HDDD
MCID: FRN027
MIFTS: 13

Frontotemporal Dementia, Ubiquitin-Positive (HDDD) malady

Rare diseases, Mental diseases categories

Summaries for Frontotemporal Dementia, Ubiquitin-Positive

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34MalaCards
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MalaCards: Frontotemporal Dementia, Ubiquitin-Positive, also known as dementia, hereditary dysphasic disinhibition, is related to frontotemporal dementia and grn-related frontotemporal dementia.

Aliases & Classifications for Frontotemporal Dementia, Ubiquitin-Positive

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Sources:
44NIH Rare Diseases, 23GTR, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Mental diseases


Aliases & Descriptions:

frontotemporal dementia, ubiquitin-positive 44 23 63
dementia, hereditary dysphasic disinhibition 44
hddd 44


Related Diseases for Frontotemporal Dementia, Ubiquitin-Positive

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18GeneCards, 19GeneDecks
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Diseases related to Frontotemporal Dementia, Ubiquitin-Positive via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1frontotemporal dementia10.4
2grn-related frontotemporal dementia10.4

Symptoms for Frontotemporal Dementia, Ubiquitin-Positive

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Drugs & Therapeutics for Frontotemporal Dementia, Ubiquitin-Positive

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Frontotemporal Dementia, Ubiquitin-Positive

Drug clinical trials:

Search ClinicalTrials for Frontotemporal Dementia, Ubiquitin-Positive

Search NIH Clinical Center for Frontotemporal Dementia, Ubiquitin-Positive

Search CenterWatch for Frontotemporal Dementia, Ubiquitin-Positive

Genetic Tests for Frontotemporal Dementia, Ubiquitin-Positive

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23GTR
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Genetic tests related to Frontotemporal Dementia, Ubiquitin-Positive:

id Genetic test Affiliating Genes
1 Frontotemporal Dementia, Ubiquitin-Positive23

Anatomical Context for Frontotemporal Dementia, Ubiquitin-Positive

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Animal Models for Frontotemporal Dementia, Ubiquitin-Positive or affiliated genes

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Publications for Frontotemporal Dementia, Ubiquitin-Positive

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Variations for Frontotemporal Dementia, Ubiquitin-Positive

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Sources:
1 National Center for Biotechnology Information (Clinvar)
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Clinvar genetic disease variations for Frontotemporal Dementia, Ubiquitin-Positive:

1
id Gene Name Type Significance SNP ID Assembly Location
1GRNNM_002087.2(GRN): c.373C> T (p.Gln125Ter)single nucleotide variantPathogenicrs63750077GRCh37Chr 17, 42427619: 42427619
2GRNNM_002087.2(GRN): c.2T> C (p.Met1Thr)single nucleotide variantPathogenicrs63751006GRCh37Chr 17, 42426534: 42426534
3GRNNM_002087.2(GRN): c.3G> A (p.Met1Ile)single nucleotide variantPathogenicrs63750331GRCh37Chr 17, 42426535: 42426535
4GRNNM_002087.2(GRN): c.26C> A (p.Ala9Asp)single nucleotide variantPathogenicrs63751243GRCh37Chr 17, 42426558: 42426558
5GRNNM_002087.2(GRN): c.1477C> T (p.Arg493Ter)single nucleotide variantPathogenicrs63751294GRCh37Chr 17, 42429772: 42429772
6GRNNM_002087.2(GRN): c.813_816delCACT (p.Thr272Serfs)deletionPathogenicrs63749877GRCh37Chr 17, 42428509: 42428512

Expression for genes affiliated with Frontotemporal Dementia, Ubiquitin-Positive

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Sources:
16Gene Expression Omnibus DataSets
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Search GEO for disease gene expression data for Frontotemporal Dementia, Ubiquitin-Positive.

Pathways for genes affiliated with Frontotemporal Dementia, Ubiquitin-Positive

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Compounds for genes affiliated with Frontotemporal Dementia, Ubiquitin-Positive

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GO Terms for genes affiliated with Frontotemporal Dementia, Ubiquitin-Positive

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Products for genes affiliated with Frontotemporal Dementia, Ubiquitin-Positive

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Frontotemporal Dementia, Ubiquitin-Positive

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet