FGS
MCID: FCL005
MIFTS: 60

Focal Segmental Glomerulosclerosis (FGS) malady

Categories: Genetic diseases, Rare diseases, Nephrological diseases, Neuronal diseases, Mental diseases

Aliases & Classifications for Focal Segmental Glomerulosclerosis

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Aliases & Descriptions for Focal Segmental Glomerulosclerosis:

Name: Focal Segmental Glomerulosclerosis 35 11 48 24 27 13
Fg Syndrome 11 71 48 25 13 68
Opitz-Kaveggia Syndrome 11 48 25
Keller Syndrome 11 48 25
Fgs 11 48 25
Familial Idiopathic Steroid-Resistant Nephrotic Syndrome 48 54
Familial Idiopathic Nephrotic Syndrome 48 54
Glomerulosclerosis, Focal Segmental 50 39
Segmental Glomerulosclerosis 48 68
Focal Glomerulosclerosis 11 68
Fgs1 48 25
 
Fsgs 11 48
Mental Retardation, Large Head, Imperforate Anus, Congenital Hypotonia, and Partial Agenesis of the Corpus Callosum 25
Mental Retardation, Large Head, Imperforate Anus, Congenital Hypotonia, and Partial Agenesis of Corpus Callosum 48
Focal Segmental Glomerulosclerosis, Not Otherwise Specified 68
Idiopathic Focal Segmental Glomerulosclerosis 24
Familial Focal Segmental Glomerulosclerosis 24
Focal Sclerosis with Hyalinosis 48
Focal Glomerular Sclerosis 11
Glomerulosclerosis, Focal 48
Glomerulosclerosis Focal 50
Oks 25

Characteristics:

Orphanet epidemiological data:

54
familial idiopathic steroid-resistant nephrotic syndrome:
Inheritance: Autosomal dominant,Autosomal recessive; Age of onset: All ages

Classifications:

Orphanet: 54 
Rare renal diseases


External Ids:

Disease Ontology11 DOID:1312, DOID:14711
NCIt45 C37308
Orphanet54 ORPHA656
ICD10 via Orphanet31 N04.1, N04.3, N04.8

Summaries for Focal Segmental Glomerulosclerosis

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NIH Rare Diseases:48 Fg syndrome (fgs) is a genetic condition that affects many parts of the body and occurs almost exclusively in males. "fg" represents the surname initials of the first individuals diagnosed with the disorder. people with fg syndrome frequently have intellectual disability ranging from mild to severe, hypotonia, constipation and/or anal anomalies, a distinctive facial appearance, broad thumbs and great toes, a large head compared to body size (relative macrocephaly), and abnormalities of the corpus callosum. medical problems including heart defects, seizures, undescended testicle, and an inguinal hernia have also been reported in some affected individuals. researchers have identified five regions of the x chromosome that are linked to fg syndrome in affected families. mutations in the med12 gene appears to be the most common cause of this disorder, leading to fg syndrome 1. other genes involved with fg syndrome include flna (fgs2), cask (fgs4), upf3b (fgs6), and  brwd3 (fgs7). fgs is inherited in an x-linked recessive pattern. individualized early intervention and educational services are important so that each child can reach their fullest potential.  last updated: 3/16/2016

MalaCards based summary: Focal Segmental Glomerulosclerosis, also known as fg syndrome, is related to fg syndrome 5 and frasier syndrome, and has symptoms including constipation and seizures. An important gene associated with Focal Segmental Glomerulosclerosis is TRPC6 (Transient Receptor Potential Cation Channel Subfamily C Member 6), and among its related pathways are Nephrin interactions and Nephrin/Neph1 signaling in the kidney podocyte. The drug cyclosporine has been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and endothelial, and related mouse phenotypes are vision/eye and cardiovascular system.

Wikipedia:71 Focal segmental glomerulosclerosis (FSGS) is a cause of nephrotic syndrome in children and adolescents,... more...

Related Diseases for Focal Segmental Glomerulosclerosis

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Diseases in the Focal Segmental Glomerulosclerosis family:

Focal Segmental Glomerulosclerosis 8 Focal Segmental Glomerulosclerosis 9
Glomerulosclerosis, Focal Segmental, 4 Glomerulosclerosis, Focal Segmental, 3
Glomerulosclerosis, Focal Segmental, 7 Glomerulosclerosis, Focal Segmental, 2
Glomerulosclerosis, Focal Segmental, 5 Glomerulosclerosis, Focal Segmental, 6
Glomerulosclerosis, Focal Segmental, 1

Diseases related to Focal Segmental Glomerulosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 170)
idRelated DiseaseScoreTop Affiliating Genes
1fg syndrome 532.6COL4A3, MYH9, MYO1E
2frasier syndrome29.5CD2AP, NPHS1, NPHS2, PAX2, WT1
3familial nephrotic syndrome29.3MYH9, NPHS1, NPHS2, WT1
4focal segmental glomerulosclerosis 812.5
5focal segmental glomerulosclerosis 912.5
6fg syndrome 412.2
7fg syndrome 212.2
8glomerulosclerosis, focal segmental, 112.0
9glomerulosclerosis, focal segmental, 712.0
10glomerulosclerosis, focal segmental, 212.0
11glomerulosclerosis, focal segmental, 512.0
12glomerulosclerosis, focal segmental, 612.0
13glomerulosclerosis, focal segmental, 412.0
14glomerulosclerosis, focal segmental, 312.0
15opitz-kaveggia syndrome11.9
16fg syndrome 311.9
17c1q nephropathy11.5
18nephrotic syndrome, type 111.3
19coenzyme q10 deficiency, primary, 611.3
20nephrotic syndrome, type 211.2
21nephrotic syndrome, type 311.2
22nephrotic syndrome, type 411.2
23nephrotic syndrome, type 911.2
24sporadic idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis11.1
25familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis11.1
26idiopathic steroid-sensitive nephrotic syndrome with focal segmental hyalinosis11.1
27nephrotic syndrome, type 5, with or without ocular abnormalities11.0
28nephrotic syndrome, type 611.0
29nephrotic syndrome, type 1011.0
30nephrotic syndrome type 1111.0
31nephrotic syndrome type 1211.0
32nephrotic syndrome type 1311.0
33x-linked intellectual disability with or without nystagmus11.0
34nephrotic syndrome, idiopathic, steroid-resistant10.9
35vaccinia10.8
36cask-related disorders10.8
37syndromic x-linked intellectual disability 1410.8
38nephrotic syndrome10.5
39mucinous adenofibroma10.2PAX2, WT1
40membranous nephropathy10.2
41hepatitis10.2
42glomerulonephritis10.2
43kidney disease10.2
44congenital bilateral megacalycosis10.1NPHS1, PTPRO
45muscular dystrophy-dystroglycanopathy , type b, 110.1CD2AP, NPHS2, PAX2
46sick sinus syndrome 310.1CD2AP, NPHS1, NPHS2
47cholangitis, primary sclerosing10.1LAMB2, NPHS2
48obesity10.1
49endotheliitis10.1
50hypertrichosis of eyelid10.1NPHS1, NPHS2, SYNPO

Graphical network of the top 20 diseases related to Focal Segmental Glomerulosclerosis:



Diseases related to focal segmental glomerulosclerosis

Symptoms & Phenotypes for Focal Segmental Glomerulosclerosis

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UMLS symptoms related to Focal Segmental Glomerulosclerosis:


constipation, seizures

MGI Mouse Phenotypes related to Focal Segmental Glomerulosclerosis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053917.7ACTN4, COL4A3, CRB2, LAMB2, MYH9, PAX2
2MP:00053857.6ACTN4, CD2AP, COL4A3, CRB2, MYH9, MYO1E
3MP:00107687.3ACTN4, CD2AP, COL4A3, CRB2, LAMB2, MYH9
4MP:00053677.1ACTN4, CD2AP, COL4A3, LAMB2, MYH9, MYO1E

Drugs & Therapeutics for Focal Segmental Glomerulosclerosis

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Drugs for Focal Segmental Glomerulosclerosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 126)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Valsartanapproved, investigationalPhase 4295137862-53-460846
Synonyms:
(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
(S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(s)-2-(n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)-3-methylbutanoic acid
137862-53-4
AC-4543
AC1L1U1M
AC1Q5QIK
Ambap137862-53-4
Aventis brand of valsartan
BIDD:GT0345
BRD-K45158365-001-02-3
BSPBio_003501
Bio-0796
C081489
C24H29N5O3
CEPA brand of valsartan
CGP 48933
CGP-48933
CHEBI:9927
CHEMBL1069
CID60846
CPD000466318
D00400
DB00177
Diovan
Diovan (TN)
Diovan, Valsartan
Esteve brand of valsartan
HMS1922L21
HMS2051L12
HMS2093K22
HSDB 7519
KBio2_002287
KBio2_004855
KBio2_007423
KBio3_003006
KBioGR_001078
KBioSS_002289
 
Kalpress
L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
LS-161334
Lacer brand of valsartan
MLS000759423
MLS001424088
Miten
MolPort-002-507-854
MolPort-003-666-608
N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-valeryl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)valine
Nisis
Nisis||
Novartis brand of valsartan
Provas
S1894_Selleck
SAM001246581
SMR000466318
SPBio_001260
SPECTRUM1505209
Sanol brand of valsartan
Schwarz brand of valsartan
Spectrum2_001120
Spectrum3_001831
Spectrum4_000749
Spectrum5_001582
Spectrum_001796
TL8000869
Tareg
UNII-80M03YXJ7I
Vals
Valsarran
Valsartan (JAN/USAN/INN)
Valsartan [USAN:INN]
valsartan
walsartan
|Tareg
2HormonesPhase 4, Phase 3, Phase 214415
3Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 213168
4Hormone AntagonistsPhase 4, Phase 3, Phase 213180
5Antihypertensive AgentsPhase 4, Phase 24207
6beta-endorphinPhase 4, Phase 3140
7Adrenocorticotropic HormonePhase 4, Phase 3164
8AngiotensinogenPhase 4, Phase 21177
9Angiotensin Receptor AntagonistsPhase 4, Phase 21191
10Immunoglobulin APhase 4120
11
Angiotensin IIPhase 4, Phase 2117868521-88-0, 11128-99-765143, 172198
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
12Melanocyte-Stimulating HormonesPhase 4, Phase 3139
13Angiotensin II Type 1 Receptor BlockersPhase 4, Phase 21091
14
Mycophenolic acidapprovedPhase 3, Phase 295224280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
15
Mycophenolate mofetilapproved, investigationalPhase 3, Phase 2952128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
16
Cyclosporineapproved, investigational, vet_approvedPhase 392279217-60-0, 59865-13-35284373, 6435893
Synonyms:
1c5f
1cyn
30024_FLUKA
30024_SIGMA
59865-13-3
79217-60-0
AC1L1EQW
AC1NQXJE
AC1NR4C4
AC1NUQK3
AC1NUZNC
AC1O5KOG
AC1Q2UDG
Ambap59865-13-3
Ambotz59865-13-3
Antibiotic S 7481F1
BMT-ABA-SAR-MLE-VAL-MLE-ALA-ALA-MLE-MLE-MVA
BMT-ABA-SAR-MLE-VAL-MLE-ALA-DAL-MLE-MLE-MVA
BPBio1_000496
BRD-A64290322-001-01-6
BRD-A69815203-001-04-3
BRD-K13533483-001-03-0
BSPBio_000450
BSPBio_001596
BSPBio_003186
C 3662
C05086
C1832_SIGMA
C3662_SIGMA
C62H111N11O12
CB-01-09 MMX
CHEBI:106343
CHEBI:328305
CHEBI:4031
CHEMBL160
CHEMBL386389
CHEMBL532318
CID2909
CID5280754
CID5284373
CID5458585
CID5497195
CID6435893
CSA
CYCLOSPORIN A (SEE ALSO TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A))
CYCLOSPORIN A, USP
Ciclosporin
Ciclosporin (JP15)
Ciclosporina
Ciclosporine
Ciclosporinum
Cipol N
Cipol-N
Consupren
Consupren S
CsA
CsA & IFN.alpha.
CyA
Cyclokat
Cyclosporin
Cyclosporin A
Cyclosporin A & IFN.alpha.
Cyclosporin A Implant
Cyclosporin A, Tolypocladium inflatum
Cyclosporine (USP)
Cyclosporine A
Cyclosporine [USAN]
D00184
DE-076
DivK1c_000871
EU-0100242
Equoral
GNF-Pf-2808
Gengraf
Gengraf (TN)
HMS1569G12
HMS1791P18
HMS1921L20
HMS1989P18
HMS2089A09
HMS2092F06
HMS502L13
Helv Chim Acta 60: 1568 (1977)
 
I06-0379
I06-0966
IDI1_000871
KBio1_000871
KBio2_000780
KBio2_003348
KBio2_005916
KBio3_002686
KBioGR_001898
KBioSS_000780
LMPK14000003
LS-257
LS-58836
Lopac0_000242
MLS000028376
MLS001333756
MLS002153454
MLS002207033
Mitogard
Modusik-A
MolPort-000-760-988
MolPort-005-934-008
MolPort-006-705-994
NCGC00093704-01
NCGC00093704-02
NCGC00093704-03
NCGC00093704-04
NCGC00093704-05
NCGC00093704-06
NCGC00093704-07
NCGC00093704-08
NCGC00164258-01
NCGC00164258-02
NINDS_000871
NSC290193
Neoplanta
Neoral
Neoral (TN)
NeuroSTAT
Nova-22007
OL 27-400
OL-27400
OLO-400
Papilock
Prestwick2_000435
Prestwick3_000435
Prestwick_731
Pulminiq
Ramihyphin A
Restasis
Restasis (TN)
S-Neoral
S1514_Selleck
SDZ-OXL 400
SMR000058578
SPBio_001467
SPECTRUM1502202
ST-603
Sandimmun
Sandimmun Neoral
Sandimmune
Sandimmune (TN)
Sandimmune, Gengraf, Restasis, Atopica, Sangcya, Cyclosporine
Sang-2000
Sang-35
SangCyA
Sangcya
Sigmasporin
Sigmasporin Microoral
Spectrum2_001484
Spectrum3_001593
Spectrum4_001279
Spectrum5_001628
Spectrum_000300
TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A)
Vekacia
Zyclorin
cyclophorine
cyclosporin A
cyclosporine
from Tolypocladium inflatum (Trichoderma polysporin)
nchembio.184-comp6
nchembio.301-comp5
nchembio.342-comp1
17
Dexamethasoneapproved, investigational, vet_approvedPhase 3, Phase 2217150-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
18
Miconazoleapproved, investigational, vet_approvedPhase 3, Phase 2370622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
19
Prednisoloneapproved, vet_approvedPhase 3, Phase 2119350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
20
ChlorambucilapprovedPhase 354305-03-32708
Synonyms:
23125_FLUKA
305-03-3
4-(P-Bis(beta-chloroethyl)aminophenyl)butyric acid
4-(p-bis(β-chloroethyl)aminophenyl)butyric acid
4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid
AB00051938
AC1L1EAB
AC1Q75DO
AI3-26083
Ambochlorin
Amboclorin
BPBio1_001208
BRD-K29458283-001-05-9
BRN 0999011
BSPBio_001098
BSPBio_001971
C 0253
C0253_SIGMA
C14H19Cl2NO2
CAS-305-03-3
CB 1348
CB-1348
CB1348
CCRIS 126
CHEBI:28830
CHEMBL515
CHLORAMBUCIL
CID2708
CPD000058372
Cb l348
Chlocambucil
Chloorambucol
Chlorambucil (USP/INN)
Chlorambucil [INN:BAN]
Chlorambucilum
Chlorambucilum [INN-Latin]
Chloraminophen
Chloraminophene
Chlorbutin
Chlorbutine
Chlorbutinum
Chloroambucil
Chlorobutin
Chlorobutine
Clorambucile
Clorambucile [DCIT]
Clorambucilo
Clorambucilo [INN-Spanish]
D00266
D002699
DB00291
DivK1c_000688
EINECS 206-162-0
EU-0100227
Ecloril
Elcoril
Elcorin
FT-0083565
Glaxo Wellcome Brand of Chlorambucil
GlaxoSmithKline Brand of Chlorambucil
HMS1571G20
HMS1920M15
HMS2090M19
HMS2091A22
HMS502C10
HSDB 3026
IDI1_000688
KBio1_000688
KBio2_000558
KBio2_003126
 
KBio2_005694
KBio3_001191
KBioGR_000766
KBioSS_000558
LEUKERAN (TN)
LS-1158
Leuk ersan
Leukeran
Leukeran Tablets
Leukeran tablets
Leukersan
Leukoran
Linfolizin
Linfolysin
Lopac-C-0253
Lopac0_000227
Lympholysin
MLS000028443
MLS001076130
MolPort-000-152-694
N,N-Di-2-chloroethyl-gamma-P-aminophenylbutyric acid
N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid
NCGC00015199-01
NCGC00015199-02
NCGC00015199-03
NCGC00015199-07
NCGC00015199-14
NCGC00023250-00
NCGC00023250-03
NCGC00023250-04
NCGC00023250-05
NCGC00023250-06
NCGC00023250-07
NCGC00023250-08
NCGC00023250-09
NCGC00023250-10
NCI-C03485
NCI60_002639
NINDS_000688
NSC 3088
NSC-3088
NSC3088
Pepstatin
Phenylbuttersaeure-lost
Phenylbuttersaeure-lost [German]
Phenylbutyric Acid Nitrogen Mustard
Phenylbutyric acid nitrogen mustard
Prestwick0_001079
Prestwick1_001079
Prestwick2_001079
Prestwick3_001079
RCRA waste no. U035
Rcra waste number U035
SAM002564202
SMR000058372
SPBio_000249
SPBio_002999
SPECTRUM1500171
ST50410766
Spectrum2_000065
Spectrum3_000336
Spectrum4_000273
Spectrum5_000677
Spectrum_000118
TL8002353
UNII-18D0SL7309
WLN: QV3R DN2G2G
Wellcome Brand of Chlorambucil
chlorambucil
gamma-[P-Di(2-chloroethyl)aminophenyl]butyric acid
γ-[p-di(2-chloroethyl)aminophenyl]butyric acid
21
Methylprednisoloneapproved, vet_approvedPhase 3, Phase 2119383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
22
rituximabapprovedPhase 3, Phase 21692174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
23
Valproic Acidapproved, investigationalPhase 2, Phase 332799-66-13121
Synonyms:
(N-C3H7)2CHCOOH
(S)-2-propyl-4-pentanoate
(S)-2-propyl-4-pentanoic acid
2 PP (base)
2-N-Propyl-N-valeric acid
2-Propyl-Pentanoate
2-Propyl-Pentanoic acid
2-Propylpentanoate
2-Propylpentanoic Acid
2-Propylpentanoic acid
2-Propylvaleric Acid
2-Propylvaleric acid
2-n-Propyl-n-valeric acid
2-n-propyl-n-valeric acid
2-propyl-pentanoic acid
2-propylvaleric acid
4-Heptanecarboxylic acid
4-heptanecarboxylic acid
76584-70-8 (hydrochloride salt (2:1))
99-66-1
AC1L1F7T
AC1Q2ULA
AI3-10500
APO-divalproex
Abbott 44090
Acide valproique
Acide valproique [INN-French]
Acide valproique [inn-french]
Acido valproico
Acido valproico [INN-Spanish]
Acido valproico [inn-spanish]
Acidum valproicum
Acidum valproicum [INN-Latin]
Acidum valproicum [inn-latin]
Alti-Valproic
Alti-valproic
Apo-valproic
Apo-valproic syrup
Avugane
BIDD:GT0858
BRN 1750447
Baceca
C07185
CHEBI:39867
CHEMBL109
CID3121
CPD000499581
Convulex
Convulsofin
D00399
DB00313
DOM-divalproex
DOM-valproic
DOM-valproic acid E.C.
DPA
Delepsine
Depacon
Depakene
Depakene (TN)
Depakin
Depakin chrono
Depakine
Depakine chrono
Depakote
Depakote (TM)
Deproic
Di-N-propylacetic acid
Di-N-propylessigsaure
Di-N-propylessigsaure [german]
Di-n-propylacetic acid
Di-n-propylessigsaeure
Di-n-propylessigsaure
Di-n-propylessigsaure [German]
Di-n-propylessigsäure
Dipropyl Acetate
Dipropylacetate
Dipropylacetic acid
DivK1c_000273
Divalproex
Dom-Valproic
Dom-valproate
Dom-valproic acid
Dom-valproic acid syrup
EINECS 202-777-3
Epiject I.V.
Epilex
Epilim
Epival
Epival er
Ergenyl
G2M-777
Gen-divalproex
HMS2089J06
HSDB 3582
I04-0211
InChI=1/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
KBio1_000273
KBio2_001001
KBio2_002277
KBio2_003569
KBio2_004845
 
KBio2_006137
KBio2_007413
KBio3_002626
KBio3_002757
KBioGR_000871
KBioGR_002277
KBioSS_001001
KBioSS_002278
Kyselina 2-propylvalerova
Kyselina 2-propylvalerova [Czech]
LS-161170
LS-2068
MLS001076682
MLS001335927
MLS001335928
MLS002415770
Med Valproic
Med valproic
MolPort-001-791-895
Mylproin
Myproate
Myproic Acid
Myproic acid
N-DPA
N-Dipropylacetic acid
NCGC00091149-01
NCGC00091149-02
NCGC00091149-03
NCGC00091149-04
NINDS_000273
NSC 93819
NSC93819
Novo-Valproic
Novo-Valproic - ECC
Novo-divalproex
Novo-valproic
Novo-valproic soft gel cap
Nu-Valproic
Nu-valproic
P0823
P6273_SIGMA
PEAC
PHL-valproate
PHL-valproic acid
PHL-valproic acid E.C.
PMS-Divalproex
PMS-Valproic Acid
PMS-valproate
PMS-valproic acid
PMS-valproic acid E.C.
Penta-Valproic
Penta-valproic
Propylvaleric acid
Ratio-Valproic - ECC
S(-)-4-En-valproate
S(-)-4-En-valproic acid
S-2-N-Propyl-4-pentenoate
S-2-N-Propyl-4-pentenoic acid
SAM002564230
SBB065764
SMR000499581
SPBio_000912
Sandoz valproic
Savicol
Semisodium Valproate
Sodium hydrogen divalproate
Spectrum2_000946
Spectrum3_001733
Spectrum4_000376
Spectrum_000521
Sprinkle
Stavzor
UNII-614OI1Z5WI
VALPROIC ACID
VPA
Valcote
Valparin
Valproate
Valproate semisodique [French]
Valproate semisodium
Valproato semisodico [Spanish]
Valproatum seminatricum [Latin]
Valproic Acid, Sodium Salt (2:1)
Valproic acid
Valproic acid (USP)
Valproic acid USP
Valproic acid USP24
Valproic acid [USAN:INN:BAN]
Valproic acid [usan:ban:inn]
Valproinsaeure
Valproinsäure
Vupral
WLN: QVY3 & 3
acide valproïque
acidum valproicum
di-n-propylacetic acid
n-DPA
n-Dipropylacetic acid
nchembio.79-comp4
nchembio815-comp21
valproate
valproic acid
ácido valproico
24glucocorticoidsPhase 3, Phase 25103
25Immunosuppressive AgentsPhase 3, Phase 2, Phase 113086
26Antineoplastic Agents, HormonalPhase 3, Phase 25592
27Anti-Inflammatory AgentsPhase 3, Phase 2, Phase 110729
28Calcineurin InhibitorsPhase 3, Phase 21622
29Methylprednisolone acetatePhase 3, Phase 21193
30Antineoplastic Agents, AlkylatingPhase 3, Phase 1, Phase 24603
31Methylprednisolone HemisuccinatePhase 3, Phase 21193
32Prednisolone phosphatePhase 3, Phase 21193
33Prednisolone acetatePhase 3, Phase 21193
34Prednisolone hemisuccinatePhase 3, Phase 21193
35Neuroprotective AgentsPhase 31716
36Protective AgentsPhase 3, Phase 27443
37
protease inhibitorsPhase 3, Phase 25471
Synonyms:
 
protease inhibitors
38Autonomic AgentsPhase 3, Phase 210150
39BB 1101Phase 3, Phase 22171
40Antirheumatic AgentsPhase 3, Phase 2, Phase 110956
41Anti-Infective AgentsPhase 3, Phase 222062
42Antifungal AgentsPhase 3, Phase 23696
43Antibiotics, AntitubercularPhase 3, Phase 27180
44Dermatologic AgentsPhase 35806
45Dexamethasone 21-phosphatePhase 3, Phase 22171
46Alkylating AgentsPhase 3, Phase 1, Phase 24827
47Anti-Bacterial AgentsPhase 3, Phase 211226
48AntiemeticsPhase 3, Phase 24022
49Peripheral Nervous System AgentsPhase 3, Phase 223689
50Dexamethasone acetatePhase 3, Phase 221711177-87-3

Interventional clinical trials:

(show top 50)    (show all 60)
idNameStatusNCT IDPhase
1Idiopathic Focal Segmental Glomerulosclerosis (FSGS) and Treatment With ACTHCompletedNCT01155141Phase 4
2Treatment of Resistant Nephrotic Syndrome With ACTH Gel (ACTHAR)CompletedNCT01129284Phase 4
3Treatment of Proteinuria Due to Treatment Resistant or Treatment Intolerant Idiopathic FSGSRecruitingNCT02633046Phase 4
4Treating to Reduce Albuminuria and Normalize Hemodynamic Function in Focal ScLerosis With dApagliflozin Trial EffectsRecruitingNCT02585804Phase 4
5Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney DiseaseTerminatedNCT01129557Phase 4
6Focal Segmental Glomerulosclerosis Clinical Trial (FSGS-CT)CompletedNCT00135811Phase 3
7Mycophenolate Mofetil in Membranous Nephropathy and Focal SegmentalCompletedNCT00404833Phase 3
8Rituximab in Multirelapsing Minimal Change Disease (MCD) or Focal Segmental Glomerulosclerosis (FSGS)CompletedNCT00981838Phase 3
9Steroid Treatment for Kidney DiseaseCompletedNCT00065611Phase 3
10Efficacy of Rituximab For the Treatment of Calcineurin Inhibitors Dependent Nephrotic Syndrome During ChildhoodCompletedNCT01268033Phase 2, Phase 3
11Rituximab to Prevent Recurrence of ProteinuriaCompletedNCT01164098Phase 3
12Use of Acthar in Patients With FSGS That Will be Undergoing Renal TransplantationRecruitingNCT02683889Phase 3
13Valproic Acid for Idiopathic Nephrotic SyndromeNot yet recruitingNCT02896270Phase 2, Phase 3
14Rituximab Treatment of Focal Segmental GlomerulosclerosisCompletedNCT00550342Phase 2
15Permeability Factor in Focal Segmental GlomerulosclerosisCompletedNCT00007475Phase 1, Phase 2
16Sirolimus for Focal Segmental GlomerulosclerosisCompletedNCT00040508Phase 2
17A Phase II, Repeat Dose, Proof of Mechanism Study of Losmapimod to Reduce Proteinuria in Patients With Focal Segmental Glomerulosclerosis (FSGS)CompletedNCT02000440Phase 2
18A Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS)CompletedNCT01665391Phase 2
19Novel Therapies for Resistant FSGS (FONTII): Phase II Clinical TrialCompletedNCT00814255Phase 2
20Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis)CompletedNCT00001959Phase 2
21Once-A-Month Steroid Treatment for Patients With Focal Segmental GlomerulosclerosisCompletedNCT00004990Phase 2
22Retinoids for Minimal Change Disease and Focal Segmental GlomerulosclerosisCompletedNCT00098020Phase 1, Phase 2
23Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant RecipientsRecruitingNCT02921789Phase 2
24A Pilot Study to Assess the Efficacy of Rituximab Therapy in Treatment Resistant FSGSRecruitingNCT01573533Phase 2
25Pilot Study to Evaluate the Safety and Efficacy of Abatacept in Adults and Children 6 Years and Older With Excessive Loss of Protein in the Urine Due to Either Focal Segmental Glomerulosclerosis (FSGS) or Minimal Change Disease (MCD)RecruitingNCT02592798Phase 2
26Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental GlomerulosclerosisActive, not recruitingNCT01613118Phase 2
27Safety Study of GC1008 in Patients With Focal Segmental Glomerulosclerosis (FSGS) of Single Doses of GC1008 in Patients With Treatment Resistant Idiopathic FSGSCompletedNCT00464321Phase 1
28Total Lymphoid Irradiation (TLI) to Prevent Focal Segmental Glomerulosclerosis (FSGS)Recurrence in the Renal GraftCompletedNCT00353535Phase 1
29Pilot Studies of Novel Therapies to Treat Resistant Focal Segmental Glomerulosclerosis (FSGS)CompletedNCT00193648Phase 1
30Allogenic AD-MSC Transplantation in Idiopathic Nephrotic Syndrome (Focal Segmental Glomerulosclerosis)RecruitingNCT02382874Phase 1
31A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte DiseasesRecruitingNCT02639260Phase 1
32Stem Cell Therapy for Patients With Focal Segmental GlomerulosclerosisActive, not recruitingNCT02693366Phase 1
33Safety and Pharmacokinetics of FG-3019 in Adolescents and Adults With Focal Segmental Glomerulosclerosis (FSGS)TerminatedNCT00782561Phase 1
34Effect of Oral Galactose on Focal Segmental Glomerulosclerosis (FSGS) Permeability FactorTerminatedNCT00816478Phase 1
35Effect of Galactose on Permeblity Factor in Patients With FSGS and CKD Stage 5WithdrawnNCT00816504Phase 1
36Therapeutic Effect of Low-dose Prednisone Combined With MMF and FK506 in Focal Segmental GlomerulosclerosisUnknown statusNCT00956059
37Prednisone Plus Tripterygium Wilfordii Treatment of Adult Patients With Idiopathic Focal Segmental GlomerulosclerosisCompletedNCT00801463
38Oral Galactose in Children With Steroid Resistant Nephrotic SyndromeCompletedNCT01113385
39Regional Citrate Anticoagulation in Plasma Exchange TreatmentCompletedNCT01370200
40Kidney Disease BiomarkersCompletedNCT00255398
41Evaluation of Albuminuria HIV-Infected PatientsCompletedNCT00524992
42The Effects of Helicobacter Pylori Eradication on Proteinuria in Patients With Membranous NephropathyCompletedNCT00983034
43Lupus Nephritis Biomarker Study: Baseline Characteristics of PatientsCompletedNCT01470183
44Role of Donor Genetics and Recipient Genetics in Kidney Transplant OutcomesCompletedNCT01143532
45Genetic Markers for Focal Segmental GlomerulosclerosisRecruitingNCT00001393
46Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in ChildrenRecruitingNCT02235857
47Proteinuria in Pre and Post TransplantRecruitingNCT01094327
48Nephrotic Syndrome Study NetworkRecruitingNCT01209000
49A Prospective Controlled Study of Serum suPAR in the CsA-treated FSGS PatientsRecruitingNCT01468493
50Pathogenesis of GlomerulosclerosisRecruitingNCT00001392

Search NIH Clinical Center for Focal Segmental Glomerulosclerosis

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: glomerulosclerosis, focal segmental

Genetic Tests for Focal Segmental Glomerulosclerosis

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Genetic tests related to Focal Segmental Glomerulosclerosis:

id Genetic test Affiliating Genes
1 Focal Segmental Glomerulosclerosis27 24 TRPC6

Anatomical Context for Focal Segmental Glomerulosclerosis

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MalaCards organs/tissues related to Focal Segmental Glomerulosclerosis:

36
Kidney, Heart, Endothelial, Testes, Myeloid, Neutrophil, Ovary

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Focal Segmental Glomerulosclerosis:
id TissueAnatomical CompartmentCell Relevance
1 KidneyPodocyte LayerPodocytes Potential therapeutic candidate, affected by disease

Publications for Focal Segmental Glomerulosclerosis

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Articles related to Focal Segmental Glomerulosclerosis:

(show top 50)    (show all 705)
idTitleAuthorsYear
1
Urinary Exosomal miR-193a Can Be a Potential Biomarker for the Diagnosis of Primary Focal Segmental Glomerulosclerosis in Children. (28246603)
2017
2
Focal segmental glomerulosclerosis and medullary nephrocalcinosis in children with ADCK4 mutations. (28405841)
2017
3
Focal Segmental Glomerulosclerosis in a Patient with Ambiguous Genitalia: A Diagnostic Dilemma. (28333603)
2017
4
Complex glomerular pathology of thrombotic microangiopathy and focal segmental glomerulosclerosis forms tumor-like mass in a renal transplant donor with severe renovascular hypertension. (28509120)
2017
5
A child with phenylketonuria and focal segmental glomerulosclerosis, the bright side of proteinuria. (28386663)
2017
6
Focal segmental glomerulosclerosis lagged behind the onset of rheumatoid arthritis by 7 years: A case report and literature review. (28072731)
2017
7
Evidence from the Oxford Classification cohort supports the clinical value of subclassification ofA focal segmental glomerulosclerosis in IgAA nephropathy. (27914703)
2017
8
Does copy number variation of APOL1 gene affect the susceptibility to focal segmental glomerulosclerosis? (28494221)
2017
9
What are we missing in the clinical trials of focal segmental glomerulosclerosis? (28391338)
2017
10
Development of proteinuria and focal segmental glomerulosclerosis during direct acting antiviral therapy for hepatitis C virus infection (HEP-16-2474.R1). (28211090)
2017
11
Role of Protease-Activated Receptor 2 in Regulating Focal Segmental Glomerulosclerosis. (28245472)
2017
12
Calcineurin Inhibitors in the Treatment of Primary Focal Segmental Glomerulosclerosis: A Systematic Review and Meta-analysis of the Literature. (28321320)
2017
13
Truncating Wilms Tumor Suppressor Gene 1 Mutation in an XX Female with Adult-Onset Focal Segmental Glomerulosclerosis and Streak Ovaries: A Case Report. (27701157)
2017
14
Remission of post-transplant focal segmental glomerulosclerosis with angiotensin receptor blockers. (28356673)
2017
15
Focal segmental glomerulosclerosis in atypical polycystic kidney disease. (28063418)
2017
16
Unwinding focal segmental glomerulosclerosis. (28491286)
2017
17
Focal Segmental Glomerulosclerosis. (28242845)
2017
18
Fatal proteinuric kidney disease in a 30-month-old German Fleckvieh heifer caused by unilateral focal segmental glomerulosclerosis subsequent to a non-functional counterpart kidney. (28248187)
2017
19
Comparative differential proteomic analysis of minimal change disease and focal segmental glomerulosclerosis. (28158993)
2017
20
Cyclosporine-based immunosuppressive therapy for patients with steroid-resistant focal segmental glomerulosclerosis: a meta-analysis. (28436233)
2017
21
Chylous ascites in focal segmental glomerulosclerosis. (28314586)
2017
22
Unsuccessful Treatment with Abatacept in Recurrent Focal Segmental Glomerulosclerosis after Kidney Transplantation. (28203563)
2017
23
Removal of focal segmental glomerulosclerosis (FSGS) factor suPAR using CytoSorb. (28370393)
2017
24
Clinical presentation, treatment and outcome of focal segmental glomerulosclerosis in Far North Queensland Australian adults. (27170059)
2016
25
Up-Regulation of CD74 Expression in Parietal Epithelial Cells in a Mouse Model of Focal Segmental Glomerulosclerosis. (27463800)
2016
26
A Clinicopathologic Study of Children with Idiopathic Focal Segmental Glomerulosclerosis. (27054662)
2016
27
Update on the treatment of focal segmental glomerulosclerosis in renal transplantation. (27011905)
2016
28
Circulating Permeability Factors in Primary Focal Segmental Glomerulosclerosis: A Review of Proposed Candidates. (27200372)
2016
29
Glomerular epithelial cells in secondary focal segmental glomerulosclerosis. (27181784)
2016
30
Post-Transplant Recurrence of Focal Segmental Glomerulosclerosis in a Child With Heterozygous Mutations in NPHS1 and NPHS2. (27312921)
2016
31
Aberrant Blood Vessel Formation Connecting the Glomerular Capillary Tuft and the Interstitium Is a Characteristic Feature of Focal Segmental Glomerulosclerosis-like IgA Nephropathy. (27068024)
2016
32
Idiopathic collapsing focal segmental glomerulosclerosis in an 81-year-old Japanese woman: a case report and review of the literature. (28508976)
2016
33
Light Chain Podocytopathy Mimicking Recurrent Focal Segmental Glomerulosclerosis. (27775221)
2016
34
The role of plasma exchange in treating post-transplant focal segmental glomerulosclerosis: A systematic review and meta-analysis of 77 case-reports and case-series. (27473582)
2016
35
Clinicopathological correlation and treatment response of primary focal segmental glomerulosclerosis in adults and adolescents. (27795629)
2016
36
A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis. (26927868)
2016
37
Successful Preemptive Kidney Transplantation With Rituximab Induction in a Patient With Focal Segmental Glomerulosclerosis and Massive Nephrotic Syndrome: A Case Report. (27932154)
2016
38
Posterior reversible encephalopathy syndrome in malignant hypertension secondary to focal segmental glomerulosclerosis. (27535734)
2016
39
Focal segmental glomerulosclerosis: it may no longer be all about podocytes. (27633870)
2016
40
Rituximab for Recurrence of Primary Focal Segmental Glomerulosclerosis After Kidney Transplantation: Clinical Outcomes. (27043407)
2016
41
Infection-Related Focal Segmental Glomerulosclerosis in Children. (27294131)
2016
42
A novel heterozygous COL4A4 missense mutation in a Chinese family with focal segmental glomerulosclerosis. (27469977)
2016
43
Treatment of Focal Segmental Glomerulosclerosis Recurrence in the Renal Allograft: A Report of Two Cases. (27099858)
2016
44
Functional Validation of an Alpha-Actinin-4 Mutation as a Potential Cause of an Aggressive Presentation of Adolescent Focal Segmental Glomerulosclerosis: Implications for Genetic Testing. (27977723)
2016
45
Treatment Strategies of Adult Primary Focal Segmental Glomerulosclerosis: A Systematic Review Focusing on the Last Two Decades. (27144166)
2016
46
Successful Treatment of Focal Segmental Glomerulosclerosis after Kidney Transplantation with Plasma Exchange and Abatacept in a Patient with Juvenile Rheumatoid Arthritis. (27088031)
2016
47
Interferon Induced Focal Segmental Glomerulosclerosis. (27847659)
2016
48
Secondary Focal Segmental Glomerulosclerosis: From Podocyte Injury to Glomerulosclerosis. (27088082)
2016
49
A CD2AP Mutation Associated with Focal Segmental Glomerulosclerosis in Young Adulthood. (26997877)
2016
50
Soluble Urokinase Receptors in Focal Segmental Glomerulosclerosis: A Review on the Scientific Point of View. (27504461)
2016

Variations for Focal Segmental Glomerulosclerosis

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Expression for genes affiliated with Focal Segmental Glomerulosclerosis

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Search GEO for disease gene expression data for Focal Segmental Glomerulosclerosis.

Pathways for genes affiliated with Focal Segmental Glomerulosclerosis

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Pathways related to Focal Segmental Glomerulosclerosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7ACTN4, CD2AP, NPHS1
29.5CD2AP, NPHS1, NPHS2, TRPC6
39.2ACTN4, COL4A3, LAMB2
45.6ACTN4, CD2AP, CDKN1C, COL4A3, INF2, LAMB2

GO Terms for genes affiliated with Focal Segmental Glomerulosclerosis

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Cellular components related to Focal Segmental Glomerulosclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cortical cytoskeletonGO:003086310.4ACTN4, MYH9
2cell-cell junctionGO:000591110.2ACTN4, CD2AP, MYO1E, NPHS2
3brush borderGO:000590310.2ACTN4, MYH9, MYO1E
4actomyosin contractile ringGO:00058269.8ANLN, MYH9
5slit diaphragmGO:00360579.8NPHS1, NPHS2, TRPC6
6actin cytoskeletonGO:00156298.8ACTN4, ANLN, CD2AP, MYH9, MYO1E, SYNPO
7protein complexGO:00432348.6ACTN4, CD2AP, CRB2, MYH9, NPHS2, PAX2
8extracellular exosomeGO:00700627.9ACTN4, CD2AP, CRB2, LAMB2, MYH9, MYO1E

Biological processes related to Focal Segmental Glomerulosclerosis according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1glomerular visceral epithelial cell developmentGO:007201510.6MYO1E, NPHS1
2adrenal gland developmentGO:003032510.4CDKN1C, WT1
3glomerular visceral epithelial cell differentiationGO:007211210.4PTPRO, WT1
4glomerulus developmentGO:003283510.4PTPRO, WT1
5mesenchymal to epithelial transitionGO:006023110.4PAX2, WT1
6metanephric epithelium developmentGO:007220710.4PAX2, WT1
7metanephric mesenchyme developmentGO:007207510.3PAX2, WT1
8actin filament-based movementGO:003004810.2MYH9, MYO1E
9metanephric glomerular visceral epithelial cell developmentGO:007224910.1LAMB2, NPHS2
10camera-type eye developmentGO:004301010.1CDKN1C, PAX2, WT1
11kidney developmentGO:000182210.0CDKN1C, MYO1E, WT1
12myoblast fusionGO:00075209.9MYH9, NPHS1
13glomerular basement membrane developmentGO:00328369.7COL4A3, MYO1E, NPHS1, WT1
14regulation of exit from mitosisGO:00070969.3ANLN, CDKN1C

Molecular functions related to Focal Segmental Glomerulosclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1actin filament bindingGO:005101510.0ACTN4, MYH9, MYO1E
2microfilament motor activityGO:00001469.6MYH9, MYO1E
3integrin bindingGO:00051789.6ACTN4, COL4A3, LAMB2
4actin bindingGO:00037798.5ACTN4, ANLN, INF2, MYH9, MYO1E, SYNPO

Sources for Focal Segmental Glomerulosclerosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet