MCID: FDL002
MIFTS: 55

Food Allergy malady

Summaries for Food Allergy

Sources:
8Disease Ontology, 34MedlinePlus, 64Wikipedia, 33MalaCards
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MedlinePlus:34 Food allergy is an abnormal response to a food triggered by your body's immune system. in adults, the foods that most often trigger allergic reactions include fish, shellfish, peanuts, and tree nuts, such as walnuts. problem foods for children can include eggs, milk, peanuts, tree nuts, soy, and wheat. symptoms of food allergy include itching or swelling in your mouth vomiting, diarrhea, or abdominal cramps and pain hives or eczema tightening of the throat and trouble breathing drop in blood pressure your health care provider may use a detailed history, elimination diet, and skin and blood tests to diagnose a food allergy. when you have food allergies, you must be prepared to treat an accidental exposure. wear a medical alert bracelet or necklace, and carry an auto-injector device containing epinephrine (adrenaline). you can only prevent the symptoms of food allergy by avoiding the food. after you and your health care provider have identified the foods to which you are sensitive, you must remove them from your diet. nih: national institute of allergy and infectious diseases

MalaCards: Food Allergy, also known as food hypersensitivity, is related to atopic dermatitis and vasculitis. An important gene associated with Food Allergy is RNASE3 (ribonuclease, RNase A family, 3), and among its related pathways are IL4-mediated signaling events and Allograft rejection. The drugs prednisolone and prednisone and the compounds pge2 and omalizumab have been mentioned in the context of this disorder. Related mouse phenotypes are hematopoietic system and immune system.

Disease Ontology:8 An allergy that is an abnormal response to a food, triggered by the body's immune system.

Wikipedia:64 A food allergy is an adverse immune response to a food protein. They are distinct from other adverse... more...

Aliases & Classifications for Food Allergy

Sources:
8Disease Ontology, 10DISEASES, 34MedlinePlus, 61UMLS, 45Novoseek, 57SNOMED-CT, 35MeSH
See all sources

Aliases & Descriptions:

food allergy 8 10 34 61
food hypersensitivity 8
hypersensitivity 61
allergy food 45


External Ids:

Disease Ontology8 DOID:3044
MeSH35 D005512

Related Diseases for Food Allergy

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Food Allergy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 480)
idRelated DiseaseScoreTop Affiliating Genes
1atopic dermatitis31.0CSN1S1, STAT6, RNASE3
2vasculitis31.0CD14
3asthma31.0IL5, RNASE3, EPX, IGHE
4eosinophilic esophagitis30.8IL5
5atopy30.7CSN1S1, STAT6, IGHE, CD14, EPX, RNASE3
6eosinophilic gastroenteritis30.5CSN1S1, IGHE, IL5
7arthritis30.5S100A8, CSN1S1, FOXP3, STAT6
8peanut allergic reaction30.4IGHE, CSN1S1
9collagenous colitis30.4RNASE3
10allergic asthma30.4STAT6, IGHE, CD14, EPX, RNASE3, IL5
11celiac disease30.3CSN1S1, CCR9
12angioedema30.3IGHE, RNASE3, IL5
13egg allergy30.3IGHE, IL5
14allergic bronchopulmonary aspergillosis30.1IGHE, IL5
15anisakiasis30.1RNASE3, IGHE
16gastroesophageal reflux disease30.1S100A8, CSN1S1
17allergic rhinitis30.1IL5, RNASE3, EPX, IGHE
18urticaria30.1RNASE3, IGHE, CSN1S1
19sinusitis30.1IL5, RNASE3, IGHE
20uveitis30.0CD14
21allergic conjunctivitis30.0IL5, RNASE3, IGHE
22cystic fibrosis29.9S100A8, RNASE3
23churg-strauss syndrome29.9IL5, RNASE3
24bullous pemphigoid29.9IGHE, RNASE3, IL5
25tuberculosis29.9EPX
26bronchiolitis29.8IL5, RNASE3, IGHE
27vernal keratoconjunctivitis29.8IGHE, RNASE3, IL5
28mastocytosis29.8IGHE, IL5
29ulcerative colitis29.8CSN1S1, STAT6, CD14, EPX, RNASE3
30intrinsic asthma29.6IGHE, RNASE3, IL5
31toxocariasis29.6IGHE, RNASE3
32bronchiectasis29.6IGHE, RNASE3
33graves' disease29.6STAT6
34mycosis fungoides29.6IL5
35diphtheria29.6FOXP3, CSN1S1
36wegener's granulomatosis29.6CD14
37adenocarcinoma29.6CSN1S1, S100A8
38abacavir hypersensitivity10.7
39protein-losing enteropathy10.3
40h. pylori infection10.3
41arthus reaction10.2
42idiopathic pulmonary fibrosis10.2
43whiplash10.2
44n syndrome10.2
45eosinophilic enteropathy10.2
46microscopic colitis10.2
47irritable bowel syndrome10.2
48polycythemia vera10.2
49lymphocytic choriomeningitis10.2
50familial hypersensitivity pneumonitis10.2

Graphical network of the top 20 diseases related to Food Allergy:



Diseases related to food allergy

Clinical Features for Food Allergy

Drugs & Therapeutics for Food Allergy

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Genetic Tests for Food Allergy

Anatomical Context for Food Allergy

Animal Models for Food Allergy or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Food Allergy:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053979.8S1PR1, FOXP3, FAIM, STAT6, IGHE, EPX
2MP:00053879.3LGALS9, CCR9, S1PR1, FOXP3, FAIM, STAT6

Publications for Food Allergy

Sources:
51PubMed
See all sources

Articles related to Food Allergy:

(show top 50)    (show all 627)
idTitleAuthorsYear
1
Oral food desensitization in children with IgE-mediated hen's egg allergy: a new protocol with raw hen's egg. (22882430)
2013
2
Epidemiology of childhood food allergy. (23718236)
2013
3
A molecular insight of CTLA-4 in food allergy. (23254121)
2013
4
Food allergy: management, diagnosis and treatment strategies. (23829626)
2013
5
Food allergy among low birthweight children in a national survey. (22322430)
2013
6
Enhancement of CGRP sensory afferent innervation in the gut during the development of food allergy in an experimental murine model. (23261435)
2013
7
State of the art and perspectives in food allergy (part I): diagnosis. (23701559)
2013
8
Protein contact dermatitis and food allergy to mare milk. (23622015)
2013
9
Food allergy and food-based therapies in neurodevelopmental disorders. (24236934)
2013
10
Garlic and onion sensitization among Saudi patients screened for food allergy: a hospital based study. (24250308)
2013
11
Early life precursors, epigenetics, and the development of food allergy. (22777545)
2012
12
Chapter 23: Food allergy. (22794696)
2012
13
Cow's milk anaphylaxis in children first report of Iranian Food Allergy Registry. (22427474)
2012
14
Filaggrin loss-of-function mutations do not predict food allergy over and above the risk of food sensitization among infants. (22964107)
2012
15
Organ-specific symptoms during oral food challenge in children with food allergy. (22846754)
2012
16
Prevalence of self-reported food allergy in Hong Kong children and teens--a population survey. (23393907)
2012
17
Potential mechanisms for the association between fall birth and food allergy. (22515802)
2012
18
Molecular mechanisms of IgE mediated food allergy. (22668720)
2012
19
ICON: food allergy. (22365653)
2012
20
Diagnosis of food allergy: epicutaneous skin tests, in vitro tests, and oral food challenge. (20922509)
2011
21
Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report. (21310308)
2011
22
Oral administration of bacterial lysates attenuates experimental food allergy. (21597300)
2011
23
Food allergy and anaphylaxis meeting 2011 venice, Italy. 17-19 february 2011. Abstracts. (22676900)
2011
24
Food allergy: practical considerations for primary care. (22073492)
2011
25
Online version of the food allergy quality of life questionnaire-adult form: validity, feasibility and cross-cultural comparison. (21395879)
2011
26
Phenotypes of IgE-mediated food allergy in Turkish children. (22221430)
2011
27
Experimental food allergy leads to adipose tissue inflammation, systemic metabolic alterations and weight loss in mice. (21636080)
2011
28
Food allergy. (21349900)
2011
29
Vaccine approaches for food allergy. (21400223)
2011
30
Living with food allergy. (21980692)
2011
31
Diagnosis and assessment of food allergy in children and young people. (21739860)
2011
32
Food allergy in Ghanaian schoolchildren: data on sensitization and reported food allergy. (21109750)
2011
33
Food allergy and eosinophilic esophagitis: learning what to avoid. (20048030)
2010
34
Safety, tolerability, and immunologic effects of a food allergy herbal formula in food allergic individuals: a randomized, double-blinded, placebo-controlled, dose escalation, phase 1 study. (20642207)
2010
35
The role of immunoglobulin E-binding epitopes in the characterization of food allergy. (19568005)
2009
36
Lupin sensitization and clinical allergy in food allergic children in Norway. (18076722)
2008
37
Food allergy and atopy patch tests. (17676240)
2007
38
Wheat IgE-mediated food allergy in European patients: alpha-amylase inhibitors, lipid transfer proteins and low-molecular-weight glutenins. Allergenic molecules recognized by double-blind, placebo-controlled food challenge. (17496422)
2007
39
Food allergy as a new risk factor for scurvy. (17073884)
2006
40
Apple allergy across Europe: how allergen sensitization profiles determine the clinical expression of allergies to plant foods. (16890775)
2006
41
Epsilon germ-line and IL-4 transcripts are expressed in human intestinal mucosa and enhanced in patients with food allergy. (15876314)
2005
42
Molecular basis of pollen-related food allergy: identification of a second cross-reactive IgE epitope on Pru av 1, the major cherry (Prunus avium) allergen. (15330760)
2005
43
Prediction of food allergy by using cord blood IgE levels]. (15059487)
2004
44
Novel plant pathogenesis-related protein family involved in food allergy. (15480331)
2004
45
Clinical importance of cross-reactivity in food allergy. (15126948)
2004
46
Challenge testes for diagnosis and follow-up of children with food allergy]. (12790076)
2003
47
Eosinophil cationic protein in serum of children with food allergy]. (12712820)
2003
48
Glucagon-like peptide-2-enhanced barrier function reduces pathophysiology in a model of food allergy. (12736145)
2003
49
Evaluating the profile of selected cytokines in patients with food allergy and chronic gastritis. (11208468)
2000
50
Copro-eosinophil cationic protein (ECP) in food allergy. (9020432)
1996

Genetic Variations for Food Allergy

Expression for genes affiliated with Food Allergy

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Food Allergy

Search GEO for disease gene expression data for Food Allergy.

Pathways for genes affiliated with Food Allergy

Sources:
38NCBI BioSystems Database, 30KEGG, 12EMD Millipore
See all sources

Compounds for genes affiliated with Food Allergy

Sources:
45Novoseek, 11DrugBank, 29IUPHAR, 24HMDB, 50PharmGKB, 60Tocris Bioscience
See all sources

Compounds related to Food Allergy according to GeneCards/GeneDecks:

(show top 50)    (show all 83)
idCompoundScoreTop Affiliating Genes
1pge24510.8EPX
2omalizumab45 1111.7IGHE, IL5, MS4A2
3tele-methylhistamine4510.7IGHE, EPX, RNASE3
4lte44510.7EPX, RNASE3, IL5
5beclomethasone dipropionate4510.7IL5, RNASE3, IGHE
6toluene diisocyanate4510.7RNASE3, IL5, IGHE
7nedocromil sodium4510.6IGHE, IL5, RNASE3
8unicap4510.6RNASE3, CD14, IGHE, IL5
9sodium cromoglycate4510.6IGHE, EPX, RNASE3, IL5
10cetirizine45 29 11 2413.6IGHE, IL5, RNASE3, EPX
11ketotifen45 1111.6RNASE3, EPX, IGHE, IL5
12budesonide45 50 1112.6IL5, RNASE3, EPX, IGHE
13ovomucoid4510.6IGHE, CSN1S1, IL5
14salbutamol45 50 29 11 2414.6IGHE, EPX, IL5, RNASE3
15salmeterol45 50 29 1113.6IL5, EPX, RNASE3
16pgd24510.6IGHE, IL5, EPX, RNASE3
17praziquantel45 1111.6IGHE, RNASE3, IL5
18fluticasone propionate45 50 60 1113.6STAT6, IGHE, RNASE3, IL5
19azelastine45 1111.6IL5, RNASE3, IGHE
20methacholine45 1111.6RNASE3, IL5, IGHE, CD14
21glucono-delta-lactone4510.6CSN3, CSN1S1
22gliadin4510.6CSN1S1, IGHE, RNASE3
23montelukast45 50 29 1113.6IL5, RNASE3, IGHE
24percoll4510.6IL5, CD14, RNASE3
25heparin45 29 11 2413.6CETP, CD14, CSN1S1, EPX, RNASE3
26ltc44510.6RNASE3, IL5, EPX
27itraconazole45 1111.5CSN1S1, IGHE, IL5
28sodium caseinate4510.5CSN1S1, CSN3
29carbohydrates4510.5IGHE, CSN1S1, CETP, RNASE3, CD14
30lactose45 1111.5IL5, LGALS9, CSN1S1, CSN3
31rennet4510.5CSN1S1, CSN3
32prednisolone45 29 1112.5CD14, EPX, RNASE3, IL5, IGHE, CSN1S1
33cyclosporin a45 29 6012.4RNASE3, FOXP3, CD14, CETP, IL5, IGHE
34p0054510.4EPX, S100A8, RNASE3
35aluminium hydroxide4510.4CSN1S1, IGHE
36polyacrylamide4510.4CSN3, S100A8, CSN1S1, CD14, CETP
37thyroxine45 2411.4CSN1S1, CETP, IL5, IGHE
38urea45 11 2412.4RNASE3, CSN3, CSN1S1, S100A8
39allergens4510.4STAT6, CSN3, IGHE, EPX, RNASE3, IL5
40fmlp4510.4IL5, RNASE3, EPX, CD14
41dexamethasone45 50 29 1113.3RNASE3, EPX, IGHE, STAT6, S100A8, IL5
42creatinine4510.3CSN1S1, RNASE3, EPX, CD14, S100A8, IGHE
43histamine45 29 2412.3IL5, S100A8, CSN1S1, STAT6, IGHE, CD14
44retinoic acid45 2411.2CETP, IL5, RNASE3, CD14, IGHE, S100A8
45anti-fungal4510.2RNASE3, IL5, CETP
46glutamine4510.2CETP, IL5, CD14, CSN1S1, IGHE
47lactate4510.1RNASE3, CD14, CSN1S1, IGHE, EPX
48mometasone furoate45 6011.0RNASE3, IL5
49arginine4510.0CETP, CD14, CSN1S1, IGHE, RNASE3, IL5
50calcium45 50 11 2413.0TMEM37, EPX, RNASE3, LGALS9, CD14, S1PR1

GO Terms for genes affiliated with Food Allergy

Sources:
16Gene Ontology
See all sources

Cellular components related to Food Allergy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.8CETP, LGALS9, IL5, RNASE3, CD14, IGHE

Biological processes related to Food Allergy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of interleukin-5 productionGO:03271410.4EPX, FOXP3
2negative regulation of interleukin-10 productionGO:03269310.3EPX, FOXP3
3positive regulation of interleukin-4 productionGO:03275310.2EPX, FOXP3
4innate immune responseGO:04508710.1MS4A2, CD14, IGHE, STAT6, S100A8
5inflammatory responseGO:0069549.9S100A8, CD14, IL5, MS4A2

Products for genes affiliated with Food Allergy

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Food Allergy

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet