MCID: FNC012
MIFTS: 15

Functioning Pancreatic Endocrine Tumor

Categories: Rare diseases, Endocrine diseases

Aliases & Classifications for Functioning Pancreatic Endocrine Tumor

MalaCards integrated aliases for Functioning Pancreatic Endocrine Tumor:

Name: Functioning Pancreatic Endocrine Tumor 50

Classifications:



Summaries for Functioning Pancreatic Endocrine Tumor

MalaCards based summary : Functioning Pancreatic Endocrine Tumor is related to non-functioning pancreatic endocrine tumor and pancreatitis. The drugs Pancrelipase and pancreatin have been mentioned in the context of this disorder. Affiliated tissues include endothelial, pancreas and liver.

Related Diseases for Functioning Pancreatic Endocrine Tumor

Diseases related to Functioning Pancreatic Endocrine Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 non-functioning pancreatic endocrine tumor 12.4
2 pancreatitis 9.8

Symptoms & Phenotypes for Functioning Pancreatic Endocrine Tumor

Drugs & Therapeutics for Functioning Pancreatic Endocrine Tumor

Drugs for Functioning Pancreatic Endocrine Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 78)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pancrelipase Approved Phase 4,Phase 2,Phase 1,Early Phase 1 53608-75-6
2 pancreatin Phase 4,Phase 2,Phase 1,Early Phase 1
3 Gastrointestinal Agents Phase 4,Phase 2,Early Phase 1
4 Fluorodeoxyglucose F18 Phase 4
5
Cisplatin Approved Phase 2, Phase 3 15663-27-1 84093 441203 2767
6
Gemcitabine Approved Phase 2, Phase 3,Phase 1 95058-81-4 60750
7
Somatostatin Approved Phase 3,Phase 2 38916-34-6, 51110-01-1 53481605
8
Fluorouracil Approved Phase 2, Phase 3 51-21-8 3385
9
Heparin Approved, Investigational Phase 2, Phase 3 9005-49-6 772 46507594
10
Levoleucovorin Approved Phase 2, Phase 3 68538-85-2
11
Sunitinib Approved, Investigational Phase 3 341031-54-7, 557795-19-4 5329102
12
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
13
leucovorin Approved, Nutraceutical Phase 2, Phase 3 58-05-9 143 6006
14 Anti-Infective Agents Phase 2, Phase 3,Phase 1
15 Antimetabolites Phase 2, Phase 3,Phase 1
16 Antimetabolites, Antineoplastic Phase 2, Phase 3,Phase 1
17 Antiviral Agents Phase 2, Phase 3,Phase 1
18 Immunosuppressive Agents Phase 2, Phase 3,Phase 1
19 Hormone Antagonists Phase 3,Phase 2,Early Phase 1
20 Hormones Phase 3,Phase 2,Early Phase 1
21 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Early Phase 1
22 Antidotes Phase 2, Phase 3
23 calcium heparin Phase 2, Phase 3
24 Hematinics Phase 2, Phase 3
25 Micronutrients Phase 2, Phase 3,Phase 1
26 Protective Agents Phase 2, Phase 3,Phase 1
27 Trace Elements Phase 2, Phase 3,Phase 1
28 Vitamin B Complex Phase 2, Phase 3
29 Vitamins Phase 2, Phase 3,Phase 1
30 Angiogenesis Inhibitors Phase 3,Phase 2,Phase 1
31 Angiogenesis Modulating Agents Phase 3,Phase 2,Phase 1
32 Folate Nutraceutical Phase 2, Phase 3
33 Vitamin B9 Nutraceutical Phase 2, Phase 3
34
Omeprazole Approved, Investigational, Vet_approved Phase 2 73590-58-6 4594
35
Pantoprazole Approved Phase 2 102625-70-7 4679
36
Capecitabine Approved, Investigational Phase 2,Phase 1 154361-50-9 60953
37
Streptozocin Approved Phase 2 18883-66-4 29327
38
Bevacizumab Approved, Investigational Phase 2 216974-75-3
39
Octreotide Approved, Investigational Phase 2 83150-76-9 383414 6400441
40
Lenalidomide Approved Phase 1, Phase 2 191732-72-6 216326
41
Everolimus Approved Phase 2 159351-69-6 6442177
42
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
43
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353
44 Pancreatic Polypeptide Investigational Phase 2 59763-91-6
45
Curcumin Investigational Phase 2 458-37-7 969516
46 Interferon-alpha Phase 2
47 interferons Phase 2
48 Antacids Phase 2
49 Anti-Ulcer Agents Phase 2
50
Proton pump inhibitors Phase 2

Interventional clinical trials:

(show all 49)

id Name Status NCT ID Phase Drugs
1 Nonfunctional Pancreatic NET and PET Imaging Recruiting NCT02621541 Phase 4
2 Clinical Effectiveness of Serum Chromogranin A Levels on Diagnostic of Pancreatic Neuroendocrine Tumors Active, not recruiting NCT02759718 Phase 4
3 Pancreatic Enzyme Suppletion in Pancreatic Cancer Withdrawn NCT01401387 Phase 4
4 Chemotherapy With or Without Enoxaparin in Pancreatic Cancer Completed NCT00785421 Phase 2, Phase 3 enoxaparin;chemotherapy with LMWH - enoxaparin;only chemotherapy
5 Non-functioning Pancreatic Neuroendocrine Tumors in MEN1: Somatostatin Analogs Versus NO Treatment Not yet recruiting NCT02705651 Phase 3 Somatostatin-Analog
6 A Study Of Sunitinib Compared To Placebo For Patients With Advanced Pancreatic Islet Cell Tumors Terminated NCT00428597 Phase 3 sunitinib malate;Placebo
7 Cisplatin, Metronomic Low-Dose Interferon Alfa, Gemcitabine, and Fever-Range Whole-Body Hyperthermia in Treating Patients With Inoperable or Metastatic Pancreatic Cancer Unknown status NCT00082862 Phase 2 cisplatin;gemcitabine hydrochloride
8 The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid Completed NCT00001191 Phase 2 Pantoprazole;Omeprazole
9 Capecitabine and Streptozocin With or Without Cisplatin in Treating Patients With Unresectable or Metastatic Neuroendocrine Tumors Completed NCT00602082 Phase 2 capecitabine;cisplatin;streptozocin
10 68Ga-DOTATATE PET Scan in Neuroendocrine Cancer Completed NCT01396382 Phase 2
11 A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Endocrine Tumors of the Gastrointestinal Tract. Completed NCT00448136 Phase 2 bevacizumab [Avastin];5 FU;Streptozotocin;Xeloda
12 High Dose Somatostatin Analogues in Neuroendocrine Tumors Completed NCT00990535 Phase 2 Octreotide-LAR
13 Trial of Curcumin in Advanced Pancreatic Cancer Completed NCT00094445 Phase 2 Curcumin
14 Lenalidomide and Gemcitabine as First-line Treatment in Patients With Pancreatic Cancer Completed NCT01547260 Phase 1, Phase 2 Gemzar;Revlimid
15 Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas (PC04) Recruiting NCT02598349 Phase 2 Capecitabine
16 Determine Function of Antroquinonol in Combination With SOC in First Line Metastatic Pancreatic Cancer Not yet recruiting NCT03310632 Phase 1, Phase 2 Antroquinonol
17 High Intensity Focused Ultrasound Tumor Treatment for Pancreatic Cancer Pain Suspended NCT00637364 Phase 1, Phase 2
18 Pharmacokinetically Guided Everolimus in Patients With Breast Cancer, Pancreatic Neuroendocrine Tumors, or Kidney Cancer Terminated NCT02273752 Phase 2 Everolimus
19 A Research Trial of High Dose Vitamin C and Chemotherapy for Metastatic Pancreatic Cancer Completed NCT01049880 Phase 1 Gemcitabine with escalating ascorbic acid
20 ABR-217620 in Patients With Advanced Non-Small Cell Lung Cancer, Renal Clear Cell Carcinoma or Pancreatic Cancer Completed NCT00056537 Phase 1 ABR-217620
21 Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor Withdrawn NCT02831179 Phase 1 Capecitabine;Temozolomide;Veliparib
22 Ga68-DOTA-NOC-PET Imaging of Neuroendocrine Tumors Unknown status NCT00569738
23 Effect of Chewing Gum on Postoperative Bowel Function Following Upper GI Tract Cancer Surgery Unknown status NCT02260128
24 Integrated Positron Emission Tomography - Computed Tomography (PET-CT) in Patients With Pancreatic Cancer Unknown status NCT00885248
25 Secretin-Assisted Computed Tomography Scan and Magnetic Resonance Imaging in Improving Pancreatic Tumor Conspicuity Unknown status NCT01371240 Early Phase 1 Secretin Synthetic Human (RG1068)
26 Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease Completed NCT00970970
27 Functional Magnetic Resonance Imaging of Pancreatic Cancer: a Feasibility and Reproducibility Study Completed NCT01995240 Gadobutrol
28 Exercise Intervention Study for Pancreatic Cancer Patients Completed NCT01977066
29 Fatigue and Pancreas and Bile Duct Cancer Study Completed NCT00902759 Early Phase 1
30 Depression, Cytokines and Pancreatic Cancer Completed NCT00582699
31 Oral Microbiome and Pancreatic Cancer Completed NCT03302637
32 Clinical Trial of Pancreatic Cancer in Stockholm. Completed NCT02162823
33 Evaluation of Radiological Response of Pancreatic Neuroendocrine Tumors: Comparison Between the Choi and the RECIST Criteria Recruiting NCT02841865
34 Diet and Exercise After Pancreatic Cancer Recruiting NCT03187028
35 Evaluation of Prognosis With Integrated MRI/PET in Patients With Pancreatic Cancer Recruiting NCT02550847
36 A Comparative Clinical Research on Single Roux-en-Y and Traditional Roux-en-Y of Pancreaticojejunostomy-choledochojejunostomy For Treatment of Obstruction of Pancreatic Duct and Bile Duct Recruiting NCT01926717
37 Prospectively Defining Metastatic Pancreatic Ductal Adenocarcinoma Subtypes by Comprehensive Genomic Analysis Recruiting NCT02869802
38 In Vitro Models of Liver and Pancreatic Cancer Recruiting NCT02436564
39 Study of Changes and Characteristics of Genes in Patients With Pancreatic Cancer for Better Treatment Selection Recruiting NCT02750657
40 DCE MRI in Diagnosing Patients With Pancreatic Cancer Recruiting NCT02070705
41 EVIS - Ex-vivo Assessment of T-lymphocyte Homing in Primary Pancreatic Cancer Recruiting NCT02695966
42 Effect of Islet Autotransplantation Compared to Oral Antidiabetic Drug. Active, not recruiting NCT01922492 Oral anti-diabetic drugs
43 Gastroenteral-Pancreatic Neuroendocrine Tumors in Taiwan Enrolling by invitation NCT02102893
44 Nonfunctioning Small (≤2 cm) Neuroendocrine Pancreatic Incidentaloma Not yet recruiting NCT03022188
45 Pilot Project for Cardiopulmonary and Functional Evaluation in Patients With Pancreatic Cancer Associated Cachexia Terminated NCT02580422
46 Secretin-enhanced Magnetic Resonance Cholangiopancreatography (S-MRCP) and Pancreatic Function Following Surgery Withdrawn NCT01094535 Synthetic Human Secretin
47 Comparison of Secretin-enhanced Magnetic Resonance Cholangiopancreatography (S-MRCP) to Endoscopic Pancreatic Function Test (ePFT) in Diagnosing Pancreatic Exocrine Insufficiency Withdrawn NCT01094600 Synthetic Human Secretin
48 Distal Pancreatectomy With Partial Splenectomy for Pancreatic Tumors Withdrawn NCT01412684
49 Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV Pancreatic or Ovarian Cancer Withdrawn NCT01927393

Search NIH Clinical Center for Functioning Pancreatic Endocrine Tumor

Genetic Tests for Functioning Pancreatic Endocrine Tumor

Anatomical Context for Functioning Pancreatic Endocrine Tumor

MalaCards organs/tissues related to Functioning Pancreatic Endocrine Tumor:

39
Endothelial, Pancreas, Liver, Pancreatic Islet, Testes, Breast, Kidney

Publications for Functioning Pancreatic Endocrine Tumor

Articles related to Functioning Pancreatic Endocrine Tumor:

id Title Authors Year
1
Non-functioning pancreatic endocrine tumors: eleven-year experience in a single institute. ( 24965405 )
2014
2
ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: functional pancreatic endocrine tumor syndromes. ( 22261919 )
2012

Variations for Functioning Pancreatic Endocrine Tumor

Expression for Functioning Pancreatic Endocrine Tumor

Search GEO for disease gene expression data for Functioning Pancreatic Endocrine Tumor.

Pathways for Functioning Pancreatic Endocrine Tumor

GO Terms for Functioning Pancreatic Endocrine Tumor

Sources for Functioning Pancreatic Endocrine Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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