MCID: FMR003
MIFTS: 37

Femoral Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Femoral Neuropathy

MalaCards integrated aliases for Femoral Neuropathy:

Name: Femoral Neuropathy 12 42 14 69
Femoral Nerve Dysfunction 12
Femoral Nerve Lesions 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4196
ICD10 33 G57.2 G57.20
MeSH 42 D020428
NCIt 47 C27595
SNOMED-CT 64 193146000 25690000
UMLS 69 C0751931

Summaries for Femoral Neuropathy

Disease Ontology : 12 A mononeuropathy that is characterized by a loss of movement or sensation in parts of the legs due to damage to the femoral nerve.

MalaCards based summary : Femoral Neuropathy, also known as femoral nerve dysfunction, is related to traumatic brain injury and neuropathy. An important gene associated with Femoral Neuropathy is VLDLR (Very Low Density Lipoprotein Receptor), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. The drugs Alprostadil and Heparin have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and brain.

Wikipedia : 72 The femoral nerve is a nerve in the thigh that supplies skin on the upper thigh and inner leg, and the... more...

Related Diseases for Femoral Neuropathy

Diseases related to Femoral Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
id Related Disease Score Top Affiliating Genes
1 traumatic brain injury 29.7 CEACAM5 SMUG1
2 neuropathy 10.7
3 iliac vein thrombophlebitis 10.6 PLG VLDLR
4 sulfhemoglobinemia 10.6 F3 PLG
5 fragile x syndrome type 2 10.6 F2 F3
6 otospondylomegaepiphyseal dysplasia 10.6 F3 PLG
7 46,xy ovotesticular disorder of sex development 10.6 F2 F3
8 von willibrand disease, type 3 10.6 F2 F3
9 testicular gonadoblastoma 10.6 F2 F3
10 female breast cancer 10.5 F2 F3
11 haemonchiasis 10.5 F3 SMUG1
12 sporotrichosis 10.5 F2 F3
13 cervical adenoma malignum 10.5 F3 SMUG1
14 egg allergy 10.5 F2 PLG
15 chronic inflammatory demyelinating polyneuritis 10.5 F2 F3
16 syndactyly, mesoaxial synostotic, with phalangeal reduction 10.5 F2 PLG
17 lymphatic system cancer 10.5 F2 F3
18 littre gland carcinoma 10.5 F2 PLG
19 facioscapulohumeral muscular dystrophy 1 10.5 F2 F3
20 lethal congenital contracture syndrome 10.5 F2 F3
21 mobitz type ii atrioventricular block 10.5 F3 PLG
22 colonic l-cell glucagon-like peptide producing tumor 10.5 PLG SMUG1
23 hyperhomocysteinemia 10.5 CYP2B6 PLG
24 essential thrombocythemia 10.5 F2 F3
25 factor v deficiency 10.5 F2 F3
26 spinal cord lipoma 10.5 F2 F3
27 coccidioidomycosis 10.5 F2 PLG
28 cryptosporidiosis 10.5 F2 PLG
29 congenital syphilis 10.5 F2 F3
30 oral cavity carcinoma in situ 10.5 F2 SMUG1
31 central retinal artery occlusion 10.5 F2 F3
32 red color blindness 10.4 F2 F3
33 pancreatic cystadenocarcinoma 10.4 F2 SMUG1
34 thymus small cell carcinoma 10.4 F2 SMUG1
35 hyperphenylalaninemia 10.4 F2 F3
36 bone resorption disease 10.4 F2 TBXAS1
37 hepadnavirus infection 10.4 F2 F3
38 generalized anxiety disorder 10.4 CEACAM5 PLG
39 parasitic helminthiasis infectious disease 10.4 F3 PLG
40 inherited blood coagulation disease 10.4 F2 F3
41 microcephaly 8, primary, autosomal recessive 10.4 F2 F3
42 childhood central nervous system immature teratoma 10.4 RPL34 SMUG1
43 epiphora due to excess lacrimation 10.4 CEACAM5 F2
44 intestine carcinoma in situ 10.4 CEACAM5 SMUG1
45 ureter squamous cell carcinoma 10.4 CEACAM5 SMUG1
46 monieziasis 10.4 CEACAM5 SMUG1
47 lipid-cell variant infiltrating bladder urothelial carcinoma 10.4 CEACAM5 SMUG1
48 blepharoconjunctivitis 10.3 F2 F3
49 haemophilus meningitis 10.3 F3 PLG
50 familial periodic paralysis 10.3 CEACAM5 SMUG1

Graphical network of the top 20 diseases related to Femoral Neuropathy:



Diseases related to Femoral Neuropathy

Symptoms & Phenotypes for Femoral Neuropathy

Drugs & Therapeutics for Femoral Neuropathy

Drugs for Femoral Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Alprostadil Approved, Investigational Phase 2 745-65-3 149351
2
Heparin Approved, Investigational Phase 2 9005-49-6 772 46507594
3
Iloprost Approved, Investigational Phase 2 78919-13-8 6443959
4 Anesthetics Phase 2,Phase 1
5 calcium heparin Phase 2
6 Pharmaceutical Solutions Phase 2
7 Platelet Aggregation Inhibitors Phase 2
8 Vasodilator Agents Phase 2
9 Calamus Nutraceutical Phase 2
10 Anesthetics, Local Phase 1
11
Ibuprofen Approved 15687-27-1 3672
12
Morphine Approved, Investigational 57-27-2 5288826
13
Ropivacaine Approved 84057-95-4 71273 175805
14 Analgesics
15 Analgesics, Opioid
16 Central Nervous System Depressants
17 Narcotics
18 Peripheral Nervous System Agents

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 The Therapeutical Role of Continuous Intra-femoral Artery Infusion of Urokinase on Diabetic Foot Ulcers Unknown status NCT01108120 Phase 2 continuous intra-femoral thrombolysis group;Conventional therapy group
2 The Arterial Measurement of the Blood Flow Volume After Iloprost Stimulation Recruiting NCT01774058 Phase 2 Ilomedin
3 Local Anaesthetic Following Hernia Repair Terminated NCT00471692 Phase 1 Ropivicaine
4 Femoral Nerve Block: Anatomical Insertion Point - A Prospective Randomised Double-Blind Controlled Trial Unknown status NCT00732706
5 Femoral Neuropathy After Anterior Cruciate Ligament Reconstruction: Femoral Nerve Block vs Patient-controlled Analgesia (PCA) Completed NCT01321138
6 Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block Withdrawn NCT01334632

Search NIH Clinical Center for Femoral Neuropathy

Cochrane evidence based reviews: femoral neuropathy

Genetic Tests for Femoral Neuropathy

Anatomical Context for Femoral Neuropathy

MalaCards organs/tissues related to Femoral Neuropathy:

39
Skin, Bone, Brain, Kidney

Publications for Femoral Neuropathy

Articles related to Femoral Neuropathy:

(show top 50) (show all 182)
id Title Authors Year
1
Bilateral Femoral Neuropathy Following Psoas Muscle Hematomas Caused by Enoxaparin Therapy. ( 28848224 )
2017
2
Femoral Neuropathy Following Spontaneous Retroperitoneal Hemorrhage After Cardiac Surgery: A Case Report. ( 28079661 )
2017
3
A Case of Idiopathic Femoral Neuropathy With Subsequent Quadriceps Atrophy. ( 28221309 )
2017
4
Sports induced femoral neuropathy: Review of literature. ( 27841202 )
2016
5
Ischemic-reperfusion of unilateral external iliac artery in rat: A new model for vasculitic femoral neuropathy. ( 27288016 )
2016
6
Poster 269 A Rare Case of Femoral Neuropathy Following Anterolateral Total Hip Arthroplasty. ( 27673026 )
2016
7
Bilateral Femoral Neuropathy After Transurethral Lithotomy in the Lithotomy Position: Report of a Case. ( 27224440 )
2016
8
A Rare Case of Femoral Neuropathy Associated with Ilio-Psoas Bursitis After 10 Years of Total Hip Arthroplasty. ( 26312109 )
2015
9
A Rare Case of Femoral Neuropathy Associated with Ilio-Psoas Bursitis After 10 Years of Total Hip Arthroplasty. ( 26587059 )
2015
10
Bilateral Iatrogenic Femoral Neuropathy. ( 26256661 )
2015
11
Femoral neuropathy caused by hyperlordotic positioning. ( 24554248 )
2014
12
Conservative treatment of femoral neuropathy following retroperitoneal hemorrhage: a case report and review of literature. ( 24686104 )
2014
13
Femoral neuropathy: a rare complication of retroperitoneal hematoma caused by cesarean section. ( 22941351 )
2013
14
High-resolution 3-T MR neurography of femoral neuropathy. ( 22194473 )
2012
15
Femoral neuropathy following total hip arthroplasty: review and management guidelines. ( 22696981 )
2012
16
Large psoas haematoma and femoral neuropathy in a patient with type 2B von Willebrand's disease. ( 23005922 )
2012
17
Femoral Neuropathy due to Iliacus Muscle Hematoma in a Patient on Warfarin Therapy. ( 22396845 )
2012
18
Bilateral femoral neuropathy after massive toxic ingestion in a suicide attempt. ( 22367832 )
2012
19
Femoral neuropathy and meralgia paresthetica secondary to an iliacus hematoma. ( 22639754 )
2012
20
Femoral neuropathy after vaginal surgery: a complication of the lithotomy position. ( 21281008 )
2011
21
Lumbar plexopathy caused by metastatic tumor, which was mistaken for postoperative femoral neuropathy. ( 22220245 )
2011
22
Duloxetine contributing to a successful multimodal treatment program for peripheral femoral neuropathy and comorbid 'reactive depression' in an adolescent. ( 22184557 )
2011
23
Transient femoral neuropathy after knee ligament reconstruction and nerve stimulator-guided continuous femoral nerve block: a case series. ( 21831093 )
2011
24
Acute femoral neuropathy: a rare complication after renal transplantation. ( 21168704 )
2010
25
Iatrogenic femoral neuropathy: two cases and literature update. ( 21386773 )
2010
26
Postpartum femoral neuropathy following spontaneous vaginal delivery. ( 20143990 )
2010
27
Femoral neuropathy caused by compressive iliopsoas hydatid cyst: a case report and review of the literature. ( 20478731 )
2010
28
Acute femoral neuropathy following renal transplantation: a retrospective, multicenter study in China. ( 20620504 )
2010
29
Ultrasound-guided placement of a permanent percutaneous femoral nerve stimulator leads for the treatment of intractable femoral neuropathy. ( 19668289 )
2009
30
Case report: femoral neuropathy secondary to total hip arthroplasty wear debris. ( 19452234 )
2009
31
Transient femoral neuropathy after abdominoplasty. ( 18948773 )
2008
32
The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty. ( 19097010 )
2008
33
Non-operative management of femoral neuropathy secondary to a traumatic iliacus haematoma in an adolescent. ( 18827251 )
2008
34
Iliopsoas bursitis-associated femoral neuropathy exacerbated after internal fixation of an intertrochanteric hip fracture in rheumatoid arthritis: a case report. ( 18421416 )
2008
35
Compressive femoral neuropathy: a rare complication of anticoagulation. ( 17342281 )
2007
36
Femoral neuropathy in a patient with rheumatoid arthritis. ( 17963353 )
2007
37
Iatrogenic femoral neuropathy following pelvic surgery: a rare and often overlooked complication--four case reports and literature review. ( 17939268 )
2007
38
Femoral neuropathy following retroperitoneal hemorrhage: case series and review of the literature. ( 16741653 )
2006
39
Femoral neuropathy in a dog with iliopsoas muscle injury. ( 16472299 )
2006
40
Epidural analgesia masked the diagnosis of femoral neuropathy following renal transplantation. ( 17037007 )
2006
41
Bilateral femoral neuropathy associated with disseminated intravascular coagulopathy: a case report. ( 17042241 )
2006
42
Femoral neuropathy due to patellar dislocation in a theatrical and jazz dancer: a case report. ( 15954069 )
2005
43
Femoral neuropathy induced by a low-grade myofibroblastic sarcoma of the groin. ( 15981081 )
2005
44
Bilateral femoral neuropathy complicating rhabdomyolysis and acute renal failure. ( 19078767 )
2005
45
Femoral neuropathy after pelvic surgery. ( 15779491 )
2004
46
Transient femoral neuropathy after harvest of bone from the iliac crest. ( 15544891 )
2004
47
The role of knee immobilizers in cancer patients with femoral neuropathy. ( 14966718 )
2004
48
Psoas haematoma and femoral neuropathy associated with enoxaparin therapy. ( 12918901 )
2003
49
Femoral neuropathy and iliopsoas hematoma as a result of postpartum factor-VIII inhibitor syndrome. A case report. ( 12954844 )
2003
50
Acute femoral neuropathy secondary to an iliacus muscle hematoma. ( 12686414 )
2003

Variations for Femoral Neuropathy

Expression for Femoral Neuropathy

Search GEO for disease gene expression data for Femoral Neuropathy.

Pathways for Femoral Neuropathy

GO Terms for Femoral Neuropathy

Biological processes related to Femoral Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.43 F2 F3 PLG
2 fibrinolysis GO:0042730 9.16 F2 PLG
3 negative regulation of fibrinolysis GO:0051918 8.96 F2 PLG
4 hemostasis GO:0007599 8.8 F2 F3 PLG

Molecular functions related to Femoral Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 apolipoprotein binding GO:0034185 8.62 PLG VLDLR

Sources for Femoral Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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