MCID: FDL002
MIFTS: 52

Food Allergy malady

Immune diseases category

Summaries for Food Allergy

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Sources:
9Disease Ontology, 35MedlinePlus, 66Wikipedia, 34MalaCards
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MedlinePlus:35 Food allergy is an abnormal response to a food triggered by your body's immune system. in adults, the foods that most often trigger allergic reactions include fish, shellfish, peanuts, and tree nuts, such as walnuts. problem foods for children can include eggs, milk, peanuts, tree nuts, soy, and wheat. symptoms of food allergy include itching or swelling in your mouth vomiting, diarrhea, or abdominal cramps and pain hives or eczema tightening of the throat and trouble breathing drop in blood pressure your health care provider may use a detailed history, elimination diet, and skin and blood tests to diagnose a food allergy. when you have food allergies, you must be prepared to treat an accidental exposure. wear a medical alert bracelet or necklace, and carry an auto-injector device containing epinephrine (adrenaline). you can only prevent the symptoms of food allergy by avoiding the food. after you and your health care provider have identified the foods to which you are sensitive, you must remove them from your diet. nih: national institute of allergy and infectious diseases

MalaCards: Food Allergy, also known as food hypersensitivity, is related to atopic dermatitis and asthma. An important gene associated with Food Allergy is RNASE3 (ribonuclease, RNase A family, 3), and among its related pathways is Allograft rejection. The drugs cromolyn sodium and cromolyn and the compounds anti-fungal and tele-methylhistamine have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and t cells, and related mouse phenotype immune system.

Disease Ontology:9 A hypersensitivity reaction type i disease that is an abnormal response to a food, triggered by the body's immune system.

Wikipedia:66 A food allergy is an adverse immune response to a food protein. more...

Aliases & Classifications for Food Allergy

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Sources:
9Disease Ontology, 11DISEASES, 46Novoseek, 35MedlinePlus, 63UMLS, 59SNOMED-CT, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Immune diseases


Aliases & Descriptions:

food allergy 9 11 35 63
food hypersensitivity 9
hypersensitivity 63
allergy food 46


External Ids:

Disease Ontology9 DOID:3044
MeSH36 D005512

Related Diseases for Food Allergy

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Food Allergy:



Diseases related to food allergy

Symptoms for Food Allergy

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Drugs & Therapeutics for Food Allergy

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Genetic Tests for Food Allergy

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Anatomical Context for Food Allergy

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Sources:
34MalaCards
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MalaCards organs/tissues related to Food Allergy:

34
Testes, Skin, T cells, Liver, B cells, Small intestine, Breast, Colon, Endothelial

Animal Models for Food Allergy or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Food Allergy:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.8CD19, MS4A2, CHI3L1, EPX, DARC

Publications for Food Allergy

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Sources:
53PubMed
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Articles related to Food Allergy:

(show top 50)    (show all 619)
idTitleAuthorsYear
1
Remission of food allergy by the Janus kinase inhibitor ruxolitinib in mice. (24332884)
2013
2
Gastrointestinal food allergy and intolerance in infants and young children. (24356033)
2013
3
Evaluation of food allergy in patients with atopic dermatitis. (24229818)
2013
4
Improvement of teacher food allergy knowledge in socioeconomically diverse schools after educational intervention. (23899583)
2013
5
Epidemiology of childhood food allergy. (23718236)
2013
6
Food Allergy and Anaphylaxis Meeting (FAAM 2013) Nice, France. 7-9 February 2013. Abstracts. (23902650)
2013
7
Introducing solid food: age of introduction and its effect on risk of food allergy and other atopic diseases. (23851527)
2013
8
Serum basal tryptase may be a good marker for predicting the risk of anaphylaxis in children with food allergy. (24251444)
2013
9
Food allergy testing in infantile eczema: a clinical approach and algorithm. (22686941)
2013
10
A molecular insight of CTLA-4 in food allergy. (23254121)
2013
11
Vaccines and immunomodulatory therapies for food allergy. (22090174)
2012
12
High prevalence of food sensitisation in young children with liver disease: a clue to food allergy pathogenesis? (23050587)
2012
13
Goji berries (Lycium barbarum): risk of allergic reactions in individuals with food allergy. (23101309)
2012
14
Role of food allergy in childhood atopic dermatitis. (21679336)
2012
15
Early life precursors, epigenetics, and the development of food allergy. (22777545)
2012
16
Allergic reactions to foods in preschool-aged children in a prospective observational food allergy study. (22732173)
2012
17
Food allergy diagnostic practice in Italian children. (22464643)
2012
18
The predictive value of skin prick testing for challenge-proven food allergy: a systematic review. (22136629)
2012
19
Tolerogenic effects of interferon-gamma with induction of allergen-specific interleukin-10-producing regulatory B cell (Br1) changes in non-IgE-mediated food allergy. (22336594)
2012
20
Transient erythematous rash on the cheek mimicking food allergy. (22182440)
2012
21
Sphingosine-kinase 1 and 2 contribute to oral sensitization and effector phase in a mouse model of food allergy. (22020265)
2012
22
Food allergy: diagnosis and beyond. (22541395)
2012
23
Food allergy prevalence: new possibilities for therapy and prevention. (23188465)
2012
24
Diagnosis of food allergy: epicutaneous skin tests, in vitro tests, and oral food challenge. (20922509)
2011
25
Food allergy in Lebanon: is sesame seed the "middle eastern" peanut. (23283020)
2011
26
Food allergy in patients with eczema: immediate symptoms are usual, with nuts and tomatoes the major allergens. (21668512)
2011
27
Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel report. (21167411)
2011
28
Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel Report. (21215925)
2011
29
Food allergy: an increasing problem for the elderly. (20551623)
2011
30
Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report. (21310308)
2011
31
Eczema and food allergy in an Italian pediatric cohort: no association with TLR-2 and TLR-4 polymorphisms. (20646366)
2010
32
Avoidance or exposure to foods in prevention and treatment of food allergy? (20431373)
2010
33
Food allergy and eosinophilic gastroenteritis and colitis. (20431371)
2010
34
Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. (21134576)
2010
35
Defining the role of food allergy in a population of adult patients with eosinophilic esophagitis. (20887270)
2010
36
Evaluation of TLR4 expression and chosen parameters of oxidative-antioxidative balance in young children with food allergy. (21071337)
2010
37
Immunotherapy in food allergy. (20543886)
2010
38
Maize food allergy: a double-blind placebo-controlled study. (18778272)
2008
39
Food allergy to proteins. (17245088)
2007
40
Food allergy as a new risk factor for scurvy. (17073884)
2006
41
Clinical role of lipid transfer proteins in food allergy. (15672475)
2004
42
Exogenous oestrogen as an alternative to food allergy in the aetiology of angioneurotic oedema. (12505453)
2003
43
Use of an amino-acid-based formula in the treatment of cow's milk protein allergy and multiple food allergy syndrome]. (12012792)
2002
44
Genotype of N-acetyltransferase 2 (NAT2) polymorphism in children with immunoglobulin E-mediated food allergy. (11372006)
2001
45
Increased expression of intercellular adhesion molecule-1 and mucosal adhesion molecule alpha4beta7 integrin in small intestinal mucosa of adult patients with food allergy. (11358431)
2001
46
Food allergy to wheat products: the effect of bread baking and in vitro digestion on wheat allergenic proteins. A study with bread dough, crumb, and crust. (11714375)
2001
47
CagA-positive Helicobacter pylori infection may increase the risk of food allergy development. (10695562)
1999
48
Interleukin-5 immunoreactivity and mRNA expression in gut mucosa from patients with food allergy. (10231331)
1999
49
Microscopic and collagenous colitis in treated celiac disease due to food allergy? (10029639)
1999
50
Oral administration of cromolyn in a patient with protein-losing enteropathy, food allergy, and eosinophilic gastroenteritis. (8170195)
1994

Variations for Food Allergy

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Expression for genes affiliated with Food Allergy

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Food Allergy

Search GEO for disease gene expression data for Food Allergy.

Pathways for genes affiliated with Food Allergy

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Sources:
51PathCards, 31KEGG, 39NCBI BioSystems Database, 54QIAGEN
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Pathways related to Food Allergy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.2MS4A2, EPX, RNASE3

Compounds for genes affiliated with Food Allergy

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Sources:
46Novoseek, 30IUPHAR, 25HMDB, 12DrugBank, 52PharmGKB, 62Tocris Bioscience
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Compounds related to Food Allergy according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1anti-fungal4610.0CETP, RNASE3
2tele-methylhistamine4610.0RNASE3, EPX
3lte44610.0EPX, RNASE3
4sodium cromoglycate4610.0EPX, RNASE3
5cetirizine46 30 25 1213.0EPX, RNASE3
6sephadex4610.0RNASE3, EPX
7ketotifen46 1211.0EPX, RNASE3
8salmeterol46 52 30 1213.0EPX, RNASE3
9ltc4469.9EPX, RNASE3
10budesonide46 52 1211.9EPX, RNASE3
11salbutamol46 52 30 25 1213.9EPX, RNASE3
12p005469.9RNASE3, EPX
13pgd2469.9EPX, RNASE3
14cytochalasin b469.9EPX, RNASE3
15theophylline46 30 25 1212.8EPX, RNASE3
16dithiothreitol469.8EPX, RNASE3
17leukotriene b446 62 2511.8RNASE3, EPX
18linoleic acid30 46 2511.7CETP, EPX
19p002469.7EPX, RNASE3
20prednisolone46 30 1211.7EPX, RNASE3
21carbohydrates469.6CETP, RNASE3
22formaldehyde46 2510.6EPX, RNASE3
23p003469.5CHI3L1, RNASE3
24heparin46 30 25 1212.5RNASE3, EPX, CETP
25allergens469.2MS4A2, CETP, EPX, RNASE3
26hyaluronic acid46 2510.0CHI3L1, RNASE3
27nitric oxide46 25 1210.8RNASE3, EPX, CHI3L1
28lipid468.6DARC, RNASE3, EPX, CETP, CD19
29tyrosine468.3DARC, RNASE3, EPX, IL32, CD19

GO Terms for genes affiliated with Food Allergy

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Sources:
17Gene Ontology
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Biological processes related to Food Allergy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1defense responseGO:0069529.3IL32, DARC
2inflammatory responseGO:0069548.5MS4A2, CHI3L1, DARC

Products for genes affiliated with Food Allergy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Food Allergy

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet