MCID: FSC004
MIFTS: 50

Fasciitis malady

Summaries for Fasciitis

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 In medicine, fasciitis /ˌfæʃiˈaɪtɪs/ refers to an inflammation of the fascia, which is the... more...

MalaCards: Fasciitis is related to necrotizing fasciitis and plantar fasciitis. An important gene associated with Fasciitis is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways is Regulation of Wnt-mediated beta catenin signaling and target gene transcription. The compounds policosanol and alpha-hydroxybutyrate have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and thyroid, and related mouse phenotypes are cardiovascular system and mortality/aging.

Aliases & Classifications for Fasciitis

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 27ICD9CM, 39NCIt, 34MeSH, 56SNOMED-CT
See all sources

Aliases & Descriptions:

fasciitis 8 10 44 60


External Ids:

Disease Ontology8 DOID:9598
ICD9CM27 729.4
SNOMED-CT56 203123000, 36948007
NCIt39 C50559
MeSH34 D005208

Related Diseases for Fasciitis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Fasciitis:



Diseases related to fasciitis

Clinical Features for Fasciitis

About this section

Drugs & Therapeutics for Fasciitis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Fasciitis

Drug clinical trials:

Search ClinicalTrials for Fasciitis

Search NIH Clinical Center for Fasciitis

Search CenterWatch for Fasciitis

Genetic Tests for Fasciitis

About this section

Anatomical Context for Fasciitis

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Fasciitis:

32
Breast, Bone, Thyroid, Colon, Skin, Bone marrow, T cells, Kidney, Liver, Tonsil, Testes, Spinal cord, Small intestine, Smooth muscle, Monocytes, Myeloid, Lung, Lymph node, Pancreas, Prostate, Heart

Animal Models for Fasciitis or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Fasciitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053859.7CTNNB1, MED12, DES, TRPC4AP, AHR, ACTC1
2MP:00107689.1SPEG, CCNF, NPHS1, CTNNB1, PIK3C2A, MED12
3MP:00053769.1CTNNB1, FABP6, NPHS1, CARD9, PIK3C2A, DES

Publications for Fasciitis

About this section
Sources:
50PubMed
See all sources

Articles related to Fasciitis:

(show top 50)    (show all 1540)
idTitleAuthorsYear
1
Fulminant necrotizing fasciitis caused by Serratia marcescens in an immunosuppressed host. (22640271)
2014
2
Necrotizing fasciitis in a pediatric patient treated with etanercept and cyclosporine for macrophage activation syndrome. (22193231)
2013
3
Intravascular fasciitis of the lower lip. (23714904)
2013
4
Fatal necrotizing fasciitis following sclerotherapy for haemorrhoids. (23489816)
2013
5
Nodular fasciitis in the parotid gland: a case report and review of the literature. (23749727)
2013
6
Platelet-rich plasma injections for chronic plantar fasciitis. (23250352)
2013
7
Necrotizing fasciitis caused by Serratia marcescens: a fatal complication of nephrotic syndrome. (22401347)
2012
8
Necrotizing fasciitis caused by a variant of epidemic methicillin resistant Staphylococcus aureus -15. (23183478)
2012
9
Nodular fasciitis of the oro-facial region. (22629057)
2012
10
Managing chronic plantar fasciitis: when conservative strategies fail. (23620924)
2012
11
Primary necrotizing fasciitis of the breast: a case report and review of the literature. (22408223)
2012
12
Necrotizing fasciitis caused by Staphylococcus aureus: the emergence of methicillin-resistant strains. (21407055)
2011
13
Adapting a Vacuum Assisted Closure dressing to challenging wounds: negative pressure treatment for perineal necrotizing fasciitis with rectal prolapse in a newborn affected by acute myeloid leukaemia. (20406723)
2010
14
Necrotizing fasciitis caused by Haemophilus influenzae type E in a 17-year-old girl with systemic lupus erythematosus. (20051761)
2010
15
Necrotizing fasciitis following laparoscopic left hemicolectomy for diverticulitis. (19916772)
2010
16
Plantar fasciitis and impaired vision: A case report. (20952182)
2010
17
Immune cell subsets in necrotizing fasciitis: an immunohistochemical analysis. (19529958)
2009
18
Comparison of radial shockwaves and conventional physiotherapy for treating plantar fasciitis. (19219314)
2009
19
CD46 transgenic mouse model of necrotizing fasciitis caused by Streptococcus pyogenes infection. (19737905)
2009
20
Comparison of ultrasound-, palpation-, and scintigraphy-guided steroid injections in the treatment of plantar fasciitis. (18839190)
2009
21
Necrotizing fasciitis as the clinical presentation of a retroperitoneal abscess. (17976803)
2008
22
Eosinophilic fasciitis and toxic thyroid adenoma--a novel association. (18714852)
2008
23
Pathology quiz case 1. Diagnosis: nodular fasciitis of the medial canthus simulating dacryocystitis. (17709629)
2007
24
Plantar fasciitis: a review. (16498906)
2006
25
Eosinophilic fasciitis in a child mimicking a myopathy. (16427783)
2006
26
The role of hamstring tightness in plantar fasciitis. (16390645)
2005
27
Necrotizing fasciitis resulting from human bites: A report of two cases of disease caused by group A streptococcus. (18159548)
2005
28
The fasciitis-panniculitis syndrome presenting as complex regional pain syndrome type 1: report of a case. (15722813)
2005
29
Acquired amegakaryocytic thrombocytopenia purpura and eosinophilic fasciitis: a long relapsing and remitting course. (14978695)
2004
30
Low-energy extracorporeal shock-wave therapy for chronic plantar fasciitis. (12749302)
2003
31
JAMA patient page. Plantar fasciitis. (13129997)
2003
32
Paraneoplastic eosinophilic fasciitis: a case report. (12734672)
2003
33
A friend told me my heel pain is probably plantar fasciitis. What is this condition, and how is it treated? (12085780)
2002
34
Report of 2 fatal cases of adult necrotizing fasciitis and toxic shock syndrome caused by Streptococcus agalactiae. (11049806)
2000
35
Streptococcal toxic shock syndrome associated with necrotizing fasciitis. (10774464)
2000
36
Plantar fasciitis and other causes of heel pain. (10221305)
1999
37
Virulence of Streptococcus canis from canine streptococcal toxic shock syndrome and necrotizing fasciitis. (10591501)
1999
38
Systemic lupus erythematosus after eosinophilic fasciitis: a case report. (9704849)
1998
39
Necrotizing fasciitis in association with hyperimmunoglobulin E syndrome. (8537554)
1995
40
Eosinophilic fasciitis in children frequently progresses to scleroderma-like cutaneous fibrosis. (8441144)
1993
41
The eosinophilia-myalgia syndrome and eosinophilic fasciitis. (1772754)
1991
42
Eosinophilic fasciitis is clinically distinguishable from the eosinophilia-myalgia syndrome and is not associated with L-tryptophan use. (2023221)
1991
43
Proliferative fasciitis: ultrastructure and histogenesis. (2760292)
1989
44
Results of surgery in athletes with plantar fasciitis. (3804138)
1986
45
Eosinophilic fasciitis (Shulman syndrome) with prominent synovitis. (7107221)
1982
46
Carpal tunnel syndrome in cutaneous connective tissue disease: generalized morphea, lichen sclerosus, fasciitis, discoid lupus erythematosus, and lupus panniculitis. (7108001)
1982
47
Eosinophilic fasciitis: new associations and current perspectives. (7218260)
1981
48
Blood coagulation and fibrinolytic systems in patients with erysipelas and necrotizing fasciitis. (6787700)
1981
49
Plantar fasciitis and Achilles tendinitis among 150 cases of seronegative spondarthritis. (7209286)
1980
50
Eosinophilic fasciitis: a clinicopathologic study. (444327)
1979

Genetic Variations for Fasciitis

About this section

Expression for genes affiliated with Fasciitis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Fasciitis

Search GEO for disease gene expression data for Fasciitis.

Pathways for genes affiliated with Fasciitis

About this section
Sources:
37NCBI BioSystems Database
See all sources

Pathways related to Fasciitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2MYOG, MED12, CTNNB1

Compounds for genes affiliated with Fasciitis

About this section
Sources:
44Novoseek, 11DrugBank, 24HMDB, 28IUPHAR, 49PharmGKB, 59Tocris Bioscience
See all sources

Compounds related to Fasciitis according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1policosanol4410.7GPT, PIK3C2A
2alpha-hydroxybutyrate4410.6GPT, PIK3C2A
3orcein4410.6ACTC1, DES
4unicap4410.6IL5, IGHE
5omalizumab44 1111.6IGHE, IL5
6oxatomide4410.6IGHE, IL5
7ovomucoid4410.6IGHE
8methylcellulose4410.6IL5, AHR, CTNNB1
9s 1004410.6ACTC1, DES
10d-galactosamine4410.6GPT, DES
11glycogen44 2411.6ACTC1, PIK3C2A, CTNNB1
12gemfibrozil44 28 1112.6GPT, PIK3C2A, DES
13bezafibrate44 28 1112.6GPT, PIK3C2A, DES
14beclomethasone dipropionate4410.6IGHE, IL5
15estrogen4410.5MYOG
16imatinib44 49 1112.5ACTC1, IL5, DES, CTNNB1
17p-0074410.5GPT, PIK3C2A
18fenofibrate44 49 1112.5DES, PIK3C2A, GPT
19ivig4410.5IGHE, PIK3C2A, GPT, IL5
20prednisolone44 28 1112.5IL5, PIK3C2A, IGHE, GPT
21toluene diisocyanate4410.4IGHE, IL5
22glycerol44 11 2412.4AHR, IGHE, PIK3C2A, CTNNB1
23methotrexate44 49 1112.4PIK3C2A, GPT, IL5, IGHE
24vitamin d4410.4AHR, GPT, IL5, CTNNB1, IGHE
25thyroxine44 2411.4GPT, PIK3C2A, IGHE, AHR, IL5
26sodium cromoglycate4410.4IGHE, IL5
27paraffin4410.4MYOG, ACTC1, IL5, CTNNB1, CD46, DES
28glutamine4410.3GPT, IL5, AHR, IGHE, CTNNB1
29pge14410.3IGHE, GPT, PIK3C2A
30fatty acid4410.3DES, CTNNB1, PIK3C2A, MYOG, FABP6
31cyclosporin a44 28 5912.3CD46, IL5, ACTC1, GPT, PIK3C2A, IGHE
32adenylate4410.3DES, IL5, IGHE, MYOG, AHR, GPT
33n acetylcysteine4410.3GPT, IGHE, AHR, CTNNB1
34cetirizine44 28 11 2413.3IGHE, IL5
35phenobarbital44 28 1112.2CTNNB1, AHR, GPT
36dexamethasone44 49 28 1113.2IGHE, CTNNB1, AHR, IL5, NPHS1, ACTC1
37aspartate4410.2AHR, GPT, PIK3C2A, CTNNB1, IGHE
38steroid4410.2CTNNB1, PIK3C2A, NPHS1, AHR, MYOG, DES
39ascorbic acid44 2411.2PIK3C2A, IGHE, AHR, MYOG
40creatinine4410.2PIK3C2A, DES, IGHE, MYOG, NPHS1, ACTC1
41glycocholate4410.2GPT, FABP6
42glutamate4410.2IGHE, PIK3C2A, IL5, CTNNB1, GPT, AHR
43alanine4410.2CD46, IGHE, PIK3C2A, CTNNB1, GPT, AHR
44retinoic acid44 2411.1ACTC1, MYOG, AHR, IGHE, NPHS1, DES
45testosterone44 59 11 2413.1DES, IGHE, MYOG, AHR, PIK3C2A, IL5
46arginine4410.1IGHE, IL5, AHR, DES, PIK3C2A, GPT
47tyrosine4410.1IL5, MYOG, DES, PIK3C2A, CTNNB1, CD46
48vegf4410.0MYOG, ACTC1, IL5, IGHE, PIK3C2A, CTNNB1
49progesterone44 59 28 11 2414.0CTNNB1, PIK3C2A, DES, CD46, ACTC1
50glucose449.6DES, MYOG, PIK3C2A, NPHS1, GPT, ACTC1

GO Terms for genes affiliated with Fasciitis

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Fasciitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1fascia adherensGO:00591610.3DES, CTNNB1
2protein-DNA complexGO:03299310.0MYOG, CTNNB1

Products for genes affiliated with Fasciitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Fasciitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet