Aliases & Classifications for Foot Drop

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Aliases & Descriptions for Foot Drop:

Name: Foot Drop 48

Summaries for Foot Drop

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NINDS:48 Foot drop describes the inability to raise the front part of the foot due to weakness or paralysis of the muscles that lift the foot. As a result, individuals with foot drop scuff their toes along the ground or bend their knees to lift their foot higher than usual to avoid the scuffing, which causes what is called a ?steppage? gait. Foot drop can be unilateral (affecting one foot) or bilateral (affecting both feet). Foot drop is a symptom of an underlying problem and is either temporary or permanent, depending on the cause. Causes include: neurodegenerative disorders of the brain that cause muscular problems, such as multiple sclerosis, stroke, and cerebral palsy; motor neuron disorders such as polio, some forms of spinal muscular atrophy and amyotrophic lateral sclerosis (commonly known as Lou Gehrig?s disease); injury to the nerve roots, such as in spinal stenosis; peripheral nerve disorders such as Charcot-Marie-Tooth disease or acquired peripheral neuropathy; local compression or damage to the peroneal nerve as it passes across the fibular bone below the knee; and muscle disorders, such as muscular dystrophy or myositis.

MalaCards based summary: Foot Drop is related to charcot-marie-tooth disease, type 1e and diffuse large b-cell lymphoma. An important gene associated with Foot Drop is ACTA1 (Actin, Alpha 1, Skeletal Muscle), and among its related pathways are Striated Muscle Contraction and Neural Crest Differentiation. Affiliated tissues include brain, bone and spinal cord, and related mouse phenotypes are behavior/neurological and muscle.

Wikipedia:70 Foot drop is a gait abnormality in which the dropping of the forefoot happens due to weakness,... more...

Related Diseases for Foot Drop

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Diseases related to Foot Drop via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 105)
idRelated DiseaseScoreTop Affiliating Genes
1charcot-marie-tooth disease, type 1e31.1MPZ, PMP22
2diffuse large b-cell lymphoma28.9MPZ, PMP22
3scapuloperoneal myopathy, x-linked dominant10.9
4myopathy, scapulohumeroperoneal10.9
5leprosy10.2
6megalocytic interstitial nephritis10.1ACTA1, NEB
7dandy-walker malformation associated with macrocephaly, facial anomalies, developmental delay, and brain stem dysgenesis10.1ACTA1, NEB
8undifferentiated connective tissue disease10.1ACTA1, NEB
9neuropathy10.1
10x-linked intellectual disability - short stature - obesity10.1ACTA1, NEB
11endometrial stromal sarcoma10.1ACTA1, NEB
12myopathy, lactic acidosis, and sideroblastic anemia10.0FHL1, NEB
13cerebritis10.0
14spasticity10.0
15cylindrical spirals myopathy10.0ACTA1, NEB
16lymphoma9.9
17neuromuscular disease9.9
18hereditary orotic aciduria without megaloblastic anaemia9.9MPZ, PMP22
19congestive heart failure9.9MPZ, PMP22
20secondary hypertrophic osteoarthropathy9.9MPZ, PMP22
21charcot-marie-tooth neuropathy type 2e/1f9.9MPZ, PMP22
22anal canal adenocarcinoma9.9MPZ, PMP22
23hypertonia9.9MPZ, PMP22
24potocki-lupski syndrome9.9MPZ, PMP22
25trachea leiomyoma9.9MPZ, PMP22
26charcot-marie-tooth disease9.8
27tooth disease9.8
28syringomyelia9.8
29peroneal neuropathy9.8
30radiculopathy9.8
31herpes zoster9.8
32vasculitis9.8
33cellular schwannoma9.8ACTA1, NEB
34chronic polyneuropathy9.8MPZ, PMP22
35smooth muscle tumor9.8MPZ, PMP22
36angiodysplasia9.8MPZ, PMP22
37mohr-tranebjaerg syndrome9.8MPZ, PMP22
38thrombophilia due to antithrombin iii deficiency9.8MPZ, PMP22
39pancreatic vasoactive intestinal peptide producing tumor9.8MPZ, PMP22
40achilles bursitis9.8MPZ, PMP22
41secondary lacrimal atrophy9.8MPZ, PMP22
42prostate cancer9.8
43anorexia nervosa9.8
44cerebral palsy9.8
45polyneuropathy9.8
46prostatitis9.8
47endometriosis9.8
48purpura9.8
49compartment syndrome9.8
50muscular dystrophy9.8

Graphical network of the top 20 diseases related to Foot Drop:



Diseases related to foot drop

Symptoms for Foot Drop

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Drugs & Therapeutics for Foot Drop

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Drugs for Foot Drop (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 95)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Hyaluronic acidapproved, vet_approvedPhase 44399004-61-953477741, 24759
Synonyms:
Hyaluronan
Hyaluronate
Hyaluronic acid
Hylartil
Hyruan Plus
Luronit
 
Macronan
Mucoitin
Nutra-HAF
Q 5AQ
Sepracoat
Sepragel Sinus
Sofast
Synvisc
2
AcetylcholineapprovedPhase 477651-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
3
Bimatoprostapproved, investigationalPhase 4132155206-00-15311027
Synonyms:
(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1e,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
155206-00-1
15M
267244-98-4
5-Heptenamide,7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ehtyl-,(5Z)
AC1NSJUW
AGN 192024
AGN-192024
Bimataprost [USAN:INN:BAN]
Bimatoprost
Bimatoprost (JAN/USAN/INN)
Bimatoprost [USAN:INN:BAN]
Bimatoprostum
 
CHEBI:39562
CHEBI:51230
CHEMBL1200963
CID5311027
D02724
DB00905
DB06863
I06-1275
I06-1277
LS-181817
Latisse
Lumigan
Lumigan (TN)
NCGC00181745-01
UNII-QXS94885MZ
ZINC04474405
bimatoprostum
4
RibavirinapprovedPhase 498436791-04-537542
Synonyms:
1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide
36791-04-5
437710-49-1
66510-90-5
AA-504/07617051
AB00430481
AC1L1XXZ
AC1Q1IDC
AC1Q4ZGS
AKOS001715163
BB_NC-0567
BPBio1_001195
BRN 0892462
BSPBio_001085
BSPBio_003352
C-Virin
CHEMBL1643
CID37542
Copegus
Copegus (TN)
Cotronak
D00423
DB00811
DRG-0028
DivK1c_000782
Drug: Ribavirin
EU-0101063
FT-0082885
HMS2090L15
HMS2094O09
HMS502H04
HSDB 6513
ICN-1229
IDI1_000782
KBio1_000782
KBio2_002328
KBio2_004896
KBio2_007464
KBio3_002854
KBioGR_001804
KBioSS_002331
KS-1104
LS-1241
Lopac0_001063
MLS000028486
MLS002222317
MolPort-002-507-104
MolPort-002-885-856
NCGC00090726-01
NCGC00090726-03
NCGC00090726-04
NCGC00090726-05
NCGC00090726-06
NCGC00090726-07
NINDS_000782
NSC 163039
 
NSC163039
Prestwick3_000993
R 9644
R-964
R9644_SIGMA
RBV
RG-964
RIBAV
RTC
RTCA
RTP
Ravanex
Rebetol
Rebetol (TN)
Rebetron
Rebretron
Ribacine
Ribamide
Ribamidil
Ribamidyl
Ribasphere
Ribasphere (TN)
Ribav
Ribavirin
Ribavirin (JAN/USP/INN)
Ribavirin Capsules
Ribavirin Triphosphate
Ribavirin [USAN:INN]
Ribavirin-TP
Ribavirina
Ribavirina [INN-Spanish]
Ribavirine
Ribavirine [INN-French]
Ribavirinum
Ribavirinum [INN-Latin]
Ribovirin
Ro 20-9963/000
Ro-20-9963
S2504_Selleck
SCH 18908
SMP1_000261
SMR000058315
SPECTRUM1503938
SR-01000076112-3
Spectrum3_001876
Spectrum4_001252
Spectrum5_002075
Spectrum_001826
Tribavirin
UNII-49717AWG6K
Varazid
Vilona
Viramid
Viramide
Virazid
Virazide
Virazole
Virazole (Ribavirin) Inhalation Solution
Virazole (TN)
Virazole 5'-triphosphate
ZINC01035331
ribavirin
5
Mannitolapproved, investigationalPhase 426869-65-8453, 6251
Synonyms:
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
(L)-Mannitol
1,2,3,4,5,6-Hexanehexol
123897-58-5
133-43-7
15719_ALDRICH
15719_RIEDEL
33440_RIEDEL
33440_SIGMA
36413-61-3
4-01-00-02841 (Beilstein Handbook Reference)
5149-40-6
63559_FLUKA
63559_SIGMA
63560_FLUKA
63565_FLUKA
63565_SIGMA
69-65-8
75398-80-0
85085-15-0
87-78-5
AB1002081
AC-12776
AC1L1M49
AC1Q28E5
AI3-19511
AR-1J3861
Ambap69-65-8
BRN 1721898
C00392
C6H14O6
CCRIS 369
CHEBI:16899
CHEMBL689
CID6251
Cordycepate
Cordycepic acid
D-(-)-Mannitol
D-Mannitol
D-Mannitol (JP15)
D-mannite
D-mannitol
D00062
D008353
DL-Mannitol
Diosmol
ED1D1E61-FEFB-430A-AFDC-D1F4A957FC3D
EINECS 200-711-8
EINECS 201-770-2
Fraxinine
HSDB 714
Hexahydroxyhexane
Hexanhexol
Invenex
Isotol
LS-1588
LS-89250
M0044
M1902_SIGMA
M4125_SIAL
M8429_SIAL
M9546_SIAL
M9647_SIAL
MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER
MANNITOL 15% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.45%
 
MANNITOL 25%
MANNITOL 5% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.12%
MLS001335977
MLS001335978
MTL
Manicol
Manitol
Maniton S
Maniton-S
Manna Sugar
Manna sugar
Mannazucker
Mannidex
Mannidex 16700
Mannigen
Mannistol
Mannit
Mannit p
Mannite
Mannitol
Mannitol (USP)
Mannitol (VAN)
Mannitol 10%
Mannitol 10% In Plastic Container
Mannitol 15%
Mannitol 15% In Plastic Container
Mannitol 20%
Mannitol 20% In Plastic Container
Mannitol 5%
Mannitol 5% In Plastic Container
Mannitol [USAN]
Mannitolum
Mannogem 2080
Marine Crystal
Marine crystal
MolPort-003-927-039
Mushroom sugar
NCGC00164246-01
NCI-C50362
NSC 407017
NSC 9256
OSMITROL 10% IN WATER IN PLASTIC CONTAINER
OSMITROL 15% IN WATER IN PLASTIC CONTAINER
OSMITROL 20% IN WATER IN PLASTIC CONTAINER
OSMITROL 5% IN WATER IN PLASTIC CONTAINER
Osmitrol
Osmitrol (TN)
Osmitrol 10% In Water
Osmitrol 15% In Water
Osmitrol 20% In Water
Osmitrol 5% In Water
Osmofundin
Osmosal
Resectisol
Resectisol In Plastic Container
SDM No. 35
SMR000857324
SORBITOL-MANNITOL IN PLASTIC CONTAINER
Sorbitol-Mannitol
TL806434
UNII-3OWL53L36A
ZINC02041302
bmse000099
cpd without stereochemical designation
e 421
e-421
e421
manita
mannitol
6
Folic Acidapproved, nutraceutical, vet_approvedPhase 4, Phase 3, Phase 2427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
7
Thiamineapproved, nutraceutical, vet_approvedPhase 49859-43-81130
Synonyms:
100660-17-1
115461-66-0
1sbr
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydrox yethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethylthiazolium chloride, monohydrochloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride monohydrochloride
3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
3-(4-AMINO-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium
3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride
3[(4-Amino-2-methyl-5-pyrimidinyl)-methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
55463-15-5
57777-32-9
59-43-8
67-03-8
AC-11683
AC1L1ASK
AC1L1LOC
AC1LAODT
AC1Q4V9Q
AI3-18993
AKOS000668650
AR-1L8201
Aneurin
Aneurine
Antiberiberi factor
Apatate drape
Apate drops
B-Amin
BAS 00266240
BPBio1_000686
BSPBio_000622
Beatine
Bedome
Begiolan
Beivon
Benerva
Bequin
Berin
Betabion
Betalin S
Betaxin
Bethiamin
Bethiazine
Beuion
Bevitex
Bevitine
Bewon
Biamine
Bithiamin
Biuno
Bivatin
Bivita
C00378
C12H17N4OS
CCRIS 1906
CCRIS 5823
CHEBI:18385
CHEBI:33283
CHEBI:49105
CHEMBL1547
CHEMBL1588
CID1130
CID517305
CID6042
Cernevit-12
Chloride-hydrochloride salt of thiamine
Clotiamina
D08580
DB00152
EINECS 200-425-3
EINECS 200-641-8
Eskapen
Eskaphen
FEMA No. 3322
 
HSDB 220
Hybee
I14-14339
LS-3226
LT00233141
Lixa-beta
MLS001304099
Metabolin
MolPort-000-722-048
MolPort-001-920-086
MolPort-002-052-059
NChemBio.2007.13-comp10
NSC 36226
NSC36226
Oryzanin
Oryzanine
Prestwick0_000631
Prestwick1_000631
Prestwick2_000631
Prestwick3_000631
SBB058094
SMP1_000084
SMR000718788
SPBio_002841
ST095175
Slowten
THD
THIAMIN, VITAMIN B1
Thiadoxine
Thiamin
Thiamin dichloride
Thiaminal
Thiamine
Thiamine (INN)
Thiamine HCL
Thiamine [INN:BAN]
Thiamine chloride
Thiamine chloride hydrochloride
Thiamine dichloride
Thiamine hydrochloride [JAN]
Thiamine monochloride
Thiamine monohydrochloride
Thiamine, chloride
Thiamine, chloride, hydrochloride
Thiamine, monohydrochloride
Thiaminium
Thiaminium chloride hydrochloride
Thiaminum
Thiaminum [INN-Latin]
Thiamol
Thiavit
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethyl, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride (1:1)
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-chloride
Tiamidon
Tiamina
Tiamina [INN-Spanish]
Tiaminal
TimTec1_000613
Trophite
UNII-X66NSO3N35
VIB
Vetalin S
Vinothiam
Vitamin B1
Vitamin B1 (TN)
Vitamin B1 hydrochloride (VAN)
Vitaneurin
Vitaneuron
ZINC00049153
[5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methylpyrimidin-4-yl]azanium dichloride
bmse000274
nchembio.121-comp5
thiamin
thiamine
thiamine(1+)
thiamine(1+) ion
thiaminium
vitamin B1
vitamin b1(thiamine)
8Neurotransmitter AgentsPhase 4, Phase 2, Phase 317734
9Vitamin B ComplexPhase 4, Phase 3, Phase 24229
10VitaminsPhase 4, Phase 25095
11Pharmaceutical SolutionsPhase 47793
12Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 322776
13Antihypertensive AgentsPhase 4, Phase 2, Phase 34095
14AntimetabolitesPhase 4, Phase 311774
15ViscosupplementsPhase 4364
16abobotulinumtoxinAPhase 4626
17onabotulinumtoxinAPhase 4626
18Botulinum Toxins, Type APhase 4630
19Botulinum ToxinsPhase 4669
20Adjuvants, ImmunologicPhase 42484
21Protective AgentsPhase 4, Phase 27190
22Cholinergic AgentsPhase 43846
23Ophthalmic SolutionsPhase 41092
24Neuromuscular AgentsPhase 41129
25incobotulinumtoxinAPhase 4635
26Trace ElementsPhase 4, Phase 25802
27MicronutrientsPhase 4, Phase 25802
28Antiviral AgentsPhase 49732
29Anti-Infective AgentsPhase 421402
30FolateNutraceuticalPhase 4, Phase 3, Phase 24279
31Vitamin B9NutraceuticalPhase 4, Phase 3, Phase 24279
32ThiaminNutraceuticalPhase 498
33
OndansetronapprovedPhase 2, Phase 330999614-02-54595
Synonyms:
(RS)-1,2,3,9-Tetrahydro-9-methyl-3-(2-methylimidazol-1-ylmethyl)carbazol-4-one
1,2,3,9-Tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one
103639-04-9 (mono-hydrochloride dihydrate)
108303-49-7
116002-70-1
9-Methyl-3-(2-methyl-imidazol-1-ylmethyl)-1,2,3,9-tetrahydro-carbazol-4-one
9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one
9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one
99614-01-4 (mono-hydrochloride)
99614-02-5
AB00373674
AC1L1IIM
AKOS000599484
Apo-ondansetron
BAS 00717177
BPBio1_001118
BRD-A19736161-001-01-8
BRD-A19736161-003-03-0
BRN 3622981
BSPBio_001016
C07325
C18H19N3O
CBDivE_008994
CHEMBL46
CID4595
CPD001307702
D00456
DB00904
DESMETHYLONDANSETRON
GR 38032
GR 38032X
GR-38032F
GR38032F
HMS2090H16
I06-0687
I06-1329
 
L000456
LS-172305
LS-51878
MolPort-001-944-253
NCI60_022780
Novo-ondansetron
Ondansetron
Ondansetron (JAN/USP/INN)
Ondansetron [USAN:INN:BAN]
Ondansetron, (+,-)-Isomer
Oprea1_435466
Oprea1_852372
PHL-ondansetron
PMS-ondansetron
Prestwick0_001058
Prestwick1_001058
Prestwick2_001058
Prestwick3_001058
Ratio-ondansetron
SAM002589958
SN-307
SPBio_002938
STK370548
STOCK4S-10990
Sandoz ondansetron
TL8006071
TimTec1_001750
UNII-4AF302ESOS
ZOFRAN IN PLASTIC CONTAINER
Zofran
Zofran ODT
Zofran ODT (TN)
Zofran odt
Zophren
Zudan
ondansetron
ondansetron (Zofran)
34
Tofacitinibapproved, investigationalPhase 3104477600-75-2
Synonyms:
 
Tasocitinib
Tofacitinibum
35
MethotrexateapprovedPhase 315181959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
36Psychotropic DrugsPhase 2, Phase 36279
37
SerotoninPhase 2, Phase 3356650-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
38Tranquilizing AgentsPhase 2, Phase 34164
39Serotonin AntagonistsPhase 2, Phase 31381
40Serotonin AgentsPhase 2, Phase 33102
41Dermatologic AgentsPhase 2, Phase 35674
42Gastrointestinal AgentsPhase 2, Phase 38109
43Anti-Anxiety AgentsPhase 2, Phase 31816
44AnestheticsPhase 2, Phase 3, Early Phase 19001
45AntipruriticsPhase 2, Phase 3864
46AntiemeticsPhase 2, Phase 33888
47Antipsychotic AgentsPhase 2, Phase 32359
48Central Nervous System DepressantsPhase 2, Phase 312806
49Autonomic AgentsPhase 2, Phase 39774
50Immunosuppressive AgentsPhase 3, Phase 212770

Interventional clinical trials:

(show top 50)    (show all 53)
idNameStatusNCT IDPhase
1Patient Satisfaction Study of Combined Facial Treatment With BOTOX® Cosmetic, JUVÉDERM® and LATISSE® (HARMONY Study)CompletedNCT02176356Phase 4
2Effect of Xiaoer Jiebiao Oral Liquid on Hand-foot-mouth DiseaseRecruitingNCT02328651Phase 4
3Thiamin Deficiency in Obese Thai ChildrenRecruitingNCT02464865Phase 4
4Effects of Functional Electrical Stimulation on Gait in Children With Cerebral PalsyNot yet recruitingNCT02462018Phase 4
5Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy ParturientsUnknown statusNCT01414777Phase 2, Phase 3
6Evaluation of the Safety and Performance of the NESS L300 Plus SystemCompletedNCT01237860Phase 3
7Comparing The Effectiveness And Safety Of 2 Doses Of An Experimental Drug, CP-690,550, To Methotrexate (MTX) In Patients With Rheumatoid Arthritis Who Have Not Previously Received MTXCompletedNCT01039688Phase 3
8Multi-pad FES System for Drop Foot TreatmentRecruitingNCT02729636Phase 2, Phase 3
9Functional Electrical Stimulation for Footdrop in HemiparesisCompletedNCT00148343Phase 2
10Effect of Robot-assisted Training on Foot Drop in Multiple SclerosisCompletedNCT00872053Phase 1, Phase 2
11Extracorporeal Shockwave Treatment for Chronic Soft Tissue WoundsCompletedNCT00545896Phase 2
12The Role of Cytokines on Growth Hormone Suppression in Premenopausal Women With Rheumatoid Arthritis and the Effect of Treatment With EtanerceptCompletedNCT00034060Phase 2
13A Phase I/II Double-blind Safety and Efficacy Evaluation of Nowarta110 in Patients With Plantar WartsCompletedNCT02338336Phase 1, Phase 2
14Ankle Robot to Reduce Foot-drop in StrokeRecruitingNCT02483676Phase 2
15Essential Oils for Enhancing QOL in ASDRecruitingNCT02543203Phase 2
16Marched Pair Study Conventional Doxorubicin(DOX) Versus Pegylated Liposomal Doxorubicin(PLD) Neoadjuvant ChemotherapyRecruitingNCT02953184Phase 2
17Targeted Lower Extremity Joint TrainingTerminatedNCT00765544Phase 1, Phase 2
18Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in StrokeUnknown statusNCT02199795Phase 1
19Pilot Study Assessing the Feasibility of Treating Foot Drop With the Neurostep™ System.CompletedNCT00860210Phase 1
20Electrical Stimulation for Recovery of Ankle Dorsiflexion in Chronic Stroke SurvivorsCompletedNCT01029912Phase 1
21Effect of FES Interventions on Gait Dynamics in Stroke PopulationUnknown statusNCT01952613
22A Clinical Trial to Evaluate the Effectiveness and Safety of Xiyanping Injection in the Treatment of Mild Type of Hand, Foot, and Mouth DiseaseUnknown statusNCT01182025
23Eccentric Exercise for Chronic Mid-portion Achilles TendinopathyUnknown statusNCT01225497
24Treating Foot Drop in People With Multiple Sclerosis Using Electrical StimulationCompletedNCT02123537
25Walking With FES or AFO in People With MS With Foot DropCompletedNCT01977287
26Evaluation of Dual Channel vs. Single Channel FES for DropfootCompletedNCT02494323
27Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot DropCompletedNCT01138995
28Functional Electrical Stimulation for People With Multiple Sclerosis Who Experience Foot DropCompletedNCT01914016
29Clinical Study to Evaluate the Implantation of the ActiGait Drop Foot Stimulator SystemCompletedNCT01116466
30Effects of Targeted Lower Extremity Joint Training on Multiple Sclerosis (MS) Gait AbnormalitiesCompletedNCT00906737
31WalkAide Compared to Ankle-Foot Orthosis (AFO) in Stroke PatientsCompletedNCT01087957
32Tibial Nerve Versus Sciatic Nerve BlockCompletedNCT01415193
33Efficacy of the WalkAide and AFOs for CVACompletedNCT00216320
34Comparison Between Implanted Functional Electrical Stimulation and Foot OrthosisCompletedNCT01415700
35Approach to Continuous Sciatic Nerve Block for Orthopedic Procedures in Day Surgery With Two Different TechniquesCompletedNCT02029404
36Study of Changes in the Feet With PregnancyCompletedNCT01868074
37Effects of Weight Loss on Foot Structure and Function in Obese Adults: A Pilot StudyCompletedNCT01782144
38Treatment of Painful Diabetic Neuropathy With Photon StimulationCompletedNCT00539175
39PAHA Study: Psychological Active and Healthy AgeingCompletedNCT01966562
40Comparison of Different Treatment Methods for Gait Rehabilitation of Sub-Acute Post Stroke Patients With Dropped FootRecruitingNCT01876030
41Extramembranous and Interosseous Technique of Tibialis Posterior Tendon TransferRecruitingNCT01751503
42Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.RecruitingNCT02693834
43Acute Nerve Decompression Versus Non-operative Treatment for Peroneal Nerve Palsy Following Primary Total Knee ArthroplastyRecruitingNCT02856958
44Clinical Effects of Peroneal Nerve Functional Electrical Stimulation (WalkAide[R]) for Chronic Stroke PatientsRecruitingNCT02897752
45Interactive Exoskeleton Robot for Walking - Ankle JointRecruitingNCT02471248
46Pathological Basis of MRI Signal Changes in Multiple SclerosisRecruitingNCT02659956
47A Surveillance Study of Diseases Specified as Adverse Events of Specific Interest (AESI) and Serious Adverse Events (SAEs) in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate VaccineRecruitingNCT02374450
48Chromosome 18 Clinical Research CenterRecruitingNCT00227253
49Evaluation of Usability and Human Factors in the Novus SystemNot yet recruitingNCT02738242
50Pairing Functional Electrical Stimulation (FES) and Volitional Effort Training Promotes Neuroplasticity and Motor GainNot yet recruitingNCT02797886

Search NIH Clinical Center for Foot Drop

Genetic Tests for Foot Drop

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Anatomical Context for Foot Drop

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MalaCards organs/tissues related to Foot Drop:

35
Brain, Bone, Spinal cord, Prostate, B cells, Myeloid, Skin

Animal Models for Foot Drop or affiliated genes

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MGI Mouse Phenotypes related to Foot Drop:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.3ACTA1, FHL1, MPZ, NEB, PMP22
2MP:00053698.1ACTA1, FHL1, NEB, PMP22

Publications for Foot Drop

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Articles related to Foot Drop:

(show top 50)    (show all 307)
idTitleAuthorsYear
1
Functional electrical stimulation versus ankle foot orthoses for foot-drop: A meta-analysis of orthotic effects. (27563700)
2016
2
Foot drop following closed reduction of a total hip replacement. (27005799)
2016
3
WITHDRAWN: Rehabilitation interventions for foot drop in neuromuscular disease. (25927103)
2015
4
Changes in center of pressure displacement with the use of a foot drop stimulator in individuals with stroke. (26003198)
2015
5
Bilateral foot-drop as predominant symptom in nebulin (NEB) gene related "core-rod" congenital myopathy. (26403434)
2015
6
Misunderstanding of foot drop in a patient with charcot-marie-tooth disease and lumbar disk herniation. (25932299)
2015
7
Comparative analysis and quantitative evaluation of ankle-foot orthoses for foot drop in chronic hemiparetic patients. (25184801)
2014
8
Reply to Comments on 'Gait Disturbance due to Foot Drop Is Refractory to Treatment in Nonsystemic Vasculitic Neuropathy' (25401459)
2014
9
Experiences of functional electrical stimulation (FES) and ankle foot orthoses (AFOs) for foot-drop in people with multiple sclerosis. (24796365)
2014
10
Poststroke muscle architectural parameters of the tibialis anterior and the potential implications for rehabilitation of foot drop. (25133011)
2014
11
Clinical reasoning: a 55-year-old man with weight loss, ataxia, and foot drop. (24960835)
2014
12
Foot drop after a suicide attempt. (24878838)
2014
13
EMG of the tibialis anterior demonstrates a training effect after utilization of a foot drop stimulator. (24990033)
2014
14
Foot drop in an adolescent with muscle edema in the anterior compartment. (23402740)
2013
15
Gait phase detection from sciatic nerve recordings in functional electrical stimulation systems for foot drop correction. (23604025)
2013
16
Foot drop caused by lumbar degenerative disease: clinical features, prognostic factors of surgical outcome and clinical stage. (24224052)
2013
17
Spastic foot-drop as an isolated manifestation of neurocysticercosis. (23008377)
2012
18
Solitary lumbar osteochondroma presenting with foot-drop: a case report. (22665015)
2012
19
New devices compensate for foot drop. Nerve stimulation can help many people walk normally again. (23437467)
2012
20
Maternal sacral fracture during delivery causing foot drop. (21978815)
2011
21
Clinical features of central isolated unilateral foot drop: A case report and review of the literature. (21541007)
2011
22
A bilateral foot drop due to neuroschistosomiasis. (20127348)
2010
23
Early postoperative active mobilisation versus immobilisation following tibialis posterior tendon transfer for foot-drop correction in patients with Hansen's disease. (19230819)
2010
24
Interosseous nerve transfers for tibialis anterior muscle paralysis (foot drop): a human cadaver-based feasibility study. (19048462)
2009
25
Giant popliteal aneurysm with deep vein thrombosis, foot drop and arteriomegali. (21686392)
2009
26
Foot-drop: an unusual complaint in Henoch-SchAPnlein purpura. (18773224)
2009
27
Infantile onset neurofibromatosis type 2 presenting with peripheral facial palsy, skin patches, retinal hamartoma and foot drop. (19629903)
2009
28
Neuropathic pain and foot drop related to nerve injury after short duration surgery and caudal analgesia. (18716505)
2008
29
Delayed diagnosis of brain tumor in a patient with flexor spasms and spastic foot drop. (19893685)
2008
30
Rehabilitation interventions for foot drop in neuromuscular disease. (17443532)
2007
31
Foot drop as a complication of weight loss after bariatric surgery: is it preventable? (18074496)
2007
32
Central causes of foot drop: rare and underappreciated differential diagnoses. (17385271)
2007
33
Ganglion cyst of the proximal tibiofibular joint causing foot drop-diagnostic problem of differentiating from neuritic leprosy. (16044814)
2005
34
Clinical approach to a patient presenting with foot drop. (19078736)
2004
35
Botulinum toxin A in the treatment of hemiplegic spastic foot drop--clinical and functional outcomes. (11063169)
2000
36
Bilateral foot drop as a manifestation of myasthenia gravis. (19078598)
2000
37
Postoperative gas bubble foot drop. A case report. (10025027)
1999
38
Unilateral foot drop. (8949602)
1996
39
Foot drop as a harbinger of aortic occlusion. (7630352)
1995
40
Reply: 'Results of surgical procedures for the correction of foot-drop and lagophthalmus due to leprosy'. (7861931)
1994
41
Bilateral foot drop, weight loss and rectal bleeding as an acute presentation of Crohn's disease. (7831180)
1994
42
Weight loss and foot drop. (8392041)
1993
43
Results of surgical procedures for the correction of foot-drop and of lagophthalmus due to leprosy. (1406020)
1992
44
Fever and foot drop in a 61-year-old man. (1969505)
1990
45
Observations of tarsal disintegration in the cases operated for foot-drop. (3831098)
1985
46
Strawberry pickers' foot drop. (912290)
1977
47
Biofeedback treatment of foot drop after stroke compared with standard rehabilitation technique (part 2): effects on nerve conduction velocity and spasticity. (1247378)
1976
48
FOOT DROP IN LEPROSY. (14114051)
1964
49
Acute bilateral foot-drop in children. (14413748)
1959
50
Foot drop strap. (13238524)
1955

Variations for Foot Drop

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Expression for genes affiliated with Foot Drop

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Search GEO for disease gene expression data for Foot Drop.

Pathways for genes affiliated with Foot Drop

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Pathways related to Foot Drop according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.4ACTA1, NEB
29.1MPZ, PMP22

GO Terms for genes affiliated with Foot Drop

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Biological processes related to Foot Drop according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle organ developmentGO:00075179.3FHL1, NEB
2muscle filament slidingGO:00300499.1ACTA1, NEB

Sources for Foot Drop

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet