MCID: FSC004
MIFTS: 45

Fasciitis malady

Summaries for Fasciitis

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 In medicine, fasciitis /?f more...

MalaCards: Fasciitis is related to necrotizing fasciitis and eosinophilic fasciitis. An important gene associated with Fasciitis is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways are Hypertrophic cardiomyopathy (HCM) and Striated Muscle Contraction. The compounds nash and clarithromycin have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and thyroid, and related mouse phenotype muscle.

Aliases & Classifications for Fasciitis

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9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 36MeSH, 59SNOMED-CT, 41NCIt, 28ICD9CM
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Aliases & Descriptions:

fasciitis 9 11 46 63


External Ids:

Disease Ontology9 DOID:9598
MeSH36 D005208
SNOMED-CT59 36948007, 203123000
NCIt41 C50559
ICD9CM28 729.4

Related Diseases for Fasciitis

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Fasciitis:



Diseases related to fasciitis

Symptoms for Fasciitis

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Drugs & Therapeutics for Fasciitis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Fasciitis

Drug clinical trials:

Search ClinicalTrials for Fasciitis

Search NIH Clinical Center for Fasciitis

Search CenterWatch for Fasciitis

Genetic Tests for Fasciitis

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Anatomical Context for Fasciitis

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Sources:
34MalaCards
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MalaCards organs/tissues related to Fasciitis:

34
Breast, Bone, Thyroid, Colon, Bone marrow, Skin, T cells, Kidney, Liver, Tonsil, Small intestine, Monocytes, Myeloid, Testes, Lung, Spinal cord, Smooth muscle, Lymph node, Prostate, Heart, Pancreas

Animal Models for Fasciitis or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Fasciitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.2ACTC1, AHR, DES, SPEG

Publications for Fasciitis

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Sources:
53PubMed
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Articles related to Fasciitis:

(show top 50)    (show all 1524)
idTitleAuthorsYear
1
Comment on Sharma: platelet-rich-plasma injections for chronic planter fasciitis. (24384942)
2014
2
Fulminant necrotizing fasciitis caused by Serratia marcescens in an immunosuppressed host. (22640271)
2014
3
Subcalcaneal bursitis with plantar fasciitis treated by arthroscopy. (23875139)
2013
4
Temporizing surgical management improves outcome in patients with Vibrio necrotizing fasciitis complicated with septic shock on admission. (24138809)
2013
5
A rare case of necrotising fasciitis after spinal anaesthesia. (23983303)
2013
6
Nodular fasciitis over the anterior wall of the maxillary sinus: a case report and review of the literature. (23217546)
2013
7
Intraarticular nodular fasciitis of the hip. (23329303)
2013
8
Necrotizing fasciitis involving the chest and abdominal wall caused by Raoultella planticola. (22423899)
2012
9
Nodular fasciitis with cortical erosion of the hand. (22379562)
2012
10
Necrotizing fasciitis caused by a primary appendicocutaneous fistula. (22318638)
2012
11
Cervicofacial necrotizing fasciitis following periodontal abscess. (22782044)
2012
12
Group a streptococcus necrotizing fasciitis of the eyelid: a case report of good outcome with medical management. (21415799)
2012
13
Klebsiella pneumoniae cervical necrotizing fasciitis originating as an abscess. (22809880)
2012
14
Life-threatening necrotizing fasciitis due to 'bath salts' injection. (22229605)
2012
15
Diagnosis and management of necrotizing fasciitis. (21410101)
2011
16
Unusual case of necrotizing fasciitis caused by Vibrio cholerae O137. (21159937)
2011
17
Necrotizing fasciitis of the head and neck. (20848400)
2010
18
Adapting a Vacuum Assisted Closure dressing to challenging wounds: negative pressure treatment for perineal necrotizing fasciitis with rectal prolapse in a newborn affected by acute myeloid leukaemia. (20406723)
2010
19
Molecular pathogenesis of necrotizing fasciitis. (19737105)
2010
20
Necrotizing fasciitis due to Pseudomonas aeruginosa in immuno-compromised children. (20486189)
2010
21
Bilateral Baxter's neuropathy secondary to plantar fasciitis. (20357723)
2010
22
Necrotizing fasciitis in southeast Taiwan: clinical features, microbiology, and prognosis. (18922719)
2009
23
Operative treatment of plantar fasciitis preserving the function of the plantar fascia: technique tip. (19796599)
2009
24
The epidemiology of necrotizing fasciitis including factors associated with death and amputation. (19351432)
2009
25
Necrotizing fasciitis. Case report. (19093634)
2008
26
Physical burden of symptoms in patients with localized scleroderma and eosinophilic fasciitis. (18936410)
2008
27
Randomized multicenter trial on the effect of radiotherapy for plantar Fasciitis (painful heel spur) using very low doses--a study protocol. (18801159)
2008
28
Community-acquired methicillin-resistant Staphylococcus aureus emerging as an important cause of necrotizing fasciitis. (18399783)
2008
29
The effect of topical wheatgrass cream on chronic plantar fasciitis: a randomized, double-blind, placebo-controlled trial. (16473748)
2006
30
The safety and efficacy of high energy extracorporeal shock wave therapy in active, moderately active, and sedentary patients with chronic plantar fasciitis. (16119283)
2005
31
Rapid involution of proliferative fasciitis. (14985873)
2004
32
Streptococcal necrotizing fasciitis with toxic shock syndrome following cervical adenitis. (15302155)
2004
33
Shock wave therapy for treatment of plantar fasciitis. (12517214)
2003
34
A prospective trial of night splinting in the treatment of recalcitrant plantar fasciitis: the Ankle Dorsiflexion Dynasplint. (12452346)
2002
35
Monocytic fasciitis: a newly recognized clinical feature of tumor necrosis factor receptor dysfunction. (12209524)
2002
36
Analysis of leukemia inhibitory factor, type 1 and type 2 cytokine production in patients with eosinophilic fasciitis. (11196547)
2001
37
Eosinophilic fasciitis presenting as pitting edema of the extremities. (11566463)
2001
38
Intravascular fasciitis of the forearm vein: a case report with immunohistochemical characterization. (10355974)
1999
39
Iontophoresis of 0.4% dexamethasone for plantar fasciitis. (9490178)
1998
40
Eosinophilic fasciitis with myelodysplasia responsive to treatment with cyclosporin. (9068764)
1997
41
Eosinophilia-myalgia syndrome, toxic-oil syndrome, and diffuse fasciitis with eosinophilia. (8579979)
1995
42
Association of eosinophilic fasciitis, multiple morphea and antiphospholipid antibody. (7949491)
1994
43
Magnetic resonance imaging of plantar fasciitis and other causes of heel pain. (7584243)
1994
44
Ultrasound diagnosis of plantar fasciitis. (8253440)
1993
45
Eosinophilic fasciitis in children frequently progresses to scleroderma-like cutaneous fibrosis. (8441144)
1993
46
Conjunctival chemosis in eosinophilic fasciitis. (2606225)
1989
47
Frequency, levels, and significance of blood eosinophilia in systemic sclerosis, localized scleroderma, and eosinophilic fasciitis. (3668010)
1987
48
Cutaneous sclerosis in eosinophilic fasciitis. (510651)
1979
49
Eosinophilic fasciitis: a scleroderma-like illness. (576278)
1977
50
Treatment of plantar fasciitis and calcaneal spurs with the UC-BL shoe insert. (4416727)
1974

Variations for Fasciitis

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Expression for genes affiliated with Fasciitis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Fasciitis

Search GEO for disease gene expression data for Fasciitis.

Pathways for genes affiliated with Fasciitis

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51PathCards, 31KEGG, 39NCBI BioSystems Database, 56Reactome
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Pathways related to Fasciitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Arrhythmogenic right ventricular cardiomyopathy39
9.5ACTC1, DES
2
Show member pathways
9.5ACTC1, DES

Compounds for genes affiliated with Fasciitis

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Sources:
46Novoseek, 12DrugBank, 30IUPHAR, 52PharmGKB, 62Tocris Bioscience, 25HMDB, 3BitterDB
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Compounds related to Fasciitis according to GeneCards/GeneDecks:

(show all 47)
idCompoundScoreTop Affiliating Genes
1nash4610.0ACTC1, GPT
2clarithromycin46 1210.9GPT, IL5
3orcein469.9ACTC1, DES
4s 100469.9ACTC1, DES
5reticulin469.9ACTC1, DES
6mucicarmine469.9ACTC1, DES
7ivig469.9GPT, IL5
8b 723469.9ACTC1, DES
9percoll469.8IL5, DES
10hematoxylin469.8DES, ACTC1
11d-galactosamine469.8DES, GPT
12procollagen469.7ACTC1, DES
13gemfibrozil30 46 1211.7DES, GPT
14bezafibrate46 30 1211.7DES, GPT
15fenofibrate46 52 1211.7GPT, DES
16ccl446 3010.6GPT, DES
17methylcellulose469.6IL5, AHR
18asparagine469.6GPT, CD46
19flutamide46 62 1211.5GPT, AHR
20imatinib46 52 1211.5IL5, ACTC1, DES
21biotin46 25 1211.5DES, ACTC1
22rifampicin46 30 6211.5AHR, GPT
23azathioprine46 3 52 1212.4GPT, DES
24glycogen46 2510.3ACTC1, GPT, DES
25phenobarbital46 30 52 1212.3GPT, AHR
26iron46 2510.3DES, GPT, ACTC1
27creatinine469.3ACTC1, GPT, DES
28prednisolone46 30 1211.2IL5, GPT
29progestin469.2AHR, DES
30p002469.2GPT, DES
31progesterone46 30 62 25 1213.2CD46, ACTC1, DES
32thyroxine46 2510.1AHR, GPT, IL5
33atorvastatin46 52 30 25 1213.1GPT, AHR
34vitamin d469.1AHR, GPT, IL5
35cyclosporin a46 30 6211.1GPT, ACTC1, IL5, CD46
36glutamine469.1IL5, GPT, AHR
37cycloheximide469.0CD46, IL5, AHR
38paraffin469.0CD46, IL5, ACTC1, DES
39steroid468.8ACTC1, AHR, DES
40tyrosine468.8DES, ACTC1, IL5, CD46
41dexamethasone46 52 30 1211.8AHR, ACTC1, IL5, CD46
42testosterone46 62 25 1211.7IL5, ACTC1, AHR, DES
43vegf468.7IL5, ACTC1, AHR, DES
44retinoic acid46 259.6IL5, ACTC1, AHR, DES
45adenylate468.5IL5, GPT, AHR, DES
46arginine468.5DES, AHR, GPT, IL5
47serine468.4DES, AHR, IL5, CD46

GO Terms for genes affiliated with Fasciitis

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17Gene Ontology
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Biological processes related to Fasciitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:0300499.5ACTC1, DES

Products for genes affiliated with Fasciitis

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  • Antibodies
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  • Antibodies

Sources for Fasciitis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet