MCID: FLL013
MIFTS: 41

Follicular Dendritic Cell Sarcoma malady

Categories: Cancer diseases, Blood diseases, Rare diseases, Immune diseases

Aliases & Classifications for Follicular Dendritic Cell Sarcoma

About this section
Sources:
11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 38MeSH, 39MESH via Orphanet, 44NCIt, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Follicular Dendritic Cell Sarcoma:

Name: Follicular Dendritic Cell Sarcoma 11 53 13
Dendritic Cell Sarcoma, Not Otherwise Specified 11 67
Dendritic Cell Sarcoma, Follicular 38 67
Dendritic Cell Sarcoma 11 13
 
Dendritic Cell Sarcoma Not Otherwise Specified 53
Dendritic Cell Sarcoma, Interdigitating 67
Follicular Dendritic Cell Tumour 11

Characteristics:

Orphanet epidemiological data:

53
follicular dendritic cell sarcoma:
Age of onset: All ages

Classifications:



External Ids:

Disease Ontology11 DOID:6262, DOID:7849
ICD1029 C96.4
MeSH38 D054740
UMLS via Orphanet68 C1301364, C1260325
ICD10 via Orphanet30 C96.4
MESH via Orphanet39 D054740

Summaries for Follicular Dendritic Cell Sarcoma

About this section
Wikipedia:70 Follicular dendritic cell sarcoma (FDCS) is an extremely rare neoplasm. While the existence of FDC... more...

MalaCards based summary: Follicular Dendritic Cell Sarcoma, also known as dendritic cell sarcoma, not otherwise specified, is related to dendritic cell tumor and sarcoma, and has symptoms including fatigue, hepatomegaly and night sweats. An important gene associated with Follicular Dendritic Cell Sarcoma is CR2 (Complement C3d Receptor 2), and among its related pathways are IgA-Producing B Cells in the Intestine and Immune response Lectin induced complement pathway. Affiliated tissues include tonsil, lymph node and liver, and related mouse phenotype immune system.

Disease Ontology:11 A dendritic cell sarcoma cancer that effects the follicular dendritic cells.

Related Diseases for Follicular Dendritic Cell Sarcoma

About this section

Diseases related to Follicular Dendritic Cell Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 64)
idRelated DiseaseScoreTop Affiliating Genes
1dendritic cell tumor11.4
2sarcoma10.9
3penile urethral cancer10.5CR1, CR2
4pancreatic intraductal papillary-mucinous adenoma10.4CR1, CR2
5prostate stromal sarcoma10.4CR1, CR2
6angioma hereditary neurocutaneous10.4CR1, CR2
7tonsillitis10.4
8pemphigus10.4
9cerebral arterial disease10.4CR1, CR2
10paraneoplastic pemphigus10.4
11mediastinitis10.2
12vulvar liposarcoma10.2CR2, KIT
13myasthenia gravis10.1
14short-rib thoracic dysplasia 1210.1CR1, CR2, FCER2
15tropical spastic paraparesis10.1DSP, KIT
16acute poisoning by drugs with membrane-stabilizing effect10.1DSG1, DSP
17cardiomyopathy, dilated, 1bb10.1DSG1, DSP
18epicardium cancer10.1DSP, KIT
19pharyngitis10.0
20thyroiditis10.0
21castleman disease10.0
22mixed extragonadal germ cell cancer10.0CR1, CR2, KIT
23malignant type ab thymoma10.0CD68, CR2
24peripheral t-cell lymphoma10.0DSG1, DSP
25hepatitis9.9
26cervicitis9.9
27autism spectrum disorder9.9DSG1, DSP
28impetigo9.9DSG1, DSP
29lipoma9.9DSG1, DSP
30paratesticular lipoma9.9CD68, KIT
31adhesions of uterus9.9CD68, KIT
32multiple chemical sensitivity9.8CD68, KIT
33cirrhotic cardiomyopathy9.8DSG1, DSP
34clivus chordoma9.8CD68, PPP3CA
35ureter squamous cell carcinoma9.8CD68, KIT
36breast cancer9.8
37kaposi sarcoma9.8
38nasopharyngeal carcinoma9.8
39reticulum cell sarcoma9.8
40arthritis9.8
41leukemia9.8
42lymphoma9.8
43nasopharyngitis9.8
44thymoma9.8
45liposarcoma9.8
46cellulitis9.8
47interdigitating dendritic cell sarcoma9.8
48peritonitis9.8
49appendicitis9.8
50myeloid leukemia9.8

Graphical network of the top 20 diseases related to Follicular Dendritic Cell Sarcoma:



Diseases related to follicular dendritic cell sarcoma

Symptoms for Follicular Dendritic Cell Sarcoma

About this section

UMLS symptoms related to Follicular Dendritic Cell Sarcoma:


fatigue, hepatomegaly, night sweats

Drugs & Therapeutics for Follicular Dendritic Cell Sarcoma

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Follicular Dendritic Cell Sarcoma


Cochrane evidence based reviews: dendritic cell sarcoma, follicular

Genetic Tests for Follicular Dendritic Cell Sarcoma

About this section

Anatomical Context for Follicular Dendritic Cell Sarcoma

About this section

MalaCards organs/tissues related to Follicular Dendritic Cell Sarcoma:

35
Tonsil, Lymph node, Liver, Spleen, Colon, T cells, Brain

Animal Models for Follicular Dendritic Cell Sarcoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Follicular Dendritic Cell Sarcoma:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.1CD68, CLU, CR2, FCER2, KIT, PPP3CA

Publications for Follicular Dendritic Cell Sarcoma

About this section

Articles related to Follicular Dendritic Cell Sarcoma:

(show top 50)    (show all 195)
idTitleAuthorsYear
1
Follicular Dendritic Cell Sarcoma of Appendix Presenting as Acute Appendicitis: An Exceptionally Rare Case Report. (27225654)
2016
2
Computer Tomography Imaging Findings of Abdominal Follicular Dendritic Cell Sarcoma: A Report of 5 Cases. (26735543)
2016
3
Follicular dendritic cell tumour/sarcoma: a commonly misdiagnosed tumour in the thorax Intrathoracic follicular dendritic cell sarcoma. (27206572)
2016
4
Response to rituximab in an anti-muscle-specific receptor tyrosine kinase- and anti-acetylcholine recepto-double-positive myasthenia gravis patient concomitant with follicular dendritic cell sarcoma. (26818174)
2016
5
Paraneoplastic arthritis as first symptom of a liver inflammatory pseudotumor-like follicular dendritic cell sarcoma. (27125361)
2016
6
Synchronous presentation of intra-nodal follicular dendritic cell sarcoma and Castleman disease. (27862216)
2016
7
Paraneoplastic pemphigus and myasthenia gravis, associated with inflammatory pseudotumor-like follicular dendritic cell sarcoma: response to rituximab. (27525088)
2016
8
Follicular Dendritic Cell Sarcoma: Cytogenetics and pathological findings. (26355964)
2015
9
Follicular dendritic cell sarcoma of the tonsil. (25512260)
2015
10
Targeted genomic sequencing of follicular dendritic cell sarcoma reveals recurrent alterations in NF-I_B regulatory genes. (26564005)
2015
11
Follicular dendritic cell sarcoma: two rare cases and a brief review of the literature. (26244020)
2015
12
Extranodal follicular dendritic cell sarcoma: A clinicopathological report of four cases and a literature review. (25435998)
2015
13
Extranodal follicular dendritic cell sarcoma of the soft palate: a case report. (25674273)
2014
14
Follicular Dendritic Cell Sarcoma Presenting As a Thyroid Mass. (24663046)
2014
15
Recalcitrant paraneoplastic pemphigus associated with follicular dendritic cell sarcoma: response to prolonged rituximab and ciclosporin therapy. (25367731)
2014
16
Mediastinal follicular dendritic cell sarcoma with paraneoplastic pemphigus. (25406405)
2014
17
Follicular dendritic cell sarcoma of the stomach: case report and review of the literature. (25489266)
2014
18
Inflammatory pseudotumor-like follicular dendritic cell sarcoma of the spleen: a report of six cases with increased IgG4-positive plasma cells. (23714251)
2013
19
A rare case of follicular dendritic cell sarcoma involving multiple bones. (23640234)
2013
20
Transformation of Castleman's disease into follicular dendritic cell sarcoma, presenting as an asymptomatic intra-abdominal mass. (23981949)
2013
21
Cytogenetic abnormalities in follicular dendritic cell sarcoma: report of two cases and literature review. (23422480)
2013
22
Follicular dendritic cell sarcoma of the tonsil. (23415609)
2013
23
Intraabdominal follicular dendritic cell sarcoma: a report of three cases and review of the literature. (23748832)
2013
24
Extranodal follicular dendritic cell sarcoma with rapid growth in parapharynx: a case report. (23110021)
2012
25
Follicular dendritic cell sarcoma of the tonsil. (23251062)
2012
26
Follicular dendritic cell sarcoma: a diagnostic challenge ! (22842383)
2012
27
Follicular dendritic cell sarcoma of the liver: unusual presentation of a rare tumor and literature review. (21813397)
2011
28
Follicular dendritic cell sarcoma of the lung: a report of two cases highlighting its pathological features and diagnostic pitfalls. (21240069)
2011
29
Cervical follicular dendritic cell sarcoma: a case report and review of the literature. (21658332)
2011
30
Imaging findings of follicular dendritic cell sarcoma: report of four cases. (21228948)
2011
31
Hepatic follicular dendritic cell sarcoma favorably controlled by transcatheter arterial chemoembolization. (21173546)
2010
32
Extranodal follicular dendritic cell sarcoma of the pharyngeal region: a potential diagnostic pitfall, with literature review. (20023258)
2010
33
Follicular dendritic cell sarcoma of small intestine with aberrant T-cell marker expression. (19883432)
2009
34
Follicular dendritic cell sarcoma with microtubuloreticular structure and virus-like particle production in vitro. (19432677)
2009
35
Follicular dendritic cell sarcoma of the parotid gland recurring 6 times within 12 years. (19884836)
2009
36
SIR 2008 annual meeting film panel case: Castleman disease complicated by follicular dendritic cell sarcoma. (18656005)
2008
37
Cytogenetic abnormality 46,XX,add(21)(q11.2) in a patient with follicular dendritic cell sarcoma. (18786443)
2008
38
Interwoven dendritic processes of follicular dendritic cell sarcoma demonstrated on ultrafast papanicolaou-stained smears: a case report. (17017440)
2006
39
Nodal follicular dendritic cell sarcoma of the axilla presenting as cellulitis. (16403115)
2006
40
Retroperitoneal follicular dendritic cell sarcoma. (16867894)
2006
41
Autoantibody production from a thymoma and a follicular dendritic cell sarcoma associated with paraneoplastic pemphigus. (16120143)
2005
42
Follicular dendritic cell sarcoma: case report and review of current management principles. (16343408)
2005
43
Intracranial follicular dendritic cell sarcoma. Case report. (14705740)
2003
44
Mediastinal follicular dendritic cell sarcoma. (12604428)
2003
45
Epidermal growth factor receptor expression in follicular dendritic cells: a shared feature of follicular dendritic cell sarcoma and Castleman's disease. (14562277)
2003
46
Follicular dendritic cell sarcoma of the neck; a case report and literature review. (12393051)
2002
47
Follicular dendritic cell sarcoma of the colon mimicking stromal tumour. (11135043)
2001
48
Extranodal follicular dendritic cell sarcoma of the palate. (10052377)
1999
49
Follicular dendritic cell sarcoma and interdigitating reticulum cell sarcoma: a review. (9766802)
1998
50
Follicular dendritic cell sarcoma. Clinicopathologic analysis of 17 cases suggesting a malignant potential higher than currently recognized. (9010103)
1997

Variations for Follicular Dendritic Cell Sarcoma

About this section

Expression for genes affiliated with Follicular Dendritic Cell Sarcoma

About this section
Search GEO for disease gene expression data for Follicular Dendritic Cell Sarcoma.

Pathways for genes affiliated with Follicular Dendritic Cell Sarcoma

About this section

GO Terms for genes affiliated with Follicular Dendritic Cell Sarcoma

About this section

Cellular components related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmic side of plasma membraneGO:00098989.8DSG1, KIT
2extracellular matrixGO:00310129.5CLU, DSG1, DSP
3cell-cell junctionGO:00059119.4DSG1, DSP, KIT
4desmosomeGO:00300579.3DSG1, DSP
5extracellular exosomeGO:00700628.0CLU, CR1, CR2, DSG1, DSP, FCER2
6plasma membraneGO:00058867.3CD68, CR1, CR2, DSG1, DSP, FCER2

Biological processes related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1complement receptor mediated signaling pathwayGO:00024309.8CR1, CR2
2complement activation, classical pathwayGO:00069589.1CLU, CR1, CR2

Molecular functions related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1virus receptor activityGO:00016189.8CR1, CR2

Sources for Follicular Dendritic Cell Sarcoma

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet