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MCID: FBR032
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Fibromuscular Dysplasia malady |
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Sources: 31NINDS, 44Wikipedia, 22MalaCards See all sources Export this MalaCard |
NINDS: Fibromuscular dysplasia (FMD) is the abnormal development or growth of cells in the walls of arteries that can cause the vessels
to narrow or bulge. The carotid arteries, which pass through the neck and supply blood to the brain, are commonly affected.
Arteries within the brain and kidneys can also be affected. A characteristic ?string of beads? pattern caused by the alternating
narrowing and enlarging of the artery can block or reduce blood flow to the brain, causing a stroke or mini-stroke. Some patients
experience no symptoms of the disease while others may have high blood pressure, dizziness or vertigo, chronic headache, intracranial
aneurysm, ringing in the ears, weakness or numbness in the face, neck pain, or changes in vision. FMD is most often seen in
persons age 25 to 50 years and affects women more often than men. More than one family member may be affected by the disease.
The cause of FMD is unknown. An angiogram can detect the degree of narrowing or obstruction of the artery and identify changes
such as a tear (dissection) or weak area (aneurysm) in the vessel wall. FMD can also be diagnosed using computed tomography,
magnetic resonance imaging, or ultrasound.31
MalaCards: Fibromuscular Dysplasia is related to renal artery obstruction and hyporeninemic hypoaldosteronism. An important gene associated with Fibromuscular Dysplasia is REN (renin), and among its related pathways are Renin-angiotensin system and Renin-Angiotensin Pathway. The compounds glucose and remikiren have been mentioned in the context of this disorder. Affiliated tissues include brain and kidney, and related mouse phenotypes are muscle and renal/urinary system. Wikipedia: Fibromuscular dysplasia, or fibromuscular dysplasia of arteries, often abbreviated as FMD, is a disease...44 more... |
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Sources: 31NINDS, 8DISEASES, 32Novoseek , 43UMLS See all sources |
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for fibromuscular dysplasia Drug clinical trials:Search ClinicalTrials for fibromuscular dysplasia Search NIH Clinical Center for fibromuscular dysplasia Search CenterWatch for fibromuscular dysplasia |
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Sources: 22MalaCards See all sources |
MalaCards organs/tissues related to fibromuscular dysplasia:22Brain, Kidney
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to fibromuscular dysplasia:25
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Sources: 35PubMed See all sources |
Articles related to fibromuscular dysplasia:
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Sources: 1BioGPS See all sources |
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Sources: 20KEGG, 36QIAGEN, 34PharmGKB See all sources |
Pathways related to fibromuscular dysplasia according to GeneDecks:
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Sources: 32Novoseek , 9DrugBank, 42Tocris Bioscience, 34PharmGKB, 18HMDB See all sources |
Compounds related to fibromuscular dysplasia according to GeneDecks:(show top 50) (show all 93)
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Sources: 12Gene Ontology See all sources |
Cellular components related to fibromuscular dysplasia according to GeneDecks:
Biological processes related to fibromuscular dysplasia according to GeneDecks:(show all 16)
Molecular functions related to fibromuscular dysplasia according to GeneDecks:
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