MCID: FCL005
MIFTS: 60

Focal Segmental Glomerulosclerosis malady

Categories: Genetic diseases, Rare diseases, Nephrological diseases, Neuronal diseases, Mental diseases

Aliases & Classifications for Focal Segmental Glomerulosclerosis

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Aliases & Descriptions for Focal Segmental Glomerulosclerosis:

Name: Focal Segmental Glomerulosclerosis 32 10 45 22 12
Fg Syndrome 10 68 45 23 12 65
Opitz-Kaveggia Syndrome 10 45 23 36
Glomerulosclerosis, Focal Segmental 47 36 24
Keller Syndrome 10 45 23
Fgs 10 45 23
Familial Idiopathic Steroid-Resistant Nephrotic Syndrome 45 51
Segmental Glomerulosclerosis 45 65
Focal Glomerulosclerosis 10 65
Fsgs 10 45
Fgs1 45 23
 
Mental Retardation, Large Head, Imperforate Anus, Congenital Hypotonia, and Partial Agenesis of the Corpus Callosum 23
Mental Retardation, Large Head, Imperforate Anus, Congenital Hypotonia, and Partial Agenesis of Corpus Callosum 45
Idiopathic Focal Segmental Glomerulosclerosis 22
Familial Focal Segmental Glomerulosclerosis 22
Familial Idiopathic Nephrotic Syndrome 51
Focal Sclerosis with Hyalinosis 45
Focal Glomerular Sclerosis 10
Glomerulosclerosis, Focal 45
Glomerulosclerosis Focal 47
Oks 23

Characteristics:

Orphanet epidemiological data:

51
familial idiopathic steroid-resistant nephrotic syndrome:
Inheritance: Autosomal dominant,Autosomal recessive; Age of onset: All ages

Classifications:

Orphanet: 51 
Rare renal diseases


External Ids:

Disease Ontology10 DOID:1312, DOID:14711
NCIt42 C37308
Orphanet51 656
ICD10 via Orphanet28 N04
UMLS65 C0017668, C0220769, C0333497

Summaries for Focal Segmental Glomerulosclerosis

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NIH Rare Diseases:45 Fg syndrome (fgs) is a genetic condition that affects many parts of the body and occurs almost exclusively in males. "fg" represents the surname initials of the first individuals diagnosed with the disorder. people with fg syndrome frequently have intellectual disability ranging from mild to severe, hypotonia, constipation and/or anal anomalies, a distinctive facial appearance, broad thumbs and great toes, a large head compared to body size (relative macrocephaly), and abnormalities of the corpus callosum. medical problems including heart defects, seizures, undescended testicle, and an inguinal hernia have also been reported in some affected individuals. researchers have identified five regions of the x chromosome that are linked to fg syndrome in affected families. mutations in the med12 gene appears to be the most common cause of this disorder, leading to fg syndrome 1. other genes involved with fg syndrome include flna (fgs2), cask (fgs4), upf3b (fgs6), and  brwd3 (fgs7). fgs is inherited in an x-linked recessive pattern. individualized early intervention and educational services are important so that each child can reach their fullest potential.  last updated: 3/16/2016

MalaCards based summary: Focal Segmental Glomerulosclerosis, also known as fg syndrome, is related to nephrotic syndrome, type 4 and chronic lymphocytic leukemia, and has symptoms including seizuresand constipation. An important gene associated with Focal Segmental Glomerulosclerosis is TRPC6 (Transient Receptor Potential Cation Channel Subfamily C Member 6), and among its related pathways are Nephrin interactions and Nephrin/Neph1 signaling in the kidney podocyte. The drug cyclosporine has been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and lung, and related mouse phenotypes are cardiovascular system and renal/urinary system.

Wikipedia:68 Focal segmental glomerulosclerosis (FSGS) is a cause of nephrotic syndrome in children and adolescents,... more...

Related Diseases for Focal Segmental Glomerulosclerosis

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Diseases in the Focal Segmental Glomerulosclerosis family:

Focal Segmental Glomerulosclerosis 8 Focal Segmental Glomerulosclerosis 9
Glomerulosclerosis, Focal Segmental, 4 Glomerulosclerosis, Focal Segmental, 3
Glomerulosclerosis, Focal Segmental, 7 Glomerulosclerosis, Focal Segmental, 2
Glomerulosclerosis, Focal Segmental, 5 Glomerulosclerosis, Focal Segmental, 6
Glomerulosclerosis, Focal Segmental, 1

Diseases related to Focal Segmental Glomerulosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 180)
idRelated DiseaseScoreTop Affiliating Genes
1nephrotic syndrome, type 430.4CD2AP, NPHS1, PAX2, WT1
2chronic lymphocytic leukemia29.1ACE, ALB, NPHS2
3antiphospholipid syndrome28.7ACE, ALB, NPHS1, NPHS2
4opitz-kaveggia syndrome12.6
5focal segmental glomerulosclerosis 812.5
6focal segmental glomerulosclerosis 912.4
7fg syndrome 212.2
8fg syndrome 412.2
9fg syndrome 312.0
10fg syndrome 512.0
11glomerulosclerosis, focal segmental, 311.9
12glomerulosclerosis, focal segmental, 211.9
13glomerulosclerosis, focal segmental, 511.9
14glomerulosclerosis, focal segmental, 611.9
15glomerulosclerosis, focal segmental, 111.8
16glomerulosclerosis, focal segmental, 411.8
17glomerulosclerosis, focal segmental, 711.8
18glomerulosclerosis11.3
19sporadic idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis11.2
20familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis11.2
21idiopathic steroid-sensitive nephrotic syndrome with focal segmental hyalinosis11.2
22c1q nephropathy10.7
23nephrotic syndrome10.6
24familial idiopathic steroid-resistant nephrotic syndrome with minimal changes10.6APOL1, NPHS2
25nephrogenic adenofibroma10.5PAX2, WT1
26autosomal recessive myogenic arthrogryposis multiplex congenita10.5CD2AP, NPHS1
27nephrotic syndrome, type 110.5
28cloverleaf skull-multiple congenital anomalies syndrome10.4NPHS1, PTPRO
29familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.4PTPRO, WT1
30coenzyme q10 deficiency, primary, 610.4
31muscular dystrophy-dystroglycanopathy , type a, 110.3CD2AP, NPHS2, PAX2
32gastroesophageal junction adenocarcinoma10.3PAX2, WT1
33nephrotic syndrome, type 210.3
34nephrotic syndrome, type 310.3
35nephrotic syndrome, type 910.3
36membranous nephropathy10.3
37lujan-fryns syndrome10.3
38glomerulonephritis10.3
39hepatitis10.3
40liver sarcoma10.3PAX2, WT1
41obesity10.2
42kidney disease10.2
43steroid-resistant nephrotic syndrome10.2
44endotheliitis10.2
45episodic ataxia10.2ALB, NPHS1
46pfeiffer syndrome type 310.2NPHS1, NPHS2, PTPRO
47breast pericanalicular fibroadenoma10.2PAX2, WT1
48nephrotic syndrome, type 5, with or without ocular abnormalities10.2
49nephrotic syndrome, type 610.2
50nephrotic syndrome, type 1010.2

Graphical network of the top 20 diseases related to Focal Segmental Glomerulosclerosis:



Diseases related to focal segmental glomerulosclerosis

Symptoms for Focal Segmental Glomerulosclerosis

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UMLS symptoms related to Focal Segmental Glomerulosclerosis:


seizures, constipation

Drugs & Therapeutics for Focal Segmental Glomerulosclerosis

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Drugs for Focal Segmental Glomerulosclerosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 116)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Valsartanapproved, investigationalPhase 4268137862-53-460846
Synonyms:
(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
(S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(s)-2-(n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)-3-methylbutanoic acid
137862-53-4
AC-4543
AC1L1U1M
AC1Q5QIK
Ambap137862-53-4
Aventis brand of valsartan
BIDD:GT0345
BRD-K45158365-001-02-3
BSPBio_003501
Bio-0796
C081489
C24H29N5O3
CEPA brand of valsartan
CGP 48933
CGP-48933
CHEBI:9927
CHEMBL1069
CID60846
CPD000466318
D00400
DB00177
Diovan
Diovan (TN)
Diovan, Valsartan
Esteve brand of valsartan
HMS1922L21
HMS2051L12
HMS2093K22
HSDB 7519
KBio2_002287
KBio2_004855
KBio2_007423
KBio3_003006
KBioGR_001078
KBioSS_002289
Kalpress
 
L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
LS-161334
Lacer brand of valsartan
MLS000759423
MLS001424088
Miten
MolPort-002-507-854
MolPort-003-666-608
N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-Pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-valeryl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)valine
Nisis
Nisis||
Novartis brand of valsartan
Provas
S1894_Selleck
SAM001246581
SMR000466318
SPBio_001260
SPECTRUM1505209
Sanol brand of valsartan
Schwarz brand of valsartan
Spectrum2_001120
Spectrum3_001831
Spectrum4_000749
Spectrum5_001582
Spectrum_001796
TL8000869
Tareg
UNII-80M03YXJ7I
Vals
Valsarran
Valsartan
Valsartan (JAN/USAN/INN)
Valsartan [USAN:INN]
valsartan
walsartan
|Tareg
2Angiotensin Receptor AntagonistsPhase 4, Phase 21039
3Angiotensin II Type 1 Receptor BlockersPhase 4, Phase 2949
4Antihypertensive AgentsPhase 4, Phase 23618
5beta-endorphinPhase 4, Phase 399
6Adrenocorticotropic HormonePhase 4, Phase 3133
7
Angiotensin IIPhase 4, Phase 2103368521-88-0, 11128-99-7172198, 65143
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
8AngiotensinogenPhase 4, Phase 21032
9Hormone AntagonistsPhase 4, Phase 3, Phase 210002
10Immunoglobulin APhase 4110
11Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 29988
12HormonesPhase 4, Phase 3, Phase 211748
13Melanocyte-Stimulating HormonesPhase 4, Phase 398
14
Mycophenolate mofetilapproved, investigationalPhase 3898128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate Mofetil
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
15
PrednisoloneapprovedPhase 3, Phase 2108250-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
Flo-pred
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
MLS001304083
 
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
Millipred
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Omnipred
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
16
Dexamethasoneapproved, investigationalPhase 3, Phase 2190950-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Baycadron
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
Dexameth
Dexamethansone
 
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone acetate
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone sodium phosphate
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamethsone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
Ozurdex
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
17
ChlorambucilapprovedPhase 352305-03-32708
Synonyms:
23125_FLUKA
305-03-3
4-(P-Bis(beta-chloroethyl)aminophenyl)butyric acid
4-(p-bis(β-chloroethyl)aminophenyl)butyric acid
4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid
AB00051938
AC1L1EAB
AC1Q75DO
AI3-26083
Ambochlorin
Amboclorin
BPBio1_001208
BRD-K29458283-001-05-9
BRN 0999011
BSPBio_001098
BSPBio_001971
C 0253
C0253_SIGMA
C14H19Cl2NO2
CAS-305-03-3
CB 1348
CB-1348
CB1348
CCRIS 126
CHEBI:28830
CHEMBL515
CHLORAMBUCIL
CID2708
CPD000058372
Cb l348
Chlocambucil
Chloorambucol
Chlorambucil (USP/INN)
Chlorambucil [INN:BAN]
Chlorambucilum
Chlorambucilum [INN-Latin]
Chloraminophen
Chloraminophene
Chlorbutin
Chlorbutine
Chlorbutinum
Chloroambucil
Chlorobutin
Chlorobutine
Clorambucile
Clorambucile [DCIT]
Clorambucilo
Clorambucilo [INN-Spanish]
D00266
D002699
DB00291
DivK1c_000688
EINECS 206-162-0
EU-0100227
Ecloril
Elcoril
Elcorin
FT-0083565
Glaxo Wellcome Brand of Chlorambucil
GlaxoSmithKline Brand of Chlorambucil
HMS1571G20
HMS1920M15
HMS2090M19
HMS2091A22
HMS502C10
HSDB 3026
IDI1_000688
KBio1_000688
KBio2_000558
 
KBio2_003126
KBio2_005694
KBio3_001191
KBioGR_000766
KBioSS_000558
LEUKERAN (TN)
LS-1158
Leuk ersan
Leukeran
Leukeran tablets
Leukersan
Leukoran
Linfolizin
Linfolysin
Lopac-C-0253
Lopac0_000227
Lympholysin
MLS000028443
MLS001076130
MolPort-000-152-694
N,N-Di-2-chloroethyl-gamma-P-aminophenylbutyric acid
N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid
NCGC00015199-01
NCGC00015199-02
NCGC00015199-03
NCGC00015199-07
NCGC00015199-14
NCGC00023250-00
NCGC00023250-03
NCGC00023250-04
NCGC00023250-05
NCGC00023250-06
NCGC00023250-07
NCGC00023250-08
NCGC00023250-09
NCGC00023250-10
NCI-C03485
NCI60_002639
NINDS_000688
NSC 3088
NSC-3088
NSC3088
Phenylbuttersaeure-lost
Phenylbuttersaeure-lost [German]
Phenylbutyric Acid Nitrogen Mustard
Phenylbutyric acid nitrogen mustard
Prestwick0_001079
Prestwick1_001079
Prestwick2_001079
Prestwick3_001079
RCRA waste no. U035
Rcra waste number U035
SAM002564202
SMR000058372
SPBio_000249
SPBio_002999
SPECTRUM1500171
ST50410766
Spectrum2_000065
Spectrum3_000336
Spectrum4_000273
Spectrum5_000677
Spectrum_000118
TL8002353
UNII-18D0SL7309
WLN: QV3R DN2G2G
Wellcome Brand of Chlorambucil
chlorambucil
gamma-[P-Di(2-chloroethyl)aminophenyl]butyric acid
γ-[p-di(2-chloroethyl)aminophenyl]butyric acid
18
rituximabapprovedPhase 3, Phase 21582174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
19
Mycophenolic acidapprovedPhase 389824280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
Melbex
 
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolic Acid
Mycophenolsaeure
Myfortic
20
Miconazoleapproved, investigationalPhase 3, Phase 2302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
21
MethylprednisoloneapprovedPhase 3, Phase 2108283-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
A-methapred
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Depo-medrol
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Solu-medrol
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
22Methylprednisolone acetatePhase 3, Phase 21082
23Alkylating AgentsPhase 3, Phase 1, Phase 23582
24Antibiotics, AntitubercularPhase 3, Phase 25971
25Antineoplastic Agents, AlkylatingPhase 3, Phase 1, Phase 23406
26Protective AgentsPhase 3, Phase 25651
27Prednisolone phosphatePhase 3, Phase 21082
28Protease InhibitorsPhase 3, Phase 24558
29Prednisolone hemisuccinatePhase 3, Phase 21082
30Prednisolone acetatePhase 3, Phase 21082
31Neuroprotective AgentsPhase 31376
32Methylprednisolone HemisuccinatePhase 3, Phase 21082
33Anti-Bacterial AgentsPhase 3, Phase 29140
34Antirheumatic AgentsPhase 3, Phase 2, Phase 18496
35BB 1101Phase 3, Phase 21909
36AntiemeticsPhase 3, Phase 23213
37Antineoplastic Agents, HormonalPhase 3, Phase 24256
38Anti-Inflammatory AgentsPhase 3, Phase 2, Phase 18478
39Peripheral Nervous System AgentsPhase 3, Phase 218510
40Antifungal AgentsPhase 3, Phase 23015
41Anti-Infective AgentsPhase 3, Phase 217220
42CyclosporinsPhase 3873
43Calcineurin InhibitorsPhase 3, Phase 21223
44HIV Protease InhibitorsPhase 3, Phase 24558
45Dermatologic AgentsPhase 34555
46Immunosuppressive AgentsPhase 3, Phase 2, Phase 110422
47glucocorticoidsPhase 3, Phase 23896
48Immunologic FactorsPhase 3, Phase 2, Phase 118483
49Gastrointestinal AgentsPhase 3, Phase 26401
50Dexamethasone 21-phosphatePhase 3, Phase 21909

Interventional clinical trials:

(show top 50)    (show all 56)
idNameStatusNCT IDPhase
1Idiopathic Focal Segmental Glomerulosclerosis (FSGS) and Treatment With ACTHCompletedNCT01155141Phase 4
2Treatment of Resistant Nephrotic Syndrome With ACTH Gel (ACTHAR)CompletedNCT01129284Phase 4
3Treatment of Proteinuria Due to Treatment Resistant or Treatment Intolerant Idiopathic FSGSRecruitingNCT02633046Phase 4
4Treating to Reduce Albuminuria and Normalize Hemodynamic Function in Focal ScLerosis With dApagliflozin Trial EffectsRecruitingNCT02585804Phase 4
5Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney DiseaseTerminatedNCT01129557Phase 4
6Focal Segmental Glomerulosclerosis Clinical Trial (FSGS-CT)CompletedNCT00135811Phase 3
7Mycophenolate Mofetil in Membranous Nephropathy and Focal SegmentalCompletedNCT00404833Phase 3
8Rituximab in Multirelapsing Minimal Change Disease (MCD) or Focal Segmental Glomerulosclerosis (FSGS)CompletedNCT00981838Phase 3
9Steroid Treatment for Kidney DiseaseCompletedNCT00065611Phase 3
10Efficacy of Rituximab For the Treatment of Calcineurin Inhibitors Dependent Nephrotic Syndrome During ChildhoodCompletedNCT01268033Phase 2, Phase 3
11Rituximab to Prevent Recurrence of ProteinuriaActive, not recruitingNCT01164098Phase 3
12Use of Acthar in Patients With FSGS That Will be Undergoing Renal TransplantationNot yet recruitingNCT02683889Phase 3
13Rituximab Treatment of Focal Segmental GlomerulosclerosisCompletedNCT00550342Phase 2
14Sirolimus for Focal Segmental GlomerulosclerosisCompletedNCT00040508Phase 2
15Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis)CompletedNCT00001959Phase 2
16Permeability Factor in Focal Segmental GlomerulosclerosisCompletedNCT00007475Phase 1, Phase 2
17Once-A-Month Steroid Treatment for Patients With Focal Segmental GlomerulosclerosisCompletedNCT00004990Phase 2
18A Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS)CompletedNCT01665391Phase 2
19Novel Therapies for Resistant FSGS (FONT II): Phase II Clinical TrialCompletedNCT00814255Phase 2
20Pilot Study to Evaluate the Safety and Efficacy of Abatacept in Adults and Children Over the Age of 6 With Excessive Loss of Protein in the Urine Due to Either Focal Segmental Glomerulosclerosis (FSGS) or Minimal Change Disease (MCD)RecruitingNCT02592798Phase 2
21Retinoids for Minimal Change Disease and Focal Segmental GlomerulosclerosisRecruitingNCT00098020Phase 1, Phase 2
22A Phase II, Repeat Dose, Proof of Mechanism Study of Losmapimod to Reduce Proteinuria in Patients With Focal Segmental Glomerulosclerosis (FSGS)Active, not recruitingNCT02000440Phase 2
23Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental GlomerulosclerosisActive, not recruitingNCT01613118Phase 2
24A Pilot Study to Assess the Efficacy of Rituximab Therapy in Treatment Resistant FSGSActive, not recruitingNCT01573533Phase 2
25Safety Study of GC1008 in Patients With Focal Segmental Glomerulosclerosis (FSGS) of Single Doses of GC1008 in Patients With Treatment Resistant Idiopathic FSGSCompletedNCT00464321Phase 1
26Total Lymphoid Irradiation (TLI) to Prevent Focal Segmental Glomerulosclerosis (FSGS)Recurrence in the Renal GraftCompletedNCT00353535Phase 1
27Pilot Studies of Novel Therapies to Treat Resistant Focal Segmental Glomerulosclerosis (FSGS)CompletedNCT00193648Phase 1
28Stem Cell Therapy for Patients With Focal Segmental GlomerulosclerosisRecruitingNCT02693366Phase 1
29Allogenic AD-MSC Transplantation in Idiopathic Nephrotic Syndrome (Focal Segmental Glomerulosclerosis)RecruitingNCT02382874Phase 1
30A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte DiseasesRecruitingNCT02639260Phase 1
31Safety and Pharmacokinetics of FG-3019 in Adolescents and Adults With Focal Segmental Glomerulosclerosis (FSGS)TerminatedNCT00782561Phase 1
32Effect of Oral Galactose on Focal Segmental Glomerulosclerosis (FSGS) Permeability FactorTerminatedNCT00816478Phase 1
33Effect of Galactose on Permeblity Factor in Patients With FSGS and CKD Stage 5WithdrawnNCT00816504Phase 1
34Prednisone Plus Tripterygium Wilfordii Treatment of Adult Patients With Idiopathic Focal Segmental GlomerulosclerosisCompletedNCT00801463
35Oral Galactose in Children With Steroid Resistant Nephrotic SyndromeCompletedNCT01113385
36Kidney Disease BiomarkersCompletedNCT00255398
37Evaluation of Albuminuria HIV-Infected PatientsCompletedNCT00524992
38Regional Citrate Anticoagulation in Plasma Exchange TreatmentCompletedNCT01370200
39The Effects of Helicobacter Pylori Eradication on Proteinuria in Patients With Membranous NephropathyCompletedNCT00983034
40Role of Donor Genetics and Recipient Genetics in Kidney Transplant OutcomesCompletedNCT01143532
41Lupus Nephritis Biomarker Study: Baseline Characteristics of PatientsCompletedNCT01470183
42Genetic Markers for Focal Segmental GlomerulosclerosisRecruitingNCT00001393
43Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in ChildrenRecruitingNCT02235857
44The Efficacy and Safety of Tacrolimus in Treated Refractory Focal Segmental GlomerulosclerosisRecruitingNCT01451489
45Nephrotic Syndrome Study NetworkRecruitingNCT01209000
46Genetic Causes of FSGS, Nephrotic Syndrome, or Kidney FailureRecruitingNCT02194582
47Pathogenesis of GlomerulosclerosisRecruitingNCT00001392
48Proteinuria in Pre and Post TransplantRecruitingNCT01094327
49A Prospective Controlled Study of Serum suPAR in the CsA-treated FSGS PatientsRecruitingNCT01468493
50INSIGHT (Insight Into Nephrotic Syndrome)RecruitingNCT01605266

Search NIH Clinical Center for Focal Segmental Glomerulosclerosis

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: opitz-kaveggia syndrome

Genetic Tests for Focal Segmental Glomerulosclerosis

About this section

Genetic tests related to Focal Segmental Glomerulosclerosis:

id Genetic test Affiliating Genes
1 Focal Segmental Glomerulosclerosis22 TRPC6

Anatomical Context for Focal Segmental Glomerulosclerosis

About this section

MalaCards organs/tissues related to Focal Segmental Glomerulosclerosis:

33
Kidney, Heart, Lung, Thyroid, Liver, Prostate, Endothelial

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Focal Segmental Glomerulosclerosis:
id TissueAnatomical CompartmentCell Relevance
1 KidneyPodocyte LayerPodocytes Potential therapeutic candidate, affected by disease

Animal Models for Focal Segmental Glomerulosclerosis or affiliated genes

About this section

MGI Mouse Phenotypes related to Focal Segmental Glomerulosclerosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053857.7ACE, ACTN4, CD2AP, MYO1E, NPHS2, PAX2
2MP:00053675.7ACE, ACTN4, ALB, CD2AP, LAMB2, MYO1E

Publications for Focal Segmental Glomerulosclerosis

About this section

Articles related to Focal Segmental Glomerulosclerosis:

(show top 50)    (show all 646)
idTitleAuthorsYear
1
An unusual case of focal segmental glomerulosclerosis presenting with retropharyngeal edema. (27133291)
2016
2
Treatment of Focal Segmental Glomerulosclerosis Recurrence in the Renal Allograft: A Report of Two Cases. (27099858)
2016
3
Rituximab for Recurrence of Primary Focal Segmental Glomerulosclerosis After Kidney Transplantation: Clinical Outcomes. (27043407)
2016
4
A possible influence of age on absorption and elimination of adalimumab in focal segmental glomerulosclerosis (FSGS). (26521258)
2015
5
Collagen (COL4A) mutations are the most frequent mutations underlying adult focal segmental glomerulosclerosis. (26346198)
2015
6
Glomerular endothelial cell injury and focal segmental glomerulosclerosis lesion in idiopathic membranous nephropathy. (25875837)
2015
7
Comparison of Glomerular Transcriptome Profiles of Adult-Onset Steroid Sensitive Focal Segmental Glomerulosclerosis and Minimal Change Disease. (26536600)
2015
8
Secondary focal segmental glomerulosclerosis in an adolescent born with a very low birth weight. (25274236)
2014
9
Lack of renoprotective effect of chronic intravenous Angiotensin-(1-7) or Angiotensin-(2-10) in a rat model of focal segmental glomerulosclerosis. (25337950)
2014
10
Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulosclerosis-associated glomerular injury. (24642466)
2014
11
Dynamic changes of urinary proteins in a focal segmental glomerulosclerosis rat model. (25061428)
2014
12
Mutational analysis of ACTN4, encoding I+-actinin 4, in patients with focal segmental glomerulosclerosis using HRM method. (23890478)
2013
13
Tacrolimus versus cyclophosphamide in steroid-dependent or steroid-resistant focal segmental glomerulosclerosis: a randomized controlled trial. (23343906)
2013
14
A review of the diagnosis and treatment of Ochratoxin A inhalational exposure associated with human illness and kidney disease including focal segmental glomerulosclerosis. (22253638)
2012
15
TRPC6 gene variants in Czech adult patients with focal segmental glomerulosclerosis and minimal change disease. (22980509)
2012
16
Treatment of recurrent focal segmental glomerulosclerosis in pediatric kidney transplant recipients: effect of rituximab. (21577271)
2011
17
Immunosuppressive treatment of focal segmental glomerulosclerosis: lessons from a randomized controlled trial. (21960168)
2011
18
Clinical course of primary focal segmental glomerulosclerosis (FSGS) in Turkish children: a report from the Turkish Pediatric Nephrology FSGS Study Group. (20718182)
2010
19
An unusual cause of focal segmental glomerulosclerosis: psoriasis vulgaris. (20486850)
2010
20
Atypical phenotype of type I Bartter syndrome accompanied by focal segmental glomerulosclerosis. (18830715)
2009
21
Prognostic value of clinical, laboratory, and morphological factors in patients with primary focal segmental glomerulosclerosis - distribution of pathological variants in the Croatian population. (19789521)
2009
22
Noonan syndrome: crossed fused ectopic kidneys and focal segmental glomerulosclerosis-a rare association. (19437094)
2009
23
Massive proteinuria and acute renal failure after oral bisphosphonate (alendronate) administration in a patient with focal segmental glomerulosclerosis. (18754075)
2009
24
Rituximab in minimal change nephropathy and focal segmental glomerulosclerosis: report of four cases and review of the literature. (19011266)
2008
25
Intramembranous microspherical structures in focal segmental glomerulosclerosis. (19002748)
2008
26
Focal segmental glomerulosclerosis and nephrotic syndrome in a child with embryonal rhabdomyosarcoma. (18175060)
2008
27
Review on diagnosis and treatment of focal segmental glomerulosclerosis. (18219061)
2008
28
Is focal segmental glomerulosclerosis increasing in patients with nephrotic syndrome? (17551756)
2007
29
Osteopontin as an injury marker expressing in epithelial hyperplasia lesions helpful in prognosis of focal segmental glomerulosclerosis. (17900509)
2007
30
Successful treatment of focal segmental glomerulosclerosis in association with mantle cell lymphoma. (17497453)
2007
31
Takayasu arteritis: association with focal segmental glomerulosclerosis. (16496079)
2007
32
NPHS2 variation in sporadic focal segmental glomerulosclerosis. (17942957)
2007
33
Educational feature on focal segmental glomerulosclerosis (FSGS): an introduction. (17106687)
2007
34
NPHS2 mutations in adult patients with primary focal segmental glomerulosclerosis. (16874699)
2006
35
Focal segmental glomerulosclerosis--does treatment work? (16785739)
2006
36
Computational simulation of renal biopsy accuracy in focal segmental glomerulosclerosis. (16773406)
2006
37
Reduced podocyte expression of alpha3beta1 integrins and podocyte depletion in patients with primary focal segmental glomerulosclerosis and chronic PAN-treated rats. (16887498)
2006
38
Collapsing and non-collapsing focal segmental glomerulosclerosis in kidney transplants. (16705026)
2006
39
Clinical and pathologic characteristics of focal segmental glomerulosclerosis pathologic variants. (16518352)
2006
40
Focal segmental glomerulosclerosis after membranous glomerulonephritis in remission: temporal diversity of glomerulopathy after bone marrow transplantation. (17020780)
2006
41
Hepatitis B infection as a possible cause of focal segmental glomerulosclerosis (FSGS). (16724663)
2006
42
Podocin-related mechanisms in posttransplant [corrected] recurrence of focal segmental glomerulosclerosis [corrected]. (17175312)
2006
43
The parietal epithelial cell is crucially involved in human idiopathic focal segmental glomerulosclerosis. (16164633)
2005
44
Coexistence of idiopathic membranous glomerulonephritis and idiopathic focal segmental glomerulosclerosis. (16370166)
2005
45
The focal segmental glomerulosclerosis permeability factor: biochemical characteristics and biological effects. (14709781)
2004
46
Apolipoprotein E in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis. (12631135)
2003
47
Secondary focal segmental glomerulosclerosis in non-obese patients with increased muscle mass. (14579937)
2003
48
Accumulation of cholesterol in the lesions of focal segmental glomerulosclerosis. (15012708)
2003
49
Mitochondrial cytopathy presenting with focal segmental glomerulosclerosis, hypoparathyroidism, sensorineural deafness, and progressive neurological disease. (11470934)
2001
50
Nephrotic syndrome associated with focal segmental glomerulosclerosis in a patient with systemic lupus erythematosus and membranous glomerulonephritis in remission (10561162)
1999

Variations for Focal Segmental Glomerulosclerosis

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Expression for genes affiliated with Focal Segmental Glomerulosclerosis

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Search GEO for disease gene expression data for Focal Segmental Glomerulosclerosis.

Pathways for genes affiliated with Focal Segmental Glomerulosclerosis

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Pathways related to Focal Segmental Glomerulosclerosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7ACTN4, CD2AP, NPHS1
29.4CD2AP, NPHS1, NPHS2, TRPC6
39.4ALB, PAX2, WT1

GO Terms for genes affiliated with Focal Segmental Glomerulosclerosis

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Cellular components related to Focal Segmental Glomerulosclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein complexGO:00432349.7ACTN4, CD2AP, NPHS2

Biological processes related to Focal Segmental Glomerulosclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glomerulus developmentGO:003283510.0PTPRO, WT1
2camera-type eye developmentGO:00430109.9PAX2, WT1
3metanephric glomerular visceral epithelial cell developmentGO:00722499.8LAMB2, NPHS2
4metanephric mesenchyme developmentGO:00720759.8PAX2, WT1
5negative regulation of programmed cell deathGO:00430699.8ALB, PAX2
6metanephric epithelium developmentGO:00722079.6PAX2, WT1

Molecular functions related to Focal Segmental Glomerulosclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1actin bindingGO:00037799.0ANLN, PLEKHH2, SYNPO

Sources for Focal Segmental Glomerulosclerosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet