MCID: FLL013
MIFTS: 39

Follicular Dendritic Cell Sarcoma

Categories: Cancer diseases, Blood diseases, Rare diseases, Immune diseases

Aliases & Classifications for Follicular Dendritic Cell Sarcoma

MalaCards integrated aliases for Follicular Dendritic Cell Sarcoma:

Name: Follicular Dendritic Cell Sarcoma 12 12 56 14
Dendritic Cell Sarcoma, Not Otherwise Specified 12 69
Dendritic Cell Sarcoma, Follicular 42 69
Dendritic Cell Sarcoma 12 14
Dendritic Cell Sarcoma Not Otherwise Specified 56
Dendritic Cell Sarcoma, Interdigitating 69
Follicular Dendritic Cell Tumour 12

Characteristics:

Orphanet epidemiological data:

56
follicular dendritic cell sarcoma
Age of onset: All ages;

Classifications:



External Ids:

Disease Ontology 12 DOID:6262 DOID:7849
ICD10 33 C96.4
MeSH 42 D054740
NCIt 47 C9281 C27260
UMLS via Orphanet 70 C1301364 C1260325
ICD10 via Orphanet 34 C96.4
MESH via Orphanet 43 D054740

Summaries for Follicular Dendritic Cell Sarcoma

Disease Ontology : 12 A dendritic cell sarcoma cancer that effects the follicular dendritic cells.

MalaCards based summary : Follicular Dendritic Cell Sarcoma, also known as dendritic cell sarcoma, not otherwise specified, is related to sarcoma and central breast papilloma, and has symptoms including fatigue, fever and night sweats. An important gene associated with Follicular Dendritic Cell Sarcoma is CR2 (Complement C3d Receptor 2), and among its related pathways/superpathways are Innate Immune System and Epstein-Barr virus infection. Affiliated tissues include tonsil, lymph node and liver.

Wikipedia : 72 Follicular dendritic cell sarcoma (FDCS) is an extremely rare neoplasm. While the existence of FDC... more...

Related Diseases for Follicular Dendritic Cell Sarcoma

Diseases related to Follicular Dendritic Cell Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
id Related Disease Score Top Affiliating Genes
1 sarcoma 11.0
2 central breast papilloma 10.6 CR1 CR2
3 adult central nervous system germinoma 10.6 CR1 CR2
4 rectum leiomyoma 10.6 CR1 CR2
5 tang hsi ryu syndrome 10.6 CR1 CR2
6 cataract congenital autosomal dominant 10.6 CR1 CR2
7 anterior cerebral artery infarction 10.5 CR1 CR2
8 familial idiopathic steroid-resistant nephrotic syndrome with minimal changes 10.5 CR1 CR2
9 tonsillitis 10.4
10 pemphigus 10.4
11 ascaridiasis 10.4 CR2 MDM2
12 paraneoplastic pemphigus 10.3
13 large cell acanthoma 10.3 CR2 KIT
14 small cell osteogenic sarcoma 10.3 CLU MDM2
15 conventional central osteosarcoma 10.2 CLU MDM2
16 mediastinitis 10.2
17 brain stem infarction 10.2 KIT MDM2
18 short-rib thoracic dysplasia 12 10.2 CR1 CR2 FCER2
19 dense deposit disease 10.2 CR1 CR2 FCER2
20 lung leiomyosarcoma 10.2 KIT MDM2
21 peri-anal fistula 10.1 DSP PPL
22 myasthenia gravis 10.1
23 autism spectrum disorder 10.1 DSP PPL
24 enamel hypoplasia cataract hydrocephaly 10.1 KIT MDM2
25 demyelinating disease 10.1 DSP KIT
26 vagina, absence of 10.1 KIT MDM2
27 prostate disease 10.0 DSP KIT
28 extraosseous osteosarcoma 10.0 KIT MDM2
29 pharyngitis 10.0
30 thyroiditis 10.0
31 castleman disease 10.0
32 dermatitis herpetiformis 10.0 DSP PPL
33 lung clear cell-sugar-tumor 10.0 KIT MDM2
34 c-p angle neurinoma 10.0 DSP MDM2
35 mediastinum rhabdomyosarcoma 10.0 KIT MDM2
36 smoking as a quantitative trait locus 1 10.0 CR2 FCER2 MDM2
37 hepatitis 9.9
38 lymphoma 9.9
39 cervicitis 9.9
40 classic hairy cell leukemia 9.9 DSP PPL
41 cutaneous liposarcoma 9.9 CR2 KIT MDM2
42 gestational choriocarcinoma 9.9 KIT MDM2
43 breast cancer 9.8
44 kaposi sarcoma 9.8
45 nasopharyngeal carcinoma 9.8
46 reticulum cell sarcoma 9.8
47 arthritis 9.8
48 leukemia 9.8
49 nasopharyngitis 9.8
50 squamous cell carcinoma 9.8

Graphical network of the top 20 diseases related to Follicular Dendritic Cell Sarcoma:



Diseases related to Follicular Dendritic Cell Sarcoma

Symptoms & Phenotypes for Follicular Dendritic Cell Sarcoma

UMLS symptoms related to Follicular Dendritic Cell Sarcoma:


fatigue, fever, night sweats

Drugs & Therapeutics for Follicular Dendritic Cell Sarcoma

Search Clinical Trials , NIH Clinical Center for Follicular Dendritic Cell Sarcoma

Cochrane evidence based reviews: dendritic cell sarcoma, follicular

Genetic Tests for Follicular Dendritic Cell Sarcoma

Anatomical Context for Follicular Dendritic Cell Sarcoma

MalaCards organs/tissues related to Follicular Dendritic Cell Sarcoma:

39
Tonsil, Lymph Node, Liver, Spleen, T Cells, Breast, Thyroid

Publications for Follicular Dendritic Cell Sarcoma

Articles related to Follicular Dendritic Cell Sarcoma:

(show top 50) (show all 208)
id Title Authors Year
1
Follicular Dendritic Cell Sarcoma. ( 28353378 )
2017
2
Identification of novel follicular dendritic cell sarcoma markers, FDCSP and SRGN, by whole transcriptome sequencing. ( 28145886 )
2017
3
"Medusa-Head" cells, "Starfish" cells, and interconnecting long cytoplasmic processes as diagnostic cytologic clues for follicular dendritic cell sarcoma in fine needle aspiration samples. ( 28160447 )
2017
4
Follicular dendritic cell sarcoma of the small intestine detected by double-balloon enteroscopy. ( 28543909 )
2017
5
Genomic analysis of follicular dendritic cell sarcoma by molecular inversion probe array reveals tumor suppressor-driven biology. ( 28621320 )
2017
6
Primary follicular dendritic cell sarcoma of the urinary bladder: the first case report and potential diagnostic pitfalls. ( 28438212 )
2017
7
Mediastinitis After Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration of a Follicular Dendritic Cell Sarcoma. ( 28843365 )
2017
8
Follicular dendritic cell sarcoma of the head and neck. Literature review and report of the tonsil occurrence in a Ugandan patient. ( 28748971 )
2017
9
Follicular dendritic cell sarcoma of the liver with metachronous small bowel and splenic metastases: a case report and literature review. ( 28653001 )
2017
10
Angioimmunoblastic T-Cell Lymphoma: A Questionable Association with Follicular Dendritic Cell Sarcoma. ( 28197348 )
2017
11
p16 expression in follicular dendritic cell sarcoma: a potential mimicker of human papillomavirus-related oropharyngeal squamous cell carcinoma. ( 28554574 )
2017
12
Characteristics, management, and outcomes of patients with follicular dendritic cell sarcoma. ( 28382648 )
2017
13
Small intestine follicular dendritic cell sarcoma with liver metastasis: A case report. ( 28767565 )
2017
14
Follicular Dendritic Cell Sarcoma. ( 26910224 )
2016
15
MDM2 Expression in Extranodal Abdominal and Retroperitoneal Follicular Dendritic Cell Sarcomas, Mimicking Dedifferentiated Liposarcomas. ( 26180935 )
2016
16
Treatment of breast cancer 2 (BRCA2)-mutant follicular dendritic cell sarcoma with a poly ADP-ribose polymerase (PARP) inhibitor: a case report. ( 27488020 )
2016
17
A Rare Case of Epstein-Barr Virus Negative Inflammatory Pseudotumor-like Follicular Dendritic Cell Sarcoma Presenting as a Solitary Colonic Mass in a 53-Year-Old Woman; Case Report and Review of Literature. ( 27299190 )
2016
18
Follicular Dendritic Cell Sarcoma of Appendix Presenting as Acute Appendicitis: An Exceptionally Rare Case Report. ( 27225654 )
2016
19
Paraneoplastic arthritis as first symptom of a liver inflammatory pseudotumor-like follicular dendritic cell sarcoma. ( 27125361 )
2016
20
(18)F-FDG PET/CT follow-up of follicular dendritic cell sarcoma. ( 27793634 )
2016
21
Completely resected follicular dendritic cell sarcoma of the posterior mediastinum: report of a case. ( 27001632 )
2016
22
Clinicopathological characteristics of mediastinal follicular dendritic cell sarcoma: report of three cases. ( 27068522 )
2016
23
High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model. ( 27105519 )
2016
24
Response to rituximab in an anti-muscle-specific receptor tyrosine kinase- and anti-acetylcholine recepto-double-positive myasthenia gravis patient concomitant with follicular dendritic cell sarcoma. ( 26818174 )
2016
25
Cytological features of inflammatory pseudotumor-like follicular dendritic cell sarcoma of spleen: A case report. ( 27775241 )
2016
26
Computer Tomography Imaging Findings of Abdominal Follicular Dendritic Cell Sarcoma: A Report of 5 Cases. ( 26735543 )
2016
27
Poster 10 Successful Rehabilitation Outcome from Rare Brain Tumor (Intracranial Follicular Dendritic Cell Sarcoma): A Case Report. ( 27672780 )
2016
28
Clinicopathological Profile and Outcomes of Follicular Dendritic Cell Sarcoma of the Head and Neck Region - A Study of 10 Cases with Literature Review. ( 27656545 )
2016
29
Follicular dendritic cell tumour/sarcoma: a commonly misdiagnosed tumour in the thorax Intrathoracic follicular dendritic cell sarcoma. ( 27206572 )
2016
30
Paraneoplastic pemphigus and myasthenia gravis, associated with inflammatory pseudotumor-like follicular dendritic cell sarcoma: response to rituximab. ( 27525088 )
2016
31
Follicular dendritic cell sarcoma of the spleen: A case report and review of the literature. ( 27602139 )
2016
32
Follicular dendritic cell sarcoma: clinicopathologic study of 15 cases with emphasis on novel expression of MDM2, somatostatin receptor 2A, and PD-L1. ( 27402219 )
2016
33
Synchronous presentation of intra-nodal follicular dendritic cell sarcoma and Castleman disease. ( 27862216 )
2016
34
Extranodal Follicular Dendritic Cell Sarcoma Originating in the Pancreas: A Case Report. ( 27082603 )
2016
35
Follicular dendritic cell sarcoma treated with a variety of chemotherapy. ( 27734516 )
2016
36
Follicular dendritic cell sarcoma of mediastinum: a key role of radiotherapy in a multidisciplinary approach. ( 26638926 )
2015
37
Follicular dendritic cell sarcoma with atypical features surrounding undescended testis: description of a rare case. ( 25889780 )
2015
38
Follicular dendritic cell sarcoma with extensive lymph node involvement: A case report. ( 26171038 )
2015
39
Extranodal follicular dendritic cell sarcoma: A clinicopathological report of four cases and a literature review. ( 25435998 )
2015
40
Intraperitoneal follicular dendritic cell sarcoma: role of chemotherapy and bone marrow allotransplantation in locally advanced disease? ( 25698886 )
2015
41
Follicular dendritic cell sarcoma of the tonsil. ( 25512260 )
2015
42
Clinical and pathological features of head and neck follicular dendritic cell sarcoma. ( 25831474 )
2015
43
Resection is an effective treatment for recurrent follicular dendritic cell sarcoma from retroperitoneum: unusual presentation of a rare tumor. ( 26221397 )
2015
44
A rare case of follicular dendritic cell sarcoma with pseudochylous effusion and review of literature from India. ( 25825580 )
2015
45
Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review. ( 25621026 )
2015
46
Follicular dendritic cell sarcoma: two rare cases and a brief review of the literature. ( 26244020 )
2015
47
High-risk follicular dendritic cell sarcoma of the tonsil mimicking nasopharyngeal carcinoma. ( 27003778 )
2015
48
Follicular dendritic cell sarcoma of the head and neck: Case report, literature review, and pooled analysis of 97 cases. ( 25917851 )
2015
49
Targeted genomic sequencing of follicular dendritic cell sarcoma reveals recurrent alterations in NF-I_B regulatory genes. ( 26564005 )
2015
50
Extranodal follicular dendritic cell sarcoma involving tonsil. ( 26712678 )
2015

Variations for Follicular Dendritic Cell Sarcoma

Expression for Follicular Dendritic Cell Sarcoma

Search GEO for disease gene expression data for Follicular Dendritic Cell Sarcoma.

Pathways for Follicular Dendritic Cell Sarcoma

GO Terms for Follicular Dendritic Cell Sarcoma

Cellular components related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.56 CD274 CLU CR1 KIT
2 plasma membrane GO:0005886 9.56 CD274 CR1 CR2 DSP FCER2 KIT
3 external side of plasma membrane GO:0009897 9.5 CD274 FCER2 KIT
4 cornified envelope GO:0001533 9.4 DSP PPL
5 ficolin-1-rich granule membrane GO:0101003 9.37 CR1 DSP
6 extracellular exosome GO:0070062 9.17 CD274 CLU CR1 CR2 DSP FCER2
7 desmosome GO:0030057 9.16 DSP PPL

Biological processes related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 complement activation, classical pathway GO:0006958 9.33 CLU CR1 CR2
2 regulation of complement activation GO:0030449 9.13 CLU CR1 CR2
3 complement receptor mediated signaling pathway GO:0002430 8.62 CR1 CR2

Molecular functions related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 8.62 DSP MDM2

Sources for Follicular Dendritic Cell Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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