MCID: FDL002
MIFTS: 41

Food Allergy malady

Immune diseases category

Summaries for Food Allergy

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MedlinePlus:32 Food allergy is an abnormal response to a food triggered by your body's immune system. in adults, the foods that most often trigger allergic reactions include fish, shellfish, peanuts, and tree nuts, such as walnuts. problem foods for children can include eggs, milk, peanuts, tree nuts, soy, and wheat. symptoms of food allergy include itching or swelling in your mouth vomiting, diarrhea, or abdominal cramps and pain hives or eczema tightening of the throat and trouble breathing drop in blood pressure your health care provider may use a detailed history, elimination diet, and skin and blood tests to diagnose a food allergy. when you have food allergies, you must be prepared to treat an accidental exposure. wear a medical alert bracelet or necklace, and carry an auto-injector device containing epinephrine (adrenaline). you can only prevent the symptoms of food allergy by avoiding the food. after you and your health care provider have identified the foods to which you are sensitive, you must remove them from your diet. nih: national institute of allergy and infectious diseases

MalaCards based summary: Food Allergy, also known as food hypersensitivity, is related to asthma and atopic dermatitis. An important gene associated with Food Allergy is RNASE3 (ribonuclease, RNase A family, 3), and among its related pathways is Allograft rejection. The drugs cromolyn sodium and cromolyn and the compounds anti-fungal and tele-methylhistamine have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and t cells, and related mouse phenotype immune system.

Disease Ontology:9 A hypersensitivity reaction type i disease that is an abnormal response to a food, triggered by the body's immune system.

Wikipedia:63 A food allergy is an adverse immune response to certain kinds of food. more...

Aliases & Classifications for Food Allergy

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Food Allergy, Aliases & Descriptions:

Name: Food Allergy 9 11 32 60
Food Hypersensitivity 9
 
Allergy Food 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Immune diseases


External Ids:

Disease Ontology9 DOID:3044
MeSH33 D005512

Related Diseases for Food Allergy

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Diseases related to Food Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idRelated DiseaseScoreTop Affiliating Genes
1asthma31.4EPX, RNASE3
2atopic dermatitis31.2RNASE3, EPX, MS4A2
3atopy31.0RNASE3, EPX, MS4A2
4collagenous colitis31.0RNASE3
5allergic rhinitis30.6EPX, RNASE3
6rhinitis30.6RNASE3, EPX, MS4A2
7eosinophilia30.4EPX, RNASE3
8allergic asthma30.2MS4A2, EPX, RNASE3
9colitis30.1CHI3L1, IL32
10dermatitis10.8
11esophagitis10.6
12egg allergy10.5
13chronic rhinitis10.5RNASE3
14eosinophilic gastroenteritis10.4
15gastroenteritis10.4
16blindness10.4
17protein-losing enteropathy10.3
18schistosomiasis10.3RNASE3
19conjunctivitis10.3MS4A2, RNASE3
20bronchitis10.2RNASE3, MS4A2
21aphthous stomatitis10.2
22frey syndrome10.2
23angioedema10.2
24gastritis10.2
25urticaria10.2
26onchocerciasis10.2EPX, RNASE3
27proctitis10.2EPX, RNASE3
28irritable bowel syndrome10.2
29pulmonary eosinophilia10.2RNASE3, EPX
30hypereosinophilic syndrome10.2EPX, RNASE3
31respiratory failure10.1EPX, RNASE3
32gastroesophageal reflux10.1
33celiac disease10.1
34aplastic anemia10.1
35acrodermatitis enteropathica10.1
36scurvy10.1
37loeys-dietz syndrome, type 110.1
38erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper ige10.1
39alopecia10.1
40angioimmunoblastic lymphadenopathy with dysproteinemia10.1
41liver disease10.1
42sinusitis10.1
43anisakiasis10.1
44acrodermatitis10.1
45lymphocytic colitis10.1
46pellagra10.1
47fascioliasis10.1
48peanut allergic reaction10.1
49milk allergic reaction10.1
50adenosine deaminase deficiency10.1

Graphical network of the top 20 diseases related to Food Allergy:



Diseases related to food allergy

Symptoms for Food Allergy

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Drugs & Therapeutics for Food Allergy

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Drug clinical trials:

Search ClinicalTrials for Food Allergy

Search NIH Clinical Center for Food Allergy

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Food Allergy

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Anatomical Context for Food Allergy

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MalaCards organs/tissues related to Food Allergy:

31
Testes, Skin, T cells, Liver, B cells, Small intestine, Breast, Lymph node, Colon, Endothelial, Neutrophil

Animal Models for Food Allergy or affiliated genes

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MGI Mouse Phenotypes related to Food Allergy:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.8CD19, MS4A2, CHI3L1, EPX, DARC

Publications for Food Allergy

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Articles related to Food Allergy:

(show top 50)    (show all 666)
idTitleAuthorsYear
1
Chronic urticaria in a celiac patient: role of food allergy. (25345308)
2014
2
Active management of food allergy: an emerging concept. (25378378)
2014
3
Factors Associated With Reported Food Allergy Tolerance Among US Children. (25363941)
2014
4
Introduction of complementary foods and the relationship to food allergy. (25363920)
2014
5
Food-specific serum immunoglobulin E measurements in children presenting with food allergy. (24468251)
2014
6
Food Allergy, a summary of 8 cases in the UK criminal and civil courts: effective last resort for vulnerable consumers? (25377665)
2014
7
Remission of food allergy by the Janus kinase inhibitor ruxolitinib in mice. (24332884)
2013
8
Gastrointestinal food allergy and intolerance in infants and young children. (24356033)
2013
9
Evaluation of food allergy in patients with atopic dermatitis. (24229818)
2013
10
Improvement of teacher food allergy knowledge in socioeconomically diverse schools after educational intervention. (23899583)
2013
11
Epidemiology of childhood food allergy. (23718236)
2013
12
Food Allergy and Anaphylaxis Meeting (FAAM 2013) Nice, France. 7-9 February 2013. Abstracts. (23902650)
2013
13
Introducing solid food: age of introduction and its effect on risk of food allergy and other atopic diseases. (23851527)
2013
14
Serum basal tryptase may be a good marker for predicting the risk of anaphylaxis in children with food allergy. (24251444)
2013
15
Food allergy testing in infantile eczema: a clinical approach and algorithm. (22686941)
2013
16
Vaccines and immunomodulatory therapies for food allergy. (22090174)
2012
17
High prevalence of food sensitisation in young children with liver disease: a clue to food allergy pathogenesis? (23050587)
2012
18
Goji berries (Lycium barbarum): risk of allergic reactions in individuals with food allergy. (23101309)
2012
19
Role of food allergy in childhood atopic dermatitis. (21679336)
2012
20
Early life precursors, epigenetics, and the development of food allergy. (22777545)
2012
21
Allergic reactions to foods in preschool-aged children in a prospective observational food allergy study. (22732173)
2012
22
Food allergy diagnostic practice in Italian children. (22464643)
2012
23
The predictive value of skin prick testing for challenge-proven food allergy: a systematic review. (22136629)
2012
24
Tolerogenic effects of interferon-gamma with induction of allergen-specific interleukin-10-producing regulatory B cell (Br1) changes in non-IgE-mediated food allergy. (22336594)
2012
25
Transient erythematous rash on the cheek mimicking food allergy. (22182440)
2012
26
Sphingosine-kinase 1 and 2 contribute to oral sensitization and effector phase in a mouse model of food allergy. (22020265)
2012
27
Food allergy: diagnosis and beyond. (22541395)
2012
28
Diagnosis of food allergy: epicutaneous skin tests, in vitro tests, and oral food challenge. (20922509)
2011
29
Food allergy in Lebanon: is sesame seed the "middle eastern" peanut. (23283020)
2011
30
Food allergy in patients with eczema: immediate symptoms are usual, with nuts and tomatoes the major allergens. (21668512)
2011
31
Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel report. (21167411)
2011
32
Eczema and food allergy in an Italian pediatric cohort: no association with TLR-2 and TLR-4 polymorphisms. (20646366)
2010
33
Avoidance or exposure to foods in prevention and treatment of food allergy? (20431373)
2010
34
Food allergy and eosinophilic gastroenteritis and colitis. (20431371)
2010
35
Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. (21134576)
2010
36
Defining the role of food allergy in a population of adult patients with eosinophilic esophagitis. (20887270)
2010
37
Evaluation of TLR4 expression and chosen parameters of oxidative-antioxidative balance in young children with food allergy. (21071337)
2010
38
Maize food allergy: a double-blind placebo-controlled study. (18778272)
2008
39
Food allergy to proteins. (17245088)
2007
40
Food allergy as a new risk factor for scurvy. (17073884)
2006
41
Clinical role of lipid transfer proteins in food allergy. (15672475)
2004
42
Exogenous oestrogen as an alternative to food allergy in the aetiology of angioneurotic oedema. (12505453)
2003
43
Use of an amino-acid-based formula in the treatment of cow's milk protein allergy and multiple food allergy syndrome]. (12012792)
2002
44
Genotype of N-acetyltransferase 2 (NAT2) polymorphism in children with immunoglobulin E-mediated food allergy. (11372006)
2001
45
Increased expression of intercellular adhesion molecule-1 and mucosal adhesion molecule alpha4beta7 integrin in small intestinal mucosa of adult patients with food allergy. (11358431)
2001
46
Food allergy to wheat products: the effect of bread baking and in vitro digestion on wheat allergenic proteins. A study with bread dough, crumb, and crust. (11714375)
2001
47
CagA-positive Helicobacter pylori infection may increase the risk of food allergy development. (10695562)
1999
48
Interleukin-5 immunoreactivity and mRNA expression in gut mucosa from patients with food allergy. (10231331)
1999
49
Microscopic and collagenous colitis in treated celiac disease due to food allergy? (10029639)
1999
50
Oral administration of cromolyn in a patient with protein-losing enteropathy, food allergy, and eosinophilic gastroenteritis. (8170195)
1994

Variations for Food Allergy

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Expression for genes affiliated with Food Allergy

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Search GEO for disease gene expression data for Food Allergy.

Pathways for genes affiliated with Food Allergy

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Pathways related to Food Allergy according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.2MS4A2, EPX, RNASE3

Compounds for genes affiliated with Food Allergy

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Compounds related to Food Allergy according to GeneCards Suite gene sharing:

(show all 29)
idCompoundScoreTop Affiliating Genes
1anti-fungal4310.0CETP, RNASE3
2tele-methylhistamine4310.0RNASE3, EPX
3lte44310.0EPX, RNASE3
4sodium cromoglycate4310.0EPX, RNASE3
5cetirizine43 28 24 1213.0EPX, RNASE3
6sephadex4310.0RNASE3, EPX
7ketotifen43 1211.0EPX, RNASE3
8salmeterol43 49 28 1213.0EPX, RNASE3
9ltc4439.9EPX, RNASE3
10budesonide43 49 1211.9EPX, RNASE3
11salbutamol43 49 28 24 1213.9EPX, RNASE3
12p005439.9RNASE3, EPX
13pgd2439.9EPX, RNASE3
14cytochalasin b439.9EPX, RNASE3
15theophylline43 28 24 1212.8EPX, RNASE3
16dithiothreitol439.8EPX, RNASE3
17leukotriene b443 59 2411.8RNASE3, EPX
18linoleic acid28 43 2411.7CETP, EPX
19p002439.7EPX, RNASE3
20prednisolone43 28 1211.7EPX, RNASE3
21carbohydrates439.6CETP, RNASE3
22formaldehyde43 2410.6EPX, RNASE3
23p003439.5CHI3L1, RNASE3
24heparin43 28 24 1212.5RNASE3, EPX, CETP
25allergens439.2MS4A2, CETP, EPX, RNASE3
26hyaluronic acid43 2410.0CHI3L1, RNASE3
27nitric oxide43 24 1210.8RNASE3, EPX, CHI3L1
28lipid438.6DARC, RNASE3, EPX, CETP, CD19
29tyrosine438.3DARC, RNASE3, EPX, IL32, CD19

GO Terms for genes affiliated with Food Allergy

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Biological processes related to Food Allergy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1defense responseGO:00069529.3IL32, DARC
2inflammatory responseGO:00069548.5MS4A2, CHI3L1, DARC

Products for genes affiliated with Food Allergy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Food Allergy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet