MCID: FTL001
MIFTS: 53

Fetal Alcohol Syndrome malady

Categories: Fetal diseases, Rare diseases, Mental diseases, Neuronal diseases

Aliases & Classifications for Fetal Alcohol Syndrome

About this section
Sources:
11Disease Ontology, 13DISEASES, 52Orphanet, 48Novoseek, 66UMLS, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 28ICD10
See all MalaCards sources

Aliases & Descriptions for Fetal Alcohol Syndrome:

Name: Fetal Alcohol Syndrome 11 13 52 48 66
Fetal Alcohol Spectrum Disorders 52 66
Fetus or Newborn Affected by Alcohol Transmitted Via Placenta or Breast Milk 66
Alcohol Related Neurodevelopmental Disorder 66
Alcohol-Related Neurodevelopmental Disorder 52
Alcohol-Related Birth Defects 52
 
Alcohol Related Birth Defect 66
Arnd 52
Arbd 52
Fasd 52
Fas 52

Characteristics:

Orphanet epidemiological data:

52
fetal alcohol syndrome:
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe),1-9/100000 (Austria),1-9/100000 (Belgium),1-5/10000 (Germany),1-9/100000 (Hungary),1-9/100000 (Ireland),1-9/100000 (Italy),1-9/100000 (Norway),1-5/10000 (Switzerland),1-9/100000 (United Kingdom),1-5/10000 (France),1-9/1000000 (Poland),1-9/100000 (Spain),6-9/10000 (Ukraine); Age of onset: Antenatal,Neonatal; Age of death: any age

Classifications:



External Ids:

Disease Ontology11 DOID:0050665
Orphanet52 ORPHA1915
ICD10 via Orphanet29 Q86.0
MESH via Orphanet38 D005310
UMLS via Orphanet67 C0015923
ICD1028 Q86.0

Summaries for Fetal Alcohol Syndrome

About this section
Disease Ontology:11 A fetal alcohol spectrum disorder that results in severe mental and physical defects which can develop in a child when the mother drinks alcohol during pregnancy. the presenting features include craniofacial dysmorphology (microcephaly, smooth philtrum, thin upper lip, small eye openings), pre- and postnatal growth deficiency, and central nervous system dysfunction.

MalaCards based summary: Fetal Alcohol Syndrome, also known as fetal alcohol spectrum disorders, is related to alcohol-related neurodevelopmental disorder and partial fetal alcohol syndrome, and has symptoms including microcephaly, narrow face and telecanthus. An important gene associated with Fetal Alcohol Syndrome is ADH1B (Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide), and among its related pathways are noradrenaline and adrenaline degradation and ethanol degradation II. Affiliated tissues include eye, breast and placenta, and related mouse phenotypes are vision/eye and homeostasis/metabolism.

Related Diseases for Fetal Alcohol Syndrome

About this section

Diseases in the Fetal Alcohol Syndrome family:

Fetal Alcohol Spectrum Disorder

Diseases related to Fetal Alcohol Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 120)
idRelated DiseaseScoreTop Affiliating Genes
1alcohol-related neurodevelopmental disorder23.0ADH1A, ADH1B, ADH7, ADNP, ALDH2, CHRM3
2partial fetal alcohol syndrome12.4
3fas-related autoimmune lymphoproliferative syndrome12.2
4autoimmune lymphoproliferative syndrome12.1
5fetal alcohol spectrum disorder11.8
6fanconi anemia, complementation group a11.7
7colorectal cancer11.6
8dianzani autoimmune lymphoproliferative disease11.5
9lung cancer11.5
10friedreich ataxia11.5
11obesity11.4
12pancreatic cancer11.4
13hepatocellular carcinoma11.4
14alcohol-related birth defect11.4
15prostate cancer11.4
16liver disease11.3
17hodgkin lymphoma11.3
18systemic lupus erythematosus11.3
19renal cell carcinoma11.3
20silicosis11.3
21myelodysplastic syndrome11.3
22viral hepatitis11.3
23adult t-cell leukemia11.3
24aplastic anemia11.3
25burkitt lymphoma11.3
26lymphopenia11.3
27asthma11.3
28pneumoconiosis11.3
29alzheimer disease11.2
30relapsing-remitting multiple sclerosis11.2
31hashimoto thyroiditis11.2
32cartilage-hair hypoplasia11.2
33thrombocytopenia11.2
34chronic lymphocytic leukemia11.2
35malignant glioma11.2
36common variable immunodeficiency11.2
37persistent polyclonal b-cell lymphocytosis11.2
38burn scar11.2
39acute myocarditis11.2
40stevens-johnson syndrome/toxic epidermal necrolysis11.2
41type ii mixed cryoglobulinemia11.2
42thyroid lymphoma11.2
43nodular goiter11.2
44fatty liver disease11.2
45acid sphingomyelinase deficiency11.2
46anoxia11.2
47cytomegalovirus infection11.2
48epstein-barr virus-associated gastric carcinoma11.2
49vogt-koyanagi-harada disease11.0
50lymphoma, non-hodgkin11.0

Graphical network of the top 20 diseases related to Fetal Alcohol Syndrome:



Diseases related to fetal alcohol syndrome

Symptoms for Fetal Alcohol Syndrome

About this section

Symptoms:

 52 (show all 32)
  • cleft palate
  • thin upper lip vermilion
  • microcephaly
  • narrow face
  • epicanthus
  • smooth philtrum
  • micrognathia
  • low-set, posteriorly rotated ears
  • anteverted nares
  • strabismus
  • telecanthus
  • ptosis
  • microphthalmos
  • microdontia
  • behavioral abnormality
  • congenital diaphragmatic hernia
  • intellectual disability
  • global developmental delay
  • specific learning disability
  • joint stiffness
  • intrauterine growth retardation
  • defect in the atrial septum
  • generalized hirsutism
  • short nose
  • vertebral segmentation defect
  • short stature
  • biparietal narrowing
  • abnormal dermatoglyphics
  • abnormality of immune system physiology
  • non-midline cleft lip
  • cognitive impairment
  • visceral angiomatosis

HPO human phenotypes related to Fetal Alcohol Syndrome:

(show all 29)
id Description Frequency HPO Source Accession
1 microcephaly hallmark (90%) HP:0000252
2 narrow face hallmark (90%) HP:0000275
3 telecanthus hallmark (90%) HP:0000506
4 behavioral abnormality hallmark (90%) HP:0000708
5 intrauterine growth retardation hallmark (90%) HP:0001511
6 short stature hallmark (90%) HP:0004322
7 cognitive impairment hallmark (90%) HP:0100543
8 thin vermilion border typical (50%) HP:0000233
9 epicanthus typical (50%) HP:0000286
10 abnormality of the philtrum typical (50%) HP:0000288
11 narrow forehead typical (50%) HP:0000341
12 micrognathia typical (50%) HP:0000347
13 low-set, posteriorly rotated ears typical (50%) HP:0000368
14 anteverted nares typical (50%) HP:0000463
15 strabismus typical (50%) HP:0000486
16 ptosis typical (50%) HP:0000508
17 microdontia typical (50%) HP:0000691
18 limitation of joint mobility typical (50%) HP:0001376
19 atria septal defect typical (50%) HP:0001631
20 short nose typical (50%) HP:0003196
21 vertebral segmentation defect typical (50%) HP:0003422
22 abnormal dermatoglyphics typical (50%) HP:0007477
23 aplasia/hypoplasia affecting the eye typical (50%) HP:0008056
24 abnormality of immune system physiology typical (50%) HP:0010978
25 non-midline cleft lip typical (50%) HP:0100335
26 visceral angiomatosis typical (50%) HP:0100761
27 cleft palate occasional (7.5%) HP:0000175
28 congenital diaphragmatic hernia occasional (7.5%) HP:0000776
29 hypertrichosis occasional (7.5%) HP:0000998

Drugs & Therapeutics for Fetal Alcohol Syndrome

About this section

Drugs for Fetal Alcohol Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
EthanolPhase 3, Phase 2, Phase 1, Phase 0197164-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
2
Epigallocatechin gallatePhase 2, Phase 358989-51-565064
Synonyms:
(-)-Epigallocatechin gallat
(-)-Epigallocatechin gallate
(-)-Epigallocatechin-3-O-gallate
(-)-Epigallocatechol gallate
(-)-Epigallocatehin gallate
Catechin deriv.
 
EGCG
Epigallocatcchin Gallate
Epigallocate
Epigallocatechin 3-gallate
Epigallocatechin Gallate
Epigallocic acid
Galloyl-L-epigallocatechol
Tea catechin
3
EpigallocatechinNutraceuticalPhase 2, Phase 359970-74-172277
Synonyms:
(-)-3,3',4',5,5',7-Flavanhexol
(-)-Epigallocatechol
(-)-cis-3,3',4',5,5',7-Hexahydroxyflavan
(-)-cis-3,3',4',5,5',7-Hexahydroxyflavane
(-)-epi-gallocatechin
(-)-epigallocatechin
(-)-epigallocatechol
(−)-epigallocatechin
2,3-cis-Epigallocatechin
 
3,3',4',5,5',7-flavanhexol
Antiscurvy factor C2
EGC
Epi-gallocatechin
Epigallocatechin
Epigallocatechol
Galloepicatechin
L-Epigallocatechin
L-Epigallocatechol
L-epigallocatechin
4
GlycerolPhase 221056-81-5753
Synonyms:
1,2,3-Trihydroxypropane
1,2,3-propanetriol
1,2,3-trihydroxypropane
Bulbold
Cristal
E 422
Emery 916
Glyceol Opthalgan
Glycerin
Glycerin,anhydrous
Glycerine
Glycerinum
Glyceritol
 
Glycerol
Glycerol 85%
Glycyl alcohol
Glyrol
Glysanin
IFP
Incorporation factor
Mackstat H 66
Monoctanoin component D
Osmoglyn
Pricerine 9091
Propanetriol
RG-S
Trihydroxypropane
Tryhydroxypropane
5
CholineNutraceuticalPhase 2, Phase 114762-49-7305
Synonyms:
(2-Hydroxyethyl)trimethyl ammonium
(2-Hydroxyethyl)trimethylammonium
(beta-hydroxyethyl)trimethylammonium
2-Hydroxy-N,N,N-trimethyl-ethanaminium
2-Hydroxy-N,N,N-trimethylethanaminium
Bilineurine
Biocolina
Biocoline
Choline
Choline cation
 
Choline ion
Cholinum
Hepacholine
Hormocline
Lipotril
N,N,N-Trimethylethanol-ammonium
N,N,N-Trimethylethanolammonium
N,N,N-trimethylethanol-ammonium
N-trimethylethanolamine
Neocolina
Paresan
trimethylethanolamine
6
Nicotine101654-11-5942, 89594
Synonyms:
(−
(+)-Nicotine
(+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine
(+-)-Nicotine
(-)-3-(1-Methyl-2-pyrrolidyl)pyridine
(-)-3-(N-Methylpyrrolidino)pyridine
(-)-Nicotine
(-)-Nicotine solution
(2S) 3-(1-Methyl-pyrrolidin-2-yl)-pyridine
(R)-3-(1-Methyl-2-pyrrolidinyl)pyridine
(R,S)-Nicotine
(R,S)-nicotine
(RS)-nicotine
(S)-(-)-NICOTINE, 3-[(2S)-1-METHYL-2-PYRROLIDINYL] PYRIDINE
(S)-(-)-Nicotine
(S)-3-(1-methylpyrrolidin-2-yl)pyridine
(S)-3-(N-methylpyrrolidin-2-yl)pyridine
(S)-Nicotine
(±)-nicotine
)-1-Methyl-2-(3-pyridyl)pyrrolidine
)-Nicotine
)-Nicotine solution
1-Methyl-2-(3-pyridal)-Pyrrolidine
1-Methyl-2-(3-pyridal)-pyrrolidene
1-Methyl-2-(3-pyridiyl)pyrrolidine
1-Methyl-2-(3-pyridyl)pyrrolidine
1uw6
2'-beta-H-Nicotine
3-(1-Methyl-2-pyrollidinyl)pyridine
3-(1-Methyl-2-pyrrolidinyl)-Pyridine
3-(1-Methyl-2-pyrrolidinyl)pyridine
3-(1-Methylpyrrolidin-2-yl)pyridine
3-(2-(N-methylpyrrolidinyl))pyridine
3-(N-Methylpyrollidino)pyridine
3-(N-Methylpyrrolidino)pyridine
3-N-Methylpyrrolidine
3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
36733_FLUKA
36733_RIEDEL
434F7990-3240-4A43-ACEC-E6CC1E495FA0
46343_FLUKA
46343_RIEDEL
54-11-5
AC1L3I79
AC1Q3ZOC
AI3-03424
BB_NC-0777
BIDD:GT0599
BRD-K05395900-322-02-1
Black Leaf
Black Leaf 40
C00745
CCRIS 1637
CHEBI:17688
CHEMBL3
CID89594
CPD000059074
Campbell's Nico-Soap
Caswell No. 597
Commit
D-Nicotine
D03365
DL-tetrahydronicotyrine
Destruxol
Destruxol Orchid Spray
EINECS 200-193-3
ENT 3,424
EPA Pesticide Chemical Code 056702
Emo-Nik
Flux Maag
Fumeto bac
Fumetobac
HSDB 1107
Habitrol
Habitrol (TN)
L(-)-nicotine
L-3-(1-Methyl-2-pyrrolidyl)pyridine
 
L-Nicotine
LS-202
MLS001055457
MLS001335905
Mach-Nic
Methyl-2-pyrrolidinyl)pyridine
Micotine
MolPort-000-744-731
N3876_SIGMA
N5511_FLUKA
N5511_SIGMA
NCGC00090693-01
NCGC00090693-02
NCGC00090693-03
NCGC00090693-04
NCGC00090693-05
NCGC00090693-06
NCGC00090693-07
NCT
NICOTINE AND SALTS
NSC 5065
NSC97238
Niagara P.A. Dust
Nic-Sal
Nico-Dust
Nico-Fume
Nicocide
Nicoderm
Nicoderm Cq
Nicoderm Patch
Nicorette
Nicorette Plus
Nicotin
Nicotina
Nicotina [Italian]
Nicotine
Nicotine (USP)
Nicotine (compounds related to)
Nicotine Alkaloid
Nicotine Patch
Nicotine Polacrilex
Nicotine [BSI:ISO]
Nicotine [UN1654]
Nicotine [UN1654] [Poison]
Nicotine [USAN]
Nicotrol
Nicotrol Inhaler
Nicotrol Ns
Nictoine patch
Nikotin
Nikotin [German]
Nikotyna
Nikotyna [Polish]
Ortho N-4 Dust
Ortho N-5 Dust
PDSP1_000113
PDSP1_000465
PDSP2_000463
PDSP2_000555
Prostep
R)-(+)-Nicotine
RCRA waste no. P075
RCRA waste number P075
SAM002564224
SDCCGMLS-0066911.P001
SMR000059074
Tendust
Transdermal Nicotine
UN1654
a -N-Methylpyrrolidine
a-N-Methylpyrrolidine
alpha-N-Methylpyrrolidine
beta-Pyridyl-alpha-N-methyl pyrrolidine
beta-Pyridyl-alpha-N-methylpyrrolidine
bmse000105
delta-Nicotine
nicotine
nicotine replacement patch
7
Benzocaine17941994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
8tannic acidNutraceutical1794

Interventional clinical trials:

(show all 30)
idNameStatusNCT IDPhase
1Open-Label Study of the Long Term Tolerability and Safety of Atomoxetine in Children With FASD and ADD/ADHDRecruitingNCT00418262Phase 3
2Epigallocatechin Gallate (EGCG) to Improve Cognitive Performance in Foetal Alcohol Syndrome (FAS) ChildrenRecruitingNCT02558933Phase 2, Phase 3
3Assess the Effectiveness of Atomoxetine in Children With Fetal Alcohol Syndrome and ADD/ADHDActive, not recruitingNCT00417794Phase 3
4Choline Supplementation in Children With Fetal Alcohol Spectrum DisordersCompletedNCT01911299Phase 2
5Fetal Alcohol Syndrome/ARND Research ConsortionCompletedNCT00164554Phase 1, Phase 2
6Fetal Alcohol Syndrome: Socio-Cognitive HabilitationCompletedNCT00164229Phase 1, Phase 2
7Neurocognitive Habilitation for Children With Fetal Alcohol Syndrome (FAS)/Alcohol-Related Neurodevelopmental Disorder (ARND)CompletedNCT00164346Phase 1, Phase 2
8A Media Based Motivational Intervention to Prevent Alcohol Exposed Pregnancies (AEPs)CompletedNCT00219336Phase 2
9Postnatal Choline Supplementation in Children With Prenatal Alcohol ExposureCompletedNCT01149538Phase 1, Phase 2
10Project CHOICES Efficacy StudyCompletedNCT00153478Phase 2
11Neighborhood Alcohol & HIV Prevention in South African Townships (Philani)Active, not recruitingNCT00996528Phase 2
12Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum DisordersNot yet recruitingNCT02735473Phase 2
13Development of Education Materials for Prevention of FAS in RussiaCompletedNCT01971398
14Improving Self Regulation in Children With Fetal Alcohol Syndrome Spectrum Disorders: A Neuroplastic InterventionCompletedNCT02457676
15Evaluating the Effectiveness of an Attachment-Focused Intervention in Preschool Children With FASDCompletedNCT01536184
16Preventing FAS/ARND in Russian ChildrenCompletedNCT01961050
17Expansion to Interdisciplinary HIV Prevention in WomenCompletedNCT01994603
18Fetal Alcohol Damage Prevention StudyCompletedNCT00696085
19Healthy Moms Alcohol InterventionCompletedNCT00244062
20Effects of Hyperbaric Oxygen Therapy in Autistic Children: A Pilot StudyCompletedNCT00324909
21Reducing Alcohol Exposed Pregnancy Risk: EARLY Randomized Controlled TrialCompletedNCT01446653
22Comprehensive Program for Youth Mental HealthCompletedNCT02169960
23Parenting Training for Children With FASDRecruitingNCT02210455
24Contraception and Alcohol Risk Reduction Internet Intervention Randomized TrialRecruitingNCT02128880
25Prevention of Fetal Alcohol Spectrum Disorder (FASD) by the Use of TechnologyEnrolling by invitationNCT02759874
26Prenatal Alcohol Biomarker Study in UruguayNot yet recruitingNCT02600624
27Self-Regulation in Adolescents With FASD: The Efficacy of a Targeted InterventionNot yet recruitingNCT02912962
28Better Nights, Better Days for Children With Neurodevelopment DisordersNot yet recruitingNCT02694003
29Modeling and Testing Change in Mental Abilities in ChildhoodNot yet recruitingNCT02459873
30Evaluating the Efficacy of a Video Based Intervention to Educate Teen Moms About Fetal Alcohol Syndrome (FAS)TerminatedNCT00747630Phase 0

Search NIH Clinical Center for Fetal Alcohol Syndrome

Genetic Tests for Fetal Alcohol Syndrome

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Anatomical Context for Fetal Alcohol Syndrome

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MalaCards organs/tissues related to Fetal Alcohol Syndrome:

34
Eye, Breast, Placenta, Brain, Testes, Liver, Endothelial

Animal Models for Fetal Alcohol Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Fetal Alcohol Syndrome:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.1ALDH2, CHRM3, GFAP, PFAS, RBP1, SHH
2MP:00053766.9ADH7, ALDH2, CHRM3, GFAP, GRIN2B, KCNJ2
3MP:00053786.8ADH7, ALDH2, CHRM3, GFAP, GRIN2B, KCNJ2
4MP:00053866.7ADH7, ALDH2, CHRM3, GFAP, GRIN2A, GRIN2B
5MP:00036316.4ADH7, ADNP, ALDH2, CHRM3, GFAP, GRIN2A

Publications for Fetal Alcohol Syndrome

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Articles related to Fetal Alcohol Syndrome:

(show top 50)    (show all 535)
idTitleAuthorsYear
1
Fetal alcohol syndrome (FAS) and fetal alcohol spectrum disorder (FASD)-diagnosis and moral policing; an ethical dilemma for paediatricians. (25005521)
2014
2
Advances in the development of novel antioxidant therapies as an approach for fetal alcohol syndrome prevention. (25131946)
2014
3
The role of NADPH oxidase in a mouse model of fetal alcohol syndrome. (24334207)
2013
4
Health care burden and cost associated with fetal alcohol syndrome: based on official Canadian data. (22900084)
2012
5
The first description of fetal alcohol syndrome by French pediatrician Paul Lemoine. (22684432)
2012
6
The expression of antioxidant enzymes in a mouse model of fetal alcohol syndrome. (22365038)
2012
7
Drugs, alcohol, pregnancy, and the fetal alcohol syndrome. (21239909)
2011
8
Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome. (18366608)
2008
9
Impaired eyeblink conditioning in children with fetal alcohol syndrome. (18162064)
2008
10
Reprogramming of genetic networks during initiation of the Fetal Alcohol Syndrome. (17200951)
2007
11
Metabolic and genetic factors contributing to alcohol induced effects and fetal alcohol syndrome. (16908065)
2007
12
Using the past to step forward: fetal alcohol syndrome in the Western Cape Province of South Africa. (15983266)
2005
13
Fetal alcohol syndrome. Introduction. (15223535)
2004
14
Increased sibling mortality in children with fetal alcohol syndrome. (15223547)
2004
15
A comparison of fetal alcohol syndrome surveillance network and birth defects surveillance methodology in determining prevalence rates of fetal alcohol syndrome. (14703793)
2003
16
A public health program for preventing fetal alcohol syndrome among women at risk in Montana. (14624976)
2003
17
Children with Fetal Alcohol Syndrome are impaired at place learning but not cued-navigation in a virtual Morris water task. (12842299)
2003
18
From the Centers for Disease Control and Prevention. Fetal alcohol syndrome--Alaska, Arizona, Colorado, and New York, 1995-1997. (12099269)
2002
19
Fetal alcohol syndrome. (20046289)
2002
20
Midaortic syndrome associated with fetal alcohol syndrome. (12427818)
2002
21
A multiple source methodology for the surveillance of fetal alcohol syndrome--The Fetal Alcohol Syndrome Surveillance Network (FASSNet). (12239744)
2002
22
Prevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome. (11303069)
2001
23
Gin Lane: did Hogarth know about fetal alcohol syndrome? (11259209)
2001
24
Physician awareness and screening for fetal alcohol syndrome. (11010122)
2000
25
Epidemiology of fetal alcohol syndrome in a South African community in the Western Cape Province. (11111264)
2000
26
Incidence of fetal alcohol syndrome on the southern part of RAcunion Island (France) (10440770)
1999
27
Bone age and growth in fetal alcohol syndrome. (9756047)
1998
28
Hospital utilization of Saskatchewan people with fetal alcohol syndrome. (9813924)
1998
29
Fetal alcohol syndrome update. (9323398)
1997
30
Fetal alcohol syndrome. (9113456)
1997
31
Optic nerve hypoplasia in fetal alcohol syndrome: an update. (9352281)
1997
32
Blackcurrant seed oil, zinc, and fetal alcohol syndrome. (9270175)
1997
33
Auditory event-related potentials in fetal alcohol syndrome and Down's syndrome children. (8651459)
1996
34
Loss of myelinated axons is specific to the central nervous system in a mouse model of the fetal alcohol syndrome. (8586571)
1995
35
Computational modeling of a putative fetal alcohol syndrome mechanism. (8749832)
1995
36
Ethanol effects on embryonic craniofacial growth and development: implications for study of the fetal alcohol syndrome. (8198217)
1994
37
Correlates of psychopathology and intelligence in children with fetal alcohol syndrome. (8188802)
1994
38
Fetal alcohol syndrome: review of the literature with implications for physical therapists. (7689232)
1993
39
Fetal alcohol syndrome--United States, 1979-1992. (8479418)
1993
40
Corneal endothelial anomalies in the fetal alcohol syndrome. (1497528)
1992
41
Fetal alcohol syndrome: a case report of neuropsychological, MRI and EEG assessment of two children. (1443415)
1992
42
Fetal alcohol syndrome. (17777021)
1992
43
Fetal alcohol syndrome and fatty acid ethyl esters. (1603626)
1992
44
Fetal alcohol syndrome in adolescents and adults. (2008025)
1991
45
Fetal alcohol syndrome. (1920109)
1991
46
A revised estimate of the economic impact of fetal alcohol syndrome. (1758979)
1991
47
Ethanol consumption inhibits fetal DNA methylation in mice: implications for the fetal alcohol syndrome. (1877725)
1991
48
Fetal alcohol syndrome: a description of oral motor, articulatory, short-term memory, grammatical, and semantic abilities. (2341602)
1990
49
Fetal alcohol syndrome: report of one case. (2260467)
1990
50
A cephalometric assessment of children with fetal alcohol syndrome. (2705412)
1989

Variations for Fetal Alcohol Syndrome

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Expression for genes affiliated with Fetal Alcohol Syndrome

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Search GEO for disease gene expression data for Fetal Alcohol Syndrome.

Pathways for genes affiliated with Fetal Alcohol Syndrome

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Pathways related to Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
10.0ADH1B, ALDH2
2
Show member pathways
10.0ADH1B, ALDH2
3
Show member pathways
9.7ADH1A, ADH1B
49.4GRIN2A, GRIN2B
59.4GRIN2A, GRIN2B
69.4GRIN2A, GRIN2B
79.4GRIN2A, GRIN2B
89.4GRIN2A, GRIN2B
9
Show member pathways
9.3ADH1A, ADH1B, ADH7
10
Show member pathways
9.0ADH1A, ADH1B, ADH7, ALDH2
11
Show member pathways
9.0ADH1A, ADH1B, ADH7, ALDH2
12
Show member pathways
9.0ADH1A, ADH1B, ADH7, ALDH2
13
Show member pathways
9.0ADH1A, ADH1B, ADH7, ALDH2
14
Show member pathways
9.0ADH1A, ADH1B, ADH7, ALDH2

GO Terms for genes affiliated with Fetal Alcohol Syndrome

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Cellular components related to Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1NMDA selective glutamate receptor complexGO:00171469.9GRIN2A, GRIN2B
2postsynaptic membraneGO:00452119.1CHRM3, GRIN2A, GRIN2B

Biological processes related to Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1ethanol catabolic processGO:000606810.3ADH7, ALDH2
2glutamate receptor signaling pathwayGO:000721510.0GRIN2A, GRIN2B
3regulation of sensory perception of painGO:005193010.0GRIN2A, VIP
4alcohol metabolic processGO:000606610.0ADH1A, ALDH2
5retinoic acid metabolic processGO:00425739.9ADH7, RBP1
6Bergmann glial cell differentiationGO:00600209.9GFAP, SHH
7retinol metabolic processGO:00425729.8ADH7, RBP1
8ionotropic glutamate receptor signaling pathwayGO:00352359.8GRIN2A, GRIN2B
9long-term synaptic potentiationGO:00602919.6GFAP, GRIN2A
10ethanol oxidationGO:00060699.6ADH1A, ADH1B, ADH7, ALDH2
11intermediate filament organizationGO:00451099.5GFAP, SHH
12negative regulation of protein catabolic processGO:00421779.4GRIN2A, SHH
13learning or memoryGO:00076119.2GRIN2A, GRIN2B, VIP
14response to ethanolGO:00454718.7ADH7, GRIN2A, GRIN2B

Molecular functions related to Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1extracellular-glutamate-gated ion channel activityGO:000523410.1GRIN2A, GRIN2B
2NMDA glutamate receptor activityGO:000497210.1GRIN2A, GRIN2B
3retinol bindingGO:001984110.1ADH7, RBP1
4alcohol dehydrogenase activity, zinc-dependentGO:000402410.0ADH1A, ADH1B, ADH7
5retinol dehydrogenase activityGO:00047459.8ADH1A, ADH7
6alcohol dehydrogenase (NAD) activityGO:00040229.8ADH1A, ADH7
7zinc ion bindingGO:00082707.4ADH1A, ADH1B, ADH7, GRIN2A, GRIN2B, SHH

Sources for Fetal Alcohol Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet