MCID: FDB001
MIFTS: 45

Foodborne Botulism malady

Categories: Rare diseases, Infectious diseases, Neuronal diseases

Aliases & Classifications for Foodborne Botulism

About this section
Sources:
2CDC, 11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 38MedlinePlus, 39MeSH, 40MESH via Orphanet, 45NCIt, 48NIH Rare Diseases, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Foodborne Botulism:

Name: Foodborne Botulism 11 48 54 13
Botulism 11 48 54 50 38 2 39 13
Wound Botulism 48 68
Intoxication with Clostridium Botulinum Toxin 11
Food Poisoning Due to Clostridium Botulinum 11
 
Infection Due to Clostridium Botulinum 11
Intoxication Botulism 54
Botulism, Infantile 68
Botulism Poisoning 11
Infant Botulism 48

Characteristics:

Orphanet epidemiological data:

54
botulism:
Prevalence: <1/1000000 (Europe),<1/1000000 (Worldwide),1-9/1000000 (France),1-9/1000000 (United States); Age of onset: All ages; Age of death: any age
foodborne botulism:
Prevalence: 1-9/1000000 (Europe),1-9/1000000 (Romania); Age of onset: All ages; Age of death: any age

Classifications:



External Ids:

Disease Ontology11 DOID:0050352, DOID:11976
ICD1030 A05.1
MeSH39 D001906
NCIt45 C84599
MESH via Orphanet40 D001906
UMLS via Orphanet69 C0006057, C1739094
ICD10 via Orphanet31 A05.1

Summaries for Foodborne Botulism

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MedlinePlus:38 Botulism is a rare but serious illness. the cause is a toxin (poison) made by a bacterium called clostridium botulinum. it occurs naturally in soil. there are several kinds of botulism. foodborne botulism comes from eating foods contaminated with the toxin. wound botulism happens when a wound infected with the bacteria makes the toxin. it is more common in heroin users. infant botulism happens when a baby consumes the spores of the bacteria from soil or honey. all forms can be deadly and are medical emergencies. symptoms include double or blurred vision, drooping eyelids, slurred speech, difficulty swallowing, dry mouth, and muscle weakness. treatment may include antitoxins, intensive medical care, or surgery of infected wounds. to prevent botulism: be very careful when canning foods at home do not let babies eat honey get prompt medical care for infected wounds centers for disease control and prevention

MalaCards based summary: Foodborne Botulism, also known as botulism, is related to infant botulism and wound botulism, and has symptoms including xerostomia, abnormality of the pupil and diplopia. An important gene associated with Foodborne Botulism is SNAP25 (Synaptosome Associated Protein 25), and among its related pathways are Effects of Botulinum toxin and Uptake and actions of bacterial toxins. Affiliated tissues include spinal cord, and related mouse phenotype normal.

Disease Ontology:11 A primary bacterial infectious disease that involves intoxication caused by botulinum neurotoxins (BoNTA, B, E and F) located in neuromuscular junction, resulting in descending muscle paralysis, has material basis in Clostridium botulinum A, has material basis in Clostridium botulinum B, has material basis in Clostridium botulinum E and has material basis in Clostridium botulinum F.

Wikipedia:71 Botulism is a rare and potentially fatal illness caused by a toxin, produced by the bacterium... more...

Related Diseases for Foodborne Botulism

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Graphical network of diseases related to Foodborne Botulism:



Diseases related to foodborne botulism

Symptoms & Phenotypes for Foodborne Botulism

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Symptoms:

 11 (show all 6)
  • blurred vision
  • diplopia
  • dysarthria
  • dysphonia
  • dysphagia
  • descending muscle paralysis

Human phenotypes related to Foodborne Botulism:

 64 54 (show all 29)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 xerostomia64 54 hallmark (90%) Very frequent (99-80%) HP:0000217
2 abnormality of the pupil64 hallmark (90%) HP:0000615
3 diplopia64 54 hallmark (90%) Very frequent (99-80%) HP:0000651
4 abdominal pain64 54 hallmark (90%) Very frequent (99-80%) HP:0002027
5 neurological speech impairment64 hallmark (90%) HP:0002167
6 diaphragmatic paralysis64 54 hallmark (90%) Very frequent (99-80%) HP:0006597
7 cranial nerve paralysis64 54 hallmark (90%) Very frequent (99-80%) HP:0006824
8 feeding difficulties in infancy64 hallmark (90%) HP:0008872
9 cerebral palsy64 54 hallmark (90%) Very frequent (99-80%) HP:0100021
10 ptosis64 54 hallmark (90%) Very frequent (99-80%) HP:0000508
11 diarrhea64 54 hallmark (90%) Occasional (29-5%) HP:0002014
12 constipation64 54 hallmark (90%) Frequent (79-30%) HP:0002019
13 hemiplegia/hemiparesis64 hallmark (90%) HP:0004374
14 nausea and vomiting64 54 typical (50%) Frequent (79-30%) HP:0002017
15 respiratory insufficiency64 54 typical (50%) Frequent (79-30%) HP:0002093
16 arrhythmia64 54 typical (50%) Frequent (79-30%) HP:0011675
17 abnormal renal physiology64 typical (50%) HP:0012211
18 sudden cardiac death64 occasional (7.5%) HP:0001645
19 urinary retention54 Frequent (79-30%)
20 dysarthria54 Very frequent (99-80%)
21 dysphagia54 Very frequent (99-80%)
22 muscle flaccidity54 Very frequent (99-80%)
23 mydriasis54 Very frequent (99-80%)
24 diaphragmatic weakness54 Occasional (29-5%)
25 fatigue54 Very frequent (99-80%)
26 muscle weakness54 Very frequent (99-80%)
27 respiratory insufficiency due to muscle weakness54 Frequent (79-30%)
28 paralysis54 Very frequent (99-80%)
29 cardiorespiratory arrest54 Occasional (29-5%)

MGI Mouse Phenotypes related to Foodborne Botulism according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028737.4DPAGT1, GP2, HAS1, PAX3, SNAP25, SYT1

Drugs & Therapeutics for Foodborne Botulism

About this section

Drugs for Foodborne Botulism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AcetylcholineapprovedPhase 4, Phase 177651-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
2
Triamcinoloneapproved, vet_approvedPhase 4482124-94-731307
Synonyms:
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione
11.Beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11.beta.,16.alpha.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
124-94-7
4-08-00-03629 (Beilstein Handbook Reference)
83474-03-7
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-16-alpha-hydroxyprednisolone
9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahy
9.Alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-d
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-Fluoro-16alpha-hydroxyprednisolone
9α-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-16α-hydroxyprednisolone
AC-2072
AC1L1LDH
AC1Q5HJC
Adcortyl
Aristocort
Aristocort A
Aristocort Tablets
Aristogel
Aristospan
Azmacort
BPBio1_000154
BRD-K77554836-001-03-3
BRN 2341955
BSPBio_000140
Bio-0662
C21H27FO6
CHEMBL1451
CID31307
CL 19823
Celeste
Cinolone
Cinolone-T
D00385
D014221
DB00620
Delphicort
EINECS 204-718-7
EU-0101179
Fluoxiprednisolone
Fluoxyprednisolone
Flutex
Fougera
HMS1568G22
HMS2090D12
HSDB 3194
Kenacort
Kenacort (TN)
Kenacort-A
Kenacort-AG
Kenacort-Ag
Kenalog
Kenalog in Orabase
Kenalog-10
Kenalog-40
Kenalog-H
LS-698
Ledercort
Lopac0_001179
 
MLS000028542
MLS001066543
MLS002695935
MolPort-002-528-981
Mycolog
NCGC00021580-03
NCGC00021580-04
NCGC00021580-05
NCGC00021580-06
NCGC00021580-07
NCI60_000750
NSC 13397
NSC13397
Nasacort
Nasacort Aq
Nasacort Hfa
Omcilon
Omicilon
Oracort
Oralone
Orion
Polcortolon
Pregna-1,4-diene-3,20-dio
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy- (8CI)
Prestwick0_000120
Prestwick1_000120
Prestwick2_000120
Prestwick3_000120
Prestwick_438
Rodinolone
S1933_Selleck
SK-Triamcinolone
SMP1_000300
SMR000058333
SPBio_002079
Sk-Triamcinolone
T6376_SIGMA
TRIAMCINOLONE (SEE ALSO TRIAMCINOLONE ACETONIDE (76-25-5) AND TRIAMCINOLONE DIACETATE (67-78-7))
Tiamcinolonum
Tiamcinolonum [INN-Latin]
Tri-Nasal
Triacet
Triacort
Triam-Tablinen
Triamcet
Triamcinalone
Triamcinlon
Triamcinolon
Triamcinolona
Triamcinolona [INN-Spanish]
Triamcinolone (JP15/USP/INN)
Triamcinolone [USAN:INN:BAN:JAN]
Triamcinolone acetonide
Triamcinolone diacetate
Triamcinolone hexacetonide
Triamcinolonum
Triamcinolonum [INN]
Triatex
Tricortale
Triderm
Trilone
Tristoject
Trymex
UNII-1ZK20VI6TY
Vetalog
Volon
Volon A
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ GQ
ZINC03882036
droxypregna-1,4-diene-3,20-dione
ione
nchembio.2007.53-comp7
triamcinolone
3
Lidocaineapproved, vet_approvedPhase 41226137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
4Peripheral Nervous System AgentsPhase 422776
5Neurotransmitter AgentsPhase 4, Phase 117734
6Neuromuscular AgentsPhase 41129
7AntitoxinsPhase 4, Phase 112
8onabotulinumtoxinAPhase 4626
9incobotulinumtoxinAPhase 4635
10Botulinum ToxinsPhase 4, Phase 1669
11abobotulinumtoxinAPhase 4626
12Botulinum Toxins, Type APhase 4630
13Cholinergic AgentsPhase 4, Phase 13846
14Botulinum AntitoxinPhase 4, Phase 16
15Pharmaceutical SolutionsPhase 47793
16Immunosuppressive AgentsPhase 412770
17triamcinolone acetonidePhase 4482
18Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 412767
19Triamcinolone hexacetonidePhase 4482
20Triamcinolone diacetatePhase 4482
21Sodium Channel BlockersPhase 41515
22HormonesPhase 413979
23Anti-Arrhythmia AgentsPhase 42969
24Anesthetics, LocalPhase 43272
25AnestheticsPhase 49001
26Anti-Inflammatory AgentsPhase 410355
27Central Nervous System DepressantsPhase 412806
28glucocorticoidsPhase 44920
29Diuretics, Potassium SparingPhase 41827
30Hormone AntagonistsPhase 412778
31
4-AminopyridineapprovedPhase 2, Phase 368504-24-51727
Synonyms:
.gamma.-Aminopyridine
275875_ALDRICH
36687_FLUKA
36687_RIEDEL
4 AP
4 Aminopyridine
4 Aminopyridine Sustained Release
4-AP
4-Aminopyridine
4-Aminopyridine 10
4-Aminopyridine Sustained Release
4-Pyridinamine
4-Pyridylamine
4-aminopyridine
5-22-09-00106 (Beilstein Handbook Reference)
504-24-5
A 0152
A0414
A78403_ALDRICH
AB1004971
AC-907/25014071
AC1L1C3R
AC1Q52BM
AI3-52547
AKOS000119896
Amaya
Amino-4 pyridine
Amino-4-Pyridine
Ampydin
Ampyra
Avitrol
Avitrol 200
BB_SC-6974
BRN 0105782
BSPBio_001562
Bio1_000353
Bio1_000842
Bio1_001331
Bio2_000282
Bio2_000762
C13728
C5H6N2
CHEBI:34385
CHEMBL284348
CID1727
Caswell No. 038
Compound 1861
D015761
D04127
Dalfampridine
DivK1c_000572
EINECS 207-987-9
EL-970
EPA Pesticide Chemical Code 069201
EU-0100032
FT-0083754
Fampridina
Fampridine
Fampridine (USAN/INN)
Fampridine SR
Fampridine [USAN:INN]
Fampridine-PR
Fampridine-SR
Fampridinum
HC150041
HMS1361O04
HMS1791O04
HMS1921H15
HMS1989O04
HMS2092F05
HMS501M14
HSDB 6037
IDI1_000572
IDI1_034032
InChI=1/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7
KBio1_000572
 
KBio2_000282
KBio2_000635
KBio2_002850
KBio2_003203
KBio2_005418
KBio2_005771
KBio3_000563
KBio3_000564
KBio3_001888
KBioGR_000282
KBioGR_001505
KBioSS_000282
KBioSS_000635
LS-130202
Lopac-A-0152
Lopac0_000032
MLS000069400
Mi-W-3
MolPort-000-146-022
N07XX07
NCGC00015009-01
NCGC00015009-03
NCGC00015009-12
NCGC00024890-01
NCGC00024890-02
NCGC00024890-03
NCGC00024890-04
NCGC00024890-05
NCGC00024890-06
NCGC00024890-07
NCGC00024890-08
NCGC00024890-09
NCGC00024890-10
NINDS_000572
NSC 15041
NSC15041
Neurelan
Neurelan (TN)
P-Aminopyridine
PYRIDINE,4-AMINO
Philips 1861
Phillips 1861
Pimadin (free base)
Prc 1237
Pymadin
Pymadine
RCRA waste no. P008
SDCCGMLS-0066228.P001
SMR000058211
SPBio_001486
SPECTRUM1501130
STK298717
Spectrum2_001413
Spectrum3_000914
Spectrum4_001013
Spectrum5_001501
Spectrum_000155
Sustained Release, 4-Aminopyridine
TL8003344
Tocris-0940
UNII-BH3B64OKL9
UPCMLD-DP125
UPCMLD-DP125:001
VMI 10-3
VMI 103
VMI-10-3
VMI-103
VMI103
WLN: T6NJ DZ
[J.Pharmacol.Exp.Ther. 275:864 (1995)]
gamma-Aminopyridine
nchem.892-comp4
p-Aminopyridine
p-Aminopyridine [UN2671] [Poison]
p-Aminopyridine [UN2671] [Poison]
pyridin-4-amine
pyridin-4-ylamine
323,4-diaminopyridinePhase 2, Phase 319
33VaccinesPhase 3, Phase 2, Phase 16428
34Potassium Channel BlockersPhase 2, Phase 3176
35
Aluminum hydroxideapprovedPhase 220121645-51-2
Synonyms:
Al(OH)3
Aluminium hydroxide
Aluminium hydroxide gel, dried
 
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried
Dried aluminium hydroxide
Dried aluminum hydroxide gel
36ImmunoglobulinsPhase 2, Phase 16045
37AntibodiesPhase 2, Phase 16045
38Antibodies, MonoclonalPhase 13795
39Rho(D) Immune Globulin317
40gamma-Globulins317
41Immunoglobulins, Intravenous324

Interventional clinical trials:

(show all 19)
idNameStatusNCT IDPhase
1Botulism Outbreak in Thailand (Episode II)CompletedNCT00348426Phase 4
2Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.CompletedNCT00320281Phase 4
3BT-011 Pharmacokinetics of Botulism Antitoxin Heptavalent in Pediatric PatientsEnrolling by invitationNCT02051062Phase 4
4Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb JointTerminatedNCT01045694Phase 4
5Pilot Study on the Usefulness of 3,4-diaminopyridine in the Treatment of BotulismCompletedNCT01441557Phase 2, Phase 3
6Phase 3, Randomized, Safety, Lot Consistency and Clinical Benefit Study of Recombinant Botulinum Vaccine A/BSuspendedNCT01940315Phase 3
7Safety, Tolerability, and Immunogenicity Study of Investigational Recombinant Botulinum Vaccine A/B (rBV A/B) in Volunteers Previously Immunized With Investigational Pentavalent Botulinum ToxoidCompletedNCT01701999Phase 2
8Double Blind, Safety and Immunogenicity Study of Recombinant Botulinum Vaccine A/BCompletedNCT00764634Phase 2
9Botulism Antitoxin Effects on Paralysis Induced by Botulinum Neurotoxins in the EDB MuscleCompletedNCT00636519Phase 1
10Phase 1 PK Study of XOMA 3ABCompletedNCT01357213Phase 1
11Safety Study of 7 Botulinum Antitoxin Serotypes Derived From HorsesCompletedNCT00360737Phase 1
12Phase I, Dose Escalation Study to Evaluate the Safety and Pharmacokinetics of NTM-1632RecruitingNCT02779140Phase 1
13Evaluation of the Improvement of Quality of Life of Patients Suffering From Hailey Hailey or Darier Disease After Injections of Botulism Toxin Into Large Folds.Active, not recruitingNCT02782702Phase 1
14Study of Human Botulism Immunoglobulin in Infants With BotulismCompletedNCT00004401
15Treatment of Survivors After Botulism OutbreakCompletedNCT00314080
16Effect of Agave Syrup, Placebo, and No Treatment on Nocturnal Cough and Sleep Quality for Coughing Infants/Toddlers and Their ParentsCompletedNCT01721395
17Botulinum Toxin for the Treatment of Involuntary Movement DisordersRecruitingNCT00001208
18BT-010 Registry for the Evaluation of Safety and Clinical Outcomes in Patients Treated With Botulinum AntitoxinEnrolling by invitationNCT02055183
19Kinesiotaping Combined With Therapeutic Exercise in Upper Extremity Spasticity and Function in Subacute Stroke PatientsNot yet recruitingNCT03024190

Search NIH Clinical Center for Foodborne Botulism


Cochrane evidence based reviews: botulism

Genetic Tests for Foodborne Botulism

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Anatomical Context for Foodborne Botulism

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MalaCards organs/tissues related to Foodborne Botulism:

36
Spinal cord

Publications for Foodborne Botulism

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Articles related to Foodborne Botulism:

(show top 50)    (show all 59)
idTitleAuthorsYear
1
Foodborne botulism in Poland in 2014 (27779837)
2016
2
Outbreak of Foodborne Botulism Associated with Improperly Jarred Pesto - Ohio and California, 2014. (26914208)
2016
3
Early diagnosis and treatment in a child with foodborne botulism. (26688278)
2016
4
Regional variations in home canning practices and the risk of foodborne botulism in the republic of georgia, 2003. (25836400)
2015
5
Foodborne botulism in Poland in 2013. (26233080)
2015
6
Whole-Genome Sequence of Clostridium botulinum A2B3 87, a Highly Virulent Strain Involved in a Fatal Case of Foodborne Botulism in Italy. (25814616)
2015
7
Foodborne botulism associated with home-preserved turnip tops in Italy. (25857385)
2015
8
Outbreak of type E foodborne botulism linked to traditionally prepared salted fish in Ontario, Canada. (25188279)
2014
9
Foodborne botulism in Poland in 2012. (25135509)
2014
10
Outbreak of type A foodborne botulism at a boarding school, Uganda, 2008. (24576562)
2014
11
An outbreak of foodborne botulism in Surat Thani Province, Thailand, 2012. (23883854)
2013
12
Foodborne botulism in Poland in 2111. (24040723)
2013
13
Foodborne botulism treated with heptavalent botulism antitoxin. (23362041)
2013
14
National outbreak of type a foodborne botulism associated with a widely distributed commercially canned hot dog chili sauce. (23097586)
2013
15
Foodborne botulism in Canada, 1985-2005. (23735780)
2013
16
Diplopia as the primary presentation of foodborne botulism. (22993467)
2012
17
Treatment of foodborne botulism in current clinical toxicology. (22803000)
2012
18
Rapid detection of foodborne botulism outbreaks facilitated by epidemiological linking of cases: implications for food defense and public health response. (22315952)
2012
19
Treatment of foodborne botulism in current clinical toxicology: authors' reply. (25396032)
2012
20
Two unlinked cases of foodborne botulism in Italy at the beginning of 2010. (21811749)
2011
21
Epidemiology of foodborne botulism in Romania 1980-2009. (21495856)
2011
22
One collective case of type A foodborne botulism in Corsica. (21970773)
2011
23
Three outbreaks of foodborne botulism caused by unsafe home canning of vegetables--Ohio and Washington, 2008 and 2009. (22186049)
2011
24
Fatal course of foodborne botulism in an eight-month old infant. (22355516)
2011
25
Endemic foodborne botulism among Alaska Native persons--Alaska, 1947-2007. (21292663)
2011
26
Foodborne botulism in southwest Romania during the post-communism period 1990-2007. (19535277)
2010
27
Multilocus outbreak of foodborne botulism linked to contaminated sausage in Hebei province, China. (20569065)
2010
28
The role of a poison control center in identifying and limiting an outbreak of foodborne botulism. (20494246)
2010
29
An outbreak of foodborne botulism in Taiwan. (18396100)
2009
30
Signs and symptoms predictive of respiratory failure in patients with foodborne botulism in Thailand. (17690419)
2007
31
Foodborne botulism from home-prepared fermented tofu--California, 2006. (17287713)
2007
32
Outbreak of foodborne botulism linked to barbecue, Austria, 2006. (17213568)
2006
33
Two cases of foodborne botulism with home-preserved asparagus. (16557441)
2006
34
The safety of pasteurised in-pack chilled meat products with respect to the foodborne botulism hazard. (22063745)
2005
35
Foodborne botulism in the Republic of Georgia. (15498162)
2004
36
Signs and symptoms predictive of death in patients with foodborne botulism--Republic of Georgia, 1980-2002. (15307002)
2004
37
Foodborne botulism in the United States, 1990-2000. (15498163)
2004
38
Foodborne botulism in the Republic of Georgia: implications for preparedness planning. (15307003)
2004
39
An outbreak of foodborne botulism in Ontario. (18159458)
2003
40
An outbreak of foodborne botulism associated with food sold at a salvage store in Texas. (14614672)
2003
41
Foodborne botulism in a six-month-old infant caused by home-canned baby food. (12883510)
2003
42
Nine cases of foodborne botulism type B in France and literature review. (14605938)
2003
43
Two cases of foodborne botulism type E and review of epidemiology in France. (11347670)
2001
44
Foodborne botulism outbreaks following consumption of home-canned bamboo shoots in Northern Thailand. (11075968)
2000
45
From the Center for Disease Control and Prevention. Foodborne botulism from eating home-pickled eggs--Illinois, 1997. (11184244)
2000
46
Foodborne botulism from eating home-pickled eggs--Illinois, 1997. (10987245)
2000
47
Foodborne botulism associated with home-canned bamboo shoots--Thailand, 1998. (10372500)
1999
48
Surveillance of foodborne botulism in Poland: 1960-1998. (12631899)
1999
49
Foodborne botulism in Italy. (8950913)
1996
50
From the Centers for Disease Control and Prevention. Foodborne botulism--Oklahoma, 1994. (7707612)
1995

Variations for Foodborne Botulism

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Expression for genes affiliated with Foodborne Botulism

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Search GEO for disease gene expression data for Foodborne Botulism.

Pathways for genes affiliated with Foodborne Botulism

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GO Terms for genes affiliated with Foodborne Botulism

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Cellular components related to Foodborne Botulism according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chromaffin granule membraneGO:004258410.4SYT1, SYT2
2presynaptic membraneGO:004273410.3SNAP25, SYT1
3SNARE complexGO:003120110.3SNAP25, SYT1
4synaptic vesicle membraneGO:00306729.8SYT1, SYT2

Biological processes related to Foodborne Botulism according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1glutamate secretionGO:001404710.4SNAP25, SYT1
2calcium ion-regulated exocytosis of neurotransmitterGO:004879110.4SYT1, SYT2
3neurotransmitter secretionGO:000726910.4SNAP25, SYT1
4positive regulation of dendrite extensionGO:190386110.3SYT1, SYT2
5regulation of calcium ion-dependent exocytosisGO:001715810.3SYT1, SYT2
6synaptic vesicle endocytosisGO:004848810.3SYT1, SYT2
7synaptic vesicle exocytosisGO:001607910.3SNAP25, SYT1
8vesicle fusionGO:00069069.8SYT1, SYT2

Molecular functions related to Foodborne Botulism according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1calcium-dependent phospholipid bindingGO:000554410.4SYT1, SYT2
2calcium-dependent protein bindingGO:004830610.4SNAP25, SYT1
3clathrin bindingGO:003027610.3SYT1, SYT2
4syntaxin bindingGO:001990510.1SYT1, SYT2
5syntaxin-1 bindingGO:00170759.8SNAP25, SYT1

Sources for Foodborne Botulism

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet