MCID: FLL037
MIFTS: 36

Follicular Lymphoma malady

Cancer diseases, Immune diseases categories

Summaries for Follicular Lymphoma

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63Wikipedia, 32MalaCards
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Wikipedia:63 Follicular lymphoma is the most common of the indolent non-Hodgkin\'s lymphomas, and the... more...

MalaCards: Follicular Lymphoma, also known as lymphoma, follicular, is related to leukemia and chronic lymphocytic leukemia. An important gene associated with Follicular Lymphoma is BCL2 (B-cell CLL/lymphoma 2), and among its related pathways are PEDF Induced Signaling and TNF Signaling. The drug ibritumomab tiuxetan and the compounds bcma and rituximab have been mentioned in the context of this disorder. Affiliated tissues include b cells and bone, and related mouse phenotype immune system.

Aliases & Classifications for Follicular Lymphoma

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42NIH Rare Diseases, 30LifeMap Discovery™, 60UMLS, 44Novoseek, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Immune diseases


Aliases & Descriptions:

follicular lymphoma 42 30
lymphoma, follicular 42 60
lymphoma follicular 44


External Ids:

ICD1025 C82

Related Diseases for Follicular Lymphoma

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Sources:
17GeneCards, 18GeneDecks
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Diseases in the Follicular Lymphoma family:

Follicular Lymphoma 1

Diseases related to Follicular Lymphoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 116)
idRelated DiseaseScoreTop Affiliating Genes
1leukemia30.7AICDA, CD27, IL3RA, BCL6, BCL2
2chronic lymphocytic leukemia30.6TNFRSF17, IGHM, AICDA, CD70, CD27, IL3RA
3mantle cell lymphoma30.6BCL2, BCL6
4burkitt's lymphoma30.6BCL2, BCL6
5hodgkin's lymphoma30.4IGHM, AICDA, CD70, IL3RA, BCL6, BCL2
6lymphoblastic leukemia30.3P2RY8
7central nervous system lymphoma30.3BCL6
8gastric lymphoma30.3BCL6
9non-hodgkin lymphoma30.2TNFRSF17, AICDA, CD70, CD27, FCGR3A, KRBOX4
10diffuse large b-cell lymphoma10.7
11gastrointestinal lymphoma10.6
12bone lymphoma10.5
13duodenitis10.5
14pediatric lymphoma10.4
15adult lymphoma10.4
16colon lymphoma10.4
17sarcoma10.4
18composite lymphoma10.3
19pemphigus10.3
20progressive multifocal leukoencephalopathy10.3
21follicular dendritic cell sarcoma10.2
22breast lymphoma10.2
23dendritic cell sarcoma10.2
24lymphoma, follicular, somatic10.2
25rectum lymphoma10.1
26thyroid lymphoma10.1
27protein-losing enteropathy10.1
28follicular mucinosis10.1
29retroperitoneal lymphoma10.1
30splenic marginal zone lymphoma10.1
31small intestine lymphoma10.1
32endometrial carcinoma10.1
33eosinophilia10.1
34mediastinitis10.1
35psoriasis10.1
36thyroiditis10.1
37primary effusion lymphoma10.1
38lymphoma, small cleaved-cell, follicular10.1
39lymphomatoid granulomatosis10.1
40follicular lymphoma 110.1
41diffuse large b-cell lymphoma with chronic inflammation10.1
42myeloma10.0TNFRSF17, IGHM, CD27, BCL6, BCL2
43ipex syndrome10.0IGHM, AICDA, CD70, CD27, FCGR3A, BCL6
44systemic lupus erythematosus10.0TNFRSF17, IGHM, CD70, CD27, FCGR3A
45rheumatoid arthritis10.0TNFRSF17, IGHM, CD70, CD27, FCGR3A
46b-cell chronic lymphocytic leukemia10.0BCL2, CD27, IGHM
47malt lymphoma10.0BCL2, BCL6, IGHM
48plasmacytoma10.0AICDA, CD27, BCL6
49b-cell lymphomas10.0IGHM, AICDA, BCL6, BCL2
50lymphoma, diffuse large cell10.0KRBOX4, BCL6, BCL2

Graphical network of the top 20 diseases related to Follicular Lymphoma:



Diseases related to follicular lymphoma

Clinical Features for Follicular Lymphoma

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Drugs & Therapeutics for Follicular Lymphoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 30LifeMap Discovery™, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Follicular Lymphoma

Drug clinical trials:

Search ClinicalTrials for Follicular Lymphoma

Search NIH Clinical Center for Follicular Lymphoma

Search CenterWatch for Follicular Lymphoma

Inferred drug relations via UMLS60/NDF-RT40:

Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Follicular Lymphoma cell therapies at LifeMap Discovery.

Genetic Tests for Follicular Lymphoma

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Anatomical Context for Follicular Lymphoma

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32MalaCards
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MalaCards organs/tissues related to Follicular Lymphoma:

32
B cells, Bone

Animal Models for Follicular Lymphoma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Follicular Lymphoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000538710.9BCL2, BCL6, FCGR3A, CD27, CD70, AICDA

Publications for Follicular Lymphoma

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Genetic Variations for Follicular Lymphoma

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Expression for genes affiliated with Follicular Lymphoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Follicular Lymphoma

Search GEO for disease gene expression data for Follicular Lymphoma.

Pathways for genes affiliated with Follicular Lymphoma

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Sources:
51QIAGEN, 29KEGG, 55SinoBiological, 52R&D Systems, 37NCBI BioSystems Database, 12EMD Millipore
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Compounds for genes affiliated with Follicular Lymphoma

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank
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Compounds related to Follicular Lymphoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1bcma4410.6CD27, TNFRSF17
2rituximab44 49 1112.3BCL2, BCL6, FCGR3A

GO Terms for genes affiliated with Follicular Lymphoma

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Sources:
16Gene Ontology
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Biological processes related to Follicular Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of immune responseGO:05077610.6BCL6, FCGR3A, IGKV1-5
2extrinsic apoptotic signaling pathwayGO:09719110.6CD27, CD70
3negative regulation of cell growthGO:03030810.5BCL2, BCL6, ZC3H12D
4immune responseGO:00695510.4IGHM, IGKV1-5, CD70, FCGR3A

Products for genes affiliated with Follicular Lymphoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Follicular Lymphoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet