FCPD
MCID: FBR065
MIFTS: 25

Fibrocalculous Pancreatopathy (FCPD) malady

Rare diseases, Endocrine diseases categories

Summaries for Fibrocalculous Pancreatopathy

About this section


Wikipedia:64 Fibrocalculous pancreatopathy (FCPP) is a secondary form of diabetes mellitus of unresolved etiology... more...

MalaCards based summary: Fibrocalculous Pancreatopathy, also known as fibrocalculous pancreatic diabetes, is related to pancreatitis and diabetes mellitus. An important gene associated with Fibrocalculous Pancreatopathy is SPINK1 (serine peptidase inhibitor, Kazal type 1). The compounds serine and creatinine have been mentioned in the context of this disorder. Affiliated tissues include pancreas, and related mouse phenotypes are no phenotypic analysis and integument.

Aliases & Classifications for Fibrocalculous Pancreatopathy

About this section
Sources:
48Orphanet, 61UMLS, 27ICD10 via Orphanet
See all sources

Fibrocalculous Pancreatopathy, Aliases & Descriptions:

Name: Fibrocalculous Pancreatopathy 48
Fibrocalculous Pancreatic Diabetes 48 61
 
Tropical Pancreatic Diabetes 48
Fcpd 48


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Endocrine diseases


External Ids:

ICD10 via Orphanet27 E10

Related Diseases for Fibrocalculous Pancreatopathy

About this section

Diseases related to Fibrocalculous Pancreatopathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1pancreatitis31.7SPINK1, INS
2diabetes mellitus30.5INS, SPINK1
3fibrocalculous pancreatic diabetes11.2
4cataract10.3
5hepatitis10.3
6obesity10.3
7autonomic neuropathy10.3
8hemiplegia10.3
9neuropathy10.3
10autonomic dysfunction10.3
11insulin resistance10.3
12infertility10.0INS, SPINK1
13galactosemia9.9SPINK1, INS
14type 2 diabetes mellitus9.9INS, SPINK1
15cystic fibrosis9.9INS, SPINK1
16liver cancer9.9SPINK1, INS
17pancreatic cancer9.8SPINK1, INS
18adenoma9.8SPINK1, INS

Graphical network of diseases related to Fibrocalculous Pancreatopathy:



Diseases related to fibrocalculous pancreatopathy

Symptoms for Fibrocalculous Pancreatopathy

About this section

Drugs & Therapeutics for Fibrocalculous Pancreatopathy

About this section

Drug clinical trials:

Search ClinicalTrials for Fibrocalculous Pancreatopathy

Search NIH Clinical Center for Fibrocalculous Pancreatopathy

Genetic Tests for Fibrocalculous Pancreatopathy

About this section

Anatomical Context for Fibrocalculous Pancreatopathy

About this section

MalaCards organs/tissues related to Fibrocalculous Pancreatopathy:

32
Pancreas

Animal Models for Fibrocalculous Pancreatopathy or affiliated genes

About this section

MGI Mouse Phenotypes related to Fibrocalculous Pancreatopathy:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030129.1INS, SPINK1
2MP:00107719.1INS, SPINK1
3MP:00053819.0INS, SPINK1
4MP:00053798.8INS, SPINK1

Publications for Fibrocalculous Pancreatopathy

About this section

Articles related to Fibrocalculous Pancreatopathy:

idTitleAuthorsYear
1
Histopathological changes of pancreas in patients with fibrocalculous pancreatopathy. (18626456)
2008
2
Juvenile fibrocalculous pancreatopathy--a patient report. (16995576)
2006
3
Lymphoproliferative response to glutamic acid decarboxylase in fibrocalculous pancreatopathy. (11879726)
2002
4
Analysis of the reg1alpha and reg1beta gene transcripts in patients with fibrocalculous pancreatopathy. (12236439)
2002

Variations for Fibrocalculous Pancreatopathy

About this section

Clinvar genetic disease variations for Fibrocalculous Pancreatopathy:

7
id Gene Name Type Significance SNP ID Assembly Location
1SPINK1NM_003122.4(SPINK1): c.101A> G (p.Asn34Ser)single nucleotide variantPathogenic, risk factorrs17107315GRCh37Chr 5, 147207678: 147207678

Expression for genes affiliated with Fibrocalculous Pancreatopathy

About this section
Expression patterns in normal tissues for genes affiliated with Fibrocalculous Pancreatopathy

Search GEO for disease gene expression data for Fibrocalculous Pancreatopathy.

Pathways for genes affiliated with Fibrocalculous Pancreatopathy

About this section

Compounds for genes affiliated with Fibrocalculous Pancreatopathy

About this section
Sources:
44Novoseek
See all sources

Compounds related to Fibrocalculous Pancreatopathy according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1serine449.1INS, SPINK1
2creatinine448.8INS, SPINK1

GO Terms for genes affiliated with Fibrocalculous Pancreatopathy

About this section

Cellular components related to Fibrocalculous Pancreatopathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.1INS, SPINK1

Products for genes affiliated with Fibrocalculous Pancreatopathy

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Fibrocalculous Pancreatopathy

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet