MCID: FTL001
MIFTS: 50

Fetal Alcohol Syndrome malady

Fetal diseases, Rare diseases, Neuronal diseases categories

Aliases & Classifications for Fetal Alcohol Syndrome

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Sources:
10Disease Ontology, 47Novoseek, 12DISEASES, 51Orphanet, 2CDC, 65UMLS, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 27ICD10
See all sources

Aliases & Descriptions for Fetal Alcohol Syndrome:

Name: Fetal Alcohol Syndrome 10 47 12 51 2 65
Fetal Alcohol Spectrum Disorders 51 65
Fetus or Newborn Affected by Alcohol Transmitted Via Placenta or Breast Milk 65
Alcohol-Related Neurodevelopmental Disorder 51
Alcohol Related Neurodevelopmental Disorder 65
Alcohol-Related Birth Defects 51
 
Alcohol Related Birth Defect 65
Arnd 51
Arbd 51
Fasd 51
Fas 51


Classifications:



Characteristics (Orphanet epidemiological data):

51
fetal alcohol syndrome:
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe),1-9/100000 (Austria),1-9/100000 (Belgium),1-5/10000 (Germany),1-9/100000 (Hungary),1-9/100000 (Ireland),1-9/100000 (Italy),1-9/100000 (Norway),1-5/10000 (Switzerland),1-9/100000 (United Kingdom),1-5/10000 (France),1-9/1000000 (Poland),1-9/100000 (Spain),6-9/10000 (Ukraine); Age of onset: Antenatal,Neonatal; Age of death: any age


External Ids:

Disease Ontology10 DOID:0050665
Orphanet51 1915
ICD10 via Orphanet28 Q86.0
MESH via Orphanet37 D005310
UMLS via Orphanet66 C0015923
ICD1027 Q86.0

Summaries for Fetal Alcohol Syndrome

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Disease Ontology:10 A fetal alcohol spectrum disorder that results in severe mental and physical defects which can develop in a child when the mother drinks alcohol during pregnancy. the presenting features include craniofacial dysmorphology (microcephaly, smooth philtrum, thin upper lip, small eye openings), pre- and postnatal growth deficiency, and central nervous system dysfunction.

MalaCards based summary: Fetal Alcohol Syndrome, also known as fetal alcohol spectrum disorders, is related to alcohol dependence and leukemia, and has symptoms including microcephaly, narrow face and telecanthus. An important gene associated with Fetal Alcohol Syndrome is ADH1B (Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide), and among its related pathways are noradrenaline and adrenaline degradation and ethanol degradation IV. Affiliated tissues include eye, breast and placenta, and related mouse phenotypes are vision/eye and behavior/neurological.

Related Diseases for Fetal Alcohol Syndrome

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Graphical network of the top 20 diseases related to Fetal Alcohol Syndrome:



Diseases related to fetal alcohol syndrome

Symptoms for Fetal Alcohol Syndrome

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Symptoms:

 51 (show all 31)
  • microcephaly
  • narrow face
  • telecanthus/canthal dystopy
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • psychic/behavioural troubles
  • short stature/dwarfism/nanism
  • intrauterine growth retardation
  • antenatal exposure : alcohol
  • narrow forehead
  • micrognathia/retrognathia/micrognathism/retrognathism
  • anophthalmos/anophthalmia/microphthalmos/microphthalmia
  • strabismus/squint
  • ptosis
  • epicanthic folds
  • short/small nose
  • anteverted nares/nostrils
  • thin/retracted lips
  • philtrum flat/large/featureless/absent cupidon bows
  • lateral cleft lip/gingival cleft/paramedian nasal cleft
  • complete/partial microdontia
  • low set ears/posteriorly rotated ears
  • vertebral segmentation anomaly/hemivertebrae
  • abnormal dermatoglyphics
  • atrial septal defect/interauricular communication
  • visceral angiomatosis (excluding skin)
  • restricted joint mobility/joint stiffness/ankylosis
  • immunodeficiency/increased susceptibility to infections/recurrent infections
  • cleft palate without cleft lip/submucosal cleft palate/bifid uvula
  • hirsutism/hypertrichosis/increased body hair
  • diaphragmatic hernia/defect/agenesis
  • stillbirth/neonatal death

HPO human phenotypes related to Fetal Alcohol Syndrome:

(show all 29)
id Description Frequency HPO Source Accession
1 microcephaly hallmark (90%) HP:0000252
2 narrow face hallmark (90%) HP:0000275
3 telecanthus hallmark (90%) HP:0000506
4 behavioral abnormality hallmark (90%) HP:0000708
5 intrauterine growth retardation hallmark (90%) HP:0001511
6 short stature hallmark (90%) HP:0004322
7 cognitive impairment hallmark (90%) HP:0100543
8 thin vermilion border typical (50%) HP:0000233
9 epicanthus typical (50%) HP:0000286
10 abnormality of the philtrum typical (50%) HP:0000288
11 narrow forehead typical (50%) HP:0000341
12 micrognathia typical (50%) HP:0000347
13 low-set, posteriorly rotated ears typical (50%) HP:0000368
14 anteverted nares typical (50%) HP:0000463
15 strabismus typical (50%) HP:0000486
16 ptosis typical (50%) HP:0000508
17 microdontia typical (50%) HP:0000691
18 limitation of joint mobility typical (50%) HP:0001376
19 atria septal defect typical (50%) HP:0001631
20 short nose typical (50%) HP:0003196
21 vertebral segmentation defect typical (50%) HP:0003422
22 abnormal dermatoglyphics typical (50%) HP:0007477
23 aplasia/hypoplasia affecting the eye typical (50%) HP:0008056
24 abnormality of immune system physiology typical (50%) HP:0010978
25 non-midline cleft lip typical (50%) HP:0100335
26 visceral angiomatosis typical (50%) HP:0100761
27 cleft palate occasional (7.5%) HP:0000175
28 congenital diaphragmatic hernia occasional (7.5%) HP:0000776
29 hypertrichosis occasional (7.5%) HP:0000998

Drugs & Therapeutics for Fetal Alcohol Syndrome

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Drugs for Fetal Alcohol Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AtomoxetineapprovedPhase 315982248-59-754841
Synonyms:
(-)-Tomoxetine
(3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine
83015-26-3
AC-5316
AC1L1HTI
AC1Q57N5
Atomoxetine
Atomoxetine (INN)
BRD-K20141153-003-03-8
CHEBI:127342
CHEMBL641
CID54841
D07473
DB00289
 
HSDB 7352
LS-187331
MolPort-002-052-062
NCGC00025345-01
PDSP1_000504
PDSP2_000502
Strattera
Tocris-2011
Tomoxetina
Tomoxetina [Spanish]
Tomoxetine
Tomoxetine [INN]
Tomoxetinum
Tomoxetinum [Latin]
UNII-ASW034S0B8
2Phase 3, Phase 2, Phase 1, Phase 0
3
Epigallocatechin gallatePhase 2, Phase 356989-51-565064
Synonyms:
(-)-Epigallocatechin gallat
(-)-Epigallocatechin gallate
(-)-Epigallocatechin-3-O-gallate
(-)-Epigallocatechol gallate
(-)-Epigallocatehin gallate
Catechin deriv.
 
EGCG
Epigallocatcchin Gallate
Epigallocate
Epigallocatechin 3-gallate
Epigallocatechin Gallate
Epigallocic acid
Galloyl-L-epigallocatechol
Tea catechin
4Epigallocatechinexperimental, NutraceuticalPhase 2, Phase 3509882981
5
Cholineapproved, nutraceuticalPhase 2, Phase 112262-49-7305
Synonyms:
(2-Hydroxyethyl)trimethyl ammonium
(2-Hydroxyethyl)trimethylammonium
(beta-hydroxyethyl)trimethylammonium
2-Hydroxy-N,N,N-trimethyl-ethanaminium
2-Hydroxy-N,N,N-trimethylethanaminium
Bilineurine
Biocolina
Biocoline
Choline
Choline cation
 
Choline ion
Cholinum
Hepacholine
Hormocline
Lipotril
N,N,N-Trimethylethanol-ammonium
N,N,N-Trimethylethanolammonium
N,N,N-trimethylethanol-ammonium
N-trimethylethanolamine
Neocolina
Paresan
trimethylethanolamine
6
GlycerolexperimentalPhase 217656-81-5753
Synonyms:
1,2,3-Trihydroxypropane
Bulbold
Cristal
E 422
Emery 916
Glyceol Opthalgan
Glycerin
Glycerine
Glyceritol
Glycerol
 
Glycyl alcohol
Glyrol
Glysanin
IFP
Incorporation factor
Mackstat H 66
Osmoglyn
Pricerine 9091
Propanetriol
RG-S
Trihydroxypropane
Tryhydroxypropane
7
Nicotineapproved92354-11-5942, 89594
Synonyms:
(−
(+)-Nicotine
(+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine
(+-)-Nicotine
(-)-3-(1-Methyl-2-pyrrolidyl)pyridine
(-)-3-(N-Methylpyrrolidino)pyridine
(-)-Nicotine
(-)-Nicotine solution
(2S) 3-(1-Methyl-pyrrolidin-2-yl)-pyridine
(R)-3-(1-Methyl-2-pyrrolidinyl)pyridine
(R,S)-Nicotine
(R,S)-nicotine
(RS)-nicotine
(S)-(-)-NICOTINE, 3-[(2S)-1-METHYL-2-PYRROLIDINYL] PYRIDINE
(S)-(-)-Nicotine
(S)-3-(1-methylpyrrolidin-2-yl)pyridine
(S)-3-(N-methylpyrrolidin-2-yl)pyridine
(S)-Nicotine
(┬▒)-nicotine
)-1-Methyl-2-(3-pyridyl)pyrrolidine
)-Nicotine
)-Nicotine solution
1-Methyl-2-(3-pyridal)-Pyrrolidine
1-Methyl-2-(3-pyridal)-pyrrolidene
1-Methyl-2-(3-pyridiyl)pyrrolidine
1-Methyl-2-(3-pyridyl)pyrrolidine
1uw6
2'-beta-H-Nicotine
3-(1-Methyl-2-pyrollidinyl)pyridine
3-(1-Methyl-2-pyrrolidinyl)-Pyridine
3-(1-Methyl-2-pyrrolidinyl)pyridine
3-(1-Methylpyrrolidin-2-yl)pyridine
3-(2-(N-methylpyrrolidinyl))pyridine
3-(N-Methylpyrollidino)pyridine
3-(N-Methylpyrrolidino)pyridine
3-N-Methylpyrrolidine
3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
36733_FLUKA
36733_RIEDEL
434F7990-3240-4A43-ACEC-E6CC1E495FA0
46343_FLUKA
46343_RIEDEL
54-11-5
AC1L3I79
AC1Q3ZOC
AI3-03424
American Fare Nicotine Transdermal System
BB_NC-0777
BIDD:GT0599
BRD-K05395900-322-02-1
Black Leaf
Black Leaf 40
C00745
CCRIS 1637
CHEBI:17688
CHEMBL3
CID89594
CPD000059074
Campbell's Nico-Soap
Careone Nicotine Transdermal System Step 1
Careone Nicotine Transdermal System Step 2
Careone Nicotine Transdermal System Step 3
Caswell No. 597
Commit
D-Nicotine
D03365
DL-tetrahydronicotyrine
Destruxol
Destruxol Orchid Spray
EINECS 200-193-3
ENT 3,424
EPA Pesticide Chemical Code 056702
Emo-Nik
Equaline Nicotine Transdermal System STEP 1
Exchange Select Nicotine Transdermal System STEP 3
Flux Maag
Fumeto bac
Fumetobac
HSDB 1107
Habitrol
Habitrol (TN)
Habitrol Patch Nicotine Transdermal System, Step 1
Habitrol Patch Nicotine Transdermal System, Step 2
Habitrol Patch Nicotine Transdermal System, Step 3
Healthmart Nicotine Transdermal System STEP 1
Healthmart Nicotine Transdermal System STEP 2
Healthmart Nicotine Transdermal System STEP 3
Kroger Nicotine Transdermal System STEP 1
Kroger Nicotine Transdermal System STEP 2
Kroger Nicotine Transdermal System STEP 3
L(-)-nicotine
L-3-(1-Methyl-2-pyrrolidyl)pyridine
L-Nicotine
LS-202
Leader Nicotine
Leader Nicotine Transdermal System STEP 1
Leader Nicotine Transdermal System STEP 2
Leader Nicotine Transdermal System STEP 3
MLS001055457
 
MLS001335905
Mach-Nic
Meijer Nicotine Transdermal System STEP 2
Meijer Nicotine Transdermal System Step 1
Meijer Nicotine Transdermal System Step 3
Methyl-2-pyrrolidinyl)pyridine
Micotine
MolPort-000-744-731
N3876_SIGMA
N5511_FLUKA
N5511_SIGMA
NCGC00090693-01
NCGC00090693-02
NCGC00090693-03
NCGC00090693-04
NCGC00090693-05
NCGC00090693-06
NCGC00090693-07
NCT
NICOTINE AND SALTS
NSC 5065
NSC97238
Niagara P.A. Dust
Nic-Sal
Nico-Dust
Nico-Fume
Nicocide
Nicoderm
Nicoderm CQ
Nicoderm Cq
Nicoderm Patch
Nicorette
Nicorette Plus
Nicotin
Nicotina
Nicotina [Italian]
Nicotine
Nicotine (USP)
Nicotine (compounds related to)
Nicotine Alkaloid
Nicotine Patch
Nicotine Polacrilex
Nicotine TRANSDERMAL SYSTEM
Nicotine Transdermal System PATCH KIT
Nicotine Transdermal System STEP 1
Nicotine Transdermal System STEP 2
Nicotine Transdermal System STEP 3
Nicotine Transdermal System Step 1
Nicotine Transdermal System Step 2
Nicotine Transdermal System Step 3
Nicotine [BSI:ISO]
Nicotine [UN1654]
Nicotine [UN1654] [Poison]
Nicotine [USAN]
Nicotine transdermal system
Nicotrol
Nicotrol (professional Sample)
Nicotrol Inhaler
Nicotrol Ns
Nictoine patch
Nikotin
Nikotin [German]
Nikotyna
Nikotyna [Polish]
Ortho N-4 Dust
Ortho N-5 Dust
PDSP1_000113
PDSP1_000465
PDSP2_000463
PDSP2_000555
Prostep
R)-(+)-Nicotine
RCRA waste no. P075
RCRA waste number P075
Rite Aid Nicotine Transdermal System Step 1
Rite Aid Nicotine Transdermal System Step 2
Rite Aid Nicotine Transdermal System Step 3
SAM002564224
SDCCGMLS-0066911.P001
SMR000059074
Safeway Nicotine Transdermal System STEP 1
Safeway Nicotine Transdermal System STEP 2
Safeway Nicotine Transdermal System STEP 3
Smart Sense Nicotine
Sunmark Nicotine
Sunmark Nicotine Transdermal System STEP 1
Sunmark Nicotine Transdermal System STEP 2
Sunmark Nicotine Transdermal System STEP 3
Tendust
Transdermal Nicotine
UN1654
a -N-Methylpyrrolidine
a-N-Methylpyrrolidine
alpha-N-Methylpyrrolidine
beta-Pyridyl-alpha-N-methyl pyrrolidine
beta-Pyridyl-alpha-N-methylpyrrolidine
bmse000105
delta-Nicotine
nicotine
nicotine replacement patch

Interventional clinical trials:

(show all 26)
idNameStatusNCT IDPhase
1Open-Label Study of the Long Term Tolerability and Safety of Atomoxetine in Children With FASD and ADD/ADHDRecruitingNCT00418262Phase 3
2Epigallocatechin Gallate (EGCG) to Improve Cognitive Performance in Foetal Alcohol Syndrome (FAS) ChildrenRecruitingNCT02558933Phase 2, Phase 3
3Assess the Effectiveness of Atomoxetine in Children With Fetal Alcohol Syndrome and ADD/ADHDActive, not recruitingNCT00417794Phase 3
4Choline Supplementation in Children With Fetal Alcohol Spectrum DisordersCompletedNCT01911299Phase 2
5Fetal Alcohol Syndrome/ARND Research ConsortionCompletedNCT00164554Phase 1, Phase 2
6Fetal Alcohol Syndrome: Socio-Cognitive HabilitationCompletedNCT00164229Phase 1, Phase 2
7Neurocognitive Habilitation for Children With Fetal Alcohol Syndrome (FAS)/Alcohol-Related Neurodevelopmental Disorder (ARND)CompletedNCT00164346Phase 1, Phase 2
8A Media Based Motivational Intervention to Prevent Alcohol Exposed Pregnancies (AEPs)CompletedNCT00219336Phase 2
9Postnatal Choline Supplementation in Children With Prenatal Alcohol ExposureCompletedNCT01149538Phase 1, Phase 2
10Project CHOICES Efficacy StudyCompletedNCT00153478Phase 2
11Neighborhood Alcohol & HIV Prevention in South African Townships (Philani)Active, not recruitingNCT00996528Phase 2
12Development of Education Materials for Prevention of FAS in RussiaCompletedNCT01971398
13Improving Self Regulation in Children With Fetal Alcohol Syndrome Spectrum Disorders: A Neuroplastic InterventionCompletedNCT02457676
14Preventing FAS/ARND in Russian ChildrenCompletedNCT01961050
15Expansion to Interdisciplinary HIV Prevention in WomenCompletedNCT01994603
16Fetal Alcohol Damage Prevention StudyCompletedNCT00696085
17Healthy Moms Alcohol InterventionCompletedNCT00244062
18Effects of Hyperbaric Oxygen Therapy in Autistic Children: A Pilot StudyCompletedNCT00324909
19Reducing Alcohol Exposed Pregnancy Risk: EARLY Randomized Controlled TrialCompletedNCT01446653
20Comprehensive Program for Youth Mental HealthCompletedNCT02169960
21Parenting Training for Children With FASDRecruitingNCT02210455
22Contraception and Alcohol Risk Reduction Internet Intervention Randomized TrialRecruitingNCT02128880
23Evaluating the Effectiveness of an Attachment-Focused Intervention in Preschool Children With FASDActive, not recruitingNCT01536184
24Prenatal Alcohol Biomarker Study in UruguayNot yet recruitingNCT02600624
25Modeling and Testing Change in Mental Abilities in ChildhoodNot yet recruitingNCT02459873
26Evaluating the Efficacy of a Video Based Intervention to Educate Teen Moms About Fetal Alcohol Syndrome (FAS)TerminatedNCT00747630Phase 0

Search NIH Clinical Center for Fetal Alcohol Syndrome

Genetic Tests for Fetal Alcohol Syndrome

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Anatomical Context for Fetal Alcohol Syndrome

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MalaCards organs/tissues related to Fetal Alcohol Syndrome:

33
Eye, Breast, Placenta, Brain, Testes, Skin, Liver

Animal Models for Fetal Alcohol Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Fetal Alcohol Syndrome:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.2ALDH2, CHRM3, GFAP, L1CAM, PFAS, RBP1
2MP:00053867.1ALDH2, CHRM3, GFAP, GRIN2A, GRIN2B, L1CAM
3MP:00036316.3ADNP, ALDH2, CHRM3, GFAP, GRIN2A, GRIN2B

Publications for Fetal Alcohol Syndrome

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Articles related to Fetal Alcohol Syndrome:

(show top 50)    (show all 520)
idTitleAuthorsYear
1
Fetal alcohol syndrome (FAS) and fetal alcohol spectrum disorder (FASD)-diagnosis and moral policing; an ethical dilemma for paediatricians. (25005521)
2014
2
A potential molecular target for morphological defects of fetal alcohol syndrome: Kir2.1. (23756044)
2013
3
Health care burden and cost associated with fetal alcohol syndrome: based on official Canadian data. (22900084)
2012
4
Teaching NeuroImages: Schizencephaly in fetal alcohol syndrome. (22025464)
2011
5
Tissue plasminogen activator is required for the development of fetal alcohol syndrome in mice. (21383198)
2011
6
Fetal alcohol syndrome: cardiac birth defects in mice and prevention with folate. (20451895)
2010
7
Fetal alcohol syndrome and fetal alcohol spectrum disorder in Indigenous schoolchildren. (19296803)
2009
8
Maternal risk factors for fetal alcohol syndrome and partial fetal alcohol syndrome in South Africa: a third study. (18336634)
2008
9
Automated diagnosis of fetal alcohol syndrome using 3D facial image analysis. (18713153)
2008
10
Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome. (18366608)
2008
11
Impaired eyeblink conditioning in children with fetal alcohol syndrome. (18162064)
2008
12
Reprogramming of genetic networks during initiation of the Fetal Alcohol Syndrome. (17200951)
2007
13
Stereo image matching for facial feature measurement to aid in fetal alcohol syndrome screening. (16904364)
2007
14
Ethanol impairs Rho GTPase signaling and differentiation of cerebellar granule neurons in a rodent model of fetal alcohol syndrome. (17109064)
2006
15
Using the past to step forward: fetal alcohol syndrome in the Western Cape Province of South Africa. (15983266)
2005
16
Fetal alcohol syndrome. Introduction. (15223535)
2004
17
Increased sibling mortality in children with fetal alcohol syndrome. (15223547)
2004
18
A comparison of fetal alcohol syndrome surveillance network and birth defects surveillance methodology in determining prevalence rates of fetal alcohol syndrome. (14703793)
2003
19
Recognition and management of fetal alcohol syndrome. (14624967)
2003
20
From the Centers for Disease Control and Prevention. Fetal alcohol syndrome--Alaska, Arizona, Colorado, and New York, 1995-1997. (12099269)
2002
21
Fetal alcohol syndrome. (20046289)
2002
22
Fetal alcohol syndrome: What you should know about drinking during pregnancy. (20046290)
2002
23
Application of the fetal alcohol syndrome facial photographic screening tool in a foster care population. (12410204)
2002
24
Midaortic syndrome associated with fetal alcohol syndrome. (12427818)
2002
25
Prevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome. (11303069)
2001
26
Gin Lane: did Hogarth know about fetal alcohol syndrome? (11259209)
2001
27
Physician awareness and screening for fetal alcohol syndrome. (11010122)
2000
28
Fetal alcohol syndrome in SALo Paulo, Brazil. (10563369)
1999
29
Neuropsychological comparison of alcohol-exposed children with or without physical features of fetal alcohol syndrome. (9460742)
1998
30
Bone age and growth in fetal alcohol syndrome. (9756047)
1998
31
Contribution to first-pass metabolism of ethanol and inhibition by ethanol for retinol oxidation in human alcohol dehydrogenase family--implications for etiology of fetal alcohol syndrome and alcohol-related diseases. (9652389)
1998
32
Fetal alcohol syndrome update. (9323398)
1997
33
Fetal alcohol syndrome epidemic on Manitoba reserve. (9220946)
1997
34
Fetal alcohol syndrome. (9113456)
1997
35
Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome? (9194424)
1997
36
Ethanol inhibition of retinoic acid synthesis as a potential mechanism for fetal alcohol syndrome. (8801166)
1996
37
A multiple-level, comprehensive approach to the prevention of fetal alcohol syndrome (FAS) and other alcohol-related birth defects (ARBD). (8557409)
1995
38
Neonatal diagnosis of fetal alcohol syndrome: not necessarily a hopeless prognosis. (8749826)
1995
39
Epidemiology of fetal alcohol syndrome in American Indians, Alaskan Natives, and Canadian Aboriginal peoples: a review of the literature. (7938391)
1994
40
Fetal alcohol syndrome: review of the literature with implications for physical therapists. (7689232)
1993
41
Fetal alcohol syndrome--United States, 1979-1992. (8479418)
1993
42
Corneal endothelial anomalies in the fetal alcohol syndrome. (1497528)
1992
43
Fetal alcohol syndrome: a case report of neuropsychological, MRI and EEG assessment of two children. (1443415)
1992
44
Fetal alcohol syndrome: misplaced emphasis. (2058598)
1991
45
Fetal alcohol syndrome in adolescents and adults. (2008025)
1991
46
Fetal alcohol syndrome: a description of oral motor, articulatory, short-term memory, grammatical, and semantic abilities. (2341602)
1990
47
Neuropsychological deficits in fetal alcohol syndrome and fetal alcohol effects. (2264592)
1990
48
Fetal alcohol syndrome: report of one case. (2260467)
1990
49
A cephalometric assessment of children with fetal alcohol syndrome. (2705412)
1989
50
Fetal alcohol syndrome. (3048231)
1988

Variations for Fetal Alcohol Syndrome

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Expression for genes affiliated with Fetal Alcohol Syndrome

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Search GEO for disease gene expression data for Fetal Alcohol Syndrome.

Pathways for genes affiliated with Fetal Alcohol Syndrome

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GO Terms for genes affiliated with Fetal Alcohol Syndrome

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Cellular components related to Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1NMDA selective glutamate receptor complexGO:001714610.0GRIN2A, GRIN2B
2terminal boutonGO:00431959.3GRIN2A, L1CAM, PVALB
3postsynaptic membraneGO:00452119.2CHRM3, GRIN2A, GRIN2B
4neuronal cell bodyGO:00430258.6ADNP, KCNJ2, PVALB, VIP
5dendriteGO:00304258.6ADNP, CHRM3, GRIN2A, KCNJ2

Biological processes related to Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1ethanol oxidationGO:000606910.5ADH1B, ALDH2
2regulation of sensory perception of painGO:005193010.2GRIN2A, VIP
3glutamate receptor signaling pathwayGO:000721510.1GRIN2A, GRIN2B
4startle responseGO:000196410.0GRIN2A, GRIN2B
5regulation of postsynaptic membrane potentialGO:00600789.9GRIN2A, GRIN2B
6excitatory postsynaptic potentialGO:00600799.9GRIN2A, GRIN2B
7ionotropic glutamate receptor signaling pathwayGO:00352359.9GRIN2A, GRIN2B
8regulation of synaptic plasticityGO:00481679.9GRIN2A, GRIN2B
9positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathwayGO:00105799.8CHRM3, VIP
10xenobiotic metabolic processGO:00068059.7ADH1B, AKR1A1, ALDH2
11response to carbohydrateGO:00097439.7ADNP, GRIN2A
12positive regulation of axon extensionGO:00457739.5ADNP, L1CAM
13long-term synaptic potentiationGO:00602919.3GFAP, GRIN2A, GRIN2B
14learning or memoryGO:00076119.2GRIN2A, GRIN2B, VIP
15synaptic transmissionGO:00072688.9ALDH2, GRIN2A, GRIN2B, KCNJ2

Molecular functions related to Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ionotropic glutamate receptor activityGO:00049709.7GRIN2A, GRIN2B
2extracellular-glutamate-gated ion channel activityGO:00052349.7GRIN2A, GRIN2B
3NMDA glutamate receptor activityGO:00049729.6GRIN2A, GRIN2B
4cation channel activityGO:00052619.5GRIN2A, GRIN2B

Sources for Fetal Alcohol Syndrome

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet