MCID: FNC002
MIFTS: 18

Functional Diarrhea malady

Summaries for Functional Diarrhea

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32MalaCards
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MalaCards: Functional Diarrhea is related to diarrhea and syndromic diarrhea. An important gene associated with Functional Diarrhea is ITM2B (integral membrane protein 2B), and among its related pathways is Disease. Affiliated tissues include colon.

Aliases & Classifications for Functional Diarrhea

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8Disease Ontology, 60UMLS, 56SNOMED-CT, 27ICD9CM
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Aliases & Descriptions:

functional diarrhea 8 60


External Ids:

Disease Ontology8 DOID:11371
SNOMED-CT56 47812002
ICD9CM27 564.5

Related Diseases for Functional Diarrhea

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Functional Diarrhea via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1diarrhea10.5
2syndromic diarrhea10.2
3irritable bowel syndrome10.2
4dyspepsia9.9
5constipation9.9

Graphical network of diseases related to Functional Diarrhea:



Diseases related to functional diarrhea

Clinical Features for Functional Diarrhea

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Drugs & Therapeutics for Functional Diarrhea

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Functional Diarrhea

Drug clinical trials:

Search ClinicalTrials for Functional Diarrhea

Search NIH Clinical Center for Functional Diarrhea

Search CenterWatch for Functional Diarrhea

Genetic Tests for Functional Diarrhea

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Anatomical Context for Functional Diarrhea

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32MalaCards
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MalaCards organs/tissues related to Functional Diarrhea:

32
Colon

Animal Models for Functional Diarrhea or affiliated genes

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Publications for Functional Diarrhea

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50PubMed
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Articles related to Functional Diarrhea:

(show all 27)
idTitleAuthorsYear
1
Functional Characterization of Bovine Viral Diarrhea Virus Nonstructural Protein 5A by Reverse Genetic Analysis and Live Cell Imaging. (24131714)
2014
2
Dual Functions of Lactobacillus acidophilus NCFM as Protection Against Rotavirus Diarrhea. (24126832)
2014
3
A controlled trial of gluten-free diet in patients with irritable bowel syndrome-diarrhea: effects on bowel frequency and intestinal function. (23357715)
2013
4
Effect of Bovine Viral Diarrhea Virus on the ovarian functionality and in vitro reproductive performance of persistently infected heifers. (23726223)
2013
5
The effect of acute serotonergic modulation on rectal motor function in diarrhea-predominant irritable bowel syndrome and healthy controls. (22890209)
2012
6
Epidemiology of functional diarrhea and comparison with diarrhea-predominant irritable bowel syndrome: a population-based survey in China. (22937091)
2012
7
Functional diarrhea. (22917168)
2012
8
Association of HLA-DQ gene with bowel transit, barrier function, and inflammation in irritable bowel syndrome with diarrhea. (23042942)
2012
9
Serotonin signaling is altered in irritable bowel syndrome with diarrhea but not in functional dyspepsia in pediatric age patients. (20303355)
2010
10
Development of functional diarrhea, constipation, irritable bowel syndrome, and dyspepsia during and after traveling outside the USA. (17549631)
2008
11
First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome. (18614545)
2008
12
Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein. (17185998)
2007
13
Treatment of functional diarrhea. (16836952)
2006
14
Functional diarrhea. (16168232)
2005
15
Function of von Willebrand factor in children with diarrhea-associated hemolytic-uremic syndrome (D+ HUS). (11446662)
2001
16
Effects of probiotic administration upon the composition and enzymatic activity of human fecal microbiota in patients with irritable bowel syndrome or functional diarrhea. (11686387)
2001
17
Bile acid malabsorption in microscopic colitis and in previously unexplained functional chronic diarrhea. (11680602)
2001
18
Inhibition of gastric secretion relieves diarrhea and postprandial urgency associated with irritable bowel syndrome or functional diarrhea. (10505731)
1999
19
A pilot study of motility and tone of the left colon in patients with diarrhea due to functional disorders and dysautonomia. (9040210)
1997
20
Rapid gastric emptying in patients with functional diarrhea. (9121178)
1997
21
Colonic motility and functional diarrhea. (1622483)
1992
22
Effect of eating on colonic motility and transit in patients with functional diarrhea. Simultaneous scintigraphic and manometric evaluations. (1936800)
1991
23
Composition of the intestinal fluid and the functional jejunoileal junction in secretory diarrhea of cholera in children. (6768219)
1980
24
Chronic diarrhea in an adult with hypokalemic nephropathy and osteomalacia due to a functioning ganglioneuroblastoma. (4961457)
1967
25
Chronic diarrhea in an adult with hypokalemic nephropathy and osteomalacia due to functioning ganglioneuroblastoma. (6021377)
1967
26
Functional diarrhea: an analysis of the clinical and roentgen manifestations. (13397691)
1956
27
Alterations in colonic function in man under stress; hypomotility of the sigmoid colon, and its relationship to the mechanism of functional diarrhea. (15421433)
1950

Genetic Variations for Functional Diarrhea

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Expression for genes affiliated with Functional Diarrhea

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Functional Diarrhea

Search GEO for disease gene expression data for Functional Diarrhea.

Pathways for genes affiliated with Functional Diarrhea

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53Reactome
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Pathways related to Functional Diarrhea according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1FGF19, ITM2B

Compounds for genes affiliated with Functional Diarrhea

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GO Terms for genes affiliated with Functional Diarrhea

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16Gene Ontology
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Cellular components related to Functional Diarrhea according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.1FGF19, ITM2B

Biological processes related to Functional Diarrhea according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nervous system developmentGO:0073999.1FGF19, ITM2B

Products for genes affiliated with Functional Diarrhea

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Functional Diarrhea

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet