MCID: FML039
MIFTS: 46

Female Reproductive System Disease

Categories: Reproductive diseases

Aliases & Classifications for Female Reproductive System Disease

MalaCards integrated aliases for Female Reproductive System Disease:

Name: Female Reproductive System Disease 12 14
Female Reproductive System Disorder 69
Genital Diseases, Female 42

Classifications:



External Ids:

Disease Ontology 12 DOID:229
ICD9CM 35 629.9
MeSH 42 D005831
UMLS 69 C0017411

Summaries for Female Reproductive System Disease

Disease Ontology : 12 A reproductive system disease that impairs the ability to reproduce and is located in the uterus, vagina, cervix, ovaries or fallopian tubes.

MalaCards based summary : Female Reproductive System Disease, also known as female reproductive system disorder, is related to african histoplasmosis and polyneuropathy, and has symptoms including leukorrhea, mastodynia and genital itching. An important gene associated with Female Reproductive System Disease is AMH (Anti-Mullerian Hormone), and among its related pathways/superpathways are NF-KappaB Family Pathway and Glucocorticoid receptor regulatory network. The drugs Selenium and Metformin have been mentioned in the context of this disorder. Affiliated tissues include ovary, testes and uterus, and related phenotypes are endocrine/exocrine gland and homeostasis/metabolism

Wikipedia : 72 The female reproductive system (or female genital system) is made up of the internal and external sex... more...

Related Diseases for Female Reproductive System Disease

Diseases related to Female Reproductive System Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 102)
id Related Disease Score Top Affiliating Genes
1 african histoplasmosis 11.0 GNRH1 PRL
2 polyneuropathy 10.9 CYP19A1 SHBG
3 prostate leiomyoma 10.9 GNRH1 PRL
4 skin sarcoma 10.9 PGR PRL
5 perinatal jaundice due to hepatocellular damage 10.9 AMH CYP19A1 PGR
6 mitochondrial complex iii deficiency, nuclear type 9 10.9 BMP15 CYP19A1
7 internal hemorrhoid 10.9 GNRH1 PRL SHBG
8 precocious puberty, male 10.9 CYP19A1 FSHR
9 oculomotor nerve paralysis 10.9 CXCL8 IL6
10 adenomatoid tumor 10.9 GNRH1 PRL
11 glioblastoma proneural subtype 10.9 CYP19A1 PRL SHBG
12 common peroneal nerve lesion 10.8 CXCL8 IL6
13 osteopathia striata with cranial sclerosis 10.8 CYP19A1 SHBG
14 ectopic pregnancy 10.8
15 endometriosis 10.8
16 uterine disease 10.8
17 hypogonadism 10.8 CYP19A1 FOXL2 PGR
18 infancy electroclinical syndrome 10.8 CXCL8 IL6 SERPINH1
19 osteogenesis imperfecta, type x 10.8 CXCL8 IL6 SERPINH1
20 bullous retinoschisis 10.8 CXCL8 IL6 SERPINH1
21 carbuncle 10.8 CXCL8 IL6 SERPINH1
22 acquired thrombocytopenia 10.8 CXCL8 IL6 TRPV1
23 gonococcal keratitis 10.8 IL6 SERPINH1
24 ovarian hyperstimulation syndrome 10.8 AMH CYP19A1 FSHR GNRH1
25 uterine corpus dissecting leiomyoma 10.8 CXCL8 IL6 TRPV1
26 retroperitoneal sarcoma 10.8 AMH GNRH1 PRL SHBG
27 tetrahydrobiopterin-responsive hyperphenylalaninemia/phenylketonuria 10.8 CYP19A1 PGR TLR9
28 munchausen by proxy 10.8 OXT PRL SHBG
29 eyelid neoplasm 10.8 CXCL8 TLR9 TRPV1
30 plague 10.8 PGR PRL SHBG
31 neovascular glaucoma 10.8 CXCL8 IL6 TRPV1
32 dehydration polycythemia 10.8 CXCL8 TLR9 TRPV1
33 inherited metabolic disorder 10.8 IL6 SHBG TRPV1
34 pervasive developmental disorder 10.8 FMR1 OXT TRPV1
35 pelvic varices 10.8 CXCL8 TLR9 TRPV1
36 haverhill fever 10.8 CYP19A1 GNRH1 PGR PRL
37 black piedra 10.8 CYP19A1 GNRH1 PGR
38 pelvic muscle wasting 10.8 CYP19A1 GNRH1 PRL SHBG
39 capillary lymphangioma 10.7 AMH FSHR GNRH1 SHBG
40 lymphoma 10.7 IL6 TLR9 TRPV1
41 peroneal nerve paralysis 10.7 IL6 TLR9
42 bacterial gastritis 10.7 IL6 TLR9 TRPV1
43 spermatogenic failure, y-linked, 1 10.7 BMP15 FSHR
44 thymus mucoepidermoid carcinoma 10.7 AMH BMP15 GNRH1 OXT
45 ulceroglandular tularemia 10.7 OXT SHBG
46 her2-receptor positive breast cancer 10.7 CYP19A1 PGR
47 ampulla of vater neoplasm 10.7 IL6 OXT PGR
48 intermittent squint 10.7 GNRH1 PRL
49 drug rash with eosinophilia and systemic symptoms 10.7 CXCL8 IL6
50 capillary disease 10.7 CYP19A1 PGR PRL SHBG

Graphical network of the top 20 diseases related to Female Reproductive System Disease:



Diseases related to Female Reproductive System Disease

Symptoms & Phenotypes for Female Reproductive System Disease

UMLS symptoms related to Female Reproductive System Disease:


leukorrhea, mastodynia, genital itching, pruritus vulvae, vaginal pruritus, breast engorgement, nipple discharge, menometrorrhagia, perineal pain female, genitalia external painful, vaginal odor, menopausal symptoms, vaginal discomfort, vaginal pain, burning feeling vagina, mastoscirrhus, discomfort of vulva

MGI Mouse Phenotypes related to Female Reproductive System Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 10.2 AMH AREG BMP15 CYP19A1 FMR1 FOXL2
2 homeostasis/metabolism MP:0005376 10.07 AMH AREG CYP19A1 FOXL2 FSHR GDF9
3 digestive/alimentary MP:0005381 9.91 CYP19A1 GNRH1 IL6 OXT SERPINH1 TLR9
4 integument MP:0010771 9.85 FSHR GNRH1 IL6 OXT PGR PRL
5 neoplasm MP:0002006 9.5 AMH FSHR GNRH1 IL6 PGR PRL
6 reproductive system MP:0005389 9.5 FOXL2 FSHR GDF9 GNRH1 IL6 NOBOX

Drugs & Therapeutics for Female Reproductive System Disease

Drugs for Female Reproductive System Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 828)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Selenium Approved, Vet_approved Phase 4,Phase 3,Phase 2 7782-49-2
2
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 657-24-9 14219 4091
3
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-84-3 187
4
Desogestrel Approved Phase 4,Phase 3,Phase 2 54024-22-5 40973
5
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-28-2 5757
6
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 57-63-6 5991
7
Etonogestrel Approved, Investigational Phase 4,Phase 2,Phase 3 54048-10-1 40976 6917715
8
Methyltestosterone Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-18-4 6010
9
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-22-0 6013
10
Calcium Carbonate Approved Phase 4 471-34-1
11
Goserelin Approved Phase 4,Phase 3,Phase 2 65807-02-5 47725 5311128
12
Tibolone Approved Phase 4 5630-53-5
13
Ganirelix Approved Phase 4,Phase 3,Phase 2,Early Phase 1 123246-29-7, 124904-93-4 25081094
14
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 18323-44-9 29029
15
Cyproterone Acetate Approved, Investigational Phase 4,Phase 3,Phase 2 427-51-0
16
Leuprolide Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 53714-56-0 3911 657181
17
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-02-2 5743
18
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 57-83-0 5994
19
Drospirenone Approved Phase 4,Phase 3,Phase 1,Early Phase 1 67392-87-4 68873
20
Acetylcysteine Approved, Investigational Phase 4,Phase 3,Phase 1 616-91-1 12035
21
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 443-48-1 4173
22
Levonorgestrel Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 797-63-7, 17489-40-6 13109
23
Medroxyprogesterone acetate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 71-58-9
24
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
25
Cetrorelix Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 120287-85-6 16129715 25074887
26
Menotropins Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 61489-71-2, 9002-68-0 5360545
27
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 112809-51-5 3902
28
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
29
Heparin Approved, Investigational Phase 4,Phase 2,Phase 3 9005-49-6 772 46507594
30
Hydroxocobalamin Approved Phase 4 13422-51-0 11953898 5460373 44475014
31
Mefenamic acid Approved Phase 4,Phase 2,Phase 3 61-68-7 4044
32
Buserelin Approved Phase 4,Phase 3 57982-77-1
33
Menthol Approved Phase 4,Phase 3 2216-51-5 16666
34
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 137-58-6 3676
35
Tamoxifen Approved Phase 4,Phase 3,Phase 2 10540-29-1 2733526
36
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741 24759
37
Lenograstim Approved Phase 4,Phase 3,Phase 2,Phase 1 135968-09-1
38
Zinc Approved Phase 4,Phase 2,Phase 1,Early Phase 1 7440-66-6 32051 23994
39
Praziquantel Approved, Vet_approved Phase 4 55268-74-1 4891
40
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
41
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
42
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983
43
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
44
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
45
Anastrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 120511-73-1 2187
46
Desflurane Approved Phase 4 57041-67-5 42113
47
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
48
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
49
Benzocaine Approved Phase 4,Phase 3,Phase 2 1994-09-7, 94-09-7 2337
50
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943

Interventional clinical trials:

(show top 50) (show all 2712)

id Name Status NCT ID Phase Drugs
1 National,Multicentric Randomised Study of the Correction of Genital Prolapse With Fascial Repair or Mesh-Prolift Unknown status NCT00771225 Phase 4
2 Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism Unknown status NCT02140515 Phase 4 Lutropin alfa;Follitropin alfa and Lutropin alfa
3 Compare Sacrospinous Fixation Versus High Uterosacral Ligament Fixation for Uterus Vaginal Prolapse III/IV Unknown status NCT01347021 Phase 4
4 Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China Unknown status NCT01021904 Phase 4
5 Selenium Supplementation in Pregnancy Unknown status NCT01465867 Phase 4
6 Metformin for the Treatment of Unexplained Oligozspermia Unknown status NCT01529177 Phase 4 Metformin / clomid / hCG;Clomiphene citrate / hCG
7 Myoinositol for the Treatment of Ovarian and Psychiatric Disorder in Polycystic Ovary Syndrome (PCOS) Patients Unknown status NCT01246310 Phase 4
8 Assessment of the Effectiveness of a Program of Preparation to Pregnancy and Delivery Unknown status NCT01155804 Phase 4
9 Long Acting FSH Plus Antagonist Versus Daily FSH Plus Antagonist Versus Short Agonist Protocol in Poor Responders Undergoing IVF Unknown status NCT02070198 Phase 4 Long acting FSH and GnRH antagonist;Daily FSH and GnRH antagonist;Triptorelin and recombinant FSH
10 Botox on Vulvar Vestibulitis Unknown status NCT00119886 Phase 4 Botulinum toxin
11 IUI vs. IVF/ICSI in Women Aged 38-42 Years: a Prospective Randomized Controlled Trial. Unknown status NCT01992731 Phase 4
12 Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers Unknown status NCT01448291 Phase 4 Etonogestrel /Ethinyl Estradiol Contraceptive Vaginal Ring
13 Intrauterine Injection of Human Chorionic Gonadotropin Before Embryo Transfer in Women With Previous IVF Failure Unknown status NCT02329197 Phase 4 Human Chorionic Gonadotropin (HCG)
14 Functional Outcome After Groin Hernia Mesh Repair: Open Versus Laparoscopy Unknown status NCT00625534 Phase 4
15 Efficacy and Safety of Pulsatile Gonadotropin Releasing Hormone Pump Treatment in Patients With Idiopathic Hypogonadotropic Hypogonadism Unknown status NCT02310074 Phase 4 Pulsatile Gonadotropin Releasing Hormone;Human chorionic gonadotropin;Urinary Follicle-Stimulating Hormone
16 Testosterone Patch's Effects on the Cardiovascular System and Libido Unknown status NCT01208038 Phase 4 Intrinsa Transdermal testosterone patch
17 Use of Corifolitropin Alfa in Oocyte Donors Unknown status NCT02213627 Phase 4 Corifollitropin alfa;Recombinant FSH;HP-hMG
18 The Effect of LH-Priming During Early Follicular Phase in IVF Treatment. Unknown status NCT00334425 Phase 4 MENOPUR; GONAL-F
19 Randomized Study of Gonadotropin-releasing-hormone Agonist (GnRH-a) or Expectant Management for Endometriosis Unknown status NCT00654524 Phase 4 gonadotropin-releasing-hormone agonist (GnRHa) - Goserelin
20 Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls? Unknown status NCT01101750 Phase 4
21 Comparative Validation of the Triptorelin Test for the Diagnosis of CPP in Girls Unknown status NCT01278290 Phase 4 Triptorelin acetate and Gonadorelin acetate;Gonadorelin acetate and Triptorelin acetate
22 Probiotics Capsule as Supplemental Therapy for Group B Streptococci Infection and Vaginitis During Pregnancy Unknown status NCT01779193 Phase 4
23 Type of Gonadotropin and Embryo Kinetics of Development Unknown status NCT02402192 Phase 4 Corifollitropin alfa
24 CavatermTM vs TCRE in Women With DUB Unknown status NCT00549159 Phase 4
25 Physical Activity and ARTs Unknown status NCT01892111 Phase 4
26 Ovarian Stimulation: Inositol and Melatonin Unknown status NCT01267604 Phase 4 Recombinant FSH (rFSH)
27 Metformin in Step-down Regimen Versus Conventional Low Dose Step-up Protocol in Patients With PCOS Undergoing IVF Unknown status NCT01438190 Phase 4 Metformin, gonadotropins in step-down regimen;Placebo, gonadotropins in step-up regimen
28 Probiotic Versus Placebo as Adjuvant for Bacterial Vaginosis Treatment During Pregnancy Unknown status NCT01558388 Phase 4 Lactobacillus acidophilus;Placebo
29 the Effect of Diane-35 Pretreatment on In-vitro Fertilization Outcome for Patients With Polycystic Ovary Syndrome Unknown status NCT01752270 Phase 4 Diane-35 pretreatment;Diane-35 pretreatment
30 Study of Dual Trigger Ovulation in Oocyte Donors Unknown status NCT01443546 Phase 4 HCG;Lupron Trigger;Dual Trigger
31 Ovulation Induction With Clomiphene Citrate and Dexamethasone Unknown status NCT01856062 Phase 4 Placebo;Dexamethasone
32 Comparison of the Long GnRH Agonist Protocol and the Flexible GnRH Antagonist Protocol of Ovarian Stimulation Unknown status NCT00417183 Phase 4 Arvekap 0.1 mg (Triptorelin, Ipsen, France);Ganirelix 0.25 (Orgalutran, Organon, The Netherlands)
33 Comparison Between Natural and Artificial Cycle in Recipient Oocyte Patients Unknown status NCT01353846 Phase 4 Agonist GnRH; estradiol Valerate; progesterone
34 Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants Unknown status NCT02027337 Phase 4 20 mcg ethinylestradiol /3 mg drospirenone;20 mcg ethinylestradiol/3 mg drospirenone and Selmevit;30 mcg ethinylestradiol/3 mg drospirenone;30 mcg ethinylestradiol/3 mg drospirenone and Selmevit;35 mcg ethinylestradiol/2 mg cyproterone;35 mcg ethinylestradiol/2 mg cyproterone and Selmevit
35 Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis Unknown status NCT01841411 Phase 4 N-Acetyl cysteine;Metronidazole + N-Acetyl cysteine;metronidazole
36 A Randomized Controlled Trial of Acyclovir Among HIV and HSV-2 Co-Infected Women, Chiang Rai, Thailand Completed NCT00362596 Phase 4 acyclovir
37 Effectiveness, Safety and Immunogenicity of GSK Biologicals' HPV Vaccine GSK580299 (Cervarix TM) Administered in Healthy Adolescents Completed NCT00534638 Phase 4
38 Effect of Schistosomiasis Mansoni on HIV Susceptibility and Female Genital Immunology Completed NCT02878564 Phase 4 Praziquantel
39 Clinical Assessment of the Total Vaginal Mesh Technique for Treatment of Genital Prolapse Completed NCT00196495 Phase 4
40 Role of Intrauterine Cornual Block in Combination With Direct Cervical Block in Outpatient Endometrial Ablation Completed NCT01808898 Phase 4
41 Alternate Dosing Schedules Study for HPV Vaccine Completed NCT00862810 Phase 4
42 Alternate Dosing Schedules Study for HPV Vaccine (ADS) Completed NCT02280642 Phase 4
43 Predictors of Postoperative Pain Following Oocyte Retrieval for Assisted Reproduction Completed NCT03105518 Phase 4 Fentanyl;Acetaminophen;Oxycodone
44 Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease Completed NCT01034358 Phase 4
45 Anastrazole Plus GnRH-agonist in the Treatment of Endometriosis Recurrence Completed NCT01769781 Phase 4 anastrazole;GnRH analog alone
46 Effectiveness of Levonorgestrel-intrauterine System (LNG-IUS) Versus Depot Medroxyprogesterone Acetate (DMPA) in Treatment of Pelvic Pain in Clinically Diagnosed Endometriotic Patients Completed NCT02534688 Phase 4 LNG-IUS;DMPA
47 Recovery Following Desflurane Versus Sevoflurane for Outpatient Urologic Surgery in Elderly Females Completed NCT01310582 Phase 4 Desflurane;Sevoflurane
48 Sevoflurane, Propofol, Postoperative Pain Completed NCT01437462 Phase 4 Sevoflurane;Propofol
49 The Effects of Vitamin D on Transforming Growth Factor-beta1 in Polycystic Ovary Syndrome Completed NCT02460380 Phase 4 Vitamin D3
50 Evaluation of Physiologic and Standard Sex Steroid Replacement Regimens in Women With Premature Ovarian Failure Completed NCT00732693 Phase 4 Ethinylestradiol / Norethisterone;Estradiol / Progesterone

Search NIH Clinical Center for Female Reproductive System Disease

Cochrane evidence based reviews: genital diseases, female

Genetic Tests for Female Reproductive System Disease

Anatomical Context for Female Reproductive System Disease

MalaCards organs/tissues related to Female Reproductive System Disease:

39
Ovary, Testes, Uterus, Breast, Cervix, Prostate, Brain

Publications for Female Reproductive System Disease

Variations for Female Reproductive System Disease

Expression for Female Reproductive System Disease

Search GEO for disease gene expression data for Female Reproductive System Disease.

Pathways for Female Reproductive System Disease

Pathways related to Female Reproductive System Disease according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.34 AREG GDF9 GNRH1 IL6 TLR9
2 11.46 CXCL8 IL6 PRL
3 11.12 CXCL8 IL6 TLR9
4 10.96 BMP15 CYP19A1 FSHR GDF9
5 10.76 AREG CYP19A1 FSHR
6 10.53 CYP19A1 FSHR GDF9 PGR ZP3
7 10.52 FSHR GNRH1

GO Terms for Female Reproductive System Disease

Cellular components related to Female Reproductive System Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 AMH BMP15 CXCL8 GDF9 GNRH1 IL6
2 extracellular space GO:0005615 9.36 AMH AREG BMP15 CXCL8 GDF9 GNRH1

Biological processes related to Female Reproductive System Disease according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 female pregnancy GO:0007565 9.72 GNRH1 OXT PRL
2 BMP signaling pathway GO:0030509 9.71 AMH BMP15 GDF9
3 response to glucocorticoid GO:0051384 9.65 AREG IL6 OXT
4 regulation of MAPK cascade GO:0043408 9.61 BMP15 FSHR GDF9
5 ovarian follicle development GO:0001541 9.58 BMP15 FOXL2 NOBOX
6 response to molecule of bacterial origin GO:0002237 9.52 CXCL8 TLR9
7 gonad development GO:0008406 9.51 AMH FSHR
8 female gonad development GO:0008585 9.5 CYP19A1 FOXL2 FSHR
9 negative regulation of bone resorption GO:0045779 9.49 FSHR IL6
10 response to prostaglandin E GO:0034695 9.46 GNRH1 OXT
11 female gamete generation GO:0007292 9.43 BMP15 FSHR GDF9
12 oocyte growth GO:0001555 9.37 FOXL2 GDF9
13 uterus development GO:0060065 9.33 CYP19A1 FOXL2 FSHR
14 response to peptide hormone GO:0043434 9.26 AREG GNRH1 OXT TRPV1
15 response to organic cyclic compound GO:0014070 9.02 AMH AREG GNRH1 IL6 OXT

Molecular functions related to Female Reproductive System Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.46 AMH GNRH1 OXT PRL
2 transforming growth factor beta receptor binding GO:0005160 9.43 AMH BMP15 GDF9
3 cytokine activity GO:0005125 9.35 AREG BMP15 CXCL8 GDF9 IL6
4 siRNA binding GO:0035197 9.32 FMR1 TLR9
5 growth factor activity GO:0008083 9.02 AMH AREG BMP15 GDF9 IL6

Sources for Female Reproductive System Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....