Aliases & Classifications for Focal Dystonia

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Aliases & Descriptions for Focal Dystonia:

Name: Focal Dystonia 11 46 13 25 48 66
Ftsd 46 24
Dystonia, Focal, Task-Specific 66
Focal Task Specific Dystonia 46
Task-Specific Focal Dystonia 24
 
Focal Task-Specific Dystonia 24
Task-Specific Dystonia 24
Occupational Dystonia 24
Focal Hand Dystonia 24
Occupational Cramp 24

Classifications:



External Ids:

Disease Ontology11 DOID:0050836

Summaries for Focal Dystonia

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NIH Rare Diseases:46 Focal dystonia is a movement disorder that is localized to a specific part of the body. the dystonias are a group of movement problems characterized by involuntary, sustained muscle contractions, tremors, and other uncontrolled movements. focal task-specific dystonia, or ftsd, interferes with the performance of particular tasks, such as writing, playing a musical instrument, or participating in a sport. additionally, ftsd has been reported in tailors, shoemakers, hair stylists, and people who frequently type or use a computer mouse. while the abnormal movements associated with focal dystonia are usually painless, they can cause high levels of anxiety. the causes of focal dystonia are unknown, although the disorder likely results from a combination of genetic and environmental factors. it is possible that the different forms of ftsd have different underlying causes. researchers have found that at least some cases are related to malfunction of the basal ganglia, which are structures deep within the brain that help start and control movement. most cases of focal dystonia are sporadic, which means they occur in people with no history of the condition in their family. however, at least 10 percent of affected individuals have a family history which seems to follow an autosomal dominant pattern of inheritance. last updated: 9/11/2013

MalaCards based summary: Focal Dystonia, also known as ftsd, is related to cervical dystonia and cranio-facial dystonia, and has symptoms including dystonia, dystonia, paroxysmal and dystonia, limb. An important gene associated with Focal Dystonia is DRD5 (Dopamine Receptor D5), and among its related pathways is Dopamine-DARPP32 Feedback onto cAMP Pathway. Affiliated tissues include brain, cortex and spinal cord, and related mouse phenotype behavior/neurological.

Disease Ontology:11 A dystonia that is localized to a specific part of the body.

Genetics Home Reference:24 Task-specific focal dystonia is a movement disorder that interferes with the performance of particular tasks, such as writing, playing a musical instrument, or participating in a sport. Dystonias are a group of movement problems characterized by involuntary, sustained muscle contractions, tremors, and other uncontrolled movements. The term "focal" refers to a type of dystonia that affects a single part of the body, such as the hand or jaw.

Wikipedia:69 Focal dystonia is a neurological condition that affects a muscle or group of muscles in a specific part... more...

Related Diseases for Focal Dystonia

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Diseases related to Focal Dystonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 72)
idRelated DiseaseScoreTop Affiliating Genes
1cervical dystonia30.3CIZ1, SGCE, THAP1, TOR1A
2cranio-facial dystonia30.2THAP1, TOR1A
3oromandibular dystonia30.2DRD5, THAP1, TOR1A
4oculogyric crisis29.2CIZ1, DRD5, GNAL, HLA-DRB1, TOR1A
5dystonia 2511.3
6dystonia10.9
7blepharospasm10.5
8limbic encephalitis10.3TIMM8A, TOR1A
9aberrant subclavian artery10.3THAP1, TOR1A
10x-linked dystonia-parkinsonism/lubag10.3THAP1, TOR1A
11charcot-marie-tooth disease, x-linked recessive, 510.1ANO3, TIMM8A
12hemifacial spasm10.1
13blepharospasm, primary benign10.1
14dystonia 2410.1
15partington syndrome10.1
16ataxia10.0
17cervicitis9.9
18cerebritis9.9
19tremor9.9
20dystonia-1, torsion9.9
21focal hand dystonia9.9
22spasmodic dystonia9.9
23miller fisher syndrome9.9SGCE, TBP
24obstructive sleep apnea9.9SGCE, THAP1, TOR1A
25intermittent explosive disorder9.8DRD2, DRD5
26irritant dermatitis9.7DRD2, DRD5
27acinar cell carcinoma9.7DRD2, DRD5
28hemidystonia9.7ANO3, GNAL, THAP1, TOR1A
29cerebellar ataxia9.7
30spinocerebellar ataxia 179.7
31obsessive-compulsive disorder9.7
32wilson disease9.7
33creutzfeldt-jakob disease9.7
34mohr-tranebjaerg syndrome9.7
35brain injury9.7
36spinal stenosis9.7
37traumatic brain injury9.7
38restless legs syndrome9.7
39vitamin b12 deficiency9.7
40scoliosis9.7
41idiopathic scoliosis9.7
42siderosis9.7
43epilepsy9.7
44focal epilepsy9.7
45kallmann syndrome9.7
46ulnar neuropathy9.7
47central pontine myelinolysis9.7
48localized scleroderma9.7
49neuropathy9.7
50encephalitis9.7

Graphical network of the top 20 diseases related to Focal Dystonia:



Diseases related to focal dystonia

Symptoms for Focal Dystonia

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UMLS symptoms related to Focal Dystonia:


dystonia, dystonia, paroxysmal, dystonia, limb

Drugs & Therapeutics for Focal Dystonia

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Drugs for Focal Dystonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AcetylcholinePhase 4, Phase 3, Phase 2, Phase 175251-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
2
RopivacainePhase 470984057-95-471273, 175805
Synonyms:
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
(S)-(−)-1-propyl-2',6'-pipecoloxylidide
(S)-ropivacaine
84057-95-4
98717-15-8
AC1L41QM
AC1L41QN
BIDD:GT0203
C07532
C17H26N2O.HCl
CHEBI:8890
CHEMBL1077896
CID175804
CID175805
CPD000469137
D08490
I14-176
L-N-n-propylpipecolic acid-2,6-xylidide
LS-113954
 
MLS001401363
MolPort-003-983-292
NCGC00164597-01
Naropin
Naropin (TN)
ROPIVACAINE HCl
Ropivacaina
Ropivacaina [INN-Spanish]
Ropivacaina [Spanish]
Ropivacaine
Ropivacaine [INN]
Ropivacaine hydrochloride
Ropivacaine monohydrochloride
Ropivacainum
Ropivacainum [INN-Latin]
S-Ropivacaine
SAM001246524
SMR000469137
ST51051452
ropivacaine monohydrochloride,
ropivacaine monohydrochloride, (S)-isomer
3
IbuprofenPhase 448215687-27-13672
Synonyms:
(+-)-2-(P-Isobutylphenyl)propionic acid
(+-)-Ibuprofen
(+-)-P-Isobutylhydratropic acid
(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid
(4-Isobutylphenyl)-alpha-methylacetic acid
(RS)-ibuprofen
139466-08-3
15687-27-1
2-(4-Isobutylphenyl)propanoic acid
4-Isobutylhydratropic acid
58560-75-1
AC-11312
AC1L1GGE
AC1Q1P84
AC1Q1P85
ACHES-N-PAIN
ARONIS23835
Act-3
Actiprofen
Adex 200
Adran
Advil
Advil (TN)
Advil Liqui-Gels
Ak+C2278tren
Alaxan
Algofen
Am-Fam 400
Amelior
Amersol
Amibufen
Anafen
Anco
Andran
Anflagen
Antagil
Antalfene
Antarene
Antiflam
Apo-Ibuprofen
Apsifen
Apsifen-F
Artofen
Artril
Artril 300
BB_SC-1358
BIDD:GT0050
BRN 2049713
Balkaprofen
Betaprofen
Bloom
Bluton
Brofen
Brufanic
Brufen
Brufen 400
Bruflam
Brufort
Buburone
Bufeno
Bufigen
Bukrefen
Bupron
Buracaps
Burana
Butylenin
C01588
C13H18O2
CCRIS 3223
CHEBI:5855
CHEMBL521
CID3672
CPD000058184
Cap-Profen
Carol
Cesra
Children's Advil
Children's Elixsure
Children's Ibuprofen
Children's Motrin
Citalgan
Cobo
Codral
Combiflam
Cunil
D00126
D007052
DB01050
DOLO PUREN
Daiprophen
Dalsy
Dansida
Deep Relief
Dentigoa
Dibufen
Dignoflex
Dolgin
Dolgirid
Dolgit
Dolibu
Dolmaral
Dolo-Dolgit
Dolo-dolgit
Dolocyl
Dolofen
Dolofen-F
Dolofin
Dolofort
Dologel
Dolomax
Doloren
Dolormin
Doltibil
Dolven
Donjust B
Dorival
Drin
Duafen
Duobrus
Dura-Ibu
Duralbuprofen
Dysdolen
EU-0100691
Easifon
Ebufac
Emflam
Emflam-200
Emodin
Epobron
Eputex
Ergix
Esprenit
Exneural
Faspic
Femadon
Femafen
Femapirin
Femidol
Fenbid
Fenbid Spansule
Fendol
Fenspan
Fibraflex
Gelufene
Gofen
Grefen
Gynofug
HMS1920F15
HMS2089P05
HMS2091N03
HMS502M09
HSDB 3099
Haltran
I 4883
I01-7039
I0415
I4883_SIGMA
I7905_SIAL
IB-100
IDI1_000887
IP 82
IP-82
IP82
Ibol
Ibren
Ibu
Ibu-Attritin
Ibu-Slo
Ibu-Tab
Ibu-Tab 200
Ibu-attritin
Ibu-slo
Ibu-slow
Ibubest
Ibubeta
Ibucasen
Ibudol
 
Ibudolor
Ibufen
Ibuflamar
Ibufug
Ibugel
Ibugen
Ibugesic
Ibuhexal
Ibulagic
Ibular
Ibulav
Ibuleve
Ibulgan
Ibumed
Ibumerck
Ibumetin
Ibupirac
Ibuprin
Ibuprocin
Ibuprofen
Ibuprofene
Ibuprofeno
Ibuprofenum
Ibuprohm
Ibuprophen
Ibusal
Ibutid
Ifen
Inabrin
Inflam
Inoven
Ipren
Irfen
Isodol
Jenaprofen
Junifen
Junior Strength Advil
Junior Strength Ibuprofen
Junior Strength Motrin
KBio1_000887
KBio2_001329
KBio2_003897
KBio2_006465
KBio3_001390
Kesan
Kratalgin
LS-7454
Lamidon
Lebrufen
Librofem
Lidifen
Liptan
Lopane
MLS000069733
MLS001146965
Malafene
Manypren
Medipren
Melfen
Mensoton
Midol
Midol 200
Moment
Motrin
Motrin (TN)
Motrin IB
Mynosedin
NCI60_002065
NINDS_000887
NSC 256857
NSC256857
Nagifen-D
Napacetin
Narfen
Neo-Helvagit
Neo-Mindol
NeoProfen
Neobrufen
Nerofen
Noalgil
Nobafon
Nobfelon
Nobfen
Nobgen
Noritis
Norton
Novadol
Novo-Profen
Novogent
Novogent N
Novoprofen
Nuprilan
Nuprin
Nurofen
Optifen
Opturem
Oralfene
Ostarin
Ostofen
Ozonol
P-Isobutylhydratropic Acid
Paduden
Panafen
Pantrop
Para-Isobutylhydratropic Acid
Paxofen
Pedia-Profen
PediaProfen
Pediaprofen
Pediatric Advil
Perofen
Proartinal
Profen
Proflex
Provon
Quadrax
R.D. 13621
RD 13621
Rafen
Ranofen
Rebugen
Relcofen
Rhinadvil
Rofen
Roidenin
Rufen
Rufin
Rupan
SAM002264619
SMR000058184
SPBio_000178
STK177358
Sadefen
Salivia
Salprofen
Seclodin
Sednafen
Seklodin
Seskafen
Siyafen
Solpaflex
Solufen
Stelar
Sugafen
Suprafen
Suspren
Syntofene
TL8001184
Tab-Profen
Tabalon
Tabalon 400
Tatanal
Tempil
Tofen
Togal N
Tonal
Trendar
U 18573
U-18,573
U-18573
UCB 79171
Unipron
Upfen
Uprofen
Urem
VUFB 9649
Zafen
Zofen
alpha-(4-Isobutylphenyl)propionate
alpha-(4-Isobutylphenyl)propionic acid
alpha-(P-Isobutylphenyl)propionic acid
alpha-p-Isobutylphenylpropionate
alpha-p-Isobutylphenylpropionic acid
ibuprofen
p-Isobutyl-2-phenylpropionate
p-Isobutyl-2-phenylpropionic acid
p-Isobutylhydratropate
p-Isobutylhydratropic acid
4
FentanylPhase 4739437-38-73345
Synonyms:
1-Phenethyl-4-(N-phenylpropionamido)piperidine
1-Phenethyl-4-N-propionylanilinopiperidine
437-38-7
5-22-08-00049 (Beilstein Handbook Reference)
80832-90-2
990-73-8 (citrate)
AC1L1FQ2
Actiq
BIDD:GT0555
BRN 0494484
CHEBI:119915
CHEMBL596
CID3345
D00320
DB00813
Duragesic
Duragesic (TN)
Duragesic-100
Duragesic-12
Duragesic-25
Duragesic-50
Duragesic-75
Durogesic
EINECS 207-113-6
Fentanest
Fentanil
Fentanil [DCIT]
Fentanila
Fentanila [INN-Spanish]
Fentanilo
Fentanyl
Fentanyl (JAN/USAN/INN)
Fentanyl [INN:BAN]
Fentanyl citrate
Fentanyl-100
 
Fentanyl-12
Fentanyl-25
Fentanyl-50
Fentanyl-75
Fentanylum
Fentanylum [INN-Latin]
HSDB 3329
IONSYS
JNS020QD
L001275
LS-124439
Matrifen
MolPort-003-847-369
N-(1-Phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-Phenethyl-4-piperidyl)propionanilide
N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide
N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropanamide
N-Phenethyl-4-(N-propionylanilino)piperidine
N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
NCGC00168252-01
Nasalfent
Oprea1_152073
Oprea1_207148
PDSP1_000860
PDSP2_000846
Pentanyl
Phentanyl
Propanamide, N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)- (9CI)
R 4263
Rapinyl
Sentonil
Sublimase
Sublimaze
UNII-UF599785JZ
fentanyl
5
MexiletinePhase 22031828-71-44178
Synonyms:
(+-)-1-(2,6-Dimethylphenoxy)propan-2-amine
(+-)-1-(2,6-dimethylphenoxy)propan-2-amine
(2RS)-1-(2,6-dimethylphenoxy)-2-aminopropane
1-(2',6'-Dimethylphenoxy)-2-aminopropane
1-(2,6-Dimethylphenoxy)-2-propanamine
1-(2,6-dimethylphenoxy)propan-2-amine
1-Methyl-2-(2,6-xylyloxy)ethanamine
1-Methyl-2-(2,6-xylyloxy)ethylamine
1-methyl-2-(2,6-xylyloxy)ethanamine
2-(2-Aminopropoxy)-1,3-DiMethyl-Benzene Hydrochloride
2-(2-aminopropoxy)-1,3-dimethylbenzene
31828-71-4
5370-01-4 (hydrochloride)
AB00053683
AC1L1HL7
AC1Q2BC5
AC1Q2BC6
BPBio1_000026
BRD-A64092382-003-04-3
BRN 2092205
BSPBio_000022
BSPBio_002254
C07220
CHEBI:115958
CHEBI:6916
CHEMBL558
CID4178
D08215
DB00379
DivK1c_000834
EINECS 250-825-7
I01-6374
IDI1_000834
KBio1_000834
KBio2_002082
KBio2_004650
 
KBio2_007218
KBio3_001474
KBioGR_001270
KBioSS_002082
KO-1173
KO1173
KOE-1173
LS-68257
Lopac0_000784
Mexiletene
Mexiletina
Mexiletina [INN-Spanish]
Mexiletine
Mexiletine (INN)
Mexiletine HCL
Mexiletine [INN:BAN]
Mexiletinum
Mexiletinum [INN-Latin]
Mexilitine
Mexilétine
Mexitil
Mexityl
MolPort-001-790-944
NCGC00015659-04
NCGC00162253-01
NCGC00162253-02
NINDS_000834
Prestwick0_000241
Prestwick1_000241
Prestwick2_000241
Prestwick3_000241
SBB070242
SPBio_002241
Spectrum3_000727
Spectrum4_000795
Spectrum5_001279
Spectrum_001602
UNII-1U511HHV4Z
6
AmlodipinePhase 246488150-42-92162
Synonyms:
()-Amlodipine
(RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)
3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(O-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (.+/-.)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
88150-42-9
88150-47-4 (maleate (1:1))
AC-4535
AC1L1D26
AC1Q32ZS
AMLODIPINE BASE
AMVAZ
Ambap88150-42-9
Amlocard
Amlodipine
Amlodipine (INN)
Amlodipine Benzenesulfonate
Amlodipine Besilate
Amlodipine Besylate
Amlodipine Free Base
Amlodipine [INN:BAN]
Amlodipine besilate
Amlodipine besylate
Amlodipine free base
Amlodipino
Amlodipino [Spanish]
Amlodipinum
Amlodipinum [Latin]
Amlodis
Amlopres
Amlor
 
Amvaz
BIDD:GT0810
BRD-A22032524-074-02-4
BRD-A22032524-074-03-2
BSPBio_002727
C06825
CHEBI:2668
CHEMBL1491
CID2162
CPD000469198
Coroval
D07450
DB00381
HMS2052N03
HMS2089H07
I14-0798
Intervask
Istin
KBio3_001947
KBioGR_001643
LS-131183
Lipinox
Lotrel
MLS001401409
MolPort-001-792-963
NCGC00165957-01
NCGC00165957-02
NCGC00165957-03
Norvasc
Norvasc (TN)
Pelmec
R,S)-Amlodipine
Racemic Amlodipine
SAM001246705
SMR000469198
SPBio_000351
Spectrum2_000486
Spectrum3_001004
Spectrum4_001132
Spectrum5_001550
UK-4834011
UNII-1J444QC288
amlodipine
7calcium channel blockersPhase 21889
8
Flumazenil2578755-81-43373
Synonyms:
4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-, ethyl ester
78755-81-4
8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester
AC-6846
AC1L1FSE
AC1Q33UE
Anexate
BIDD:GT0766
BPBio1_001190
BRD-K98769987-001-01-3
BRN 4763661
Biomol-NT_000285
C07825
C15H14FN3O3
CHEBI:5103
CHEMBL407
CID3373
CPD000058450
D005442
D00697
DB01205
EU-0100506
Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate
Ethyl 8-fluoro-5-methyl-5,6-dihydro-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate
Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
F 6300
F6300_SIGMA
Flumazenil (JAN/USP/INN)
Flumazenil [USAN:BAN:INN]
Flumazenilo
Flumazenilo [Spanish]
Flumazenilum
Flumazenilum [Latin]
Flumazepil
Flumazepil, Ro 15-1788, Anexate, Lanexat, Mazicon, Roma,Flumazenil
HMS2051D17
HMS2089B15
Hoffman La Roche Brand of Flumazenil
Hoffman-La Roche Brand of Flumazenil
I01-0379
LS-77778
 
Lanexat
Lopac-F-6300
Lopac0_000506
MLS000028850
MLS000759529
MLS001076354
Mazicon
MolPort-003-666-855
NCGC00015439-01
NCGC00015439-03
NCGC00015439-07
NCGC00025116-01
NCGC00025116-02
NCGC00025116-03
NCGC00025116-04
NCGC00025116-05
PDSP1_001778
PDSP2_001761
RO-151788
Ro 15 1788
Ro 15-1788
Ro 151788
Ro-15-1788
Ro-?15-1788
Ro15-1788
Roche Brand of Flumazenil
Romazicon
Romazicon (TN)
S1332_Selleck
SAM001246763
SBB063113
SMR000058450
TL8005362
Tocris-1328
UNII-40P7XK9392
UPCMLD-DP137
UPCMLD-DP137:001
ZINC00001464
[3H]Ro15-1788
ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
flumazenil
nchembio747-comp37
9
Dopamine367851-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8

Interventional clinical trials:

(show top 50)    (show all 59)
idNameStatusNCT IDPhase
1Quantifying Musical Performance After Treatment With Myobloc in Musician's DystoniaCompletedNCT00208091Phase 4
2Ultrasound Guided Intermediate Cervical Plexus Block for Congenital Muscular TorticollisRecruitingNCT02651311Phase 4
3Comparison of Electrophysiologic and Ultrasound Guidance for Onabotulinum Toxin A Injections in Focal Upper Extremity Dystonia and SpasticityRecruitingNCT02326818Phase 3
4Amlodipine Plus Botulinum Toxin for Focal DystoniaCompletedNCT00015457Phase 2
5Mexiletine for the Treatment of Focal DystoniaCompletedNCT00001784Phase 2
6Motor Training to Treat Hand DystoniaCompletedNCT00021853Phase 2
7Brain Stimulation to Treat Blepharospasm or Meige SyndromeCompletedNCT00411255Phase 2
8A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of BlepharospasmCompletedNCT00942851Phase 1, Phase 2
9rTMS and Retraining in Focal Hand DystoniaCompletedNCT01738581Phase 1, Phase 2
10Transcranial Electrical Polarization to Treat Focal Hand DystoniaCompletedNCT00106782Phase 2
11Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer's CrampCompletedNCT02015039Phase 1, Phase 2
12Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician's HandRecruitingNCT02107261Phase 2
13Deep Brain Stimulation Surgery for Focal Hand DystoniaNot yet recruitingNCT02911103Phase 1, Phase 2
14Safety and Tolerability of Perampanel in Cervical DystoniaNot yet recruitingNCT02131467Phase 1, Phase 2
15Acetyl Hexapeptide-8 for BlepharospasmTerminatedNCT01750346Phase 2
16Motor and Premotor Cortex Stimulation for Treatment of Secondary Focal Dystonia With Striato Palliadal Lesion : Evaluation of Safety and EffectivenessCompletedNCT00505323Phase 1
17Repetitive Transcranial Magnetic Stimulation for the Treatment of Focal Hand DystoniaCompletedNCT01884064Phase 1
18Magnetic Resonance (MR) Guided Functional Ultrasound-Neurosurgery for Movement DisordersCompletedNCT01698450Phase 1
19Survey of Sensory and Motor Tricks in Focal DystoniaCompletedNCT00054652
20Association Between Focal Dystonia and Complex Regional Pain SyndromeCompletedNCT00595439
21Sensory Training to Treat Focal DystoniaCompletedNCT00006336
22Transcranial Magnetic Stimulation and Electrical Stimulation of Nerves to Study Focal DystoniaCompletedNCT00050024
23EEG and EMG Studies of Hand DystoniaCompletedNCT00025701
24Role of Neurotransmission and Functional CNS Networks in Spasmodic DysphoniaCompletedNCT00713414
25Brain Changes in Patients With Focal Hand DystoniaCompletedNCT00306865
26Neurophysiology of Task-Specificity of Focal Hand DystoniaCompletedNCT00309010
27Brain Function in Focal DystoniaCompletedNCT00102999
28Movement-Related Brain Networks Involved in Hand DystoniaCompletedNCT00137384
29Transcranial Magnetic Stimulation (TMS) Studies of DystoniaCompletedNCT00017875
30Surround Inhibition in Patients With DystoniaCompletedNCT00029601
31fMRI Studies of Task Specificity in Focal Hand DystoniaCompletedNCT00310414
32Long-Term Motor Learning in Focal Hand DystoniaCompletedNCT00325091
33Movement Disorder Survey in East ChinaCompletedNCT01168388
34Neurophysiological Markers in Patients With Craniofacial Dystonia and Their RelativesCompletedNCT00082615
35Plasticity in Cervical DystoniaCompletedNCT00323765
36Cortical Excitability in Obsessive-Compulsive and Related DisordersCompletedNCT00029068
37Muscle Contraction in Patients With Focal Hand DystoniaCompletedNCT00376753
38MDs on Botox Utility (MOBILITY)CompletedNCT00535938
39Validating a New Writer s Cramp ScaleCompletedNCT01579266
40Identification of Optimal Stimulation Site for Cervical Dystonia Symptoms: An Exploratory StudyCompletedNCT01859247
41Functional Connectivity in Primary Focal DystoniaRecruitingNCT01761903
42Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal DystoniaRecruitingNCT02334683
43Depotentiation in People With Focal Hand DystoniaRecruitingNCT02106936
44Cholinergic Receptor Imaging in DystoniaRecruitingNCT02689466
45Somatosensory Processing in Focal Hand DystoniaRecruitingNCT00579033
46rTMS and Botulinum Toxin in Benign Essential BlepharospasmRecruitingNCT02370875
47rTMS and Botulinum Toxin in Primary Cervical DystoniaRecruitingNCT02542839
48Transcranial Magnetic Stimulation for Focal Hand DystoniaRecruitingNCT01792336
49Effect of Increasing Motor Cortex Inhibition on Task Specific DystoniaRecruitingNCT01823237
50ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement DisordersRecruitingNCT02252380

Search NIH Clinical Center for Focal Dystonia

Genetic Tests for Focal Dystonia

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Genetic tests related to Focal Dystonia:

id Genetic test Affiliating Genes
1 Focal Dystonia25

Anatomical Context for Focal Dystonia

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MalaCards organs/tissues related to Focal Dystonia:

34
Brain, Cortex, Spinal cord, Skin

Animal Models for Focal Dystonia or affiliated genes

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MGI Mouse Phenotypes related to Focal Dystonia:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053867.8CIZ1, DRD2, DRD5, GNAL, SGCE, TBP

Publications for Focal Dystonia

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Articles related to Focal Dystonia:

(show top 50)    (show all 207)
idTitleAuthorsYear
1
Lack of association between TOR1A and THAP1 mutations and sporadic adult-onset primary focal dystonia in a Chinese population. (26803725)
2016
2
Focal Dystonia in Hemiplegic Upper Limb: Favorable Effect of Cervical Microsurgical DREZotomy Involving the Ventral Horn - A Report of 3 Patients. (27225998)
2016
3
High prevalence of primary focal dystonia in the Faroe Islands. (26041438)
2015
4
Sensory-motor integration in focal dystonia. (26164472)
2015
5
Writer's cramp: is focal dystonia the best explanation? (23885297)
2013
6
Neurological picture. Isolated cerebellar hemiatrophy related with focal dystonia. (22842205)
2012
7
Neural network of primary focal dystonia by an anatomic likelihood estimation meta-analysis of gray matter abnormalities. (22349356)
2012
8
Deficient recognition of emotional prosody in primary focal dystonia. (20666836)
2011
9
Focal dystonia in musicians: phenomenology, pathophysiology, triggering factors, and treatment. (20795373)
2010
10
Functional evidence implicating a novel TOR1A mutation in idiopathic, late-onset focal dystonia. (19955557)
2010
11
THAP1: role in focal dystonia? (20083795)
2010
12
Results by motor cortex stimulation in treatment of focal dystonia, Parkinson's disease and post-ictal spasticity. The experience of the Italian Study Group of the Italian Neurosurgical Society. (18642628)
2008
13
Abnormal vibration-induced illusion of movement in idiopathic focal dystonia: an endophenotypic marker? (18044715)
2008
14
Clinical and genetic characterization of a large Dutch family with primary focal dystonia. (18823044)
2008
15
Botulinum neurotoxin type A free of complexing proteins (XEOMIN) in focal dystonia. (17385940)
2007
16
Morphometric changes of sensorimotor structures in focal dystonia. (17443700)
2007
17
Adult-onset lower extremity focal dystonia: case reports. (17559775)
2007
18
Kinesthesia is impaired in focal dystonia. (16482525)
2006
19
Unilateral Holmes tremor and focal dystonia after Gamma Knife surgery. (18503362)
2006
20
Muscle cramps associated with localized scleroderma skin lesions: focal dystonia, neuromyotonia, or nerve entrapment? (17143993)
2006
21
Abnormal co-contraction in yips-affected but not unaffected golfers: evidence for focal dystonia. (15911823)
2005
22
Focal dystonia is associated with a polymorphism of the dopamine D5 receptor gene. (14509667)
2004
23
Quantification of focal dystonia in pianists using scale analysis. (14978672)
2004
24
Focal dystonia caused by Mohr-Tranebjaerg syndrome with complete deletion of the DDP1 gene. (15037720)
2004
25
Musician's focal dystonia. (12852672)
2003
26
Focal dystonia: advances in brain imaging and understanding of fine motor control in musicians. (12945651)
2003
27
The effect of fatigue on abnormal vibration induced illusion of movement in idiopathic focal dystonia. (12876261)
2003
28
Candidate gene studies in focal dystonia. (14581671)
2003
29
Obsessive compulsive disorder among idiopathic focal dystonia patients: an epidemiological and family study. (12208643)
2002
30
Copper genes are not implicated in the pathogenesis of focal dystonia. (12221184)
2002
31
Familial focal dystonia. (12422077)
2002
32
Abnormalities of sensorimotor integration in focal dystonia: a transcranial magnetic stimulation study. (11222454)
2001
33
The GAG deletion of the DYT1 gene is infrequent in musicians with focal dystonia. (11087801)
2000
34
Movement-related electroencephalographic desynchronization in patients with hand cramps: evidence for motor cortical involvement in focal dystonia. (10762156)
2000
35
Abnormal perception of the tonic vibration reflex in idiopathic focal dystonia. (11054138)
2000
36
The metabolic topography of essential blepharospasm: a focal dystonia with general implications. (10980732)
2000
37
Assessment of postexcitatory inhibition in patients with focal dystonia. (10510687)
1999
38
An orthodontic appliance used in management of lingual focal dystonia. (10895671)
1999
39
Questionable role of adult-onset focal dystonia among sporadic dystonia patients. (9851449)
1998
40
Idiopathic focal dystonia: a disorder of muscle spindle afferent processing? (9448573)
1997
41
Does ulnar neuropathy predispose to focal dystonia? (7753123)
1995
42
Biomechanical abnormalities in musicians with occupational cramp/focal dystonia. (8124444)
1993
43
Focal dystonia secondary to cavernous angioma of the basal ganglia: case report and review of the literature. (1470322)
1992
44
Botulinum toxin treatment of cranial-cervical dystonia, spasmodic dysphonia, other focal dystonias and hemifacial spasm. (2213039)
1990
45
The "yips": a focal dystonia of golfers. (2915788)
1989
46
Hypothalamic dysregulation of immune responses in focal dystonia. (3630639)
1987
47
Focal dystonia and lacunar infarction of the basal ganglia: a case report. (6848097)
1983
48
Focal dystonia in association with cerebral infarction. (7175538)
1982
49
Writers' cramp-a focal dystonia. (7104663)
1982
50
Integrated EMG feedback in the management of spasmodic torticollis and focal dystonia: a prospective study of 80 patients. (1087448)
1976

Variations for Focal Dystonia

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Expression for genes affiliated with Focal Dystonia

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Search GEO for disease gene expression data for Focal Dystonia.

Pathways for genes affiliated with Focal Dystonia

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Pathways related to Focal Dystonia according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3DRD2, DRD5, GNAL

GO Terms for genes affiliated with Focal Dystonia

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Cellular components related to Focal Dystonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ciliary membraneGO:00601709.7DRD2, DRD5
2nonmotile primary ciliumGO:00315139.4DRD2, DRD5

Biological processes related to Focal Dystonia according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1chaperone-mediated protein transportGO:007232110.2TIMM8A, TOR1A
2regulation of dopamine uptake involved in synaptic transmissionGO:005158410.0DRD2, TOR1A
3adenylate cyclase-activating dopamine receptor signaling pathwayGO:00071919.9DRD5, GNAL
4phospholipase C-activating dopamine receptor signaling pathwayGO:00601589.9DRD2, DRD5
5synaptic transmission, dopaminergicGO:00019639.8DRD2, DRD5
6response to cocaineGO:00422209.8DRD2, DRD5
7negative regulation of blood pressureGO:00457769.8DRD2, DRD5
8adenylate cyclase-activating G-protein coupled receptor signaling pathwayGO:00071899.8DRD5, GNAL
9response to amphetamineGO:00019759.7DRD2, DRD5
10associative learningGO:00083069.7DRD2, DRD5
11activation of adenylate cyclase activityGO:00071909.6DRD5, GNAL

Molecular functions related to Focal Dystonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1dopamine bindingGO:00352409.7DRD2, DRD5
2dopamine neurotransmitter receptor activityGO:00049529.4DRD2, DRD5

Sources for Focal Dystonia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet