MCID: FBR001
MIFTS: 27

Fibrous Meningioma malady

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Fibrous Meningioma

Aliases & Descriptions for Fibrous Meningioma:

Name: Fibrous Meningioma 12 52 14 69
Fibroblastic Meningioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7211
MeSH 42 D008579
NCIt 47 C4330
SNOMED-CT 64 511008
UMLS 69 C0334606

Summaries for Fibrous Meningioma

MalaCards based summary : Fibrous Meningioma, also known as fibroblastic meningioma, is related to marfanoid hypermobility syndrome and autosomal recessive stickler syndrome. An important gene associated with Fibrous Meningioma is MUC1 (Mucin 1, Cell Surface Associated), and among its related pathways/superpathways are Cytoskeletal Signaling and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Ifosfamide and Mechlorethamine have been mentioned in the context of this disorder. Affiliated tissues include b cells, and related phenotypes are Decreased cell migration and respiratory system

Related Diseases for Fibrous Meningioma

Diseases related to Fibrous Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 114)
id Related Disease Score Top Affiliating Genes
1 marfanoid hypermobility syndrome 10.2 MUC1 VIM
2 autosomal recessive stickler syndrome 10.2 MUC1 VIM
3 endometrial stromal sarcoma 10.2 MUC1 VIM
4 tanycytic ependymoma 10.2 MUC1 VIM
5 bladder adenocarcinoma 10.2 MUC1 VIM
6 avian influenza 10.2 MUC1 VIM
7 testicular granulosa cell tumor 10.2 MUC1 VIM
8 petrous apex meningioma 10.2 MUC1 VIM
9 vulvar angiokeratoma 10.2 MUC1 VIM
10 lymphangiosarcoma 10.2 MUC1 VIM
11 progeria 10.2 MUC1 VIM
12 coronary stenosis 10.2 MUC1 VIM
13 sebaceous adenoma 10.2 MUC1 VIM
14 anal gland neoplasm 10.2 MUC1 VIM
15 cauda equina intradural extramedullary astrocytoma 10.2 MUC1 VIM
16 gestational trophoblastic neoplasm 10.2 MUC1 VIM
17 appendix mucinous cystadenocarcinoma 10.2 MUC1 VIM
18 mesenchymoma 10.2 MUC1 VIM
19 omodysplasia 2 10.2 MUC1 VIM
20 subependymal glioma 10.2 MUC1 VIM
21 congenital muscular dystrophy with hyperlaxity 10.2 MUC1 VIM
22 differentiating neuroblastoma 10.2 MUC1 VIM
23 congenital myasthenic syndrome 10.2 F13A1 VIM
24 cortical blindness 10.2 F13A1 VIM
25 lung benign neoplasm 10.2 MUC1 VIM
26 ovarian insufficiency due to fsh resistance 10.2 MUC1 VIM
27 hematologic cancer 10.2 F13A1 VIM
28 orthostatic proteinuria 10.1 MUC1 VIM
29 central nervous system embryonal carcinoma 10.1 MUC1 NF2
30 pericardial mesothelioma 10.1 MUC1 VIM
31 ovarian papillary neoplasm 10.1 MUC1 VIM
32 myxopapillary ependymoma 10.1 NF2 VIM
33 scirrhous adenocarcinoma 10.1 MUC1 VIM
34 tumor of exocrine pancreas 10.1 MUC1 NF2
35 kidney benign neoplasm 10.1 MUC1 VIM
36 human granulocytic anaplasmosis 10.1 MUC1 VIM
37 lucey-driscoll syndrome 10.1 MUC1 S100B
38 secondary pulmonary hemosiderosis 10.1 MUC1 S100B
39 myelinoclastic diffuse sclerosis 10.1 MUC1 S100B
40 invasive mole 10.1 MUC1 S100B
41 caroli disease 10.1 F13A1 VIM
42 pemphigus vegetans 10.1 MUC1 S100B
43 ovarian cystadenoma 10.1 MUC1 S100B
44 trombiculiasis 10.1 MUC1 S100B
45 corneal intraepithelial neoplasm 10.1 MUC1 S100B
46 endocardium cancer 10.1 MUC1 S100B
47 precursor t-lymphoblastic lymphoma/leukemia 10.1 MUC1 S100B
48 lupus - neurological sequelae 10.1 S100B VIM
49 benign schwannoma 10.0 S100B VIM
50 sarcomatoid renal cell carcinoma 10.0 MUC1 VIM

Graphical network of the top 20 diseases related to Fibrous Meningioma:



Diseases related to Fibrous Meningioma

Symptoms & Phenotypes for Fibrous Meningioma

GenomeRNAi Phenotypes related to Fibrous Meningioma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased cell migration GR00055-A-1 8.8 MUC1 NF2 VIM

MGI Mouse Phenotypes related to Fibrous Meningioma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 8.92 CTSH F13A1 NF2 VIM

Drugs & Therapeutics for Fibrous Meningioma

Drugs for Fibrous Meningioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ifosfamide Approved Phase 2 3778-73-2 3690
2
Mechlorethamine Approved Phase 2 51-75-2 4033
3 Alkylating Agents Phase 2
4 Isophosphamide mustard Phase 2
5 Antineoplastic Agents, Alkylating Phase 2
6
Doxorubicin Approved, Investigational Phase 1 23214-92-8 31703
7
Doxil Approved June 1999 Phase 1 31703
8 Topoisomerase Inhibitors Phase 1
9 Anti-Bacterial Agents Phase 1
10 Liver Extracts Phase 1
11 Antibiotics, Antitubercular Phase 1

Interventional clinical trials:


id Name Status NCT ID Phase
1 S9624 Ifosfamide in Treating Patients With Meningeal Tumors Terminated NCT00003292 Phase 2
2 Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors Completed NCT00019630 Phase 1

Search NIH Clinical Center for Fibrous Meningioma

Genetic Tests for Fibrous Meningioma

Anatomical Context for Fibrous Meningioma

MalaCards organs/tissues related to Fibrous Meningioma:

39
B Cells

Publications for Fibrous Meningioma

Articles related to Fibrous Meningioma:

id Title Authors Year
1
Multiple meningiomas consisting of fibrous meningioma, transitional meningioma, and meningotheliomatous meningioma in one adult patient. ( 26425174 )
2015
2
Marginal zone B-cell lymphoma involving a longstanding fibrous meningioma: an initial manifestation of systemic disease. ( 23850496 )
2013
3
Unusual fibrous meningioma in a patient with sarcoidosis: central necrosis associated with multinucleated giant cells. ( 21176717 )
2011
4
Meningioangiomatosis associated with fibrous meningioma in a dog. ( 19525526 )
2009
5
Multiple meningiomas consisting of fibrous meningioma and anaplastic meningioma. ( 12948473 )
2003
6
Fibrous meningioma in a patient with von Hippel-Lindau disease: a genetic analysis. ( 11765821 )
2001
7
Clinicopathological features of solitary fibrous tumor of the meninges: An immunohistochemical reappraisal of cases previously diagnosed to be fibrous meningioma or hemangiopericytoma. ( 11107053 )
2000
8
Fibrous meningioma with tyrosine-rich crystals. ( 10582272 )
1999
9
The immunophenotypic spectrum of meningeal hemangiopericytoma: a comparison with fibrous meningioma and solitary fibrous tumor of meninges. ( 9351573 )
1997
10
Solitary fibrous tumor of the meninges: a lesion distinct from fibrous meningioma. A clinicopathologic and immunohistochemical study. ( 8712177 )
1996

Variations for Fibrous Meningioma

Expression for Fibrous Meningioma

Search GEO for disease gene expression data for Fibrous Meningioma.

Pathways for Fibrous Meningioma

Pathways related to Fibrous Meningioma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.61 MUC1 NF2 VIM
2 11.06 S100B VIM
3 10.86 F13A1 MUC1 VIM

GO Terms for Fibrous Meningioma

Cellular components related to Fibrous Meningioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 ruffle GO:0001726 8.62 NF2 S100B

Sources for Fibrous Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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