15
Necrotizing upper limb fasciitis in a newborn: an uncommon life-threatening event. (22080297)
2012
16
Diagnosis and management of necrotizing fasciitis. (21410101)
2011
17
Necrotizing fasciitis: early sonographic diagnosis. (21480291)
2011
18
Case report: nodular fasciitis of the parotid region. (21888742)
2011
19
Herpes simplex virus type 2 mimicking necrotizing fasciitis. (22007058)
2011
20
Necrotizing fasciitis in the setting of marine injury. (21093192)
2011
21
Necrotizing fasciitis causing severe myocardial dysfunction with ST-segment elevation in a young man. (20159418)
2010
22
Modern concepts of the diagnosis and treatment of necrotizing fasciitis. (19081698)
2010
23
A difficult case of necrotizing fasciitis caused by Acinetobacter baumannii. (21134952)
2010
24
Plantar fasciitis: current diagnostic modalities and treatments. (20691370)
2010
25
Necrotizing fasciitis and myositis caused by streptococcal flesh-eating bacteria. (21085016)
2010
26
Prevalence of necrotizing fasciitis during Ramadan and Hajj 1427-H. (20364760)
2009
27
A devastating case of heroin-associated necrotizing fasciitis of the upper limb with bone exposure. A useful method of treatment. (19064341)
2009
28
Craniocervical necrotizing fasciitis with and without thoracic extension: management strategies and outcome. (19027508)
2009
29
Early diagnosis of necrotizing fasciitis with soft tissue ultrasound. (19732035)
2009
30
Case cluster of necrotizing fasciitis and cellulitis associated with vein sclerotherapy. (18258105)
2008
31
Is early diagnosis of necrotizing fasciitis important? (18959691)
2008
32
Necrotizing fasciitis of the shoulder following routine rotator cuff repair. A case report. (18451406)
2008
33
Necrotizing fasciitis and gangrene associated with topical herbs in an infant. (17901041)
2007
34
Heel pain-plantar fasciitis and Achilles enthesopathy. (15062587)
2004
35
Cytokine abnormalities in a patient with eosinophilic fasciitis. (12722970)
2003
36
Symptom duration of plantar fasciitis and the effectiveness of Orthotripsy. (14733347)
2003
37
Treatment of plantar fasciitis. (11272297)
2001
38
Post-varicella epiglottitis and necrotizing fasciitis. (10617750)
2000
39
Extracorporeal shock wave application for chronic plantar fasciitis associated with heel spurs: prediction of outcome by magnetic resonance imaging. (11036844)
2000
40
An inexpensive "orthosis" for plantar fasciitis. (9397072)
1997
41
Necrotizing fasciitis of the head and neck: Report of three cases. (17338016)
1997
42
Plantar fasciitis, posterior night splints and activity during recovery. (8623712)
1996
43
Systemic lupus erythematosus and eosinophilic fasciitis: an unusual association. (8549105)
1995
44
Eosinophilic fasciitis after allogeneic bone marrow transplantation. (2359082)
1990
45
Eosinophilic fasciitis in children. (2690343)
1989
46
Morphea developing in patients previously affected with eosinophilic fasciitis. Report of two cases. (3238279)
1988
47
Predicting plantar fasciitis in runners. (2881184)
1987
48
Pathology of eosinophilic fasciitis and its relation to polymyositis. (3690437)
1987
49
Childhood eosinophilic fasciitis--progression to linear scleroderma. (3820208)
1986
50
Eosinophilic fasciitis. (7436214)
1980

Genetic Variations for Fasciitis

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Expression for genes affiliated with Fasciitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Fasciitis

Search GEO for disease gene expression data for Fasciitis.

Pathways for genes affiliated with Fasciitis

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37NCBI BioSystems Database
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Pathways related to Fasciitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2MYOG, MED12, CTNNB1

Compounds for genes affiliated with Fasciitis

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Sources:
44Novoseek, 11DrugBank, 24HMDB, 28IUPHAR, 49PharmGKB, 59Tocris Bioscience
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Compounds related to Fasciitis according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1policosanol4410.7GPT, PIK3C2A
2alpha-hydroxybutyrate4410.6GPT, PIK3C2A
3orcein4410.6DES, ACTC1
4omalizumab44 1111.6IL5, IGHE
5unicap4410.6IL5, IGHE
6oxatomide4410.6IGHE, IL5
7ovomucoid4410.6IGHE
8methylcellulose4410.6IL5, AHR, CTNNB1
9d-galactosamine4410.6GPT, DES
10glycogen44 2411.6ACTC1, PIK3C2A, CTNNB1
11s 1004410.6DES, ACTC1
12gemfibrozil44 28 1112.6PIK3C2A, DES, GPT
13bezafibrate44 28 1112.6PIK3C2A, DES, GPT
14beclomethasone dipropionate4410.6IL5, IGHE
15estrogen4410.5MYOG
16imatinib44 49 1112.5CTNNB1, DES, IL5, ACTC1
17p-0074410.5PIK3C2A, GPT
18fenofibrate44 49 1112.5PIK3C2A, DES, GPT
19ivig4410.5PIK3C2A, IGHE, IL5, GPT
20prednisolone44 28 1112.5GPT, IL5, IGHE, PIK3C2A
21sodium cromoglycate4410.4IGHE, IL5
22glycerol44 11 2412.4CTNNB1, PIK3C2A, IGHE, AHR
23methotrexate44 49 1112.4PIK3C2A, IGHE, IL5, GPT
24vitamin d4410.4CTNNB1, IGHE, AHR, IL5, GPT
25thyroxine44 2411.4PIK3C2A, IGHE, AHR, IL5, GPT
26toluene diisocyanate4410.4IGHE, IL5
27paraffin4410.4CTNNB1, DES, MYOG, CD46, IL5, ACTC1
28glutamine4410.3CTNNB1, IGHE, AHR, IL5, GPT
29pge14410.3GPT, IGHE, PIK3C2A
30fatty acid4410.3FABP6, CTNNB1, PIK3C2A, DES, MYOG
31cyclosporin a44 28 5912.3PIK3C2A, IGHE, CD46, IL5, GPT, ACTC1
32adenylate4410.3DES, IGHE, MYOG, AHR, IL5, GPT
33n acetylcysteine4410.3CTNNB1, IGHE, AHR, GPT
34cetirizine44 28 11 2413.3IL5, IGHE
35phenobarbital44 28 1112.2GPT, AHR, CTNNB1
36dexamethasone44 49 28 1113.2NPHS1, CTNNB1, IGHE, CD46, AHR, IL5
37aspartate4410.2CTNNB1, PIK3C2A, IGHE, AHR, GPT
38steroid4410.2NPHS1, CTNNB1, PIK3C2A, DES, MYOG, AHR
39ascorbic acid44 2411.2PIK3C2A, IGHE, MYOG, AHR
40creatinine4410.2NPHS1, PIK3C2A, DES, IGHE, MYOG, GPT
41glycocholate4410.2GPT, FABP6
42glutamate4410.2CTNNB1, PIK3C2A, IGHE, AHR, IL5, GPT
43alanine4410.2CTNNB1, PIK3C2A, IGHE, CD46, AHR, GPT
44retinoic acid44 2411.1NPHS1, CTNNB1, DES, IGHE, MYOG, AHR
45testosterone44 59 11 2413.1CTNNB1, PIK3C2A, DES, IGHE, MYOG, AHR
46arginine4410.1NPHS1, CTNNB1, PIK3C2A, DES, IGHE, AHR
47tyrosine4410.1NPHS1, CTNNB1, PIK3C2A, DES, MYOG, CD46
48vegf4410.0ACTC1, NPHS1, CTNNB1, PIK3C2A, DES, IGHE
49progesterone44 59 28 11 2414.0CTNNB1, PIK3C2A, DES, CD46, ACTC1
50glucose449.6NPHS1, PIK3C2A, DES, MYOG, GPT, ACTC1

GO Terms for genes affiliated with Fasciitis

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16Gene Ontology
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Cellular components related to Fasciitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1fascia adherensGO:00591610.3DES, CTNNB1
2protein-DNA complexGO:03299310.0MYOG, CTNNB1

Products for genes affiliated with Fasciitis

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  • Antibodies
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  • Lysates
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Sources for Fasciitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet