MCID: FNC002
MIFTS: 17

Functional Diarrhea malady

Summaries for Functional Diarrhea

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33MalaCards
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MalaCards: Functional Diarrhea is related to irritable bowel syndrome and dyspepsia. An important gene associated with Functional Diarrhea is ITM2B (integral membrane protein 2B), and among its related pathways is Disease. Affiliated tissues include colon.

Aliases & Classifications for Functional Diarrhea

Sources:
8Disease Ontology, 61UMLS, 57SNOMED-CT, 27ICD9CM
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Aliases & Descriptions:

functional diarrhea 8 61


External Ids:

Disease Ontology8 DOID:11371
SNOMED-CT57 47812002
ICD9CM27 564.5

Related Diseases for Functional Diarrhea

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Functional Diarrhea via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1irritable bowel syndrome10.2
2dyspepsia9.9
3micro syndrome9.9

Clinical Features for Functional Diarrhea

Drugs & Therapeutics for Functional Diarrhea

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Functional Diarrhea

Drug clinical trials:

Search ClinicalTrials for Functional Diarrhea

Search NIH Clinical Center for Functional Diarrhea

Search CenterWatch for Functional Diarrhea

Genetic Tests for Functional Diarrhea

Anatomical Context for Functional Diarrhea

Sources:
33MalaCards
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MalaCards organs/tissues related to Functional Diarrhea:

33
Colon

Animal Models for Functional Diarrhea or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Functional Diarrhea

Sources:
51PubMed
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Articles related to Functional Diarrhea:

(show all 20)
idTitleAuthorsYear
1
Functional Characterization of Bovine Viral Diarrhea Virus Nonstructural Protein 5A by Reverse Genetic Analysis and Live Cell Imaging. (24131714)
2014
2
Effect of Bovine Viral Diarrhea Virus on the ovarian functionality and in vitro reproductive performance of persistently infected heifers. (23726223)
2013
3
Epidemiology of functional diarrhea and comparison with diarrhea-predominant irritable bowel syndrome: a population-based survey in China. (22937091)
2012
4
Functional diarrhea. (22917168)
2012
5
Serotonin signaling is altered in irritable bowel syndrome with diarrhea but not in functional dyspepsia in pediatric age patients. (20303355)
2010
6
Development of functional diarrhea, constipation, irritable bowel syndrome, and dyspepsia during and after traveling outside the USA. (17549631)
2008
7
First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome. (18614545)
2008
8
Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein. (17185998)
2007
9
Treatment of functional diarrhea. (16836952)
2006
10
Functional diarrhea. (16168232)
2005
11
Effects of probiotic administration upon the composition and enzymatic activity of human fecal microbiota in patients with irritable bowel syndrome or functional diarrhea. (11686387)
2001
12
Bile acid malabsorption in microscopic colitis and in previously unexplained functional chronic diarrhea. (11680602)
2001
13
Inhibition of gastric secretion relieves diarrhea and postprandial urgency associated with irritable bowel syndrome or functional diarrhea. (10505731)
1999
14
A pilot study of motility and tone of the left colon in patients with diarrhea due to functional disorders and dysautonomia. (9040210)
1997
15
Rapid gastric emptying in patients with functional diarrhea. (9121178)
1997
16
Colonic motility and functional diarrhea. (1622483)
1992
17
Effect of eating on colonic motility and transit in patients with functional diarrhea. Simultaneous scintigraphic and manometric evaluations. (1936800)
1991
18
Composition of the intestinal fluid and the functional jejunoileal junction in secretory diarrhea of cholera in children. (6768219)
1980
19
Functional diarrhea: an analysis of the clinical and roentgen manifestations. (13397691)
1956
20
Alterations in colonic function in man under stress; hypomotility of the sigmoid colon, and its relationship to the mechanism of functional diarrhea. (15421433)
1950

Genetic Variations for Functional Diarrhea

Expression for genes affiliated with Functional Diarrhea

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Functional Diarrhea

Search GEO for disease gene expression data for Functional Diarrhea.

Pathways for genes affiliated with Functional Diarrhea

Sources:
54Reactome
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Pathways related to Functional Diarrhea according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1FGF19, ITM2B

Compounds for genes affiliated with Functional Diarrhea

GO Terms for genes affiliated with Functional Diarrhea

Sources:
16Gene Ontology
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Cellular components related to Functional Diarrhea according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.1FGF19, ITM2B

Biological processes related to Functional Diarrhea according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nervous system developmentGO:0073999.1FGF19, ITM2B

Products for genes affiliated with Functional Diarrhea

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Functional Diarrhea

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet