Aliases & Classifications for Foot Drop

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Aliases & Descriptions for Foot Drop:

Name: Foot Drop 49

Summaries for Foot Drop

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NINDS:49 Foot drop describes the inability to raise the front part of the foot due to weakness or paralysis of the muscles that lift the foot. As a result, individuals with foot drop scuff their toes along the ground or bend their knees to lift their foot higher than usual to avoid the scuffing, which causes what is called a “steppage” gait. Foot drop can be unilateral (affecting one foot) or bilateral (affecting both feet). Foot drop is a symptom of an underlying problem and is either temporary or permanent, depending on the cause. Causes include: neurodegenerative disorders of the brain that cause muscular problems, such as multiple sclerosis, stroke, and cerebral palsy; motor neuron disorders such as polio, some forms of spinal muscular atrophy and amyotrophic lateral sclerosis (commonly known as Lou Gehrig’s disease); injury to the nerve roots, such as in spinal stenosis; peripheral nerve disorders such as Charcot-Marie-Tooth disease or acquired peripheral neuropathy; local compression or damage to the peroneal nerve as it passes across the fibular bone below the knee; and muscle disorders, such as muscular dystrophy or myositis.

MalaCards based summary: Foot Drop is related to charcot-marie-tooth disease, type 1e and congenital myopathy. An important gene associated with Foot Drop is MPZ (Myelin Protein Zero), and among its related pathways are Neural Crest Differentiation and Striated Muscle Contraction. Affiliated tissues include brain, bone and spinal cord, and related mouse phenotypes are behavior/neurological and muscle.

Wikipedia:71 Foot drop is a gait abnormality in which the dropping of the forefoot happens due to weakness,... more...

Related Diseases for Foot Drop

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Diseases related to Foot Drop via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 116)
idRelated DiseaseScoreTop Affiliating Genes
1charcot-marie-tooth disease, type 1e31.4MPZ, PMP22
2congenital myopathy29.6FHL1, NEB
3myopathy29.4ACTA1, NEB
4charcot-marie-tooth disease11.3
5scapuloperoneal myopathy, x-linked dominant10.8
6cauda equina syndrome10.8
7myopathy, scapulohumeroperoneal10.8
8leprosy10.2
9neuropathy10.1
10hereditary type 2 neuropathy10.1MPZ, PMP22
11craniorachischisis10.1MPZ, PMP22
12chrna1-related congenital myasthenic syndrome10.1MPZ, PMP22
13surfactant metabolism dysfunction, pulmonary, 210.1MPZ, PMP22
14pneumonic plague10.1MPZ, PMP22
15deafness, autosomal recessive 7610.1MPZ, PMP22
16classic galactosemia and clinical variant galactosemia10.1MPZ, PMP22
17hypertrophic osteoarthropathy, primary, autosomal recessive 210.1MPZ, PMP22
18neuropathy, inflammatory demyelinating10.1MPZ, PMP22
19acute sanguinous otitis media10.1MPZ, PMP22
20dejerine-sottas disease10.1MPZ, PMP22
21nephrolithiasis, uric acid10.1MPZ, PMP22
22chkb-related muscle diseases10.1MPZ, PMP22
23infantile epileptic encephalopathy10.1MPZ, PMP22
24potocki-lupski syndrome10.1MPZ, PMP22
25von economo's disease10.1MPZ, PMP22
26pituitary adenoma, prolactin-secreting10.1MPZ, PMP22
27mohr-tranebjaerg syndrome10.1MPZ, PMP22
28non-gestational choriocarcinoma10.1MPZ, PMP22
29korsakoff's amnesic syndrome10.1MPZ, PMP22
30neuropathy, congenital hypomyelinating10.1MPZ, PMP22
31choreatic disease10.0MPZ, PMP22
32status epilepticus10.0MPZ, PMP22
33senile angioma10.0MPZ, PMP22
34thrombophilia due to antithrombin iii deficiency10.0MPZ, PMP22
35uterine ligament serous adenocarcinoma10.0MPZ, PMP22
36iodine antenatal infection10.0ACTA1, NEB
37short limbs abnormal face congenital heart disease10.0ACTA1, NEB
38chondrodysplasia calcificans metaphysealis10.0ACTA1, NEB
39undifferentiated pleomorphic sarcoma10.0ACTA1, NEB
40dilated cardiomyopathy10.0MPZ, PMP22
41cerebritis10.0
42spasticity10.0
43conotruncal heart malformations10.0MPZ, PMP22
44dowling-degos disease10.0ACTA1, FHL1
45phototoxic dermatitis10.0MPZ, PMP22
46muscular dystrophy, rigid spine, 110.0ACTA1, FHL1
47microcephaly and chorioretinopathy 110.0ACTA1, NEB
48white piedra9.9MPZ, PMP22
49substance-induced psychosis9.9MPZ, PMP22
50hypoglossal nerve neoplasm9.9ACTA1, NEB

Graphical network of the top 20 diseases related to Foot Drop:



Diseases related to foot drop

Symptoms & Phenotypes for Foot Drop

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MGI Mouse Phenotypes related to Foot Drop according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.3ACTA1, FHL1, MPZ, NEB, PMP22
2MP:00053698.0ACTA1, FHL1, NEB, PMP22

Drugs & Therapeutics for Foot Drop

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Drugs for Foot Drop (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 94)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Hyaluronic acidapproved, vet_approvedPhase 44699004-61-953477741, 24759
Synonyms:
Hyaluronan
Hyaluronate
Hyaluronic acid
Hylartil
Hyruan Plus
Luronit
 
Macronan
Mucoitin
Nutra-HAF
Q 5AQ
Sepracoat
Sepragel Sinus
Sofast
Synvisc
2
AcetylcholineapprovedPhase 480551-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
3
Bimatoprostapproved, investigationalPhase 4133155206-00-15311027
Synonyms:
(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1e,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
155206-00-1
15M
267244-98-4
5-Heptenamide,7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ehtyl-,(5Z)
AC1NSJUW
AGN 192024
AGN-192024
Bimataprost [USAN:INN:BAN]
Bimatoprost
Bimatoprost (JAN/USAN/INN)
Bimatoprost [USAN:INN:BAN]
Bimatoprostum
 
CHEBI:39562
CHEBI:51230
CHEMBL1200963
CID5311027
D02724
DB00905
DB06863
I06-1275
I06-1277
LS-181817
Latisse
Lumigan
Lumigan (TN)
NCGC00181745-01
UNII-QXS94885MZ
ZINC04474405
bimatoprostum
4
Mannitolapproved, investigationalPhase 428069-65-8453, 6251
Synonyms:
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
(L)-Mannitol
1,2,3,4,5,6-Hexanehexol
123897-58-5
133-43-7
15719_ALDRICH
15719_RIEDEL
33440_RIEDEL
33440_SIGMA
36413-61-3
4-01-00-02841 (Beilstein Handbook Reference)
5149-40-6
63559_FLUKA
63559_SIGMA
63560_FLUKA
63565_FLUKA
63565_SIGMA
69-65-8
75398-80-0
85085-15-0
87-78-5
AB1002081
AC-12776
AC1L1M49
AC1Q28E5
AI3-19511
AR-1J3861
Ambap69-65-8
BRN 1721898
C00392
C6H14O6
CCRIS 369
CHEBI:16899
CHEMBL689
CID6251
Cordycepate
Cordycepic acid
D-(-)-Mannitol
D-Mannitol
D-Mannitol (JP15)
D-mannite
D-mannitol
D00062
D008353
DL-Mannitol
Diosmol
ED1D1E61-FEFB-430A-AFDC-D1F4A957FC3D
EINECS 200-711-8
EINECS 201-770-2
Fraxinine
HSDB 714
Hexahydroxyhexane
Hexanhexol
Invenex
Isotol
LS-1588
LS-89250
M0044
M1902_SIGMA
M4125_SIAL
M8429_SIAL
M9546_SIAL
M9647_SIAL
MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER
MANNITOL 15% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.45%
 
MANNITOL 25%
MANNITOL 5% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.12%
MLS001335977
MLS001335978
MTL
Manicol
Manitol
Maniton S
Maniton-S
Manna Sugar
Manna sugar
Mannazucker
Mannidex
Mannidex 16700
Mannigen
Mannistol
Mannit
Mannit p
Mannite
Mannitol
Mannitol (USP)
Mannitol (VAN)
Mannitol 10%
Mannitol 10% In Plastic Container
Mannitol 15%
Mannitol 15% In Plastic Container
Mannitol 20%
Mannitol 20% In Plastic Container
Mannitol 5%
Mannitol 5% In Plastic Container
Mannitol [USAN]
Mannitolum
Mannogem 2080
Marine Crystal
Marine crystal
MolPort-003-927-039
Mushroom sugar
NCGC00164246-01
NCI-C50362
NSC 407017
NSC 9256
OSMITROL 10% IN WATER IN PLASTIC CONTAINER
OSMITROL 15% IN WATER IN PLASTIC CONTAINER
OSMITROL 20% IN WATER IN PLASTIC CONTAINER
OSMITROL 5% IN WATER IN PLASTIC CONTAINER
Osmitrol
Osmitrol (TN)
Osmitrol 10% In Water
Osmitrol 15% In Water
Osmitrol 20% In Water
Osmitrol 5% In Water
Osmofundin
Osmosal
Resectisol
Resectisol In Plastic Container
SDM No. 35
SMR000857324
SORBITOL-MANNITOL IN PLASTIC CONTAINER
Sorbitol-Mannitol
TL806434
UNII-3OWL53L36A
ZINC02041302
bmse000099
cpd without stereochemical designation
e 421
e-421
e421
manita
mannitol
5
RibavirinapprovedPhase 4100336791-04-537542
Synonyms:
1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide
36791-04-5
437710-49-1
66510-90-5
AA-504/07617051
AB00430481
AC1L1XXZ
AC1Q1IDC
AC1Q4ZGS
AKOS001715163
BB_NC-0567
BPBio1_001195
BRN 0892462
BSPBio_001085
BSPBio_003352
C-Virin
CHEMBL1643
CID37542
Copegus
Copegus (TN)
Cotronak
D00423
DB00811
DRG-0028
DivK1c_000782
Drug: Ribavirin
EU-0101063
FT-0082885
HMS2090L15
HMS2094O09
HMS502H04
HSDB 6513
ICN-1229
IDI1_000782
KBio1_000782
KBio2_002328
KBio2_004896
KBio2_007464
KBio3_002854
KBioGR_001804
KBioSS_002331
KS-1104
LS-1241
Lopac0_001063
MLS000028486
MLS002222317
MolPort-002-507-104
MolPort-002-885-856
NCGC00090726-01
NCGC00090726-03
NCGC00090726-04
NCGC00090726-05
NCGC00090726-06
NCGC00090726-07
NINDS_000782
NSC 163039
 
NSC163039
Prestwick3_000993
R 9644
R-964
R9644_SIGMA
RBV
RG-964
RIBAV
RTC
RTCA
RTP
Ravanex
Rebetol
Rebetol (TN)
Rebetron
Rebretron
Ribacine
Ribamide
Ribamidil
Ribamidyl
Ribasphere
Ribasphere (TN)
Ribav
Ribavirin
Ribavirin (JAN/USP/INN)
Ribavirin Capsules
Ribavirin Triphosphate
Ribavirin [USAN:INN]
Ribavirin-TP
Ribavirina
Ribavirina [INN-Spanish]
Ribavirine
Ribavirine [INN-French]
Ribavirinum
Ribavirinum [INN-Latin]
Ribovirin
Ro 20-9963/000
Ro-20-9963
S2504_Selleck
SCH 18908
SMP1_000261
SMR000058315
SPECTRUM1503938
SR-01000076112-3
Spectrum3_001876
Spectrum4_001252
Spectrum5_002075
Spectrum_001826
Tribavirin
UNII-49717AWG6K
Varazid
Vilona
Viramid
Viramide
Virazid
Virazide
Virazole
Virazole (Ribavirin) Inhalation Solution
Virazole (TN)
Virazole 5'-triphosphate
ZINC01035331
ribavirin
6
Folic Acidapproved, nutraceutical, vet_approvedPhase 4, Phase 3, Phase 2439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
7
Thiamineapproved, nutraceutical, vet_approvedPhase 410159-43-81130
Synonyms:
100660-17-1
115461-66-0
1sbr
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydrox yethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethylthiazolium chloride, monohydrochloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride monohydrochloride
3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
3-(4-AMINO-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium
3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride
3[(4-Amino-2-methyl-5-pyrimidinyl)-methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
55463-15-5
57777-32-9
59-43-8
67-03-8
AC-11683
AC1L1ASK
AC1L1LOC
AC1LAODT
AC1Q4V9Q
AI3-18993
AKOS000668650
AR-1L8201
Aneurin
Aneurine
Antiberiberi factor
Apatate drape
Apate drops
B-Amin
BAS 00266240
BPBio1_000686
BSPBio_000622
Beatine
Bedome
Begiolan
Beivon
Benerva
Bequin
Berin
Betabion
Betalin S
Betaxin
Bethiamin
Bethiazine
Beuion
Bevitex
Bevitine
Bewon
Biamine
Bithiamin
Biuno
Bivatin
Bivita
C00378
C12H17N4OS
CCRIS 1906
CCRIS 5823
CHEBI:18385
CHEBI:33283
CHEBI:49105
CHEMBL1547
CHEMBL1588
CID1130
CID517305
CID6042
Cernevit-12
Chloride-hydrochloride salt of thiamine
Clotiamina
D08580
DB00152
EINECS 200-425-3
EINECS 200-641-8
Eskapen
Eskaphen
FEMA No. 3322
 
HSDB 220
Hybee
I14-14339
LS-3226
LT00233141
Lixa-beta
MLS001304099
Metabolin
MolPort-000-722-048
MolPort-001-920-086
MolPort-002-052-059
NChemBio.2007.13-comp10
NSC 36226
NSC36226
Oryzanin
Oryzanine
Prestwick0_000631
Prestwick1_000631
Prestwick2_000631
Prestwick3_000631
SBB058094
SMP1_000084
SMR000718788
SPBio_002841
ST095175
Slowten
THD
THIAMIN, VITAMIN B1
Thiadoxine
Thiamin
Thiamin dichloride
Thiaminal
Thiamine
Thiamine (INN)
Thiamine HCL
Thiamine [INN:BAN]
Thiamine chloride
Thiamine chloride hydrochloride
Thiamine dichloride
Thiamine hydrochloride [JAN]
Thiamine monochloride
Thiamine monohydrochloride
Thiamine, chloride
Thiamine, chloride, hydrochloride
Thiamine, monohydrochloride
Thiaminium
Thiaminium chloride hydrochloride
Thiaminum
Thiaminum [INN-Latin]
Thiamol
Thiavit
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethyl, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride (1:1)
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-chloride
Tiamidon
Tiamina
Tiamina [INN-Spanish]
Tiaminal
TimTec1_000613
Trophite
UNII-X66NSO3N35
VIB
Vetalin S
Vinothiam
Vitamin B1
Vitamin B1 (TN)
Vitamin B1 hydrochloride (VAN)
Vitaneurin
Vitaneuron
ZINC00049153
[5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methylpyrimidin-4-yl]azanium dichloride
bmse000274
nchembio.121-comp5
thiamin
thiamine
thiamine(1+)
thiamine(1+) ion
thiaminium
vitamin B1
vitamin b1(thiamine)
8Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 323689
9Pharmaceutical SolutionsPhase 48192
10Antihypertensive AgentsPhase 4, Phase 2, Phase 34207
11Neurotransmitter AgentsPhase 4, Phase 2, Phase 318340
12Vitamin B ComplexPhase 4, Phase 3, Phase 24337
13VitaminsPhase 4, Phase 25282
14ViscosupplementsPhase 4390
15abobotulinumtoxinAPhase 4652
16Protective AgentsPhase 4, Phase 27443
17AntimetabolitesPhase 4, Phase 312054
18Neuromuscular AgentsPhase 41180
19Ophthalmic SolutionsPhase 41140
20incobotulinumtoxinAPhase 4662
21onabotulinumtoxinAPhase 4652
22Botulinum Toxins, Type APhase 4657
23Adjuvants, ImmunologicPhase 42554
24Botulinum ToxinsPhase 4697
25Cholinergic AgentsPhase 43992
26Trace ElementsPhase 4, Phase 26001
27Anti-Infective AgentsPhase 422062
28Antiviral AgentsPhase 49967
29MicronutrientsPhase 4, Phase 26001
30FolateNutraceuticalPhase 4, Phase 3, Phase 24392
31Vitamin B9NutraceuticalPhase 4, Phase 3, Phase 24392
32ThiaminNutraceuticalPhase 4101
33
OndansetronapprovedPhase 2, Phase 332699614-02-54595
Synonyms:
(RS)-1,2,3,9-Tetrahydro-9-methyl-3-(2-methylimidazol-1-ylmethyl)carbazol-4-one
1,2,3,9-Tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one
103639-04-9 (mono-hydrochloride dihydrate)
108303-49-7
116002-70-1
9-Methyl-3-(2-methyl-imidazol-1-ylmethyl)-1,2,3,9-tetrahydro-carbazol-4-one
9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one
9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one
99614-01-4 (mono-hydrochloride)
99614-02-5
AB00373674
AC1L1IIM
AKOS000599484
Apo-ondansetron
BAS 00717177
BPBio1_001118
BRD-A19736161-001-01-8
BRD-A19736161-003-03-0
BRN 3622981
BSPBio_001016
C07325
C18H19N3O
CBDivE_008994
CHEMBL46
CID4595
CPD001307702
D00456
DB00904
DESMETHYLONDANSETRON
GR 38032
GR 38032X
GR-38032F
GR38032F
HMS2090H16
I06-0687
I06-1329
 
L000456
LS-172305
LS-51878
MolPort-001-944-253
NCI60_022780
Novo-ondansetron
Ondansetron
Ondansetron (JAN/USP/INN)
Ondansetron [USAN:INN:BAN]
Ondansetron, (+,-)-Isomer
Oprea1_435466
Oprea1_852372
PHL-ondansetron
PMS-ondansetron
Prestwick0_001058
Prestwick1_001058
Prestwick2_001058
Prestwick3_001058
Ratio-ondansetron
SAM002589958
SN-307
SPBio_002938
STK370548
STOCK4S-10990
Sandoz ondansetron
TL8006071
TimTec1_001750
UNII-4AF302ESOS
ZOFRAN IN PLASTIC CONTAINER
Zofran
Zofran ODT
Zofran ODT (TN)
Zofran odt
Zophren
Zudan
ondansetron
ondansetron (Zofran)
34
Tofacitinibapproved, investigationalPhase 3108477600-75-2
Synonyms:
 
Tasocitinib
Tofacitinibum
35
MethotrexateapprovedPhase 315511959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
36
leucovorinapproved, NutraceuticalPhase 3323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
37Psychotropic DrugsPhase 2, Phase 36430
38
SerotoninPhase 2, Phase 3362750-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
39Serotonin AntagonistsPhase 2, Phase 31409
40Serotonin AgentsPhase 2, Phase 33156
41Tranquilizing AgentsPhase 2, Phase 34265
42Anti-Anxiety AgentsPhase 2, Phase 31885
43AnestheticsPhase 2, Phase 3, Early Phase 19596
44Gastrointestinal AgentsPhase 2, Phase 38402
45AntipruriticsPhase 2, Phase 3841
46AntiemeticsPhase 2, Phase 34022
47Antipsychotic AgentsPhase 2, Phase 32401
48Autonomic AgentsPhase 2, Phase 310150
49Central Nervous System DepressantsPhase 2, Phase 313403
50Dermatologic AgentsPhase 2, Phase 35806

Interventional clinical trials:

(show top 50)    (show all 54)
idNameStatusNCT IDPhase
1Patient Satisfaction Study of Combined Facial Treatment With BOTOX® Cosmetic, JUVÉDERM® and LATISSE® (HARMONY Study)CompletedNCT02176356Phase 4
2Effect of Xiaoer Jiebiao Oral Liquid on Hand-foot-mouth DiseaseRecruitingNCT02328651Phase 4
3Thiamin Deficiency in Obese Thai ChildrenRecruitingNCT02464865Phase 4
4Effects of Functional Electrical Stimulation on Gait in Children With Cerebral PalsyNot yet recruitingNCT02462018Phase 4
5Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy ParturientsUnknown statusNCT01414777Phase 2, Phase 3
6Evaluation of the Safety and Performance of the NESS L300 Plus SystemCompletedNCT01237860Phase 3
7Comparing The Effectiveness And Safety Of 2 Doses Of An Experimental Drug, CP-690,550, To Methotrexate (MTX) In Patients With Rheumatoid Arthritis Who Have Not Previously Received MTXCompletedNCT01039688Phase 3
8Functional Electrical Stimulation for Footdrop in HemiparesisCompletedNCT00148343Phase 2
9Effect of Robot-assisted Training on Foot Drop in Multiple SclerosisCompletedNCT00872053Phase 1, Phase 2
10Extracorporeal Shockwave Treatment for Chronic Soft Tissue WoundsCompletedNCT00545896Phase 2
11The Role of Cytokines on Growth Hormone Suppression in Premenopausal Women With Rheumatoid Arthritis and the Effect of Treatment With EtanerceptCompletedNCT00034060Phase 2
12A Phase I/II Double-blind Safety and Efficacy Evaluation of Nowarta110 in Patients With Plantar WartsCompletedNCT02338336Phase 1, Phase 2
13Essential Oils for Enhancing QOL in ASDRecruitingNCT02543203Phase 2
14Marched Pair Study Conventional Doxorubicin(DOX) Versus Pegylated Liposomal Doxorubicin(PLD) Neoadjuvant ChemotherapyRecruitingNCT02953184Phase 2
15Targeted Lower Extremity Joint TrainingTerminatedNCT00765544Phase 1, Phase 2
16Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in StrokeUnknown statusNCT02199795Phase 1
17Pilot Study Assessing the Feasibility of Treating Foot Drop With the Neurostep™ System.CompletedNCT00860210Phase 1
18Electrical Stimulation for Recovery of Ankle Dorsiflexion in Chronic Stroke SurvivorsCompletedNCT01029912Phase 1
19Comparison of Different Treatment Methods for Gait Rehabilitation of Sub-Acute Post Stroke Patients With Dropped FootUnknown statusNCT01876030
20Effect of FES Interventions on Gait Dynamics in Stroke PopulationUnknown statusNCT01952613
21A Clinical Trial to Evaluate the Effectiveness and Safety of Xiyanping Injection in the Treatment of Mild Type of Hand, Foot, and Mouth DiseaseUnknown statusNCT01182025
22Eccentric Exercise for Chronic Mid-portion Achilles TendinopathyUnknown statusNCT01225497
23Treating Foot Drop in People With Multiple Sclerosis Using Electrical StimulationCompletedNCT02123537
24Walking With FES or AFO in People With MS With Foot DropCompletedNCT01977287
25Evaluation of Dual Channel vs. Single Channel FES for DropfootCompletedNCT02494323
26Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot DropCompletedNCT01138995
27Functional Electrical Stimulation for People With Multiple Sclerosis Who Experience Foot DropCompletedNCT01914016
28Clinical Study to Evaluate the Implantation of the ActiGait Drop Foot Stimulator SystemCompletedNCT01116466
29Effects of Targeted Lower Extremity Joint Training on Multiple Sclerosis (MS) Gait AbnormalitiesCompletedNCT00906737
30WalkAide Compared to Ankle-Foot Orthosis (AFO) in Stroke PatientsCompletedNCT01087957
31Tibial Nerve Versus Sciatic Nerve BlockCompletedNCT01415193
32Efficacy of the WalkAide and AFOs for CVACompletedNCT00216320
33Comparison Between Implanted Functional Electrical Stimulation and Foot OrthosisCompletedNCT01415700
34Approach to Continuous Sciatic Nerve Block for Orthopedic Procedures in Day Surgery With Two Different TechniquesCompletedNCT02029404
35Study of Changes in the Feet With PregnancyCompletedNCT01868074
36Effects of Weight Loss on Foot Structure and Function in Obese Adults: A Pilot StudyCompletedNCT01782144
37Treatment of Painful Diabetic Neuropathy With Photon StimulationCompletedNCT00539175
38PAHA Study: Psychological Active and Healthy AgeingCompletedNCT01966562
39Ankle Robot to Reduce Foot-drop in StrokeRecruitingNCT02483676
40Multi-pad FES System for Drop Foot TreatmentRecruitingNCT02729636Early Phase 1
41Extramembranous and Interosseous Technique of Tibialis Posterior Tendon TransferRecruitingNCT01751503
42Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.RecruitingNCT02693834
43Acute Nerve Decompression Versus Non-operative Treatment for Peroneal Nerve Palsy Following Primary Total Knee ArthroplastyRecruitingNCT02856958
44Clinical Effects of Peroneal Nerve Functional Electrical Stimulation (WalkAide[R]) for Chronic Stroke PatientsRecruitingNCT02897752
45Interactive Exoskeleton Robot for Walking - Ankle JointRecruitingNCT02471248
46Pathological Basis of MRI Signal Changes in Multiple SclerosisRecruitingNCT02659956
47Do Simple Running Technique Changes Reduce Pain and Change Injury Causing MechanicsRecruitingNCT03067545
48Effects on Pes Planus Exercise Training Mixed With Play on Pre-school ChildrenRecruitingNCT03151538
49Chromosome 18 Clinical Research CenterRecruitingNCT00227253
50Evaluation of Usability and Human Factors in the Novus SystemNot yet recruitingNCT02738242

Search NIH Clinical Center for Foot Drop

Genetic Tests for Foot Drop

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Anatomical Context for Foot Drop

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MalaCards organs/tissues related to Foot Drop:

36
Brain, Bone, Spinal cord, Prostate, B cells, Myeloid, Skin

Publications for Foot Drop

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Articles related to Foot Drop:

(show top 50)    (show all 307)
idTitleAuthorsYear
1
An Unusual Presentation of Right-Sided Sciatica with Foot Drop. (27217963)
2016
2
Preoperative motor strength and time to surgery are the most important predictors of improvement in foot drop due to degenerative lumbar disease. (26810531)
2016
3
An Unusual Cause of Foot Drop: Peroneal Extraneural Ganglion Cyst. (27648065)
2016
4
Foot drop following closed reduction of a total hip replacement. (27005799)
2016
5
Progressive foot drop caused by below-knee compression stocking after spinal surgery. (27617106)
2016
6
Foot drop of central origin: a misleading alteration of nerve conduction study. (26728269)
2016
7
A 39-Year-Old Postpartum Woman With Foot Drop and Shortness of Breath. (26867857)
2016
8
Cat Bite: An Unusual Cause of Foot Drop. (26836381)
2016
9
Functional electrical stimulation versus ankle foot orthoses for foot-drop: A meta-analysis of orthotic effects. (27563700)
2016
10
An Unusual Postoperative Neuropathy: Foot Drop Contralateral to the Lateral Decubitus Position. (27580410)
2016
11
Surgical outcome of foot drop caused by common peroneal nerve injuries; is the glass half full or half empty? (27106843)
2016
12
A Modified Approach of Percutaneous Endoscopic Lumbar Discectomy (PELD) for Far Lateral Disc Herniation at L5-S1 with Foot Drop. (26839673)
2016
13
A Case of Alkaptonuria with Degenerative Collagenous Plaques and Foot Drop. (27904192)
2016
14
Bilateral Central Foot Drop in a Pediatric Patient. (27427994)
2016
15
Peroneal Intraneural Ganglia Formation Causing Foot Drop in Children: A Clinical Perspective. (26721618)
2016
16
Malignant" foot drop: Enzinger epithelioid sarcoma of the common fibular nerve. (27061383)
2016
17
Total Hip Arthroplasty Complicated by a Gluteal Hematoma Resulting in Acute Foot Drop. (26966944)
2016
18
Popliteal Artery Pseudoaneurysm with Secondary Chronic Common Peroneal Nerve Neuropathy and Foot Drop after Total Knee Replacement. (26140945)
2015
19
Gout and foot drop. (26453107)
2015
20
Endometriosis of the lumbosacral plexus: report of a case with foot drop and chronic pelvic pain. (25697329)
2015
21
The impact of walking speed on the effects of functional electrical stimulation for foot drop in people with multiple sclerosis. (25826047)
2015
22
Misunderstanding of foot drop in a patient with charcot-marie-tooth disease and lumbar disk herniation. (25932299)
2015
23
WITHDRAWN: Rehabilitation interventions for foot drop in neuromuscular disease. (25927103)
2015
24
Changes in center of pressure displacement with the use of a foot drop stimulator in individuals with stroke. (26003198)
2015
25
Changes in plantar load distribution and gait pattern following foot drop correction in leprosy affected patients. (26665356)
2015
26
Palpable purpura with foot drop: Common presentations in an uncommon disease. (25821734)
2015
27
Foot drop following spinal anaesthesia. (26323747)
2015
28
Acute bilateral isolated foot drop: Report of two cases. (25972945)
2015
29
Bilateral foot-drop as predominant symptom in nebulin (NEB) gene related "core-rod" congenital myopathy. (26403434)
2015
30
Effects of Lower-Leg Kinesiology Taping on Balance Ability in Stroke Patients with Foot Drop. (26579200)
2015
31
Spatially distributed sequential array stimulation of tibial anterior muscle for foot drop correction. (26737024)
2015
32
WITHDRAWN: Rehabilitation interventions for foot drop in neuromuscular disease. (25687881)
2015
33
Statin-induced bilateral foot drop in a case of hypothyroidism. (26425013)
2015
34
A basic study on quantitative evaluation of 3-dimensional foot contact with an inertial sensor for FES foot drop correction. (26737826)
2015
35
Peroneal Stimulation for Foot Drop After Stroke: A Systematic Review. (26035725)
2015
36
Sonographic evaluation of common peroneal neuropathy in patients with foot drop. (25792587)
2015
37
Isolated Painless Foot Drop due to Cerebral Infarction Mimicking Lumbar Radiculopathy: A Case Report. (26512287)
2015
38
Conversion Disorder; an Unusual Etiology of Unilateral Foot Drop. (26179836)
2015
39
Clinical reasoning: a 51-year-old woman with acute foot drop. (25688156)
2015
40
Foot drop. (25918354)
2015
41
Outcomes of the Bridle Procedure for the Treatment of Foot Drop. (26160388)
2015
42
Posterior tibial tendon transfer improves function for foot drop after knee dislocation. (24566891)
2014
43
Managing spastic foot drop after stroke. (24628965)
2014
44
EMG of the tibialis anterior demonstrates a training effect after utilization of a foot drop stimulator. (24990033)
2014
45
Cerebral infarction presenting with unilateral isolated foot drop. (25368770)
2014
46
Comparison of walking energy cost between an anterior and a posterior ankle-foot orthosis in people with foot drop. (24953375)
2014
47
Poststroke muscle architectural parameters of the tibialis anterior and the potential implications for rehabilitation of foot drop. (25133011)
2014
48
Bilateral Ankle and Subtalar Joint Fusion Secondary to Guillain BarrAc-Induced Foot Drop. (25128306)
2014
49
Comparative analysis and quantitative evaluation of ankle-foot orthoses for foot drop in chronic hemiparetic patients. (25184801)
2014
50
The unique case of foot drop secondary to a large ovarian cyst. (24447226)
2014

Variations for Foot Drop

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Expression for genes affiliated with Foot Drop

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Search GEO for disease gene expression data for Foot Drop.

Pathways for genes affiliated with Foot Drop

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Pathways related to Foot Drop according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.4MPZ, PMP22
29.1ACTA1, NEB

GO Terms for genes affiliated with Foot Drop

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Cellular components related to Foot Drop according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1sarcomereGO:00300179.1ACTA1, NEB

Biological processes related to Foot Drop according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle organ developmentGO:00075179.9FHL1, NEB
2muscle filament slidingGO:00300499.7ACTA1, NEB
3myelinationGO:00425529.4MPZ, PMP22

Sources for Foot Drop

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet