MCID: FLL013
MIFTS: 41

Follicular Dendritic Cell Sarcoma malady

Categories: Cancer diseases, Blood diseases, Rare diseases, Immune diseases

Aliases & Classifications for Follicular Dendritic Cell Sarcoma

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Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 39MeSH, 40MESH via Orphanet, 45NCIt, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Follicular Dendritic Cell Sarcoma:

Name: Follicular Dendritic Cell Sarcoma 11 54 13
Dendritic Cell Sarcoma, Not Otherwise Specified 11 68
Dendritic Cell Sarcoma, Follicular 39 68
Dendritic Cell Sarcoma 11 13
 
Dendritic Cell Sarcoma Not Otherwise Specified 54
Dendritic Cell Sarcoma, Interdigitating 68
Follicular Dendritic Cell Tumour 11

Characteristics:

Orphanet epidemiological data:

54
follicular dendritic cell sarcoma:
Age of onset: All ages

Classifications:



External Ids:

Disease Ontology11 DOID:6262, DOID:7849
ICD1030 C96.4
MeSH39 D054740
UMLS via Orphanet69 C1301364, C1260325
ICD10 via Orphanet31 C96.4
MESH via Orphanet40 D054740

Summaries for Follicular Dendritic Cell Sarcoma

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Wikipedia:71 Follicular dendritic cell sarcoma (FDCS) is an extremely rare neoplasm. While the existence of FDC... more...

MalaCards based summary: Follicular Dendritic Cell Sarcoma, also known as dendritic cell sarcoma, not otherwise specified, is related to dendritic cell tumor and sarcoma, and has symptoms including fatigue, hepatomegaly and night sweats. An important gene associated with Follicular Dendritic Cell Sarcoma is CR2 (Complement C3d Receptor 2), and among its related pathways are IgA-Producing B Cells in the Intestine and Immune response Lectin induced complement pathway. Affiliated tissues include tonsil, lymph node and liver, and related mouse phenotypes are Synthetic lethal with vaccinia virus (VACV) infection and immune system.

Disease Ontology:11 A dendritic cell sarcoma cancer that effects the follicular dendritic cells.

Related Diseases for Follicular Dendritic Cell Sarcoma

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Diseases related to Follicular Dendritic Cell Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 64)
idRelated DiseaseScoreTop Affiliating Genes
1dendritic cell tumor11.4
2sarcoma10.9
3penile urethral cancer10.5CR1, CR2
4pancreatic intraductal papillary-mucinous adenoma10.4CR1, CR2
5prostate stromal sarcoma10.4CR1, CR2
6angioma hereditary neurocutaneous10.4CR1, CR2
7tonsillitis10.4
8pemphigus10.4
9cerebral arterial disease10.4CR1, CR2
10paraneoplastic pemphigus10.4
11mediastinitis10.2
12vulvar liposarcoma10.2CR2, KIT
13myasthenia gravis10.1
14short-rib thoracic dysplasia 1210.1CR1, CR2, FCER2
15tropical spastic paraparesis10.1DSP, KIT
16acute poisoning by drugs with membrane-stabilizing effect10.1DSG1, DSP
17cardiomyopathy, dilated, 1bb10.1DSG1, DSP
18epicardium cancer10.1DSP, KIT
19pharyngitis10.0
20thyroiditis10.0
21castleman disease10.0
22mixed extragonadal germ cell cancer10.0CR1, CR2, KIT
23malignant type ab thymoma10.0CD68, CR2
24peripheral t-cell lymphoma10.0DSG1, DSP
25hepatitis9.9
26cervicitis9.9
27autism spectrum disorder9.9DSG1, DSP
28impetigo9.9DSG1, DSP
29lipoma9.9DSG1, DSP
30paratesticular lipoma9.9CD68, KIT
31adhesions of uterus9.9CD68, KIT
32multiple chemical sensitivity9.8CD68, KIT
33cirrhotic cardiomyopathy9.8DSG1, DSP
34clivus chordoma9.8CD68, PPP3CA
35ureter squamous cell carcinoma9.8CD68, KIT
36breast cancer9.8
37kaposi sarcoma9.8
38nasopharyngeal carcinoma9.8
39reticulum cell sarcoma9.8
40arthritis9.8
41leukemia9.8
42lymphoma9.8
43nasopharyngitis9.8
44thymoma9.8
45liposarcoma9.8
46cellulitis9.8
47interdigitating dendritic cell sarcoma9.8
48peritonitis9.8
49appendicitis9.8
50myeloid leukemia9.8

Graphical network of the top 20 diseases related to Follicular Dendritic Cell Sarcoma:



Diseases related to follicular dendritic cell sarcoma

Symptoms & Phenotypes for Follicular Dendritic Cell Sarcoma

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UMLS symptoms related to Follicular Dendritic Cell Sarcoma:


fatigue, hepatomegaly, night sweats

GenomeRNAi Phenotypes related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00362-A8.1CD68, CLU, DSG1, PPP3CA

MGI Mouse Phenotypes related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.1CD68, CLU, CR2, FCER2, KIT, PPP3CA

Drugs & Therapeutics for Follicular Dendritic Cell Sarcoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Follicular Dendritic Cell Sarcoma


Cochrane evidence based reviews: dendritic cell sarcoma, follicular

Genetic Tests for Follicular Dendritic Cell Sarcoma

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Anatomical Context for Follicular Dendritic Cell Sarcoma

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MalaCards organs/tissues related to Follicular Dendritic Cell Sarcoma:

36
Tonsil, Lymph node, Liver, Spleen, Colon, T cells, Brain

Publications for Follicular Dendritic Cell Sarcoma

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Articles related to Follicular Dendritic Cell Sarcoma:

(show top 50)    (show all 195)
idTitleAuthorsYear
1
Follicular Dendritic Cell Sarcoma of Appendix Presenting as Acute Appendicitis: An Exceptionally Rare Case Report. (27225654)
2016
2
Computer Tomography Imaging Findings of Abdominal Follicular Dendritic Cell Sarcoma: A Report of 5 Cases. (26735543)
2016
3
Follicular dendritic cell tumour/sarcoma: a commonly misdiagnosed tumour in the thorax Intrathoracic follicular dendritic cell sarcoma. (27206572)
2016
4
Response to rituximab in an anti-muscle-specific receptor tyrosine kinase- and anti-acetylcholine recepto-double-positive myasthenia gravis patient concomitant with follicular dendritic cell sarcoma. (26818174)
2016
5
Paraneoplastic arthritis as first symptom of a liver inflammatory pseudotumor-like follicular dendritic cell sarcoma. (27125361)
2016
6
Synchronous presentation of intra-nodal follicular dendritic cell sarcoma and Castleman disease. (27862216)
2016
7
Paraneoplastic pemphigus and myasthenia gravis, associated with inflammatory pseudotumor-like follicular dendritic cell sarcoma: response to rituximab. (27525088)
2016
8
Poster 10 Successful Rehabilitation Outcome from Rare Brain Tumor (Intracranial Follicular Dendritic Cell Sarcoma): A Case Report. (27672780)
2016
9
A Rare Case of Epstein-Barr Virus Negative Inflammatory Pseudotumor-like Follicular Dendritic Cell Sarcoma Presenting as a Solitary Colonic Mass in a 53-Year-Old Woman; Case Report and Review of Literature. (27299190)
2016
10
Extranodal Follicular Dendritic Cell Sarcoma Originating in the Pancreas: A Case Report. (27082603)
2016
11
Completely resected follicular dendritic cell sarcoma of the posterior mediastinum: report of a case. (27001632)
2016
12
Follicular dendritic cell sarcoma: clinicopathologic study of 15 cases with emphasis on novel expression of MDM2, somatostatin receptor 2A, and PD-L1. (27402219)
2016
13
Clinicopathological Profile and Outcomes of Follicular Dendritic Cell Sarcoma of the Head and Neck Region - A Study of 10 Cases with Literature Review. (27656545)
2016
14
MDM2 Expression in Extranodal Abdominal and Retroperitoneal Follicular Dendritic Cell Sarcomas, Mimicking Dedifferentiated Liposarcomas. (26180935)
2016
15
Follicular dendritic cell sarcoma treated with a variety of chemotherapy. (27734516)
2016
16
Follicular Dendritic Cell Sarcoma. (26910224)
2016
17
(18)F-FDG PET/CT follow-up of follicular dendritic cell sarcoma. (27793634)
2016
18
Cytological features of inflammatory pseudotumor-like follicular dendritic cell sarcoma of spleen: A case report. (27775241)
2016
19
Clinicopathological characteristics of mediastinal follicular dendritic cell sarcoma: report of three cases. (27068522)
2016
20
Follicular dendritic cell sarcoma of the spleen: A case report and review of the literature. (27602139)
2016
21
High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model. (27105519)
2016
22
Treatment of breast cancer 2 (BRCA2)-mutant follicular dendritic cell sarcoma with a poly ADP-ribose polymerase (PARP) inhibitor: a case report. (27488020)
2016
23
Follicular Dendritic Cell Sarcoma: Cytogenetics and pathological findings. (26355964)
2015
24
Follicular dendritic cell sarcoma of the tonsil. (25512260)
2015
25
Targeted genomic sequencing of follicular dendritic cell sarcoma reveals recurrent alterations in NF-I_B regulatory genes. (26564005)
2015
26
Follicular dendritic cell sarcoma: two rare cases and a brief review of the literature. (26244020)
2015
27
Extranodal follicular dendritic cell sarcoma: A clinicopathological report of four cases and a literature review. (25435998)
2015
28
Extranodal follicular dendritic cell sarcoma: a frequently misdiagnosed entity. (25511225)
2015
29
Follicular dendritic cell sarcoma with atypical features surrounding undescended testis: description of a rare case. (25889780)
2015
30
Extranodal follicular dendritic cell sarcoma involving tonsil. (26712678)
2015
31
Follicular dendritic cell sarcoma of mediastinum: a key role of radiotherapy in a multidisciplinary approach. (26638926)
2015
32
Follicular dendritic cell sarcoma with extensive lymph node involvement: A case report. (26171038)
2015
33
Paraneoplastic pemphigus associated with follicular dendritic cell sarcoma: report of a case and review of literature. (26722384)
2015
34
Follicular Dendritic Cell Sarcoma of Lymph Node: A report of a Patient with Chronic Myeloid Leukemia Treated with Imatinib. (26261702)
2015
35
High-risk follicular dendritic cell sarcoma of the tonsil mimicking nasopharyngeal carcinoma. (27003778)
2015
36
Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review. (25621026)
2015
37
Intraperitoneal follicular dendritic cell sarcoma: role of chemotherapy and bone marrow allotransplantation in locally advanced disease? (25698886)
2015
38
Resection is an effective treatment for recurrent follicular dendritic cell sarcoma from retroperitoneum: unusual presentation of a rare tumor. (26221397)
2015
39
Retroperitoneal and mediastinal follicular dendritic cell sarcoma: report of 3 cases with review of literature. (26639109)
2015
40
A rare case of follicular dendritic cell sarcoma with pseudochylous effusion and review of literature from India. (25825580)
2015
41
Follicular dendritic cell sarcoma of the head and neck: Case report, literature review, and pooled analysis of 97 cases. (25917851)
2015
42
Clinical and pathological features of head and neck follicular dendritic cell sarcoma. (25831474)
2015
43
Extranodal follicular dendritic cell sarcoma of the soft palate: a case report. (25674273)
2014
44
Follicular Dendritic Cell Sarcoma Presenting As a Thyroid Mass. (24663046)
2014
45
Recalcitrant paraneoplastic pemphigus associated with follicular dendritic cell sarcoma: response to prolonged rituximab and ciclosporin therapy. (25367731)
2014
46
Mediastinal follicular dendritic cell sarcoma with paraneoplastic pemphigus. (25406405)
2014
47
Follicular dendritic cell sarcoma of the stomach: case report and review of the literature. (25489266)
2014
48
Clinicopathologic characteristics of inflammatory pseudotumor-like follicular dendritic cell sarcoma. (24966952)
2014
49
FDG PET/CT in follicular dendritic cell sarcoma with extensive peritoneal involvement. (24476636)
2014
50
Right pneumonectomy for resection of a posterior mediastinal follicular dendritic cell sarcoma arising from Castleman's disease. (24694448)
2014

Variations for Follicular Dendritic Cell Sarcoma

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Expression for genes affiliated with Follicular Dendritic Cell Sarcoma

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Search GEO for disease gene expression data for Follicular Dendritic Cell Sarcoma.

Pathways for genes affiliated with Follicular Dendritic Cell Sarcoma

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GO Terms for genes affiliated with Follicular Dendritic Cell Sarcoma

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Cellular components related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1desmosomeGO:003005710.3DSG1, DSP
2cytoplasmic side of plasma membraneGO:000989810.1DSG1, KIT
3extracellular matrixGO:00310129.9CLU, DSG1, DSP
4cell-cell junctionGO:00059119.7DSG1, DSP, KIT
5extracellular exosomeGO:00700628.7CLU, CR1, CR2, DSG1, DSP, FCER2
6plasma membraneGO:00058867.3CD68, CR1, CR2, DSG1, DSP, FCER2

Biological processes related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1complement receptor mediated signaling pathwayGO:00024309.8CR1, CR2
2complement activation, classical pathwayGO:00069589.7CLU, CR1, CR2

Molecular functions related to Follicular Dendritic Cell Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1virus receptor activityGO:00016189.8CR1, CR2

Sources for Follicular Dendritic Cell Sarcoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet