MCID: FTT001
MIFTS: 44

Fatty Liver Disease malady

Gastrointestinal diseases, Metabolic diseases, Liver diseases categories
Download this MalaCard

Summaries for Fatty Liver Disease

About this section


Fully expand this MalaCard
MalaCards based summary: Fatty Liver Disease, also known as fatty change of liver, is related to liver disease and acute fatty liver of pregnancy. An important gene associated with Fatty Liver Disease is PNPLA3 (patatin-like phospholipase domain containing 3), and among its related pathways is Cardiac muscle contraction. The compound phenobarbital have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and adipocyte.

Aliases & Classifications for Fatty Liver Disease

About this section
Sources:
8Disease Ontology, 10DISEASES, 62UMLS, 44Novoseek, 57SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
See all sources

Fatty Liver Disease, Aliases & Descriptions:

Name: Fatty Liver Disease 8 10
Fatty Change of Liver 8 62
Hepatic Lipidosis 8 62
Fatty Liver 44 62
Fatty Liver, Alcoholic 62
 
Alcoholic Fatty Liver 8
Fatty Liver Alcoholic 44
Steatosis of Liver 8
Fatty Degeneration 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Metabolic diseases
Anatomical: Gastrointestinal diseases, Liver diseases


External Ids:

Disease Ontology8 DOID:9452
ICD9CM27 571.0
ICD1025 K70.0, K76.0

Related Diseases for Fatty Liver Disease

About this section

Graphical network of the top 20 diseases related to Fatty Liver Disease:



Diseases related to fatty liver disease

Symptoms for Fatty Liver Disease

About this section

Drugs & Therapeutics for Fatty Liver Disease

About this section

Drug clinical trials:

Search ClinicalTrials for Fatty Liver Disease

Search NIH Clinical Center for Fatty Liver Disease

Genetic Tests for Fatty Liver Disease

About this section

Anatomical Context for Fatty Liver Disease

About this section

MalaCards organs/tissues related to Fatty Liver Disease:

32
Liver, Heart, Adipocyte, Endothelial, Kidney, Testes, Ovary, Bone, Skeletal muscle, Thyroid, Whole blood, Brain, Pancreas, Prostate

Animal Models for Fatty Liver Disease or affiliated genes

About this section

Publications for Fatty Liver Disease

About this section

Articles related to Fatty Liver Disease:

(show top 50)    (show all 1055)
idTitleAuthorsYear
1
Nonalcoholic Fatty Liver Disease and Hyperuricemia: A Close Relation with Hepatic Insulin Resistance after Nicotinic Acid Treatment? (25350520)
2014
2
Acceleration training for managing nonalcoholic fatty liver disease: a pilot study. (25404857)
2014
3
Systems biology approaches for studying the pathogenesis of non-alcoholic fatty liver disease. (25386055)
2014
4
Dietary capsaicin prevents nonalcoholic fatty liver disease through transient receptor potential vanilloid 1-mediated peroxisome proliferator-activated receptor I' activation. (23605066)
2013
5
Pediatric non-alcoholic fatty liver disease: an increasing public health issue. (24068459)
2013
6
miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease. (22902550)
2013
7
Simple noninvasive systems predict long-term outcomes of patients with nonalcoholic fatty liver disease. (23860502)
2013
8
Oral probiotic microcapsule formulation ameliorates non-alcoholic fatty liver disease in Bio F1B Golden Syrian hamsters. (23554890)
2013
9
Efficacy of Tumor Necrosis Factor and Interleukin-10 Analysis in the Follow-up of Nonalcoholic Fatty Liver Disease Progression. (24426199)
2013
10
Characterization of European ancestry nonalcoholic fatty liver disease-associated variants in individuals of African and Hispanic descent. (23564467)
2013
11
Abnormality of Autophagic Function and Cathepsin Expression in the Liver from Patients with Non-alcoholic fatty liver disease. (24299564)
2013
12
IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice. (24115079)
2013
13
Expression of cytochrome P450 2A5 in a C57BL/6J mouse model of nonalcoholic fatty liver disease. (23867551)
2013
14
Coffee enhances the expression of chaperones and antioxidant proteins in rats with nonalcoholic fatty liver disease. (24365744)
2013
15
Blood urea nitrogen is elevated in patients with non-alcoholic fatty liver disease. (23858556)
2013
16
Association between liver-specific gene polymorphisms and their expression levels with nonalcoholic fatty liver disease. (23213074)
2013
17
Treatment of non-alcoholic fatty liver disease: can we already face the epidemic? (23898557)
2013
18
Pediatric non alcoholic fatty liver disease: old and new concepts on development, progression, metabolic insight and potential treatment targets. (23530957)
2013
19
Chronic kidney disease and nonalcoholic Fatty liver disease proven by transient elastography. (24029696)
2013
20
Analysis of cytotoxic T-lymphocyte-associated antigen-4 and MMP-9 genes' methylation and their expression profiles with risk of non-alcoholic fatty liver disease. (24019613)
2013
21
Non-alcoholic fatty liver disease is not associated with vitamin D deficiency in essential hypertension. (23584921)
2013
22
Nonalcoholic fatty liver disease is associated with increased GHBP and reduced GH/IGF-I levels. (22077984)
2012
23
Expression of MCP-1 in the patients of chronic hepatitis B complicated with nonalcoholic fatty liver disease]. (22980664)
2012
24
Concentrations of connective tissue growth factor in patients with nonalcoholic fatty liver disease: association with liver fibrosis. (22846210)
2012
25
Lack of association between peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms and progressive liver damage in patients with non-alcoholic fatty liver disease: a case control study. (20825652)
2010
26
Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. (19523535)
2009
27
Expression of adiponectin and its receptors in livers of morbidly obese patients with non-alcoholic fatty liver disease. (18713296)
2009
28
The effect of metformin on leptin in obese patients with type 2 diabetes mellitus and nonalcoholic fatty liver disease. (18839053)
2009
29
Prescribing statins to patients with nonalcoholic fatty liver disease: real cardiovascular benefits outweigh theoretical hepatotoxic risk. (19555426)
2009
30
Efficacy and safety of ezetimibe/simvastatin combination therapy in patients with type 2 diabetes and nonalcoholic fatty liver disease]. (19443308)
2009
31
The multi-hit process and the antagonistic roles of tumor necrosis factor-alpha and adiponectin in non alcoholic fatty liver disease. (19561788)
2009
32
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors. (19524579)
2009
33
The evolution of ideas about nonalcohol fatty liver disease]. (19967814)
2009
34
Abdominal adipose area, serum adiponectin and leptin levels of nonalcoholic fatty liver disease in elderly males.]. (19254460)
2009
35
Soft drink consumption is associated with fatty liver disease independent of metabolic syndrome. (19765850)
2009
36
Gene expression profile associated with superimposed non-alcoholic fatty liver disease and hepatic fibrosis in patients with chronic hepatitis C. (19515216)
2009
37
Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. (18242210)
2008
38
Peroxisome proliferator-activated receptor gamma: a common link for non-alcoholic fatty liver disease and colorectal cancer? (17482764)
2007
39
The prevalence of peripheral iron overload and the presence of HFE gene (H63D) mutation among the Korean patients with nonalcoholic fatty liver disease]. (17585191)
2007
40
Methylenetetrahydrofolate reductase C677T mutation and nonalcoholic fatty liver disease. (17356914)
2007
41
Gene expression patterns in hepatic tissue and visceral adipose tissue of patients with non-alcoholic fatty liver disease. (17953248)
2007
42
Non-invasive markers to predict the liver fibrosis in non-alcoholic fatty liver disease. (16911470)
2006
43
Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2. (16618517)
2006
44
In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease. (16799979)
2006
45
Nonalcoholic fatty liver disease in India--is it different? (17542290)
2006
46
Association between tumor necrosis factor-alpha gene polymorphism and insulin resistance in nonalcoholic fatty liver disease]. (16938178)
2006
47
Association of serum leptin and insulin resistance with nonalcoholic fatty liver disease]. (16793619)
2006
48
The role of PPAR alpha in the pathogenesis of fatty liver disease]. (16174475)
2005
49
Management of fatty liver disease with vitamin E and C compared to ursodeoxycholic acid treatment. (16245220)
2005
50
Leptin and fatty liver disease]. (15329225)
2004

Variations for Fatty Liver Disease

About this section

Expression for genes affiliated with Fatty Liver Disease

About this section
Expression patterns in normal tissues for genes affiliated with Fatty Liver Disease

Search GEO for disease gene expression data for Fatty Liver Disease.

Pathways for genes affiliated with Fatty Liver Disease

About this section

Pathways related to Fatty Liver Disease according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4UQCRHL, COX8C

Compounds for genes affiliated with Fatty Liver Disease

About this section
Sources:
44Novoseek, 28IUPHAR, 50PharmGKB, 11DrugBank
See all sources

Compounds related to Fatty Liver Disease according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1phenobarbital44 28 50 1112.8GPT, CYP2A

GO Terms for genes affiliated with Fatty Liver Disease

About this section

Products for genes affiliated with Fatty Liver Disease

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Fatty Liver Disease

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet