MCID: FBR065
MIFTS: 22

Fibrocalculous Pancreatopathy malady

Rare diseases, Endocrine diseases categories

Aliases & Classifications for Fibrocalculous Pancreatopathy

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Sources:
48Orphanet, 61UMLS, 26ICD10 via Orphanet
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Aliases & Descriptions for Fibrocalculous Pancreatopathy:

Name: Fibrocalculous Pancreatopathy 48
Fibrocalculous Pancreatic Diabetes 48 61
 
Tropical Pancreatic Diabetes 48
Fcpd 48


Classifications:



External Ids:

Orphanet48 99654
ICD10 via Orphanet26 E10

Summaries for Fibrocalculous Pancreatopathy

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Wikipedia:64 Fibrocalculous pancreatopathy (FCPP) is a secondary form of diabetes mellitus of unresolved etiology... more...

MalaCards based summary: Fibrocalculous Pancreatopathy, also known as fibrocalculous pancreatic diabetes, is related to pancreatitis and tropical calcific pancreatitis. An important gene associated with Fibrocalculous Pancreatopathy is SPINK1 (serine peptidase inhibitor, Kazal type 1). The compounds serine and creatinine have been mentioned in the context of this disorder. Affiliated tissues include pancreas, and related mouse phenotypes are no phenotypic analysis and integument.

Related Diseases for Fibrocalculous Pancreatopathy

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Diseases related to Fibrocalculous Pancreatopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
idRelated DiseaseScoreTop Affiliating Genes
1pancreatitis30.3SPINK1, INS
2tropical calcific pancreatitis10.5
3obesity10.3
4cataract10.3
5hepatitis10.3
6autonomic neuropathy10.3
7hemiplegia10.3
8neuropathy10.3
9autonomic dysfunction10.3
10infertility9.9INS, SPINK1
11galactosemia9.9SPINK1, INS
12diabetes mellitus, noninsulin-dependent9.9INS, SPINK1
13cystic fibrosis9.9INS, SPINK1
14diabetes mellitus, insulin-dependent9.9INS, SPINK1
15hepatocellular carcinoma9.9SPINK1, INS
16pancreatic cancer9.8SPINK1, INS
17adenoma9.7SPINK1, INS

Graphical network of diseases related to Fibrocalculous Pancreatopathy:



Diseases related to fibrocalculous pancreatopathy

Symptoms for Fibrocalculous Pancreatopathy

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Drugs & Therapeutics for Fibrocalculous Pancreatopathy

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Drug clinical trials:

Search ClinicalTrials for Fibrocalculous Pancreatopathy

Search NIH Clinical Center for Fibrocalculous Pancreatopathy

Genetic Tests for Fibrocalculous Pancreatopathy

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Anatomical Context for Fibrocalculous Pancreatopathy

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MalaCards organs/tissues related to Fibrocalculous Pancreatopathy:

31
Pancreas

Animal Models for Fibrocalculous Pancreatopathy or affiliated genes

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MGI Mouse Phenotypes related to Fibrocalculous Pancreatopathy:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030129.1INS, SPINK1
2MP:00107719.1INS, SPINK1
3MP:00053819.0INS, SPINK1
4MP:00053798.8INS, SPINK1

Publications for Fibrocalculous Pancreatopathy

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Articles related to Fibrocalculous Pancreatopathy:

idTitleAuthorsYear
1
Histopathological changes of pancreas in patients with fibrocalculous pancreatopathy. (18626456)
2008
2
Juvenile fibrocalculous pancreatopathy--a patient report. (16995576)
2006
3
Lymphoproliferative response to glutamic acid decarboxylase in fibrocalculous pancreatopathy. (11879726)
2002
4
Analysis of the reg1alpha and reg1beta gene transcripts in patients with fibrocalculous pancreatopathy. (12236439)
2002

Variations for Fibrocalculous Pancreatopathy

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Clinvar genetic disease variations for Fibrocalculous Pancreatopathy:

5
id Gene Variation Type Significance SNP ID Assembly Location
1SPINK1NM_003122.4(SPINK1): c.101A> G (p.Asn34Ser)single nucleotide variantPathogenic, risk factorrs17107315GRCh37Chr 5, 147207678: 147207678

Expression for genes affiliated with Fibrocalculous Pancreatopathy

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Search GEO for disease gene expression data for Fibrocalculous Pancreatopathy.

Pathways for genes affiliated with Fibrocalculous Pancreatopathy

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Compounds for genes affiliated with Fibrocalculous Pancreatopathy

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Sources:
44Novoseek
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Compounds related to Fibrocalculous Pancreatopathy according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1serine449.1INS, SPINK1
2creatinine448.8INS, SPINK1

GO Terms for genes affiliated with Fibrocalculous Pancreatopathy

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Cellular components related to Fibrocalculous Pancreatopathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055769.1INS, SPINK1

Sources for Fibrocalculous Pancreatopathy

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet