Aliases & Classifications for Fecal Incontinence

Aliases & Descriptions for Fecal Incontinence:

Name: Fecal Incontinence 38 69

Summaries for Fecal Incontinence

MalaCards based summary : Fecal Incontinence is related to pudendal neuralgia and steatorrhea, and has symptoms including abdominal pain, cachexia and constipation. The drugs Glycerol and Loperamide have been mentioned in the context of this disorder. Affiliated tissues include Adipose and Adipose.

Wikipedia : 71 Fecal incontinence (FI), also called faecal incontinence, bowel incontinence, anal incontinence,... more...

Related Diseases for Fecal Incontinence

Graphical network of the top 20 diseases related to Fecal Incontinence:



Diseases related to Fecal Incontinence

Symptoms & Phenotypes for Fecal Incontinence

UMLS symptoms related to Fecal Incontinence:


abdominal pain, cachexia, constipation, cyanosis, diarrhea, dyspepsia, dyspnea, edema, fever, flatulence, eructation, and gas pain, headache, heartburn, icterus, nausea and vomiting, seizures, signs and symptoms, signs and symptoms, digestive, syncope, vertigo, symptoms involving digestive system, other symptoms involving digestive system, rectal tenesmus, bowel urgency, gastrointestinal gas, hot flushes, colonic inertia, disturbance in bowel function, symptoms, full incontinence of feces

Drugs & Therapeutics for Fecal Incontinence

Drugs for Fecal Incontinence (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 209)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Glycerol Approved, Experimental Phase 4 56-81-5 753
2
Loperamide Approved Phase 4,Phase 2,Phase 3 53179-11-6 3955
3
Lubiprostone Approved, Investigational Phase 4,Phase 3 136790-76-6 656719
4
Bisacodyl Approved Phase 4,Phase 2 603-50-9
5 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
6 Antacids Phase 4
7 Anti-Ulcer Agents Phase 4
8 Antidiarrheals Phase 4,Phase 2,Phase 3
9 Calcium polycarbophil Phase 4,Phase 2,Phase 3
10 Calcium, Dietary Phase 4,Phase 2,Phase 3
11 Cathartics Phase 4,Phase 2,Phase 3
12 Laxatives Phase 4,Phase 2,Phase 3
13 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3,Phase 1
14 Protective Agents Phase 4,Phase 3,Phase 1,Phase 2
15 Polyethylene glycol 3350 Phase 4,Phase 3
16 Acidophilus Nutraceutical Phase 4,Phase 2
17 Cola Nutraceutical Phase 4,Phase 3,Phase 1
18 Psyllium Nutraceutical Phase 4,Phase 2,Phase 3
19
Acetylcholine Approved Phase 3,Phase 2 51-84-3 187
20
Menthol Approved Phase 3,Phase 1 2216-51-5 16666
21
Lactulose Approved Phase 3 4618-18-2 11333
22
Metronidazole Approved Phase 3 443-48-1 4173
23
Carboplatin Approved Phase 3 41575-94-4 10339178 498142 38904
24
Pemetrexed Approved, Investigational Phase 3 150399-23-8, 137281-23-3 446556 60843
25
Bismuth Subsalicylate Approved, Vet_approved Phase 2, Phase 3 14882-18-9 53629521
26
Clonidine Approved Phase 3,Phase 2 4205-90-7 2803
27
Fluorouracil Approved Phase 3,Phase 2 51-21-8 3385
28
Ephedrine Approved Phase 3,Phase 1,Phase 2 299-42-3 9294
29
Oxymetazoline Approved Phase 3,Phase 1,Phase 2 1491-59-4 4636
30
Phenylephrine Approved Phase 3,Phase 1,Phase 2 59-42-7 6041
31
Pseudoephedrine Approved Phase 3,Phase 1,Phase 2 90-82-4 7028
32
Cyproterone Acetate Approved, Investigational Phase 3 427-51-0
33
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757 53477783
34
Imiquimod Approved, Investigational Phase 3 99011-02-6 57469
35
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
36
leucovorin Approved, Nutraceutical Phase 3 58-05-9 54575, 6560146 143
37
Docetaxel Approved May 1996, Investigational Phase 3 114977-28-5 148124 9877265
38 Coagulants Phase 3,Phase 1
39 Fibrin Tissue Adhesive Phase 3,Phase 1
40 Hemostatics Phase 3,Phase 1
41 abobotulinumtoxinA Phase 3,Phase 2
42 Botulinum Toxins Phase 3,Phase 2
43 Botulinum Toxins, Type A Phase 3,Phase 2
44 Cholinergic Agents Phase 3,Phase 2,Phase 1
45 incobotulinumtoxinA Phase 3,Phase 2
46 Neuromuscular Agents Phase 3,Phase 2
47 Neurotransmitter Agents Phase 3,Phase 2,Phase 1
48 onabotulinumtoxinA Phase 3,Phase 2
49 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
50 Anesthetics Phase 3,Phase 1,Phase 2

Interventional clinical trials:

(show top 50) (show all 297)
id Name Status NCT ID Phase
1 Lactobacillus Reuteri in Children With Constipation Unknown status NCT01388712 Phase 4
2 Polyethylene Glycol for Childhood Constipation Unknown status NCT01875744 Phase 4
3 Treatment of Fecal Incontinence and Constipation in Patients With Spinal Cord Injury Completed NCT00286520 Phase 4
4 Sacral Nerve Stimulation for Anal Incontinence and Bowel Control Completed NCT00200005 Phase 4
5 Polyacrylamide Hydrogel Injection Treatment for Anal Incontinence Completed NCT02550899 Phase 4
6 A Modified Surgical Approach to Women With Obstetric Anal Sphincter Tears Completed NCT01021722 Phase 4
7 Short Protocol Barostat for Assessment of Anorectal Function Versus Standard Protocol Barostat in Healthy Volunteers Completed NCT01456442 Phase 4
8 Psyllium Fiber Versus Placebo in Early Treatment After STARR for Obstructed Defecation: a Double-blind RCT Completed NCT02136693 Phase 4
9 Safety and Efficacy of Lubiprostone in Pediatric Patients With Constipation Completed NCT00452335 Phase 4
10 A Study to Compare the Effect of Transipeg 2.95 g or Forlax Junior 4 g in Children With Constipation Completed NCT01810653 Phase 4
11 A Within Subjects Comparison of Two Antegrade Flushing Regimens in Children Recruiting NCT02435069 Phase 4
12 HAL-RAR Versus Hemorrhoidectomy in the Treatment of Grade III-IV Hemorrhoids. Prospective, Randomized Trial Recruiting NCT02216305 Phase 4
13 Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome Recruiting NCT01312259 Phase 4
14 The Bowel CLEAnsing: A National Initiative Recruiting NCT02547571 Phase 4
15 Clinical Use of a Magnetic Anal Sphincter Augmentation Device, Trade Name FENIX Available NCT02722707 Phase 4
16 Urotherapy vs. Urotherapy With Constipation Treatment for Children With Lower Urinary Tract Dysfunction Not yet recruiting NCT02336906 Phase 4
17 Urotherapy vs. Urotherapy With Constipation Treatment for Nocturnal Enuresis Not yet recruiting NCT02337413 Phase 4
18 Comparison of Esophageal and Anorectal Manometry Catheters Terminated NCT00204763 Phase 4
19 Imodium Syrup Versus Imodium Tablets for Faecal Incontinence Withdrawn NCT00933465 Phase 4
20 Ligation of Intersphincteric Fistula Tract (LIFT) Versus LIFT-plug Procedure for Anal Fistula Repair Unknown status NCT01478139 Phase 3
21 Efficacy and Mechanisms of Pharmacologic Treatment of Fecal Incontinence Completed NCT00727649 Phase 2, Phase 3
22 Percutaneous Tibial Nerve Stimulation in the Treatment of Fecal Incontinence Completed NCT00974909 Phase 3
23 UK Trial of Percutaneous Tibial Nerve Stimulation in Patients With Faecal Incontinence Completed NCT02349334 Phase 3
24 Autologous Myoblast Intrasphincteric Injection for Fecal Incontinence Completed NCT01523522 Phase 2, Phase 3
25 Controlling Anal Incontinence by Performing Anal Exercises With Biofeedback or Loperamide (CAPABLe) Completed NCT02008565 Phase 3
26 Triple Target Treatment (3T) Which Combines Stimulation With Amplitude Modulated Middle Frequency (AM-MF), Electromyography (EMG)-Triggered Stimulation and EMG-Biofeedback Compared With EMG-Biofeedback in Anal Incontinence Completed NCT00525291 Phase 3
27 Behavioral Therapy Of Obstetric Sphincter Tears Completed NCT01166399 Phase 3
28 To Determine the Effect of Forlax® Treatment in Children With Chronic Constipation Who May Also Suffer From Soiling/ Faecal Incontinence. Completed NCT00255372 Phase 3
29 Does the Negativation of the Glucose Hydrogen Breath Test Come Along With a Reduction of the Symptoms of Gaz Incontinence ? Completed NCT01275560 Phase 3
30 Prenatal Pelvic Floor Prevention (3PN) Completed NCT00551551 Phase 3
31 Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation Completed NCT02163187 Phase 2, Phase 3
32 Trial Involving Subjects Over 70 Years of Age With Non Small-cell Lung Cancer of Stage IV and Comparing a "Classical" Strategy of Treatment Allocation, With an"Optimized" Strategy Allocating the Same Treatments Completed NCT01257139 Phase 3
33 Efficacy and Safety of Adipose Stem Cells to Treat Complex Perianal Fistulas Not Associated to Crohn´s Disease Completed NCT00475410 Phase 3
34 Prucalopride in Pediatric Subjects With Functional Constipation Completed NCT01330381 Phase 3
35 Pelvic Floor Muscle Training and Biofeedback or Standard Therapy in Men Who Have Undergone Radical Prostatectomy or Transurethral Resection of the Prostate Completed NCT00632138 Phase 3
36 Study to Examine the Efficacy and Safety of Movicol in the Treatment of Chronic Constipation in Children Completed NCT00403819 Phase 3
37 An Open Single Centre Study To Assess Treatment of Chronic Constipation in Children Completed NCT00403897 Phase 3
38 The Use of SennaS for Prevention of Post-operative Constipation After Urogynecologic Surgery Completed NCT00571896 Phase 2, Phase 3
39 Efficacy, Safety, and Tolerability of JNJ-27018966 in the Treatment of Patients With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d) (Protocol JNJ-27018966IBS3001) Completed NCT01553591 Phase 3
40 Efficacy, Safety, and Tolerability of JNJ-27018966 in the Treatment of Patients With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d) (Protocol JNJ-27018966IBS3002) Completed NCT01553747 Phase 3
41 Efficacy and Safety of Lubiprostone in Pediatric Subjects Aged ≥ 6 Years to < 18 Years With Functional Constipation Completed NCT02042183 Phase 3
42 Effect and Tolerance of Botulinum A Toxin Rectal Injections on Fecal Incontinence Recruiting NCT02414425 Phase 3
43 A Study of Colesevelam in Fecal Incontinence Recruiting NCT02628626 Phase 3
44 Therapeutic Management of Complex Anal Fistulas by Installing a Closure Clip: Multicentre Randomized Controlled Trial Recruiting NCT02336867 Phase 2, Phase 3
45 MEdical Versus SUrgical Treatments of Rectal Endometriosis Recruiting NCT01973816 Phase 3
46 Topical or Ablative Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Squamous Intraepithelial Lesions Recruiting NCT02135419 Phase 3
47 Long-term Safety and Efficacy of Lubiprostone in Subjects Aged ≥ 6 Years to < 18 Years With Functional Constipation Active, not recruiting NCT02138136 Phase 3
48 Bulking Agent Versus Electrostimulation Therapy in Anal Incontinence Not yet recruiting NCT03052946 Phase 2, Phase 3
49 Feasibility Study to Assess the Early Use of Porcine Cross-linked Collagen Paste in Cryptoglandular Anorectal Fistulas Not yet recruiting NCT02686580 Phase 3
50 Gore-BioA Fistula Plug to Treat Transsphincteric Fistulas Terminated NCT01584752 Phase 3

Search NIH Clinical Center for Fecal Incontinence

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Fecal Incontinence cell therapies at LifeMap Discovery.

Genetic Tests for Fecal Incontinence

Anatomical Context for Fecal Incontinence

MalaCards organs/tissues related to Fecal Incontinence:

39
Testes, Colon, Prostate, Skin, Kidney, Brain, Spinal Cord
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Fecal Incontinence:
id Tissue Anatomical CompartmentCell Relevance
1 Adipose Subcutaneous White Adipose Mesenchymal Stem Cells Potential therapeutic candidate
2 Adipose Subcutaneous White Adipose Stromal Cells Potential therapeutic candidate

Publications for Fecal Incontinence

Articles related to Fecal Incontinence:

(show top 50) (show all 598)
id Title Authors Year
1
Long-term Experience of Magnetic Anal Sphincter Augmentation in Patients With Fecal Incontinence. ( 27926562 )
2017
2
Contemporary short- and long-term outcomes in patients with unremitting constipation and fecal incontinence treated with an antegrade continence enema. ( 27817835 )
2017
3
Neurostimulation for fecal incontinence after correction of repair of imperforate anus. ( 28352637 )
2017
4
Rationale for Investigating Stool Metabolites and Microbiota in Women With Fecal Incontinence. ( 28059923 )
2017
5
Novel insights into fecal incontinence in men. ( 27881404 )
2017
6
How to Size the Anal Canal Circumference When Implanting a Magnetic Anal Sphincter for Fecal Incontinence. Evolution and Update of a New Surgical Technique. ( 27505121 )
2016
7
Effect of bariatric surgery on urinary and fecal incontinence: prospective analysis with 1-year follow-up. ( 27639987 )
2016
8
Shared Risk Factors for Constipation, Fecal Incontinence, and Combined Symptoms in Older U.S. Adults. ( 27783401 )
2016
9
Characteristics of the Contrast Enema Do Not Predict an Effective Bowel Management Regimen for Patients with Constipation or Fecal Incontinence. ( 27688984 )
2016
10
Dynamic Article: Percutaneous Nerve Evaluation Versus Staged Sacral Nerve Stimulation for Fecal Incontinence. ( 27602927 )
2016
11
Evidence-Based Update on Treatments of Fecal Incontinence in Women. ( 26880511 )
2016
12
Incontinence-Associated Dermatitis in Nursing Homes: Prevalence, Severity, and Risk Factors in Residents With Urinary and/or Fecal Incontinence. ( 27749788 )
2016
13
Pelvic floor muscle exercise for fecal incontinence quality of life after coloanal anastomosis. ( 27461451 )
2016
14
The fecal incontinence quality of life scale (FIQL) and fecal incontinence severity index (FISI): Validation of the Dutch versions. ( 27028557 )
2016
15
Validation of the Fecal Incontinence Severity Index in a Turkish Population. ( 26945267 )
2016
16
Adverse events of sacral neuromodulation for fecal incontinence reported to the federal drug administration. ( 27158546 )
2016
17
Usefulness of anorectal and endovaginal 3D ultrasound in the evaluation of sphincter and pubovisceral muscle defects using a new scoring system in women with fecal incontinence after vaginal delivery. ( 28035460 )
2016
18
Managing fecal incontinence in patients with myelomeningocele in Sub-Saharan Africa: Role of antegrade continence enema (ACE). ( 27634558 )
2016
19
Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment. ( 26926695 )
2016
20
Normal tissue complication probability (NTCP) models for late rectal bleeding, stool frequency and fecal incontinence after radiotherapy in prostate cancer patients. ( 27157889 )
2016
21
A Predictive Model to Identify Patients With Fecal Incontinence Based on High-definition Anorectal Manometry. ( 27464594 )
2016
22
Urinary incontinence, but not fecal incontinence, is a risk factor for admission to aged residential care of older persons in New Zealand. ( 27778373 )
2016
23
Current Trends in Management of Defecatory Dysfunction, Posterior Compartment Prolapse, and Fecal Incontinence. ( 27547494 )
2016
24
Systematic Review of Surgical Treatments for Fecal Incontinence. ( 27050607 )
2016
25
Safety and Efficacy of Permacol Injection in the Treatment of Fecal Incontinence. ( 27218098 )
2016
26
Sacral nerve stimulation for fecal incontinence in a patient with anti-phospholipid syndrome-related autonomic neuropathy. ( 26670782 )
2016
27
Reproducibility of high-definition (3D) manometry and its agreement with high-resolution (2D) manometry in women with fecal incontinence. ( 27696628 )
2016
28
Prevalence of Fecal Incontinence in the Acute Care Setting. ( 27607748 )
2016
29
Fecal incontinence among nursing home residents: Is it still a problem? ( 27010346 )
2016
30
Health Related Quality of Life and Parental Stress in Children with Fecal Incontinence: A Normative Comparison. ( 27027905 )
2016
31
Damaged anal canal as a cause of fecal incontinence after surgical repair for Hirschsprung disease - a preventable and under-reported complication. ( 27624566 )
2016
32
Re: Prevalence of Fecal Incontinence (FI) and Associated Factors in Institutionalized Older Adults. ( 27628815 )
2016
33
Improving biofeedback for the treatment of fecal incontinence in women: implementation of a standardized multi-site manometric biofeedback protocol. ( 27453154 )
2016
34
Validating endpoints for therapeutic trials in fecal incontinence. ( 26948292 )
2016
35
Treating Fecal Incontinence: An Unmet Need in Primary Care Medicine. ( 27154893 )
2016
36
Sacral nerve stimulation versus percutaneous posterior tibial nerve stimulation in the treatment of severe fecal incontinence in men. ( 26925981 )
2016
37
Fecal Incontinence: Epidemiology, Impact, and Treatment. ( 27582653 )
2016
38
Eliciting Help-Seeking Behaviors in Patients With Fecal Incontinence: Supporting Timely Access to Treatment. ( 27580281 )
2016
39
On the prevalence of constipation and fecal incontinence, and their co-occurrence, in the Netherlands. ( 27913883 )
2016
40
Irritable Bowel Syndrome and Quality of Life in Women With Fecal Incontinence. ( 27918339 )
2016
41
Effect of age, patient's sex, and type of trauma on the correlation between size of sphincter defect and anal pressures in posttraumatic fecal incontinence. ( 27392390 )
2016
42
Role of diet in fecal incontinence: a systematic review of the literature. ( 26883367 )
2016
43
Efficacy of Biofeedback Therapy before and after Sphincteroplasty for Fecal Incontinence because of Obstetric Injury: A Randomized Controlled Trial. ( 26989283 )
2016
44
Integrated low-intensity biofeedback therapy in fecal incontinence: evidence that "good" in-home anal sphincter exercise practice makes perfect. ( 27440584 )
2016
45
Prospective cohort study of phenotypic variation based on an anal sphincter function in adults with fecal incontinence. ( 27144375 )
2016
46
A Content Incontinent: Report of Liposomal Bupivacaine Induced Fecal Incontinence. ( 27747127 )
2016
47
Efficacy of anorectal biofeedback in scleroderma patients with fecal incontinence: a case-control study. ( 27686130 )
2016
48
Characteristics Associated With Successful Fitting of a Vaginal Bowel Control System for Fecal Incontinence. ( 27564386 )
2016
49
Role of Permacol Injection in the Treatment of Patients With Fecal Incontinence. ( 27218094 )
2016
50
Fecal incontinence: A review of current treatment options. ( 27580000 )
2016

Variations for Fecal Incontinence

Expression for Fecal Incontinence

Search GEO for disease gene expression data for Fecal Incontinence.

Pathways for Fecal Incontinence

GO Terms for Fecal Incontinence

Sources for Fecal Incontinence

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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